Earlobe arterialized capillary blood gas analysis in the intensive care unit: a pilot study
Background Earlobe arterialized capillary blood gas analysis can be used to estimate arterial gas content and may be suitable for diagnosis and management of critically ill patients. However, its utility and applicability in the ICU setting remains unexplored. Methods A prospective observational val...
Ausführliche Beschreibung
Gespeichert in:
| Autor*in: |
Vaquer, Sergi [verfasserIn] Masip, Jordi [verfasserIn] Gili, Gisela [verfasserIn] Gomà, Gemma [verfasserIn] Oliva, Joan Carles [verfasserIn] Frechette, Alexandre [verfasserIn] Evetts, Simon [verfasserIn] Russomano, Thais [verfasserIn] Artigas, Antonio [verfasserIn] |
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E-Artikel |
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| Sprache: |
Englisch |
| Erschienen: |
2014 |
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| Übergeordnetes Werk: |
Enthalten in: Annals of intensive care - Heidelberg : Springer, 2011, 4(2014), 1 vom: 14. Apr. |
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| Übergeordnetes Werk: |
volume:4 ; year:2014 ; number:1 ; day:14 ; month:04 |
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| DOI / URN: |
10.1186/2110-5820-4-11 |
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| Katalog-ID: |
SPR031927505 |
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| 520 | |a Background Earlobe arterialized capillary blood gas analysis can be used to estimate arterial gas content and may be suitable for diagnosis and management of critically ill patients. However, its utility and applicability in the ICU setting remains unexplored. Methods A prospective observational validation study was designed to evaluate this technique in a cohort of mechanically ventilated adult critically ill patients admitted to a polyvalent ICU. Precision and agreement between capillary gas measures and arterial references was examined. Acute Respiratory Distress Syndrome (ARDS) diagnosis capabilities with the proposed technique were also evaluated. Finally, factors associated with sampling failure were explored. Results Fifty-five patients were included into this study. Precision of capillary samples was high (Coefficient of Variation $ PO_{2} $ = 9.8%, $ PCO_{2} $ = 7.7%, pH = 0.3%). $ PO_{2} $ measures showed insufficient agreement levels (Concordance Correlation Coefficient = 0.45; bias = 12 mmHg; percentage of error = 19.3%), whereas better agreement was observed for $ PCO_{2} $ and pH (Concordance Correlation Coefficient = 0.94 and 0.93 respectively; depreciable bias; percentage of error 11.4% and 0.5% respectively). The sensitivity and specificity for diagnosing ARDS were 100% and 92.3% using capillary gasometric measures. Sampling was unsuccessful in 43.6% of cases due to insufficient blood flow. Age > 65 years was independently associated with failure (odds ratio = 1.6), however hemodynamic failure and norepinephrine treatment were also influencing factors. Conclusions Earlobe capillary blood gas analysis is precise and can be useful for detecting extreme gasometrical values. Diagnosis of ARDS can be done accurately using capillary measurements. Although this technique may be insufficient for precise management of patients in the ICU, it has the potential for important benefits in the acute phase of various critical conditions and in other critical care arenas, such as in emergency medicine, advanced medical transport and pre-hospital critical care. | ||
| 650 | 4 | |a Acute respiratory failure |7 (dpeaa)DE-He213 | |
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| 650 | 4 | |a Intensive care medicine |7 (dpeaa)DE-He213 | |
| 650 | 4 | |a Mechanical ventilation |7 (dpeaa)DE-He213 | |
| 700 | 1 | |a Masip, Jordi |e verfasserin |4 aut | |
| 700 | 1 | |a Gili, Gisela |e verfasserin |4 aut | |
| 700 | 1 | |a Gomà, Gemma |e verfasserin |4 aut | |
| 700 | 1 | |a Oliva, Joan Carles |e verfasserin |4 aut | |
| 700 | 1 | |a Frechette, Alexandre |e verfasserin |4 aut | |
| 700 | 1 | |a Evetts, Simon |e verfasserin |4 aut | |
| 700 | 1 | |a Russomano, Thais |e verfasserin |4 aut | |
| 700 | 1 | |a Artigas, Antonio |e verfasserin |4 aut | |
