Intracranial hemorrhage following intrathecal methotrexate therapy for acute lymphoblastic leukaemia
Background Acute toxic leukoencephalopathy following intrathecal methotrexate administration is well documented but intracranial haemorrhage is extremely rare. Case Characteristics A 2½-year-old girl with acute lymphoblastic leukemia developed sudden onset neurological deterioration following intrat...
Ausführliche Beschreibung
Gespeichert in:
| Autor*in: |
Purkait, Radheshyam [verfasserIn] |
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| Format: |
E-Artikel |
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| Sprache: |
Englisch |
| Erschienen: |
2016 |
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| Schlagwörter: |
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| Anmerkung: |
© Indian Academy of Pediatrics 2016 |
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| Übergeordnetes Werk: |
Enthalten in: Indian Pediatrics - Springer-Verlag, 2010, 53(2016), 5 vom: Mai, Seite 423-424 |
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| Übergeordnetes Werk: |
volume:53 ; year:2016 ; number:5 ; month:05 ; pages:423-424 |
| Links: |
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| DOI / URN: |
10.1007/s13312-016-0866-4 |
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SPR031291058 |
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| 520 | |a Background Acute toxic leukoencephalopathy following intrathecal methotrexate administration is well documented but intracranial haemorrhage is extremely rare. Case Characteristics A 2½-year-old girl with acute lymphoblastic leukemia developed sudden onset neurological deterioration following intrathecal methotrexate. Observations Computed tomography scan of brain demonstrated intraventricular and subarachnoid hemorrhage. Outcome Child improved gradually on conservative management. Follow-up neuroimaging showed resolution of hemorrhage. Message Intracranial haemorrhage is a rare but serious complication of intrathecal methotrexate. | ||
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10.1007/s13312-016-0866-4 doi (DE-627)SPR031291058 (SPR)s13312-016-0866-4-e DE-627 ger DE-627 rakwb eng Purkait, Radheshyam verfasserin aut Intracranial hemorrhage following intrathecal methotrexate therapy for acute lymphoblastic leukaemia 2016 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier © Indian Academy of Pediatrics 2016 Background Acute toxic leukoencephalopathy following intrathecal methotrexate administration is well documented but intracranial haemorrhage is extremely rare. Case Characteristics A 2½-year-old girl with acute lymphoblastic leukemia developed sudden onset neurological deterioration following intrathecal methotrexate. Observations Computed tomography scan of brain demonstrated intraventricular and subarachnoid hemorrhage. Outcome Child improved gradually on conservative management. Follow-up neuroimaging showed resolution of hemorrhage. Message Intracranial haemorrhage is a rare but serious complication of intrathecal methotrexate. Chemotherapy (dpeaa)DE-He213 Complications (dpeaa)DE-He213 Malignancy (dpeaa)DE-He213 Neurological events (dpeaa)DE-He213 Dolai, Tuphan Kanti aut Lath, Chinmoy aut Das, Biswajit aut Enthalten in Indian Pediatrics Springer-Verlag, 2010 53(2016), 5 vom: Mai, Seite 423-424 (DE-627)SPR031274943 nnns volume:53 year:2016 number:5 month:05 pages:423-424 https://dx.doi.org/10.1007/s13312-016-0866-4 lizenzpflichtig Volltext GBV_USEFLAG_A SYSFLAG_A GBV_SPRINGER GBV_ILN_11 GBV_ILN_20 GBV_ILN_22 GBV_ILN_70 GBV_ILN_72 GBV_ILN_110 GBV_ILN_131 GBV_ILN_160 GBV_ILN_376 GBV_ILN_607 AR 53 2016 5 05 423-424 |
