Diagnostic Yield of Xpert MTB/RIF in Bronchoalveolar Lavage in Children with Probable Pulmonary Tuberculosis
Objective To evaluate utility of Xpert MTB/RIF in bronchoalveolar lavage fluid in children with probable pulmonary tuberculosis. Methods Children with probable pulmonary tuberculosis with negative smear and Xpert on induced sputum/gastric aspirate were subjected to bronchoalveolar lavage (BAL) for X...
Ausführliche Beschreibung
Gespeichert in:
| Autor*in: |
Saini, Isha [verfasserIn] |
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| Format: |
E-Artikel |
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| Sprache: |
Englisch |
| Erschienen: |
2018 |
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| Schlagwörter: |
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| Anmerkung: |
© Indian Academy of Pediatrics 2018 |
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| Übergeordnetes Werk: |
Enthalten in: Indian Pediatrics - Springer-Verlag, 2010, 55(2018), 12 vom: Dez., Seite 1062-1065 |
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| Übergeordnetes Werk: |
volume:55 ; year:2018 ; number:12 ; month:12 ; pages:1062-1065 |
| Links: |
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| DOI / URN: |
10.1007/s13312-018-1443-9 |
|---|
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SPR031295355 |
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| 520 | |a Objective To evaluate utility of Xpert MTB/RIF in bronchoalveolar lavage fluid in children with probable pulmonary tuberculosis. Methods Children with probable pulmonary tuberculosis with negative smear and Xpert on induced sputum/gastric aspirate were subjected to bronchoalveolar lavage (BAL) for Xpert assay and mycobacterial liquid culture. Data of children <14 y undergoing bronchoscopy for suspected MDR-TB (n=12) were also analyzed. The sensitivity of Xpert in BAL fluid for diagnosis of probable and confirmed pulmonary tuberculosis was calculated with clinico-radiological diagnosis and culture as gold standards, respectively. Results Of 41 enrolled children, 24 (58.5%) had Xpert positive in BAL fluid and 11 (26.8%) had culture confirmed tuberculosis (BAL fluid;10; sputum,1). The sensitivity of Xpert in BAL fluid among probable and culture confirmed tuberculosis cases was 58.5% (24/41) and 81.8% (9/11), respectively. Conclusion Xpert in bronchoalveolar lavage fluid has good sensitivity in both probable and confirmed pulmonary tuberculosis in children. | ||
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| 700 | 1 | |a Mukherjee, Aparna |4 aut | |
| 700 | 1 | |a Gautam, Hitender |4 aut | |
| 700 | 1 | |a Singla, Mohit |4 aut | |
| 700 | 1 | |a Jat, Kr |4 aut | |
| 700 | 1 | |a Lodha, Rakesh |4 aut | |
| 700 | 1 | |a Singh, Urvashi B |4 aut | |
| 700 | 1 | |a Kabra, Sk |4 aut | |
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10.1007/s13312-018-1443-9 doi (DE-627)SPR031295355 (SPR)s13312-018-1443-9-e DE-627 ger DE-627 rakwb eng Saini, Isha verfasserin aut Diagnostic Yield of Xpert MTB/RIF in Bronchoalveolar Lavage in Children with Probable Pulmonary Tuberculosis 2018 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier © Indian Academy of Pediatrics 2018 Objective To evaluate utility of Xpert MTB/RIF in bronchoalveolar lavage fluid in children with probable pulmonary tuberculosis. Methods Children with probable pulmonary tuberculosis with negative smear and Xpert on induced sputum/gastric aspirate were subjected to bronchoalveolar lavage (BAL) for Xpert assay and mycobacterial liquid culture. Data of children <14 y undergoing bronchoscopy for suspected MDR-TB (n=12) were also analyzed. The sensitivity of Xpert in BAL fluid for diagnosis of probable and confirmed pulmonary tuberculosis was calculated with clinico-radiological diagnosis and culture as gold standards, respectively. Results Of 41 enrolled children, 24 (58.5%) had Xpert positive in BAL fluid and 11 (26.8%) had culture confirmed tuberculosis (BAL fluid;10; sputum,1). The sensitivity of Xpert in BAL fluid among probable and culture confirmed tuberculosis cases was 58.5% (24/41) and 81.8% (9/11), respectively. Conclusion Xpert in bronchoalveolar lavage fluid has good sensitivity in both probable and confirmed pulmonary tuberculosis in children. Bronchoscopy (dpeaa)DE-He213 CBNAAT (dpeaa)DE-He213 Pediatric TB (dpeaa)DE-He213 Mukherjee, Aparna aut Gautam, Hitender aut Singla, Mohit aut Jat, Kr aut Lodha, Rakesh aut Singh, Urvashi B aut Kabra, Sk aut Enthalten in Indian Pediatrics Springer-Verlag, 2010 55(2018), 12 vom: Dez., Seite 1062-1065 (DE-627)SPR031274943 nnns volume:55 year:2018 number:12 month:12 pages:1062-1065 https://dx.doi.org/10.1007/s13312-018-1443-9 lizenzpflichtig Volltext GBV_USEFLAG_A SYSFLAG_A GBV_SPRINGER GBV_ILN_11 GBV_ILN_20 GBV_ILN_22 GBV_ILN_70 GBV_ILN_72 GBV_ILN_110 GBV_ILN_131 GBV_ILN_160 GBV_ILN_376 GBV_ILN_607 AR 55 2018 12 12 1062-1065 |
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10.1007/s13312-018-1443-9 doi (DE-627)SPR031295355 (SPR)s13312-018-1443-9-e DE-627 ger DE-627 rakwb eng Saini, Isha verfasserin aut Diagnostic Yield of Xpert MTB/RIF in Bronchoalveolar Lavage in Children with Probable Pulmonary Tuberculosis 2018 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier © Indian Academy of Pediatrics 2018 Objective To evaluate utility of Xpert MTB/RIF in bronchoalveolar lavage fluid in children with probable pulmonary tuberculosis. Methods Children with probable pulmonary tuberculosis with negative smear and Xpert on induced sputum/gastric aspirate were subjected to bronchoalveolar lavage (BAL) for Xpert assay and mycobacterial liquid culture. Data of children <14 y undergoing bronchoscopy for suspected MDR-TB (n=12) were also analyzed. The sensitivity of Xpert in BAL fluid for diagnosis of probable and confirmed pulmonary tuberculosis was calculated with clinico-radiological diagnosis and culture as gold standards, respectively. Results Of 41 enrolled children, 24 (58.5%) had Xpert positive in BAL fluid and 11 (26.8%) had culture confirmed tuberculosis (BAL fluid;10; sputum,1). The sensitivity of Xpert in BAL fluid among probable and culture confirmed tuberculosis cases was 58.5% (24/41) and 81.8% (9/11), respectively. Conclusion Xpert in bronchoalveolar lavage fluid has good sensitivity in both probable and confirmed pulmonary tuberculosis in children. Bronchoscopy (dpeaa)DE-He213 CBNAAT (dpeaa)DE-He213 Pediatric TB (dpeaa)DE-He213 Mukherjee, Aparna aut Gautam, Hitender aut Singla, Mohit aut Jat, Kr aut Lodha, Rakesh aut Singh, Urvashi B aut Kabra, Sk aut Enthalten in Indian Pediatrics Springer-Verlag, 2010 55(2018), 12 vom: Dez., Seite 1062-1065 (DE-627)SPR031274943 nnns volume:55 year:2018 number:12 month:12 pages:1062-1065 https://dx.doi.org/10.1007/s13312-018-1443-9 lizenzpflichtig Volltext GBV_USEFLAG_A SYSFLAG_A GBV_SPRINGER GBV_ILN_11 GBV_ILN_20 GBV_ILN_22 GBV_ILN_70 GBV_ILN_72 GBV_ILN_110 GBV_ILN_131 GBV_ILN_160 GBV_ILN_376 GBV_ILN_607 AR 55 2018 12 12 1062-1065 |
