Alteration of red blood cell aggregation during blood storage
Abstract Even though the trade-off between the benefits and risks of blood transfusion has been discussed for the last several decades, it requires further understanding of the rheological changes in stored blood that include the alteration of red blood cell (RBC) aggregation. The RBC aggregation of...
Ausführliche Beschreibung
Autor*in: |
Lim, Hyun-Jung [verfasserIn] Nam, Jeong-Hun [verfasserIn] Lee, Byoung-Kwon [verfasserIn] Suh, Jang-Soo [verfasserIn] Shin, Sehyun [verfasserIn] |
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Sprache: |
Englisch |
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2011 |
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Enthalten in: Korea-Australia Rheology Journal - Korean Society of Rheology, Australian Society of Rheology, 2011, 23(2011), 2 vom: Juni, Seite 67-70 |
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Übergeordnetes Werk: |
volume:23 ; year:2011 ; number:2 ; month:06 ; pages:67-70 |
Links: |
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DOI / URN: |
10.1007/s13367-011-0009-3 |
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SPR031694160 |
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520 | |a Abstract Even though the trade-off between the benefits and risks of blood transfusion has been discussed for the last several decades, it requires further understanding of the rheological changes in stored blood that include the alteration of red blood cell (RBC) aggregation. The RBC aggregation of stored blood in its autologous plasma was monitored through the storage period (35 days). The critical shear stress, as a measure of RBC aggregation, was determined by using a microfluidic aggregometer. Blood was processed into a blood bag containing the anticoagulant CPDA1 and stored at 4°C. It was subjected to assays after zero, seven, 14, and 35 days. The critical shear stress for stored blood did not change up to 14 days of storage but exhibited a significant decrease after 35 days of storage. These results were identical to those of the conventional aggregation index (AI). Also, in the alteration of RBC aggregation for blood storage, the effect of the plasma factor was slightly stronger than that of the cellular factor. Through the present study, the critical shear stress as a new measure of RBC aggregation may help to monitor and control the quality of blood storage. | ||
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10.1007/s13367-011-0009-3 doi (DE-627)SPR031694160 (SPR)s13367-011-0009-3-e DE-627 ger DE-627 rakwb eng Lim, Hyun-Jung verfasserin aut Alteration of red blood cell aggregation during blood storage 2011 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Abstract Even though the trade-off between the benefits and risks of blood transfusion has been discussed for the last several decades, it requires further understanding of the rheological changes in stored blood that include the alteration of red blood cell (RBC) aggregation. The RBC aggregation of stored blood in its autologous plasma was monitored through the storage period (35 days). The critical shear stress, as a measure of RBC aggregation, was determined by using a microfluidic aggregometer. Blood was processed into a blood bag containing the anticoagulant CPDA1 and stored at 4°C. It was subjected to assays after zero, seven, 14, and 35 days. The critical shear stress for stored blood did not change up to 14 days of storage but exhibited a significant decrease after 35 days of storage. These results were identical to those of the conventional aggregation index (AI). Also, in the alteration of RBC aggregation for blood storage, the effect of the plasma factor was slightly stronger than that of the cellular factor. Through the present study, the critical shear stress as a new measure of RBC aggregation may help to monitor and control the quality of blood storage. RBC (dpeaa)DE-He213 aggregation (dpeaa)DE-He213 blood (dpeaa)DE-He213 storage (dpeaa)DE-He213 critical shear stress (dpeaa)DE-He213 Nam, Jeong-Hun verfasserin aut Lee, Byoung-Kwon verfasserin aut Suh, Jang-Soo verfasserin aut Shin, Sehyun verfasserin aut Enthalten in Korea-Australia Rheology Journal Korean Society of Rheology, Australian Society of Rheology, 2011 23(2011), 2 vom: Juni, Seite 67-70 (DE-627)SPR031694004 nnns volume:23 year:2011 number:2 month:06 pages:67-70 https://dx.doi.org/10.1007/s13367-011-0009-3 lizenzpflichtig Volltext GBV_USEFLAG_A SYSFLAG_A GBV_SPRINGER GBV_ILN_20 GBV_ILN_21 GBV_ILN_70 AR 23 2011 2 06 67-70 |
