Radiation emergencies: radiation-related brain and lung injury

Background The advent of modern radiation techniques, such as intensity modulated and stereotactic ablative radiation therapy, has permitted increasingly accurate delivery of radiation, with ability to shape distribution of dose specifically to the tumor. These techniques limit dose to surrounding n...
Ausführliche Beschreibung

Gespeichert in:

Autor*in:	Ning, Matthew S. [verfasserIn] Kaminski, Joseph M. [verfasserIn] Pucar, Darko [verfasserIn] Shinohara, Eric T. [verfasserIn]

Format:	E-Artikel
Sprache:	Englisch

Erschienen:	2015

Schlagwörter:	Radiation toxicity Cranial irradiation Pseudoprogression Radiation necrosis Radiation pneumonitis Radiation fibrosis

Übergeordnetes Werk:	Enthalten in: Journal of radiation oncology - Berlin : Springer, 2012, 5(2015), 1 vom: 15. Dez., Seite 9-17
Übergeordnetes Werk:	volume:5 ; year:2015 ; number:1 ; day:15 ; month:12 ; pages:9-17

Links:	Volltext

DOI / URN:	10.1007/s13566-015-0241-4

Katalog-ID:	SPR031811698

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520			\|a Background The advent of modern radiation techniques, such as intensity modulated and stereotactic ablative radiation therapy, has permitted increasingly accurate delivery of radiation, with ability to shape distribution of dose specifically to the tumor. These techniques limit dose to surrounding normal tissue in an effort to reduce toxicity; however, despite such improvements, potentially serious side effects related to treatment may occur, requiring urgent management. Objective Radiation-related brain or lung injury in previously irradiated patients may present in the acute or late post-treatment setting. Patients initially present with non-specific symptoms associated with the organ in question, representing a diagnostic challenge in the emergency room. Here, we review potential complications that may occur following radiation therapy to two commonly treated sites: brain and thorax. Conclusions We provide a guideline of the presentation, diagnosis, and management of these complications to function as a useful resource for healthcare providers. Furthermore, we review thedosimetric and volumetric parameters associated with such adverse events.
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650		4	\|a Radiation fibrosis \|7 (dpeaa)DE-He213
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700	1		\|a Shinohara, Eric T. \|e verfasserin \|4 aut
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allfields	10.1007/s13566-015-0241-4 doi (DE-627)SPR031811698 (SPR)s13566-015-0241-4-e DE-627 ger DE-627 rakwb eng 610 ASE Ning, Matthew S. verfasserin aut Radiation emergencies: radiation-related brain and lung injury 2015 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Background The advent of modern radiation techniques, such as intensity modulated and stereotactic ablative radiation therapy, has permitted increasingly accurate delivery of radiation, with ability to shape distribution of dose specifically to the tumor. These techniques limit dose to surrounding normal tissue in an effort to reduce toxicity; however, despite such