Bulk evaluation and comparison of radiotherapy treatment plans for breast cancer
Abstract This study provides a bulk, retrospective analysis of 151 breast and chest wall radiotherapy treatment plans, as a small-scale demonstration of the potential breadth and value of the information that may be obtained from clinical data mining. The treatments were planned at three centres bel...
Ausführliche Beschreibung
Gespeichert in:
| Autor*in: |
Kairn, T. [verfasserIn] |
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| Format: |
E-Artikel |
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| Sprache: |
Englisch |
| Erschienen: |
2016 |
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| Schlagwörter: |
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| Anmerkung: |
© Australasian College of Physical Scientists and Engineers in Medicine 2016 |
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| Übergeordnetes Werk: |
Enthalten in: Australasian physical & engineering sciences in medicine - Cham : Springer, 2001, 39(2016), 3 vom: 20. Juni, Seite 633-644 |
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| Übergeordnetes Werk: |
volume:39 ; year:2016 ; number:3 ; day:20 ; month:06 ; pages:633-644 |
| Links: |
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| DOI / URN: |
10.1007/s13246-016-0454-x |
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SPR031014011 |
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| 520 | |a Abstract This study provides a bulk, retrospective analysis of 151 breast and chest wall radiotherapy treatment plans, as a small-scale demonstration of the potential breadth and value of the information that may be obtained from clinical data mining. The treatments were planned at three centres belonging to one organisation over a period of 3 months. All 151 plans were used to evaluate inter-centre consistency and compliance with a local planning protocol. A subset of 79 plans, from one centre, were used in a more detailed evaluation of the effects of anatomical asymmetry on heart and lung dose, the effects of a metallic temporary tissue expander port on dose homogeneity and the overall conformity and homogeneity achieved in routine breast treatment planning. Differences in anatomical structure contouring and nomenclature were identified between the three centres, with all centres showing some non-compliance with the local planning protocol. When evaluated against standard conformity indices, these breast plans performed relatively poorly. However, when evaluated against recommended organ-at-risk tolerances, all evaluated plans performed sufficiently well that tighter planning tolerances could be recommended for future planning. Heart doses calculated in left breast and chest wall treatments were significantly higher than heart doses calculated in right sided breast and chest wall treatments (p < 0.001). In the treatment involving a temporary tissue expander, the inflated implant effectively pushed the targeted breast tissue away from the healthy tissues, leading to a dose distribution that was relatively conformal, although attenuation through the tissue expander’s metallic port may have been underestimated by the treatment planning system. The results of this study exemplify the use of bulk treatment planning data to evaluate clinical workloads and inform ongoing treatment planning. | ||
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| 700 | 1 | |a Langton, C. M. |4 aut | |
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10.1007/s13246-016-0454-x doi (DE-627)SPR031014011 (SPR)s13246-016-0454-x-e DE-627 ger DE-627 rakwb eng Kairn, T. verfasserin aut Bulk evaluation and comparison of radiotherapy treatment plans for breast cancer 2016 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier © Australasian College of Physical Scientists and Engineers in Medicine 2016 Abstract This study provides a bulk, retrospective analysis of 151 breast and chest wall radiotherapy treatment plans, as a small-scale demonstration of the potential breadth and value of the information that may be obtained from clinical data mining. The