Reconstructed and real proton radiographs for image-guidance in proton beam therapy
Abstract One of the major challenges to proton beam therapy at this time is the uncertainty of the true range of a clinical treatment proton beam as it traverses the various tissues and organs in a human body. This uncertainty necessitates the addition of greater “margins” to the planning target vol...
Ausführliche Beschreibung
Autor*in: |
Miller, Chelsea [verfasserIn] Altoos, Basel [verfasserIn] DeJongh, Ethan A. [verfasserIn] Pankuch, Mark [verfasserIn] DeJongh, Don F. [verfasserIn] Rykalin, Victor [verfasserIn] Ordoñez, Caesar E. [verfasserIn] Karonis, Nicholas T. [verfasserIn] Winans, John R. [verfasserIn] Coutrakon, George [verfasserIn] Welsh, James S. [verfasserIn] |
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Format: |
E-Artikel |
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Sprache: |
Englisch |
Erschienen: |
2019 |
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Übergeordnetes Werk: |
Enthalten in: Journal of radiation oncology - Berlin : Springer, 2012, 8(2019), 1 vom: März, Seite 97-101 |
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Übergeordnetes Werk: |
volume:8 ; year:2019 ; number:1 ; month:03 ; pages:97-101 |
Links: |
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DOI / URN: |
10.1007/s13566-019-00376-0 |
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Katalog-ID: |
SPR031813259 |
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520 | |a Abstract One of the major challenges to proton beam therapy at this time is the uncertainty of the true range of a clinical treatment proton beam as it traverses the various tissues and organs in a human body. This uncertainty necessitates the addition of greater “margins” to the planning target volume along the direction of the beam to ensure safety and tumor target coverage. Proton radiography holds promise as both an image-guidance method for proton beam therapy and as a means of estimating particle beam range in the clinic. In this brief report, we present some of the first real and reconstructed proton radiographs using our particular system. Our qualitative review of these images indicates that this method has excellent potential as a proton radiography–based image-guidance system. Based on the encouraging results of our preliminary work, more rigorous and quantitative analyses will be performed shortly and we shall continue to explore the potential of this approach for addressing the particle beam range uncertainty issue. | ||
650 | 4 | |a Proton radiography |7 (dpeaa)DE-He213 | |
650 | 4 | |a Proton CT |7 (dpeaa)DE-He213 | |
650 | 4 | |a Particle beam therapy |7 (dpeaa)DE-He213 | |
650 | 4 | |a Range uncertainty |7 (dpeaa)DE-He213 | |
650 | 4 | |a Proton Image-Guidance |7 (dpeaa)DE-He213 | |
700 | 1 | |a Altoos, Basel |e verfasserin |4 aut | |
700 | 1 | |a DeJongh, Ethan A. |e verfasserin |4 aut | |
700 | 1 | |a Pankuch, Mark |e verfasserin |4 aut | |
700 | 1 | |a DeJongh, Don F. |e verfasserin |4 aut | |
700 | 1 | |a Rykalin, Victor |e verfasserin |4 aut | |
700 | 1 | |a Ordoñez, Caesar E. |e verfasserin |4 aut | |
700 | 1 | |a Karonis, Nicholas T. |e verfasserin |4 aut | |
700 | 1 | |a Winans, John R. |e verfasserin |4 aut | |
700 | 1 | |a Coutrakon, George |e verfasserin |4 aut | |
700 | 1 | |a Welsh, James S. |e verfasserin |4 aut | |
