Anaplasic lymphoma kinase positive inflammatory myofibroblastic tumour with renal pelvic calculus: a case report

Abstract Inflammatory myofibroblastic tumour is a distinctive mesenchymal neoplasm, composed of a variable admixture of myofibroblastic spindle-shaped and inflammatory cells which were originally described in the lung, as a nonneoplastic lesion and designated as an inflammatory pseudotumour. The lac...
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Autor*in:	Elfatemi, Hinde [verfasserIn] Laila, Chbani Znati, Kaoutar Tazi, Mohamed Fadl Ahallal, Youness Tazi, Elmehdi Farih, Moulay Hassan Amarti, Afaf

Format:	E-Artikel
Sprache:	Englisch

Erschienen:	2009

Schlagwörter:	Anaplastic Lymphoma Kinase Actine Smooth Muscle Inflammatory Myofibroblastic Tumour Myofibroblastic Proliferation Total Nephrectomy

Anmerkung:	© licensee BioMed Central Ltd. 2009. This article is published under license to BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (

Übergeordnetes Werk:	Enthalten in: Cases journal - London : Biomed Central, 2008, 2(2009), 1 vom: 21. Aug.
Übergeordnetes Werk:	volume:2 ; year:2009 ; number:1 ; day:21 ; month:08

Links:	Volltext

DOI / URN:	10.4076/1757-1626-2-6373

Katalog-ID:	SPR031089569

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spelling	10.4076/1757-1626-2-6373 doi (DE-627)SPR031089569 (SPR)1757-1626-2-6373-e DE-627 ger DE-627 rakwb eng Elfatemi, Hinde verfasserin aut Anaplasic lymphoma kinase positive inflammatory myofibroblastic tumour with renal pelvic calculus: a case report 2009 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier © licensee BioMed Central Ltd. 2009. This article is published under license to BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License ( Abstract Inflammatory myofibroblastic tumour is a distinctive mesenchymal neoplasm, composed of a variable admixture of myofibroblastic spindle-shaped and inflammatory cells which were originally described in the lung, as a nonneoplastic lesion and designated as an inflammatory pseudotumour. The lack of certainty of the IMTs pathogenesis is reflected in the large number of terms which have been attributed to this lesion. Recent genetic and molecular studies of IMTs have showed chromosomal abnormalities of 2p23 resulting in a rearrangement of the anaplasic lymphoma kinase gene and have also provided evidence for a monoclonal, noeplastic origin for IMT.Occurrence of IMT in the kidney is very rare, and to our knowledge, only 30 such cases have been described in the literature.This report describes an original case of an ALK positive IMT of the kidney associated with renal pelvic calculus which we believe has never been reported. The differential diagnosis of IMTs will also be discussed. Anaplastic Lymphoma Kinase (dpeaa)DE-He213 Actine Smooth Muscle (dpeaa)DE-He213 Inflammatory Myofibroblastic Tumour (dpeaa)DE-He213 Myofibroblastic Proliferation (dpeaa)DE-He213 Total Nephrectomy (dpeaa)DE-He213 Laila, Chbani aut Znati, Kaoutar aut Tazi, Mohamed Fadl aut Ahallal, Youness aut Tazi, Elmehdi aut Farih, Moulay Hassan aut Amarti, Afaf aut Enthalten in Cases journal London : Biomed Central, 2008 2(2009), 1 vom: 21. Aug. (DE-627)569611202 (DE-600)2431132-7 1757-1626 nnns volume:2 year:2009 number:1 day:21 month:08 https://dx.doi.org/10.4076/1757-1626-2-6373 kostenfrei Volltext GBV_USEFLAG_A SYSFLAG_A GBV_SPRINGER SSG-OLC-PHA GBV_ILN_11 GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_2003 GBV_ILN_2014 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 2 2009 1 21 08
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allfieldsSound	10.4076/1757-1626-2-6373 doi (DE-627)SPR031089569 (SPR)1757-1626-2-6373-e DE-627 ger DE-627 rakwb eng Elfatemi, Hinde verfasserin aut Anaplasic lymphoma kinase positive inflammatory myofibroblastic tumour with renal pelvic calculus: a case report 2009 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier © licensee BioMed Central Ltd. 2009. This article is published under license to BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License ( Abstract Inflammatory myofibroblastic tumour is a distinctive mesenchymal neoplasm, composed of a variable admixture of myofibroblastic spindle-shaped and inflammatory cells which were originally described in the lung, as a nonneoplastic lesion and designated as an inflammatory pseudotumour. The lack of certainty of the IMTs pathogenesis is reflected in the large number of terms which have been attributed to this lesion. Recent genetic and molecular studies of IMTs have showed chromosomal abnormalities of 2p23 resulting in a rearrangement of the anaplasic lymphoma kinase gene and have also provided evidence for a monoclonal, noeplastic origin for IMT.Occurrence of IMT in the kidney is very rare, and to our knowledge, only 30 such cases have been described in the literature.This report describes an original case of an ALK positive IMT of the kidney associated with renal pelvic calculus which we believe has never been reported. The differential diagnosis of IMTs will also be discussed. Anaplastic Lymphoma Kinase (dpeaa)DE-He213 Actine Smooth Muscle (dpeaa)DE-He213 Inflammatory Myofibroblastic Tumour (dpeaa)DE-He213 Myofibroblastic Proliferation (dpeaa)DE-He213 Total Nephrectomy (dpeaa)DE-He213 Laila, Chbani aut Znati, Kaoutar aut Tazi, Mohamed Fadl aut Ahallal, Youness aut Tazi, Elmehdi aut Farih, Moulay Hassan aut Amarti, Afaf aut Enthalten in Cases journal London : Biomed Central, 2008 2(2009), 1 vom: 21. Aug. (DE-627)569611202 (DE-600)2431132-7 1757-1626 nnns volume:2 year:2009 number:1 day:21 month:08 https://dx.doi.org/10.4076/1757-1626-2-6373 kostenfrei Volltext GBV_USEFLAG_A SYSFLAG_A GBV_SPRINGER SSG-OLC-PHA GBV_ILN_11 GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_2003 GBV_ILN_2014 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 2 2009 1 21 08