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10.1007/s13367-011-0009-3 doi (DE-627)SPR031694160 (SPR)s13367-011-0009-3-e DE-627 ger DE-627 rakwb eng Lim, Hyun-Jung verfasserin aut Alteration of red blood cell aggregation during blood storage 2011 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Abstract Even though the trade-off between the benefits and risks of blood transfusion has been discussed for the last several decades, it requires further understanding of the rheological changes in stored blood that include the alteration of red blood cell (RBC) aggregation. The RBC aggregation of stored blood in its autologous plasma was monitored through the storage period (35 days). The critical shear stress, as a measure of RBC aggregation, was determined by using a microfluidic aggregometer. Blood was processed into a blood bag containing the anticoagulant CPDA1 and stored at 4°C. It was subjected to assays after zero, seven, 14, and 35 days. The critical shear stress for stored blood did not change up to 14 days of storage but exhibited a significant decrease after 35 days of storage. These results were identical to those of the conventional aggregation index (AI). Also, in the alteration of RBC aggregation for blood storage, the effect of the plasma factor was slightly stronger than that of the cellular factor. Through the present study, the critical shear stress as a new measure of RBC aggregation may help to monitor and control the quality of blood storage. RBC (dpeaa)DE-He213 aggregation (dpeaa)DE-He213 blood (dpeaa)DE-He213 storage (dpeaa)DE-He213 critical shear stress (dpeaa)DE-He213 Nam, Jeong-Hun verfasserin aut Lee, Byoung-Kwon verfasserin aut Suh, Jang-Soo verfasserin aut Shin, Sehyun verfasserin aut Enthalten in Korea-Australia Rheology Journal Korean Society of Rheology, Australian Society of Rheology, 2011 23(2011), 2 vom: Juni, Seite 67-70 (DE-627)SPR031694004 nnns volume:23 year:2011 number:2 month:06 pages:67-70 https://dx.doi.org/10.1007/s13367-011-0009-3 lizenzpflichtig Volltext GBV_USEFLAG_A SYSFLAG_A GBV_SPRINGER GBV_ILN_20 GBV_ILN_21 GBV_ILN_70 AR 23 2011 2 06 67-70 |
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10.1007/s13367-011-0009-3 doi (DE-627)SPR031694160 (SPR)s13367-011-0009-3-e DE-627 ger DE-627 rakwb eng Lim, Hyun-Jung verfasserin aut Alteration of red blood cell aggregation during blood storage 2011 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Abstract Even though the trade-off between the benefits and risks of blood transfusion has been discussed for the last several decades, it requires further understanding of the rheological changes in stored blood that include the alteration of red blood cell (RBC) aggregation. The RBC aggregation of stored blood in its autologous plasma was monitored through the storage period (35 days). The critical shear stress, as a measure of RBC aggregation, was determined by using a microfluidic aggregometer. Blood was processed into a blood bag containing the anticoagulant CPDA1 and stored at 4°C. It was subjected to assays after zero, seven, 14, and 35 days. The critical shear stress for stored blood did not change up to 14 days of storage but exhibited a significant decrease after 35 days of storage. These results were identical to those of the conventional aggregation index (AI). Also, in the alteration of RBC aggregation for blood storage, the effect of the plasma factor was slightly stronger than that of the cellular factor. Through the present study, the critical shear stress as a new measure of RBC aggregation may help to monitor and control the quality of blood storage. RBC (dpeaa)DE-He213 aggregation (dpeaa)DE-He213 blood (dpeaa)DE-He213 storage (dpeaa)DE-He213 critical shear stress (dpeaa)DE-He213 Nam, Jeong-Hun verfasserin aut Lee, Byoung-Kwon verfasserin aut Suh, Jang-Soo verfasserin aut Shin, Sehyun verfasserin aut Enthalten in Korea-Australia Rheology Journal Korean Society of Rheology, Australian Society of Rheology, 2011 23(2011), 2 vom: Juni, Seite 67-70 (DE-627)SPR031694004 nnns volume:23 year:2011 number:2 month:06 pages:67-70 https://dx.doi.org/10.1007/s13367-011-0009-3 lizenzpflichtig Volltext GBV_USEFLAG_A SYSFLAG_A GBV_SPRINGER GBV_ILN_20 GBV_ILN_21 GBV_ILN_70 AR 23 2011 2 06 67-70 |
