Whole lung irradiation in pediatric patients using helical tomotherapy to minimize cardiac, breast, and thyroid dose
Objective The purpose of this study is to determine whether the use of helical tomotherapy can reduce dose to the heart, breast tissue, and thyroid gland in children receiving whole lung irradiation (WLI). Methods Computed tomography simulation scans from nine pediatric patients previously treated w...
Ausführliche Beschreibung
Gespeichert in:
| Autor*in: |
Siddiqui, Farzan [verfasserIn] Mathews, Thomas [verfasserIn] Teh, Bin S. [verfasserIn] Kalapurakal, John A. [verfasserIn] Butler, E. Brian [verfasserIn] Chintagumpala, Murali [verfasserIn] Paulino, Arnold C. [verfasserIn] |
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| Format: |
E-Artikel |
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| Sprache: |
Englisch |
| Erschienen: |
2012 |
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| Schlagwörter: |
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| Übergeordnetes Werk: |
Enthalten in: Journal of radiation oncology - Berlin : Springer, 2012, 2(2012), 1 vom: 19. Juli, Seite 49-53 |
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| Übergeordnetes Werk: |
volume:2 ; year:2012 ; number:1 ; day:19 ; month:07 ; pages:49-53 |
| Links: |
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| DOI / URN: |
10.1007/s13566-012-0056-5 |
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| Katalog-ID: |
SPR031809723 |
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| 520 | |a Objective The purpose of this study is to determine whether the use of helical tomotherapy can reduce dose to the heart, breast tissue, and thyroid gland in children receiving whole lung irradiation (WLI). Methods Computed tomography simulation scans from nine pediatric patients previously treated with WLI were used for this dosimetry study. Each scan was alternatively planned using helical tomotherapy to minimize dose to surrounding critical structures. The clinical target volume (CTV) included both lungs. The ribs and spine in proximity to the lungs were included in the CTV to minimize bone asymmetry resulting from partial irradiation. The planning target volume (PTV) included the CTV with a 0.8-cm margin. The following structures were contoured: right atrium, left atrium, right ventricle, left ventricle, right and left breast, thyroid gland, and the humeral heads. Median dose (Dmed), minimum dose (Dmin), and maximum dose (Dmax) for the PTV, CTV, heart chambers, thyroid gland, right and left breast as well as right and left humeral heads were also obtained. Results The median PTV receiving the prescription dose was 97 %, with PTVs ranging from 95 to 99 %. The average Dmed for each of the four chambers of the heart ranged from 37 to 55 % of the prescription dose. The average Dmed for the breasts ranged from 88 to 95 % while for the thyroid gland was 10 % of the prescription dose. Conclusion Helical tomotherapy can minimize the radiation dose delivered to nontarget organs such as the heart, breasts, and thyroid gland. | ||
| 650 | 4 | |a Whole lung irradiation |7 (dpeaa)DE-He213 | |
| 650 | 4 | |a Pediatric cancer |7 (dpeaa)DE-He213 | |
| 650 | 4 | |a Wilms’ tumor |7 (dpeaa)DE-He213 | |
| 650 | 4 | |a Ewing’s sarcoma |7 (dpeaa)DE-He213 | |
| 650 | 4 | |a Lung metastasis |7 (dpeaa)DE-He213 | |
| 700 | 1 | |a Mathews, Thomas |e verfasserin |4 aut | |
| 700 | 1 | |a Teh, Bin S. |e verfasserin |4 aut | |
| 700 | 1 | |a Kalapurakal, John A. |e verfasserin |4 aut | |
| 700 | 1 | |a Butler, E. Brian |e verfasserin |4 aut | |
| 700 | 1 | |a Chintagumpala, Murali |e verfasserin |4 aut | |
| 700 | 1 | |a Paulino, Arnold C. |e verfasserin |4 aut | |
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10.1007/s13566-012-0056-5 doi (DE-627)SPR031809723 (SPR)s13566-012-0056-5-e DE-627 ger DE-627 rakwb eng 610 ASE Siddiqui, Farzan verfasserin aut Whole lung irradiation in pediatric patients using helical tomotherapy to minimize cardiac, breast, and thyroid dose 2012 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Objective The purpose of this study is to determine whether the use of helical tomotherapy can reduce dose to the heart, breast tissue, and thyroid gland in children receiving whole lung irradiation (WLI). Methods Computed tomography simulation scans from nine pediatric patients previously treated with WLI were used for this dosimetry study. Each scan was alternatively planned using helical tomotherapy to minimize dose to