treatments were planned at three centres belonging to one organisation over a period of 3 months. All 151 plans were used to evaluate inter-centre consistency and compliance with a local planning protocol. A subset of 79 plans, from one centre, were used in a more detailed evaluation of the effects of anatomical asymmetry on heart and lung dose, the effects of a metallic temporary tissue expander port on dose homogeneity and the overall conformity and homogeneity achieved in routine breast treatment planning. Differences in anatomical structure contouring and nomenclature were identified between the three centres, with all centres showing some non-compliance with the local planning protocol. When evaluated against standard conformity indices, these breast plans performed relatively poorly. However, when evaluated against recommended organ-at-risk tolerances, all evaluated plans performed sufficiently well that tighter planning tolerances could be recommended for future planning. Heart doses calculated in left breast and chest wall treatments were significantly higher than heart doses calculated in right sided breast and chest wall treatments (p < 0.001). In the treatment involving a temporary tissue expander, the inflated implant effectively pushed the targeted breast tissue away from the healthy tissues, leading to a dose distribution that was relatively conformal, although attenuation through the tissue expander’s metallic port may have been underestimated by the treatment planning system. The results of this study exemplify the use of bulk treatment planning data to evaluate clinical workloads and inform ongoing treatment planning. Treatment planning (dpeaa)DE-He213 Data mining (dpeaa)DE-He213 Radiation therapy (dpeaa)DE-He213 Crowe, S. B. aut Langton, C. M. aut Trapp, J. V. aut Enthalten in Australasian physical & engineering sciences in medicine Cham : Springer, 2001 39(2016), 3 vom: 20. Juni, Seite 633-644 (DE-627)320430707 (DE-600)2003728-4 1879-5447 nnns volume:39 year:2016 number:3 day:20 month:06 pages:633-644 https://dx.doi.org/10.1007/s13246-016-0454-x lizenzpflichtig Volltext GBV_USEFLAG_A SYSFLAG_A GBV_SPRINGER SSG-OLC-PHA GBV_ILN_11 GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_32 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_70 GBV_ILN_73 GBV_ILN_74 GBV_ILN_90 GBV_ILN_95 GBV_ILN_100 GBV_ILN_101 GBV_ILN_105 GBV_ILN_110 GBV_ILN_120 GBV_ILN_138 GBV_ILN_150 GBV_ILN_151 GBV_ILN_152 GBV_ILN_161 GBV_ILN_170 GBV_ILN_171 GBV_ILN_187 GBV_ILN_213 GBV_ILN_224 GBV_ILN_230 GBV_ILN_250 GBV_ILN_281 GBV_ILN_285 GBV_ILN_293 GBV_ILN_370 GBV_ILN_602 GBV_ILN_636 GBV_ILN_702 GBV_ILN_2001 GBV_ILN_2003 GBV_ILN_2004 GBV_ILN_2005 GBV_ILN_2006 GBV_ILN_2007 GBV_ILN_2008 GBV_ILN_2009 GBV_ILN_2010 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2015 GBV_ILN_2020 GBV_ILN_2021 GBV_ILN_2025 GBV_ILN_2026 GBV_ILN_2027 GBV_ILN_2031 GBV_ILN_2034 GBV_ILN_2037 GBV_ILN_2038 GBV_ILN_2039 GBV_ILN_2044 GBV_ILN_2048 GBV_ILN_2049 GBV_ILN_2050 GBV_ILN_2055 GBV_ILN_2057 GBV_ILN_2059 GBV_ILN_2061 GBV_ILN_2064 GBV_ILN_2065 GBV_ILN_2068 GBV_ILN_2070 GBV_ILN_2088 GBV_ILN_2093 GBV_ILN_2106 GBV_ILN_2107 GBV_ILN_2108 GBV_ILN_2110 GBV_ILN_2111 GBV_ILN_2112 GBV_ILN_2113 GBV_ILN_2116 GBV_ILN_2118 GBV_ILN_2119 GBV_ILN_2122 GBV_ILN_2129 GBV_ILN_2143 GBV_ILN_2144 GBV_ILN_2147 GBV_ILN_2148 GBV_ILN_2152 GBV_ILN_2153 GBV_ILN_2188 GBV_ILN_2190 GBV_ILN_2232 GBV_ILN_2336 GBV_ILN_2446 GBV_ILN_2470 GBV_ILN_2472 GBV_ILN_2507 GBV_ILN_2522 GBV_ILN_2548 GBV_ILN_4035 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4242 GBV_ILN_4246 GBV_ILN_4249 GBV_ILN_4251 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4326 GBV_ILN_4333 GBV_ILN_4334 GBV_ILN_4335 GBV_ILN_4336 GBV_ILN_4338 GBV_ILN_4393 GBV_ILN_4700 AR 39 2016 3 20 06 633-644 |
