Antimicrobial peptides and proteins of the horse - insights into a well-armed organism

Abstract Antimicrobial peptides play a pivotal role as key effectors of the innate immune system in plants and animals and act as endogenous antibiotics. The molecules exhibit an antimicrobial activity against bacteria, viruses, and eukaryotic pathogens with different specificities and potencies dep...
Ausführliche Beschreibung

Gespeichert in:

Autor*in:	Bruhn, Oliver [verfasserIn] Grötzinger, Joachim [verfasserIn] Cascorbi, Ingolf [verfasserIn] Jung, Sascha [verfasserIn]

Format:	E-Artikel
Sprache:	Englisch

Erschienen:	2011

Schlagwörter:	Antimicrobial Activity Lysozyme Acne Antimicrobial Peptide Paneth Cell

Übergeordnetes Werk:	Enthalten in: Veterinary research - London : BioMed Central, 1993, 42(2011), 1 vom: 02. Sept.
Übergeordnetes Werk:	volume:42 ; year:2011 ; number:1 ; day:02 ; month:09

Links:	Volltext

DOI / URN:	10.1186/1297-9716-42-98

Katalog-ID:	SPR031814913

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spelling	10.1186/1297-9716-42-98 doi (DE-627)SPR031814913 (SPR)1297-9716-42-98-e DE-627 ger DE-627 rakwb eng 630 640 ASE 46.00 bkl Bruhn, Oliver verfasserin aut Antimicrobial peptides and proteins of the horse - insights into a well-armed organism 2011 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Abstract Antimicrobial peptides play a pivotal role as key effectors of the innate immune system in plants and animals and act as endogenous antibiotics. The molecules exhibit an antimicrobial activity against bacteria, viruses, and eukaryotic pathogens with different specificities and potencies depending on the structure and amino-acid composition of the peptides. Several antimicrobial peptides were comprehensively investigated in the last three decades and some molecules with remarkable antimicrobial properties have reached the third phase of clinical studies. Next to the peptides themselves, numerous organisms were examined and analyzed regarding their repertoire of antimicrobial peptides revealing a huge number of candidates with potencies and properties for future medical applications. One of these organisms is the horse, which possesses numerous peptides that are interesting candidates for therapeutical applications in veterinary medicine. Here we summarize investigations and knowledge on equine antimicrobial peptides, point to interesting candidates, and discuss prospects for therapeutical applications. Antimicrobial Activity (dpeaa)DE-He213 Lysozyme (dpeaa)DE-He213 Acne (dpeaa)DE-He213 Antimicrobial Peptide (dpeaa)DE-He213 Paneth Cell (dpeaa)DE-He213 Grötzinger, Joachim verfasserin aut Cascorbi, Ingolf verfasserin aut Jung, Sascha verfasserin aut Enthalten in Veterinary research London : BioMed Central, 1993 42(2011), 1 vom: 02. Sept. (DE-627)312853653 (DE-600)2012391-7 1297-9716 nnns volume:42 year:2011 number:1 day:02 month:09 https://dx.doi.org/10.1186/1297-9716-42-98 kostenfrei Volltext GBV_USEFLAG_A SYSFLAG_A GBV_SPRINGER GBV_ILN_11 GBV_ILN_20 GBV_ILN_22 GBV_ILN_24 GBV_ILN_31 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_70 GBV_ILN_73 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_213 GBV_ILN_230 GBV_ILN_252 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_2003 GBV_ILN_2014 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 46.00 ASE AR 42 2011 1 02 09
allfields_unstemmed	10.1186/1297-9716-42-98 doi (DE-627)SPR031814913 (SPR)1297-9716-42-98-e DE-627 ger DE-627 rakwb eng 630 640 ASE 46.00 bkl Bruhn, Oliver verfasserin aut Antimicrobial peptides and proteins of the horse - insights into a well-armed organism 2011 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Abstract Antimicrobial peptides play a pivotal role as key effectors of the innate immune system in plants and animals and act as endogenous antibiotics. The molecules exhibit an antimicrobial activity against bacteria, viruses, and eukaryotic pathogens with different specificities and potencies depending on the structure and amino-acid composition of the peptides. Several antimicrobial peptides were comprehensively investigated in the last three decades and some molecules with remarkable antimicrobial properties have reached the third phase of clinical studies. Next to the peptides themselves, numerous organisms were examined and analyzed regarding their repertoire of antimicrobial peptides revealing a huge number of candidates with potencies and properties for future medical applications. One of these organisms is the horse, which possesses numerous peptides that are interesting candidates for therapeutical applications in veterinary medicine. Here we summarize investigations and knowledge on equine antimicrobial peptides, point to interesting candidates, and discuss prospects for therapeutical applications. Antimicrobial Activity (dpeaa)DE-He213 Lysozyme (dpeaa)DE-He213 Acne (dpeaa)DE-He213 Antimicrobial Peptide (dpeaa)DE-He213 Paneth Cell (dpeaa)DE-He213 Grötzinger, Joachim verfasserin aut Cascorbi, Ingolf verfasserin aut Jung, Sascha verfasserin aut Enthalten in Veterinary research London : BioMed Central, 1993 42(2011), 1 vom: 02. Sept. (DE-627)312853653 (DE-600)2012391-7 1297-9716 nnns volume:42 year:2011 number:1 day:02 month:09 https://dx.doi.org/10.1186/1297-9716-42-98 kostenfrei Volltext GBV_USEFLAG_A SYSFLAG_A GBV_SPRINGER GBV_ILN_11 GBV_ILN_20 GBV_ILN_22 GBV_ILN_24 GBV_ILN_31 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_70 GBV_ILN_73 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_213 GBV_ILN_230 GBV_ILN_252 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_2003 GBV_ILN_2014 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 46.00 ASE AR 42 2011 1 02 09
