Effects of waterborne copper on oxidative stress and immune responses in red seabream, Pagrus major
Backgrounds Copper (Cu) plays an essential role in many enzymatic processes including cellular respiration. In this study, we investigated the oxidative stress and immunity of red seabream, Pagrus major, exposed to different concentrations of $ Cu^{2+} $ (10, 20, 30, and 40 μg/L) for 120 h. Methods...
Ausführliche Beschreibung
Gespeichert in:
| Autor*in: |
Choi, Cheol Young [verfasserIn] |
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| Format: |
E-Artikel |
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| Sprache: |
Englisch |
| Erschienen: |
2018 |
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| Schlagwörter: |
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| Anmerkung: |
© The Korean Society of Toxicogenomics and Toxicoproteomics and Springer Nature B.V. 2018 |
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| Übergeordnetes Werk: |
Enthalten in: Molecular & cellular toxicology - Seoul : Korean Society of Toxicogenomics and Toxicoproteomics, 2005, 14(2018), 3 vom: 23. Juni, Seite 291-301 |
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| Übergeordnetes Werk: |
volume:14 ; year:2018 ; number:3 ; day:23 ; month:06 ; pages:291-301 |
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| DOI / URN: |
10.1007/s13273-018-0032-2 |
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| Katalog-ID: |
SPR031119492 |
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| 100 | 1 | |a Choi, Cheol Young |e verfasserin |4 aut | |
| 245 | 1 | 0 | |a Effects of waterborne copper on oxidative stress and immune responses in red seabream, Pagrus major |
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| 500 | |a © The Korean Society of Toxicogenomics and Toxicoproteomics and Springer Nature B.V. 2018 | ||
| 520 | |a Backgrounds Copper (Cu) plays an essential role in many enzymatic processes including cellular respiration. In this study, we investigated the oxidative stress and immunity of red seabream, Pagrus major, exposed to different concentrations of $ Cu^{2+} $ (10, 20, 30, and 40 μg/L) for 120 h. Methods We measured the expressions of mRNA, activities of antioxidant enzymes superoxide dismutase (SOD) and catalase (CAT), the levels of plasma hydrogen peroxide ($ H_{2} %$ O_{2} $) and lipid peroxide (LPO), and immune parameters lysozyme, immunoglobulin M (IgM), and melatonin. Results The mRNA expressions, activities of antioxidant enzymes, and the levels of plasma $ H_{2} %$ O_{2} $ and LPO were significantly higher after exposure to 30 and 40 μg/L of $ Cu^{2+} $ than after exposure to lower concentrations (0, 10, and 20 μg/L). However, the levels of plasma lysozyme, IgM, and melatonin were significantly lower after exposure to 30 and 40 μg/L of $ Cu^{2+} $. Conclusion These results indicate that $ Cu^{2+} $ concentrations of 30 and 40 μg/L can induce an acute toxic oxidative stress and decrease the immune response in red seabream in aquarium conditions. | ||
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| 700 | 1 | |a Shin, Yoon Sub |4 aut | |
| 700 | 1 | |a Kim, Tae Hwan |4 aut | |
| 700 | 1 | |a Choi, Ji Yong |4 aut | |
| 700 | 1 | |a Kim, Bong-Seok |4 aut | |
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10.1007/s13273-018-0032-2 doi (DE-627)SPR031119492 (SPR)s13273-018-0032-2-e DE-627 ger DE-627 rakwb eng Choi, Cheol Young verfasserin aut Effects of waterborne copper on oxidative stress and immune responses in red seabream, Pagrus major 2018 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier © The Korean Society of Toxicogenomics and Toxicoproteomics and Springer Nature B.V. 2018 Backgrounds Copper (Cu) plays an essential role in many enzymatic processes including cellular respiration. In this study, we investigated the oxidative stress and immunity of red seabream, Pagrus major, exposed to different concentrations of $ Cu^{2+} $ (10, 20, 30, and 40 μg/L) for 120 h. Methods We measured the expressions of mRNA, activities of antioxidant enzymes superoxide dismutase (SOD) and catalase (CAT), the levels of plasma hydrogen peroxide ($ H_{2} %$ O_{2} $) and lipid peroxide (LPO), and immune parameters