Contrast-enhanced ultrasound (CEUS) in Crohn’s disease: technique, image interpretation and clinical applications

Background Recent meta-analysis has demonstrated no significant differences in diagnostic accuracy among different imaging techniques (US, MRI and CT) in the evaluation of Crohn’s disease (CD). High-resolution bowel ultrasound has emerged as an alternative imaging technique for the diagnosis and fol...
Ausführliche Beschreibung

Gespeichert in:

Autor*in:	Ripollés, Tomás [verfasserIn] Martínez-Pérez, María J. Blanc, Esther Delgado, Fructuoso Vizuete, José Paredes, José M. Vilar, José

Format:	E-Artikel
Sprache:	Englisch

Erschienen:	2011

Schlagwörter:	Crohn’s disease Ultrasound Contrast-enhanced ultrasound Ultrasound contrast agents Inflammatory bowel disease

Anmerkung:	© European Society of Radiology 2011

Übergeordnetes Werk:	Enthalten in: Insights into imaging - Berlin : Springer, 2010, 2(2011), 6 vom: 10. Aug., Seite 639-652
Übergeordnetes Werk:	volume:2 ; year:2011 ; number:6 ; day:10 ; month:08 ; pages:639-652

Links:	Volltext

DOI / URN:	10.1007/s13244-011-0124-1

Katalog-ID:	SPR031000827

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520			\|a Background Recent meta-analysis has demonstrated no significant differences in diagnostic accuracy among different imaging techniques (US, MRI and CT) in the evaluation of Crohn’s disease (CD). High-resolution bowel ultrasound has emerged as an alternative imaging technique for the diagnosis and follow-up of patients with CD, being as accurate as CT and MR for detecting intramural and extramural extension of the disease. B-Mode US can evaluate the localization and length of the affected intestinal segments and allow identification of transmural complications, stenosis and intestinal obstruction. Doppler techniques are tools that visualize and quantify bowel vascularization. Contrast-enhanced ultrasound (CEUS) is a new technique that involves IV administration of an ultrasound contrast agent with real-time examination, providing an accurate depiction of the bowel wall microvascularization and the perienteric tissues. The introduction of imaging quantification techniques enables an objective quantitative measurement of the enhancement. Method and results The article reviews the technique, sonographic findings, advantages and limitations, and clinical applications of contrast-enhanced US in the evaluation of Cohn’s disease. Current CEUS applications in CD are: CD activity assessment, evaluation of inflammatory masses, distinguishing phlegmons from abscesses, characterization of stenosis by differentiating fibrosis from inflammation, monitoring the efficacy of drug treatments and improving the detection of disease recurrence. Conclusion CEUS is an emerging technique that is part of the entire sonographic evaluation, with a role in the diagnosis and follow-up of CD, thus improving therapy planning and monitoring of the efficacy of treatment.
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allfields	10.1007/s13244-011-0124-1 doi (DE-627)SPR031000827 (SPR)s13244-011-0124-1-e DE-627 ger DE-627 rakwb eng Ripollés, Tomás verfasserin aut Contrast-enhanced ultrasound (CEUS) in Crohn’s disease: technique, image interpretation and clinical applications 2011 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier © European Society of Radiology 2011 Background Recent meta-analysis has demonstrated no significant differences in diagnostic accuracy among different imaging techniques (US, MRI and CT) in the evaluation of Crohn’s disease (CD). High-resolution bowel ultrasound has emerged as an alternative imaging technique for the diagnosis and follow-up of patients with CD, being as accurate as CT and MR for detecting intramural and extramural extension of the disease. B-Mode US can evaluate the localization and length of the affected intestinal segments and allow identification of transmural complications, stenosis and intestinal obstruction. Doppler techniques are tools that visualize and quantify bowel vascularization. Contrast-enhanced ultrasound (CEUS) is a new technique that involves IV administration of an ultrasound contrast agent with real-time examination, providing an accurate depiction of the bowel wall microvascularization and the perienteric tissues. The introduction of imaging quantification techniques enables an objective quantitative measurement of the enhancement. Method and results The article reviews the technique, sonographic findings, advantages and limitations, and