allfieldsGer	10.1186/1297-9716-42-98 doi (DE-627)SPR031814913 (SPR)1297-9716-42-98-e DE-627 ger DE-627 rakwb eng 630 640 ASE 46.00 bkl Bruhn, Oliver verfasserin aut Antimicrobial peptides and proteins of the horse - insights into a well-armed organism 2011 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Abstract Antimicrobial peptides play a pivotal role as key effectors of the innate immune system in plants and animals and act as endogenous antibiotics. The molecules exhibit an antimicrobial activity against bacteria, viruses, and eukaryotic pathogens with different specificities and potencies depending on the structure and amino-acid composition of the peptides. Several antimicrobial peptides were comprehensively investigated in the last three decades and some molecules with remarkable antimicrobial properties have reached the third phase of clinical studies. Next to the peptides themselves, numerous organisms were examined and analyzed regarding their repertoire of antimicrobial peptides revealing a huge number of candidates with potencies and properties for future medical applications. One of these organisms is the horse, which possesses numerous peptides that are interesting candidates for therapeutical applications in veterinary medicine. Here we summarize investigations and knowledge on equine antimicrobial peptides, point to interesting candidates, and discuss prospects for therapeutical applications. Antimicrobial Activity (dpeaa)DE-He213 Lysozyme (dpeaa)DE-He213 Acne (dpeaa)DE-He213 Antimicrobial Peptide (dpeaa)DE-He213 Paneth Cell (dpeaa)DE-He213 Grötzinger, Joachim verfasserin aut Cascorbi, Ingolf verfasserin aut Jung, Sascha verfasserin aut Enthalten in Veterinary research London : BioMed Central, 1993 42(2011), 1 vom: 02. Sept. (DE-627)312853653 (DE-600)2012391-7 1297-9716 nnns volume:42 year:2011 number:1 day:02 month:09 https://dx.doi.org/10.1186/1297-9716-42-98 kostenfrei Volltext GBV_USEFLAG_A SYSFLAG_A GBV_SPRINGER GBV_ILN_11 GBV_ILN_20 GBV_ILN_22 GBV_ILN_24 GBV_ILN_31 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_70 GBV_ILN_73 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_213 GBV_ILN_230 GBV_ILN_252 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_2003 GBV_ILN_2014 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 46.00 ASE AR 42 2011 1 02 09
allfieldsSound	10.1186/1297-9716-42-98 doi (DE-627)SPR031814913 (SPR)1297-9716-42-98-e DE-627 ger DE-627 rakwb eng 630 640 ASE 46.00 bkl Bruhn, Oliver verfasserin aut Antimicrobial peptides and proteins of the horse - insights into a well-armed organism 2011 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Abstract Antimicrobial peptides play a pivotal role as key effectors of the innate immune system in plants and animals and act as endogenous antibiotics. The molecules exhibit an antimicrobial activity against bacteria, viruses, and eukaryotic pathogens with different specificities and potencies depending on the structure and amino-acid composition of the peptides. Several antimicrobial peptides were comprehensively investigated in the last three decades and some molecules with remarkable antimicrobial properties have reached the third phase of clinical studies. Next to the peptides themselves, numerous organisms were examined and analyzed regarding their repertoire of antimicrobial peptides revealing a huge number of candidates with potencies and properties for future medical applications. One of these organisms is the horse, which possesses numerous peptides that are interesting candidates for therapeutical applications in veterinary medicine. Here we summarize investigations and knowledge on equine antimicrobial peptides, point to interesting candidates, and discuss prospects for therapeutical applications. Antimicrobial Activity (dpeaa)DE-He213 Lysozyme (dpeaa)DE-He213 Acne (dpeaa)DE-He213 Antimicrobial Peptide (dpeaa)DE-He213 Paneth Cell (dpeaa)DE-He213 Grötzinger, Joachim verfasserin aut Cascorbi, Ingolf verfasserin aut Jung, Sascha verfasserin aut Enthalten in Veterinary research London : BioMed Central, 1993 42(2011), 1 vom: 02. Sept. (DE-627)312853653 (DE-600)2012391-7 1297-9716 nnns volume:42 year:2011 number:1 day:02 month:09 https://dx.doi.org/10.1186/1297-9716-42-98 kostenfrei Volltext GBV_USEFLAG_A SYSFLAG_A GBV_SPRINGER GBV_ILN_11 GBV_ILN_20 GBV_ILN_22 GBV_ILN_24 GBV_ILN_31 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_70 GBV_ILN_73 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_213 GBV_ILN_230 GBV_ILN_252 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_2003 GBV_ILN_2014 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 46.00 ASE AR 42 2011 1 02 09