surrounding critical structures. The clinical target volume (CTV) included both lungs. The ribs and spine in proximity to the lungs were included in the CTV to minimize bone asymmetry resulting from partial irradiation. The planning target volume (PTV) included the CTV with a 0.8-cm margin. The following structures were contoured: right atrium, left atrium, right ventricle, left ventricle, right and left breast, thyroid gland, and the humeral heads. Median dose (Dmed), minimum dose (Dmin), and maximum dose (Dmax) for the PTV, CTV, heart chambers, thyroid gland, right and left breast as well as right and left humeral heads were also obtained. Results The median PTV receiving the prescription dose was 97 %, with PTVs ranging from 95 to 99 %. The average Dmed for each of the four chambers of the heart ranged from 37 to 55 % of the prescription dose. The average Dmed for the breasts ranged from 88 to 95 % while for the thyroid gland was 10 % of the prescription dose. Conclusion Helical tomotherapy can minimize the radiation dose delivered to nontarget organs such as the heart, breasts, and thyroid gland. Whole lung irradiation (dpeaa)DE-He213 Pediatric cancer (dpeaa)DE-He213 Wilms’ tumor (dpeaa)DE-He213 Ewing’s sarcoma (dpeaa)DE-He213 Lung metastasis (dpeaa)DE-He213 Mathews, Thomas verfasserin aut Teh, Bin S. verfasserin aut Kalapurakal, John A. verfasserin aut Butler, E. Brian verfasserin aut Chintagumpala, Murali verfasserin aut Paulino, Arnold C. verfasserin aut Enthalten in Journal of radiation oncology Berlin : Springer, 2012 2(2012), 1 vom: 19. Juli, Seite 49-53 (DE-627)718611233 (DE-600)2660511-9 1948-7908 nnns volume:2 year:2012 number:1 day:19 month:07 pages:49-53 https://dx.doi.org/10.1007/s13566-012-0056-5 lizenzpflichtig Volltext GBV_USEFLAG_A SYSFLAG_A GBV_SPRINGER SSG-OLC-PHA GBV_ILN_11 GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_32 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_70 GBV_ILN_73 GBV_ILN_74 GBV_ILN_90 GBV_ILN_95 GBV_ILN_100 GBV_ILN_101 GBV_ILN_105 GBV_ILN_110 GBV_ILN_120 GBV_ILN_138 GBV_ILN_150 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_171 GBV_ILN_187 GBV_ILN_213 GBV_ILN_224 GBV_ILN_230 GBV_ILN_250 GBV_ILN_281 GBV_ILN_285 GBV_ILN_293 GBV_ILN_370 GBV_ILN_602 GBV_ILN_636 GBV_ILN_702 GBV_ILN_2001 GBV_ILN_2003 GBV_ILN_2004 GBV_ILN_2005 GBV_ILN_2006 GBV_ILN_2007 GBV_ILN_2008 GBV_ILN_2009 GBV_ILN_2010 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2015 GBV_ILN_2020 GBV_ILN_2021 GBV_ILN_2025 GBV_ILN_2026 GBV_ILN_2027 GBV_ILN_2031 GBV_ILN_2034 GBV_ILN_2037 GBV_ILN_2038 GBV_ILN_2039 GBV_ILN_2044 GBV_ILN_2048 GBV_ILN_2049 GBV_ILN_2050 GBV_ILN_2055 GBV_ILN_2057 GBV_ILN_2059 GBV_ILN_2061 GBV_ILN_2064 GBV_ILN_2065 GBV_ILN_2068 GBV_ILN_2070 GBV_ILN_2086 GBV_ILN_2088 GBV_ILN_2093 GBV_ILN_2106 GBV_ILN_2107 GBV_ILN_2108 GBV_ILN_2110 GBV_ILN_2111 GBV_ILN_2112 GBV_ILN_2113 GBV_ILN_2116 GBV_ILN_2118 GBV_ILN_2119 GBV_ILN_2122 GBV_ILN_2129 GBV_ILN_2143 GBV_ILN_2144 GBV_ILN_2147 GBV_ILN_2148 GBV_ILN_2152 GBV_ILN_2153 GBV_ILN_2188 GBV_ILN_2232 GBV_ILN_2336 GBV_ILN_2446 GBV_ILN_2470 GBV_ILN_2472 GBV_ILN_2507 GBV_ILN_2522 GBV_ILN_2548 GBV_ILN_4035 GBV_ILN_4037 GBV_ILN_4046 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4242 GBV_ILN_4246 GBV_ILN_4249 GBV_ILN_4251 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4326 GBV_ILN_4333 GBV_ILN_4334 GBV_ILN_4335 GBV_ILN_4336 GBV_ILN_4338 GBV_ILN_4393 GBV_ILN_4700 AR 2 2012 1 19 07 49-53 |
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10.1007/s13566-012-0056-5 doi (DE-627)SPR031809723 (SPR)s13566-012-0056-5-e DE-627 ger DE-627 rakwb eng 610 ASE Siddiqui, Farzan verfasserin aut Whole lung irradiation in pediatric patients using helical tomotherapy to minimize cardiac, breast, and thyroid dose 2012 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Objective The purpose of this study is to determine whether the use of helical tomotherapy can reduce dose to the heart, breast tissue, and thyroid gland in children receiving whole lung irradiation (WLI). Methods Computed tomography simulation scans from nine pediatric patients previously treated with WLI were used for this dosimetry study. Each scan was alternatively planned using helical tomotherapy to minimize dose to surrounding critical structures. The clinical target volume (CTV) included both lungs. The ribs and spine in proximity to the lungs were included in the CTV to minimize bone asymmetry resulting from partial irradiation. The planning target volume (PTV) included the CTV with a 