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10.1186/2110-5820-4-11 doi (DE-627)SPR031927505 (SPR)2110-5820-4-11-e DE-627 ger DE-627 rakwb eng 610 ASE Vaquer, Sergi verfasserin aut Earlobe arterialized capillary blood gas analysis in the intensive care unit: a pilot study 2014 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Background Earlobe arterialized capillary blood gas analysis can be used to estimate arterial gas content and may be suitable for diagnosis and management of critically ill patients. However, its utility and applicability in the ICU setting remains unexplored. Methods A prospective observational validation study was designed to evaluate this technique in a cohort of mechanically ventilated adult critically ill patients admitted to a polyvalent ICU. Precision and agreement between capillary gas measures and arterial references was examined. Acute Respiratory Distress Syndrome (ARDS) diagnosis capabilities with the proposed technique were also evaluated. Finally, factors associated with sampling failure were explored. Results Fifty-five patients were included into this study. Precision of capillary samples was high (Coefficient of Variation $ PO_{2} $ = 9.8%, $ PCO_{2} $ = 7.7%, pH = 0.3%). $ PO_{2} $ measures showed insufficient agreement levels (Concordance Correlation Coefficient = 0.45; bias = 12 mmHg; percentage of error = 19.3%), whereas better agreement was observed for $ PCO_{2} $ and pH (Concordance Correlation Coefficient = 0.94 and 0.93 respectively; depreciable bias; percentage of error 11.4% and 0.5% respectively). The sensitivity and specificity for diagnosing ARDS were 100% and 92.3% using capillary gasometric measures. Sampling was unsuccessful in 43.6% of cases due to insufficient blood flow. Age > 65 years was independently associated with failure (odds ratio = 1.6), however hemodynamic failure and norepinephrine treatment were also influencing factors. Conclusions Earlobe capillary blood gas analysis is precise and can be useful for detecting extreme gasometrical values. Diagnosis of ARDS can be done accurately using capillary measurements. Although this technique may be insufficient for precise management of patients in the ICU, it has the potential for important benefits in the acute phase of various critical conditions and in other critical care arenas, such as in emergency medicine, advanced medical transport and pre-hospital critical care. Acute respiratory failure (dpeaa)DE-He213 Arterialized (dpeaa)DE-He213 Capillary blood (dpeaa)DE-He213 Emergency medicine (dpeaa)DE-He213 Intensive care medicine (dpeaa)DE-He213 Mechanical ventilation (dpeaa)DE-He213 Masip, Jordi verfasserin aut Gili, Gisela verfasserin aut Gomà, Gemma verfasserin aut Oliva, Joan Carles verfasserin aut Frechette, Alexandre verfasserin aut Evetts, Simon verfasserin aut Russomano, Thais verfasserin aut Artigas, Antonio verfasserin aut Enthalten in Annals of intensive care Heidelberg : Springer, 2011 4(2014), 1 vom: 14. Apr. (DE-627)664260918 (DE-600)2617094-2 2110-5820 nnns volume:4 year:2014 number:1 day:14 month:04 https://dx.doi.org/10.1186/2110-5820-4-11 kostenfrei Volltext GBV_USEFLAG_A SYSFLAG_A GBV_SPRINGER SSG-OLC-PHA GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_2014 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 4 2014 1 14 04 |
| spelling |
10.1186/2110-5820-4-11 doi (DE-627)SPR031927505 (SPR)2110-5820-4-11-e DE-627 ger DE-627 rakwb eng 610 ASE Vaquer, Sergi verfasserin aut Earlobe arterialized capillary blood gas analysis in the intensive care unit: a pilot study 2014 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Background Earlobe arterialized capillary blood gas analysis can be used to estimate arterial gas content and may be suitable for diagnosis and management of critically ill patients. However, its utility and applicability in the ICU setting remains unexplored. Methods A prospective observational validation study was designed to evaluate this technique in a cohort of mechanically ventilated adult critically ill patients admitted to a polyvalent ICU. Precision and agreement between capillary gas measures and arterial references was examined. Acute Respiratory