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10.1007/s13367-011-0009-3 doi (DE-627)SPR031694160 (SPR)s13367-011-0009-3-e DE-627 ger DE-627 rakwb eng Lim, Hyun-Jung verfasserin aut Alteration of red blood cell aggregation during blood storage 2011 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Abstract Even though the trade-off between the benefits and risks of blood transfusion has been discussed for the last several decades, it requires further understanding of the rheological changes in stored blood that include the alteration of red blood cell (RBC) aggregation. The RBC aggregation of stored blood in its autologous plasma was monitored through the storage period (35 days). The critical shear stress, as a measure of RBC aggregation, was determined by using a microfluidic aggregometer. Blood was processed into a blood bag containing the anticoagulant CPDA1 and stored at 4°C. It was subjected to assays after zero, seven, 14, and 35 days. The critical shear stress for stored blood did not change up to 14 days of storage but exhibited a significant decrease after 35 days of storage. These results were identical to those of the conventional aggregation index (AI). Also, in the alteration of RBC aggregation for blood storage, the effect of the plasma factor was slightly stronger than that of the cellular factor. Through the present study, the critical shear stress as a new measure of RBC aggregation may help to monitor and control the quality of blood storage. RBC (dpeaa)DE-He213 aggregation (dpeaa)DE-He213 blood (dpeaa)DE-He213 storage (dpeaa)DE-He213 critical shear stress (dpeaa)DE-He213 Nam, Jeong-Hun verfasserin aut Lee, Byoung-Kwon verfasserin aut Suh, Jang-Soo verfasserin aut Shin, Sehyun verfasserin aut Enthalten in Korea-Australia Rheology Journal Korean Society of Rheology, Australian Society of Rheology, 2011 23(2011), 2 vom: Juni, Seite 67-70 (DE-627)SPR031694004 nnns volume:23 year:2011 number:2 month:06 pages:67-70 https://dx.doi.org/10.1007/s13367-011-0009-3 lizenzpflichtig Volltext GBV_USEFLAG_A SYSFLAG_A GBV_SPRINGER GBV_ILN_20 GBV_ILN_21 GBV_ILN_70 AR 23 2011 2 06 67-70 |
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10.1007/s13367-011-0009-3 doi (DE-627)SPR031694160 (SPR)s13367-011-0009-3-e DE-627 ger DE-627 rakwb eng Lim, Hyun-Jung verfasserin aut Alteration of red blood cell aggregation during blood storage 2011 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Abstract Even though the trade-off between the benefits and risks of blood transfusion has been discussed for the last several decades, it requires further understanding of the rheological changes in stored blood that include the alteration of red blood cell (RBC) aggregation. The RBC aggregation of stored blood in its autologous plasma was monitored through the storage period (35 days). The critical shear stress, as a measure of RBC aggregation, was determined by using a microfluidic aggregometer. Blood was processed into a blood bag containing the anticoagulant CPDA1 and stored at 4°C. It was subjected to assays after zero, seven, 14, and 35 days. The critical shear stress for stored blood did not change up to 14 days of storage but exhibited a significant decrease after 35 days of storage. These results were identical to those of the conventional aggregation index (AI). Also, in the alteration of RBC aggregation for blood storage, the effect of the plasma factor was slightly stronger than that of the cellular factor. Through the present study, the critical shear stress as a new measure of RBC aggregation may help to monitor and control the quality of blood storage. RBC (dpeaa)DE-He213 aggregation (dpeaa)DE-He213 blood (dpeaa)DE-He213 storage (dpeaa)DE-He213 critical shear stress (dpeaa)DE-He213 Nam, Jeong-Hun verfasserin aut Lee, Byoung-Kwon verfasserin aut Suh, Jang-Soo verfasserin aut Shin, Sehyun verfasserin aut Enthalten in Korea-Australia Rheology Journal Korean Society of Rheology, Australian Society of Rheology, 2011 23(2011), 2 vom: Juni, Seite 67-70 (DE-627)SPR031694004 nnns volume:23 year:2011 number:2 month:06 pages:67-70 https://dx.doi.org/10.1007/s13367-011-0009-3 lizenzpflichtig Volltext GBV_USEFLAG_A SYSFLAG_A GBV_SPRINGER GBV_ILN_20 GBV_ILN_21 GBV_ILN_70 AR 23 2011 2 06 67-70 |
