Tuberculosis examination using whole blood interferon-gamma release assay among health care workers in a Japanese hospital without tuberculosis-specific wards

Abstract Occupational latent tuberculosis infection (LTBI) among health care workers (HCWs) is an important public health issue. The objective of this study is to assess prevalence and risk factors of LTBI among Japanese HCWs by Quantiferon-TB Gold in Tube (QFT-GIT) and the structured questionnaire....
Ausführliche Beschreibung

Gespeichert in:

Autor*in:	Adachi, Eisuke [verfasserIn] Kogayu, Mika [verfasserIn] Fujii, Takeshi [verfasserIn] Mae, Hiroshi [verfasserIn] Shimizu, Shoichi [verfasserIn] Iwai, Yuichi [verfasserIn] Shibata, Hiroko [verfasserIn] Suzuki, Masato [verfasserIn] Imai, Kohzoh [verfasserIn] Koibuchi, Tomohiko [verfasserIn]

Format:	E-Artikel
Sprache:	Englisch

Erschienen:	2013

Schlagwörter:	Latent tuberculosis infection Quantiferon-TB gold in tube Latent tuberculosis infection baseline screening Health care workers

Übergeordnetes Werk:	Enthalten in: SpringerPlus - London : Biomed Central, 2012, 2(2013), 1 vom: 05. Sept.
Übergeordnetes Werk:	volume:2 ; year:2013 ; number:1 ; day:05 ; month:09