Distress Syndrome (ARDS) diagnosis capabilities with the proposed technique were also evaluated. Finally, factors associated with sampling failure were explored. Results Fifty-five patients were included into this study. Precision of capillary samples was high (Coefficient of Variation $ PO_{2} $ = 9.8%, $ PCO_{2} $ = 7.7%, pH = 0.3%). $ PO_{2} $ measures showed insufficient agreement levels (Concordance Correlation Coefficient = 0.45; bias = 12 mmHg; percentage of error = 19.3%), whereas better agreement was observed for $ PCO_{2} $ and pH (Concordance Correlation Coefficient = 0.94 and 0.93 respectively; depreciable bias; percentage of error 11.4% and 0.5% respectively). The sensitivity and specificity for diagnosing ARDS were 100% and 92.3% using capillary gasometric measures. Sampling was unsuccessful in 43.6% of cases due to insufficient blood flow. Age > 65 years was independently associated with failure (odds ratio = 1.6), however hemodynamic failure and norepinephrine treatment were also influencing factors. Conclusions Earlobe capillary blood gas analysis is precise and can be useful for detecting extreme gasometrical values. Diagnosis of ARDS can be done accurately using capillary measurements. Although this technique may be insufficient for precise management of patients in the ICU, it has the potential for important benefits in the acute phase of various critical conditions and in other critical care arenas, such as in emergency medicine, advanced medical transport and pre-hospital critical care. Acute respiratory failure (dpeaa)DE-He213 Arterialized (dpeaa)DE-He213 Capillary blood (dpeaa)DE-He213 Emergency medicine (dpeaa)DE-He213 Intensive care medicine (dpeaa)DE-He213 Mechanical ventilation (dpeaa)DE-He213 Masip, Jordi verfasserin aut Gili, Gisela verfasserin aut Gomà, Gemma verfasserin aut Oliva, Joan Carles verfasserin aut Frechette, Alexandre verfasserin aut Evetts, Simon verfasserin aut Russomano, Thais verfasserin aut Artigas, Antonio verfasserin aut Enthalten in Annals of intensive care Heidelberg : Springer, 2011 4(2014), 1 vom: 14. Apr. (DE-627)664260918 (DE-600)2617094-2 2110-5820 nnns volume:4 year:2014 number:1 day:14 month:04 https://dx.doi.org/10.1186/2110-5820-4-11 kostenfrei Volltext GBV_USEFLAG_A SYSFLAG_A GBV_SPRINGER SSG-OLC-PHA GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_2014 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 4 2014 1 14 04 |
| allfields_unstemmed |
10.1186/2110-5820-4-11 doi (DE-627)SPR031927505 (SPR)2110-5820-4-11-e DE-627 ger DE-627 rakwb eng 610 ASE Vaquer, Sergi verfasserin aut Earlobe arterialized capillary blood gas analysis in the intensive care unit: a pilot study 2014 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Background Earlobe arterialized capillary blood gas analysis can be used to estimate arterial gas content and may be suitable for diagnosis and management of critically ill patients. However, its utility and applicability in the ICU setting remains unexplored. Methods A prospective observational validation study was designed to evaluate this technique in a cohort of mechanically ventilated adult critically ill patients admitted to a polyvalent ICU. Precision and agreement between capillary gas measures and arterial references was examined. Acute Respiratory Distress Syndrome (ARDS) diagnosis capabilities with the proposed technique were also evaluated. Finally, factors associated with sampling failure were explored. Results Fifty-five patients were included into this study. Precision of capillary samples was high (Coefficient of Variation $ PO_{2} $ = 9.8%, $ PCO_{2} $ = 7.7%, pH = 0.3%). $ PO_{2} $ measures showed insufficient agreement levels (Concordance Correlation Coefficient = 0.45; bias = 12 mmHg; percentage of error = 19.3%), whereas better agreement was observed for $ PCO_{2} $ and pH (Concordance Correlation Coefficient = 0.94 and 0.93 respectively; depreciable bias; percentage of error 11.4% and 0.5% respectively). The sensitivity and specificity for diagnosing ARDS were 100% and 92.3% using capillary gasometric measures. Sampling was unsuccessful in 43.6% of cases due to insufficient blood flow. Age > 65 years was independently associated