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10.1007/s13566-019-00376-0 doi (DE-627)SPR031813259 (SPR)s13566-019-00376-0-e DE-627 ger DE-627 rakwb eng 610 ASE Miller, Chelsea verfasserin aut Reconstructed and real proton radiographs for image-guidance in proton beam therapy 2019 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Abstract One of the major challenges to proton beam therapy at this time is the uncertainty of the true range of a clinical treatment proton beam as it traverses the various tissues and organs in a human body. This uncertainty necessitates the addition of greater “margins” to the planning target volume along the direction of the beam to ensure safety and tumor target coverage. Proton radiography holds promise as both an image-guidance method for proton beam therapy and as a means of estimating particle beam range in the clinic. In this brief report, we present some of the first real and reconstructed proton radiographs using our particular system. Our qualitative review of these images indicates that this method has excellent potential as a proton radiography–based image-guidance system. Based on the encouraging results of our preliminary work, more rigorous and quantitative analyses will be performed shortly and we shall continue to explore the potential of this approach for addressing the particle beam range uncertainty issue. Proton radiography (dpeaa)DE-He213 Proton CT (dpeaa)DE-He213 Particle beam therapy (dpeaa)DE-He213 Range uncertainty (dpeaa)DE-He213 Proton Image-Guidance (dpeaa)DE-He213 Altoos, Basel verfasserin aut DeJongh, Ethan A. verfasserin aut Pankuch, Mark verfasserin aut DeJongh, Don F. verfasserin aut Rykalin, Victor verfasserin aut Ordoñez, Caesar E. verfasserin aut Karonis, Nicholas T. verfasserin aut Winans, John R. verfasserin aut Coutrakon, George verfasserin aut Welsh, James S. verfasserin aut Enthalten in Journal of radiation oncology Berlin : Springer, 2012 8(2019), 1 vom: März, Seite 97-101 (DE-627)718611233 (DE-600)2660511-9 1948-7908 nnns volume:8 year:2019 number:1 month:03 pages:97-101 https://dx.doi.org/10.1007/s13566-019-00376-0 lizenzpflichtig Volltext GBV_USEFLAG_A SYSFLAG_A GBV_SPRINGER SSG-OLC-PHA GBV_ILN_11 GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_32 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_70 GBV_ILN_73 GBV_ILN_74 GBV_ILN_90 GBV_ILN_95 GBV_ILN_100 GBV_ILN_101 GBV_ILN_105 GBV_ILN_110 GBV_ILN_120 GBV_ILN_138 GBV_ILN_150 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_171 GBV_ILN_187 GBV_ILN_213 GBV_ILN_224 GBV_ILN_230 GBV_ILN_250 GBV_ILN_281 GBV_ILN_285 GBV_ILN_293 GBV_ILN_370 GBV_ILN_602 GBV_ILN_636 GBV_ILN_702 GBV_ILN_2001 GBV_ILN_2003 GBV_ILN_2004 GBV_ILN_2005 GBV_ILN_2006 GBV_ILN_2007 GBV_ILN_2008 GBV_ILN_2009 GBV_ILN_2010 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2015 GBV_ILN_2020 GBV_ILN_2021 GBV_ILN_2025 GBV_ILN_2026 GBV_ILN_2027 GBV_ILN_2031 GBV_ILN_2034 GBV_ILN_2037 GBV_ILN_2038 GBV_ILN_2039 GBV_ILN_2044 GBV_ILN_2048 GBV_ILN_2049 GBV_ILN_2050 GBV_ILN_2055 GBV_ILN_2057 GBV_ILN_2059 GBV_ILN_2061 GBV_ILN_2064 GBV_ILN_2065 GBV_ILN_2068 GBV_ILN_2070 GBV_ILN_2086 GBV_ILN_2088 GBV_ILN_2093 GBV_ILN_2106 GBV_ILN_2107 GBV_ILN_2108 GBV_ILN_2110 GBV_ILN_2111 GBV_ILN_2112 GBV_ILN_2113 GBV_ILN_2116 GBV_ILN_2118 GBV_ILN_2119 GBV_ILN_2122 GBV_ILN_2129 GBV_ILN_2143 GBV_ILN_2144 GBV_ILN_2147 GBV_ILN_2148 GBV_ILN_2152 GBV_ILN_2153 GBV_ILN_2188 GBV_ILN_2232 GBV_ILN_2336 GBV_ILN_2446 GBV_ILN_2470 GBV_ILN_2472 GBV_ILN_2507 GBV_ILN_2522 GBV_ILN_2548 GBV_ILN_4035 GBV_ILN_4037 GBV_ILN_4046 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4242 GBV_ILN_4246 GBV_ILN_4249 GBV_ILN_4251 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4326 GBV_ILN_4333 GBV_ILN_4334 GBV_ILN_4335 GBV_ILN_4336 GBV_ILN_4338 GBV_ILN_4393 GBV_ILN_4700 AR 8 2019 1 03 97-101 |