lysozyme, immunoglobulin M (IgM), and melatonin. Results The mRNA expressions, activities of antioxidant enzymes, and the levels of plasma $ H_{2} %$ O_{2} $ and LPO were significantly higher after exposure to 30 and 40 μg/L of $ Cu^{2+} $ than after exposure to lower concentrations (0, 10, and 20 μg/L). However, the levels of plasma lysozyme, IgM, and melatonin were significantly lower after exposure to 30 and 40 μg/L of $ Cu^{2+} $. Conclusion These results indicate that $ Cu^{2+} $ concentrations of 30 and 40 μg/L can induce an acute toxic oxidative stress and decrease the immune response in red seabream in aquarium conditions. Antioxidant activity (dpeaa)DE-He213 Copper (dpeaa)DE-He213 Immune response (dpeaa)DE-He213 Oxidative stress (dpeaa)DE-He213 Red seabream (dpeaa)DE-He213 Choe, Jong Ryeol aut Shin, Yoon Sub aut Kim, Tae Hwan aut Choi, Ji Yong aut Kim, Bong-Seok aut Enthalten in Molecular & cellular toxicology Seoul : Korean Society of Toxicogenomics and Toxicoproteomics, 2005 14(2018), 3 vom: 23. Juni, Seite 291-301 (DE-627)601532899 (DE-600)2498324-X 2092-8467 nnns volume:14 year:2018 number:3 day:23 month:06 pages:291-301 https://dx.doi.org/10.1007/s13273-018-0032-2 lizenzpflichtig Volltext GBV_USEFLAG_A SYSFLAG_A GBV_SPRINGER SSG-OLC-PHA GBV_ILN_11 GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_32 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_70 GBV_ILN_73 GBV_ILN_74 GBV_ILN_90 GBV_ILN_95 GBV_ILN_100 GBV_ILN_101 GBV_ILN_105 GBV_ILN_110 GBV_ILN_120 GBV_ILN_138 GBV_ILN_150 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_171 GBV_ILN_187 GBV_ILN_213 GBV_ILN_224 GBV_ILN_230 GBV_ILN_250 GBV_ILN_281 GBV_ILN_285 GBV_ILN_293 GBV_ILN_370 GBV_ILN_602 GBV_ILN_636 GBV_ILN_702 GBV_ILN_2001 GBV_ILN_2003 GBV_ILN_2004 GBV_ILN_2005 GBV_ILN_2006 GBV_ILN_2007 GBV_ILN_2008 GBV_ILN_2009 GBV_ILN_2010 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2015 GBV_ILN_2020 GBV_ILN_2021 GBV_ILN_2025 GBV_ILN_2026 GBV_ILN_2027 GBV_ILN_2031 GBV_ILN_2034 GBV_ILN_2037 GBV_ILN_2038 GBV_ILN_2039 GBV_ILN_2044 GBV_ILN_2048 GBV_ILN_2049 GBV_ILN_2050 GBV_ILN_2055 GBV_ILN_2057 GBV_ILN_2059 GBV_ILN_2061 GBV_ILN_2064 GBV_ILN_2065 GBV_ILN_2068 GBV_ILN_2070 GBV_ILN_2086 GBV_ILN_2088 GBV_ILN_2093 GBV_ILN_2106 GBV_ILN_2107 GBV_ILN_2108 GBV_ILN_2110 GBV_ILN_2111 GBV_ILN_2112 GBV_ILN_2113 GBV_ILN_2116 GBV_ILN_2118 GBV_ILN_2119 GBV_ILN_2122 GBV_ILN_2129 GBV_ILN_2143 GBV_ILN_2144 GBV_ILN_2147 GBV_ILN_2148 GBV_ILN_2152 GBV_ILN_2153 GBV_ILN_2188 GBV_ILN_2190 GBV_ILN_2232 GBV_ILN_2336 GBV_ILN_2446 GBV_ILN_2470 GBV_ILN_2472 GBV_ILN_2507 GBV_ILN_2522 GBV_ILN_2548 GBV_ILN_4035 GBV_ILN_4037 GBV_ILN_4046 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4242 GBV_ILN_4246 GBV_ILN_4249 GBV_ILN_4251 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4326 GBV_ILN_4333 GBV_ILN_4334 GBV_ILN_4335 GBV_ILN_4336 GBV_ILN_4338 GBV_ILN_4393 GBV_ILN_4700 AR 14 2018 3 23 06 291-301 |
| spelling |
10.1007/s13273-018-0032-2 doi (DE-627)SPR031119492 (SPR)s13273-018-0032-2-e DE-627 ger DE-627 rakwb eng Choi, Cheol Young verfasserin aut Effects of waterborne copper on oxidative stress and immune responses in red seabream, Pagrus major 2018 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier © The Korean Society of Toxicogenomics and Toxicoproteomics and Springer Nature B.V. 2018 Backgrounds Copper (Cu) plays an essential role in many enzymatic processes including cellular respiration. In this study, we investigated the oxidative stress and immunity of red seabream, Pagrus major, exposed to different concentrations of $ Cu^{2+} $ (10, 20, 30, and 40 μg/L) for 120 h. Methods We measured the expressions of mRNA, activities of antioxidant enzymes superoxide dismutase (SOD) and catalase (CAT), the levels of plasma hydrogen peroxide ($ H_{2} %$ O_{2} $) and lipid peroxide (LPO), and immune parameters lysozyme, immunoglobulin M (IgM), and melatonin. Results The mRNA expressions, activities of antioxidant enzymes, and the levels of plasma $ H_{2} %$ O_{2} $ and LPO were significantly higher after exposure to 30 and 40 μg/L of $ Cu^{2+} $ than after exposure to lower concentrations (0, 10, and 20 μg/L). However, the levels of plasma lysozyme, IgM, and melatonin were significantly