Hemotoxic effects of cadmium in normal and protein malnourished rats
Abstract Cadmium is chemically related to zinc and found wherever zinc occurs in nature. Cadmium is emitted to air and water by mines, metal foundries, viz. brass and industries using Cadmium in alkaline accumulators, alloys, paints and plastics. Cadmium exposure results in increase of concentration...
Ausführliche Beschreibung
Gespeichert in:
| Autor*in: |
Husain, Syed Saleem [verfasserIn] |
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E-Artikel |
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| Sprache: |
Englisch |
| Erschienen: |
2015 |
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| Schlagwörter: |
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| Übergeordnetes Werk: |
Enthalten in: Toxicology and Environmental Health Sciences - Korean Society of Environmental Risk Assessment and Health Science, 2011, 7(2015), 2 vom: Juni, Seite 129-135 |
|---|---|
| Übergeordnetes Werk: |
volume:7 ; year:2015 ; number:2 ; month:06 ; pages:129-135 |
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|---|
| DOI / URN: |
10.1007/s13530-015-0231-3 |
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SPR031728375 |
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| 520 | |a Abstract Cadmium is chemically related to zinc and found wherever zinc occurs in nature. Cadmium is emitted to air and water by mines, metal foundries, viz. brass and industries using Cadmium in alkaline accumulators, alloys, paints and plastics. Cadmium exposure results in increase of concentration of a protein, called metallothionein, which plays an important role in detoxification of heavy metals. In persons not exposed to high amounts of cadmium, the concentration of cadmium in blood, bound mainly to red blood cells, is very small, less than 1 µg/100 mL whole blood. Gontzea and $ Popescu^{1} $ revealed that rats reared on low protein (casein 8.8%) diet were more susceptible to the adverse effects (blood and liver enzyme parameters) of injected Cd, than control given a diet with 17.8% casein. The present study was conducted on rats maintained on normal (21% protein) and protein malnourished (8% protein) diets. Exposure to cadmium in growing rats induced structural anomalies in the erythrocytes and leukocytes. Microcytic hypochromic anemia with erythrocytopenia and leukocytopenia were evident. Protein malnutrition appears to enhance the vulnerability of the animals to these changes. | ||
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10.1007/s13530-015-0231-3 doi (DE-627)SPR031728375 (SPR)s13530-015-0231-3-e DE-627 ger DE-627 rakwb eng Husain, Syed Saleem verfasserin aut Hemotoxic effects of cadmium in normal and protein malnourished rats 2015 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Abstract Cadmium is chemically related to zinc and found wherever zinc occurs in nature. Cadmium is emitted to air and water by mines, metal foundries, viz. brass and industries using Cadmium in alkaline accumulators, alloys, paints and plastics. Cadmium exposure results in increase of concentration of a protein, called metallothionein, which plays an important role in detoxification of heavy metals. In persons not exposed to high amounts of cadmium, the concentration of cadmium in blood, bound mainly to red blood cells, is very small, less than 1 µg/100 mL whole blood. Gontzea and $ Popescu^{1} $ revealed that rats reared on low protein (casein 8.8%) diet were more susceptible to the adverse effects (blood and liver enzyme parameters) of injected Cd, than control given a diet with 17.8% casein. The present study was conducted on rats maintained on normal (21% protein) and protein malnourished (8% protein) diets. Exposure to cadmium in growing rats induced structural anomalies in the erythrocytes and leukocytes. Microcytic hypochromic anemia with erythrocytopenia and leukocytopenia were evident. Protein malnutrition appears to enhance the vulnerability of the animals to these changes. Cadmium toxicity (dpeaa)DE-He213 Protein malnourishment (dpeaa)DE-He213 Hematology (dpeaa)DE-He213 Enthalten in Toxicology and Environmental Health Sciences Korean Society of Environmental Risk Assessment and Health Science, 2011 7(2015), 2 vom: Juni, Seite 129-135 (DE-627)SPR031726593 nnns volume:7 year:2015 number:2 month:06 pages:129-135 https://dx.doi.org/10.1007/s13530-015-0231-3 lizenzpflichtig Volltext GBV_USEFLAG_A SYSFLAG_A GBV_SPRINGER AR 7 2015 2 06 129-135 |