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Abstract Even though the trade-off between the benefits and risks of blood transfusion has been discussed for the last several decades, it requires further understanding of the rheological changes in stored blood that include the alteration of red blood cell (RBC) aggregation. The RBC aggregation of stored blood in its autologous plasma was monitored through the storage period (35 days). The critical shear stress, as a measure of RBC aggregation, was determined by using a microfluidic aggregometer. Blood was processed into a blood bag containing the anticoagulant CPDA1 and stored at 4°C. It was subjected to assays after zero, seven, 14, and 35 days. The critical shear stress for stored blood did not change up to 14 days of storage but exhibited a significant decrease after 35 days of storage. These results were identical to those of the conventional aggregation index (AI). Also, in the alteration of RBC aggregation for blood storage, the effect of the plasma factor was slightly stronger than that of the cellular factor. Through the present study, the critical shear stress as a new measure of RBC aggregation may help to monitor and control the quality of blood storage. |
abstractGer |
Abstract Even though the trade-off between the benefits and risks of blood transfusion has been discussed for the last several decades, it requires further understanding of the rheological changes in stored blood that include the alteration of red blood cell (RBC) aggregation. The RBC aggregation of stored blood in its autologous plasma was monitored through the storage period (35 days). The critical shear stress, as a measure of RBC aggregation, was determined by using a microfluidic aggregometer. Blood was processed into a blood bag containing the anticoagulant CPDA1 and stored at 4°C. It was subjected to assays after zero, seven, 14, and 35 days. The critical shear stress for stored blood did not change up to 14 days of storage but exhibited a significant decrease after 35 days of storage. These results were identical to those of the conventional aggregation index (AI). Also, in the alteration of RBC aggregation for blood storage, the effect of the plasma factor was slightly stronger than that of the cellular factor. Through the present study, the critical shear stress as a new measure of RBC aggregation may help to monitor and control the quality of blood storage. |
abstract_unstemmed |
Abstract Even though the trade-off between the benefits and risks of blood transfusion has been discussed for the last several decades, it requires further understanding of the rheological changes in stored blood that include the alteration of red blood cell (RBC) aggregation. The RBC aggregation of stored blood in its autologous plasma was monitored through the storage period (35 days). The critical shear stress, as a measure of RBC aggregation, was determined by using a microfluidic aggregometer. Blood was processed into a blood bag containing the anticoagulant CPDA1 and stored at 4°C. It was subjected to assays after zero, seven, 14, and 35 days. The critical shear stress for stored blood did not change up to 14 days of storage but exhibited a significant decrease after 35 days of storage. These results were identical to those of the conventional aggregation index (AI). Also, in the alteration of RBC aggregation for blood storage, the effect of the plasma factor was slightly stronger than that of the cellular factor. Through the present study, the critical shear stress as a new measure of RBC aggregation may help to monitor and control the quality of blood storage. |
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Alteration of red blood cell aggregation during blood storage |
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https://dx.doi.org/10.1007/s13367-011-0009-3 |
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Nam, Jeong-Hun Lee, Byoung-Kwon Suh, Jang-Soo Shin, Sehyun |
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Nam, Jeong-Hun Lee, Byoung-Kwon Suh, Jang-Soo Shin, Sehyun |
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10.1007/s13367-011-0009-3 |
up_date |
2024-07-04T00:52:57.985Z |
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