Links:	Volltext

DOI / URN:	10.1186/2193-1801-2-440

Katalog-ID:	SPR03275227X

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520			\|a Abstract Occupational latent tuberculosis infection (LTBI) among health care workers (HCWs) is an important public health issue. The objective of this study is to assess prevalence and risk factors of LTBI among Japanese HCWs by Quantiferon-TB Gold in Tube (QFT-GIT) and the structured questionnaire. This is a cross-sectional study involving HCWs from a hospital without tuberculosis-specific wards, receiving QFT-GIT for LTBI screening. We reviewed medical records of HCWs and questioned HCWs about exposure to M. tuberculosis and employment length in health care industries. 165 HCWs, approximately 80% of the total hospital staff, were enrolled in this study.18 out of 165 subjects had positive results, suggesting LTBI prevalence rate of 11%. Multiple regression analysis revealed a significant association between the positive or intermediate QFT-GIT results and history of contact investigation for tuberculosis. QFT-GIT positivity rate among HCWs is higher than among general population in Japan.
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allfields	10.1186/2193-1801-2-440 doi (DE-627)SPR03275227X (SPR)2193-1801-2-440-e DE-627 ger DE-627 rakwb eng 600 ASE Adachi, Eisuke verfasserin aut Tuberculosis examination using whole blood interferon-gamma release assay among health care workers in a Japanese hospital without tuberculosis-specific wards 2013 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Abstract Occupational latent tuberculosis infection (LTBI) among health care workers (HCWs) is an important public health issue. The objective of this study is to assess prevalence and risk factors of LTBI among Japanese HCWs by Quantiferon-TB Gold in Tube (QFT-GIT) and the structured questionnaire. This is a cross-sectional study involving HCWs from a hospital without tuberculosis-specific wards, receiving QFT-GIT for LTBI screening. We reviewed medical records of HCWs and questioned HCWs about exposure to M. tuberculosis and employment length in health care industries. 165 HCWs, approximately 80% of the total hospital staff, were enrolled in this study.18 out of 165 subjects had positive results, suggesting LTBI prevalence rate of 11%. Multiple regression analysis revealed a significant association between the positive or intermediate QFT-GIT results and history of contact investigation for tuberculosis. QFT-GIT positivity rate among HCWs is higher than among general population in Japan. Latent tuberculosis infection (dpeaa)DE-He213 Quantiferon-TB gold in tube (dpeaa)DE-He213 Latent tuberculosis infection baseline screening (dpeaa)DE-He213 Health care workers (dpeaa)DE-He213 Kogayu, Mika verfasserin aut Fujii, Takeshi verfasserin aut Mae, Hiroshi verfasserin aut Shimizu, Shoichi verfasserin aut Iwai, Yuichi verfasserin aut Shibata, Hiroko verfasserin aut Suzuki, Masato verfasserin aut Imai, Kohzoh verfasserin aut Koibuchi, Tomohiko verfasserin aut Enthalten in SpringerPlus London : Biomed Central, 2012 2(2013), 1 vom: 05. Sept. (DE-627)718615298 (DE-600)2661116-8 2193-1801 nnns volume:2 year:2013 number:1 day:05 month:09 https://dx.doi.org/10.1186/2193-1801-2-440 kostenfrei Volltext GBV_USEFLAG_A SYSFLAG_A GBV_SPRINGER SSG-OLC-PHA GBV_ILN_11 GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_70 GBV_ILN_73 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_171 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_370 GBV_ILN_602 GBV_ILN_2014 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4335 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 2 2013 1 05 09
spelling	10.1186/2193-1801-2-440 doi (DE-627)SPR03275227X (SPR)2193-1801-2-440-e DE-627 ger DE-627 rakwb eng 600 ASE Adachi, Eisuke verfasserin aut Tuberculosis examination using whole blood interferon-gamma release assay among health care workers in a Japanese hospital without tuberculosis-specific wards 2013 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Abstract Occupational latent tuberculosis infection (LTBI) among health care workers (HCWs) is an important public health issue. The objective of this study is to assess prevalence and risk factors of LTBI among Japanese HCWs by Quantiferon-TB Gold in Tube (QFT-GIT) and the structured questionnaire. This is a cross-sectional study involving HCWs from a hospital without tuberculosis-specific wards, receiving QFT-GIT for LTBI screening. We reviewed medical records of HCWs and questioned HCWs about exposure to M. tuberculosis and employment length in health care industries. 