improvements, potentially serious side effects related to treatment may occur, requiring urgent management. Objective Radiation-related brain or lung injury in previously irradiated patients may present in the acute or late post-treatment setting. Patients initially present with non-specific symptoms associated with the organ in question, representing a diagnostic challenge in the emergency room. Here, we review potential complications that may occur following radiation therapy to two commonly treated sites: brain and thorax. Conclusions We provide a guideline of the presentation, diagnosis, and management of these complications to function as a useful resource for healthcare providers. Furthermore, we review thedosimetric and volumetric parameters associated with such adverse events. Radiation toxicity (dpeaa)DE-He213 Cranial irradiation (dpeaa)DE-He213 Pseudoprogression (dpeaa)DE-He213 Radiation necrosis (dpeaa)DE-He213 Radiation pneumonitis (dpeaa)DE-He213 Radiation fibrosis (dpeaa)DE-He213 Kaminski, Joseph M. verfasserin aut Pucar, Darko verfasserin aut Shinohara, Eric T. verfasserin aut Enthalten in Journal of radiation oncology Berlin : Springer, 2012 5(2015), 1 vom: 15. Dez., Seite 9-17 (DE-627)718611233 (DE-600)2660511-9 1948-7908 nnns volume:5 year:2015 number:1 day:15 month:12 pages:9-17 https://dx.doi.org/10.1007/s13566-015-0241-4 lizenzpflichtig Volltext GBV_USEFLAG_A SYSFLAG_A GBV_SPRINGER SSG-OLC-PHA GBV_ILN_11 GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_32 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_70 GBV_ILN_73 GBV_ILN_74 GBV_ILN_90 GBV_ILN_95 GBV_ILN_100 GBV_ILN_101 GBV_ILN_105 GBV_ILN_110 GBV_ILN_120 GBV_ILN_138 GBV_ILN_150 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_171 GBV_ILN_187 GBV_ILN_213 GBV_ILN_224 GBV_ILN_230 GBV_ILN_250 GBV_ILN_281 GBV_ILN_285 GBV_ILN_293 GBV_ILN_370 GBV_ILN_602 GBV_ILN_636 GBV_ILN_702 GBV_ILN_2001 GBV_ILN_2003 GBV_ILN_2004 GBV_ILN_2005 GBV_ILN_2006 GBV_ILN_2007 GBV_ILN_2008 GBV_ILN_2009 GBV_ILN_2010 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2015 GBV_ILN_2020 GBV_ILN_2021 GBV_ILN_2025 GBV_ILN_2026 GBV_ILN_2027 GBV_ILN_2031 GBV_ILN_2034 GBV_ILN_2037 GBV_ILN_2038 GBV_ILN_2039 GBV_ILN_2044 GBV_ILN_2048 GBV_ILN_2049 GBV_ILN_2050 GBV_ILN_2055 GBV_ILN_2057 GBV_ILN_2059 GBV_ILN_2061 GBV_ILN_2064 GBV_ILN_2065 GBV_ILN_2068 GBV_ILN_2070 GBV_ILN_2086 GBV_ILN_2088 GBV_ILN_2093 GBV_ILN_2106 GBV_ILN_2107 GBV_ILN_2108 GBV_ILN_2110 GBV_ILN_2111 GBV_ILN_2112 GBV_ILN_2113 GBV_ILN_2116 GBV_ILN_2118 GBV_ILN_2119 GBV_ILN_2122 GBV_ILN_2129 GBV_ILN_2143 GBV_ILN_2144 GBV_ILN_2147 GBV_ILN_2148 GBV_ILN_2152 GBV_ILN_2153 GBV_ILN_2188 GBV_ILN_2232 GBV_ILN_2336 GBV_ILN_2446 GBV_ILN_2470 GBV_ILN_2472 GBV_ILN_2507 GBV_ILN_2522 GBV_ILN_2548 GBV_ILN_4035 GBV_ILN_4037 GBV_ILN_4046 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4242 GBV_ILN_4246 GBV_ILN_4249 GBV_ILN_4251 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4326 GBV_ILN_4333 GBV_ILN_4334 GBV_ILN_4335 GBV_ILN_4336 GBV_ILN_4338 GBV_ILN_4393 GBV_ILN_4700 AR 5 2015 1 15 12 9-17