with failure (odds ratio = 1.6), however hemodynamic failure and norepinephrine treatment were also influencing factors. Conclusions Earlobe capillary blood gas analysis is precise and can be useful for detecting extreme gasometrical values. Diagnosis of ARDS can be done accurately using capillary measurements. Although this technique may be insufficient for precise management of patients in the ICU, it has the potential for important benefits in the acute phase of various critical conditions and in other critical care arenas, such as in emergency medicine, advanced medical transport and pre-hospital critical care. Acute respiratory failure (dpeaa)DE-He213 Arterialized (dpeaa)DE-He213 Capillary blood (dpeaa)DE-He213 Emergency medicine (dpeaa)DE-He213 Intensive care medicine (dpeaa)DE-He213 Mechanical ventilation (dpeaa)DE-He213 Masip, Jordi verfasserin aut Gili, Gisela verfasserin aut Gomà, Gemma verfasserin aut Oliva, Joan Carles verfasserin aut Frechette, Alexandre verfasserin aut Evetts, Simon verfasserin aut Russomano, Thais verfasserin aut Artigas, Antonio verfasserin aut Enthalten in Annals of intensive care Heidelberg : Springer, 2011 4(2014), 1 vom: 14. Apr. (DE-627)664260918 (DE-600)2617094-2 2110-5820 nnns volume:4 year:2014 number:1 day:14 month:04 https://dx.doi.org/10.1186/2110-5820-4-11 kostenfrei Volltext GBV_USEFLAG_A SYSFLAG_A GBV_SPRINGER SSG-OLC-PHA GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_2014 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 4 2014 1 14 04 |
| allfieldsGer |
10.1186/2110-5820-4-11 doi (DE-627)SPR031927505 (SPR)2110-5820-4-11-e DE-627 ger DE-627 rakwb eng 610 ASE Vaquer, Sergi verfasserin aut Earlobe arterialized capillary blood gas analysis in the intensive care unit: a pilot study 2014 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Background Earlobe arterialized capillary blood gas analysis can be used to estimate arterial gas content and may be suitable for diagnosis and management of critically ill patients. However, its utility and applicability in the ICU setting remains unexplored. Methods A prospective observational validation study was designed to evaluate this technique in a cohort of mechanically ventilated adult critically ill patients admitted to a polyvalent ICU. Precision and agreement between capillary gas measures and arterial references was examined. Acute Respiratory Distress Syndrome (ARDS) diagnosis capabilities with the proposed technique were also evaluated. Finally, factors associated with sampling failure were explored. Results Fifty-five patients were included into this study. Precision of capillary samples was high (Coefficient of Variation $ PO_{2} $ = 9.8%, $ PCO_{2} $ = 7.7%, pH = 0.3%). $ PO_{2} $ measures showed insufficient agreement levels (Concordance Correlation Coefficient = 0.45; bias = 12 mmHg; percentage of error = 19.3%), whereas better agreement was observed for $ PCO_{2} $ and pH (Concordance Correlation Coefficient = 0.94 and 0.93 respectively; depreciable bias; percentage of error 11.4% and 0.5% respectively). The sensitivity and specificity for diagnosing ARDS were 100% and 92.3% using capillary gasometric measures. Sampling was unsuccessful in 43.6% of cases due to insufficient blood flow. Age > 65 years was independently associated with failure (odds ratio = 1.6), however hemodynamic failure and norepinephrine treatment were also influencing factors. Conclusions Earlobe capillary blood gas analysis is precise and can be useful for detecting extreme gasometrical values. Diagnosis of ARDS can be done accurately using capillary measurements. Although this technique may be insufficient for precise management of patients in the ICU, it has the potential for important benefits in the acute phase of various critical conditions and in other critical care arenas, such as in emergency medicine, advanced medical transport and pre-hospital critical care. Acute respiratory failure (dpeaa)DE-He213 Arterialized (dpeaa)DE-He213 Capillary blood (dpeaa)DE-He213 Emergency medicine (dpeaa)DE-He213 Intensive care medicine (dpeaa)DE-He213 Mechanical ventilation (dpeaa)DE-He213 Masip, Jordi verfasserin aut Gili, Gisela verfasserin aut Gomà, Gemma verfasserin aut Oliva, Joan Carles verfasserin aut Frechette, Alexandre verfasserin aut Evetts, Simon verfasserin aut Russomano, Thais verfasserin aut Artigas, Antonio verfasserin aut Enthalten in Annals of intensive care Heidelberg : Springer, 2011 4(2014), 1 vom: 14. Apr. (DE-627)664260918 (DE-600)2617094-2 2110-5820 nnns volume:4 year:2014 number:1 day:14 month:04 https://dx.doi.org/10.1186/2110-5820-4-11 kostenfrei Volltext GBV_USEFLAG_A SYSFLAG_A GBV_SPRINGER SSG-OLC-PHA GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_2014 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 4 2014 1 14 04 |
