Behavioral Strategies to Lower Postprandial Glucose in Those with Type 2 Diabetes May Also Lower Risk of Coronary Heart Disease

Introduction Efforts to lower glycosylated hemoglobin (A1c) in patients with type 2 diabetes (T2D) are intended to reduce the risk of diabetic complications, but A1c is not the only factor contributing to this risk. Consequently, we re-analyzed published data from a broad-spectrum lifestyle interven...
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Autor*in:	Cox, Daniel J. [verfasserIn] Fang, Kun [verfasserIn] McCall, Anthony L. [verfasserIn] Conaway, Mark R. [verfasserIn] Banton, Tom A. [verfasserIn] Moncrief, Matthew A. [verfasserIn] Diamond, Anne M. [verfasserIn] Taylor, Ann G. [verfasserIn]

Format:	E-Artikel
Sprache:	Englisch

Erschienen:	2018

Schlagwörter:	Behavioral medicine Coronary disease Postprandial hyperglycemia Type 2 diabetes mellitus

Anmerkung:	© The Author(s) 2018

Übergeordnetes Werk:	Enthalten in: Diabetes therapy - Springer Healthcare, 2010, 10(2018), 1 vom: 18. Dez., Seite 277-281
Übergeordnetes Werk:	volume:10 ; year:2018 ; number:1 ; day:18 ; month:12 ; pages:277-281

