Mobility and increased risk of HIV acquisition in South Africa: a mixed-method systematic review protocol

Background In South Africa (home of the largest HIV epidemic globally), there are high levels of mobility. While studies produced in the recent past provide useful perspectives to the mobility-HIV risk linkage, systematic analyses are needed for in-depth understanding of the complex dynamics between mobility and HIV risk. We plan to undertake an evidence-based review of existing literature connecting mobility and increased risky sexual behavior as well as risk of HIV acquisition in South Africa. Methods/design We will conduct a mixed-method systematic review of peer-reviewed studies published between 2000 and 2015. In particular, we will search for relevant South African studies from the following databases: MEDLINE, EMBASE, Web of Science, and J-STOR databases. Studies explicitly examining HIV and labor migration will be eligible for inclusion, while non-empirical work and other studies on key vulnerable populations such as commercial sex workers (CSW) and men who have sex with men (MSM) will be excluded. Discussion The proposed mixed-method systematic review will employ a three-phase sequential approach [i.e., (i) identifying relevant studies through data extraction (validated by use of Distiller-SR data management software), (ii) qualitative synthesis, and (iii) quantitative synthesis including meta-analysis data]. Recurrent ideas and conclusions from syntheses will be compiled into key themes and further processed into categories and sub-themes constituting the primary and secondary outcomes of this study. Synthesis of main findings from different studies examining the subject issue here may uncover important research gaps in this literature, laying a strong foundation for research and development of sustainable localized migrant-specific HIV prevention strategies in South Africa. Systematic review registration Our protocol was registered with PROSPERO under registration number: CRD 42017055580. (https://www.crd.york.ac.uk/PROSPERO/display_record.asp?ID=CRD42017055580) Ausführliche Beschreibung

Gespeichert in:

Autor*in:	Dzomba, Armstrong [verfasserIn] Govender, Kaymarlin [verfasserIn] Mashamba-Thompson, Tivani P. [verfasserIn] Tanser, Frank [verfasserIn]

Format:	E-Artikel
Sprache:	Englisch

Erschienen:	2018

Schlagwörter:	Sexual risk behavior Migrants HIV risk acquisition South Africa

Übergeordnetes Werk:	Enthalten in: Systematic Reviews - London : Biomed Central, 2012, 7(2018), 1 vom: 27. Feb.
Übergeordnetes Werk:	volume:7 ; year:2018 ; number:1 ; day:27 ; month:02