lower after exposure to 30 and 40 μg/L of $ Cu^{2+} $. Conclusion These results indicate that $ Cu^{2+} $ concentrations of 30 and 40 μg/L can induce an acute toxic oxidative stress and decrease the immune response in red seabream in aquarium conditions. Antioxidant activity (dpeaa)DE-He213 Copper (dpeaa)DE-He213 Immune response (dpeaa)DE-He213 Oxidative stress (dpeaa)DE-He213 Red seabream (dpeaa)DE-He213 Choe, Jong Ryeol aut Shin, Yoon Sub aut Kim, Tae Hwan aut Choi, Ji Yong aut Kim, Bong-Seok aut Enthalten in Molecular & cellular toxicology Seoul : Korean Society of Toxicogenomics and Toxicoproteomics, 2005 14(2018), 3 vom: 23. Juni, Seite 291-301 (DE-627)601532899 (DE-600)2498324-X 2092-8467 nnns volume:14 year:2018 number:3 day:23 month:06 pages:291-301 https://dx.doi.org/10.1007/s13273-018-0032-2 lizenzpflichtig Volltext GBV_USEFLAG_A SYSFLAG_A GBV_SPRINGER SSG-OLC-PHA GBV_ILN_11 GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_32 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_70 GBV_ILN_73 GBV_ILN_74 GBV_ILN_90 GBV_ILN_95 GBV_ILN_100 GBV_ILN_101 GBV_ILN_105 GBV_ILN_110 GBV_ILN_120 GBV_ILN_138 GBV_ILN_150 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_171 GBV_ILN_187 GBV_ILN_213 GBV_ILN_224 GBV_ILN_230 GBV_ILN_250 GBV_ILN_281 GBV_ILN_285 GBV_ILN_293 GBV_ILN_370 GBV_ILN_602 GBV_ILN_636 GBV_ILN_702 GBV_ILN_2001 GBV_ILN_2003 GBV_ILN_2004 GBV_ILN_2005 GBV_ILN_2006 GBV_ILN_2007 GBV_ILN_2008 GBV_ILN_2009 GBV_ILN_2010 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2015 GBV_ILN_2020 GBV_ILN_2021 GBV_ILN_2025 GBV_ILN_2026 GBV_ILN_2027 GBV_ILN_2031 GBV_ILN_2034 GBV_ILN_2037 GBV_ILN_2038 GBV_ILN_2039 GBV_ILN_2044 GBV_ILN_2048 GBV_ILN_2049 GBV_ILN_2050 GBV_ILN_2055 GBV_ILN_2057 GBV_ILN_2059 GBV_ILN_2061 GBV_ILN_2064 GBV_ILN_2065 GBV_ILN_2068 GBV_ILN_2070 GBV_ILN_2086 GBV_ILN_2088 GBV_ILN_2093 GBV_ILN_2106 GBV_ILN_2107 GBV_ILN_2108 GBV_ILN_2110 GBV_ILN_2111 GBV_ILN_2112 GBV_ILN_2113 GBV_ILN_2116 GBV_ILN_2118 GBV_ILN_2119 GBV_ILN_2122 GBV_ILN_2129 GBV_ILN_2143 GBV_ILN_2144 GBV_ILN_2147 GBV_ILN_2148 GBV_ILN_2152 GBV_ILN_2153 GBV_ILN_2188 GBV_ILN_2190 GBV_ILN_2232 GBV_ILN_2336 GBV_ILN_2446 GBV_ILN_2470 GBV_ILN_2472 GBV_ILN_2507 GBV_ILN_2522 GBV_ILN_2548 GBV_ILN_4035 GBV_ILN_4037 GBV_ILN_4046 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4242 GBV_ILN_4246 GBV_ILN_4249 GBV_ILN_4251 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4326 GBV_ILN_4333 GBV_ILN_4334 GBV_ILN_4335 GBV_ILN_4336 GBV_ILN_4338 GBV_ILN_4393 GBV_ILN_4700 AR 14 2018 3 23 06 291-301 |
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10.1007/s13273-018-0032-2 doi (DE-627)SPR031119492 (SPR)s13273-018-0032-2-e DE-627 ger DE-627 rakwb eng Choi, Cheol Young verfasserin aut Effects of waterborne copper on oxidative stress and immune responses in red seabream, Pagrus major 2018 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier © The Korean Society of Toxicogenomics and Toxicoproteomics and Springer Nature B.V. 2018 Backgrounds Copper (Cu) plays an essential role in many enzymatic processes including cellular respiration. In this study, we investigated the oxidative stress and immunity of red seabream, Pagrus major, exposed to different concentrations of $ Cu^{2+} $ (10, 20, 30, and 40 μg/L) for 120 h. Methods We measured the expressions of mRNA, activities of antioxidant enzymes superoxide dismutase (SOD) and catalase (CAT), the levels of plasma hydrogen peroxide ($ H_{2} %$ O_{2} $) and lipid peroxide (LPO), and immune parameters lysozyme, immunoglobulin M (IgM), and melatonin. Results The mRNA expressions, activities of antioxidant enzymes, and the levels of plasma $ H_{2} %$ O_{2} $ and LPO were significantly higher after exposure to 30 and 40 μg/L of $ Cu^{2+} $ than after exposure to lower concentrations (0, 10, and 20 μg/L). However, the levels of plasma lysozyme, IgM, and melatonin were significantly lower after exposure to 30 and 40 μg/L of $ Cu^{2+} $. Conclusion These results indicate that $ Cu^{2+} $ concentrations of 30 and 40 μg/L can induce an acute toxic oxidative stress and decrease the immune response in red seabream in aquarium conditions. Antioxidant activity (dpeaa)DE-He213 Copper (dpeaa)DE-He213 Immune response (dpeaa)DE-He213 