Radium-223 Chloride

Abstract In the last few years, the treatment of castration-resistant prostate carcinoma (CRPC) has changed completely. The approval of docetaxel and subsequent investigation in this field have led to development of new agents that have demonstrated an improvement in overall survival in the post-doc...
Ausführliche Beschreibung

Gespeichert in:

Autor*in:	Pinto, Álvaro [verfasserIn] Cruz, Patricia [verfasserIn]

Format:	E-Artikel
Sprache:	Englisch

Erschienen:	2012

Schlagwörter:	Overall Survival Docetaxel Zoledronic Acid Denosumab Abiraterone

Übergeordnetes Werk:	Enthalten in: Drugs in R & D - [S.l.] : Springer International, 1999, 12(2012), 4 vom: Dez., Seite 227-233
Übergeordnetes Werk:	volume:12 ; year:2012 ; number:4 ; month:12 ; pages:227-233

Links:	Volltext

DOI / URN:	10.2165/11636250-000000000-00000

Katalog-ID:	SPR033293910

Internformat


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520			\|a Abstract In the last few years, the treatment of castration-resistant prostate carcinoma (CRPC) has changed completely. The approval of docetaxel and subsequent investigation in this field have led to development of new agents that have demonstrated an improvement in overall survival in the post-docetaxel setting, such as cabazitaxel and abiraterone. Radium-223 chloride is a radioisotope that has recently shown efficacy after docetaxel and in patients unfit for docetaxel, with improvements in overall survival and the time to the first skeletal-related event, compared with placebo, without increasing toxicity. These findings have made this agent a new option for treatment of these patients in the near future.
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Indexfelder