language	English
source	Enthalten in Veterinary research 42(2011), 1 vom: 02. Sept. volume:42 year:2011 number:1 day:02 month:09
sourceStr	Enthalten in Veterinary research 42(2011), 1 vom: 02. Sept. volume:42 year:2011 number:1 day:02 month:09
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topic_facet	Antimicrobial Activity Lysozyme Acne Antimicrobial Peptide Paneth Cell
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container_title	Veterinary research
authorswithroles_txt_mv	Bruhn, Oliver @@aut@@ Grötzinger, Joachim @@aut@@ Cascorbi, Ingolf @@aut@@ Jung, Sascha @@aut@@
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author	Bruhn, Oliver
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topic_title	630 640 ASE 46.00 bkl Antimicrobial peptides and proteins of the horse - insights into a well-armed organism Antimicrobial Activity (dpeaa)DE-He213 Lysozyme (dpeaa)DE-He213 Acne (dpeaa)DE-He213 Antimicrobial Peptide (dpeaa)DE-He213 Paneth Cell (dpeaa)DE-He213
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title	Antimicrobial peptides and proteins of the horse - insights into a well-armed organism
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title_sort	antimicrobial peptides and proteins of the horse - insights into a well-armed organism
title_auth	Antimicrobial peptides and proteins of the horse - insights into a well-armed organism
abstract	Abstract Antimicrobial peptides play a pivotal role as key effectors of the innate immune system in plants and animals and act as endogenous antibiotics. The molecules exhibit an antimicrobial activity against bacteria, viruses, and eukaryotic pathogens with different specificities and potencies depending on the structure and amino-acid composition of the peptides. Several antimicrobial peptides were comprehensively investigated in the last three decades and some molecules with remarkable antimicrobial properties have reached the third phase of clinical studies. Next to the peptides themselves, numerous organisms were examined and analyzed regarding their repertoire of antimicrobial peptides revealing a huge number of candidates with potencies and properties for future medical applications. One of these organisms is the horse, which possesses numerous peptides that are interesting candidates for therapeutical applications in veterinary medicine. Here we summarize investigations and knowledge on equine antimicrobial peptides, point to interesting candidates, and discuss prospects for therapeutical applications.
abstractGer	Abstract Antimicrobial peptides play a pivotal role as key effectors of the innate immune system in plants and animals and act as endogenous antibiotics. The molecules exhibit an antimicrobial activity against bacteria, viruses, and eukaryotic pathogens with different specificities and potencies depending on the structure and amino-acid composition of the peptides. Several antimicrobial peptides were comprehensively investigated in the last three decades and some molecules with remarkable antimicrobial properties have reached the third phase of clinical studies. Next to the peptides themselves, numerous organisms were examined and analyzed regarding their repertoire of antimicrobial peptides revealing a huge number of candidates with potencies and properties for future medical applications. One of these organisms is the horse, which possesses numerous peptides that are interesting candidates for therapeutical applications in veterinary medicine. Here we summarize investigations and knowledge on equine antimicrobial peptides, point to interesting candidates, and discuss prospects for therapeutical applications.
abstract_unstemmed	Abstract Antimicrobial peptides play a pivotal role as key effectors of the innate immune system in plants and animals and act as endogenous antibiotics. The molecules exhibit an antimicrobial activity against bacteria, viruses, and eukaryotic pathogens with different specificities and potencies depending on the structure and amino-acid composition of the peptides. Several antimicrobial peptides were comprehensively investigated in the last three decades and some molecules with remarkable antimicrobial properties have reached the third phase of clinical studies. Next to the peptides themselves, numerous organisms were examined and analyzed regarding their repertoire of antimicrobial peptides revealing a huge number of candidates with potencies and properties for future medical applications. One of these organisms is the horse, which possesses numerous peptides that are interesting candidates for therapeutical applications in veterinary medicine. Here we summarize investigations and knowledge on equine antimicrobial peptides, point to interesting candidates, and discuss prospects for therapeutical applications.
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title_short	Antimicrobial peptides and proteins of the horse - insights into a well-armed organism
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