Oxidative stress (dpeaa)DE-He213 Red seabream (dpeaa)DE-He213 Choe, Jong Ryeol aut Shin, Yoon Sub aut Kim, Tae Hwan aut Choi, Ji Yong aut Kim, Bong-Seok aut Enthalten in Molecular & cellular toxicology Seoul : Korean Society of Toxicogenomics and Toxicoproteomics, 2005 14(2018), 3 vom: 23. Juni, Seite 291-301 (DE-627)601532899 (DE-600)2498324-X 2092-8467 nnns volume:14 year:2018 number:3 day:23 month:06 pages:291-301 https://dx.doi.org/10.1007/s13273-018-0032-2 lizenzpflichtig Volltext GBV_USEFLAG_A SYSFLAG_A GBV_SPRINGER SSG-OLC-PHA GBV_ILN_11 GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_32 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_70 GBV_ILN_73 GBV_ILN_74 GBV_ILN_90 GBV_ILN_95 GBV_ILN_100 GBV_ILN_101 GBV_ILN_105 GBV_ILN_110 GBV_ILN_120 GBV_ILN_138 GBV_ILN_150 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_171 GBV_ILN_187 GBV_ILN_213 GBV_ILN_224 GBV_ILN_230 GBV_ILN_250 GBV_ILN_281 GBV_ILN_285 GBV_ILN_293 GBV_ILN_370 GBV_ILN_602 GBV_ILN_636 GBV_ILN_702 GBV_ILN_2001 GBV_ILN_2003 GBV_ILN_2004 GBV_ILN_2005 GBV_ILN_2006 GBV_ILN_2007 GBV_ILN_2008 GBV_ILN_2009 GBV_ILN_2010 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2015 GBV_ILN_2020 GBV_ILN_2021 GBV_ILN_2025 GBV_ILN_2026 GBV_ILN_2027 GBV_ILN_2031 GBV_ILN_2034 GBV_ILN_2037 GBV_ILN_2038 GBV_ILN_2039 GBV_ILN_2044 GBV_ILN_2048 GBV_ILN_2049 GBV_ILN_2050 GBV_ILN_2055 GBV_ILN_2057 GBV_ILN_2059 GBV_ILN_2061 GBV_ILN_2064 GBV_ILN_2065 GBV_ILN_2068 GBV_ILN_2070 GBV_ILN_2086 GBV_ILN_2088 GBV_ILN_2093 GBV_ILN_2106 GBV_ILN_2107 GBV_ILN_2108 GBV_ILN_2110 GBV_ILN_2111 GBV_ILN_2112 GBV_ILN_2113 GBV_ILN_2116 GBV_ILN_2118 GBV_ILN_2119 GBV_ILN_2122 GBV_ILN_2129 GBV_ILN_2143 GBV_ILN_2144 GBV_ILN_2147 GBV_ILN_2148 GBV_ILN_2152 GBV_ILN_2153 GBV_ILN_2188 GBV_ILN_2190 GBV_ILN_2232 GBV_ILN_2336 GBV_ILN_2446 GBV_ILN_2470 GBV_ILN_2472 GBV_ILN_2507 GBV_ILN_2522 GBV_ILN_2548 GBV_ILN_4035 GBV_ILN_4037 GBV_ILN_4046 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4242 GBV_ILN_4246 GBV_ILN_4249 GBV_ILN_4251 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4326 GBV_ILN_4333 GBV_ILN_4334 GBV_ILN_4335 GBV_ILN_4336 GBV_ILN_4338 GBV_ILN_4393 GBV_ILN_4700 AR 14 2018 3 23 06 291-301 |
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10.1007/s13273-018-0032-2 doi (DE-627)SPR031119492 (SPR)s13273-018-0032-2-e DE-627 ger DE-627 rakwb eng Choi, Cheol Young verfasserin aut Effects of waterborne copper on oxidative stress and immune responses in red seabream, Pagrus major 2018 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier © The Korean Society of Toxicogenomics and Toxicoproteomics and Springer Nature B.V. 2018 Backgrounds Copper (Cu) plays an essential role in many enzymatic processes including cellular respiration. In this study, we investigated the oxidative stress and immunity of red seabream, Pagrus major, exposed to different concentrations of $ Cu^{2+} $ (10, 20, 30, and 40 μg/L) for 120 h. Methods We measured the expressions of mRNA, activities of antioxidant enzymes superoxide dismutase (SOD) and catalase (CAT), the levels of plasma hydrogen peroxide ($ H_{2} %$ O_{2} $) and lipid peroxide (LPO), and immune parameters lysozyme, immunoglobulin M (IgM), and melatonin. Results The mRNA expressions, activities of antioxidant enzymes, and the levels of plasma $ H_{2} %$ O_{2} $ and LPO were significantly higher after exposure to 30 and 40 μg/L of $ Cu^{2+} $ than after exposure to lower concentrations (0, 10, and 20 μg/L). However, the levels of plasma lysozyme, IgM, and melatonin were significantly lower after exposure to 30 and 40 μg/L of $ Cu^{2+} $. Conclusion These results indicate that $ Cu^{2+} $ concentrations of 30 and 40 μg/L can induce an acute toxic oxidative stress and decrease the immune response in red seabream in aquarium conditions. Antioxidant activity (dpeaa)DE-He213 Copper (dpeaa)DE-He213 Immune response (dpeaa)DE-He213 Oxidative stress (dpeaa)DE-He213 Red seabream (dpeaa)DE-He213 Choe, Jong Ryeol aut Shin, Yoon Sub aut Kim, Tae Hwan aut Choi, Ji Yong aut Kim, Bong-Seok aut Enthalten in Molecular & cellular toxicology Seoul : Korean Society of Toxicogenomics and Toxicoproteomics, 2005 14(2018), 3 vom: 23. Juni, Seite 291-301 (DE-627)601532899 (DE-600)2498324-X 2092-8467 