Ginsenoside Rb1 increases synaptophysin and microtubule-associated protein 2 mRNA expression in primary cultures of rat hippocampal neurons
Abstract Ginsenoside Rb1 has been determined to exert diverse neuromodulatory effects including a stimulatory effect on synaptic formation. Synaptophysin and microtubule-associated protein 2 (MAP2) are synaptic proteins which play vital roles in neurotransmission regulation and synaptic structural s...
Ausführliche Beschreibung
Gespeichert in:
| Autor*in: |
Nam, Kyong Nyon [verfasserIn] Jung, Woo-Sang [verfasserIn] Park, Ji-Ho [verfasserIn] Lee, Eunjoo H. [verfasserIn] |
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| Format: |
E-Artikel |
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| Sprache: |
Englisch |
| Erschienen: |
2013 |
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| Schlagwörter: |
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| Übergeordnetes Werk: |
Enthalten in: Oriental pharmacy and experimental medicine - Dordrecht : Springer, 2011, 13(2013), 3 vom: 16. Jan., Seite 231-234 |
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| Übergeordnetes Werk: |
volume:13 ; year:2013 ; number:3 ; day:16 ; month:01 ; pages:231-234 |
| Links: |
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| DOI / URN: |
10.1007/s13596-012-0101-3 |
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| Katalog-ID: |
SPR031904165 |
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| 245 | 1 | 0 | |a Ginsenoside Rb1 increases synaptophysin and microtubule-associated protein 2 mRNA expression in primary cultures of rat hippocampal neurons |
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| 520 | |a Abstract Ginsenoside Rb1 has been determined to exert diverse neuromodulatory effects including a stimulatory effect on synaptic formation. Synaptophysin and microtubule-associated protein 2 (MAP2) are synaptic proteins which play vital roles in neurotransmission regulation and synaptic structural stability. The present data revealed that ginsenoside Rb1 enhanced mRNA expression of synaptic markers, synaptophysin and MAP2, in primary cultured rat hippocampal neurons. Our results newly add synaptophysin and MAP2 to the list of genes of which mRNA expression is modulated by ginsenosides. Our finding contributes further understanding of medical usefulness of ginsenoside Rb1 targeting hippocampal network alteration which is commonly observed in aging and neurodegenerative disorders. | ||
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| 700 | 1 | |a Park, Ji-Ho |e verfasserin |4 aut | |
| 700 | 1 | |a Lee, Eunjoo H. |e verfasserin |4 aut | |
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10.1007/s13596-012-0101-3 doi (DE-627)SPR031904165 (SPR)s13596-012-0101-3-e DE-627 ger DE-627 rakwb eng 610 ASE Nam, Kyong Nyon verfasserin aut Ginsenoside Rb1 increases synaptophysin and microtubule-associated protein 2 mRNA expression in primary cultures of rat hippocampal neurons 2013 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Abstract Ginsenoside Rb1 has been determined to exert diverse neuromodulatory effects including a stimulatory effect on synaptic formation. Synaptophysin and microtubule-associated