clinical applications of contrast-enhanced US in the evaluation of Cohn’s disease. Current CEUS applications in CD are: CD activity assessment, evaluation of inflammatory masses, distinguishing phlegmons from abscesses, characterization of stenosis by differentiating fibrosis from inflammation, monitoring the efficacy of drug treatments and improving the detection of disease recurrence. Conclusion CEUS is an emerging technique that is part of the entire sonographic evaluation, with a role in the diagnosis and follow-up of CD, thus improving therapy planning and monitoring of the efficacy of treatment. Crohn’s disease (dpeaa)DE-He213 Ultrasound (dpeaa)DE-He213 Contrast-enhanced ultrasound (dpeaa)DE-He213 Ultrasound contrast agents (dpeaa)DE-He213 Inflammatory bowel disease (dpeaa)DE-He213 Martínez-Pérez, María J. aut Blanc, Esther aut Delgado, Fructuoso aut Vizuete, José aut Paredes, José M. aut Vilar, José aut Enthalten in Insights into imaging Berlin : Springer, 2010 2(2011), 6 vom: 10. Aug., Seite 639-652 (DE-627)621547425 (DE-600)2543323-4 1869-4101 nnns volume:2 year:2011 number:6 day:10 month:08 pages:639-652 https://dx.doi.org/10.1007/s13244-011-0124-1 lizenzpflichtig Volltext GBV_USEFLAG_A SYSFLAG_A GBV_SPRINGER SSG-OLC-PHA GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_2014 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4277 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 2 2011 6 10 08 639-652
spelling	10.1007/s13244-011-0124-1 doi (DE-627)SPR031000827 (SPR)s13244-011-0124-1-e DE-627 ger DE-627 rakwb eng Ripollés, Tomás verfasserin aut Contrast-enhanced ultrasound (CEUS) in Crohn’s disease: technique, image interpretation and clinical applications 2011 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier © European Society of Radiology 2011 Background Recent meta-analysis has demonstrated no significant differences in diagnostic accuracy among different imaging techniques (US, MRI and CT) in the evaluation of Crohn’s disease (CD). High-resolution bowel ultrasound has emerged as an alternative imaging technique for the diagnosis and follow-up of patients with CD, being as accurate as CT and MR for detecting intramural and extramural extension of the disease. B-Mode US can evaluate the localization and length of the affected intestinal segments and allow identification of transmural complications, stenosis and intestinal obstruction. Doppler techniques are tools that visualize and quantify bowel vascularization. Contrast-enhanced ultrasound (CEUS) is a new technique that involves IV administration of an ultrasound contrast agent with real-time examination, providing an accurate depiction of the bowel wall microvascularization and the perienteric tissues. The introduction of imaging quantification techniques enables an objective quantitative measurement of the enhancement. Method and results The article reviews the technique, sonographic findings, advantages and limitations, and clinical applications of contrast-enhanced US in the evaluation of Cohn’s disease. Current CEUS applications in CD are: CD activity assessment, evaluation of inflammatory masses, distinguishing phlegmons from abscesses, characterization of stenosis by differentiating fibrosis from inflammation, monitoring the efficacy of drug treatments and improving the detection of disease recurrence. Conclusion CEUS is an emerging technique that is part of the entire sonographic evaluation, with a role in the diagnosis and follow-up of CD, thus improving therapy planning and monitoring of the efficacy of treatment. Crohn’s disease (dpeaa)DE-He213 Ultrasound (dpeaa)DE-He213 Contrast-enhanced ultrasound (dpeaa)DE-He213 Ultrasound contrast agents (dpeaa)DE-He213 Inflammatory bowel disease (dpeaa)DE-He213 Martínez-Pérez, María J. aut Blanc, Esther aut Delgado, Fructuoso aut Vizuete, José aut Paredes, José M. aut Vilar, José aut Enthalten in Insights into imaging Berlin : Springer, 2010 2(2011), 6 vom: 10. Aug., Seite 639-652 (DE-627)621547425 (DE-600)2543323-4 1869-4101 nnns volume:2 year:2011 number:6 day:10 month:08 pages:639-652 https://dx.doi.org/10.1007/s13244-011-0124-1 lizenzpflichtig Volltext GBV_USEFLAG_A SYSFLAG_A GBV_SPRINGER SSG-OLC-PHA GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_2014 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4277 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 2 2011 6 10 08 639-652