spelling	10.1007/s13566-015-0241-4 doi (DE-627)SPR031811698 (SPR)s13566-015-0241-4-e DE-627 ger DE-627 rakwb eng 610 ASE Ning, Matthew S. verfasserin aut Radiation emergencies: radiation-related brain and lung injury 2015 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Background The advent of modern radiation techniques, such as intensity modulated and stereotactic ablative radiation therapy, has permitted increasingly accurate delivery of radiation, with ability to shape distribution of dose specifically to the tumor. These techniques limit dose to surrounding normal tissue in an effort to reduce toxicity; however, despite such improvements, potentially serious side effects related to treatment may occur, requiring urgent management. Objective Radiation-related brain or lung injury in previously irradiated patients may present in the acute or late post-treatment setting. Patients initially present with non-specific symptoms associated with the organ in question, representing a diagnostic challenge in the emergency room. Here, we review potential complications that may occur following radiation therapy to two commonly treated sites: brain and thorax. Conclusions We provide a guideline of the presentation, diagnosis, and management of these complications to function as a useful resource for healthcare providers. Furthermore, we review thedosimetric and volumetric parameters associated with such adverse events. Radiation toxicity (dpeaa)DE-He213 Cranial irradiation (dpeaa)DE-He213 Pseudoprogression (dpeaa)DE-He213 Radiation necrosis (dpeaa)DE-He213 Radiation pneumonitis (dpeaa)DE-He213 Radiation fibrosis (dpeaa)DE-He213 Kaminski, Joseph M. verfasserin aut Pucar, Darko verfasserin aut Shinohara, Eric T. verfasserin aut Enthalten in Journal of radiation oncology Berlin : Springer, 2012 5(2015), 1 vom: 15. Dez., Seite 9-17 (DE-627)718611233 (DE-600)2660511-9 1948-7908 nnns volume:5 year:2015 number:1 day:15 month:12 pages:9-17 https://dx.doi.org/10.1007/s13566-015-0241-4 lizenzpflichtig Volltext GBV_USEFLAG_A SYSFLAG_A GBV_SPRINGER SSG-OLC-PHA GBV_ILN_11 GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_32 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_70 GBV_ILN_73 GBV_ILN_74 GBV_ILN_90 GBV_ILN_95 GBV_ILN_100 GBV_ILN_101 GBV_ILN_105 GBV_ILN_110 GBV_ILN_120 GBV_ILN_138 GBV_ILN_150 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_171 GBV_ILN_187 GBV_ILN_213 GBV_ILN_224 GBV_ILN_230 GBV_ILN_250 GBV_ILN_281 GBV_ILN_285 GBV_ILN_293 GBV_ILN_370 GBV_ILN_602 GBV_ILN_636 GBV_ILN_702 GBV_ILN_2001 GBV_ILN_2003 GBV_ILN_2004 GBV_ILN_2005 GBV_ILN_2006 GBV_ILN_2007 GBV_ILN_2008 GBV_ILN_2009 GBV_ILN_2010 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2015 GBV_ILN_2020 GBV_ILN_2021 GBV_ILN_2025 GBV_ILN_2026 GBV_ILN_2027 GBV_ILN_2031 GBV_ILN_2034 GBV_ILN_2037 GBV_ILN_2038 GBV_ILN_2039 GBV_ILN_2044 GBV_ILN_2048 GBV_ILN_2049 GBV_ILN_2050 GBV_ILN_2055 GBV_ILN_2057 GBV_ILN_2059 GBV_ILN_2061 GBV_ILN_2064 GBV_ILN_2065 GBV_ILN_2068 GBV_ILN_2070 GBV_ILN_2086 GBV_ILN_2088 GBV_ILN_2093 GBV_ILN_2106 GBV_ILN_2107 GBV_ILN_2108 GBV_ILN_2110 GBV_ILN_2111 GBV_ILN_2112 GBV_ILN_2113 GBV_ILN_2116 GBV_ILN_2118 GBV_ILN_2119 GBV_ILN_2122 GBV_ILN_2129 GBV_ILN_2143 GBV_ILN_2144 GBV_ILN_2147 GBV_ILN_2148 GBV_ILN_2152 GBV_ILN_2153 GBV_ILN_2188 GBV_ILN_2232 GBV_ILN_2336 GBV_ILN_2446 GBV_ILN_2470 GBV_ILN_2472 GBV_ILN_2507 GBV_ILN_2522 GBV_ILN_2548 GBV_ILN_4035 GBV_ILN_4037 GBV_ILN_4046 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4242 GBV_ILN_4246 GBV_ILN_4249 GBV_ILN_4251 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4326 GBV_ILN_4333 GBV_ILN_4334 GBV_ILN_4335 GBV_ILN_4336 GBV_ILN_4338 GBV_ILN_4393 GBV_ILN_4700 AR 5 2015 1 15 12 9-17
