Design, Synthesis and Insecticidal Activities of Novel 5-Alkoxyfuran-2(5H)-one Derivatives
Abstract A series of novel 5-alkoxyfuran-2(5H)-one derivatives was synthesized, and characterized by 1H NMR, 13C NMR and HRMS. Biological activities of all the title compounds were evaluated systematically. Preliminary bioassays indicated that most of the compounds exhibited moderate insecticidal ac...
Ausführliche Beschreibung
Gespeichert in:
| Autor*in: |
Wang, Xianhao [verfasserIn] Li, Jianguo [verfasserIn] Wang, Guangjian [verfasserIn] Han, Xianzheng [verfasserIn] Li, Dongmei [verfasserIn] Tian, Zhongzhen [verfasserIn] |
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E-Artikel |
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| Sprache: |
Englisch |
| Erschienen: |
2019 |
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| Schlagwörter: |
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Enthalten in: Chemical Research in Chinese Universities - Jilin University and The Editorial Department of Chemical Research in Chinese Universities, 2012, 35(2019), 5 vom: 06. Sept., Seite 799-805 |
|---|---|
| Übergeordnetes Werk: |
volume:35 ; year:2019 ; number:5 ; day:06 ; month:09 ; pages:799-805 |
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10.1007/s40242-019-9122-5 |
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| 520 | |a Abstract A series of novel 5-alkoxyfuran-2(5H)-one derivatives was synthesized, and characterized by 1H NMR, 13C NMR and HRMS. Biological activities of all the title compounds were evaluated systematically. Preliminary bioassays indicated that most of the compounds exhibited moderate insecticidal activities against Aphis craccivora and Nilaparvata lugens at 100 mg/L. Compounds 4h and 4w exhibited 100% mortality rate against Aphis craccivora at 100 mg/L, and compound h exhibited good mortality rate against Aphis craccivora and Nilaparvata lugens (60% and 75%, respectively) even at 4 mg/L. The results demonstrated the impact of various chemical groups on insecticidal activities and provided a potential clue for further exploring novel high-effective broad-spectrum insecticides. | ||
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10.1007/s40242-019-9122-5 doi (DE-627)SPR03292187X (SPR)s40242-019-9122-5-e DE-627 ger DE-627 rakwb eng Wang, Xianhao verfasserin aut Design, Synthesis and Insecticidal Activities of Novel 5-Alkoxyfuran-2(5H)-one Derivatives 2019 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Abstract A series of novel 5-alkoxyfuran-2(5H)-one derivatives was synthesized, and characterized by 1H NMR, 13C NMR and HRMS. Biological activities of all the title compounds were evaluated systematically. Preliminary bioassays indicated that most of the compounds exhibited moderate insecticidal activities against Aphis craccivora and Nilaparvata lugens at 100 mg/L. Compounds 4h and 4w exhibited 100% mortality rate against Aphis craccivora at 100 mg/L, and compound h exhibited good mortality rate against Aphis craccivora and Nilaparvata lugens (60% and 75%, respectively) even at 4 mg/L. The results demonstrated the impact of various chemical groups on insecticidal activities and provided a potential clue for further exploring novel high-effective broad-spectrum insecticides. Butenolide derivative (dpeaa)DE-He213 Flupyradifurone (dpeaa)DE-He213 Neonicotinoid (dpeaa)DE-He213 Insecticidal activity (dpeaa)DE-He213 Li, Jianguo verfasserin aut Wang, Guangjian verfasserin aut Han, Xianzheng verfasserin aut Li, Dongmei verfasserin aut Tian, Zhongzhen verfasserin aut Enthalten in Chemical Research in Chinese Universities Jilin University and The Editorial Department of Chemical Research in Chinese Universities, 2012 35(2019), 5 vom: 06. Sept., Seite 799-805 (DE-627)SPR03290777X nnns volume:35 year:2019 number:5 day:06 month:09 pages:799-805 https://dx.doi.org/10.1007/s40242-019-9122-5 lizenzpflichtig Volltext GBV_USEFLAG_A SYSFLAG_A GBV_SPRINGER SSG-OLC-PHA AR 35 2019 5 06 09 799-805 |
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10.1007/s40242-019-9122-5 doi (DE-627)SPR03292187X (SPR)s40242-019-9122-5-e DE-627 ger DE-627 rakwb eng Wang, Xianhao verfasserin aut Design, Synthesis and Insecticidal Activities of Novel 5-Alkoxyfuran-2(5H)-one Derivatives 2019 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Abstract A series of novel 5-alkoxyfuran-2(5H)-one derivatives was synthesized, and characterized by 1H NMR, 13C NMR and HRMS. Biological activities of all the title compounds were evaluated systematically. Preliminary bioassays indicated that most of the compounds exhibited moderate insecticidal activities against Aphis craccivora and Nilaparvata lugens at 100 mg/L. Compounds 4h and 4w exhibited 100% mortality rate against Aphis craccivora at 100 mg/L, and compound h exhibited good mortality rate against Aphis craccivora and Nilaparvata lugens (60% and 75%, respectively) even at 4 mg/L. The results demonstrated the impact of various chemical groups on insecticidal activities and provided a potential clue for further exploring novel high-effective broad-spectrum insecticides. Butenolide derivative (dpeaa)DE-He213 Flupyradifurone (dpeaa)DE-He213 Neonicotinoid (dpeaa)DE-He213 Insecticidal activity (dpeaa)DE-He213 Li, Jianguo verfasserin aut Wang, Guangjian verfasserin aut Han, Xianzheng verfasserin aut Li, Dongmei verfasserin aut Tian, Zhongzhen verfasserin aut Enthalten in Chemical Research in Chinese Universities Jilin University and The Editorial Department of Chemical Research in Chinese Universities, 2012 35(2019), 5 vom: 06. Sept., Seite 799-805 (DE-627)SPR03290777X nnns volume:35 year:2019 number:5 day:06 month:09 pages:799-805 https://dx.doi.org/10.1007/s40242-019-9122-5 lizenzpflichtig Volltext GBV_USEFLAG_A SYSFLAG_A GBV_SPRINGER SSG-OLC-PHA AR 35 2019 5 06 09 799-805 |
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10.1007/s40242-019-9122-5 doi (DE-627)SPR03292187X (SPR)s40242-019-9122-5-e DE-627 ger DE-627 rakwb eng Wang, Xianhao verfasserin aut Design, Synthesis and Insecticidal Activities of Novel 5-Alkoxyfuran-2(5H)-one Derivatives 2019 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Abstract A series of novel 5-alkoxyfuran-2(5H)-one derivatives was synthesized, and characterized by 1H NMR, 13C NMR and HRMS. Biological activities of all the title compounds were evaluated systematically. Preliminary bioassays indicated that most of the compounds exhibited moderate insecticidal activities against Aphis craccivora and Nilaparvata lugens at 100 mg/L. Compounds 4h and 4w exhibited 100% mortality rate against Aphis craccivora at 100 mg/L, and compound h exhibited good mortality rate against Aphis craccivora and Nilaparvata lugens (60% and 75%, respectively) even at 4 mg/L. The results demonstrated the impact of various chemical groups on insecticidal activities and provided a potential clue for further exploring novel high-effective broad-spectrum insecticides. Butenolide derivative (dpeaa)DE-He213 Flupyradifurone (dpeaa)DE-He213 Neonicotinoid (dpeaa)DE-He213 Insecticidal activity (dpeaa)DE-He213 Li, Jianguo verfasserin aut Wang, Guangjian verfasserin aut Han, Xianzheng verfasserin aut Li, Dongmei verfasserin aut Tian, Zhongzhen verfasserin aut Enthalten in Chemical Research in Chinese Universities Jilin University and The Editorial Department of Chemical Research in Chinese Universities, 2012 35(2019), 5 vom: 06. Sept., Seite 799-805 (DE-627)SPR03290777X nnns volume:35 year:2019 number:5 day:06 month:09 pages:799-805 https://dx.doi.org/10.1007/s40242-019-9122-5 lizenzpflichtig Volltext GBV_USEFLAG_A SYSFLAG_A GBV_SPRINGER SSG-OLC-PHA AR 35 2019 5 06 09 799-805 |
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10.1007/s40242-019-9122-5 doi (DE-627)SPR03292187X (SPR)s40242-019-9122-5-e DE-627 ger DE-627 rakwb eng Wang, Xianhao verfasserin aut Design, Synthesis and Insecticidal Activities of Novel 5-Alkoxyfuran-2(5H)-one Derivatives 2019 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Abstract A series of novel 5-alkoxyfuran-2(5H)-one derivatives was synthesized, and characterized by 1H NMR, 13C NMR and HRMS. Biological activities of all the title compounds were evaluated systematically. Preliminary bioassays indicated that most of the compounds exhibited moderate insecticidal activities against Aphis craccivora and Nilaparvata lugens at 100 mg/L. Compounds 4h and 4w exhibited 100% mortality rate against Aphis craccivora at 100 mg/L, and compound h exhibited good mortality rate against Aphis craccivora and Nilaparvata lugens (60% and 75%, respectively) even at 4 mg/L. The results demonstrated the impact of various chemical groups on insecticidal activities and provided a potential clue for further exploring novel high-effective broad-spectrum insecticides. Butenolide derivative (dpeaa)DE-He213 Flupyradifurone (dpeaa)DE-He213 Neonicotinoid (dpeaa)DE-He213 Insecticidal activity (dpeaa)DE-He213 Li, Jianguo verfasserin aut Wang, Guangjian verfasserin aut Han, Xianzheng verfasserin aut Li, Dongmei verfasserin aut Tian, Zhongzhen verfasserin aut Enthalten in Chemical Research in Chinese Universities Jilin University and The Editorial Department of Chemical Research in Chinese Universities, 2012 35(2019), 5 vom: 06. Sept., Seite 799-805 (DE-627)SPR03290777X nnns volume:35 year:2019 number:5 day:06 month:09 pages:799-805 https://dx.doi.org/10.1007/s40242-019-9122-5 lizenzpflichtig Volltext GBV_USEFLAG_A SYSFLAG_A GBV_SPRINGER SSG-OLC-PHA AR 35 2019 5 06 09 799-805 |