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10.1186/2110-5820-4-11 doi (DE-627)SPR031927505 (SPR)2110-5820-4-11-e DE-627 ger DE-627 rakwb eng 610 ASE Vaquer, Sergi verfasserin aut Earlobe arterialized capillary blood gas analysis in the intensive care unit: a pilot study 2014 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Background Earlobe arterialized capillary blood gas analysis can be used to estimate arterial gas content and may be suitable for diagnosis and management of critically ill patients. However, its utility and applicability in the ICU setting remains unexplored. Methods A prospective observational validation study was designed to evaluate this technique in a cohort of mechanically ventilated adult critically ill patients admitted to a polyvalent ICU. Precision and agreement between capillary gas measures and arterial references was examined. Acute Respiratory Distress Syndrome (ARDS) diagnosis capabilities with the proposed technique were also evaluated. Finally, factors associated with sampling failure were explored. Results Fifty-five patients were included into this study. Precision of capillary samples was high (Coefficient of Variation $ PO_{2} $ = 9.8%, $ PCO_{2} $ = 7.7%, pH = 0.3%). $ PO_{2} $ measures showed insufficient agreement levels (Concordance Correlation Coefficient = 0.45; bias = 12 mmHg; percentage of error = 19.3%), whereas better agreement was observed for $ PCO_{2} $ and pH (Concordance Correlation Coefficient = 0.94 and 0.93 respectively; depreciable bias; percentage of error 11.4% and 0.5% respectively). The sensitivity and specificity for diagnosing ARDS were 100% and 92.3% using capillary gasometric measures. Sampling was unsuccessful in 43.6% of cases due to insufficient blood flow. Age > 65 years was independently associated with failure (odds ratio = 1.6), however hemodynamic failure and norepinephrine treatment were also influencing factors. Conclusions Earlobe capillary blood gas analysis is precise and can be useful for detecting extreme gasometrical values. Diagnosis of ARDS can be done accurately using capillary measurements. Although this technique may be insufficient for precise management of patients in the ICU, it has the potential for important benefits in the acute phase of various critical conditions and in other critical care arenas, such as in emergency medicine, advanced medical transport and pre-hospital critical care. Acute respiratory failure (dpeaa)DE-He213 Arterialized (dpeaa)DE-He213 Capillary blood (dpeaa)DE-He213 Emergency medicine (dpeaa)DE-He213 Intensive care medicine (dpeaa)DE-He213 Mechanical ventilation (dpeaa)DE-He213 Masip, Jordi verfasserin aut Gili, Gisela verfasserin aut Gomà, Gemma verfasserin aut Oliva, Joan Carles verfasserin aut Frechette, Alexandre verfasserin aut Evetts, Simon verfasserin aut Russomano, Thais verfasserin aut Artigas, Antonio verfasserin aut Enthalten in Annals of intensive care Heidelberg : Springer, 2011 4(2014), 1 vom: 14. Apr. (DE-627)664260918 (DE-600)2617094-2 2110-5820 nnns volume:4 year:2014 number:1 day:14 month:04 https://dx.doi.org/10.1186/2110-5820-4-11 kostenfrei Volltext GBV_USEFLAG_A SYSFLAG_A GBV_SPRINGER SSG-OLC-PHA GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_2014 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 4 2014 1 14 04 |
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Earlobe arterialized capillary blood gas analysis in the intensive care unit: a pilot study |
| abstract |