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10.1007/s13566-019-00376-0 doi (DE-627)SPR031813259 (SPR)s13566-019-00376-0-e DE-627 ger DE-627 rakwb eng 610 ASE Miller, Chelsea verfasserin aut Reconstructed and real proton radiographs for image-guidance in proton beam therapy 2019 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Abstract One of the major challenges to proton beam therapy at this time is the uncertainty of the true range of a clinical treatment proton beam as it traverses the various tissues and organs in a human body. This uncertainty necessitates the addition of greater “margins” to the planning target volume along the direction of the beam to ensure safety and tumor target coverage. Proton radiography holds promise as both an image-guidance method for proton beam therapy and as a means of estimating particle beam range in the clinic. In this brief report, we present some of the first real and reconstructed proton radiographs using our particular system. Our qualitative review of these images indicates that this method has excellent potential as a proton radiography–based image-guidance system. Based on the encouraging results of our preliminary work, more rigorous and quantitative analyses will be performed shortly and we shall continue to explore the potential of this approach for addressing the particle beam range uncertainty issue. Proton radiography (dpeaa)DE-He213 Proton CT (dpeaa)DE-He213 Particle beam therapy (dpeaa)DE-He213 Range uncertainty (dpeaa)DE-He213 Proton Image-Guidance (dpeaa)DE-He213 Altoos, Basel verfasserin aut DeJongh, Ethan A. verfasserin aut Pankuch, Mark verfasserin aut DeJongh, Don F. verfasserin aut Rykalin, Victor verfasserin aut Ordoñez, Caesar E. verfasserin aut Karonis, Nicholas T. verfasserin aut Winans, John R. verfasserin aut Coutrakon, George verfasserin aut Welsh, James S. verfasserin aut Enthalten in Journal of radiation oncology Berlin : Springer, 2012 8(2019), 1 vom: März, Seite 97-101 (DE-627)718611233 (DE-600)2660511-9 1948-7908 nnns volume:8 year:2019 number:1 month:03 pages:97-101 https://dx.doi.org/10.1007/s13566-019-00376-0 lizenzpflichtig Volltext GBV_USEFLAG_A SYSFLAG_A GBV_SPRINGER SSG-OLC-PHA GBV_ILN_11 GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_32 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_70 GBV_ILN_73 GBV_ILN_74 GBV_ILN_90 GBV_ILN_95 GBV_ILN_100 GBV_ILN_101 GBV_ILN_105 GBV_ILN_110 GBV_ILN_120 GBV_ILN_138 GBV_ILN_150 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_171 GBV_ILN_187 GBV_ILN_213 GBV_ILN_224 GBV_ILN_230 GBV_ILN_250 GBV_ILN_281 GBV_ILN_285 GBV_ILN_293 GBV_ILN_370 GBV_ILN_602 GBV_ILN_636 GBV_ILN_702 GBV_ILN_2001 GBV_ILN_2003 GBV_ILN_2004 GBV_ILN_2005 GBV_ILN_2006 GBV_ILN_2007 GBV_ILN_2008 GBV_ILN_2009 GBV_ILN_2010 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2015 GBV_ILN_2020 GBV_ILN_2021 GBV_ILN_2025 GBV_ILN_2026 GBV_ILN_2027 GBV_ILN_2031 GBV_ILN_2034 GBV_ILN_2037 GBV_ILN_2038 GBV_ILN_2039 GBV_ILN_2044 GBV_ILN_2048 GBV_ILN_2049 GBV_ILN_2050 GBV_ILN_2055 GBV_ILN_2057 GBV_ILN_2059 GBV_ILN_2061 GBV_ILN_2064 GBV_ILN_2065 GBV_ILN_2068 GBV_ILN_2070 GBV_ILN_2086 GBV_ILN_2088 GBV_ILN_2093 GBV_ILN_2106 GBV_ILN_2107 GBV_ILN_2108 GBV_ILN_2110 GBV_ILN_2111 GBV_ILN_2112 GBV_ILN_2113 GBV_ILN_2116 GBV_ILN_2118 GBV_ILN_2119 GBV_ILN_2122 GBV_ILN_2129 GBV_ILN_2143 GBV_ILN_2144 GBV_ILN_2147 GBV_ILN_2148 GBV_ILN_2152 GBV_ILN_2153 GBV_ILN_2188 GBV_ILN_2232 GBV_ILN_2336 GBV_ILN_2446 GBV_ILN_2470 GBV_ILN_2472 GBV_ILN_2507 GBV_ILN_2522 GBV_ILN_2548 GBV_ILN_4035 GBV_ILN_4037 GBV_ILN_4046 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4242 GBV_ILN_4246 GBV_ILN_4249 GBV_ILN_4251 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4326 GBV_ILN_4333 GBV_ILN_4334 GBV_ILN_4335 GBV_ILN_4336 GBV_ILN_4338 GBV_ILN_4393 GBV_ILN_4700 AR 8 2019 1 03 97-101 |