Links:	Volltext

DOI / URN:	10.1186/s13643-018-0703-z

Katalog-ID:	SPR032895348

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allfields	10.1186/s13643-018-0703-z doi (DE-627)SPR032895348 (SPR)s13643-018-0703-z-e DE-627 ger DE-627 rakwb eng 610 ASE Dzomba, Armstrong verfasserin aut Mobility and increased risk of HIV acquisition in South Africa: a mixed-method systematic review protocol 2018 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Background In South Africa (home of the largest HIV epidemic globally), there are high levels of mobility. While studies produced in the recent past provide useful perspectives to the mobility-HIV risk linkage, systematic analyses are needed for in-depth understanding of the complex dynamics between mobility and HIV risk. We plan to undertake an evidence-based review of existing literature connecting mobility and increased risky sexual behavior as well as risk of HIV acquisition in South Africa. Methods/design We will conduct a mixed-method systematic review of peer-reviewed studies published between 2000 and 2015. In particular, we will search for relevant South African studies from the following databases: MEDLINE, EMBASE, Web of Science, and J-STOR databases. Studies explicitly examining HIV and labor migration will be eligible for inclusion, while non-empirical work and other studies on key vulnerable populations such as commercial sex workers (CSW) and men who have sex with men (MSM) will be excluded. Discussion The proposed mixed-method systematic review will employ a three-phase sequential approach [i.e., (i) identifying relevant studies through data extraction (validated by use of Distiller-SR data management software), (ii) qualitative synthesis, and (iii) quantitative synthesis including meta-analysis data]. Recurrent ideas and conclusions from syntheses will be compiled into key themes and further processed into categories and sub-themes constituting the primary and secondary outcomes of this study. Synthesis of main findings from different studies examining the subject issue here may uncover important research gaps in this literature, laying a strong foundation for research and development of sustainable localized migrant-specific HIV prevention strategies in South Africa. Systematic review registration Our protocol was registered with PROSPERO under registration number: CRD 42017055580. (https://www.crd.york.ac.uk/PROSPERO/display_record.asp?ID=CRD42017055580) Sexual risk behavior (dpeaa)DE-He213 Migrants (dpeaa)DE-He213 HIV risk acquisition (dpeaa)DE-He213 South Africa (dpeaa)DE-He213 Govender, Kaymarlin verfasserin aut Mashamba-Thompson, Tivani P. verfasserin aut Tanser, Frank verfasserin aut Enthalten in Systematic Reviews London : Biomed Central, 2012 7(2018), 1 vom: 27. Feb. (DE-627)718627210 (DE-600)2662257-9 2046-4053 nnns volume:7 year:2018 number:1 day:27 month:02 https://dx.doi.org/10.1186/s13643-018-0703-z kostenfrei Volltext GBV_USEFLAG_A SYSFLAG_A GBV_SPRINGER SSG-OLC-PHA GBV_ILN_11 GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_2003 GBV_ILN_2005 GBV_ILN_2009 GBV_ILN_2014 GBV_ILN_2055 GBV_ILN_2111 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 7 2018 1 27 02
spelling	10.1186/s13643-018-0703-z doi (DE-627)SPR032895348 (SPR)s13643-018-0703-z-e DE-627 ger DE-627 rakwb eng 610 ASE Dzomba, Armstrong verfasserin aut Mobility and increased risk of HIV acquisition in South Africa: a mixed-method systematic review protocol 2018 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Background In South Africa (home of the largest HIV epidemic globally), there are high levels of mobility. While studies produced in the recent past provide useful perspectives to the mobility-HIV risk linkage, systematic analyses are needed for in-depth understanding of the complex dynamics between mobility and HIV risk. We plan to undertake an evidence-based review of existing literature connecting mobility and increased risky sexual behavior as well as risk of HIV acquisition in South Africa. Methods/design We will conduct a mixed-method systematic review of peer-reviewed studies published between 2000 and 2015. In particular, we will search for relevant South African studies from the following databases: MEDLINE, EMBASE, Web of Science, and J-STOR databases. Studies explicitly examining HIV and labor migration will be eligible for inclusion, while non-empirical work and other studies on key vulnerable populations such as commercial sex workers (CSW) and men who have sex with men (MSM) will be excluded. Discussion The proposed mixed-method systematic review will employ a three-phase sequential approach [i.e., (i) identifying relevant studies through data extraction (validated by use of