Background Earlobe arterialized capillary blood gas analysis can be used to estimate arterial gas content and may be suitable for diagnosis and management of critically ill patients. However, its utility and applicability in the ICU setting remains unexplored. Methods A prospective observational validation study was designed to evaluate this technique in a cohort of mechanically ventilated adult critically ill patients admitted to a polyvalent ICU. Precision and agreement between capillary gas measures and arterial references was examined. Acute Respiratory Distress Syndrome (ARDS) diagnosis capabilities with the proposed technique were also evaluated. Finally, factors associated with sampling failure were explored. Results Fifty-five patients were included into this study. Precision of capillary samples was high (Coefficient of Variation $ PO_{2} $ = 9.8%, $ PCO_{2} $ = 7.7%, pH = 0.3%). $ PO_{2} $ measures showed insufficient agreement levels (Concordance Correlation Coefficient = 0.45; bias = 12 mmHg; percentage of error = 19.3%), whereas better agreement was observed for $ PCO_{2} $ and pH (Concordance Correlation Coefficient = 0.94 and 0.93 respectively; depreciable bias; percentage of error 11.4% and 0.5% respectively). The sensitivity and specificity for diagnosing ARDS were 100% and 92.3% using capillary gasometric measures. Sampling was unsuccessful in 43.6% of cases due to insufficient blood flow. Age > 65 years was independently associated with failure (odds ratio = 1.6), however hemodynamic failure and norepinephrine treatment were also influencing factors. Conclusions Earlobe capillary blood gas analysis is precise and can be useful for detecting extreme gasometrical values. Diagnosis of ARDS can be done accurately using capillary measurements. Although this technique may be insufficient for precise management of patients in the ICU, it has the potential for important benefits in the acute phase of various critical conditions and in other critical care arenas, such as in emergency medicine, advanced medical transport and pre-hospital critical care. |
| abstractGer |
Background Earlobe arterialized capillary blood gas analysis can be used to estimate arterial gas content and may be suitable for diagnosis and management of critically ill patients. However, its utility and applicability in the ICU setting remains unexplored. Methods A prospective observational validation study was designed to evaluate this technique in a cohort of mechanically ventilated adult critically ill patients admitted to a polyvalent ICU. Precision and agreement between capillary gas measures and arterial references was examined. Acute Respiratory Distress Syndrome (ARDS) diagnosis capabilities with the proposed technique were also evaluated. Finally, factors associated with sampling failure were explored. Results Fifty-five patients were included into this study. Precision of capillary samples was high (Coefficient of Variation $ PO_{2} $ = 9.8%, $ PCO_{2} $ = 7.7%, pH = 0.3%). $ PO_{2} $ measures showed insufficient agreement levels (Concordance Correlation Coefficient = 0.45; bias = 12 mmHg; percentage of error = 19.3%), whereas better agreement was observed for $ PCO_{2} $ and pH (Concordance Correlation Coefficient = 0.94 and 0.93 respectively; depreciable bias; percentage of error 11.4% and 0.5% respectively). The sensitivity and specificity for diagnosing ARDS were 100% and 92.3% using capillary gasometric measures. Sampling was unsuccessful in 43.6% of cases due to insufficient blood flow. Age > 65 years was independently associated with failure (odds ratio = 1.6), however hemodynamic failure and norepinephrine treatment were also influencing factors. Conclusions Earlobe capillary blood gas analysis is precise and can be useful for detecting extreme gasometrical values. Diagnosis of ARDS can be done accurately using capillary measurements. Although this technique may be insufficient for precise management of patients in the ICU, it has the potential for important benefits in the acute phase of various critical conditions and in other critical care arenas, such as in emergency medicine, advanced medical transport and pre-hospital critical care. |
| abstract_unstemmed |