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10.1007/s13566-019-00376-0 doi (DE-627)SPR031813259 (SPR)s13566-019-00376-0-e DE-627 ger DE-627 rakwb eng 610 ASE Miller, Chelsea verfasserin aut Reconstructed and real proton radiographs for image-guidance in proton beam therapy 2019 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Abstract One of the major challenges to proton beam therapy at this time is the uncertainty of the true range of a clinical treatment proton beam as it traverses the various tissues and organs in a human body. This uncertainty necessitates the addition of greater “margins” to the planning target volume along the direction of the beam to ensure safety and tumor target coverage. Proton radiography holds promise as both an image-guidance method for proton beam therapy and as a means of estimating particle beam range in the clinic. In this brief report, we present some of the first real and reconstructed proton radiographs using our particular system. Our qualitative review of these images indicates that this method has excellent potential as a proton radiography–based image-guidance system. Based on the encouraging results of our preliminary work, more rigorous and quantitative analyses will be performed shortly and we shall continue to explore the potential of this approach for addressing the particle beam range uncertainty issue. Proton radiography (dpeaa)DE-He213 Proton CT (dpeaa)DE-He213 Particle beam therapy (dpeaa)DE-He213 Range uncertainty (dpeaa)DE-He213 Proton Image-Guidance (dpeaa)DE-He213 Altoos, Basel verfasserin aut DeJongh, Ethan A. verfasserin aut Pankuch, Mark verfasserin aut DeJongh, Don F. verfasserin aut Rykalin, Victor verfasserin aut Ordoñez, Caesar E. verfasserin aut Karonis, Nicholas T. verfasserin aut Winans, John R. verfasserin aut Coutrakon, George verfasserin aut Welsh, James S. verfasserin aut Enthalten in Journal of radiation oncology Berlin : Springer, 2012 8(2019), 1 vom: März, Seite 97-101 (DE-627)718611233 (DE-600)2660511-9 1948-7908 nnns volume:8 year:2019 number:1 month:03 pages:97-101 https://dx.doi.org/10.1007/s13566-019-00376-0 lizenzpflichtig Volltext GBV_USEFLAG_A SYSFLAG_A GBV_SPRINGER SSG-OLC-PHA GBV_ILN_11 GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_32 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_70 GBV_ILN_73 GBV_ILN_74 GBV_ILN_90 GBV_ILN_95 GBV_ILN_100 GBV_ILN_101 GBV_ILN_105 GBV_ILN_110 GBV_ILN_120 GBV_ILN_138 GBV_ILN_150 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_171 GBV_ILN_187 GBV_ILN_213 GBV_ILN_224 GBV_ILN_230 GBV_ILN_250 GBV_ILN_281 GBV_ILN_285 GBV_ILN_293 GBV_ILN_370 GBV_ILN_602 GBV_ILN_636 GBV_ILN_702 GBV_ILN_2001 GBV_ILN_2003 GBV_ILN_2004 GBV_ILN_2005 GBV_ILN_2006 GBV_ILN_2007 GBV_ILN_2008 GBV_ILN_2009 GBV_ILN_2010 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2015 GBV_ILN_2020 GBV_ILN_2021 GBV_ILN_2025 GBV_ILN_2026 GBV_ILN_2027 GBV_ILN_2031 GBV_ILN_2034 GBV_ILN_2037 GBV_ILN_2038 GBV_ILN_2039 GBV_ILN_2044 GBV_ILN_2048 GBV_ILN_2049 GBV_ILN_2050 GBV_ILN_2055 GBV_ILN_2057 GBV_ILN_2059 