Distiller-SR data management software), (ii) qualitative synthesis, and (iii) quantitative synthesis including meta-analysis data]. Recurrent ideas and conclusions from syntheses will be compiled into key themes and further processed into categories and sub-themes constituting the primary and secondary outcomes of this study. Synthesis of main findings from different studies examining the subject issue here may uncover important research gaps in this literature, laying a strong foundation for research and development of sustainable localized migrant-specific HIV prevention strategies in South Africa. Systematic review registration Our protocol was registered with PROSPERO under registration number: CRD 42017055580. (https://www.crd.york.ac.uk/PROSPERO/display_record.asp?ID=CRD42017055580) Sexual risk behavior (dpeaa)DE-He213 Migrants (dpeaa)DE-He213 HIV risk acquisition (dpeaa)DE-He213 South Africa (dpeaa)DE-He213 Govender, Kaymarlin verfasserin aut Mashamba-Thompson, Tivani P. verfasserin aut Tanser, Frank verfasserin aut Enthalten in Systematic Reviews London : Biomed Central, 2012 7(2018), 1 vom: 27. Feb. (DE-627)718627210 (DE-600)2662257-9 2046-4053 nnns volume:7 year:2018 number:1 day:27 month:02 https://dx.doi.org/10.1186/s13643-018-0703-z kostenfrei Volltext GBV_USEFLAG_A SYSFLAG_A GBV_SPRINGER SSG-OLC-PHA GBV_ILN_11 GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_2003 GBV_ILN_2005 GBV_ILN_2009 GBV_ILN_2014 GBV_ILN_2055 GBV_ILN_2111 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 7 2018 1 27 02
allfields_unstemmed	10.1186/s13643-018-0703-z doi (DE-627)SPR032895348 (SPR)s13643-018-0703-z-e DE-627 ger DE-627 rakwb eng 610 ASE Dzomba, Armstrong verfasserin aut Mobility and increased risk of HIV acquisition in South Africa: a mixed-method systematic review protocol 2018 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Background In South Africa (home of the largest HIV epidemic globally), there are high levels of mobility. While studies produced in the recent past provide useful perspectives to the mobility-HIV risk linkage, systematic analyses are needed for in-depth understanding of the complex dynamics between mobility and HIV risk. We plan to undertake an evidence-based review of existing literature connecting mobility and increased risky sexual behavior as well as risk of HIV acquisition in South Africa. Methods/design We will conduct a mixed-method systematic review of peer-reviewed studies published between 2000 and 2015. In particular, we will search for relevant South African studies from the following databases: MEDLINE, EMBASE, Web of Science, and J-STOR databases. Studies explicitly examining HIV and labor migration will be eligible for inclusion, while non-empirical work and other studies on key vulnerable populations such as commercial sex workers (CSW) and men who have sex with men (MSM) will be excluded. Discussion The proposed mixed-method systematic review will employ a three-phase sequential approach [i.e., (i) identifying relevant studies through data extraction (validated by use of Distiller-SR data management software), (ii) qualitative synthesis, and (iii) quantitative synthesis including meta-analysis data]. Recurrent ideas and conclusions from syntheses will be compiled into key themes and further processed into categories and sub-themes constituting the primary and secondary outcomes of this study. Synthesis of main findings from different studies examining the subject issue here may uncover important research gaps in this literature, laying a strong foundation for research and development of sustainable localized migrant-specific HIV prevention strategies in South Africa. Systematic review registration Our protocol was registered with PROSPERO under registration number: CRD 42017055580. (https://www.crd.york.ac.uk/PROSPERO/display_record.asp?ID=CRD42017055580) Sexual risk behavior (dpeaa)DE-He213 Migrants (dpeaa)DE-He213 HIV risk acquisition (dpeaa)DE-He213 South Africa (dpeaa)DE-He213 Govender, Kaymarlin verfasserin aut Mashamba-Thompson, Tivani P. verfasserin aut Tanser, Frank verfasserin aut Enthalten in Systematic Reviews London : Biomed Central, 2012 7(2018), 1 vom: 27. Feb. (DE-627)718627210 (DE-600)2662257-9 2046-4053 nnns volume:7 year:2018 number:1 day:27 month:02 https://dx.doi.org/10.1186/s13643-018-0703-z kostenfrei Volltext GBV_USEFLAG_A SYSFLAG_A GBV_SPRINGER SSG-OLC-PHA GBV_ILN_11 GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_2003 GBV_ILN_2005 GBV_ILN_2009 GBV_ILN_2014 GBV_ILN_2055 GBV_ILN_2111 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 7 2018 1 27 02