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10.1007/s13246-016-0454-x doi (DE-627)SPR031014011 (SPR)s13246-016-0454-x-e DE-627 ger DE-627 rakwb eng Kairn, T. verfasserin aut Bulk evaluation and comparison of radiotherapy treatment plans for breast cancer 2016 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier © Australasian College of Physical Scientists and Engineers in Medicine 2016 Abstract This study provides a bulk, retrospective analysis of 151 breast and chest wall radiotherapy treatment plans, as a small-scale demonstration of the potential breadth and value of the information that may be obtained from clinical data mining. The treatments were planned at three centres belonging to one organisation over a period of 3 months. All 151 plans were used to evaluate inter-centre consistency and compliance with a local planning protocol. A subset of 79 plans, from one centre, were used in a more detailed evaluation of the effects of anatomical asymmetry on heart and lung dose, the effects of a metallic temporary tissue expander port on dose homogeneity and the overall conformity and homogeneity achieved in routine breast treatment planning. Differences in anatomical structure contouring and nomenclature were identified between the three centres, with all centres showing some non-compliance with the local planning protocol. When evaluated against standard conformity indices, these breast plans performed relatively poorly. However, when evaluated against recommended organ-at-risk tolerances, all evaluated plans performed sufficiently well that tighter planning tolerances could be recommended for future planning. Heart doses calculated in left breast and chest wall treatments were significantly higher than heart doses calculated in right sided breast and chest wall treatments (p < 0.001). In the treatment involving a temporary tissue expander, the inflated implant effectively pushed the targeted breast tissue away from the healthy tissues, leading to a dose distribution that was relatively conformal, although attenuation through the tissue expander’s metallic port may have been underestimated by the treatment planning system. The results of this study exemplify the use of bulk treatment planning data to evaluate clinical workloads and inform ongoing treatment planning. Treatment planning (dpeaa)DE-He213 Data mining (dpeaa)DE-He213 Radiation therapy (dpeaa)DE-He213 Crowe, S. B. aut Langton, C. M. aut Trapp, J. V. aut Enthalten in Australasian physical & engineering sciences in medicine Cham : Springer, 2001 39(2016), 3 vom: 20. Juni, Seite 633-644 (DE-627)320430707 (DE-600)2003728-4 1879-5447 nnns volume:39 year:2016 number:3 day:20 month:06 pages:633-644 https://dx.doi.org/10.1007/s13246-016-0454-x lizenzpflichtig Volltext GBV_USEFLAG_A SYSFLAG_A GBV_SPRINGER SSG-OLC-PHA GBV_ILN_11 GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_32 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_70 GBV_ILN_73 GBV_ILN_74 GBV_ILN_90 GBV_ILN_95 GBV_ILN_100 GBV_ILN_101 GBV_ILN_105 GBV_ILN_110 GBV_ILN_120 GBV_ILN_138 GBV_ILN_150 GBV_ILN_151 GBV_ILN_152 GBV_ILN_161 GBV_ILN_170 GBV_ILN_171 GBV_ILN_187 GBV_ILN_213 GBV_ILN_224 GBV_ILN_230 GBV_ILN_250 GBV_ILN_281 GBV_ILN_285 GBV_ILN_293 GBV_ILN_370 GBV_ILN_602 GBV_ILN_636 GBV_ILN_702 GBV_ILN_2001 GBV_ILN_2003 GBV_ILN_2004 GBV_ILN_2005 GBV_ILN_2006 GBV_ILN_2007 GBV_ILN_2008 GBV_ILN_2009 GBV_ILN_2010 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2015 GBV_ILN_2020 GBV_ILN_2021 GBV_ILN_2025 GBV_ILN_2026 GBV_ILN_2027 GBV_ILN_2031 GBV_ILN_2034 GBV_ILN_2037 GBV_ILN_2038 GBV_ILN_2039 GBV_ILN_2044 GBV_ILN_2048 GBV_ILN_2049 GBV_ILN_2050 GBV_ILN_2055 GBV_ILN_2057 GBV_ILN_2059 GBV_ILN_2061 GBV_ILN_2064 GBV_ILN_2065 GBV_ILN_2068 GBV_ILN_2070 GBV_ILN_2088 GBV_ILN_2093 GBV_ILN_2106 GBV_ILN_2107 GBV_ILN_2108 GBV_ILN_2110 GBV_ILN_2111 GBV_ILN_2112 GBV_ILN_2113 GBV_ILN_2116 GBV_ILN_2118 GBV_ILN_2119 GBV_ILN_2122 GBV_ILN_2129 GBV_ILN_2143 GBV_ILN_2144 GBV_ILN_2147 GBV_ILN_2148 GBV_ILN_2152 GBV_ILN_2153 GBV_ILN_2188 GBV_ILN_2190 GBV_ILN_2232 GBV_ILN_2336 GBV_ILN_2446 GBV_ILN_2470 GBV_ILN_2472 GBV_ILN_2507 GBV_ILN_2522 GBV_ILN_2548 GBV_ILN_4035 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4242 GBV_ILN_4246 GBV_ILN_4249 GBV_ILN_4251 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4326 GBV_ILN_4333 GBV_ILN_4334 GBV_ILN_4335 GBV_ILN_4336 GBV_ILN_4338 GBV_ILN_4393 GBV_ILN_4700 AR 39 2016 3 20 06 633-644 |