Links:	Volltext

DOI / URN:	10.1007/s13300-018-0554-6

Katalog-ID:	SPR031254799

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allfields	10.1007/s13300-018-0554-6 doi (DE-627)SPR031254799 (SPR)s13300-018-0554-6-e DE-627 ger DE-627 rakwb eng 610 VZ Cox, Daniel J. verfasserin (orcid)0000-0002-0910-5306 aut Behavioral Strategies to Lower Postprandial Glucose in Those with Type 2 Diabetes May Also Lower Risk of Coronary Heart Disease 2018 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier © The Author(s) 2018 Introduction Efforts to lower glycosylated hemoglobin (A1c) in patients with type 2 diabetes (T2D) are intended to reduce the risk of diabetic complications, but A1c is not the only factor contributing to this risk. Consequently, we re-analyzed published data from a broad-spectrum lifestyle intervention that lowered A1c to assess its effectiveness in lowering the overall risk of two complications of T2D, namely, coronary heart disease (CHD) and stroke. Methods Data from 37 adults who participated in a randomized clinical trial of a lifestyle intervention intended to reduce postprandial glucose (PPG) were re-analyzed for their pre- and post-treatment risk of CHD and stroke using the T2D-specific UK Prospective Diabetes Study (UKPDS) v2.0 risk algorithm. Results Compared to participants who received routine care, those using the lifestyle intervention had a significantly greater reduction in 10-year risk for CHD, but not for stroke. Conclusion These secondary analyses suggest that broad-spectrum lifestyle interventions that focus on lowering PPG may lower the risk of future CHD, which could guide future research. Trial Registration ClinicalTrials.gov ID: NCT02432391. Behavioral medicine (dpeaa)DE-He213 Coronary disease (dpeaa)DE-He213 Postprandial hyperglycemia (dpeaa)DE-He213 Type 2 diabetes mellitus (dpeaa)DE-He213 Fang, Kun verfasserin aut McCall, Anthony L. verfasserin aut Conaway, Mark R. verfasserin aut Banton, Tom A. verfasserin aut Moncrief, Matthew A. verfasserin aut Diamond, Anne M. verfasserin aut Taylor, Ann G. verfasserin aut Enthalten in Diabetes therapy Springer Healthcare, 2010 10(2018), 1 vom: 18. Dez., Seite 277-281 (DE-627)632439165 (DE-600)2566702-6 1869-6961 nnns volume:10 year:2018 number:1 day:18 month:12 pages:277-281 https://dx.doi.org/10.1007/s13300-018-0554-6 X:SPRINGER Resolving-System kostenfrei Volltext SYSFLAG_0 GBV_SPRINGER SSG-OLC-PHA GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_2005 GBV_ILN_2009 GBV_ILN_2014 GBV_ILN_2055 GBV_ILN_2111 GBV_ILN_2190 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 10 2018 1 18 12 277-281
spelling	10.1007/s13300-018-0554-6 doi (DE-627)SPR031254799 (SPR)s13300-018-0554-6-e DE-627 ger DE-627 rakwb eng 610 VZ Cox, Daniel J. verfasserin (orcid)0000-0002-0910-5306 aut Behavioral Strategies to Lower Postprandial Glucose in Those with Type 2 Diabetes May Also Lower Risk of Coronary Heart Disease 2018 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier © The Author(s) 2018 Introduction Efforts to lower glycosylated hemoglobin (A1c) in patients with type 2 diabetes (T2D) are intended to reduce the risk of diabetic complications, but A1c is not the only factor contributing to this risk. Consequently, we re-analyzed published data from a broad-spectrum lifestyle intervention that lowered A1c to assess its effectiveness in lowering the overall risk of two complications of T2D, namely, coronary heart disease (CHD) and stroke. Methods Data from 37 adults who participated in a randomized clinical trial of a lifestyle intervention intended to reduce postprandial glucose (PPG) were re-analyzed for their pre- and post-treatment risk of CHD and stroke using the T2D-specific UK Prospective Diabetes Study (UKPDS) v2.0 risk algorithm. Results Compared to participants who received routine care, those using the lifestyle intervention had a significantly greater reduction in 10-year risk for CHD, but not for stroke. Conclusion These secondary analyses suggest that broad-spectrum lifestyle interventions that focus on lowering PPG may lower the risk of future CHD, which could guide future research. Trial Registration ClinicalTrials.gov ID: NCT02432391. Behavioral medicine (dpeaa)DE-He213 Coronary disease (dpeaa)DE-He213 Postprandial hyperglycemia (dpeaa)DE-He213 Type 2 diabetes mellitus (dpeaa)DE-He213 Fang, Kun verfasserin aut McCall, Anthony L. verfasserin aut Conaway, Mark R. verfasserin aut Banton, Tom A. verfasserin aut Moncrief, Matthew A. verfasserin aut Diamond, Anne M. verfasserin aut Taylor, Ann G. verfasserin aut Enthalten in Diabetes therapy Springer Healthcare, 2010 10(2018), 1 vom: 18. Dez., Seite 277-281 (DE-627)632439165 (DE-600)2566702-6 1869-6961 nnns volume:10 year:2018 number:1 day:18 month:12 pages:277-281 https://dx.doi.org/10.1007/s13300-018-0554-6 X:SPRINGER Resolving-System kostenfrei Volltext SYSFLAG_0 GBV_SPRINGER SSG-OLC-PHA GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_2005 GBV_ILN_2009 GBV_ILN_2014 GBV_ILN_2055 GBV_ILN_2111 GBV_ILN_2190 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 10 2018 1 18 12 277-281