protein 2 (MAP2) are synaptic proteins which play vital roles in neurotransmission regulation and synaptic structural stability. The present data revealed that ginsenoside Rb1 enhanced mRNA expression of synaptic markers, synaptophysin and MAP2, in primary cultured rat hippocampal neurons. Our results newly add synaptophysin and MAP2 to the list of genes of which mRNA expression is modulated by ginsenosides. Our finding contributes further understanding of medical usefulness of ginsenoside Rb1 targeting hippocampal network alteration which is commonly observed in aging and neurodegenerative disorders. Ginsenoside Rb1 (dpeaa)DE-He213 Hippocampal neurons (dpeaa)DE-He213 Microtubule-associated protein 2 (dpeaa)DE-He213 Real-time PCR (dpeaa)DE-He213 Synaptophysin (dpeaa)DE-He213 Jung, Woo-Sang verfasserin aut Park, Ji-Ho verfasserin aut Lee, Eunjoo H. verfasserin aut Enthalten in Oriental pharmacy and experimental medicine Dordrecht : Springer, 2011 13(2013), 3 vom: 16. Jan., Seite 231-234 (DE-627)689127340 (DE-600)2655275-9 2211-1069 nnns volume:13 year:2013 number:3 day:16 month:01 pages:231-234 https://dx.doi.org/10.1007/s13596-012-0101-3 lizenzpflichtig Volltext GBV_USEFLAG_A SYSFLAG_A GBV_SPRINGER SSG-OLC-PHA SSG-OPC-PHA SSG-OPC-ASE GBV_ILN_11 GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_32 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_70 GBV_ILN_73 GBV_ILN_74 GBV_ILN_90 GBV_ILN_95 GBV_ILN_100 GBV_ILN_101 GBV_ILN_105 GBV_ILN_110 GBV_ILN_120 GBV_ILN_138 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_171 GBV_ILN_187 GBV_ILN_213 GBV_ILN_224 GBV_ILN_230 GBV_ILN_250 GBV_ILN_281 GBV_ILN_285 GBV_ILN_293 GBV_ILN_370 GBV_ILN_602 GBV_ILN_636 GBV_ILN_702 GBV_ILN_2001 GBV_ILN_2003 GBV_ILN_2004 GBV_ILN_2005 GBV_ILN_2006 GBV_ILN_2007 GBV_ILN_2008 GBV_ILN_2009 GBV_ILN_2010 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2015 GBV_ILN_2020 GBV_ILN_2021 GBV_ILN_2025 GBV_ILN_2026 GBV_ILN_2027 GBV_ILN_2031 GBV_ILN_2034 GBV_ILN_2037 GBV_ILN_2038 GBV_ILN_2039 GBV_ILN_2044 GBV_ILN_2048 GBV_ILN_2049 GBV_ILN_2050 GBV_ILN_2055 GBV_ILN_2057 GBV_ILN_2059 GBV_ILN_2061 GBV_ILN_2064 GBV_ILN_2065 GBV_ILN_2068 GBV_ILN_2070 GBV_ILN_2086 GBV_ILN_2088 GBV_ILN_2093 GBV_ILN_2106 GBV_ILN_2107 GBV_ILN_2108 GBV_ILN_2110 GBV_ILN_2111 GBV_ILN_2112 GBV_ILN_2113 GBV_ILN_2116 GBV_ILN_2118 GBV_ILN_2119 GBV_ILN_2122 GBV_ILN_2129 GBV_ILN_2143 GBV_ILN_2144 GBV_ILN_2147 GBV_ILN_2148 GBV_ILN_2152 GBV_ILN_2153 GBV_ILN_2188 GBV_ILN_2232 GBV_ILN_2336 GBV_ILN_2446 GBV_ILN_2470 GBV_ILN_2472 GBV_ILN_2507 GBV_ILN_2522 GBV_ILN_2548 GBV_ILN_4035 GBV_ILN_4037 GBV_ILN_4046 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4242 GBV_ILN_4246 GBV_ILN_4249 GBV_ILN_4251 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4326 GBV_ILN_4333 GBV_ILN_4334 GBV_ILN_4335 GBV_ILN_4336 GBV_ILN_4338 GBV_ILN_4393 GBV_ILN_4700 AR 13 2013 3 16 01 231-234 |
| spelling |