0.8-cm margin. The following structures were contoured: right atrium, left atrium, right ventricle, left ventricle, right and left breast, thyroid gland, and the humeral heads. Median dose (Dmed), minimum dose (Dmin), and maximum dose (Dmax) for the PTV, CTV, heart chambers, thyroid gland, right and left breast as well as right and left humeral heads were also obtained. Results The median PTV receiving the prescription dose was 97 %, with PTVs ranging from 95 to 99 %. The average Dmed for each of the four chambers of the heart ranged from 37 to 55 % of the prescription dose. The average Dmed for the breasts ranged from 88 to 95 % while for the thyroid gland was 10 % of the prescription dose. Conclusion Helical tomotherapy can minimize the radiation dose delivered to nontarget organs such as the heart, breasts, and thyroid gland. Whole lung irradiation (dpeaa)DE-He213 Pediatric cancer (dpeaa)DE-He213 Wilms’ tumor (dpeaa)DE-He213 Ewing’s sarcoma (dpeaa)DE-He213 Lung metastasis (dpeaa)DE-He213 Mathews, Thomas verfasserin aut Teh, Bin S. verfasserin aut Kalapurakal, John A. verfasserin aut Butler, E. Brian verfasserin aut Chintagumpala, Murali verfasserin aut Paulino, Arnold C. verfasserin aut Enthalten in Journal of radiation oncology Berlin : Springer, 2012 2(2012), 1 vom: 19. Juli, Seite 49-53 (DE-627)718611233 (DE-600)2660511-9 1948-7908 nnns volume:2 year:2012 number:1 day:19 month:07 pages:49-53 https://dx.doi.org/10.1007/s13566-012-0056-5 lizenzpflichtig Volltext GBV_USEFLAG_A SYSFLAG_A GBV_SPRINGER SSG-OLC-PHA GBV_ILN_11 GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_32 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_70 GBV_ILN_73 GBV_ILN_74 GBV_ILN_90 GBV_ILN_95 GBV_ILN_100 GBV_ILN_101 GBV_ILN_105 GBV_ILN_110 GBV_ILN_120 GBV_ILN_138 GBV_ILN_150 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_171 GBV_ILN_187 GBV_ILN_213 GBV_ILN_224 GBV_ILN_230 GBV_ILN_250 GBV_ILN_281 GBV_ILN_285 GBV_ILN_293 GBV_ILN_370 GBV_ILN_602 GBV_ILN_636 GBV_ILN_702 GBV_ILN_2001 GBV_ILN_2003 GBV_ILN_2004 GBV_ILN_2005 GBV_ILN_2006 GBV_ILN_2007 GBV_ILN_2008 GBV_ILN_2009 GBV_ILN_2010 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2015 GBV_ILN_2020 GBV_ILN_2021 GBV_ILN_2025 GBV_ILN_2026 GBV_ILN_2027 GBV_ILN_2031 GBV_ILN_2034 GBV_ILN_2037 GBV_ILN_2038 GBV_ILN_2039 GBV_ILN_2044 GBV_ILN_2048 GBV_ILN_2049 GBV_ILN_2050 GBV_ILN_2055 GBV_ILN_2057 GBV_ILN_2059 GBV_ILN_2061 GBV_ILN_2064 GBV_ILN_2065 GBV_ILN_2068 GBV_ILN_2070 GBV_ILN_2086 GBV_ILN_2088 GBV_ILN_2093 GBV_ILN_2106 GBV_ILN_2107 GBV_ILN_2108 GBV_ILN_2110 GBV_ILN_2111 GBV_ILN_2112 GBV_ILN_2113 GBV_ILN_2116 GBV_ILN_2118 GBV_ILN_2119 GBV_ILN_2122 GBV_ILN_2129 GBV_ILN_2143 GBV_ILN_2144 GBV_ILN_2147 GBV_ILN_2148 GBV_ILN_2152 GBV_ILN_2153 GBV_ILN_2188 GBV_ILN_2232 GBV_ILN_2336 GBV_ILN_2446 GBV_ILN_2470 GBV_ILN_2472 GBV_ILN_2507 GBV_ILN_2522 GBV_ILN_2548 GBV_ILN_4035 GBV_ILN_4037 GBV_ILN_4046 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4242 GBV_ILN_4246 GBV_ILN_4249 GBV_ILN_4251 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4326 GBV_ILN_4333 GBV_ILN_4334 GBV_ILN_4335 GBV_ILN_4336 GBV_ILN_4338 GBV_ILN_4393 GBV_ILN_4700 AR 2 2012 1 19 07 49-53 |
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10.1007/s13566-012-0056-5 doi (DE-627)SPR031809723 (SPR)s13566-012-0056-5-e DE-627 ger DE-627 rakwb eng 610 ASE Siddiqui, Farzan verfasserin aut Whole lung irradiation in pediatric patients using helical tomotherapy to minimize cardiac, breast, and thyroid dose 2012 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Objective The purpose of this study is to determine whether the use of helical tomotherapy can reduce dose to the heart, breast tissue, and thyroid gland in children receiving whole lung irradiation (WLI). Methods Computed tomography simulation scans from nine pediatric patients previously treated with WLI were used for this dosimetry study. Each scan was alternatively planned using helical tomotherapy to minimize dose to surrounding critical structures. The clinical target volume (CTV) included both lungs. The ribs and spine in proximity to the lungs were included in the CTV to minimize bone asymmetry resulting from partial irradiation. The planning target volume (PTV) included the CTV with a 0.8-cm margin. The following structures were contoured: right atrium, left atrium, right ventricle, left ventricle, right and left breast, thyroid gland, and the humeral heads. Median dose (Dmed), minimum dose (Dmin), and maximum dose (Dmax) for the PTV, CTV, heart chambers, thyroid