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10.1007/s13246-016-0454-x doi (DE-627)SPR031014011 (SPR)s13246-016-0454-x-e DE-627 ger DE-627 rakwb eng Kairn, T. verfasserin aut Bulk evaluation and comparison of radiotherapy treatment plans for breast cancer 2016 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier © Australasian College of Physical Scientists and Engineers in Medicine 2016 Abstract This study provides a bulk, retrospective analysis of 151 breast and chest wall radiotherapy treatment plans, as a small-scale demonstration of the potential breadth and value of the information that may be obtained from clinical data mining. The treatments were planned at three centres belonging to one organisation over a period of 3 months. All 151 plans were used to evaluate inter-centre consistency and compliance with a local planning protocol. A subset of 79 plans, from one centre, were used in a more detailed evaluation of the effects of anatomical asymmetry on heart and lung dose, the effects of a metallic temporary tissue expander port on dose homogeneity and the overall conformity and homogeneity achieved in routine breast treatment planning. Differences in anatomical structure contouring and nomenclature were identified between the three centres, with all centres showing some non-compliance with the local planning protocol. When evaluated against standard conformity indices, these breast plans performed relatively poorly. However, when evaluated against recommended organ-at-risk tolerances, all evaluated plans performed sufficiently well that tighter planning tolerances could be recommended for future planning. Heart doses calculated in left breast and chest wall treatments were significantly higher than heart doses calculated in right sided breast and chest wall treatments (p < 0.001). In the treatment involving a temporary tissue expander, the inflated implant effectively pushed the targeted breast tissue away from the healthy tissues, leading to a dose distribution that was relatively conformal, although attenuation through the tissue expander’s metallic port may have been underestimated by the treatment planning system. The results of this study exemplify the use of bulk treatment planning data to evaluate clinical workloads and inform ongoing treatment planning. Treatment planning (dpeaa)DE-He213 Data mining (dpeaa)DE-He213 Radiation therapy (dpeaa)DE-He213 Crowe, S. B. aut Langton, C. M. aut Trapp, J. V. aut Enthalten in Australasian physical & engineering sciences in medicine Cham : Springer, 2001 39(2016), 3 vom: 20. Juni, Seite 633-644 (DE-627)320430707 (DE-600)2003728-4 1879-5447 nnns volume:39 year:2016 number:3 day:20 month:06 pages:633-644 https://dx.doi.org/10.1007/s13246-016-0454-x lizenzpflichtig Volltext GBV_USEFLAG_A SYSFLAG_A GBV_SPRINGER SSG-OLC-PHA GBV_ILN_11 GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_32 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_70 GBV_ILN_73 GBV_ILN_74 GBV_ILN_90 GBV_ILN_95 GBV_ILN_100 GBV_ILN_101 GBV_ILN_105 GBV_ILN_110 GBV_ILN_120 GBV_ILN_138 GBV_ILN_150 GBV_ILN_151 GBV_ILN_152 GBV_ILN_161 GBV_ILN_170 GBV_ILN_171 GBV_ILN_187 GBV_ILN_213 GBV_ILN_224 GBV_ILN_230 GBV_ILN_250 GBV_ILN_281 GBV_ILN_285 GBV_ILN_293 GBV_ILN_370 GBV_ILN_602 GBV_ILN_636 GBV_ILN_702 GBV_ILN_2001 GBV_ILN_2003 GBV_ILN_2004 GBV_ILN_2005 GBV_ILN_2006 GBV_ILN_2007 GBV_ILN_2008 GBV_ILN_2009 GBV_ILN_2010 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2015 GBV_ILN_2020 GBV_ILN_2021 GBV_ILN_2025 GBV_ILN_2026 GBV_ILN_2027 GBV_ILN_2031 GBV_ILN_2034 GBV_ILN_2037 GBV_ILN_2038 GBV_ILN_2039 GBV_ILN_2044 GBV_ILN_2048 GBV_ILN_2049 GBV_ILN_2050 GBV_ILN_2055 GBV_ILN_2057 GBV_ILN_2059 GBV_ILN_2061 GBV_ILN_2064 GBV_ILN_2065 GBV_ILN_2068 GBV_ILN_2070 GBV_ILN_2088 GBV_ILN_2093 GBV_ILN_2106 GBV_ILN_2107 GBV_ILN_2108 GBV_ILN_2110 GBV_ILN_2111 GBV_ILN_2112 GBV_ILN_2113 GBV_ILN_2116 GBV_ILN_2118 GBV_ILN_2119 GBV_ILN_2122 GBV_ILN_2129 GBV_ILN_2143 GBV_ILN_2144 GBV_ILN_2147 GBV_ILN_2148 GBV_ILN_2152 GBV_ILN_2153 GBV_ILN_2188 GBV_ILN_2190 GBV_ILN_2232 GBV_ILN_2336 GBV_ILN_2446 GBV_ILN_2470 GBV_ILN_2472 GBV_ILN_2507 GBV_ILN_2522 GBV_ILN_2548 GBV_ILN_4035 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4242 GBV_ILN_4246 GBV_ILN_4249 GBV_ILN_4251 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4326 GBV_ILN_4333 GBV_ILN_4334 GBV_ILN_4335 GBV_ILN_4336 GBV_ILN_4338 GBV_ILN_4393 GBV_ILN_4700 AR 39 2016 3 20 06 633-644 |