10.1007/s13596-012-0101-3 doi (DE-627)SPR031904165 (SPR)s13596-012-0101-3-e DE-627 ger DE-627 rakwb eng 610 ASE Nam, Kyong Nyon verfasserin aut Ginsenoside Rb1 increases synaptophysin and microtubule-associated protein 2 mRNA expression in primary cultures of rat hippocampal neurons 2013 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Abstract Ginsenoside Rb1 has been determined to exert diverse neuromodulatory effects including a stimulatory effect on synaptic formation. Synaptophysin and microtubule-associated protein 2 (MAP2) are synaptic proteins which play vital roles in neurotransmission regulation and synaptic structural stability. The present data revealed that ginsenoside Rb1 enhanced mRNA expression of synaptic markers, synaptophysin and MAP2, in primary cultured rat hippocampal neurons. Our results newly add synaptophysin and MAP2 to the list of genes of which mRNA expression is modulated by ginsenosides. Our finding contributes further understanding of medical usefulness of ginsenoside Rb1 targeting hippocampal network alteration which is commonly observed in aging and neurodegenerative disorders. Ginsenoside Rb1 (dpeaa)DE-He213 Hippocampal neurons (dpeaa)DE-He213 Microtubule-associated protein 2 (dpeaa)DE-He213 Real-time PCR (dpeaa)DE-He213 Synaptophysin (dpeaa)DE-He213 Jung, Woo-Sang verfasserin aut Park, Ji-Ho verfasserin aut Lee, Eunjoo H. verfasserin aut Enthalten in Oriental pharmacy and experimental medicine Dordrecht : Springer, 2011 13(2013), 3 vom: 16. Jan., Seite 231-234 (DE-627)689127340 (DE-600)2655275-9 2211-1069 nnns volume:13 year:2013 number:3 day:16 month:01 pages:231-234 https://dx.doi.org/10.1007/s13596-012-0101-3 lizenzpflichtig Volltext GBV_USEFLAG_A SYSFLAG_A GBV_SPRINGER SSG-OLC-PHA SSG-OPC-PHA SSG-OPC-ASE GBV_ILN_11 GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_32 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_70 GBV_ILN_73 GBV_ILN_74 GBV_ILN_90 GBV_ILN_95 GBV_ILN_100 GBV_ILN_101 GBV_ILN_105 GBV_ILN_110 GBV_ILN_120 GBV_ILN_138 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_171 GBV_ILN_187 GBV_ILN_213 GBV_ILN_224 GBV_ILN_230 GBV_ILN_250 GBV_ILN_281 GBV_ILN_285 GBV_ILN_293 GBV_ILN_370 GBV_ILN_602 GBV_ILN_636 GBV_ILN_702 GBV_ILN_2001 GBV_ILN_2003 GBV_ILN_2004 GBV_ILN_2005 GBV_ILN_2006 GBV_ILN_2007 GBV_ILN_2008 GBV_ILN_2009 GBV_ILN_2010 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2015 GBV_ILN_2020 GBV_ILN_2021 GBV_ILN_2025 GBV_ILN_2026 GBV_ILN_2027 GBV_ILN_2031 GBV_ILN_2034 GBV_ILN_2037 GBV_ILN_2038 GBV_ILN_2039 GBV_ILN_2044 GBV_ILN_2048 GBV_ILN_2049 GBV_ILN_2050 GBV_ILN_2055 GBV_ILN_2057 GBV_ILN_2059 GBV_ILN_2061 GBV_ILN_2064 GBV_ILN_2065 GBV_ILN_2068 GBV_ILN_2070 GBV_ILN_2086 GBV_ILN_2088 GBV_ILN_2093 GBV_ILN_2106 GBV_ILN_2107 GBV_ILN_2108 GBV_ILN_2110 GBV_ILN_2111 GBV_ILN_2112 GBV_ILN_2113 GBV_ILN_2116 GBV_ILN_2118 GBV_ILN_2119 GBV_ILN_2122 GBV_ILN_2129 GBV_ILN_2143 GBV_ILN_2144 GBV_ILN_2147 GBV_ILN_2148 GBV_ILN_2152 GBV_ILN_2153 GBV_ILN_2188 GBV_ILN_2232 GBV_ILN_2336 GBV_ILN_2446 GBV_ILN_2470 GBV_ILN_2472 GBV_ILN_2507 GBV_ILN_2522 GBV_ILN_2548 GBV_ILN_4035 GBV_ILN_4037 GBV_ILN_4046 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4242 GBV_ILN_4246 GBV_ILN_4249 GBV_ILN_4251 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4326 GBV_ILN_4333 GBV_ILN_4334 GBV_ILN_4335 GBV_ILN_4336 GBV_ILN_4338 GBV_ILN_4393 GBV_ILN_4700 AR 13 2013 3 16 01 231-234 |