allfieldsGer	10.1186/s13643-018-0703-z doi (DE-627)SPR032895348 (SPR)s13643-018-0703-z-e DE-627 ger DE-627 rakwb eng 610 ASE Dzomba, Armstrong verfasserin aut Mobility and increased risk of HIV acquisition in South Africa: a mixed-method systematic review protocol 2018 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Background In South Africa (home of the largest HIV epidemic globally), there are high levels of mobility. While studies produced in the recent past provide useful perspectives to the mobility-HIV risk linkage, systematic analyses are needed for in-depth understanding of the complex dynamics between mobility and HIV risk. We plan to undertake an evidence-based review of existing literature connecting mobility and increased risky sexual behavior as well as risk of HIV acquisition in South Africa. Methods/design We will conduct a mixed-method systematic review of peer-reviewed studies published between 2000 and 2015. In particular, we will search for relevant South African studies from the following databases: MEDLINE, EMBASE, Web of Science, and J-STOR databases. Studies explicitly examining HIV and labor migration will be eligible for inclusion, while non-empirical work and other studies on key vulnerable populations such as commercial sex workers (CSW) and men who have sex with men (MSM) will be excluded. Discussion The proposed mixed-method systematic review will employ a three-phase sequential approach [i.e., (i) identifying relevant studies through data extraction (validated by use of Distiller-SR data management software), (ii) qualitative synthesis, and (iii) quantitative synthesis including meta-analysis data]. Recurrent ideas and conclusions from syntheses will be compiled into key themes and further processed into categories and sub-themes constituting the primary and secondary outcomes of this study. Synthesis of main findings from different studies examining the subject issue here may uncover important research gaps in this literature, laying a strong foundation for research and development of sustainable localized migrant-specific HIV prevention strategies in South Africa. Systematic review registration Our protocol was registered with PROSPERO under registration number: CRD 42017055580. (https://www.crd.york.ac.uk/PROSPERO/display_record.asp?ID=CRD42017055580) Sexual risk behavior (dpeaa)DE-He213 Migrants (dpeaa)DE-He213 HIV risk acquisition (dpeaa)DE-He213 South Africa (dpeaa)DE-He213 Govender, Kaymarlin verfasserin aut Mashamba-Thompson, Tivani P. verfasserin aut Tanser, Frank verfasserin aut Enthalten in Systematic Reviews London : Biomed Central, 2012 7(2018), 1 vom: 27. Feb. (DE-627)718627210 (DE-600)2662257-9 2046-4053 nnns volume:7 year:2018 number:1 day:27 month:02 https://dx.doi.org/10.1186/s13643-018-0703-z kostenfrei Volltext GBV_USEFLAG_A SYSFLAG_A GBV_SPRINGER SSG-OLC-PHA GBV_ILN_11 GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_2003 GBV_ILN_2005 GBV_ILN_2009 GBV_ILN_2014 GBV_ILN_2055 GBV_ILN_2111 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 7 2018 1 27 02
allfieldsSound	10.1186/s13643-018-0703-z doi (DE-627)SPR032895348 (SPR)s13643-018-0703-z-e DE-627 ger DE-627 rakwb eng 610 ASE Dzomba, Armstrong verfasserin aut Mobility and increased risk of HIV acquisition in South Africa: a mixed-method systematic review protocol 2018 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Background In South Africa (home of the largest HIV epidemic globally), there are high levels of mobility. While studies produced in the recent past provide useful perspectives to the mobility-HIV risk linkage, systematic analyses are needed for in-depth understanding of the complex dynamics between mobility and HIV risk. We plan to undertake an evidence-based review of existing literature connecting mobility and increased risky sexual behavior as well as risk of HIV acquisition in South Africa. Methods/design We will conduct a mixed-method systematic review of peer-reviewed studies published between 2000 and 2015. In particular, we will search for relevant South African studies from the following databases: MEDLINE, EMBASE, Web of Science, and J-STOR databases. Studies explicitly examining HIV and labor migration will be eligible for inclusion, while non-empirical work and other studies on key vulnerable populations such as commercial sex workers (CSW) and men who have sex with men (MSM) will be excluded. Discussion The proposed mixed-method systematic review will employ a three-phase sequential approach [i.e., (i) identifying relevant studies through data extraction (validated by use of Distiller-SR data management software), (ii) qualitative synthesis, and (iii) quantitative synthesis including meta-analysis data]. Recurrent ideas and conclusions from syntheses will be compiled into key themes and further processed into