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10.1007/s13246-016-0454-x doi (DE-627)SPR031014011 (SPR)s13246-016-0454-x-e DE-627 ger DE-627 rakwb eng Kairn, T. verfasserin aut Bulk evaluation and comparison of radiotherapy treatment plans for breast cancer 2016 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier © Australasian College of Physical Scientists and Engineers in Medicine 2016 Abstract This study provides a bulk, retrospective analysis of 151 breast and chest wall radiotherapy treatment plans, as a small-scale demonstration of the potential breadth and value of the information that may be obtained from clinical data mining. The treatments were planned at three centres belonging to one organisation over a period of 3 months. All 151 plans were used to evaluate inter-centre consistency and compliance with a local planning protocol. A subset of 79 plans, from one centre, were used in a more detailed evaluation of the effects of anatomical asymmetry on heart and lung dose, the effects of a metallic temporary tissue expander port on dose homogeneity and the overall conformity and homogeneity achieved in routine breast treatment planning. Differences in anatomical structure contouring and nomenclature were identified between the three centres, with all centres showing some non-compliance with the local planning protocol. When evaluated against standard conformity indices, these breast plans performed relatively poorly. However, when evaluated against recommended organ-at-risk tolerances, all evaluated plans performed sufficiently well that tighter planning tolerances could be recommended for future planning. Heart doses calculated in left breast and chest wall treatments were significantly higher than heart doses calculated in right sided breast and chest wall treatments (p < 0.001). In the treatment involving a temporary tissue expander, the inflated implant effectively pushed the targeted breast tissue away from the healthy tissues, leading to a dose distribution that was relatively conformal, although attenuation through the tissue expander’s metallic port may have been underestimated by the treatment planning system. The results of this study exemplify the use of bulk treatment planning data to evaluate clinical workloads and inform ongoing treatment planning. Treatment planning (dpeaa)DE-He213 Data mining (dpeaa)DE-He213 Radiation therapy (dpeaa)DE-He213 Crowe, S. B. aut Langton, C. M. aut Trapp, J. V. aut Enthalten in Australasian physical & engineering sciences in medicine Cham : Springer, 2001 39(2016), 3 vom: 20. Juni, Seite 633-644 (DE-627)320430707 (DE-600)2003728-4 1879-5447 nnns volume:39 year:2016 number:3 day:20 month:06 pages:633-644 https://dx.doi.org/10.1007/s13246-016-0454-x lizenzpflichtig Volltext GBV_USEFLAG_A SYSFLAG_A GBV_SPRINGER SSG-OLC-PHA GBV_ILN_11 GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_32 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_70 GBV_ILN_73 GBV_ILN_74 GBV_ILN_90 GBV_ILN_95 GBV_ILN_100 GBV_ILN_101 GBV_ILN_105 GBV_ILN_110 GBV_ILN_120 GBV_ILN_138 GBV_ILN_150 GBV_ILN_151 GBV_ILN_152 GBV_ILN_161 GBV_ILN_170 GBV_ILN_171 GBV_ILN_187 GBV_ILN_213 GBV_ILN_224 GBV_ILN_230 GBV_ILN_250 GBV_ILN_281 GBV_ILN_285 GBV_ILN_293 GBV_ILN_370 GBV_ILN_602 GBV_ILN_636 GBV_ILN_702 GBV_ILN_2001 GBV_ILN_2003 GBV_ILN_2004 GBV_ILN_2005 GBV_ILN_2006 GBV_ILN_2007 GBV_ILN_2008 GBV_ILN_2009 GBV_ILN_2010 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2015 GBV_ILN_2020 GBV_ILN_2021 GBV_ILN_2025 GBV_ILN_2026 GBV_ILN_2027 GBV_ILN_2031 GBV_ILN_2034 GBV_ILN_2037 GBV_ILN_2038 GBV_ILN_2039 GBV_ILN_2044 GBV_ILN_2048 GBV_ILN_2049 GBV_ILN_2050 GBV_ILN_2055 GBV_ILN_2057 GBV_ILN_2059 GBV_ILN_2061 GBV_ILN_2064 GBV_ILN_2065 GBV_ILN_2068 GBV_ILN_2070 GBV_ILN_2088 GBV_ILN_2093 GBV_ILN_2106 GBV_ILN_2107 GBV_ILN_2108 GBV_ILN_2110 GBV_ILN_2111 GBV_ILN_2112 GBV_ILN_2113 GBV_ILN_2116 GBV_ILN_2118 GBV_ILN_2119 GBV_ILN_2122 GBV_ILN_2129 GBV_ILN_2143 GBV_ILN_2144 GBV_ILN_2147 GBV_ILN_2148 GBV_ILN_2152 GBV_ILN_2153 GBV_ILN_2188 GBV_ILN_2190 GBV_ILN_2232 GBV_ILN_2336 GBV_ILN_2446 GBV_ILN_2470 GBV_ILN_2472 GBV_ILN_2507 GBV_ILN_2522 GBV_ILN_2548 GBV_ILN_4035 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4242 GBV_ILN_4246 GBV_ILN_4249 GBV_ILN_4251 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4326 GBV_ILN_4333 GBV_ILN_4334 GBV_ILN_4335 GBV_ILN_4336 GBV_ILN_4338 GBV_ILN_4393 GBV_ILN_4700 AR 39 2016 3 20 06 633-644 |