nnns volume:14 year:2018 number:3 day:23 month:06 pages:291-301 https://dx.doi.org/10.1007/s13273-018-0032-2 lizenzpflichtig Volltext GBV_USEFLAG_A SYSFLAG_A GBV_SPRINGER SSG-OLC-PHA GBV_ILN_11 GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_32 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_70 GBV_ILN_73 GBV_ILN_74 GBV_ILN_90 GBV_ILN_95 GBV_ILN_100 GBV_ILN_101 GBV_ILN_105 GBV_ILN_110 GBV_ILN_120 GBV_ILN_138 GBV_ILN_150 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_171 GBV_ILN_187 GBV_ILN_213 GBV_ILN_224 GBV_ILN_230 GBV_ILN_250 GBV_ILN_281 GBV_ILN_285 GBV_ILN_293 GBV_ILN_370 GBV_ILN_602 GBV_ILN_636 GBV_ILN_702 GBV_ILN_2001 GBV_ILN_2003 GBV_ILN_2004 GBV_ILN_2005 GBV_ILN_2006 GBV_ILN_2007 GBV_ILN_2008 GBV_ILN_2009 GBV_ILN_2010 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2015 GBV_ILN_2020 GBV_ILN_2021 GBV_ILN_2025 GBV_ILN_2026 GBV_ILN_2027 GBV_ILN_2031 GBV_ILN_2034 GBV_ILN_2037 GBV_ILN_2038 GBV_ILN_2039 GBV_ILN_2044 GBV_ILN_2048 GBV_ILN_2049 GBV_ILN_2050 GBV_ILN_2055 GBV_ILN_2057 GBV_ILN_2059 GBV_ILN_2061 GBV_ILN_2064 GBV_ILN_2065 GBV_ILN_2068 GBV_ILN_2070 GBV_ILN_2086 GBV_ILN_2088 GBV_ILN_2093 GBV_ILN_2106 GBV_ILN_2107 GBV_ILN_2108 GBV_ILN_2110 GBV_ILN_2111 GBV_ILN_2112 GBV_ILN_2113 GBV_ILN_2116 GBV_ILN_2118 GBV_ILN_2119 GBV_ILN_2122 GBV_ILN_2129 GBV_ILN_2143 GBV_ILN_2144 GBV_ILN_2147 GBV_ILN_2148 GBV_ILN_2152 GBV_ILN_2153 GBV_ILN_2188 GBV_ILN_2190 GBV_ILN_2232 GBV_ILN_2336 GBV_ILN_2446 GBV_ILN_2470 GBV_ILN_2472 GBV_ILN_2507 GBV_ILN_2522 GBV_ILN_2548 GBV_ILN_4035 GBV_ILN_4037 GBV_ILN_4046 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4242 GBV_ILN_4246 GBV_ILN_4249 GBV_ILN_4251 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4326 GBV_ILN_4333 GBV_ILN_4334 GBV_ILN_4335 GBV_ILN_4336 GBV_ILN_4338 GBV_ILN_4393 GBV_ILN_4700 AR 14 2018 3 23 06 291-301 |
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10.1007/s13273-018-0032-2 doi (DE-627)SPR031119492 (SPR)s13273-018-0032-2-e DE-627 ger DE-627 rakwb eng Choi, Cheol Young verfasserin aut Effects of waterborne copper on oxidative stress and immune responses in red seabream, Pagrus major 2018 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier © The Korean Society of Toxicogenomics and Toxicoproteomics and Springer Nature B.V. 2018 Backgrounds Copper (Cu) plays an essential role in many enzymatic processes including cellular respiration. In this study, we investigated the oxidative stress and immunity of red seabream, Pagrus major, exposed to different concentrations of $ Cu^{2+} $ (10, 20, 30, and 40 μg/L) for 120 h. Methods We measured the expressions of mRNA, activities of antioxidant enzymes superoxide dismutase (SOD) and catalase (CAT), the levels of plasma hydrogen peroxide ($ H_{2} %$ O_{2} $) and lipid peroxide (LPO), and immune parameters lysozyme, immunoglobulin M (IgM), and melatonin. Results The mRNA expressions, activities of antioxidant enzymes, and the levels of plasma $ H_{2} %$ O_{2} $ and LPO were significantly higher after exposure to 30 and 40 μg/L of $ Cu^{2+} $ than after exposure to lower concentrations (0, 10, and 20 μg/L). However, the levels of plasma lysozyme, IgM, and melatonin were significantly lower after exposure to 30 and 40 μg/L of $ Cu^{2+} $. Conclusion These results indicate that $ Cu^{2+} $ concentrations of 30 and 40 μg/L can induce an acute toxic oxidative stress and decrease the immune response in red seabream in aquarium conditions. Antioxidant activity (dpeaa)DE-He213 Copper (dpeaa)DE-He213 Immune response (dpeaa)DE-He213 Oxidative stress (dpeaa)DE-He213 Red seabream (dpeaa)DE-He213 Choe, Jong Ryeol aut Shin, Yoon Sub aut Kim, Tae Hwan aut Choi, Ji Yong aut Kim, Bong-Seok aut Enthalten in Molecular & cellular toxicology Seoul : Korean Society of Toxicogenomics and Toxicoproteomics, 2005 14(2018), 3 vom: 23. Juni, Seite 291-301 (DE-627)601532899 (DE-600)2498324-X 2092-8467 nnns volume:14 year:2018 number:3 day:23 month:06 pages:291-301 https://dx.doi.org/10.1007/s13273-018-0032-2 lizenzpflichtig Volltext GBV_USEFLAG_A SYSFLAG_A GBV_SPRINGER SSG-OLC-PHA GBV_ILN_11 GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_32 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_70 GBV_ILN_73 GBV_ILN_74 GBV_ILN_90 