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10.1007/s13312-018-1443-9 doi (DE-627)SPR031295355 (SPR)s13312-018-1443-9-e DE-627 ger DE-627 rakwb eng Saini, Isha verfasserin aut Diagnostic Yield of Xpert MTB/RIF in Bronchoalveolar Lavage in Children with Probable Pulmonary Tuberculosis 2018 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier © Indian Academy of Pediatrics 2018 Objective To evaluate utility of Xpert MTB/RIF in bronchoalveolar lavage fluid in children with probable pulmonary tuberculosis. Methods Children with probable pulmonary tuberculosis with negative smear and Xpert on induced sputum/gastric aspirate were subjected to bronchoalveolar lavage (BAL) for Xpert assay and mycobacterial liquid culture. Data of children <14 y undergoing bronchoscopy for suspected MDR-TB (n=12) were also analyzed. The sensitivity of Xpert in BAL fluid for diagnosis of probable and confirmed pulmonary tuberculosis was calculated with clinico-radiological diagnosis and culture as gold standards, respectively. Results Of 41 enrolled children, 24 (58.5%) had Xpert positive in BAL fluid and 11 (26.8%) had culture confirmed tuberculosis (BAL fluid;10; sputum,1). The sensitivity of Xpert in BAL fluid among probable and culture confirmed tuberculosis cases was 58.5% (24/41) and 81.8% (9/11), respectively. Conclusion Xpert in bronchoalveolar lavage fluid has good sensitivity in both probable and confirmed pulmonary tuberculosis in children. Bronchoscopy (dpeaa)DE-He213 CBNAAT (dpeaa)DE-He213 Pediatric TB (dpeaa)DE-He213 Mukherjee, Aparna aut Gautam, Hitender aut Singla, Mohit aut Jat, Kr aut Lodha, Rakesh aut Singh, Urvashi B aut Kabra, Sk aut Enthalten in Indian Pediatrics Springer-Verlag, 2010 55(2018), 12 vom: Dez., Seite 1062-1065 (DE-627)SPR031274943 nnns volume:55 year:2018 number:12 month:12 pages:1062-1065 https://dx.doi.org/10.1007/s13312-018-1443-9 lizenzpflichtig Volltext GBV_USEFLAG_A SYSFLAG_A GBV_SPRINGER GBV_ILN_11 GBV_ILN_20 GBV_ILN_22 GBV_ILN_70 GBV_ILN_72 GBV_ILN_110 GBV_ILN_131 GBV_ILN_160 GBV_ILN_376 GBV_ILN_607 AR 55 2018 12 12 1062-1065 |
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10.1007/s13312-018-1443-9 doi (DE-627)SPR031295355 (SPR)s13312-018-1443-9-e DE-627 ger DE-627 rakwb eng Saini, Isha verfasserin aut Diagnostic Yield of Xpert MTB/RIF in Bronchoalveolar Lavage in Children with Probable Pulmonary Tuberculosis 2018 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier © Indian Academy of Pediatrics 2018 Objective To evaluate utility of Xpert MTB/RIF in bronchoalveolar lavage fluid in children with probable pulmonary tuberculosis. Methods Children with probable pulmonary tuberculosis with negative smear and Xpert on induced sputum/gastric aspirate were subjected to bronchoalveolar lavage (BAL) for Xpert assay and mycobacterial liquid culture. Data of children <14 y undergoing bronchoscopy for suspected MDR-TB (n=12) were also analyzed. The sensitivity of Xpert in BAL fluid for diagnosis of probable and confirmed pulmonary tuberculosis was calculated with clinico-radiological diagnosis and culture as gold standards, respectively. Results Of 41 enrolled children, 24 (58.5%) had Xpert positive in BAL fluid and 11 (26.8%) had culture confirmed tuberculosis (BAL fluid;10; sputum,1). The sensitivity of Xpert in BAL fluid among probable and culture confirmed tuberculosis cases was 58.5% (24/41) and 81.8% (9/11), respectively. Conclusion Xpert in bronchoalveolar lavage fluid has good sensitivity in both probable and