allfields_unstemmed	10.1007/s13244-011-0124-1 doi (DE-627)SPR031000827 (SPR)s13244-011-0124-1-e DE-627 ger DE-627 rakwb eng Ripollés, Tomás verfasserin aut Contrast-enhanced ultrasound (CEUS) in Crohn’s disease: technique, image interpretation and clinical applications 2011 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier © European Society of Radiology 2011 Background Recent meta-analysis has demonstrated no significant differences in diagnostic accuracy among different imaging techniques (US, MRI and CT) in the evaluation of Crohn’s disease (CD). High-resolution bowel ultrasound has emerged as an alternative imaging technique for the diagnosis and follow-up of patients with CD, being as accurate as CT and MR for detecting intramural and extramural extension of the disease. B-Mode US can evaluate the localization and length of the affected intestinal segments and allow identification of transmural complications, stenosis and intestinal obstruction. Doppler techniques are tools that visualize and quantify bowel vascularization. Contrast-enhanced ultrasound (CEUS) is a new technique that involves IV administration of an ultrasound contrast agent with real-time examination, providing an accurate depiction of the bowel wall microvascularization and the perienteric tissues. The introduction of imaging quantification techniques enables an objective quantitative measurement of the enhancement. Method and results The article reviews the technique, sonographic findings, advantages and limitations, and clinical applications of contrast-enhanced US in the evaluation of Cohn’s disease. Current CEUS applications in CD are: CD activity assessment, evaluation of inflammatory masses, distinguishing phlegmons from abscesses, characterization of stenosis by differentiating fibrosis from inflammation, monitoring the efficacy of drug treatments and improving the detection of disease recurrence. Conclusion CEUS is an emerging technique that is part of the entire sonographic evaluation, with a role in the diagnosis and follow-up of CD, thus improving therapy planning and monitoring of the efficacy of treatment. Crohn’s disease (dpeaa)DE-He213 Ultrasound (dpeaa)DE-He213 Contrast-enhanced ultrasound (dpeaa)DE-He213 Ultrasound contrast agents (dpeaa)DE-He213 Inflammatory bowel disease (dpeaa)DE-He213 Martínez-Pérez, María J. aut Blanc, Esther aut Delgado, Fructuoso aut Vizuete, José aut Paredes, José M. aut Vilar, José aut Enthalten in Insights into imaging Berlin : Springer, 2010 2(2011), 6 vom: 10. Aug., Seite 639-652 (DE-627)621547425 (DE-600)2543323-4 1869-4101 nnns volume:2 year:2011 number:6 day:10 month:08 pages:639-652 https://dx.doi.org/10.1007/s13244-011-0124-1 lizenzpflichtig Volltext GBV_USEFLAG_A SYSFLAG_A GBV_SPRINGER SSG-OLC-PHA GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_2014 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4277 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 2 2011 6 10 08 639-652
allfieldsGer	10.1007/s13244-011-0124-1 doi (DE-627)SPR031000827 (SPR)s13244-011-0124-1-e DE-627 ger DE-627 rakwb eng Ripollés, Tomás verfasserin aut Contrast-enhanced ultrasound (CEUS) in Crohn’s disease: technique, image interpretation and clinical applications 2011 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier © European Society of Radiology 2011 Background Recent meta-analysis has demonstrated no significant differences in diagnostic accuracy among different imaging techniques (US, MRI and CT) in the evaluation of Crohn’s disease (CD). High-resolution bowel ultrasound has emerged as an alternative imaging technique for the diagnosis and follow-up of patients with CD, being as accurate as CT and MR for detecting intramural and extramural extension of the disease. B-Mode US can evaluate the localization and length of the affected intestinal segments and allow identification of transmural complications, stenosis and intestinal obstruction. Doppler techniques are tools that visualize and quantify bowel vascularization. Contrast-enhanced ultrasound (CEUS) is a new technique that involves IV administration of an ultrasound contrast agent with real-time examination, providing an accurate depiction of the bowel wall microvascularization and the perienteric tissues. The introduction of imaging quantification techniques enables an objective quantitative measurement of the enhancement. Method and results The article reviews the technique, sonographic findings, advantages and limitations, and clinical applications of contrast-enhanced US in the evaluation of Cohn’s disease. Current CEUS applications in CD are: CD activity assessment, evaluation