GBV_ILN_95 GBV_ILN_100 GBV_ILN_101 GBV_ILN_105 GBV_ILN_110 GBV_ILN_120 GBV_ILN_138 GBV_ILN_150 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_171 GBV_ILN_187 GBV_ILN_213 GBV_ILN_224 GBV_ILN_230 GBV_ILN_250 GBV_ILN_281 GBV_ILN_285 GBV_ILN_293 GBV_ILN_370 GBV_ILN_602 GBV_ILN_636 GBV_ILN_702 GBV_ILN_2001 GBV_ILN_2003 GBV_ILN_2004 GBV_ILN_2005 GBV_ILN_2006 GBV_ILN_2007 GBV_ILN_2008 GBV_ILN_2009 GBV_ILN_2010 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2015 GBV_ILN_2020 GBV_ILN_2021 GBV_ILN_2025 GBV_ILN_2026 GBV_ILN_2027 GBV_ILN_2031 GBV_ILN_2034 GBV_ILN_2037 GBV_ILN_2038 GBV_ILN_2039 GBV_ILN_2044 GBV_ILN_2048 GBV_ILN_2049 GBV_ILN_2050 GBV_ILN_2055 GBV_ILN_2057 GBV_ILN_2059 GBV_ILN_2061 GBV_ILN_2064 GBV_ILN_2065 GBV_ILN_2068 GBV_ILN_2070 GBV_ILN_2086 GBV_ILN_2088 GBV_ILN_2093 GBV_ILN_2106 GBV_ILN_2107 GBV_ILN_2108 GBV_ILN_2110 GBV_ILN_2111 GBV_ILN_2112 GBV_ILN_2113 GBV_ILN_2116 GBV_ILN_2118 GBV_ILN_2119 GBV_ILN_2122 GBV_ILN_2129 GBV_ILN_2143 GBV_ILN_2144 GBV_ILN_2147 GBV_ILN_2148 GBV_ILN_2152 GBV_ILN_2153 GBV_ILN_2188 GBV_ILN_2190 GBV_ILN_2232 GBV_ILN_2336 GBV_ILN_2446 GBV_ILN_2470 GBV_ILN_2472 GBV_ILN_2507 GBV_ILN_2522 GBV_ILN_2548 GBV_ILN_4035 GBV_ILN_4037 GBV_ILN_4046 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4242 GBV_ILN_4246 GBV_ILN_4249 GBV_ILN_4251 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4326 GBV_ILN_4333 GBV_ILN_4334 GBV_ILN_4335 GBV_ILN_4336 GBV_ILN_4338 GBV_ILN_4393 GBV_ILN_4700 AR 14 2018 3 23 06 291-301 |
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Enthalten in Molecular & cellular toxicology 14(2018), 3 vom: 23. Juni, Seite 291-301 volume:14 year:2018 number:3 day:23 month:06 pages:291-301 |
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Enthalten in Molecular & cellular toxicology 14(2018), 3 vom: 23. Juni, Seite 291-301 volume:14 year:2018 number:3 day:23 month:06 pages:291-301 |
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Choi, Cheol Young @@aut@@ Choe, Jong Ryeol @@aut@@ Shin, Yoon Sub @@aut@@ Kim, Tae Hwan @@aut@@ Choi, Ji Yong @@aut@@ Kim, Bong-Seok @@aut@@ |
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<?xml version="1.0" encoding="UTF-8"?><collection xmlns="http://www.loc.gov/MARC21/slim"><record><leader>01000caa a22002652 4500</leader><controlfield tag="001">SPR031119492</controlfield><controlfield tag="003">DE-627</controlfield><controlfield tag="005">20230520001803.0</controlfield><controlfield tag="007">cr uuu---uuuuu</controlfield><controlfield tag="008">201007s2018 xx |||||o 00| ||eng c</controlfield><datafield tag="024" ind1="7" ind2=" "><subfield code="a">10.1007/s13273-018-0032-2</subfield><subfield code="2">doi</subfield></datafield><datafield tag="035" ind1=" " ind2=" "><subfield code="a">(DE-627)SPR031119492</subfield></datafield><datafield tag="035" ind1=" " ind2=" "><subfield code="a">(SPR)s13273-018-0032-2-e</subfield></datafield><datafield tag="040" ind1=" " ind2=" "><subfield code="a">DE-627</subfield><subfield code="b">ger</subfield><subfield code="c">DE-627</subfield><subfield code="e">rakwb</subfield></datafield><datafield tag="041" ind1=" " ind2=" "><subfield code="a">eng</subfield></datafield><datafield tag="100" ind1="1" ind2=" "><subfield code="a">Choi, Cheol Young</subfield><subfield code="e">verfasserin</subfield><subfield code="4">aut</subfield></datafield><datafield tag="245" ind1="1" ind2="0"><subfield code="a">Effects of waterborne copper on oxidative stress and immune responses in red seabream, Pagrus major</subfield></datafield><datafield tag="264" ind1=" " ind2="1"><subfield code="c">2018</subfield></datafield><datafield tag="336" ind1=" " ind2=" "><subfield code="a">Text</subfield><subfield code="b">txt</subfield><subfield code="2">rdacontent</subfield></datafield><datafield tag="337" ind1=" " ind2=" "><subfield code="a">Computermedien</subfield><subfield code="b">c</subfield><subfield code="2">rdamedia</subfield></datafield><datafield tag="338" ind1=" " ind2=" "><subfield code="a">Online-Ressource</subfield><subfield code="b">cr</subfield><subfield code="2">rdacarrier</subfield></datafield><datafield tag="500" ind1=" " ind2=" "><subfield code="a">© The Korean Society of Toxicogenomics and Toxicoproteomics and Springer Nature B.V. 