confirmed pulmonary tuberculosis in children. Bronchoscopy (dpeaa)DE-He213 CBNAAT (dpeaa)DE-He213 Pediatric TB (dpeaa)DE-He213 Mukherjee, Aparna aut Gautam, Hitender aut Singla, Mohit aut Jat, Kr aut Lodha, Rakesh aut Singh, Urvashi B aut Kabra, Sk aut Enthalten in Indian Pediatrics Springer-Verlag, 2010 55(2018), 12 vom: Dez., Seite 1062-1065 (DE-627)SPR031274943 nnns volume:55 year:2018 number:12 month:12 pages:1062-1065 https://dx.doi.org/10.1007/s13312-018-1443-9 lizenzpflichtig Volltext GBV_USEFLAG_A SYSFLAG_A GBV_SPRINGER GBV_ILN_11 GBV_ILN_20 GBV_ILN_22 GBV_ILN_70 GBV_ILN_72 GBV_ILN_110 GBV_ILN_131 GBV_ILN_160 GBV_ILN_376 GBV_ILN_607 AR 55 2018 12 12 1062-1065 |
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10.1007/s13312-018-1443-9 doi (DE-627)SPR031295355 (SPR)s13312-018-1443-9-e DE-627 ger DE-627 rakwb eng Saini, Isha verfasserin aut Diagnostic Yield of Xpert MTB/RIF in Bronchoalveolar Lavage in Children with Probable Pulmonary Tuberculosis 2018 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier © Indian Academy of Pediatrics 2018 Objective To evaluate utility of Xpert MTB/RIF in bronchoalveolar lavage fluid in children with probable pulmonary tuberculosis. Methods Children with probable pulmonary tuberculosis with negative smear and Xpert on induced sputum/gastric aspirate were subjected to bronchoalveolar lavage (BAL) for Xpert assay and mycobacterial liquid culture. Data of children <14 y undergoing bronchoscopy for suspected MDR-TB (n=12) were also analyzed. The sensitivity of Xpert in BAL fluid for diagnosis of probable and confirmed pulmonary tuberculosis was calculated with clinico-radiological diagnosis and culture as gold standards, respectively. Results Of 41 enrolled children, 24 (58.5%) had Xpert positive in BAL fluid and 11 (26.8%) had culture confirmed tuberculosis (BAL fluid;10; sputum,1). The sensitivity of Xpert in BAL fluid among probable and culture confirmed tuberculosis cases was 58.5% (24/41) and 81.8% (9/11), respectively. Conclusion Xpert in bronchoalveolar lavage fluid has good sensitivity in both probable and confirmed pulmonary tuberculosis in children. Bronchoscopy (dpeaa)DE-He213 CBNAAT (dpeaa)DE-He213 Pediatric TB (dpeaa)DE-He213 Mukherjee, Aparna aut Gautam, Hitender aut Singla, Mohit aut Jat, Kr aut Lodha, Rakesh aut Singh, Urvashi B aut Kabra, Sk aut Enthalten in Indian Pediatrics Springer-Verlag, 2010 55(2018), 12 vom: Dez., Seite 1062-1065 (DE-627)SPR031274943 nnns volume:55 year:2018 number:12 month:12 pages:1062-1065 https://dx.doi.org/10.1007/s13312-018-1443-9 lizenzpflichtig Volltext GBV_USEFLAG_A SYSFLAG_A GBV_SPRINGER GBV_ILN_11 GBV_ILN_20 GBV_ILN_22 GBV_ILN_70 GBV_ILN_72 GBV_ILN_110 GBV_ILN_131 GBV_ILN_160 GBV_ILN_376 GBV_ILN_607 AR 55 2018 12 12 1062-1065 |
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Saini, Isha Mukherjee, Aparna Gautam, Hitender Singla, Mohit Jat, Kr Lodha, Rakesh Singh, Urvashi B Kabra, Sk |
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Saini, Isha |
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10.1007/s13312-018-1443-9 |
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diagnostic yield of xpert mtb/rif in bronchoalveolar lavage in children with probable pulmonary tuberculosis |
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Diagnostic Yield of Xpert MTB/RIF in Bronchoalveolar Lavage in Children with Probable Pulmonary Tuberculosis |
| abstract |