of inflammatory masses, distinguishing phlegmons from abscesses, characterization of stenosis by differentiating fibrosis from inflammation, monitoring the efficacy of drug treatments and improving the detection of disease recurrence. Conclusion CEUS is an emerging technique that is part of the entire sonographic evaluation, with a role in the diagnosis and follow-up of CD, thus improving therapy planning and monitoring of the efficacy of treatment. Crohn’s disease (dpeaa)DE-He213 Ultrasound (dpeaa)DE-He213 Contrast-enhanced ultrasound (dpeaa)DE-He213 Ultrasound contrast agents (dpeaa)DE-He213 Inflammatory bowel disease (dpeaa)DE-He213 Martínez-Pérez, María J. aut Blanc, Esther aut Delgado, Fructuoso aut Vizuete, José aut Paredes, José M. aut Vilar, José aut Enthalten in Insights into imaging Berlin : Springer, 2010 2(2011), 6 vom: 10. Aug., Seite 639-652 (DE-627)621547425 (DE-600)2543323-4 1869-4101 nnns volume:2 year:2011 number:6 day:10 month:08 pages:639-652 https://dx.doi.org/10.1007/s13244-011-0124-1 lizenzpflichtig Volltext GBV_USEFLAG_A SYSFLAG_A GBV_SPRINGER SSG-OLC-PHA GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_2014 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4277 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 2 2011 6 10 08 639-652
allfieldsSound	10.1007/s13244-011-0124-1 doi (DE-627)SPR031000827 (SPR)s13244-011-0124-1-e DE-627 ger DE-627 rakwb eng Ripollés, Tomás verfasserin aut Contrast-enhanced ultrasound (CEUS) in Crohn’s disease: technique, image interpretation and clinical applications 2011 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier © European Society of Radiology 2011 Background Recent meta-analysis has demonstrated no significant differences in diagnostic accuracy among different imaging techniques (US, MRI and CT) in the evaluation of Crohn’s disease (CD). High-resolution bowel ultrasound has emerged as an alternative imaging technique for the diagnosis and follow-up of patients with CD, being as accurate as CT and MR for detecting intramural and extramural extension of the disease. B-Mode US can evaluate the localization and length of the affected intestinal segments and allow identification of transmural complications, stenosis and intestinal obstruction. Doppler techniques are tools that visualize and quantify bowel vascularization. Contrast-enhanced ultrasound (CEUS) is a new technique that involves IV administration of an ultrasound contrast agent with real-time examination, providing an accurate depiction of the bowel wall microvascularization and the perienteric tissues. The introduction of imaging quantification techniques enables an objective quantitative measurement of the enhancement. Method and results The article reviews the technique, sonographic findings, advantages and limitations, and clinical applications of contrast-enhanced US in the evaluation of Cohn’s disease. Current CEUS applications in CD are: CD activity assessment, evaluation of inflammatory masses, distinguishing phlegmons from abscesses, characterization of stenosis by differentiating fibrosis from inflammation, monitoring the efficacy of drug treatments and improving the detection of disease recurrence. Conclusion CEUS is an emerging technique that is part of the entire sonographic evaluation, with a role in the diagnosis and follow-up of CD, thus improving therapy planning and monitoring of the efficacy of treatment. Crohn’s disease (dpeaa)DE-He213 Ultrasound (dpeaa)DE-He213 Contrast-enhanced ultrasound (dpeaa)DE-He213 Ultrasound contrast agents (dpeaa)DE-He213 Inflammatory bowel disease (dpeaa)DE-He213 Martínez-Pérez, María J. aut Blanc, Esther aut Delgado, Fructuoso aut Vizuete, José aut Paredes, José M. aut Vilar, José aut Enthalten in Insights into imaging Berlin : Springer, 2010 2(2011), 6 vom: 10. Aug., Seite 639-652 (DE-627)621547425 (DE-600)2543323-4 1869-4101 nnns volume:2 year:2011 number:6 day:10 month:08 pages:639-652 https://dx.doi.org/10.1007/s13244-011-0124-1 lizenzpflichtig Volltext GBV_USEFLAG_A SYSFLAG_A GBV_SPRINGER SSG-OLC-PHA GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_2014 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4277 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 2 2011 6 10 08 639-652
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author	Ripollés, Tomás
spellingShingle	Ripollés, Tomás misc Crohn’s disease misc Ultrasound misc Contrast-enhanced ultrasound misc Ultrasound contrast agents misc Inflammatory bowel disease Contrast-enhanced ultrasound (CEUS) in Crohn’s disease: technique, image interpretation and clinical applications