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10.1007/s13530-015-0231-3 doi (DE-627)SPR031728375 (SPR)s13530-015-0231-3-e DE-627 ger DE-627 rakwb eng Husain, Syed Saleem verfasserin aut Hemotoxic effects of cadmium in normal and protein malnourished rats 2015 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Abstract Cadmium is chemically related to zinc and found wherever zinc occurs in nature. Cadmium is emitted to air and water by mines, metal foundries, viz. brass and industries using Cadmium in alkaline accumulators, alloys, paints and plastics. Cadmium exposure results in increase of concentration of a protein, called metallothionein, which plays an important role in detoxification of heavy metals. In persons not exposed to high amounts of cadmium, the concentration of cadmium in blood, bound mainly to red blood cells, is very small, less than 1 µg/100 mL whole blood. Gontzea and $ Popescu^{1} $ revealed that rats reared on low protein (casein 8.8%) diet were more susceptible to the adverse effects (blood and liver enzyme parameters) of injected Cd, than control given a diet with 17.8% casein. The present study was conducted on rats maintained on normal (21% protein) and protein malnourished (8% protein) diets. Exposure to cadmium in growing rats induced structural anomalies in the erythrocytes and leukocytes. Microcytic hypochromic anemia with erythrocytopenia and leukocytopenia were evident. Protein malnutrition appears to enhance the vulnerability of the animals to these changes. Cadmium toxicity (dpeaa)DE-He213 Protein malnourishment (dpeaa)DE-He213 Hematology (dpeaa)DE-He213 Enthalten in Toxicology and Environmental Health Sciences Korean Society of Environmental Risk Assessment and Health Science, 2011 7(2015), 2 vom: Juni, Seite 129-135 (DE-627)SPR031726593 nnns volume:7 year:2015 number:2 month:06 pages:129-135 https://dx.doi.org/10.1007/s13530-015-0231-3 lizenzpflichtig Volltext GBV_USEFLAG_A SYSFLAG_A GBV_SPRINGER AR 7 2015 2 06 129-135 |
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10.1007/s13530-015-0231-3 doi (DE-627)SPR031728375 (SPR)s13530-015-0231-3-e DE-627 ger DE-627 rakwb eng Husain, Syed Saleem verfasserin aut Hemotoxic effects of cadmium in normal and protein malnourished rats 2015 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Abstract Cadmium is chemically related to zinc and found wherever zinc occurs in nature. Cadmium is emitted to air and water by mines, metal foundries, viz. brass and industries using Cadmium in alkaline accumulators, alloys, paints and plastics. Cadmium exposure results in increase of concentration of a protein, called metallothionein, which plays an important role in detoxification of heavy metals. In persons not exposed to high amounts of cadmium, the concentration of cadmium in blood, bound mainly to red blood cells, is very small, less than 1 µg/100 mL whole blood. Gontzea and $ Popescu^{1} $ revealed that rats reared on low protein (casein 8.8%) diet were more susceptible to the adverse effects (blood and liver enzyme parameters) of injected Cd, than control given a diet with 17.8% casein. The present study was conducted on rats maintained on normal (21% protein) and protein malnourished (8% protein) diets. Exposure to cadmium in growing rats induced structural anomalies in the erythrocytes and leukocytes. Microcytic hypochromic anemia with erythrocytopenia and leukocytopenia were evident. Protein malnutrition appears to enhance the vulnerability of the animals to these changes. Cadmium toxicity (dpeaa)DE-He213 Protein malnourishment (dpeaa)DE-He213 Hematology (dpeaa)DE-He213 Enthalten in Toxicology and Environmental Health Sciences Korean Society of Environmental Risk Assessment and Health Science, 2011 7(2015), 2 vom: Juni, Seite 129-135 (DE-627)SPR031726593 nnns volume:7 year:2015 number:2 month:06 pages:129-135 https://dx.doi.org/10.1007/s13530-015-0231-3 lizenzpflichtig Volltext GBV_USEFLAG_A SYSFLAG_A GBV_SPRINGER AR 7 2015 2 06 129-135 |
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10.1007/s13530-015-0231-3 doi (DE-627)SPR031728375 (SPR)s13530-015-0231-3-e DE-627 ger DE-627 rakwb eng Husain, Syed Saleem verfasserin aut Hemotoxic effects of cadmium in normal and protein malnourished rats 2015 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Abstract Cadmium is chemically related to zinc and found wherever zinc occurs in nature. Cadmium is emitted to air and water by mines, metal foundries, viz. brass and industries using Cadmium in alkaline accumulators, alloys, paints and plastics. Cadmium exposure results in increase of concentration of a protein, called metallothionein, which plays an important role in detoxification of heavy metals. In persons not exposed to high amounts of cadmium, the concentration of cadmium in blood, bound mainly to red blood cells, is very small, less than 1 µg/100 mL whole blood. Gontzea and $ Popescu^{1} $ revealed that rats reared on low protein (casein 8.8%) diet were more susceptible to the adverse effects (blood and liver enzyme parameters) of injected Cd, than control given a diet with 17.8% casein. The present study was conducted on rats maintained on normal (21% protein) and protein