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10.1007/s13596-012-0101-3 doi (DE-627)SPR031904165 (SPR)s13596-012-0101-3-e DE-627 ger DE-627 rakwb eng 610 ASE Nam, Kyong Nyon verfasserin aut Ginsenoside Rb1 increases synaptophysin and microtubule-associated protein 2 mRNA expression in primary cultures of rat hippocampal neurons 2013 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Abstract Ginsenoside Rb1 has been determined to exert diverse neuromodulatory effects including a stimulatory effect on synaptic formation. Synaptophysin and microtubule-associated protein 2 (MAP2) are synaptic proteins which play vital roles in neurotransmission regulation and synaptic structural stability. The present data revealed that ginsenoside Rb1 enhanced mRNA expression of synaptic markers, synaptophysin and MAP2, in primary cultured rat hippocampal neurons. Our results newly add synaptophysin and MAP2 to the list of genes of which mRNA expression is modulated by ginsenosides. Our finding contributes further understanding of medical usefulness of ginsenoside Rb1 targeting hippocampal network alteration which is commonly observed in aging and neurodegenerative disorders. Ginsenoside Rb1 (dpeaa)DE-He213 Hippocampal neurons (dpeaa)DE-He213 Microtubule-associated protein 2 (dpeaa)DE-He213 Real-time PCR (dpeaa)DE-He213 Synaptophysin (dpeaa)DE-He213 Jung, Woo-Sang verfasserin aut Park, Ji-Ho verfasserin aut Lee, Eunjoo H. verfasserin aut Enthalten in Oriental pharmacy and experimental medicine Dordrecht : Springer, 2011 13(2013), 3 vom: 16. Jan., Seite 231-234 (DE-627)689127340 (DE-600)2655275-9 2211-1069 nnns volume:13 year:2013 number:3 day:16 month:01 pages:231-234 https://dx.doi.org/10.1007/s13596-012-0101-3 lizenzpflichtig Volltext GBV_USEFLAG_A SYSFLAG_A GBV_SPRINGER SSG-OLC-PHA SSG-OPC-PHA SSG-OPC-ASE GBV_ILN_11 GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_32 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_70 GBV_ILN_73 GBV_ILN_74 GBV_ILN_90 GBV_ILN_95 GBV_ILN_100 GBV_ILN_101 GBV_ILN_105 GBV_ILN_110 GBV_ILN_120 GBV_ILN_138 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_171 GBV_ILN_187 GBV_ILN_213 GBV_ILN_224 GBV_ILN_230 GBV_ILN_250 GBV_ILN_281 GBV_ILN_285 GBV_ILN_293 GBV_ILN_370 GBV_ILN_602 GBV_ILN_636 GBV_ILN_702 GBV_ILN_2001 GBV_ILN_2003 GBV_ILN_2004 GBV_ILN_2005 GBV_ILN_2006 GBV_ILN_2007 GBV_ILN_2008 GBV_ILN_2009 GBV_ILN_2010 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2015 GBV_ILN_2020 GBV_ILN_2021 GBV_ILN_2025 GBV_ILN_2026 GBV_ILN_2027 GBV_ILN_2031 GBV_ILN_2034 GBV_ILN_2037 GBV_ILN_2038 GBV_ILN_2039 GBV_ILN_2044 GBV_ILN_2048 GBV_ILN_2049 GBV_ILN_2050 GBV_ILN_2055 GBV_ILN_2057 GBV_ILN_2059 GBV_ILN_2061 GBV_ILN_2064 GBV_ILN_2065 GBV_ILN_2068 GBV_ILN_2070 GBV_ILN_2086 GBV_ILN_2088 GBV_ILN_2093 GBV_ILN_2106 GBV_ILN_2107 GBV_ILN_2108 GBV_ILN_2110 GBV_ILN_2111 GBV_ILN_2112 GBV_ILN_2113 GBV_ILN_2116 GBV_ILN_2118 GBV_ILN_2119 GBV_ILN_2122 GBV_ILN_2129 GBV_ILN_2143 GBV_ILN_2144 GBV_ILN_2147 GBV_ILN_2148 GBV_ILN_2152 GBV_ILN_2153 GBV_ILN_2188 GBV_ILN_2232 GBV_ILN_2336 GBV_ILN_2446 GBV_ILN_2470 GBV_ILN_2472 GBV_ILN_2507 GBV_ILN_2522 GBV_ILN_2548 GBV_ILN_4035 GBV_ILN_4037 GBV_ILN_4046 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4242 GBV_ILN_4246 GBV_ILN_4249 GBV_ILN_4251 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4326 GBV_ILN_4333 GBV_ILN_4334 GBV_ILN_4335 GBV_ILN_4336 GBV_ILN_4338 GBV_ILN_4393 GBV_ILN_4700 AR 13 2013 3 16 01 231-234 |