Objective To evaluate utility of Xpert MTB/RIF in bronchoalveolar lavage fluid in children with probable pulmonary tuberculosis. Methods Children with probable pulmonary tuberculosis with negative smear and Xpert on induced sputum/gastric aspirate were subjected to bronchoalveolar lavage (BAL) for Xpert assay and mycobacterial liquid culture. Data of children <14 y undergoing bronchoscopy for suspected MDR-TB (n=12) were also analyzed. The sensitivity of Xpert in BAL fluid for diagnosis of probable and confirmed pulmonary tuberculosis was calculated with clinico-radiological diagnosis and culture as gold standards, respectively. Results Of 41 enrolled children, 24 (58.5%) had Xpert positive in BAL fluid and 11 (26.8%) had culture confirmed tuberculosis (BAL fluid;10; sputum,1). The sensitivity of Xpert in BAL fluid among probable and culture confirmed tuberculosis cases was 58.5% (24/41) and 81.8% (9/11), respectively. Conclusion Xpert in bronchoalveolar lavage fluid has good sensitivity in both probable and confirmed pulmonary tuberculosis in children. © Indian Academy of Pediatrics 2018 |
| abstractGer |
Objective To evaluate utility of Xpert MTB/RIF in bronchoalveolar lavage fluid in children with probable pulmonary tuberculosis. Methods Children with probable pulmonary tuberculosis with negative smear and Xpert on induced sputum/gastric aspirate were subjected to bronchoalveolar lavage (BAL) for Xpert assay and mycobacterial liquid culture. Data of children <14 y undergoing bronchoscopy for suspected MDR-TB (n=12) were also analyzed. The sensitivity of Xpert in BAL fluid for diagnosis of probable and confirmed pulmonary tuberculosis was calculated with clinico-radiological diagnosis and culture as gold standards, respectively. Results Of 41 enrolled children, 24 (58.5%) had Xpert positive in BAL fluid and 11 (26.8%) had culture confirmed tuberculosis (BAL fluid;10; sputum,1). The sensitivity of Xpert in BAL fluid among probable and culture confirmed tuberculosis cases was 58.5% (24/41) and 81.8% (9/11), respectively. Conclusion Xpert in bronchoalveolar lavage fluid has good sensitivity in both probable and confirmed pulmonary tuberculosis in children. © Indian Academy of Pediatrics 2018 |
| abstract_unstemmed |
Objective To evaluate utility of Xpert MTB/RIF in bronchoalveolar lavage fluid in children with probable pulmonary tuberculosis. Methods Children with probable pulmonary tuberculosis with negative smear and Xpert on induced sputum/gastric aspirate were subjected to bronchoalveolar lavage (BAL) for Xpert assay and mycobacterial liquid culture. Data of children <14 y undergoing bronchoscopy for suspected MDR-TB (n=12) were also analyzed. The sensitivity of Xpert in BAL fluid for diagnosis of probable and confirmed pulmonary tuberculosis was calculated with clinico-radiological diagnosis and culture as gold standards, respectively. Results Of 41 enrolled children, 24 (58.5%) had Xpert positive in BAL fluid and 11 (26.8%) had culture confirmed tuberculosis (BAL fluid;10; sputum,1). The sensitivity of Xpert in BAL fluid among probable and culture confirmed tuberculosis cases was 58.5% (24/41) and 81.8% (9/11), respectively. Conclusion Xpert in bronchoalveolar lavage fluid has good sensitivity in both probable and confirmed pulmonary tuberculosis in children. © Indian Academy of Pediatrics 2018 |
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| title_short |
Diagnostic Yield of Xpert MTB/RIF in Bronchoalveolar Lavage in Children with Probable Pulmonary Tuberculosis |
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