malnourished (8% protein) diets. Exposure to cadmium in growing rats induced structural anomalies in the erythrocytes and leukocytes. Microcytic hypochromic anemia with erythrocytopenia and leukocytopenia were evident. Protein malnutrition appears to enhance the vulnerability of the animals to these changes. Cadmium toxicity (dpeaa)DE-He213 Protein malnourishment (dpeaa)DE-He213 Hematology (dpeaa)DE-He213 Enthalten in Toxicology and Environmental Health Sciences Korean Society of Environmental Risk Assessment and Health Science, 2011 7(2015), 2 vom: Juni, Seite 129-135 (DE-627)SPR031726593 nnns volume:7 year:2015 number:2 month:06 pages:129-135 https://dx.doi.org/10.1007/s13530-015-0231-3 lizenzpflichtig Volltext GBV_USEFLAG_A SYSFLAG_A GBV_SPRINGER AR 7 2015 2 06 129-135 |
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Abstract Cadmium is chemically related to zinc and found wherever zinc occurs in nature. Cadmium is emitted to air and water by mines, metal foundries, viz. brass and industries using Cadmium in alkaline accumulators, alloys, paints and plastics. Cadmium exposure results in increase of concentration of a protein, called metallothionein, which plays an important role in detoxification of heavy metals. In persons not exposed to high amounts of cadmium, the concentration of cadmium in blood, bound mainly to red blood cells, is very small, less than 1 µg/100 mL whole blood. Gontzea and $ Popescu^{1} $ revealed that rats reared on low protein (casein 8.8%) diet were more susceptible to the adverse effects (blood and liver enzyme parameters) of injected Cd, than control given a diet with 17.8% casein. The present study was conducted on rats maintained on normal (21% protein) and protein malnourished (8% protein) diets. Exposure to cadmium in growing rats induced structural anomalies in the erythrocytes and leukocytes. Microcytic hypochromic anemia with erythrocytopenia and leukocytopenia were evident. Protein malnutrition appears to enhance the vulnerability of the animals to these changes. |
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Abstract Cadmium is chemically related to zinc and found wherever zinc occurs in nature. Cadmium is emitted to air and water by mines, metal foundries, viz. brass and industries using Cadmium in alkaline accumulators, alloys, paints and plastics. Cadmium exposure results in increase of concentration of a protein, called metallothionein, which plays an important role in detoxification of heavy metals. In persons not exposed to high amounts of cadmium, the concentration of cadmium in blood, bound mainly to red blood cells, is very small, less than 1 µg/100 mL whole blood. Gontzea and $ Popescu^{1} $ revealed that rats reared on low protein (casein 8.8%) diet were more susceptible to the adverse effects (blood and liver enzyme parameters) of injected Cd, than control given a diet with 17.8% casein. The present study was conducted on rats maintained on normal (21% protein) and protein malnourished (8% protein) diets. Exposure to cadmium in growing rats induced structural anomalies in the erythrocytes and leukocytes. Microcytic hypochromic anemia with erythrocytopenia and leukocytopenia were evident. Protein malnutrition appears to enhance the vulnerability of the animals to these changes. |
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Abstract Cadmium is chemically related to zinc and found wherever zinc occurs in nature. Cadmium is emitted to air and water by mines, metal foundries, viz. brass and industries using Cadmium in alkaline accumulators, alloys, paints and plastics. Cadmium exposure results in increase of concentration of a protein, called metallothionein, which plays an important role in detoxification of heavy metals. In persons not exposed to high amounts of cadmium, the concentration of cadmium in blood, bound mainly to red blood cells, is very small, less than 1 µg/100 mL whole blood. Gontzea and $ Popescu^{1} $ revealed that rats reared on low protein (casein 8.8%) diet were more susceptible to the adverse effects (blood and liver enzyme parameters) of injected Cd, than control given a diet with 17.8% casein. The present study was conducted on rats maintained on normal (21% protein) and protein malnourished (8% protein) diets. Exposure to cadmium in growing rats induced structural anomalies in the erythrocytes and leukocytes. Microcytic hypochromic anemia with erythrocytopenia and leukocytopenia were evident. Protein malnutrition appears to enhance the vulnerability of the animals to these changes. |