Background Earlobe arterialized capillary blood gas analysis can be used to estimate arterial gas content and may be suitable for diagnosis and management of critically ill patients. However, its utility and applicability in the ICU setting remains unexplored. Methods A prospective observational validation study was designed to evaluate this technique in a cohort of mechanically ventilated adult critically ill patients admitted to a polyvalent ICU. Precision and agreement between capillary gas measures and arterial references was examined. Acute Respiratory Distress Syndrome (ARDS) diagnosis capabilities with the proposed technique were also evaluated. Finally, factors associated with sampling failure were explored. Results Fifty-five patients were included into this study. Precision of capillary samples was high (Coefficient of Variation $ PO_{2} $ = 9.8%, $ PCO_{2} $ = 7.7%, pH = 0.3%). $ PO_{2} $ measures showed insufficient agreement levels (Concordance Correlation Coefficient = 0.45; bias = 12 mmHg; percentage of error = 19.3%), whereas better agreement was observed for $ PCO_{2} $ and pH (Concordance Correlation Coefficient = 0.94 and 0.93 respectively; depreciable bias; percentage of error 11.4% and 0.5% respectively). The sensitivity and specificity for diagnosing ARDS were 100% and 92.3% using capillary gasometric measures. Sampling was unsuccessful in 43.6% of cases due to insufficient blood flow. Age > 65 years was independently associated with failure (odds ratio = 1.6), however hemodynamic failure and norepinephrine treatment were also influencing factors. Conclusions Earlobe capillary blood gas analysis is precise and can be useful for detecting extreme gasometrical values. Diagnosis of ARDS can be done accurately using capillary measurements. Although this technique may be insufficient for precise management of patients in the ICU, it has the potential for important benefits in the acute phase of various critical conditions and in other critical care arenas, such as in emergency medicine, advanced medical transport and pre-hospital critical care. |
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Earlobe arterialized capillary blood gas analysis in the intensive care unit: a pilot study |
| url |
https://dx.doi.org/10.1186/2110-5820-4-11 |
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Masip, Jordi Gili, Gisela Gomà, Gemma Oliva, Joan Carles Frechette, Alexandre Evetts, Simon Russomano, Thais Artigas, Antonio |
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Masip, Jordi Gili, Gisela Gomà, Gemma Oliva, Joan Carles Frechette, Alexandre Evetts, Simon Russomano, Thais Artigas, Antonio |
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However, its utility and applicability in the ICU setting remains unexplored. Methods A prospective observational validation study was designed to evaluate this technique in a cohort of mechanically ventilated adult critically ill patients admitted to a polyvalent ICU. Precision and agreement between capillary gas measures and arterial references was examined. Acute Respiratory Distress Syndrome (ARDS) diagnosis capabilities with the proposed technique were also evaluated. Finally, factors associated with sampling failure were explored. Results Fifty-five patients were included into this study. Precision of capillary samples was high (Coefficient of Variation $ PO_{2} $ = 9.8%, $ PCO_{2} $ = 7.7%, pH = 0.3%). $ PO_{2} $ measures showed insufficient agreement levels (Concordance Correlation Coefficient = 0.45; bias = 12 mmHg; percentage of error = 19.3%), whereas better agreement was observed for $ PCO_{2} $ and pH (Concordance Correlation Coefficient = 0.94 and 0.93 respectively; depreciable bias; percentage of error 11.4% and 0.5% respectively). The sensitivity and specificity for diagnosing ARDS were 100% and 92.3% using capillary gasometric measures. Sampling was unsuccessful in 43.6% of cases due to insufficient blood flow. Age > 65 years was independently associated with failure (odds ratio = 1.6), however hemodynamic failure and norepinephrine treatment were also influencing factors. Conclusions Earlobe capillary blood gas analysis is precise and can be useful for detecting extreme gasometrical values. 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