allfields_unstemmed	10.1007/s13300-018-0554-6 doi (DE-627)SPR031254799 (SPR)s13300-018-0554-6-e DE-627 ger DE-627 rakwb eng 610 VZ Cox, Daniel J. verfasserin (orcid)0000-0002-0910-5306 aut Behavioral Strategies to Lower Postprandial Glucose in Those with Type 2 Diabetes May Also Lower Risk of Coronary Heart Disease 2018 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier © The Author(s) 2018 Introduction Efforts to lower glycosylated hemoglobin (A1c) in patients with type 2 diabetes (T2D) are intended to reduce the risk of diabetic complications, but A1c is not the only factor contributing to this risk. Consequently, we re-analyzed published data from a broad-spectrum lifestyle intervention that lowered A1c to assess its effectiveness in lowering the overall risk of two complications of T2D, namely, coronary heart disease (CHD) and stroke. Methods Data from 37 adults who participated in a randomized clinical trial of a lifestyle intervention intended to reduce postprandial glucose (PPG) were re-analyzed for their pre- and post-treatment risk of CHD and stroke using the T2D-specific UK Prospective Diabetes Study (UKPDS) v2.0 risk algorithm. Results Compared to participants who received routine care, those using the lifestyle intervention had a significantly greater reduction in 10-year risk for CHD, but not for stroke. Conclusion These secondary analyses suggest that broad-spectrum lifestyle interventions that focus on lowering PPG may lower the risk of future CHD, which could guide future research. Trial Registration ClinicalTrials.gov ID: NCT02432391. Behavioral medicine (dpeaa)DE-He213 Coronary disease (dpeaa)DE-He213 Postprandial hyperglycemia (dpeaa)DE-He213 Type 2 diabetes mellitus (dpeaa)DE-He213 Fang, Kun verfasserin aut McCall, Anthony L. verfasserin aut Conaway, Mark R. verfasserin aut Banton, Tom A. verfasserin aut Moncrief, Matthew A. verfasserin aut Diamond, Anne M. verfasserin aut Taylor, Ann G. verfasserin aut Enthalten in Diabetes therapy Springer Healthcare, 2010 10(2018), 1 vom: 18. Dez., Seite 277-281 (DE-627)632439165 (DE-600)2566702-6 1869-6961 nnns volume:10 year:2018 number:1 day:18 month:12 pages:277-281 https://dx.doi.org/10.1007/s13300-018-0554-6 X:SPRINGER Resolving-System kostenfrei Volltext SYSFLAG_0 GBV_SPRINGER SSG-OLC-PHA GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_2005 GBV_ILN_2009 GBV_ILN_2014 GBV_ILN_2055 GBV_ILN_2111 GBV_ILN_2190 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 10 2018 1 18 12 277-281
allfieldsGer	10.1007/s13300-018-0554-6 doi (DE-627)SPR031254799 (SPR)s13300-018-0554-6-e DE-627 ger DE-627 rakwb eng 610 VZ Cox, Daniel J. verfasserin (orcid)0000-0002-0910-5306 aut Behavioral Strategies to Lower Postprandial Glucose in Those with Type 2 Diabetes May Also Lower Risk of Coronary Heart Disease 2018 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier © The Author(s) 2018 Introduction Efforts to lower glycosylated hemoglobin (A1c) in patients with type 2 diabetes (T2D) are intended to reduce the risk of diabetic complications, but A1c is not the only factor contributing to this risk. Consequently, we re-analyzed published data from a broad-spectrum lifestyle intervention that lowered A1c to assess its effectiveness in lowering the overall risk of two complications of T2D, namely, coronary heart disease (CHD) and stroke. Methods Data from 37 adults who participated in a randomized clinical trial of a lifestyle intervention intended to reduce postprandial glucose (PPG) were re-analyzed for their pre- and post-treatment risk of CHD and stroke using the T2D-specific UK Prospective Diabetes Study (UKPDS) v2.0 risk algorithm. Results Compared to participants who received routine care, those using the lifestyle intervention had a significantly greater reduction in 10-year risk for CHD, but not for stroke. Conclusion These secondary analyses suggest that broad-spectrum lifestyle interventions that focus on lowering PPG may lower the risk of future CHD, which could guide future research. Trial Registration ClinicalTrials.gov ID: NCT02432391. Behavioral medicine (dpeaa)DE-He213 Coronary disease (dpeaa)DE-He213 Postprandial hyperglycemia (dpeaa)DE-He213 Type 2 diabetes mellitus (dpeaa)DE-He213 Fang, Kun verfasserin aut McCall, Anthony L. verfasserin aut Conaway, Mark R. verfasserin aut Banton, Tom A. verfasserin aut Moncrief, Matthew A. verfasserin aut Diamond, Anne M. verfasserin aut Taylor, Ann G. verfasserin aut Enthalten in Diabetes therapy Springer Healthcare, 2010 10(2018), 1 vom: 18. Dez., Seite 277-281 (DE-627)632439165 (DE-600)2566702-6 1869-6961 nnns volume:10 year:2018 number:1 day:18 month:12 pages:277-281 https://dx.doi.org/10.1007/s13300-018-0554-6 X:SPRINGER Resolving-System kostenfrei Volltext SYSFLAG_0 GBV_SPRINGER SSG-OLC-PHA GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_2005 GBV_ILN_2009 GBV_ILN_2014 GBV_ILN_2055 GBV_ILN_2111 GBV_ILN_2190 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 10 2018 1 18 12 277-281