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10.1007/s40242-019-9122-5 doi (DE-627)SPR03292187X (SPR)s40242-019-9122-5-e DE-627 ger DE-627 rakwb eng Wang, Xianhao verfasserin aut Design, Synthesis and Insecticidal Activities of Novel 5-Alkoxyfuran-2(5H)-one Derivatives 2019 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Abstract A series of novel 5-alkoxyfuran-2(5H)-one derivatives was synthesized, and characterized by 1H NMR, 13C NMR and HRMS. Biological activities of all the title compounds were evaluated systematically. Preliminary bioassays indicated that most of the compounds exhibited moderate insecticidal activities against Aphis craccivora and Nilaparvata lugens at 100 mg/L. Compounds 4h and 4w exhibited 100% mortality rate against Aphis craccivora at 100 mg/L, and compound h exhibited good mortality rate against Aphis craccivora and Nilaparvata lugens (60% and 75%, respectively) even at 4 mg/L. The results demonstrated the impact of various chemical groups on insecticidal activities and provided a potential clue for further exploring novel high-effective broad-spectrum insecticides. Butenolide derivative (dpeaa)DE-He213 Flupyradifurone (dpeaa)DE-He213 Neonicotinoid (dpeaa)DE-He213 Insecticidal activity (dpeaa)DE-He213 Li, Jianguo verfasserin aut Wang, Guangjian verfasserin aut Han, Xianzheng verfasserin aut Li, Dongmei verfasserin aut Tian, Zhongzhen verfasserin aut Enthalten in Chemical Research in Chinese Universities Jilin University and The Editorial Department of Chemical Research in Chinese Universities, 2012 35(2019), 5 vom: 06. Sept., Seite 799-805 (DE-627)SPR03290777X nnns volume:35 year:2019 number:5 day:06 month:09 pages:799-805 https://dx.doi.org/10.1007/s40242-019-9122-5 lizenzpflichtig Volltext GBV_USEFLAG_A SYSFLAG_A GBV_SPRINGER SSG-OLC-PHA AR 35 2019 5 06 09 799-805 |
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Design, Synthesis and Insecticidal Activities of Novel 5-Alkoxyfuran-2(5H)-one Derivatives |
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Abstract A series of novel 5-alkoxyfuran-2(5H)-one derivatives was synthesized, and characterized by 1H NMR, 13C NMR and HRMS. Biological activities of all the title compounds were evaluated systematically. Preliminary bioassays indicated that most of the compounds exhibited moderate insecticidal activities against Aphis craccivora and Nilaparvata lugens at 100 mg/L. Compounds 4h and 4w exhibited 100% mortality rate against Aphis craccivora at 100 mg/L, and compound h exhibited good mortality rate against Aphis craccivora and Nilaparvata lugens (60% and 75%, respectively) even at 4 mg/L. The results demonstrated the impact of various chemical groups on insecticidal activities and provided a potential clue for further exploring novel high-effective broad-spectrum insecticides. |
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Abstract A series of novel 5-alkoxyfuran-2(5H)-one derivatives was synthesized, and characterized by 1H NMR, 13C NMR and HRMS. Biological activities of all the title compounds were evaluated systematically. Preliminary bioassays indicated that most of the compounds exhibited moderate insecticidal activities against Aphis craccivora and Nilaparvata lugens at 100 mg/L. Compounds 4h and 4w exhibited 100% mortality rate against Aphis craccivora at 100 mg/L, and compound h exhibited good mortality rate against Aphis craccivora and Nilaparvata lugens (60% and 75%, respectively) even at 4 mg/L. The results demonstrated the impact of various chemical groups on insecticidal activities and provided a potential clue for further exploring novel high-effective broad-spectrum insecticides. |
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Abstract A series of novel 5-alkoxyfuran-2(5H)-one derivatives was synthesized, and characterized by 1H NMR, 13C NMR and HRMS. Biological activities of all the title compounds were evaluated systematically. Preliminary bioassays indicated that most of the compounds exhibited moderate insecticidal activities against Aphis craccivora and Nilaparvata lugens at 100 mg/L. Compounds 4h and 4w exhibited 100% mortality rate against Aphis craccivora at 100 mg/L, and compound h exhibited good mortality rate against Aphis craccivora and Nilaparvata lugens (60% and 75%, respectively) even at 4 mg/L. The results demonstrated the impact of various chemical groups on insecticidal activities and provided a potential clue for further exploring novel high-effective broad-spectrum insecticides. |
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Design, Synthesis and Insecticidal Activities of Novel 5-Alkoxyfuran-2(5H)-one Derivatives |
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https://dx.doi.org/10.1007/s40242-019-9122-5 |
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Li, Jianguo Wang, Guangjian Han, Xianzheng Li, Dongmei Tian, Zhongzhen |
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Li, Jianguo Wang, Guangjian Han, Xianzheng Li, Dongmei Tian, Zhongzhen |
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2024-07-03T15:28:05.342Z |
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