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10.1007/s13312-016-0866-4 doi (DE-627)SPR031291058 (SPR)s13312-016-0866-4-e DE-627 ger DE-627 rakwb eng Purkait, Radheshyam verfasserin aut Intracranial hemorrhage following intrathecal methotrexate therapy for acute lymphoblastic leukaemia 2016 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier © Indian Academy of Pediatrics 2016 Background Acute toxic leukoencephalopathy following intrathecal methotrexate administration is well documented but intracranial haemorrhage is extremely rare. Case Characteristics A 2½-year-old girl with acute lymphoblastic leukemia developed sudden onset neurological deterioration following intrathecal methotrexate. Observations Computed tomography scan of brain demonstrated intraventricular and subarachnoid hemorrhage. Outcome Child improved gradually on conservative management. Follow-up neuroimaging showed resolution of hemorrhage. Message Intracranial haemorrhage is a rare but serious complication of intrathecal methotrexate. Chemotherapy (dpeaa)DE-He213 Complications (dpeaa)DE-He213 Malignancy (dpeaa)DE-He213 Neurological events (dpeaa)DE-He213 Dolai, Tuphan Kanti aut Lath, Chinmoy aut Das, Biswajit aut Enthalten in Indian Pediatrics Springer-Verlag, 2010 53(2016), 5 vom: Mai, Seite 423-424 (DE-627)SPR031274943 nnns volume:53 year:2016 number:5 month:05 pages:423-424 https://dx.doi.org/10.1007/s13312-016-0866-4 lizenzpflichtig Volltext GBV_USEFLAG_A SYSFLAG_A GBV_SPRINGER GBV_ILN_11 GBV_ILN_20 GBV_ILN_22 GBV_ILN_70 GBV_ILN_72 GBV_ILN_110 GBV_ILN_131 GBV_ILN_160 GBV_ILN_376 GBV_ILN_607 AR 53 2016 5 05 423-424 |
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10.1007/s13312-016-0866-4 doi (DE-627)SPR031291058 (SPR)s13312-016-0866-4-e DE-627 ger DE-627 rakwb eng Purkait, Radheshyam verfasserin aut Intracranial hemorrhage following intrathecal methotrexate therapy for acute lymphoblastic leukaemia 2016 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier © Indian Academy of Pediatrics 2016 Background Acute toxic leukoencephalopathy following intrathecal methotrexate administration is well documented but intracranial haemorrhage is extremely rare. Case Characteristics A 2½-year-old girl with acute lymphoblastic leukemia developed sudden onset neurological deterioration following intrathecal methotrexate. Observations Computed tomography scan of brain demonstrated intraventricular and subarachnoid hemorrhage. Outcome Child improved gradually on conservative management. Follow-up neuroimaging showed resolution of hemorrhage. Message Intracranial haemorrhage is a rare but serious complication of intrathecal methotrexate. Chemotherapy (dpeaa)DE-He213 Complications (dpeaa)DE-He213 Malignancy (dpeaa)DE-He213 Neurological events (dpeaa)DE-He213 Dolai, Tuphan Kanti aut Lath, Chinmoy aut Das, Biswajit aut Enthalten in Indian Pediatrics Springer-Verlag, 2010 53(2016), 5 vom: Mai, Seite 423-424 (DE-627)SPR031274943 nnns volume:53 year:2016 number:5 month:05 pages:423-424 https://dx.doi.org/10.1007/s13312-016-0866-4 lizenzpflichtig Volltext GBV_USEFLAG_A SYSFLAG_A GBV_SPRINGER GBV_ILN_11 GBV_ILN_20 GBV_ILN_22 GBV_ILN_70 GBV_ILN_72 GBV_ILN_110 GBV_ILN_131 GBV_ILN_160 GBV_ILN_376 GBV_ILN_607 AR 53 2016 5 05 423-424 |
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Background Acute toxic leukoencephalopathy following intrathecal methotrexate administration is well documented but intracranial haemorrhage is extremely rare. Case Characteristics A 2½-year-old girl with acute lymphoblastic leukemia developed sudden onset neurological deterioration following intrathecal methotrexate. Observations Computed tomography scan of brain demonstrated intraventricular and subarachnoid hemorrhage. Outcome Child improved gradually on conservative management. Follow-up neuroimaging showed resolution of hemorrhage. Message Intracranial haemorrhage is a rare but serious complication of intrathecal methotrexate. © Indian Academy of Pediatrics 2016 |