allfields_unstemmed	10.1007/s13566-015-0241-4 doi (DE-627)SPR031811698 (SPR)s13566-015-0241-4-e DE-627 ger DE-627 rakwb eng 610 ASE Ning, Matthew S. verfasserin aut Radiation emergencies: radiation-related brain and lung injury 2015 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Background The advent of modern radiation techniques, such as intensity modulated and stereotactic ablative radiation therapy, has permitted increasingly accurate delivery of radiation, with ability to shape distribution of dose specifically to the tumor. These techniques limit dose to surrounding normal tissue in an effort to reduce toxicity; however, despite such improvements, potentially serious side effects related to treatment may occur, requiring urgent management. Objective Radiation-related brain or lung injury in previously irradiated patients may present in the acute or late post-treatment setting. Patients initially present with non-specific symptoms associated with the organ in question, representing a diagnostic challenge in the emergency room. Here, we review potential complications that may occur following radiation therapy to two commonly treated sites: brain and thorax. Conclusions We provide a guideline of the presentation, diagnosis, and management of these complications to function as a useful resource for healthcare providers. Furthermore, we review thedosimetric and volumetric parameters associated with such adverse events. Radiation toxicity (dpeaa)DE-He213 Cranial irradiation (dpeaa)DE-He213 Pseudoprogression (dpeaa)DE-He213 Radiation necrosis (dpeaa)DE-He213 Radiation pneumonitis (dpeaa)DE-He213 Radiation fibrosis (dpeaa)DE-He213 Kaminski, Joseph M. verfasserin aut Pucar, Darko verfasserin aut Shinohara, Eric T. verfasserin aut Enthalten in Journal of radiation oncology Berlin : Springer, 2012 5(2015), 1 vom: 15. Dez., Seite 9-17 (DE-627)718611233 (DE-600)2660511-9 1948-7908 nnns volume:5 year:2015 number:1 day:15 month:12 pages:9-17 https://dx.doi.org/10.1007/s13566-015-0241-4 lizenzpflichtig Volltext GBV_USEFLAG_A SYSFLAG_A GBV_SPRINGER SSG-OLC-PHA GBV_ILN_11 GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_32 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_70 GBV_ILN_73 GBV_ILN_74 GBV_ILN_90 GBV_ILN_95 GBV_ILN_100 GBV_ILN_101 GBV_ILN_105 GBV_ILN_110 GBV_ILN_120 GBV_ILN_138 GBV_ILN_150 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_171 GBV_ILN_187 GBV_ILN_213 GBV_ILN_224 GBV_ILN_230 GBV_ILN_250 GBV_ILN_281 GBV_ILN_285 GBV_ILN_293 GBV_ILN_370 GBV_ILN_602 GBV_ILN_636 GBV_ILN_702 GBV_ILN_2001 GBV_ILN_2003 GBV_ILN_2004 GBV_ILN_2005 GBV_ILN_2006 GBV_ILN_2007 GBV_ILN_2008 GBV_ILN_2009 GBV_ILN_2010 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2015 GBV_ILN_2020 GBV_ILN_2021 GBV_ILN_2025 GBV_ILN_2026 