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topic_title	Contrast-enhanced ultrasound (CEUS) in Crohn’s disease: technique, image interpretation and clinical applications Crohn’s disease (dpeaa)DE-He213 Ultrasound (dpeaa)DE-He213 Contrast-enhanced ultrasound (dpeaa)DE-He213 Ultrasound contrast agents (dpeaa)DE-He213 Inflammatory bowel disease (dpeaa)DE-He213
topic	misc Crohn’s disease misc Ultrasound misc Contrast-enhanced ultrasound misc Ultrasound contrast agents misc Inflammatory bowel disease
topic_unstemmed	misc Crohn’s disease misc Ultrasound misc Contrast-enhanced ultrasound misc Ultrasound contrast agents misc Inflammatory bowel disease
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title	Contrast-enhanced ultrasound (CEUS) in Crohn’s disease: technique, image interpretation and clinical applications
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title_full	Contrast-enhanced ultrasound (CEUS) in Crohn’s disease: technique, image interpretation and clinical applications
author_sort	Ripollés, Tomás
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author_browse	Ripollés, Tomás Martínez-Pérez, María J. Blanc, Esther Delgado, Fructuoso Vizuete, José Paredes, José M. Vilar, José
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title_sort	contrast-enhanced ultrasound (ceus) in crohn’s disease: technique, image interpretation and clinical applications
title_auth	Contrast-enhanced ultrasound (CEUS) in Crohn’s disease: technique, image interpretation and clinical applications
abstract	Background Recent meta-analysis has demonstrated no significant differences in diagnostic accuracy among different imaging techniques (US, MRI and CT) in the evaluation of Crohn’s disease (CD). High-resolution bowel ultrasound has emerged as an alternative imaging technique for the diagnosis and follow-up of patients with CD, being as accurate as CT and MR for detecting intramural and extramural extension of the disease. B-Mode US can evaluate the localization and length of the affected intestinal segments and allow identification of transmural complications, stenosis and intestinal obstruction. Doppler techniques are tools that visualize and quantify bowel vascularization. Contrast-enhanced ultrasound (CEUS) is a new technique that involves IV administration of an ultrasound contrast agent with real-time examination, providing an accurate depiction of the bowel wall microvascularization and the perienteric tissues. The introduction of imaging quantification techniques enables an objective quantitative measurement of the enhancement. Method and results The article reviews the technique, sonographic findings, advantages and limitations, and clinical applications of contrast-enhanced US in the evaluation of Cohn’s disease. Current CEUS applications in CD are: CD activity assessment, evaluation of inflammatory masses, distinguishing phlegmons from abscesses, characterization of stenosis by differentiating fibrosis from inflammation, monitoring the efficacy of drug treatments and improving the detection of disease recurrence. Conclusion CEUS is an emerging technique that is part of the entire sonographic evaluation, with a role in the diagnosis and follow-up of CD, thus improving therapy planning and monitoring of the efficacy of treatment. © European Society of Radiology 2011
abstractGer	Background Recent meta-analysis has demonstrated no significant differences in diagnostic accuracy among different imaging techniques (US, MRI and CT) in the evaluation of Crohn’s disease (CD). High-resolution bowel ultrasound has emerged as an alternative imaging technique for the diagnosis and follow-up of patients with CD, being as accurate as CT and MR for detecting intramural and extramural extension of the disease. B-Mode US can evaluate the localization and length of the affected intestinal segments and allow identification of transmural complications, stenosis and intestinal obstruction. Doppler techniques are tools that visualize and quantify bowel vascularization. Contrast-enhanced ultrasound (CEUS) is a new technique that involves IV administration of an ultrasound contrast agent with real-time examination, providing an accurate depiction of the bowel wall microvascularization and the perienteric tissues. The introduction of imaging quantification techniques enables an objective quantitative measurement of the enhancement. Method and results The