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Background Acute toxic leukoencephalopathy following intrathecal methotrexate administration is well documented but intracranial haemorrhage is extremely rare. Case Characteristics A 2½-year-old girl with acute lymphoblastic leukemia developed sudden onset neurological deterioration following intrathecal methotrexate. Observations Computed tomography scan of brain demonstrated intraventricular and subarachnoid hemorrhage. Outcome Child improved gradually on conservative management. Follow-up neuroimaging showed resolution of hemorrhage. Message Intracranial haemorrhage is a rare but serious complication of intrathecal methotrexate. © Indian Academy of Pediatrics 2016 |
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Background Acute toxic leukoencephalopathy following intrathecal methotrexate administration is well documented but intracranial haemorrhage is extremely rare. Case Characteristics A 2½-year-old girl with acute lymphoblastic leukemia developed sudden onset neurological deterioration following intrathecal methotrexate. Observations Computed tomography scan of brain demonstrated intraventricular and subarachnoid hemorrhage. Outcome Child improved gradually on conservative management. Follow-up neuroimaging showed resolution of hemorrhage. Message Intracranial haemorrhage is a rare but serious complication of intrathecal methotrexate. © Indian Academy of Pediatrics 2016 |
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<?xml version="1.0" encoding="UTF-8"?><collection xmlns="http://www.loc.gov/MARC21/slim"><record><leader>01000caa a22002652 4500</leader><controlfield tag="001">SPR031291058</controlfield><controlfield tag="003">DE-627</controlfield><controlfield tag="005">20230331071334.0</controlfield><controlfield tag="007">cr uuu---uuuuu</controlfield><controlfield tag="008">201007s2016 xx |||||o 00| ||eng c</controlfield><datafield tag="024" ind1="7" ind2=" "><subfield code="a">10.1007/s13312-016-0866-4</subfield><subfield code="2">doi</subfield></datafield><datafield tag="035" ind1=" " ind2=" "><subfield code="a">(DE-627)SPR031291058</subfield></datafield><datafield tag="035" ind1=" " ind2=" "><subfield code="a">(SPR)s13312-016-0866-4-e</subfield></datafield><datafield tag="040" ind1=" " ind2=" "><subfield code="a">DE-627</subfield><subfield code="b">ger</subfield><subfield code="c">DE-627</subfield><subfield code="e">rakwb</subfield></datafield><datafield tag="041" ind1=" " ind2=" "><subfield code="a">eng</subfield></datafield><datafield tag="100" ind1="1" ind2=" "><subfield code="a">Purkait, Radheshyam</subfield><subfield code="e">verfasserin</subfield><subfield code="4">aut</subfield></datafield><datafield tag="245" ind1="1" ind2="0"><subfield code="a">Intracranial hemorrhage following intrathecal methotrexate therapy for acute lymphoblastic leukaemia</subfield></datafield><datafield tag="264" ind1=" " ind2="1"><subfield code="c">2016</subfield></datafield><datafield tag="336" ind1=" " ind2=" "><subfield code="a">Text</subfield><subfield code="b">txt</subfield><subfield code="2">rdacontent</subfield></datafield><datafield tag="337" ind1=" " ind2=" "><subfield code="a">Computermedien</subfield><subfield code="b">c</subfield><subfield code="2">rdamedia</subfield></datafield><datafield tag="338" ind1=" " ind2=" "><subfield code="a">Online-Ressource</subfield><subfield code="b">cr</subfield><subfield code="2">rdacarrier</subfield></datafield><datafield tag="500" ind1=" " ind2=" "><subfield code="a">© Indian Academy of Pediatrics 2016</subfield></datafield><datafield tag="520" ind1=" " ind2=" "><subfield code="a">Background Acute toxic leukoencephalopathy following intrathecal methotrexate administration is well documented but intracranial haemorrhage is extremely rare. Case Characteristics A 2½-year-old girl with acute lymphoblastic leukemia developed sudden onset neurological deterioration following intrathecal methotrexate. Observations Computed tomography scan of brain demonstrated intraventricular and subarachnoid hemorrhage. Outcome Child improved gradually on conservative management. Follow-up neuroimaging showed resolution of hemorrhage. 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