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10.1007/s13246-016-0454-x doi (DE-627)SPR031014011 (SPR)s13246-016-0454-x-e DE-627 ger DE-627 rakwb eng Kairn, T. verfasserin aut Bulk evaluation and comparison of radiotherapy treatment plans for breast cancer 2016 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier © Australasian College of Physical Scientists and Engineers in Medicine 2016 Abstract This study provides a bulk, retrospective analysis of 151 breast and chest wall radiotherapy treatment plans, as a small-scale demonstration of the potential breadth and value of the information that may be obtained from clinical data mining. The treatments were planned at three centres belonging to one organisation over a period of 3 months. All 151 plans were used to evaluate inter-centre consistency and compliance with a local planning protocol. A subset of 79 plans, from one centre, were used in a more detailed evaluation of the effects of anatomical asymmetry on heart and lung dose, the effects of a metallic temporary tissue expander port on dose homogeneity and the overall conformity and homogeneity achieved in routine breast treatment planning. Differences in anatomical structure contouring and nomenclature were identified between the three centres, with all centres showing some non-compliance with the local planning protocol. When evaluated against standard conformity indices, these breast plans performed relatively poorly. However, when evaluated against recommended organ-at-risk tolerances, all evaluated plans performed sufficiently well that tighter planning tolerances could be recommended for future planning. Heart doses calculated in left breast and chest wall treatments were significantly higher than heart doses calculated in right sided breast and chest wall treatments (p < 0.001). In the treatment involving a temporary tissue expander, the inflated implant effectively pushed the targeted breast tissue away from the healthy tissues, leading to a dose distribution that was relatively conformal, although attenuation through the tissue expander’s metallic port may have been underestimated by the treatment planning system. The results of this study exemplify the use of bulk treatment planning data to evaluate clinical workloads and inform ongoing treatment planning. Treatment planning (dpeaa)DE-He213 Data mining (dpeaa)DE-He213 Radiation therapy (dpeaa)DE-He213 Crowe, S. B. aut Langton, C. M. aut Trapp, J. V. aut Enthalten in Australasian physical & engineering sciences in medicine Cham : Springer, 2001 39(2016), 3 vom: 20. Juni, Seite 633-644 (DE-627)320430707 (DE-600)2003728-4 1879-5447 nnns volume:39 year:2016 number:3 day:20 month:06 pages:633-644 https://dx.doi.org/10.1007/s13246-016-0454-x lizenzpflichtig Volltext GBV_USEFLAG_A SYSFLAG_A GBV_SPRINGER SSG-OLC-PHA GBV_ILN_11 GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_32 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_70 GBV_ILN_73 GBV_ILN_74 GBV_ILN_90 GBV_ILN_95 GBV_ILN_100 GBV_ILN_101 GBV_ILN_105 GBV_ILN_110 GBV_ILN_120 GBV_ILN_138 GBV_ILN_150 GBV_ILN_151 GBV_ILN_152 GBV_ILN_161 GBV_ILN_170 GBV_ILN_171 GBV_ILN_187 GBV_ILN_213 GBV_ILN_224 GBV_ILN_230 GBV_ILN_250 GBV_ILN_281 GBV_ILN_285 GBV_ILN_293 GBV_ILN_370 GBV_ILN_602 GBV_ILN_636 GBV_ILN_702 GBV_ILN_2001 GBV_ILN_2003 GBV_ILN_2004 GBV_ILN_2005 GBV_ILN_2006 GBV_ILN_2007 GBV_ILN_2008 GBV_ILN_2009 GBV_ILN_2010 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2015 GBV_ILN_2020 GBV_ILN_2021 GBV_ILN_2025 GBV_ILN_2026 GBV_ILN_2027 GBV_ILN_2031 GBV_ILN_2034 GBV_ILN_2037 GBV_ILN_2038 GBV_ILN_2039 GBV_ILN_2044 GBV_ILN_2048 GBV_ILN_2049 GBV_ILN_2050 GBV_ILN_2055 GBV_ILN_2057 