article reviews the technique, sonographic findings, advantages and limitations, and clinical applications of contrast-enhanced US in the evaluation of Cohn’s disease. Current CEUS applications in CD are: CD activity assessment, evaluation of inflammatory masses, distinguishing phlegmons from abscesses, characterization of stenosis by differentiating fibrosis from inflammation, monitoring the efficacy of drug treatments and improving the detection of disease recurrence. Conclusion CEUS is an emerging technique that is part of the entire sonographic evaluation, with a role in the diagnosis and follow-up of CD, thus improving therapy planning and monitoring of the efficacy of treatment. © European Society of Radiology 2011
abstract_unstemmed	Background Recent meta-analysis has demonstrated no significant differences in diagnostic accuracy among different imaging techniques (US, MRI and CT) in the evaluation of Crohn’s disease (CD). High-resolution bowel ultrasound has emerged as an alternative imaging technique for the diagnosis and follow-up of patients with CD, being as accurate as CT and MR for detecting intramural and extramural extension of the disease. B-Mode US can evaluate the localization and length of the affected intestinal segments and allow identification of transmural complications, stenosis and intestinal obstruction. Doppler techniques are tools that visualize and quantify bowel vascularization. Contrast-enhanced ultrasound (CEUS) is a new technique that involves IV administration of an ultrasound contrast agent with real-time examination, providing an accurate depiction of the bowel wall microvascularization and the perienteric tissues. The introduction of imaging quantification techniques enables an objective quantitative measurement of the enhancement. Method and results The article reviews the technique, sonographic findings, advantages and limitations, and clinical applications of contrast-enhanced US in the evaluation of Cohn’s disease. Current CEUS applications in CD are: CD activity assessment, evaluation of inflammatory masses, distinguishing phlegmons from abscesses, characterization of stenosis by differentiating fibrosis from inflammation, monitoring the efficacy of drug treatments and improving the detection of disease recurrence. Conclusion CEUS is an emerging technique that is part of the entire sonographic evaluation, with a role in the diagnosis and follow-up of CD, thus improving therapy planning and monitoring of the efficacy of treatment. © European Society of Radiology 2011
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title_short	Contrast-enhanced ultrasound (CEUS) in Crohn’s disease: technique, image interpretation and clinical applications
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author2	Martínez-Pérez, María J. Blanc, Esther Delgado, Fructuoso Vizuete, José Paredes, José M. Vilar, José
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High-resolution bowel ultrasound has emerged as an alternative imaging technique for the diagnosis and follow-up of patients with CD, being as accurate as CT and MR for detecting intramural and extramural extension of the disease. B-Mode US can evaluate the localization and length of the affected intestinal segments and allow identification of transmural complications, stenosis and intestinal obstruction. Doppler techniques are tools that visualize and quantify bowel vascularization. Contrast-enhanced ultrasound (CEUS) is a new technique that involves IV administration of an ultrasound contrast agent with real-time examination, providing an accurate depiction of the bowel wall microvascularization and the perienteric tissues. The introduction of imaging quantification techniques enables an objective quantitative measurement of the enhancement. Method and results The article reviews the technique, sonographic findings, advantages and limitations, and clinical applications of contrast-enhanced US in the evaluation of Cohn’s disease. Current CEUS applications in CD are: CD activity assessment, evaluation of inflammatory masses, distinguishing phlegmons from abscesses, characterization of stenosis by differentiating fibrosis from inflammation, monitoring the efficacy of drug treatments and improving the detection of disease recurrence. 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Contrast-enhanced ultrasound (CEUS) in Crohn’s disease: technique, image interpretation and clinical applications

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