GBV_ILN_2061 GBV_ILN_2064 GBV_ILN_2065 GBV_ILN_2068 GBV_ILN_2070 GBV_ILN_2086 GBV_ILN_2088 GBV_ILN_2093 GBV_ILN_2106 GBV_ILN_2107 GBV_ILN_2108 GBV_ILN_2110 GBV_ILN_2111 GBV_ILN_2112 GBV_ILN_2113 GBV_ILN_2116 GBV_ILN_2118 GBV_ILN_2119 GBV_ILN_2122 GBV_ILN_2129 GBV_ILN_2143 GBV_ILN_2144 GBV_ILN_2147 GBV_ILN_2148 GBV_ILN_2152 GBV_ILN_2153 GBV_ILN_2188 GBV_ILN_2232 GBV_ILN_2336 GBV_ILN_2446 GBV_ILN_2470 GBV_ILN_2472 GBV_ILN_2507 GBV_ILN_2522 GBV_ILN_2548 GBV_ILN_4035 GBV_ILN_4037 GBV_ILN_4046 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4242 GBV_ILN_4246 GBV_ILN_4249 GBV_ILN_4251 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4326 GBV_ILN_4333 GBV_ILN_4334 GBV_ILN_4335 GBV_ILN_4336 GBV_ILN_4338 GBV_ILN_4393 GBV_ILN_4700 AR 8 2019 1 03 97-101 |
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10.1007/s13566-019-00376-0 doi (DE-627)SPR031813259 (SPR)s13566-019-00376-0-e DE-627 ger DE-627 rakwb eng 610 ASE Miller, Chelsea verfasserin aut Reconstructed and real proton radiographs for image-guidance in proton beam therapy 2019 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Abstract One of the major challenges to proton beam therapy at this time is the uncertainty of the true range of a clinical treatment proton beam as it traverses the various tissues and organs in a human body. This uncertainty necessitates the addition of greater “margins” to the planning target volume along the direction of the beam to ensure safety and tumor target coverage. Proton radiography holds promise as both an image-guidance method for proton beam therapy and as a means of estimating particle beam range in the clinic. In this brief report, we present some of the first real and reconstructed proton radiographs using our particular system. Our qualitative review of these images indicates that this method has excellent potential as a proton radiography–based image-guidance system. Based on the encouraging results of our preliminary work, more rigorous and quantitative analyses will be performed shortly and we shall continue to explore the potential of this approach for addressing the particle beam range uncertainty issue. Proton radiography (dpeaa)DE-He213 Proton CT (dpeaa)DE-He213 Particle beam therapy (dpeaa)DE-He213 Range uncertainty (dpeaa)DE-He213 Proton Image-Guidance (dpeaa)DE-He213 Altoos, Basel verfasserin aut DeJongh, Ethan A. verfasserin aut Pankuch, Mark verfasserin aut DeJongh, Don F. verfasserin aut Rykalin, Victor verfasserin aut Ordoñez, Caesar E. verfasserin aut Karonis, Nicholas T. verfasserin aut Winans, John R. verfasserin aut Coutrakon, George verfasserin aut Welsh, James S. verfasserin aut Enthalten in Journal of radiation oncology Berlin : Springer, 2012 8(2019), 1 vom: März, Seite 97-101 (DE-627)718611233 (DE-600)2660511-9 1948-7908 nnns volume:8 year:2019 number:1 month:03 pages:97-101 https://dx.doi.org/10.1007/s13566-019-00376-0 lizenzpflichtig Volltext GBV_USEFLAG_A SYSFLAG_A GBV_SPRINGER SSG-OLC-PHA GBV_ILN_11 GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_32 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_70 GBV_ILN_73 GBV_ILN_74 GBV_ILN_90 GBV_ILN_95 GBV_ILN_100 GBV_ILN_101 GBV_ILN_105 GBV_ILN_110 GBV_ILN_120 GBV_ILN_138 GBV_ILN_150 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_171 GBV_ILN_187 GBV_ILN_213 GBV_ILN_224 GBV_ILN_230 GBV_ILN_250 GBV_ILN_281 GBV_ILN_285 GBV_ILN_293 GBV_ILN_370 GBV_ILN_602 GBV_ILN_636 GBV_ILN_702 GBV_ILN_2001 GBV_ILN_2003 GBV_ILN_2004 GBV_ILN_2005 GBV_ILN_2006 GBV_ILN_2007 GBV_ILN_2008 