categories and sub-themes constituting the primary and secondary outcomes of this study. Synthesis of main findings from different studies examining the subject issue here may uncover important research gaps in this literature, laying a strong foundation for research and development of sustainable localized migrant-specific HIV prevention strategies in South Africa. Systematic review registration Our protocol was registered with PROSPERO under registration number: CRD 42017055580. (https://www.crd.york.ac.uk/PROSPERO/display_record.asp?ID=CRD42017055580) Sexual risk behavior (dpeaa)DE-He213 Migrants (dpeaa)DE-He213 HIV risk acquisition (dpeaa)DE-He213 South Africa (dpeaa)DE-He213 Govender, Kaymarlin verfasserin aut Mashamba-Thompson, Tivani P. verfasserin aut Tanser, Frank verfasserin aut Enthalten in Systematic Reviews London : Biomed Central, 2012 7(2018), 1 vom: 27. Feb. (DE-627)718627210 (DE-600)2662257-9 2046-4053 nnns volume:7 year:2018 number:1 day:27 month:02 https://dx.doi.org/10.1186/s13643-018-0703-z kostenfrei Volltext GBV_USEFLAG_A SYSFLAG_A GBV_SPRINGER SSG-OLC-PHA GBV_ILN_11 GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_2003 GBV_ILN_2005 GBV_ILN_2009 GBV_ILN_2014 GBV_ILN_2055 GBV_ILN_2111 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 7 2018 1 27 02
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title	Mobility and increased risk of HIV acquisition in South Africa: a mixed-method systematic review protocol
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title_full	Mobility and increased risk of HIV acquisition in South Africa: a mixed-method systematic review protocol
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title_sort	mobility and increased risk of hiv acquisition in south africa: a mixed-method systematic review protocol
title_auth	Mobility and increased risk of HIV acquisition in South Africa: a mixed-method systematic review protocol
abstract	Background In South Africa (home of the largest HIV epidemic globally), there are high levels of mobility. While studies produced in the recent past provide useful perspectives to the mobility-HIV risk linkage, systematic analyses are needed for in-depth understanding of the complex dynamics between mobility and HIV risk. We plan to undertake an evidence-based review of existing literature connecting mobility and increased risky sexual behavior as well as risk of HIV acquisition in South Africa. Methods/design We will conduct a mixed-method systematic review of peer-reviewed studies published between 2000 and 2015. In particular, we will search for relevant South African studies from the following databases: MEDLINE, EMBASE, Web of Science, and J-STOR databases. Studies explicitly examining HIV and labor migration will be eligible for inclusion, while non-empirical work and other studies on key vulnerable populations such as commercial sex workers (CSW) and men who have sex with men (MSM) will be excluded. Discussion The proposed mixed-method systematic review will employ a three-phase sequential approach [i.e., (i) identifying relevant studies through data extraction (validated by use of Distiller-SR data management software), (ii) qualitative synthesis, and (iii) quantitative synthesis including meta-analysis data]. Recurrent ideas and conclusions from syntheses will be compiled into key themes and further processed into categories and sub-themes constituting the primary and secondary outcomes of this study. Synthesis of main findings from different studies examining the subject issue here may uncover important research gaps in this literature, laying a strong foundation for research and development of sustainable localized migrant-specific HIV prevention strategies in South Africa. Systematic review registration Our protocol was registered with PROSPERO under registration number: CRD 42017055580. (https://www.crd.york.ac.uk/PROSPERO/display_record.asp?ID=CRD42017055580)
abstractGer	Background In South Africa (home of the largest HIV epidemic globally), there are high levels of mobility. While studies produced in the recent past provide useful perspectives to the mobility-HIV risk linkage, systematic analyses are needed for in-depth understanding of the complex dynamics between mobility and HIV risk. We plan to undertake an evidence-based review of existing literature connecting mobility and increased risky sexual behavior as well as risk of HIV acquisition in South Africa. Methods/design We will conduct a mixed-method systematic review of peer-reviewed studies published between 2000 and 2015. In particular, we will search for relevant South African studies from the following databases: MEDLINE, EMBASE, Web of Science, and J-STOR databases. Studies