165 HCWs, approximately 80% of the total hospital staff, were enrolled in this study.18 out of 165 subjects had positive results, suggesting LTBI prevalence rate of 11%. Multiple regression analysis revealed a significant association between the positive or intermediate QFT-GIT results and history of contact investigation for tuberculosis. QFT-GIT positivity rate among HCWs is higher than among general population in Japan. Latent tuberculosis infection (dpeaa)DE-He213 Quantiferon-TB gold in tube (dpeaa)DE-He213 Latent tuberculosis infection baseline screening (dpeaa)DE-He213 Health care workers (dpeaa)DE-He213 Kogayu, Mika verfasserin aut Fujii, Takeshi verfasserin aut Mae, Hiroshi verfasserin aut Shimizu, Shoichi verfasserin aut Iwai, Yuichi verfasserin aut Shibata, Hiroko verfasserin aut Suzuki, Masato verfasserin aut Imai, Kohzoh verfasserin aut Koibuchi, Tomohiko verfasserin aut Enthalten in SpringerPlus London : Biomed Central, 2012 2(2013), 1 vom: 05. Sept. (DE-627)718615298 (DE-600)2661116-8 2193-1801 nnns volume:2 year:2013 number:1 day:05 month:09 https://dx.doi.org/10.1186/2193-1801-2-440 kostenfrei Volltext GBV_USEFLAG_A SYSFLAG_A GBV_SPRINGER SSG-OLC-PHA GBV_ILN_11 GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_70 GBV_ILN_73 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_171 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_370 GBV_ILN_602 GBV_ILN_2014 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4335 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 2 2013 1 05 09
allfields_unstemmed	10.1186/2193-1801-2-440 doi (DE-627)SPR03275227X (SPR)2193-1801-2-440-e DE-627 ger DE-627 rakwb eng 600 ASE Adachi, Eisuke verfasserin aut Tuberculosis examination using whole blood interferon-gamma release assay among health care workers in a Japanese hospital without tuberculosis-specific wards 2013 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Abstract Occupational latent tuberculosis infection (LTBI) among health care workers (HCWs) is an important public health issue. The objective of this study is to assess prevalence and risk factors of LTBI among Japanese HCWs by Quantiferon-TB Gold in Tube (QFT-GIT) and the structured questionnaire. This is a cross-sectional study involving HCWs from a hospital without tuberculosis-specific wards, receiving QFT-GIT for LTBI screening. We reviewed medical records of HCWs and questioned HCWs about exposure to M. tuberculosis and employment length in health care industries. 165 HCWs, approximately 80% of the total hospital staff, were enrolled in this study.18 out of 165 subjects had positive results, suggesting LTBI prevalence rate of 11%. Multiple regression analysis revealed a significant association between the positive or intermediate QFT-GIT results and history of contact investigation for tuberculosis. QFT-GIT positivity rate among HCWs is higher than among general population in Japan. Latent tuberculosis infection (dpeaa)DE-He213 Quantiferon-TB gold in tube (dpeaa)DE-He213 Latent tuberculosis infection baseline screening (dpeaa)DE-He213 Health care workers (dpeaa)DE-He213 Kogayu, Mika verfasserin aut Fujii, Takeshi verfasserin aut Mae, Hiroshi verfasserin aut Shimizu, Shoichi verfasserin aut Iwai, Yuichi verfasserin aut Shibata, Hiroko verfasserin aut Suzuki, Masato verfasserin aut Imai, Kohzoh verfasserin aut Koibuchi, Tomohiko verfasserin aut Enthalten in SpringerPlus London : Biomed Central, 2012 2(2013), 1 vom: 05. Sept. (DE-627)718615298 (DE-600)2661116-8 2193-1801 nnns volume:2 year:2013 number:1 day:05 month:09 https://dx.doi.org/10.1186/2193-1801-2-440 kostenfrei Volltext GBV_USEFLAG_A SYSFLAG_A GBV_SPRINGER SSG-OLC-PHA GBV_ILN_11 GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_70 GBV_ILN_73 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_171 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_370 GBV_ILN_602 GBV_ILN_2014 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4335 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 2 2013 1 05 09
allfieldsGer	10.1186/2193-1801-2-440 doi (DE-627)SPR03275227X (SPR)2193-1801-2-440-e DE-627 ger DE-627 rakwb eng 600 ASE Adachi, Eisuke verfasserin aut Tuberculosis examination using whole blood interferon-gamma release assay among health care workers in a Japanese hospital without tuberculosis-specific wards 2013 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Abstract Occupational latent tuberculosis infection (LTBI) among health care workers (HCWs) is an important public health issue. The objective of this study is to assess prevalence and risk factors of LTBI among Japanese HCWs by Quantiferon-TB Gold in Tube (QFT-GIT) and the structured questionnaire. This is a cross-sectional study involving HCWs from a hospital without tuberculosis-specific wards, receiving QFT-GIT for LTBI screening. We reviewed medical records of HCWs and questioned HCWs about exposure to M. tuberculosis and employment length in health care industries. 165 HCWs, approximately 80% of the total hospital staff, were enrolled in this study.18 out of 165 subjects had positive results, suggesting LTBI prevalence rate of 11%. Multiple regression analysis revealed a significant association between the positive or intermediate QFT-GIT results and history of contact investigation for tuberculosis. QFT-GIT positivity rate among HCWs is higher than among general population in Japan. Latent tuberculosis infection (dpeaa)DE-He213 Quantiferon-TB gold in tube (dpeaa)DE-He213 Latent tuberculosis infection baseline screening (dpeaa)DE-He213 Health care workers (dpeaa)DE-He213 Kogayu, Mika verfasserin aut Fujii, Takeshi verfasserin aut Mae, Hiroshi verfasserin aut Shimizu, Shoichi verfasserin aut Iwai, Yuichi verfasserin aut Shibata, Hiroko verfasserin aut Suzuki, Masato verfasserin aut Imai, Kohzoh verfasserin aut Koibuchi, Tomohiko verfasserin aut Enthalten in SpringerPlus London : Biomed Central, 2012 2(2013), 1 vom: 05. Sept. (DE-627)718615298 (DE-600)2661116-8 2193-1801 nnns volume:2 year:2013 number:1 day:05 month:09 https://dx.doi.org/10.1186/2193-1801-2-440 kostenfrei Volltext GBV_USEFLAG_A SYSFLAG_A GBV_SPRINGER SSG-OLC-PHA GBV_ILN_11 GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_70 GBV_ILN_73 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_171 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_370 GBV_ILN_602 GBV_ILN_2014 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4335 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 2 2013 1 05 09