gland, right and left breast as well as right and left humeral heads were also obtained. Results The median PTV receiving the prescription dose was 97 %, with PTVs ranging from 95 to 99 %. The average Dmed for each of the four chambers of the heart ranged from 37 to 55 % of the prescription dose. The average Dmed for the breasts ranged from 88 to 95 % while for the thyroid gland was 10 % of the prescription dose. Conclusion Helical tomotherapy can minimize the radiation dose delivered to nontarget organs such as the heart, breasts, and thyroid gland. Whole lung irradiation (dpeaa)DE-He213 Pediatric cancer (dpeaa)DE-He213 Wilms’ tumor (dpeaa)DE-He213 Ewing’s sarcoma (dpeaa)DE-He213 Lung metastasis (dpeaa)DE-He213 Mathews, Thomas verfasserin aut Teh, Bin S. verfasserin aut Kalapurakal, John A. verfasserin aut Butler, E. Brian verfasserin aut Chintagumpala, Murali verfasserin aut Paulino, Arnold C. verfasserin aut Enthalten in Journal of radiation oncology Berlin : Springer, 2012 2(2012), 1 vom: 19. Juli, Seite 49-53 (DE-627)718611233 (DE-600)2660511-9 1948-7908 nnns volume:2 year:2012 number:1 day:19 month:07 pages:49-53 https://dx.doi.org/10.1007/s13566-012-0056-5 lizenzpflichtig Volltext GBV_USEFLAG_A SYSFLAG_A GBV_SPRINGER SSG-OLC-PHA GBV_ILN_11 GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_32 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_70 GBV_ILN_73 GBV_ILN_74 GBV_ILN_90 GBV_ILN_95 GBV_ILN_100 GBV_ILN_101 GBV_ILN_105 GBV_ILN_110 GBV_ILN_120 GBV_ILN_138 GBV_ILN_150 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_171 GBV_ILN_187 GBV_ILN_213 GBV_ILN_224 GBV_ILN_230 GBV_ILN_250 GBV_ILN_281 GBV_ILN_285 GBV_ILN_293 GBV_ILN_370 GBV_ILN_602 GBV_ILN_636 GBV_ILN_702 GBV_ILN_2001 GBV_ILN_2003 GBV_ILN_2004 GBV_ILN_2005 GBV_ILN_2006 GBV_ILN_2007 GBV_ILN_2008 GBV_ILN_2009 GBV_ILN_2010 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2015 GBV_ILN_2020 GBV_ILN_2021 GBV_ILN_2025 GBV_ILN_2026 GBV_ILN_2027 GBV_ILN_2031 GBV_ILN_2034 GBV_ILN_2037 GBV_ILN_2038 GBV_ILN_2039 GBV_ILN_2044 GBV_ILN_2048 GBV_ILN_2049 GBV_ILN_2050 GBV_ILN_2055 GBV_ILN_2057 GBV_ILN_2059 GBV_ILN_2061 GBV_ILN_2064 GBV_ILN_2065 GBV_ILN_2068 GBV_ILN_2070 GBV_ILN_2086 GBV_ILN_2088 GBV_ILN_2093 GBV_ILN_2106 GBV_ILN_2107 GBV_ILN_2108 GBV_ILN_2110 GBV_ILN_2111 GBV_ILN_2112 GBV_ILN_2113 GBV_ILN_2116 GBV_ILN_2118 GBV_ILN_2119 GBV_ILN_2122 GBV_ILN_2129 GBV_ILN_2143 GBV_ILN_2144 GBV_ILN_2147 GBV_ILN_2148 GBV_ILN_2152 GBV_ILN_2153 GBV_ILN_2188 GBV_ILN_2232 GBV_ILN_2336 GBV_ILN_2446 GBV_ILN_2470 GBV_ILN_2472 GBV_ILN_2507 GBV_ILN_2522 GBV_ILN_2548 GBV_ILN_4035 GBV_ILN_4037 GBV_ILN_4046 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4242 GBV_ILN_4246 GBV_ILN_4249 GBV_ILN_4251 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4326 GBV_ILN_4333 GBV_ILN_4334 GBV_ILN_4335 GBV_ILN_4336 GBV_ILN_4338 GBV_ILN_4393 GBV_ILN_4700 AR 2 2012 1 19 07 49-53 |
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10.1007/s13566-012-0056-5 doi (DE-627)SPR031809723 (SPR)s13566-012-0056-5-e DE-627 ger DE-627 rakwb eng 610 ASE Siddiqui, Farzan verfasserin aut Whole lung irradiation in pediatric patients using helical tomotherapy to minimize cardiac, breast, and thyroid dose 2012 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Objective The purpose of this study is to determine whether the use of helical tomotherapy can reduce dose to the heart, breast tissue, and thyroid gland in children receiving whole lung irradiation (WLI). Methods Computed tomography simulation scans from nine pediatric patients previously treated with WLI were used for this dosimetry study. Each scan was alternatively planned using helical tomotherapy to minimize dose to surrounding critical structures. The clinical target volume (CTV) included both lungs. The ribs and spine in proximity to the lungs were included in the CTV to minimize bone asymmetry resulting from partial irradiation. The planning target volume (PTV) included the CTV with a 0.8-cm margin. The following structures were contoured: right atrium, left atrium, right ventricle, left ventricle, right and left breast, thyroid gland, and the humeral heads. Median dose (Dmed), minimum dose (Dmin), and maximum dose (Dmax) for the PTV, CTV, heart chambers, thyroid gland, right and left breast as well as right and left humeral heads were also obtained. Results The median PTV receiving the prescription dose was 97 %, with PTVs ranging from 95 to 99 %. The average Dmed for each of the four chambers of the heart ranged from 37 to 55 % of