GBV_ILN_2027 GBV_ILN_2031 GBV_ILN_2034 GBV_ILN_2037 GBV_ILN_2038 GBV_ILN_2039 GBV_ILN_2044 GBV_ILN_2048 GBV_ILN_2049 GBV_ILN_2050 GBV_ILN_2055 GBV_ILN_2057 GBV_ILN_2059 GBV_ILN_2061 GBV_ILN_2064 GBV_ILN_2065 GBV_ILN_2068 GBV_ILN_2070 GBV_ILN_2086 GBV_ILN_2088 GBV_ILN_2093 GBV_ILN_2106 GBV_ILN_2107 GBV_ILN_2108 GBV_ILN_2110 GBV_ILN_2111 GBV_ILN_2112 GBV_ILN_2113 GBV_ILN_2116 GBV_ILN_2118 GBV_ILN_2119 GBV_ILN_2122 GBV_ILN_2129 GBV_ILN_2143 GBV_ILN_2144 GBV_ILN_2147 GBV_ILN_2148 GBV_ILN_2152 GBV_ILN_2153 GBV_ILN_2188 GBV_ILN_2232 GBV_ILN_2336 GBV_ILN_2446 GBV_ILN_2470 GBV_ILN_2472 GBV_ILN_2507 GBV_ILN_2522 GBV_ILN_2548 GBV_ILN_4035 GBV_ILN_4037 GBV_ILN_4046 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4242 GBV_ILN_4246 GBV_ILN_4249 GBV_ILN_4251 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4326 GBV_ILN_4333 GBV_ILN_4334 GBV_ILN_4335 GBV_ILN_4336 GBV_ILN_4338 GBV_ILN_4393 GBV_ILN_4700 AR 5 2015 1 15 12 9-17
allfieldsGer	10.1007/s13566-015-0241-4 doi (DE-627)SPR031811698 (SPR)s13566-015-0241-4-e DE-627 ger DE-627 rakwb eng 610 ASE Ning, Matthew S. verfasserin aut Radiation emergencies: radiation-related brain and lung injury 2015 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Background The advent of modern radiation techniques, such as intensity modulated and stereotactic ablative radiation therapy, has permitted increasingly accurate delivery of radiation, with ability to shape distribution of dose specifically to the tumor. These techniques limit dose to surrounding normal tissue in an effort to reduce toxicity; however, despite such improvements, potentially serious side effects related to treatment may occur, requiring urgent management. Objective Radiation-related brain or lung injury in previously irradiated patients may present in the acute or late post-treatment setting. Patients initially present with non-specific symptoms associated with the organ in question, representing a diagnostic challenge in the emergency room. Here, we review potential complications that may occur following radiation therapy to two commonly treated sites: brain and thorax. Conclusions We provide a guideline of the presentation, diagnosis, and management of these complications to function as a useful resource for healthcare providers. Furthermore, we review thedosimetric and volumetric parameters associated with such adverse events. Radiation toxicity (dpeaa)DE-He213 Cranial irradiation (dpeaa)DE-He213 Pseudoprogression (dpeaa)DE-He213 Radiation necrosis (dpeaa)DE-He213 Radiation pneumonitis (dpeaa)DE-He213 Radiation fibrosis (dpeaa)DE-He213 Kaminski, Joseph M. verfasserin aut Pucar, Darko verfasserin aut Shinohara, Eric T. verfasserin aut Enthalten in Journal of radiation oncology Berlin : Springer, 2012 5(2015), 1 vom: 15. Dez., Seite 9-17 (DE-627)718611233 (DE-600)2660511-9 1948-7908 nnns volume:5 year:2015 number:1 day:15 month:12 pages:9-17 https://dx.doi.org/10.1007/s13566-015-0241-4 lizenzpflichtig Volltext GBV_USEFLAG_A SYSFLAG_A GBV_SPRINGER SSG-OLC-PHA GBV_ILN_11 GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_32 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_70 GBV_ILN_73 GBV_ILN_74 