allfieldsSound	10.1186/2193-1801-2-440 doi (DE-627)SPR03275227X (SPR)2193-1801-2-440-e DE-627 ger DE-627 rakwb eng 600 ASE Adachi, Eisuke verfasserin aut Tuberculosis examination using whole blood interferon-gamma release assay among health care workers in a Japanese hospital without tuberculosis-specific wards 2013 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Abstract Occupational latent tuberculosis infection (LTBI) among health care workers (HCWs) is an important public health issue. The objective of this study is to assess prevalence and risk factors of LTBI among Japanese HCWs by Quantiferon-TB Gold in Tube (QFT-GIT) and the structured questionnaire. This is a cross-sectional study involving HCWs from a hospital without tuberculosis-specific wards, receiving QFT-GIT for LTBI screening. We reviewed medical records of HCWs and questioned HCWs about exposure to M. tuberculosis and employment length in health care industries. 165 HCWs, approximately 80% of the total hospital staff, were enrolled in this study.18 out of 165 subjects had positive results, suggesting LTBI prevalence rate of 11%. Multiple regression analysis revealed a significant association between the positive or intermediate QFT-GIT results and history of contact investigation for tuberculosis. QFT-GIT positivity rate among HCWs is higher than among general population in Japan. Latent tuberculosis infection (dpeaa)DE-He213 Quantiferon-TB gold in tube (dpeaa)DE-He213 Latent tuberculosis infection baseline screening (dpeaa)DE-He213 Health care workers (dpeaa)DE-He213 Kogayu, Mika verfasserin aut Fujii, Takeshi verfasserin aut Mae, Hiroshi verfasserin aut Shimizu, Shoichi verfasserin aut Iwai, Yuichi verfasserin aut Shibata, Hiroko verfasserin aut Suzuki, Masato verfasserin aut Imai, Kohzoh verfasserin aut Koibuchi, Tomohiko verfasserin aut Enthalten in SpringerPlus London : Biomed Central, 2012 2(2013), 1 vom: 05. Sept. (DE-627)718615298 (DE-600)2661116-8 2193-1801 nnns volume:2 year:2013 number:1 day:05 month:09 https://dx.doi.org/10.1186/2193-1801-2-440 kostenfrei Volltext GBV_USEFLAG_A SYSFLAG_A GBV_SPRINGER SSG-OLC-PHA GBV_ILN_11 GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_70 GBV_ILN_73 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_171 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_370 GBV_ILN_602 GBV_ILN_2014 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4335 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 2 2013 1 05 09
language	English
source	Enthalten in SpringerPlus 2(2013), 1 vom: 05. Sept. volume:2 year:2013 number:1 day:05 month:09
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topic_facet	Latent tuberculosis infection Quantiferon-TB gold in tube Latent tuberculosis infection baseline screening Health care workers
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authorswithroles_txt_mv	Adachi, Eisuke @@aut@@ Kogayu, Mika @@aut@@ Fujii, Takeshi @@aut@@ Mae, Hiroshi @@aut@@ Shimizu, Shoichi @@aut@@ Iwai, Yuichi @@aut@@ Shibata, Hiroko @@aut@@ Suzuki, Masato @@aut@@ Imai, Kohzoh @@aut@@ Koibuchi, Tomohiko @@aut@@
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author	Adachi, Eisuke
spellingShingle	Adachi, Eisuke ddc 600 misc Latent tuberculosis infection misc Quantiferon-TB gold in tube misc Latent tuberculosis infection baseline screening misc Health care workers Tuberculosis examination using whole blood interferon-gamma release assay among health care workers in a Japanese hospital without tuberculosis-specific wards
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topic_title	600 ASE Tuberculosis examination using whole blood interferon-gamma release assay among health care workers in a Japanese hospital without tuberculosis-specific wards Latent tuberculosis infection (dpeaa)DE-He213 Quantiferon-TB gold in tube (dpeaa)DE-He213 Latent tuberculosis infection baseline screening (dpeaa)DE-He213 Health care workers (dpeaa)DE-He213
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title	Tuberculosis examination using whole blood interferon-gamma release assay among health care workers in a Japanese hospital without tuberculosis-specific wards
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title_full	Tuberculosis examination using whole blood interferon-gamma release assay among health care workers in a Japanese hospital without tuberculosis-specific wards