explicitly examining HIV and labor migration will be eligible for inclusion, while non-empirical work and other studies on key vulnerable populations such as commercial sex workers (CSW) and men who have sex with men (MSM) will be excluded. Discussion The proposed mixed-method systematic review will employ a three-phase sequential approach [i.e., (i) identifying relevant studies through data extraction (validated by use of Distiller-SR data management software), (ii) qualitative synthesis, and (iii) quantitative synthesis including meta-analysis data]. Recurrent ideas and conclusions from syntheses will be compiled into key themes and further processed into categories and sub-themes constituting the primary and secondary outcomes of this study. Synthesis of main findings from different studies examining the subject issue here may uncover important research gaps in this literature, laying a strong foundation for research and development of sustainable localized migrant-specific HIV prevention strategies in South Africa. Systematic review registration Our protocol was registered with PROSPERO under registration number: CRD 42017055580. (https://www.crd.york.ac.uk/PROSPERO/display_record.asp?ID=CRD42017055580)
abstract_unstemmed	Background In South Africa (home of the largest HIV epidemic globally), there are high levels of mobility. While studies produced in the recent past provide useful perspectives to the mobility-HIV risk linkage, systematic analyses are needed for in-depth understanding of the complex dynamics between mobility and HIV risk. We plan to undertake an evidence-based review of existing literature connecting mobility and increased risky sexual behavior as well as risk of HIV acquisition in South Africa. Methods/design We will conduct a mixed-method systematic review of peer-reviewed studies published between 2000 and 2015. In particular, we will search for relevant South African studies from the following databases: MEDLINE, EMBASE, Web of Science, and J-STOR databases. Studies explicitly examining HIV and labor migration will be eligible for inclusion, while non-empirical work and other studies on key vulnerable populations such as commercial sex workers (CSW) and men who have sex with men (MSM) will be excluded. Discussion The proposed mixed-method systematic review will employ a three-phase sequential approach [i.e., (i) identifying relevant studies through data extraction (validated by use of Distiller-SR data management software), (ii) qualitative synthesis, and (iii) quantitative synthesis including meta-analysis data]. Recurrent ideas and conclusions from syntheses will be compiled into key themes and further processed into categories and sub-themes constituting the primary and secondary outcomes of this study. Synthesis of main findings from different studies examining the subject issue here may uncover important research gaps in this literature, laying a strong foundation for research and development of sustainable localized migrant-specific HIV prevention strategies in South Africa. Systematic review registration Our protocol was registered with PROSPERO under registration number: CRD 42017055580. (https://www.crd.york.ac.uk/PROSPERO/display_record.asp?ID=CRD42017055580)
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title_short	Mobility and increased risk of HIV acquisition in South Africa: a mixed-method systematic review protocol
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author2	Govender, Kaymarlin Mashamba-Thompson, Tivani P. Tanser, Frank
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Discussion The proposed mixed-method systematic review will employ a three-phase sequential approach [i.e., (i) identifying relevant studies through data extraction (validated by use of Distiller-SR data management software), (ii) qualitative synthesis, and (iii) quantitative synthesis including meta-analysis data]. Recurrent ideas and conclusions from syntheses will be compiled into key themes and further processed into categories and sub-themes constituting the primary and secondary outcomes of this study. Synthesis of main findings from different studies examining the subject issue here may uncover important research gaps in this literature, laying a strong foundation for research and development of sustainable localized migrant-specific HIV prevention strategies in South Africa. Systematic review registration Our protocol was registered with PROSPERO under registration number: CRD 42017055580. 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Mobility and increased risk of HIV acquisition in South Africa: a mixed-method systematic review protocol

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