GBV_ILN_2009 GBV_ILN_2010 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2015 GBV_ILN_2020 GBV_ILN_2021 GBV_ILN_2025 GBV_ILN_2026 GBV_ILN_2027 GBV_ILN_2031 GBV_ILN_2034 GBV_ILN_2037 GBV_ILN_2038 GBV_ILN_2039 GBV_ILN_2044 GBV_ILN_2048 GBV_ILN_2049 GBV_ILN_2050 GBV_ILN_2055 GBV_ILN_2057 GBV_ILN_2059 GBV_ILN_2061 GBV_ILN_2064 GBV_ILN_2065 GBV_ILN_2068 GBV_ILN_2070 GBV_ILN_2086 GBV_ILN_2088 GBV_ILN_2093 GBV_ILN_2106 GBV_ILN_2107 GBV_ILN_2108 GBV_ILN_2110 GBV_ILN_2111 GBV_ILN_2112 GBV_ILN_2113 GBV_ILN_2116 GBV_ILN_2118 GBV_ILN_2119 GBV_ILN_2122 GBV_ILN_2129 GBV_ILN_2143 GBV_ILN_2144 GBV_ILN_2147 GBV_ILN_2148 GBV_ILN_2152 GBV_ILN_2153 GBV_ILN_2188 GBV_ILN_2232 GBV_ILN_2336 GBV_ILN_2446 GBV_ILN_2470 GBV_ILN_2472 GBV_ILN_2507 GBV_ILN_2522 GBV_ILN_2548 GBV_ILN_4035 GBV_ILN_4037 GBV_ILN_4046 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4242 GBV_ILN_4246 GBV_ILN_4249 GBV_ILN_4251 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4326 GBV_ILN_4333 GBV_ILN_4334 GBV_ILN_4335 GBV_ILN_4336 GBV_ILN_4338 GBV_ILN_4393 GBV_ILN_4700 AR 8 2019 1 03 97-101 |
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10.1007/s13566-019-00376-0 doi (DE-627)SPR031813259 (SPR)s13566-019-00376-0-e DE-627 ger DE-627 rakwb eng 610 ASE Miller, Chelsea verfasserin aut Reconstructed and real proton radiographs for image-guidance in proton beam therapy 2019 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Abstract One of the major challenges to proton beam therapy at this time is the uncertainty of the true range of a clinical treatment proton beam as it traverses the various tissues and organs in a human body. This uncertainty necessitates the addition of greater “margins” to the planning target volume along the direction of the beam to ensure safety and tumor target coverage. Proton radiography holds promise as both an image-guidance method for proton beam therapy and as a means of estimating particle beam range in the clinic. In this brief report, we present some of the first real and reconstructed proton radiographs using our particular system. Our qualitative review of these images indicates that this method has excellent potential as a proton radiography–based image-guidance system. Based on the encouraging results of our preliminary work, more rigorous and quantitative analyses will be performed shortly and we shall continue to explore the potential of this approach for addressing the particle beam range uncertainty issue. Proton radiography (dpeaa)DE-He213 Proton CT (dpeaa)DE-He213 Particle beam therapy (dpeaa)DE-He213 Range uncertainty (dpeaa)DE-He213 Proton Image-Guidance (dpeaa)DE-He213 Altoos, Basel verfasserin aut DeJongh, Ethan A. verfasserin aut Pankuch, Mark verfasserin aut DeJongh, Don F. verfasserin aut Rykalin, Victor verfasserin aut Ordoñez, Caesar E. verfasserin aut Karonis, Nicholas T. verfasserin aut Winans, John R. verfasserin aut Coutrakon, George verfasserin aut Welsh, James S. verfasserin aut Enthalten in Journal of radiation oncology Berlin : Springer, 2012 8(2019), 1 vom: März, Seite 97-101 (DE-627)718611233 (DE-600)2660511-9 1948-7908 nnns volume:8 year:2019 number:1 month:03 pages:97-101 https://dx.doi.org/10.1007/s13566-019-00376-0 lizenzpflichtig Volltext GBV_USEFLAG_A SYSFLAG_A GBV_SPRINGER SSG-OLC-PHA GBV_ILN_11 GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_32 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_70 GBV_ILN_73 GBV_ILN_74 GBV_ILN_90 GBV_ILN_95 GBV_ILN_100 GBV_ILN_101 GBV_ILN_105 GBV_ILN_110 GBV_ILN_120 GBV_ILN_138 