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<?xml version="1.0" encoding="UTF-8"?><collection xmlns="http://www.loc.gov/MARC21/slim"><record><leader>01000caa a22002652 4500</leader><controlfield tag="001">SPR031728375</controlfield><controlfield tag="003">DE-627</controlfield><controlfield tag="005">20201125152602.0</controlfield><controlfield tag="007">cr uuu---uuuuu</controlfield><controlfield tag="008">201007s2015 xx |||||o 00| ||eng c</controlfield><datafield tag="024" ind1="7" ind2=" "><subfield code="a">10.1007/s13530-015-0231-3</subfield><subfield code="2">doi</subfield></datafield><datafield tag="035" ind1=" " ind2=" "><subfield code="a">(DE-627)SPR031728375</subfield></datafield><datafield tag="035" ind1=" " ind2=" "><subfield code="a">(SPR)s13530-015-0231-3-e</subfield></datafield><datafield tag="040" ind1=" " ind2=" "><subfield code="a">DE-627</subfield><subfield code="b">ger</subfield><subfield code="c">DE-627</subfield><subfield code="e">rakwb</subfield></datafield><datafield tag="041" ind1=" " ind2=" "><subfield code="a">eng</subfield></datafield><datafield tag="100" ind1="1" ind2=" "><subfield code="a">Husain, Syed Saleem</subfield><subfield code="e">verfasserin</subfield><subfield code="4">aut</subfield></datafield><datafield tag="245" ind1="1" ind2="0"><subfield code="a">Hemotoxic effects of cadmium in normal and protein malnourished rats</subfield></datafield><datafield tag="264" ind1=" " ind2="1"><subfield code="c">2015</subfield></datafield><datafield tag="336" ind1=" " ind2=" "><subfield code="a">Text</subfield><subfield code="b">txt</subfield><subfield code="2">rdacontent</subfield></datafield><datafield tag="337" ind1=" " ind2=" "><subfield code="a">Computermedien</subfield><subfield code="b">c</subfield><subfield code="2">rdamedia</subfield></datafield><datafield tag="338" ind1=" " ind2=" "><subfield code="a">Online-Ressource</subfield><subfield code="b">cr</subfield><subfield code="2">rdacarrier</subfield></datafield><datafield tag="520" ind1=" " ind2=" "><subfield code="a">Abstract Cadmium is chemically related to zinc and found wherever zinc occurs in nature. Cadmium is emitted to air and water by mines, metal foundries, viz. brass and industries using Cadmium in alkaline accumulators, alloys, paints and plastics. Cadmium exposure results in increase of concentration of a protein, called metallothionein, which plays an important role in detoxification of heavy metals. In persons not exposed to high amounts of cadmium, the concentration of cadmium in blood, bound mainly to red blood cells, is very small, less than 1 µg/100 mL whole blood. Gontzea and $ Popescu^{1} $ revealed that rats reared on low protein (casein 8.8%) diet were more susceptible to the adverse effects (blood and liver enzyme parameters) of injected Cd, than control given a diet with 17.8% casein. The present study was conducted on rats maintained on normal (21% protein) and protein malnourished (8% protein) diets. Exposure to cadmium in growing rats induced structural anomalies in the erythrocytes and leukocytes. Microcytic hypochromic anemia with erythrocytopenia and leukocytopenia were evident. Protein malnutrition appears to enhance the vulnerability of the animals to these changes.</subfield></datafield><datafield tag="650" ind1=" " ind2="4"><subfield code="a">Cadmium toxicity</subfield><subfield code="7">(dpeaa)DE-He213</subfield></datafield><datafield tag="650" ind1=" " ind2="4"><subfield code="a">Protein malnourishment</subfield><subfield code="7">(dpeaa)DE-He213</subfield></datafield><datafield tag="650" ind1=" " ind2="4"><subfield code="a">Hematology</subfield><subfield code="7">(dpeaa)DE-He213</subfield></datafield><datafield tag="773" ind1="0" ind2="8"><subfield code="i">Enthalten in</subfield><subfield code="t">Toxicology and Environmental Health Sciences</subfield><subfield code="d">Korean Society of Environmental Risk Assessment and Health Science, 2011</subfield><subfield code="g">7(2015), 2 vom: Juni, Seite 129-135</subfield><subfield code="w">(DE-627)SPR031726593</subfield><subfield code="7">nnns</subfield></datafield><datafield tag="773" ind1="1" ind2="8"><subfield code="g">volume:7</subfield><subfield code="g">year:2015</subfield><subfield code="g">number:2</subfield><subfield code="g">month:06</subfield><subfield code="g">pages:129-135</subfield></datafield><datafield tag="856" ind1="4" ind2="0"><subfield code="u">https://dx.doi.org/10.1007/s13530-015-0231-3</subfield><subfield code="z">lizenzpflichtig</subfield><subfield code="3">Volltext</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_USEFLAG_A</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">SYSFLAG_A</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_SPRINGER</subfield></datafield><datafield tag="951" ind1=" " ind2=" "><subfield code="a">AR</subfield></datafield><datafield tag="952" ind1=" " ind2=" "><subfield code="d">7</subfield><subfield code="j">2015</subfield><subfield code="e">2</subfield><subfield code="c">06</subfield><subfield code="h">129-135</subfield></datafield></record></collection>
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