allfieldsSound	10.1007/s13300-018-0554-6 doi (DE-627)SPR031254799 (SPR)s13300-018-0554-6-e DE-627 ger DE-627 rakwb eng 610 VZ Cox, Daniel J. verfasserin (orcid)0000-0002-0910-5306 aut Behavioral Strategies to Lower Postprandial Glucose in Those with Type 2 Diabetes May Also Lower Risk of Coronary Heart Disease 2018 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier © The Author(s) 2018 Introduction Efforts to lower glycosylated hemoglobin (A1c) in patients with type 2 diabetes (T2D) are intended to reduce the risk of diabetic complications, but A1c is not the only factor contributing to this risk. Consequently, we re-analyzed published data from a broad-spectrum lifestyle intervention that lowered A1c to assess its effectiveness in lowering the overall risk of two complications of T2D, namely, coronary heart disease (CHD) and stroke. Methods Data from 37 adults who participated in a randomized clinical trial of a lifestyle intervention intended to reduce postprandial glucose (PPG) were re-analyzed for their pre- and post-treatment risk of CHD and stroke using the T2D-specific UK Prospective Diabetes Study (UKPDS) v2.0 risk algorithm. Results Compared to participants who received routine care, those using the lifestyle intervention had a significantly greater reduction in 10-year risk for CHD, but not for stroke. Conclusion These secondary analyses suggest that broad-spectrum lifestyle interventions that focus on lowering PPG may lower the risk of future CHD, which could guide future research. Trial Registration ClinicalTrials.gov ID: NCT02432391. Behavioral medicine (dpeaa)DE-He213 Coronary disease (dpeaa)DE-He213 Postprandial hyperglycemia (dpeaa)DE-He213 Type 2 diabetes mellitus (dpeaa)DE-He213 Fang, Kun verfasserin aut McCall, Anthony L. verfasserin aut Conaway, Mark R. verfasserin aut Banton, Tom A. verfasserin aut Moncrief, Matthew A. verfasserin aut Diamond, Anne M. verfasserin aut Taylor, Ann G. verfasserin aut Enthalten in Diabetes therapy Springer Healthcare, 2010 10(2018), 1 vom: 18. Dez., Seite 277-281 (DE-627)632439165 (DE-600)2566702-6 1869-6961 nnns volume:10 year:2018 number:1 day:18 month:12 pages:277-281 https://dx.doi.org/10.1007/s13300-018-0554-6 X:SPRINGER Resolving-System kostenfrei Volltext SYSFLAG_0 GBV_SPRINGER SSG-OLC-PHA GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_2005 GBV_ILN_2009 GBV_ILN_2014 GBV_ILN_2055 GBV_ILN_2111 GBV_ILN_2190 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 10 2018 1 18 12 277-281
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author	Cox, Daniel J.
spellingShingle	Cox, Daniel J. ddc 610 misc Behavioral medicine misc Coronary disease misc Postprandial hyperglycemia misc Type 2 diabetes mellitus Behavioral Strategies to Lower Postprandial Glucose in Those with Type 2 Diabetes May Also Lower Risk of Coronary Heart Disease
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topic_title	610 VZ Behavioral Strategies to Lower Postprandial Glucose in Those with Type 2 Diabetes May Also Lower Risk of Coronary Heart Disease Behavioral medicine (dpeaa)DE-He213 Coronary disease (dpeaa)DE-He213 Postprandial hyperglycemia (dpeaa)DE-He213 Type 2 diabetes mellitus (dpeaa)DE-He213
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title	Behavioral Strategies to Lower Postprandial Glucose in Those with Type 2 Diabetes May Also Lower Risk of Coronary Heart Disease
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title_full	Behavioral Strategies to Lower Postprandial Glucose in Those with Type 2 Diabetes May Also Lower Risk of Coronary Heart Disease
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title_sort	behavioral strategies to lower postprandial glucose in those with type 2 diabetes may also lower risk of coronary heart disease
title_auth	Behavioral Strategies to Lower Postprandial Glucose in Those with Type 2 Diabetes May Also Lower Risk of Coronary Heart Disease