GBV_ILN_150 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_171 GBV_ILN_187 GBV_ILN_213 GBV_ILN_224 GBV_ILN_230 GBV_ILN_250 GBV_ILN_281 GBV_ILN_285 GBV_ILN_293 GBV_ILN_370 GBV_ILN_602 GBV_ILN_636 GBV_ILN_702 GBV_ILN_2001 GBV_ILN_2003 GBV_ILN_2004 GBV_ILN_2005 GBV_ILN_2006 GBV_ILN_2007 GBV_ILN_2008 GBV_ILN_2009 GBV_ILN_2010 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2015 GBV_ILN_2020 GBV_ILN_2021 GBV_ILN_2025 GBV_ILN_2026 GBV_ILN_2027 GBV_ILN_2031 GBV_ILN_2034 GBV_ILN_2037 GBV_ILN_2038 GBV_ILN_2039 GBV_ILN_2044 GBV_ILN_2048 GBV_ILN_2049 GBV_ILN_2050 GBV_ILN_2055 GBV_ILN_2057 GBV_ILN_2059 GBV_ILN_2061 GBV_ILN_2064 GBV_ILN_2065 GBV_ILN_2068 GBV_ILN_2070 GBV_ILN_2086 GBV_ILN_2088 GBV_ILN_2093 GBV_ILN_2106 GBV_ILN_2107 GBV_ILN_2108 GBV_ILN_2110 GBV_ILN_2111 GBV_ILN_2112 GBV_ILN_2113 GBV_ILN_2116 GBV_ILN_2118 GBV_ILN_2119 GBV_ILN_2122 GBV_ILN_2129 GBV_ILN_2143 GBV_ILN_2144 GBV_ILN_2147 GBV_ILN_2148 GBV_ILN_2152 GBV_ILN_2153 GBV_ILN_2188 GBV_ILN_2232 GBV_ILN_2336 GBV_ILN_2446 GBV_ILN_2470 GBV_ILN_2472 GBV_ILN_2507 GBV_ILN_2522 GBV_ILN_2548 GBV_ILN_4035 GBV_ILN_4037 GBV_ILN_4046 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4242 GBV_ILN_4246 GBV_ILN_4249 GBV_ILN_4251 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4326 GBV_ILN_4333 GBV_ILN_4334 GBV_ILN_4335 GBV_ILN_4336 GBV_ILN_4338 GBV_ILN_4393 GBV_ILN_4700 AR 8 2019 1 03 97-101 |
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Enthalten in Journal of radiation oncology 8(2019), 1 vom: März, Seite 97-101 volume:8 year:2019 number:1 month:03 pages:97-101 |
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Proton radiography Proton CT Particle beam therapy Range uncertainty Proton Image-Guidance |
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Miller, Chelsea @@aut@@ Altoos, Basel @@aut@@ DeJongh, Ethan A. @@aut@@ Pankuch, Mark @@aut@@ DeJongh, Don F. @@aut@@ Rykalin, Victor @@aut@@ Ordoñez, Caesar E. @@aut@@ Karonis, Nicholas T. @@aut@@ Winans, John R. @@aut@@ Coutrakon, George @@aut@@ Welsh, James S. @@aut@@ |
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Miller, Chelsea |
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610 ASE Reconstructed and real proton radiographs for image-guidance in proton beam therapy Proton radiography (dpeaa)DE-He213 Proton CT (dpeaa)DE-He213 Particle beam therapy (dpeaa)DE-He213 Range uncertainty (dpeaa)DE-He213 Proton Image-Guidance (dpeaa)DE-He213 |
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Reconstructed and real proton radiographs for image-guidance in proton beam therapy |
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Miller, Chelsea Altoos, Basel DeJongh, Ethan A. Pankuch, Mark DeJongh, Don F. Rykalin, Victor Ordoñez, Caesar E. Karonis, Nicholas T. Winans, John R. Coutrakon, George Welsh, James S. |
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reconstructed and real proton radiographs for image-guidance in proton beam therapy |
title_auth |
Reconstructed and real proton radiographs for image-guidance in proton beam therapy |
abstract |