the prescription dose. The average Dmed for the breasts ranged from 88 to 95 % while for the thyroid gland was 10 % of the prescription dose. Conclusion Helical tomotherapy can minimize the radiation dose delivered to nontarget organs such as the heart, breasts, and thyroid gland. Whole lung irradiation (dpeaa)DE-He213 Pediatric cancer (dpeaa)DE-He213 Wilms’ tumor (dpeaa)DE-He213 Ewing’s sarcoma (dpeaa)DE-He213 Lung metastasis (dpeaa)DE-He213 Mathews, Thomas verfasserin aut Teh, Bin S. verfasserin aut Kalapurakal, John A. verfasserin aut Butler, E. Brian verfasserin aut Chintagumpala, Murali verfasserin aut Paulino, Arnold C. verfasserin aut Enthalten in Journal of radiation oncology Berlin : Springer, 2012 2(2012), 1 vom: 19. Juli, Seite 49-53 (DE-627)718611233 (DE-600)2660511-9 1948-7908 nnns volume:2 year:2012 number:1 day:19 month:07 pages:49-53 https://dx.doi.org/10.1007/s13566-012-0056-5 lizenzpflichtig Volltext GBV_USEFLAG_A SYSFLAG_A GBV_SPRINGER SSG-OLC-PHA GBV_ILN_11 GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_32 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_70 GBV_ILN_73 GBV_ILN_74 GBV_ILN_90 GBV_ILN_95 GBV_ILN_100 GBV_ILN_101 GBV_ILN_105 GBV_ILN_110 GBV_ILN_120 GBV_ILN_138 GBV_ILN_150 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_171 GBV_ILN_187 GBV_ILN_213 GBV_ILN_224 GBV_ILN_230 GBV_ILN_250 GBV_ILN_281 GBV_ILN_285 GBV_ILN_293 GBV_ILN_370 GBV_ILN_602 GBV_ILN_636 GBV_ILN_702 GBV_ILN_2001 GBV_ILN_2003 GBV_ILN_2004 GBV_ILN_2005 GBV_ILN_2006 GBV_ILN_2007 GBV_ILN_2008 GBV_ILN_2009 GBV_ILN_2010 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2015 GBV_ILN_2020 GBV_ILN_2021 GBV_ILN_2025 GBV_ILN_2026 GBV_ILN_2027 GBV_ILN_2031 GBV_ILN_2034 GBV_ILN_2037 GBV_ILN_2038 GBV_ILN_2039 GBV_ILN_2044 GBV_ILN_2048 GBV_ILN_2049 GBV_ILN_2050 GBV_ILN_2055 GBV_ILN_2057 GBV_ILN_2059 GBV_ILN_2061 GBV_ILN_2064 GBV_ILN_2065 GBV_ILN_2068 GBV_ILN_2070 GBV_ILN_2086 GBV_ILN_2088 GBV_ILN_2093 GBV_ILN_2106 GBV_ILN_2107 GBV_ILN_2108 GBV_ILN_2110 GBV_ILN_2111 GBV_ILN_2112 GBV_ILN_2113 GBV_ILN_2116 GBV_ILN_2118 GBV_ILN_2119 GBV_ILN_2122 GBV_ILN_2129 GBV_ILN_2143 GBV_ILN_2144 GBV_ILN_2147 GBV_ILN_2148 GBV_ILN_2152 GBV_ILN_2153 GBV_ILN_2188 GBV_ILN_2232 GBV_ILN_2336 GBV_ILN_2446 GBV_ILN_2470 GBV_ILN_2472 GBV_ILN_2507 GBV_ILN_2522 GBV_ILN_2548 GBV_ILN_4035 GBV_ILN_4037 GBV_ILN_4046 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4242 GBV_ILN_4246 GBV_ILN_4249 GBV_ILN_4251 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4326 GBV_ILN_4333 GBV_ILN_4334 GBV_ILN_4335 GBV_ILN_4336 GBV_ILN_4338 GBV_ILN_4393 GBV_ILN_4700 AR 2 2012 1 19 07 49-53 |
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10.1007/s13566-012-0056-5 doi (DE-627)SPR031809723 (SPR)s13566-012-0056-5-e DE-627 ger DE-627 rakwb eng 610 ASE Siddiqui, Farzan verfasserin aut Whole lung irradiation in pediatric patients using helical tomotherapy to minimize cardiac, breast, and thyroid dose 2012 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Objective The purpose of this study is to determine whether the use of helical tomotherapy can reduce dose to the heart, breast tissue, and thyroid gland in children receiving whole lung irradiation (WLI). Methods Computed tomography simulation scans from nine pediatric patients previously treated with WLI were used for this dosimetry study. Each scan was alternatively planned using helical tomotherapy to minimize dose to surrounding critical structures. The clinical target volume (CTV) included both lungs. The ribs and spine in proximity to the lungs were included in the CTV to minimize bone asymmetry resulting from partial irradiation. The planning target volume (PTV) included the CTV with a 0.8-cm margin. The following structures were contoured: right atrium, left atrium, right ventricle, left ventricle, right and left breast, thyroid gland, and the humeral heads. Median dose (Dmed), minimum dose (Dmin), and maximum dose (Dmax) for the PTV, CTV, heart chambers, thyroid gland, right and left breast as well as right and left humeral heads were also obtained. Results The median PTV receiving the prescription dose was 97 %, with PTVs ranging from 95 to 99 %. The average Dmed for each of the four chambers of the heart ranged from 37 to 55 % of the prescription dose. The average Dmed for the breasts ranged from 88 to 95 % while for the thyroid gland was 10 % of the prescription dose. Conclusion Helical tomotherapy can minimize the radiation dose delivered to nontarget organs such as the heart, breasts, and thyroid