GBV_ILN_90 GBV_ILN_95 GBV_ILN_100 GBV_ILN_101 GBV_ILN_105 GBV_ILN_110 GBV_ILN_120 GBV_ILN_138 GBV_ILN_150 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_171 GBV_ILN_187 GBV_ILN_213 GBV_ILN_224 GBV_ILN_230 GBV_ILN_250 GBV_ILN_281 GBV_ILN_285 GBV_ILN_293 GBV_ILN_370 GBV_ILN_602 GBV_ILN_636 GBV_ILN_702 GBV_ILN_2001 GBV_ILN_2003 GBV_ILN_2004 GBV_ILN_2005 GBV_ILN_2006 GBV_ILN_2007 GBV_ILN_2008 GBV_ILN_2009 GBV_ILN_2010 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2015 GBV_ILN_2020 GBV_ILN_2021 GBV_ILN_2025 GBV_ILN_2026 GBV_ILN_2027 GBV_ILN_2031 GBV_ILN_2034 GBV_ILN_2037 GBV_ILN_2038 GBV_ILN_2039 GBV_ILN_2044 GBV_ILN_2048 GBV_ILN_2049 GBV_ILN_2050 GBV_ILN_2055 GBV_ILN_2057 GBV_ILN_2059 GBV_ILN_2061 GBV_ILN_2064 GBV_ILN_2065 GBV_ILN_2068 GBV_ILN_2070 GBV_ILN_2086 GBV_ILN_2088 GBV_ILN_2093 GBV_ILN_2106 GBV_ILN_2107 GBV_ILN_2108 GBV_ILN_2110 GBV_ILN_2111 GBV_ILN_2112 GBV_ILN_2113 GBV_ILN_2116 GBV_ILN_2118 GBV_ILN_2119 GBV_ILN_2122 GBV_ILN_2129 GBV_ILN_2143 GBV_ILN_2144 GBV_ILN_2147 GBV_ILN_2148 GBV_ILN_2152 GBV_ILN_2153 GBV_ILN_2188 GBV_ILN_2232 GBV_ILN_2336 GBV_ILN_2446 GBV_ILN_2470 GBV_ILN_2472 GBV_ILN_2507 GBV_ILN_2522 GBV_ILN_2548 GBV_ILN_4035 GBV_ILN_4037 GBV_ILN_4046 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4242 GBV_ILN_4246 GBV_ILN_4249 GBV_ILN_4251 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4326 GBV_ILN_4333 GBV_ILN_4334 GBV_ILN_4335 GBV_ILN_4336 GBV_ILN_4338 GBV_ILN_4393 GBV_ILN_4700 AR 5 2015 1 15 12 9-17
allfieldsSound	10.1007/s13566-015-0241-4 doi (DE-627)SPR031811698 (SPR)s13566-015-0241-4-e DE-627 ger DE-627 rakwb eng 610 ASE Ning, Matthew S. verfasserin aut Radiation emergencies: radiation-related brain and lung injury 2015 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Background The advent of modern radiation techniques, such as intensity modulated and stereotactic ablative radiation therapy, has permitted increasingly accurate delivery of radiation, with ability to shape distribution of dose specifically to the tumor. These techniques limit dose to surrounding normal tissue in an effort to reduce toxicity; however, despite such improvements, potentially serious side effects related to treatment may occur, requiring urgent management. Objective Radiation-related brain or lung injury in previously irradiated patients may present in the acute or late post-treatment setting. Patients initially present with non-specific symptoms associated with the organ in question, representing a diagnostic challenge in the emergency room. Here, we review potential complications that may occur following radiation therapy to two commonly treated sites: brain and thorax. Conclusions We provide a guideline of the presentation, diagnosis, and management of these complications to function as a useful resource for healthcare providers. Furthermore, we review thedosimetric and volumetric parameters associated with such adverse events. Radiation toxicity (dpeaa)DE-He213 Cranial irradiation (dpeaa)DE-He213 Pseudoprogression (dpeaa)DE-He213 Radiation necrosis (dpeaa)DE-He213 Radiation pneumonitis (dpeaa)DE-He213 Radiation fibrosis (dpeaa)DE-He213 Kaminski, Joseph M. verfasserin aut Pucar, Darko