2018</subfield></datafield><datafield tag="520" ind1=" " ind2=" "><subfield code="a">Backgrounds Copper (Cu) plays an essential role in many enzymatic processes including cellular respiration. In this study, we investigated the oxidative stress and immunity of red seabream, Pagrus major, exposed to different concentrations of $ Cu^{2+} $ (10, 20, 30, and 40 μg/L) for 120 h. Methods We measured the expressions of mRNA, activities of antioxidant enzymes superoxide dismutase (SOD) and catalase (CAT), the levels of plasma hydrogen peroxide ($ H_{2} %$ O_{2} $) and lipid peroxide (LPO), and immune parameters lysozyme, immunoglobulin M (IgM), and melatonin. Results The mRNA expressions, activities of antioxidant enzymes, and the levels of plasma $ H_{2} %$ O_{2} $ and LPO were significantly higher after exposure to 30 and 40 μg/L of $ Cu^{2+} $ than after exposure to lower concentrations (0, 10, and 20 μg/L). However, the levels of plasma lysozyme, IgM, and melatonin were significantly lower after exposure to 30 and 40 μg/L of $ Cu^{2+} $. Conclusion These results indicate that $ Cu^{2+} $ concentrations of 30 and 40 μg/L can induce an acute toxic oxidative stress and decrease the immune response in red seabream in aquarium conditions.</subfield></datafield><datafield tag="650" ind1=" " ind2="4"><subfield code="a">Antioxidant activity</subfield><subfield code="7">(dpeaa)DE-He213</subfield></datafield><datafield tag="650" ind1=" " ind2="4"><subfield code="a">Copper</subfield><subfield code="7">(dpeaa)DE-He213</subfield></datafield><datafield tag="650" ind1=" " ind2="4"><subfield code="a">Immune response</subfield><subfield code="7">(dpeaa)DE-He213</subfield></datafield><datafield tag="650" ind1=" " ind2="4"><subfield code="a">Oxidative stress</subfield><subfield code="7">(dpeaa)DE-He213</subfield></datafield><datafield tag="650" ind1=" " ind2="4"><subfield code="a">Red seabream</subfield><subfield code="7">(dpeaa)DE-He213</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Choe, Jong Ryeol</subfield><subfield code="4">aut</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Shin, Yoon Sub</subfield><subfield code="4">aut</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Kim, Tae Hwan</subfield><subfield code="4">aut</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Choi, Ji Yong</subfield><subfield code="4">aut</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Kim, Bong-Seok</subfield><subfield code="4">aut</subfield></datafield><datafield tag="773" ind1="0" ind2="8"><subfield code="i">Enthalten in</subfield><subfield code="t">Molecular & cellular toxicology</subfield><subfield code="d">Seoul : Korean Society of Toxicogenomics and Toxicoproteomics, 2005</subfield><subfield code="g">14(2018), 3 vom: 23. 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Choi, Cheol Young |
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Choi, Cheol Young misc Antioxidant activity misc Copper misc Immune response misc Oxidative stress misc Red seabream Effects of waterborne copper on oxidative stress and immune responses in red seabream, Pagrus major |
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Effects of waterborne copper on oxidative stress and immune responses in red seabream, Pagrus major Antioxidant activity (dpeaa)DE-He213 Copper (dpeaa)DE-He213 Immune response (dpeaa)DE-He213 Oxidative stress (dpeaa)DE-He213 Red seabream (dpeaa)DE-He213 |
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Effects of waterborne copper on oxidative stress and immune responses in red seabream, Pagrus major |
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Effects of waterborne copper on oxidative stress and immune responses in red seabream, Pagrus major |
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Choi, Cheol Young Choe, Jong Ryeol Shin, Yoon Sub Kim, Tae Hwan Choi, Ji Yong Kim, Bong-Seok |
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10.1007/s13273-018-0032-2 |
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effects of waterborne copper on oxidative stress and immune responses in red seabream, pagrus major |
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Effects of waterborne copper on oxidative stress and immune responses in red seabream, Pagrus major |