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10.1007/s13596-012-0101-3 doi (DE-627)SPR031904165 (SPR)s13596-012-0101-3-e DE-627 ger DE-627 rakwb eng 610 ASE Nam, Kyong Nyon verfasserin aut Ginsenoside Rb1 increases synaptophysin and microtubule-associated protein 2 mRNA expression in primary cultures of rat hippocampal neurons 2013 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Abstract Ginsenoside Rb1 has been determined to exert diverse neuromodulatory effects including a stimulatory effect on synaptic formation. Synaptophysin and microtubule-associated protein 2 (MAP2) are synaptic proteins which play vital roles in neurotransmission regulation and synaptic structural stability. The present data revealed that ginsenoside Rb1 enhanced mRNA expression of synaptic markers, synaptophysin and MAP2, in primary cultured rat hippocampal neurons. Our results newly add synaptophysin and MAP2 to the list of genes of which mRNA expression is modulated by ginsenosides. Our finding contributes further understanding of medical usefulness of ginsenoside Rb1 targeting hippocampal network alteration which is commonly observed in aging and neurodegenerative disorders. Ginsenoside Rb1 (dpeaa)DE-He213 Hippocampal neurons (dpeaa)DE-He213 Microtubule-associated protein 2 (dpeaa)DE-He213 Real-time PCR (dpeaa)DE-He213 Synaptophysin (dpeaa)DE-He213 Jung, Woo-Sang verfasserin aut Park, Ji-Ho verfasserin aut Lee, Eunjoo H. verfasserin aut Enthalten in Oriental pharmacy and experimental medicine Dordrecht : Springer, 2011 13(2013), 3 vom: 16. Jan., Seite 231-234 (DE-627)689127340 (DE-600)2655275-9 2211-1069 nnns volume:13 year:2013 number:3 day:16 month:01 pages:231-234 https://dx.doi.org/10.1007/s13596-012-0101-3 lizenzpflichtig Volltext GBV_USEFLAG_A SYSFLAG_A GBV_SPRINGER SSG-OLC-PHA SSG-OPC-PHA SSG-OPC-ASE GBV_ILN_11 GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_32 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_70 GBV_ILN_73 GBV_ILN_74 GBV_ILN_90 GBV_ILN_95 GBV_ILN_100 GBV_ILN_101 GBV_ILN_105 GBV_ILN_110 GBV_ILN_120 GBV_ILN_138 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_171 GBV_ILN_187 GBV_ILN_213 GBV_ILN_224 GBV_ILN_230 GBV_ILN_250 GBV_ILN_281 GBV_ILN_285 GBV_ILN_293 GBV_ILN_370 GBV_ILN_602 GBV_ILN_636 GBV_ILN_702 GBV_ILN_2001 GBV_ILN_2003 GBV_ILN_2004 GBV_ILN_2005 GBV_ILN_2006 GBV_ILN_2007 GBV_ILN_2008 GBV_ILN_2009 GBV_ILN_2010 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2015 GBV_ILN_2020 GBV_ILN_2021 GBV_ILN_2025 GBV_ILN_2026 GBV_ILN_2027 GBV_ILN_2031 GBV_ILN_2034 GBV_ILN_2037 GBV_ILN_2038 GBV_ILN_2039 GBV_ILN_2044 GBV_ILN_2048 GBV_ILN_2049 GBV_ILN_2050 GBV_ILN_2055 GBV_ILN_2057 GBV_ILN_2059 GBV_ILN_2061 GBV_ILN_2064 GBV_ILN_2065 GBV_ILN_2068 GBV_ILN_2070 GBV_ILN_2086 GBV_ILN_2088 GBV_ILN_2093 GBV_ILN_2106 GBV_ILN_2107 GBV_ILN_2108 GBV_ILN_2110 GBV_ILN_2111 GBV_ILN_2112 GBV_ILN_2113 GBV_ILN_2116 GBV_ILN_2118 GBV_ILN_2119 GBV_ILN_2122 GBV_ILN_2129 GBV_ILN_2143 GBV_ILN_2144 GBV_ILN_2147 GBV_ILN_2148 GBV_ILN_2152 GBV_ILN_2153 GBV_ILN_2188 GBV_ILN_2232 GBV_ILN_2336 GBV_ILN_2446 GBV_ILN_2470 GBV_ILN_2472 GBV_ILN_2507 GBV_ILN_2522 GBV_ILN_2548 GBV_ILN_4035 GBV_ILN_4037 GBV_ILN_4046 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4242 GBV_ILN_4246 GBV_ILN_4249 GBV_ILN_4251 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4326 GBV_ILN_4333 GBV_ILN_4334 GBV_ILN_4335 GBV_ILN_4336 GBV_ILN_4338 GBV_ILN_4393 GBV_ILN_4700 AR 13 2013 3 16 01 231-234 |