verfasserin aut Shinohara, Eric T. verfasserin aut Enthalten in Journal of radiation oncology Berlin : Springer, 2012 5(2015), 1 vom: 15. Dez., Seite 9-17 (DE-627)718611233 (DE-600)2660511-9 1948-7908 nnns volume:5 year:2015 number:1 day:15 month:12 pages:9-17 https://dx.doi.org/10.1007/s13566-015-0241-4 lizenzpflichtig Volltext GBV_USEFLAG_A SYSFLAG_A GBV_SPRINGER SSG-OLC-PHA GBV_ILN_11 GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_32 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_70 GBV_ILN_73 GBV_ILN_74 GBV_ILN_90 GBV_ILN_95 GBV_ILN_100 GBV_ILN_101 GBV_ILN_105 GBV_ILN_110 GBV_ILN_120 GBV_ILN_138 GBV_ILN_150 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_171 GBV_ILN_187 GBV_ILN_213 GBV_ILN_224 GBV_ILN_230 GBV_ILN_250 GBV_ILN_281 GBV_ILN_285 GBV_ILN_293 GBV_ILN_370 GBV_ILN_602 GBV_ILN_636 GBV_ILN_702 GBV_ILN_2001 GBV_ILN_2003 GBV_ILN_2004 GBV_ILN_2005 GBV_ILN_2006 GBV_ILN_2007 GBV_ILN_2008 GBV_ILN_2009 GBV_ILN_2010 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2015 GBV_ILN_2020 GBV_ILN_2021 GBV_ILN_2025 GBV_ILN_2026 GBV_ILN_2027 GBV_ILN_2031 GBV_ILN_2034 GBV_ILN_2037 GBV_ILN_2038 GBV_ILN_2039 GBV_ILN_2044 GBV_ILN_2048 GBV_ILN_2049 GBV_ILN_2050 GBV_ILN_2055 GBV_ILN_2057 GBV_ILN_2059 GBV_ILN_2061 GBV_ILN_2064 GBV_ILN_2065 GBV_ILN_2068 GBV_ILN_2070 GBV_ILN_2086 GBV_ILN_2088 GBV_ILN_2093 GBV_ILN_2106 GBV_ILN_2107 GBV_ILN_2108 GBV_ILN_2110 GBV_ILN_2111 GBV_ILN_2112 GBV_ILN_2113 GBV_ILN_2116 GBV_ILN_2118 GBV_ILN_2119 GBV_ILN_2122 GBV_ILN_2129 GBV_ILN_2143 GBV_ILN_2144 GBV_ILN_2147 GBV_ILN_2148 GBV_ILN_2152 GBV_ILN_2153 GBV_ILN_2188 GBV_ILN_2232 GBV_ILN_2336 GBV_ILN_2446 GBV_ILN_2470 GBV_ILN_2472 GBV_ILN_2507 GBV_ILN_2522 GBV_ILN_2548 GBV_ILN_4035 GBV_ILN_4037 GBV_ILN_4046 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4242 GBV_ILN_4246 GBV_ILN_4249 GBV_ILN_4251 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4326 GBV_ILN_4333 GBV_ILN_4334 GBV_ILN_4335 GBV_ILN_4336 GBV_ILN_4338 GBV_ILN_4393 GBV_ILN_4700 AR 5 2015 1 15 12 9-17
language	English
source	Enthalten in Journal of radiation oncology 5(2015), 1 vom: 15. Dez., Seite 9-17 volume:5 year:2015 number:1 day:15 month:12 pages:9-17
sourceStr	Enthalten in Journal of radiation oncology 5(2015), 1 vom: 15. Dez., Seite 9-17 volume:5 year:2015 number:1 day:15 month:12 pages:9-17
format_phy_str_mv	Article
institution	findex.gbv.de
topic_facet	Radiation toxicity Cranial irradiation Pseudoprogression Radiation necrosis Radiation pneumonitis Radiation fibrosis
dewey-raw	610
isfreeaccess_bool	false
container_title	Journal of radiation oncology
authorswithroles_txt_mv	Ning, Matthew S. @@aut@@ Kaminski, Joseph M. @@aut@@ Pucar, Darko @@aut@@ Shinohara, Eric T. @@aut@@
publishDateDaySort_date	2015-12-15T00:00:00Z
hierarchy_top_id	718611233
dewey-sort	3610
id	SPR031811698
language_de	englisch
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author	Ning, Matthew S.
spellingShingle	Ning, Matthew S. ddc 610 misc Radiation toxicity misc Cranial irradiation misc Pseudoprogression misc Radiation necrosis misc Radiation pneumonitis misc Radiation fibrosis Radiation emergencies: radiation-related brain and lung injury
authorStr	Ning, Matthew S.