Abstract One of the major challenges to proton beam therapy at this time is the uncertainty of the true range of a clinical treatment proton beam as it traverses the various tissues and organs in a human body. This uncertainty necessitates the addition of greater “margins” to the planning target volume along the direction of the beam to ensure safety and tumor target coverage. Proton radiography holds promise as both an image-guidance method for proton beam therapy and as a means of estimating particle beam range in the clinic. In this brief report, we present some of the first real and reconstructed proton radiographs using our particular system. Our qualitative review of these images indicates that this method has excellent potential as a proton radiography–based image-guidance system. Based on the encouraging results of our preliminary work, more rigorous and quantitative analyses will be performed shortly and we shall continue to explore the potential of this approach for addressing the particle beam range uncertainty issue. |
abstractGer |
Abstract One of the major challenges to proton beam therapy at this time is the uncertainty of the true range of a clinical treatment proton beam as it traverses the various tissues and organs in a human body. This uncertainty necessitates the addition of greater “margins” to the planning target volume along the direction of the beam to ensure safety and tumor target coverage. Proton radiography holds promise as both an image-guidance method for proton beam therapy and as a means of estimating particle beam range in the clinic. In this brief report, we present some of the first real and reconstructed proton radiographs using our particular system. Our qualitative review of these images indicates that this method has excellent potential as a proton radiography–based image-guidance system. Based on the encouraging results of our preliminary work, more rigorous and quantitative analyses will be performed shortly and we shall continue to explore the potential of this approach for addressing the particle beam range uncertainty issue. |
abstract_unstemmed |
Abstract One of the major challenges to proton beam therapy at this time is the uncertainty of the true range of a clinical treatment proton beam as it traverses the various tissues and organs in a human body. This uncertainty necessitates the addition of greater “margins” to the planning target volume along the direction of the beam to ensure safety and tumor target coverage. Proton radiography holds promise as both an image-guidance method for proton beam therapy and as a means of estimating particle beam range in the clinic. In this brief report, we present some of the first real and reconstructed proton radiographs using our particular system. Our qualitative review of these images indicates that this method has excellent potential as a proton radiography–based image-guidance system. Based on the encouraging results of our preliminary work, more rigorous and quantitative analyses will be performed shortly and we shall continue to explore the potential of this approach for addressing the particle beam range uncertainty issue. |
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1 |
title_short |
Reconstructed and real proton radiographs for image-guidance in proton beam therapy |
url |
https://dx.doi.org/10.1007/s13566-019-00376-0 |
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author2 |
Altoos, Basel DeJongh, Ethan A. Pankuch, Mark DeJongh, Don F. Rykalin, Victor Ordoñez, Caesar E. Karonis, Nicholas T. Winans, John R. Coutrakon, George Welsh, James S. |
author2Str |
Altoos, Basel DeJongh, Ethan A. Pankuch, Mark DeJongh, Don F. Rykalin, Victor Ordoñez, Caesar E. Karonis, Nicholas T. Winans, John R. Coutrakon, George Welsh, James S. |
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doi_str |
10.1007/s13566-019-00376-0 |
up_date |
2024-07-04T01:21:20.768Z |
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|
score |
7.398162 |