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Enthalten in Oriental pharmacy and experimental medicine 13(2013), 3 vom: 16. Jan., Seite 231-234 volume:13 year:2013 number:3 day:16 month:01 pages:231-234 |
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Ginsenoside Rb1 Hippocampal neurons Microtubule-associated protein 2 Real-time PCR Synaptophysin |
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Oriental pharmacy and experimental medicine |
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Nam, Kyong Nyon @@aut@@ Jung, Woo-Sang @@aut@@ Park, Ji-Ho @@aut@@ Lee, Eunjoo H. @@aut@@ |
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2013-01-16T00:00:00Z |
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Nam, Kyong Nyon |
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Nam, Kyong Nyon ddc 610 misc Ginsenoside Rb1 misc Hippocampal neurons misc Microtubule-associated protein 2 misc Real-time PCR misc Synaptophysin Ginsenoside Rb1 increases synaptophysin and microtubule-associated protein 2 mRNA expression in primary cultures of rat hippocampal neurons |
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610 ASE Ginsenoside Rb1 increases synaptophysin and microtubule-associated protein 2 mRNA expression in primary cultures of rat hippocampal neurons Ginsenoside Rb1 (dpeaa)DE-He213 Hippocampal neurons (dpeaa)DE-He213 Microtubule-associated protein 2 (dpeaa)DE-He213 Real-time PCR (dpeaa)DE-He213 Synaptophysin (dpeaa)DE-He213 |
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ddc 610 misc Ginsenoside Rb1 misc Hippocampal neurons misc Microtubule-associated protein 2 misc Real-time PCR misc Synaptophysin |
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ddc 610 misc Ginsenoside Rb1 misc Hippocampal neurons misc Microtubule-associated protein 2 misc Real-time PCR misc Synaptophysin |
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ddc 610 misc Ginsenoside Rb1 misc Hippocampal neurons misc Microtubule-associated protein 2 misc Real-time PCR misc Synaptophysin |
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Ginsenoside Rb1 increases synaptophysin and microtubule-associated protein 2 mRNA expression in primary cultures of rat hippocampal neurons |
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Ginsenoside Rb1 increases synaptophysin and microtubule-associated protein 2 mRNA expression in primary cultures of rat hippocampal neurons |
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Nam, Kyong Nyon |
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Oriental pharmacy and experimental medicine |
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Nam, Kyong Nyon Jung, Woo-Sang Park, Ji-Ho Lee, Eunjoo H. |
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Nam, Kyong Nyon |
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ginsenoside rb1 increases synaptophysin and microtubule-associated protein 2 mrna expression in primary cultures of rat hippocampal neurons |