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topic_title	610 ASE Radiation emergencies: radiation-related brain and lung injury Radiation toxicity (dpeaa)DE-He213 Cranial irradiation (dpeaa)DE-He213 Pseudoprogression (dpeaa)DE-He213 Radiation necrosis (dpeaa)DE-He213 Radiation pneumonitis (dpeaa)DE-He213 Radiation fibrosis (dpeaa)DE-He213
topic	ddc 610 misc Radiation toxicity misc Cranial irradiation misc Pseudoprogression misc Radiation necrosis misc Radiation pneumonitis misc Radiation fibrosis
topic_unstemmed	ddc 610 misc Radiation toxicity misc Cranial irradiation misc Pseudoprogression misc Radiation necrosis misc Radiation pneumonitis misc Radiation fibrosis
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title	Radiation emergencies: radiation-related brain and lung injury
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title_full	Radiation emergencies: radiation-related brain and lung injury
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author_browse	Ning, Matthew S. Kaminski, Joseph M. Pucar, Darko Shinohara, Eric T.
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title_sort	radiation emergencies: radiation-related brain and lung injury
title_auth	Radiation emergencies: radiation-related brain and lung injury
abstract	Background The advent of modern radiation techniques, such as intensity modulated and stereotactic ablative radiation therapy, has permitted increasingly accurate delivery of radiation, with ability to shape distribution of dose specifically to the tumor. These techniques limit dose to surrounding normal tissue in an effort to reduce toxicity; however, despite such improvements, potentially serious side effects related to treatment may occur, requiring urgent management. Objective Radiation-related brain or lung injury in previously irradiated patients may present in the acute or late post-treatment setting. Patients initially present with non-specific symptoms associated with the organ in question, representing a diagnostic challenge in the emergency room. Here, we review potential complications that may occur following radiation therapy to two commonly treated sites: brain and thorax. Conclusions We provide a guideline of the presentation, diagnosis, and management of these complications to function as a useful resource for healthcare providers. Furthermore, we review thedosimetric and volumetric parameters associated with such adverse events.
abstractGer	Background The advent of modern radiation techniques, such as intensity modulated and stereotactic ablative radiation therapy, has permitted increasingly accurate delivery of radiation, with ability to shape distribution of dose specifically to the tumor. These techniques limit dose to surrounding normal tissue in an effort to reduce toxicity; however, despite such improvements, potentially serious side effects related to treatment may occur, requiring urgent management. Objective Radiation-related brain or lung injury in previously irradiated patients may present in the acute or late post-treatment setting. Patients initially present with non-specific symptoms associated with the organ in question, representing a diagnostic challenge in the emergency room. Here, we review potential complications that may occur following radiation therapy to two commonly treated sites: brain and thorax. Conclusions We provide a guideline of the presentation, diagnosis, and management of these complications to function as a useful resource for healthcare providers. Furthermore, we review thedosimetric and volumetric parameters associated with such adverse events.
abstract_unstemmed	Background The advent of modern radiation techniques, such as intensity modulated and stereotactic ablative radiation therapy, has permitted increasingly accurate delivery of radiation, with ability to shape distribution of dose specifically to the tumor. These techniques limit dose to surrounding normal tissue in an effort to reduce toxicity; however, despite such improvements, potentially serious side effects related to treatment may occur, requiring urgent management. Objective Radiation-related brain or lung injury in previously irradiated patients may present in the acute or late post-treatment setting. Patients initially present with non-specific symptoms associated with the organ in question, representing a diagnostic challenge in the emergency room. Here, we review potential complications that may occur following radiation therapy to two commonly treated sites: brain and thorax. Conclusions We provide a guideline of the presentation, diagnosis, and management of these complications to function as a useful resource for healthcare providers. Furthermore, we review thedosimetric and volumetric parameters associated with such adverse events.
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container_issue	1
title_short	Radiation emergencies: radiation-related brain and lung injury
url	https://dx.doi.org/10.1007/s13566-015-0241-4
remote_bool	true
author2	Kaminski, Joseph M. Pucar, Darko Shinohara, Eric T.
author2Str	Kaminski, Joseph M. Pucar, Darko Shinohara, Eric T.
ppnlink	718611233
mediatype_str_mv	c
isOA_txt	false
hochschulschrift_bool	false
doi_str	10.1007/s13566-015-0241-4
up_date	2024-07-04T01:20:50.810Z
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