abstract	Introduction Efforts to lower glycosylated hemoglobin (A1c) in patients with type 2 diabetes (T2D) are intended to reduce the risk of diabetic complications, but A1c is not the only factor contributing to this risk. Consequently, we re-analyzed published data from a broad-spectrum lifestyle intervention that lowered A1c to assess its effectiveness in lowering the overall risk of two complications of T2D, namely, coronary heart disease (CHD) and stroke. Methods Data from 37 adults who participated in a randomized clinical trial of a lifestyle intervention intended to reduce postprandial glucose (PPG) were re-analyzed for their pre- and post-treatment risk of CHD and stroke using the T2D-specific UK Prospective Diabetes Study (UKPDS) v2.0 risk algorithm. Results Compared to participants who received routine care, those using the lifestyle intervention had a significantly greater reduction in 10-year risk for CHD, but not for stroke. Conclusion These secondary analyses suggest that broad-spectrum lifestyle interventions that focus on lowering PPG may lower the risk of future CHD, which could guide future research. Trial Registration ClinicalTrials.gov ID: NCT02432391. © The Author(s) 2018
abstractGer	Introduction Efforts to lower glycosylated hemoglobin (A1c) in patients with type 2 diabetes (T2D) are intended to reduce the risk of diabetic complications, but A1c is not the only factor contributing to this risk. Consequently, we re-analyzed published data from a broad-spectrum lifestyle intervention that lowered A1c to assess its effectiveness in lowering the overall risk of two complications of T2D, namely, coronary heart disease (CHD) and stroke. Methods Data from 37 adults who participated in a randomized clinical trial of a lifestyle intervention intended to reduce postprandial glucose (PPG) were re-analyzed for their pre- and post-treatment risk of CHD and stroke using the T2D-specific UK Prospective Diabetes Study (UKPDS) v2.0 risk algorithm. Results Compared to participants who received routine care, those using the lifestyle intervention had a significantly greater reduction in 10-year risk for CHD, but not for stroke. Conclusion These secondary analyses suggest that broad-spectrum lifestyle interventions that focus on lowering PPG may lower the risk of future CHD, which could guide future research. Trial Registration ClinicalTrials.gov ID: NCT02432391. © The Author(s) 2018
abstract_unstemmed	Introduction Efforts to lower glycosylated hemoglobin (A1c) in patients with type 2 diabetes (T2D) are intended to reduce the risk of diabetic complications, but A1c is not the only factor contributing to this risk. Consequently, we re-analyzed published data from a broad-spectrum lifestyle intervention that lowered A1c to assess its effectiveness in lowering the overall risk of two complications of T2D, namely, coronary heart disease (CHD) and stroke. Methods Data from 37 adults who participated in a randomized clinical trial of a lifestyle intervention intended to reduce postprandial glucose (PPG) were re-analyzed for their pre- and post-treatment risk of CHD and stroke using the T2D-specific UK Prospective Diabetes Study (UKPDS) v2.0 risk algorithm. Results Compared to participants who received routine care, those using the lifestyle intervention had a significantly greater reduction in 10-year risk for CHD, but not for stroke. Conclusion These secondary analyses suggest that broad-spectrum lifestyle interventions that focus on lowering PPG may lower the risk of future CHD, which could guide future research. Trial Registration ClinicalTrials.gov ID: NCT02432391. © The Author(s) 2018
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title_short	Behavioral Strategies to Lower Postprandial Glucose in Those with Type 2 Diabetes May Also Lower Risk of Coronary Heart Disease
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Consequently, we re-analyzed published data from a broad-spectrum lifestyle intervention that lowered A1c to assess its effectiveness in lowering the overall risk of two complications of T2D, namely, coronary heart disease (CHD) and stroke. Methods Data from 37 adults who participated in a randomized clinical trial of a lifestyle intervention intended to reduce postprandial glucose (PPG) were re-analyzed for their pre- and post-treatment risk of CHD and stroke using the T2D-specific UK Prospective Diabetes Study (UKPDS) v2.0 risk algorithm. Results Compared to participants who received routine care, those using the lifestyle intervention had a significantly greater reduction in 10-year risk for CHD, but not for stroke. Conclusion These secondary analyses suggest that broad-spectrum lifestyle interventions that focus on lowering PPG may lower the risk of future CHD, which could guide future research. 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Behavioral Strategies to Lower Postprandial Glucose in Those with Type 2 Diabetes May Also Lower Risk of Coronary Heart Disease

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