gland. Whole lung irradiation (dpeaa)DE-He213 Pediatric cancer (dpeaa)DE-He213 Wilms’ tumor (dpeaa)DE-He213 Ewing’s sarcoma (dpeaa)DE-He213 Lung metastasis (dpeaa)DE-He213 Mathews, Thomas verfasserin aut Teh, Bin S. verfasserin aut Kalapurakal, John A. verfasserin aut Butler, E. Brian verfasserin aut Chintagumpala, Murali verfasserin aut Paulino, Arnold C. verfasserin aut Enthalten in Journal of radiation oncology Berlin : Springer, 2012 2(2012), 1 vom: 19. Juli, Seite 49-53 (DE-627)718611233 (DE-600)2660511-9 1948-7908 nnns volume:2 year:2012 number:1 day:19 month:07 pages:49-53 https://dx.doi.org/10.1007/s13566-012-0056-5 lizenzpflichtig Volltext GBV_USEFLAG_A SYSFLAG_A GBV_SPRINGER SSG-OLC-PHA GBV_ILN_11 GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_32 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_70 GBV_ILN_73 GBV_ILN_74 GBV_ILN_90 GBV_ILN_95 GBV_ILN_100 GBV_ILN_101 GBV_ILN_105 GBV_ILN_110 GBV_ILN_120 GBV_ILN_138 GBV_ILN_150 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_171 GBV_ILN_187 GBV_ILN_213 GBV_ILN_224 GBV_ILN_230 GBV_ILN_250 GBV_ILN_281 GBV_ILN_285 GBV_ILN_293 GBV_ILN_370 GBV_ILN_602 GBV_ILN_636 GBV_ILN_702 GBV_ILN_2001 GBV_ILN_2003 GBV_ILN_2004 GBV_ILN_2005 GBV_ILN_2006 GBV_ILN_2007 GBV_ILN_2008 GBV_ILN_2009 GBV_ILN_2010 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2015 GBV_ILN_2020 GBV_ILN_2021 GBV_ILN_2025 GBV_ILN_2026 GBV_ILN_2027 GBV_ILN_2031 GBV_ILN_2034 GBV_ILN_2037 GBV_ILN_2038 GBV_ILN_2039 GBV_ILN_2044 GBV_ILN_2048 GBV_ILN_2049 GBV_ILN_2050 GBV_ILN_2055 GBV_ILN_2057 GBV_ILN_2059 GBV_ILN_2061 GBV_ILN_2064 GBV_ILN_2065 GBV_ILN_2068 GBV_ILN_2070 GBV_ILN_2086 GBV_ILN_2088 GBV_ILN_2093 GBV_ILN_2106 GBV_ILN_2107 GBV_ILN_2108 GBV_ILN_2110 GBV_ILN_2111 GBV_ILN_2112 GBV_ILN_2113 GBV_ILN_2116 GBV_ILN_2118 GBV_ILN_2119 GBV_ILN_2122 GBV_ILN_2129 GBV_ILN_2143 GBV_ILN_2144 GBV_ILN_2147 GBV_ILN_2148 GBV_ILN_2152 GBV_ILN_2153 GBV_ILN_2188 GBV_ILN_2232 GBV_ILN_2336 GBV_ILN_2446 GBV_ILN_2470 GBV_ILN_2472 GBV_ILN_2507 GBV_ILN_2522 GBV_ILN_2548 GBV_ILN_4035 GBV_ILN_4037 GBV_ILN_4046 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4242 GBV_ILN_4246 GBV_ILN_4249 GBV_ILN_4251 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4326 GBV_ILN_4333 GBV_ILN_4334 GBV_ILN_4335 GBV_ILN_4336 GBV_ILN_4338 GBV_ILN_4393 GBV_ILN_4700 AR 2 2012 1 19 07 49-53 |
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Enthalten in Journal of radiation oncology 2(2012), 1 vom: 19. Juli, Seite 49-53 volume:2 year:2012 number:1 day:19 month:07 pages:49-53 |
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Enthalten in Journal of radiation oncology 2(2012), 1 vom: 19. Juli, Seite 49-53 volume:2 year:2012 number:1 day:19 month:07 pages:49-53 |
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Whole lung irradiation Pediatric cancer Wilms’ tumor Ewing’s sarcoma Lung metastasis |
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Siddiqui, Farzan @@aut@@ Mathews, Thomas @@aut@@ Teh, Bin S. @@aut@@ Kalapurakal, John A. @@aut@@ Butler, E. Brian @@aut@@ Chintagumpala, Murali @@aut@@ Paulino, Arnold C. @@aut@@ |
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2012-07-19T00:00:00Z |
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<?xml version="1.0" encoding="UTF-8"?><collection xmlns="http://www.loc.gov/MARC21/slim"><record><leader>01000caa a22002652 4500</leader><controlfield tag="001">SPR031809723</controlfield><controlfield tag="003">DE-627</controlfield><controlfield tag="005">20230519141835.0</controlfield><controlfield tag="007">cr uuu---uuuuu</controlfield><controlfield tag="008">201007s2012 xx |||||o 00| ||eng c</controlfield><datafield tag="024" ind1="7" ind2=" "><subfield code="a">10.1007/s13566-012-0056-5</subfield><subfield code="2">doi</subfield></datafield><datafield tag="035" ind1=" " ind2=" "><subfield code="a">(DE-627)SPR031809723</subfield></datafield><datafield tag="035" ind1=" " ind2=" "><subfield code="a">(SPR)s13566-012-0056-5-e</subfield></datafield><datafield tag="040" ind1=" " ind2=" "><subfield code="a">DE-627</subfield><subfield code="b">ger</subfield><subfield code="c">DE-627</subfield><subfield code="e">rakwb</subfield></datafield><datafield tag="041" ind1=" " ind2=" "><subfield code="a">eng</subfield></datafield><datafield tag="082" ind1="0" ind2="4"><subfield code="a">610</subfield><subfield code="q">ASE</subfield></datafield><datafield tag="100" ind1="1" ind2=" "><subfield code="a">Siddiqui, Farzan</subfield><subfield code="e">verfasserin</subfield><subfield