| abstract |
Backgrounds Copper (Cu) plays an essential role in many enzymatic processes including cellular respiration. In this study, we investigated the oxidative stress and immunity of red seabream, Pagrus major, exposed to different concentrations of $ Cu^{2+} $ (10, 20, 30, and 40 μg/L) for 120 h. Methods We measured the expressions of mRNA, activities of antioxidant enzymes superoxide dismutase (SOD) and catalase (CAT), the levels of plasma hydrogen peroxide ($ H_{2} %$ O_{2} $) and lipid peroxide (LPO), and immune parameters lysozyme, immunoglobulin M (IgM), and melatonin. Results The mRNA expressions, activities of antioxidant enzymes, and the levels of plasma $ H_{2} %$ O_{2} $ and LPO were significantly higher after exposure to 30 and 40 μg/L of $ Cu^{2+} $ than after exposure to lower concentrations (0, 10, and 20 μg/L). However, the levels of plasma lysozyme, IgM, and melatonin were significantly lower after exposure to 30 and 40 μg/L of $ Cu^{2+} $. Conclusion These results indicate that $ Cu^{2+} $ concentrations of 30 and 40 μg/L can induce an acute toxic oxidative stress and decrease the immune response in red seabream in aquarium conditions. © The Korean Society of Toxicogenomics and Toxicoproteomics and Springer Nature B.V. 2018 |
| abstractGer |
Backgrounds Copper (Cu) plays an essential role in many enzymatic processes including cellular respiration. In this study, we investigated the oxidative stress and immunity of red seabream, Pagrus major, exposed to different concentrations of $ Cu^{2+} $ (10, 20, 30, and 40 μg/L) for 120 h. Methods We measured the expressions of mRNA, activities of antioxidant enzymes superoxide dismutase (SOD) and catalase (CAT), the levels of plasma hydrogen peroxide ($ H_{2} %$ O_{2} $) and lipid peroxide (LPO), and immune parameters lysozyme, immunoglobulin M (IgM), and melatonin. Results The mRNA expressions, activities of antioxidant enzymes, and the levels of plasma $ H_{2} %$ O_{2} $ and LPO were significantly higher after exposure to 30 and 40 μg/L of $ Cu^{2+} $ than after exposure to lower concentrations (0, 10, and 20 μg/L). However, the levels of plasma lysozyme, IgM, and melatonin were significantly lower after exposure to 30 and 40 μg/L of $ Cu^{2+} $. Conclusion These results indicate that $ Cu^{2+} $ concentrations of 30 and 40 μg/L can induce an acute toxic oxidative stress and decrease the immune response in red seabream in aquarium conditions. © The Korean Society of Toxicogenomics and Toxicoproteomics and Springer Nature B.V. 2018 |
| abstract_unstemmed |
Backgrounds Copper (Cu) plays an essential role in many enzymatic processes including cellular respiration. In this study, we investigated the oxidative stress and immunity of red seabream, Pagrus major, exposed to different concentrations of $ Cu^{2+} $ (10, 20, 30, and 40 μg/L) for 120 h. Methods We measured the expressions of mRNA, activities of antioxidant enzymes superoxide dismutase (SOD) and catalase (CAT), the levels of plasma hydrogen peroxide ($ H_{2} %$ O_{2} $) and lipid peroxide (LPO), and immune parameters lysozyme, immunoglobulin M (IgM), and melatonin. Results The mRNA expressions, activities of antioxidant enzymes, and the levels of plasma $ H_{2} %$ O_{2} $ and LPO were significantly higher after exposure to 30 and 40 μg/L of $ Cu^{2+} $ than after exposure to lower concentrations (0, 10, and 20 μg/L). However, the levels of plasma lysozyme, IgM, and melatonin were significantly lower after exposure to 30 and 40 μg/L of $ Cu^{2+} $. Conclusion These results indicate that $ Cu^{2+} $ concentrations of 30 and 40 μg/L can induce an acute toxic oxidative stress and decrease the immune response in red seabream in aquarium conditions. © The Korean Society of Toxicogenomics and Toxicoproteomics and Springer Nature B.V. 2018 |
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Effects of waterborne copper on oxidative stress and immune responses in red seabream, Pagrus major |
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Choe, Jong Ryeol Shin, Yoon Sub Kim, Tae Hwan Choi, Ji Yong Kim, Bong-Seok |
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| score |
7.4006443 |