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author_browse	Adachi, Eisuke Kogayu, Mika Fujii, Takeshi Mae, Hiroshi Shimizu, Shoichi Iwai, Yuichi Shibata, Hiroko Suzuki, Masato Imai, Kohzoh Koibuchi, Tomohiko
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title_sort	tuberculosis examination using whole blood interferon-gamma release assay among health care workers in a japanese hospital without tuberculosis-specific wards
title_auth	Tuberculosis examination using whole blood interferon-gamma release assay among health care workers in a Japanese hospital without tuberculosis-specific wards
abstract	Abstract Occupational latent tuberculosis infection (LTBI) among health care workers (HCWs) is an important public health issue. The objective of this study is to assess prevalence and risk factors of LTBI among Japanese HCWs by Quantiferon-TB Gold in Tube (QFT-GIT) and the structured questionnaire. This is a cross-sectional study involving HCWs from a hospital without tuberculosis-specific wards, receiving QFT-GIT for LTBI screening. We reviewed medical records of HCWs and questioned HCWs about exposure to M. tuberculosis and employment length in health care industries. 165 HCWs, approximately 80% of the total hospital staff, were enrolled in this study.18 out of 165 subjects had positive results, suggesting LTBI prevalence rate of 11%. Multiple regression analysis revealed a significant association between the positive or intermediate QFT-GIT results and history of contact investigation for tuberculosis. QFT-GIT positivity rate among HCWs is higher than among general population in Japan.
abstractGer	Abstract Occupational latent tuberculosis infection (LTBI) among health care workers (HCWs) is an important public health issue. The objective of this study is to assess prevalence and risk factors of LTBI among Japanese HCWs by Quantiferon-TB Gold in Tube (QFT-GIT) and the structured questionnaire. This is a cross-sectional study involving HCWs from a hospital without tuberculosis-specific wards, receiving QFT-GIT for LTBI screening. We reviewed medical records of HCWs and questioned HCWs about exposure to M. tuberculosis and employment length in health care industries. 165 HCWs, approximately 80% of the total hospital staff, were enrolled in this study.18 out of 165 subjects had positive results, suggesting LTBI prevalence rate of 11%. Multiple regression analysis revealed a significant association between the positive or intermediate QFT-GIT results and history of contact investigation for tuberculosis. QFT-GIT positivity rate among HCWs is higher than among general population in Japan.
abstract_unstemmed	Abstract Occupational latent tuberculosis infection (LTBI) among health care workers (HCWs) is an important public health issue. The objective of this study is to assess prevalence and risk factors of LTBI among Japanese HCWs by Quantiferon-TB Gold in Tube (QFT-GIT) and the structured questionnaire. This is a cross-sectional study involving HCWs from a hospital without tuberculosis-specific wards, receiving QFT-GIT for LTBI screening. We reviewed medical records of HCWs and questioned HCWs about exposure to M. tuberculosis and employment length in health care industries. 165 HCWs, approximately 80% of the total hospital staff, were enrolled in this study.18 out of 165 subjects had positive results, suggesting LTBI prevalence rate of 11%. Multiple regression analysis revealed a significant association between the positive or intermediate QFT-GIT results and history of contact investigation for tuberculosis. QFT-GIT positivity rate among HCWs is higher than among general population in Japan.
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title_short	Tuberculosis examination using whole blood interferon-gamma release assay among health care workers in a Japanese hospital without tuberculosis-specific wards
url	https://dx.doi.org/10.1186/2193-1801-2-440
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author2	Kogayu, Mika Fujii, Takeshi Mae, Hiroshi Shimizu, Shoichi Iwai, Yuichi Shibata, Hiroko Suzuki, Masato Imai, Kohzoh Koibuchi, Tomohiko
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The objective of this study is to assess prevalence and risk factors of LTBI among Japanese HCWs by Quantiferon-TB Gold in Tube (QFT-GIT) and the structured questionnaire. This is a cross-sectional study involving HCWs from a hospital without tuberculosis-specific wards, receiving QFT-GIT for LTBI screening. We reviewed medical records of HCWs and questioned HCWs about exposure to M. tuberculosis and employment length in health care industries. 165 HCWs, approximately 80% of the total hospital staff, were enrolled in this study.18 out of 165 subjects had positive results, suggesting LTBI prevalence rate of 11%. Multiple regression analysis revealed a significant association between the positive or intermediate QFT-GIT results and history of contact investigation for tuberculosis. 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Tuberculosis examination using whole blood interferon-gamma release assay among health care workers in a Japanese hospital without tuberculosis-specific wards

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