GBV_ILN_2059 GBV_ILN_2061 GBV_ILN_2064 GBV_ILN_2065 GBV_ILN_2068 GBV_ILN_2070 GBV_ILN_2088 GBV_ILN_2093 GBV_ILN_2106 GBV_ILN_2107 GBV_ILN_2108 GBV_ILN_2110 GBV_ILN_2111 GBV_ILN_2112 GBV_ILN_2113 GBV_ILN_2116 GBV_ILN_2118 GBV_ILN_2119 GBV_ILN_2122 GBV_ILN_2129 GBV_ILN_2143 GBV_ILN_2144 GBV_ILN_2147 GBV_ILN_2148 GBV_ILN_2152 GBV_ILN_2153 GBV_ILN_2188 GBV_ILN_2190 GBV_ILN_2232 GBV_ILN_2336 GBV_ILN_2446 GBV_ILN_2470 GBV_ILN_2472 GBV_ILN_2507 GBV_ILN_2522 GBV_ILN_2548 GBV_ILN_4035 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4242 GBV_ILN_4246 GBV_ILN_4249 GBV_ILN_4251 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4326 GBV_ILN_4333 GBV_ILN_4334 GBV_ILN_4335 GBV_ILN_4336 GBV_ILN_4338 GBV_ILN_4393 GBV_ILN_4700 AR 39 2016 3 20 06 633-644 |
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Kairn, T. |
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Kairn, T. misc Treatment planning misc Data mining misc Radiation therapy Bulk evaluation and comparison of radiotherapy treatment plans for breast cancer |
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Bulk evaluation and comparison of radiotherapy treatment plans for breast cancer Treatment planning (dpeaa)DE-He213 Data mining (dpeaa)DE-He213 Radiation therapy (dpeaa)DE-He213 |
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Bulk evaluation and comparison of radiotherapy treatment plans for breast cancer |
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Kairn, T. Crowe, S. B. Langton, C. M. Trapp, J. V. |
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bulk evaluation and comparison of radiotherapy treatment plans for breast cancer |
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Bulk evaluation and comparison of radiotherapy treatment plans for breast cancer |
| abstract |
Abstract This study provides a bulk, retrospective analysis of 151 breast and chest wall radiotherapy treatment plans, as a small-scale demonstration of the potential breadth and value of the information that may be obtained from clinical data mining. The treatments were planned at three centres belonging to one organisation over a period of 3 months. All 151 plans were used to evaluate inter-centre consistency and compliance with a local planning protocol. A subset of 79 plans, from one centre, were used in a more detailed evaluation of the effects of anatomical asymmetry on heart and lung dose, the effects of a metallic temporary tissue expander port on dose homogeneity and the overall conformity and homogeneity achieved in routine breast treatment planning. Differences in anatomical structure contouring and nomenclature were identified between the three centres, with all centres showing some non-compliance with the local planning protocol. When evaluated against standard conformity indices, these breast plans performed relatively poorly. However, when evaluated against recommended organ-at-risk tolerances, all evaluated plans performed sufficiently well that tighter planning tolerances could be recommended for future planning. Heart doses calculated in left breast and chest wall treatments were significantly higher than heart doses calculated in right sided breast and chest wall treatments (p < 0.001). In the treatment involving a temporary tissue expander, the inflated implant effectively pushed the targeted breast tissue away from the healthy tissues, leading to a dose distribution that was relatively conformal, although attenuation through the tissue expander’s metallic port may have been underestimated by the treatment planning system. The results of this study exemplify the use of bulk treatment planning data to evaluate clinical workloads and inform ongoing treatment planning. © Australasian College of Physical Scientists and Engineers in Medicine 2016 |
| abstractGer |