code="4">aut</subfield></datafield><datafield tag="245" ind1="1" ind2="0"><subfield code="a">Whole lung irradiation in pediatric patients using helical tomotherapy to minimize cardiac, breast, and thyroid dose</subfield></datafield><datafield tag="264" ind1=" " ind2="1"><subfield code="c">2012</subfield></datafield><datafield tag="336" ind1=" " ind2=" "><subfield code="a">Text</subfield><subfield code="b">txt</subfield><subfield code="2">rdacontent</subfield></datafield><datafield tag="337" ind1=" " ind2=" "><subfield code="a">Computermedien</subfield><subfield code="b">c</subfield><subfield code="2">rdamedia</subfield></datafield><datafield tag="338" ind1=" " ind2=" "><subfield code="a">Online-Ressource</subfield><subfield code="b">cr</subfield><subfield code="2">rdacarrier</subfield></datafield><datafield tag="520" ind1=" " ind2=" "><subfield code="a">Objective The purpose of this study is to determine whether the use of helical tomotherapy can reduce dose to the heart, breast tissue, and thyroid gland in children receiving whole lung irradiation (WLI). Methods Computed tomography simulation scans from nine pediatric patients previously treated with WLI were used for this dosimetry study. Each scan was alternatively planned using helical tomotherapy to minimize dose to surrounding critical structures. The clinical target volume (CTV) included both lungs. The ribs and spine in proximity to the lungs were included in the CTV to minimize bone asymmetry resulting from partial irradiation. The planning target volume (PTV) included the CTV with a 0.8-cm margin. The following structures were contoured: right atrium, left atrium, right ventricle, left ventricle, right and left breast, thyroid gland, and the humeral heads. Median dose (Dmed), minimum dose (Dmin), and maximum dose (Dmax) for the PTV, CTV, heart chambers, thyroid gland, right and left breast as well as right and left humeral heads were also obtained. Results The median PTV receiving the prescription dose was 97 %, with PTVs ranging from 95 to 99 %. The average Dmed for each of the four chambers of the heart ranged from 37 to 55 % of the prescription dose. The average Dmed for the breasts ranged from 88 to 95 % while for the thyroid gland was 10 % of the prescription dose. 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Siddiqui, Farzan |
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Siddiqui, Farzan ddc 610 misc Whole lung irradiation misc Pediatric cancer misc Wilms’ tumor misc Ewing’s sarcoma misc Lung metastasis Whole lung irradiation in pediatric patients using helical tomotherapy to minimize cardiac, breast, and thyroid dose |
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610 ASE Whole lung irradiation in pediatric patients using helical tomotherapy to minimize cardiac, breast, and thyroid dose Whole lung irradiation (dpeaa)DE-He213 Pediatric cancer (dpeaa)DE-He213 Wilms’ tumor (dpeaa)DE-He213 Ewing’s sarcoma (dpeaa)DE-He213 Lung metastasis (dpeaa)DE-He213 |
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Siddiqui, Farzan Mathews, Thomas Teh, Bin S. Kalapurakal, John A. Butler, E. Brian Chintagumpala, Murali Paulino, Arnold C. |
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whole lung irradiation in pediatric patients using helical tomotherapy to minimize cardiac, breast, and thyroid dose |
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Whole lung irradiation in pediatric patients using helical tomotherapy to minimize cardiac, breast, and thyroid dose |
| abstract |
Objective The purpose of this study is to determine whether the use of helical tomotherapy can reduce dose to the heart, breast tissue, and thyroid gland in children receiving whole lung irradiation (WLI). Methods Computed tomography simulation scans from nine pediatric patients previously treated with WLI were used for this dosimetry study. Each scan was alternatively planned using helical tomotherapy to minimize dose to surrounding critical structures. The clinical target volume (CTV) included both lungs. The ribs and spine in proximity to the lungs were included in the CTV to minimize bone asymmetry resulting from partial irradiation. The planning target volume (PTV) included the CTV with a 0.8-cm margin. The following structures were contoured: right atrium, left atrium, right ventricle, left ventricle, right and left breast, thyroid gland, and the humeral heads. Median dose (Dmed), minimum dose (Dmin), and maximum dose (Dmax) for the PTV, CTV, heart chambers, thyroid gland, right and left breast as well as right and left humeral heads were also obtained. Results The median PTV receiving the prescription dose was 97 %, with PTVs ranging from 95 to 99 %. The average Dmed for each of the four chambers of the heart ranged from 37 to 55 % of the prescription dose. The average Dmed for the breasts ranged from 88 to 95 % while for the thyroid gland was 10 % of the prescription dose. Conclusion Helical tomotherapy can minimize the radiation dose delivered to nontarget organs such as the heart, breasts, and thyroid gland. |