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source	Enthalten in Cases journal 2(2009), 1 vom: 21. Aug. volume:2 year:2009 number:1 day:21 month:08
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topic_facet	Anaplastic Lymphoma Kinase Actine Smooth Muscle Inflammatory Myofibroblastic Tumour Myofibroblastic Proliferation Total Nephrectomy
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container_title	Cases journal
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spellingShingle	Elfatemi, Hinde misc Anaplastic Lymphoma Kinase misc Actine Smooth Muscle misc Inflammatory Myofibroblastic Tumour misc Myofibroblastic Proliferation misc Total Nephrectomy Anaplasic lymphoma kinase positive inflammatory myofibroblastic tumour with renal pelvic calculus: a case report
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topic_title	Anaplasic lymphoma kinase positive inflammatory myofibroblastic tumour with renal pelvic calculus: a case report Anaplastic Lymphoma Kinase (dpeaa)DE-He213 Actine Smooth Muscle (dpeaa)DE-He213 Inflammatory Myofibroblastic Tumour (dpeaa)DE-He213 Myofibroblastic Proliferation (dpeaa)DE-He213 Total Nephrectomy (dpeaa)DE-He213
topic	misc Anaplastic Lymphoma Kinase misc Actine Smooth Muscle misc Inflammatory Myofibroblastic Tumour misc Myofibroblastic Proliferation misc Total Nephrectomy
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title	Anaplasic lymphoma kinase positive inflammatory myofibroblastic tumour with renal pelvic calculus: a case report
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title_full	Anaplasic lymphoma kinase positive inflammatory myofibroblastic tumour with renal pelvic calculus: a case report
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title_sort	anaplasic lymphoma kinase positive inflammatory myofibroblastic tumour with renal pelvic calculus: a case report
title_auth	Anaplasic lymphoma kinase positive inflammatory myofibroblastic tumour with renal pelvic calculus: a case report
abstract	Abstract Inflammatory myofibroblastic tumour is a distinctive mesenchymal neoplasm, composed of a variable admixture of myofibroblastic spindle-shaped and inflammatory cells which were originally described in the lung, as a nonneoplastic lesion and designated as an inflammatory pseudotumour. The lack of certainty of the IMTs pathogenesis is reflected in the large number of terms which have been attributed to this lesion. Recent genetic and molecular studies of IMTs have showed chromosomal abnormalities of 2p23 resulting in a rearrangement of the anaplasic lymphoma kinase gene and have also provided evidence for a monoclonal, noeplastic origin for IMT.Occurrence of IMT in the kidney is very rare, and to our knowledge, only 30 such cases have been described in the literature.This report describes an original case of an ALK positive IMT of the kidney associated with renal pelvic calculus which we believe has never been reported. The differential diagnosis of IMTs will also be discussed. © licensee BioMed Central Ltd. 2009. This article is published under license to BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (
abstractGer	Abstract Inflammatory myofibroblastic tumour is a distinctive mesenchymal neoplasm, composed of a variable admixture of myofibroblastic spindle-shaped and inflammatory cells which were originally described in the lung, as a nonneoplastic lesion and designated as an inflammatory pseudotumour. The lack of certainty of the IMTs pathogenesis is reflected in the large number of terms which have been attributed to this lesion. Recent genetic and molecular studies of IMTs have showed chromosomal abnormalities of 2p23 resulting in a rearrangement of the anaplasic lymphoma kinase gene and have also provided evidence for a monoclonal, noeplastic origin for IMT.Occurrence of IMT in the kidney is very rare, and to our knowledge, only 30 such cases have been described in the literature.This report describes an original case of an ALK positive IMT of the kidney associated with renal pelvic calculus which we believe has never been reported. The differential diagnosis of IMTs will also be discussed. © licensee BioMed Central Ltd. 2009. This article is published under license to BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (
abstract_unstemmed	Abstract Inflammatory myofibroblastic tumour is a distinctive mesenchymal neoplasm, composed of a variable admixture of myofibroblastic spindle-shaped and inflammatory cells which were originally described in the lung, as a nonneoplastic lesion and designated as an inflammatory pseudotumour. The lack of certainty of the IMTs pathogenesis is reflected in the large number of terms which have been attributed to this lesion. Recent genetic and molecular studies of IMTs have showed chromosomal abnormalities of 2p23 resulting in a rearrangement of the anaplasic lymphoma kinase gene and have also provided evidence for a monoclonal, noeplastic origin for IMT.Occurrence of IMT in the kidney is very rare, and to our knowledge, only 30 such cases have been described in the literature.This report describes an original case of an ALK positive IMT of the kidney associated with renal pelvic calculus which we believe has never been reported. The differential diagnosis of IMTs will also be discussed. © licensee BioMed Central Ltd. 2009. This article is published under license to BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (
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title_short	Anaplasic lymphoma kinase positive inflammatory myofibroblastic tumour with renal pelvic calculus: a case report
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Anaplasic lymphoma kinase positive inflammatory myofibroblastic tumour with renal pelvic calculus: a case report

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