Abstract This study provides a bulk, retrospective analysis of 151 breast and chest wall radiotherapy treatment plans, as a small-scale demonstration of the potential breadth and value of the information that may be obtained from clinical data mining. The treatments were planned at three centres belonging to one organisation over a period of 3 months. All 151 plans were used to evaluate inter-centre consistency and compliance with a local planning protocol. A subset of 79 plans, from one centre, were used in a more detailed evaluation of the effects of anatomical asymmetry on heart and lung dose, the effects of a metallic temporary tissue expander port on dose homogeneity and the overall conformity and homogeneity achieved in routine breast treatment planning. Differences in anatomical structure contouring and nomenclature were identified between the three centres, with all centres showing some non-compliance with the local planning protocol. When evaluated against standard conformity indices, these breast plans performed relatively poorly. However, when evaluated against recommended organ-at-risk tolerances, all evaluated plans performed sufficiently well that tighter planning tolerances could be recommended for future planning. Heart doses calculated in left breast and chest wall treatments were significantly higher than heart doses calculated in right sided breast and chest wall treatments (p < 0.001). In the treatment involving a temporary tissue expander, the inflated implant effectively pushed the targeted breast tissue away from the healthy tissues, leading to a dose distribution that was relatively conformal, although attenuation through the tissue expander’s metallic port may have been underestimated by the treatment planning system. The results of this study exemplify the use of bulk treatment planning data to evaluate clinical workloads and inform ongoing treatment planning. © Australasian College of Physical Scientists and Engineers in Medicine 2016 |
| abstract_unstemmed |
Abstract This study provides a bulk, retrospective analysis of 151 breast and chest wall radiotherapy treatment plans, as a small-scale demonstration of the potential breadth and value of the information that may be obtained from clinical data mining. The treatments were planned at three centres belonging to one organisation over a period of 3 months. All 151 plans were used to evaluate inter-centre consistency and compliance with a local planning protocol. A subset of 79 plans, from one centre, were used in a more detailed evaluation of the effects of anatomical asymmetry on heart and lung dose, the effects of a metallic temporary tissue expander port on dose homogeneity and the overall conformity and homogeneity achieved in routine breast treatment planning. Differences in anatomical structure contouring and nomenclature were identified between the three centres, with all centres showing some non-compliance with the local planning protocol. When evaluated against standard conformity indices, these breast plans performed relatively poorly. However, when evaluated against recommended organ-at-risk tolerances, all evaluated plans performed sufficiently well that tighter planning tolerances could be recommended for future planning. Heart doses calculated in left breast and chest wall treatments were significantly higher than heart doses calculated in right sided breast and chest wall treatments (p < 0.001). In the treatment involving a temporary tissue expander, the inflated implant effectively pushed the targeted breast tissue away from the healthy tissues, leading to a dose distribution that was relatively conformal, although attenuation through the tissue expander’s metallic port may have been underestimated by the treatment planning system. The results of this study exemplify the use of bulk treatment planning data to evaluate clinical workloads and inform ongoing treatment planning. © Australasian College of Physical Scientists and Engineers in Medicine 2016 |
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Bulk evaluation and comparison of radiotherapy treatment plans for breast cancer |
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Crowe, S. B. Langton, C. M. Trapp, J. V. |
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10.1007/s13246-016-0454-x |
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2024-07-03T21:28:58.782Z |
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| score |
7.4020147 |