| title_auth |
Ginsenoside Rb1 increases synaptophysin and microtubule-associated protein 2 mRNA expression in primary cultures of rat hippocampal neurons |
| abstract |
Abstract Ginsenoside Rb1 has been determined to exert diverse neuromodulatory effects including a stimulatory effect on synaptic formation. Synaptophysin and microtubule-associated protein 2 (MAP2) are synaptic proteins which play vital roles in neurotransmission regulation and synaptic structural stability. The present data revealed that ginsenoside Rb1 enhanced mRNA expression of synaptic markers, synaptophysin and MAP2, in primary cultured rat hippocampal neurons. Our results newly add synaptophysin and MAP2 to the list of genes of which mRNA expression is modulated by ginsenosides. Our finding contributes further understanding of medical usefulness of ginsenoside Rb1 targeting hippocampal network alteration which is commonly observed in aging and neurodegenerative disorders. |
| abstractGer |
Abstract Ginsenoside Rb1 has been determined to exert diverse neuromodulatory effects including a stimulatory effect on synaptic formation. Synaptophysin and microtubule-associated protein 2 (MAP2) are synaptic proteins which play vital roles in neurotransmission regulation and synaptic structural stability. The present data revealed that ginsenoside Rb1 enhanced mRNA expression of synaptic markers, synaptophysin and MAP2, in primary cultured rat hippocampal neurons. Our results newly add synaptophysin and MAP2 to the list of genes of which mRNA expression is modulated by ginsenosides. Our finding contributes further understanding of medical usefulness of ginsenoside Rb1 targeting hippocampal network alteration which is commonly observed in aging and neurodegenerative disorders. |
| abstract_unstemmed |
Abstract Ginsenoside Rb1 has been determined to exert diverse neuromodulatory effects including a stimulatory effect on synaptic formation. Synaptophysin and microtubule-associated protein 2 (MAP2) are synaptic proteins which play vital roles in neurotransmission regulation and synaptic structural stability. The present data revealed that ginsenoside Rb1 enhanced mRNA expression of synaptic markers, synaptophysin and MAP2, in primary cultured rat hippocampal neurons. Our results newly add synaptophysin and MAP2 to the list of genes of which mRNA expression is modulated by ginsenosides. Our finding contributes further understanding of medical usefulness of ginsenoside Rb1 targeting hippocampal network alteration which is commonly observed in aging and neurodegenerative disorders. |
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Ginsenoside Rb1 increases synaptophysin and microtubule-associated protein 2 mRNA expression in primary cultures of rat hippocampal neurons |
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https://dx.doi.org/10.1007/s13596-012-0101-3 |
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Jung, Woo-Sang Park, Ji-Ho Lee, Eunjoo H. |
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| doi_str |
10.1007/s13596-012-0101-3 |
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2024-07-04T01:45:56.405Z |
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