| abstractGer |
Objective The purpose of this study is to determine whether the use of helical tomotherapy can reduce dose to the heart, breast tissue, and thyroid gland in children receiving whole lung irradiation (WLI). Methods Computed tomography simulation scans from nine pediatric patients previously treated with WLI were used for this dosimetry study. Each scan was alternatively planned using helical tomotherapy to minimize dose to surrounding critical structures. The clinical target volume (CTV) included both lungs. The ribs and spine in proximity to the lungs were included in the CTV to minimize bone asymmetry resulting from partial irradiation. The planning target volume (PTV) included the CTV with a 0.8-cm margin. The following structures were contoured: right atrium, left atrium, right ventricle, left ventricle, right and left breast, thyroid gland, and the humeral heads. Median dose (Dmed), minimum dose (Dmin), and maximum dose (Dmax) for the PTV, CTV, heart chambers, thyroid gland, right and left breast as well as right and left humeral heads were also obtained. Results The median PTV receiving the prescription dose was 97 %, with PTVs ranging from 95 to 99 %. The average Dmed for each of the four chambers of the heart ranged from 37 to 55 % of the prescription dose. The average Dmed for the breasts ranged from 88 to 95 % while for the thyroid gland was 10 % of the prescription dose. Conclusion Helical tomotherapy can minimize the radiation dose delivered to nontarget organs such as the heart, breasts, and thyroid gland. |
| abstract_unstemmed |
Objective The purpose of this study is to determine whether the use of helical tomotherapy can reduce dose to the heart, breast tissue, and thyroid gland in children receiving whole lung irradiation (WLI). Methods Computed tomography simulation scans from nine pediatric patients previously treated with WLI were used for this dosimetry study. Each scan was alternatively planned using helical tomotherapy to minimize dose to surrounding critical structures. The clinical target volume (CTV) included both lungs. The ribs and spine in proximity to the lungs were included in the CTV to minimize bone asymmetry resulting from partial irradiation. The planning target volume (PTV) included the CTV with a 0.8-cm margin. The following structures were contoured: right atrium, left atrium, right ventricle, left ventricle, right and left breast, thyroid gland, and the humeral heads. Median dose (Dmed), minimum dose (Dmin), and maximum dose (Dmax) for the PTV, CTV, heart chambers, thyroid gland, right and left breast as well as right and left humeral heads were also obtained. Results The median PTV receiving the prescription dose was 97 %, with PTVs ranging from 95 to 99 %. The average Dmed for each of the four chambers of the heart ranged from 37 to 55 % of the prescription dose. The average Dmed for the breasts ranged from 88 to 95 % while for the thyroid gland was 10 % of the prescription dose. Conclusion Helical tomotherapy can minimize the radiation dose delivered to nontarget organs such as the heart, breasts, and thyroid gland. |
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Whole lung irradiation in pediatric patients using helical tomotherapy to minimize cardiac, breast, and thyroid dose |
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https://dx.doi.org/10.1007/s13566-012-0056-5 |
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| author2 |
Mathews, Thomas Teh, Bin S. Kalapurakal, John A. Butler, E. Brian Chintagumpala, Murali Paulino, Arnold C. |
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Mathews, Thomas Teh, Bin S. Kalapurakal, John A. Butler, E. Brian Chintagumpala, Murali Paulino, Arnold C. |
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10.1007/s13566-012-0056-5 |
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2024-07-04T01:20:15.737Z |
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| score |
7.402158 |