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matchkey_str	article:11796901:2012----::aim2cl
hierarchy_sort_str	2012
bklnumber	44.40
publishDate	2012
allfields	10.2165/11636250-000000000-00000 doi (DE-627)SPR033293910 (SPR)11636250-000000000-00000-e DE-627 ger DE-627 rakwb eng 610 ASE 44.40 bkl Pinto, Álvaro verfasserin aut Radium-223 Chloride 2012 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Abstract In the last few years, the treatment of castration-resistant prostate carcinoma (CRPC) has changed completely. The approval of docetaxel and subsequent investigation in this field have led to development of new agents that have demonstrated an improvement in overall survival in the post-docetaxel setting, such as cabazitaxel and abiraterone. Radium-223 chloride is a radioisotope that has recently shown efficacy after docetaxel and in patients unfit for docetaxel, with improvements in overall survival and the time to the first skeletal-related event, compared with placebo, without increasing toxicity. These findings have made this agent a new option for treatment of these patients in the near future. Overall Survival (dpeaa)DE-He213 Docetaxel (dpeaa)DE-He213 Zoledronic Acid (dpeaa)DE-He213 Denosumab (dpeaa)DE-He213 Abiraterone (dpeaa)DE-He213 Cruz, Patricia verfasserin aut Enthalten in Drugs in R & D [S.l.] : Springer International, 1999 12(2012), 4 vom: Dez., Seite 227-233 (DE-627)357171527 (DE-600)2094513-9 1179-6901 nnns volume:12 year:2012 number:4 month:12 pages:227-233 https://dx.doi.org/10.2165/11636250-000000000-00000 kostenfrei Volltext GBV_USEFLAG_A SYSFLAG_A GBV_SPRINGER SSG-OLC-PHA SSG-OPC-PHA SSG-OPC-ASE GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_702 GBV_ILN_2001 GBV_ILN_2003 GBV_ILN_2005 GBV_ILN_2006 GBV_ILN_2008 GBV_ILN_2009 GBV_ILN_2010 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2015 GBV_ILN_2020 GBV_ILN_2021 GBV_ILN_2025 GBV_ILN_2031 GBV_ILN_2044 GBV_ILN_2048 GBV_ILN_2050 GBV_ILN_2055 GBV_ILN_2056 GBV_ILN_2057 GBV_ILN_2061 GBV_ILN_2111 GBV_ILN_2153 GBV_ILN_2190 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 44.40 ASE AR 12 2012 4 12 227-233
spelling	10.2165/11636250-000000000-00000 doi (DE-627)SPR033293910 (SPR)11636250-000000000-00000-e DE-627 ger DE-627 rakwb eng 610 ASE 44.40 bkl Pinto, Álvaro verfasserin aut Radium-223 Chloride 2012 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Abstract In the last few years, the treatment of castration-resistant prostate carcinoma (CRPC) has changed completely. The approval of docetaxel and subsequent investigation in this field have led to development of new agents that have demonstrated an improvement in overall survival in the post-docetaxel setting, such as cabazitaxel and abiraterone. Radium-223 chloride is a radioisotope that has recently shown efficacy after docetaxel and in patients unfit for docetaxel, with improvements in overall survival and the time to the first skeletal-related event, compared with placebo, without increasing toxicity. These findings have made this agent a new option for treatment of these patients in the near future. Overall Survival (dpeaa)DE-He213 Docetaxel (dpeaa)DE-He213 Zoledronic Acid (dpeaa)DE-He213 Denosumab (dpeaa)DE-He213 Abiraterone (dpeaa)DE-He213 Cruz, Patricia verfasserin aut Enthalten in Drugs in R & D [S.l.] : Springer International, 1999 12(2012), 4 vom: Dez., Seite 227-233 (DE-627)357171527 (DE-600)2094513-9 1179-6901 nnns volume:12 year:2012 number:4 month:12 pages:227-233 https://dx.doi.org/10.2165/11636250-000000000-00000 kostenfrei Volltext GBV_USEFLAG_A SYSFLAG_A GBV_SPRINGER SSG-OLC-PHA SSG-OPC-PHA SSG-OPC-ASE GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_702 GBV_ILN_2001 GBV_ILN_2003 GBV_ILN_2005 GBV_ILN_2006 GBV_ILN_2008 GBV_ILN_2009 GBV_ILN_2010 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2015 GBV_ILN_2020 GBV_ILN_2021 GBV_ILN_2025 GBV_ILN_2031 GBV_ILN_2044 GBV_ILN_2048 GBV_ILN_2050 GBV_ILN_2055 GBV_ILN_2056 GBV_ILN_2057 GBV_ILN_2061 GBV_ILN_2111 GBV_ILN_2153 GBV_ILN_2190 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 44.40 ASE AR 12 2012 4 12 227-233
allfields_unstemmed	10.2165/11636250-000000000-00000 doi (DE-627)SPR033293910 (SPR)11636250-000000000-00000-e DE-627 ger DE-627 rakwb eng 610 ASE 44.40 bkl Pinto, Álvaro verfasserin aut Radium-223 Chloride 2012 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Abstract In the last few years, the treatment of castration-resistant prostate carcinoma (CRPC) has changed completely. The approval of docetaxel and subsequent investigation in this field have led to development of new agents that have demonstrated an improvement in overall survival in the post-docetaxel setting, such as cabazitaxel and abiraterone. Radium-223 chloride is a radioisotope that has recently shown efficacy after docetaxel and in patients unfit for docetaxel, with improvements in overall survival and the time to the first skeletal-related event, compared with placebo, without increasing toxicity. These findings have made this agent a new option for treatment of these patients in the near future. Overall Survival (dpeaa)DE-He213 Docetaxel (dpeaa)DE-He213 Zoledronic Acid (dpeaa)DE-He213 Denosumab (dpeaa)DE-He213 Abiraterone (dpeaa)DE-He213 Cruz, Patricia verfasserin aut Enthalten in Drugs in R & D [S.l.] : Springer International, 1999 12(2012), 4 vom: Dez., Seite 227-233 (DE-627)357171527 (DE-600)2094513-9 1179-6901 nnns volume:12 year:2012 number:4 month:12 pages:227-233 https://dx.doi.org/10.2165/11636250-000000000-00000 kostenfrei Volltext GBV_USEFLAG_A SYSFLAG_A GBV_SPRINGER SSG-OLC-PHA SSG-OPC-PHA SSG-OPC-ASE GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_702 GBV_ILN_2001 GBV_ILN_2003 GBV_ILN_2005 GBV_ILN_2006 GBV_ILN_2008 GBV_ILN_2009 GBV_ILN_2010 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2015 GBV_ILN_2020 GBV_ILN_2021 GBV_ILN_2025 GBV_ILN_2031 GBV_ILN_2044 GBV_ILN_2048 GBV_ILN_2050 GBV_ILN_2055 GBV_ILN_2056 GBV_ILN_2057 GBV_ILN_2061 GBV_ILN_2111 GBV_ILN_2153 GBV_ILN_2190 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 44.40 ASE AR 12 2012 4 12 227-233
allfieldsGer	10.2165/11636250-000000000-00000 doi (DE-627)SPR033293910 (SPR)11636250-000000000-00000-e DE-627 ger DE-627 rakwb eng 610 ASE 44.40 bkl Pinto, Álvaro verfasserin aut Radium-223 Chloride 2012 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Abstract In the last few years, the treatment of castration-resistant prostate carcinoma (CRPC) has changed completely. The approval of docetaxel and subsequent investigation in this field have led to development of new agents that have demonstrated an improvement in overall survival in the post-docetaxel setting, such as cabazitaxel and abiraterone. Radium-223 chloride is a radioisotope that has recently shown efficacy after docetaxel and in patients unfit for docetaxel, with improvements in overall survival and the time to the first skeletal-related event, compared with placebo, without increasing toxicity. These findings have made this agent a new option for treatment of these patients in the near future. Overall Survival (dpeaa)DE-He213 Docetaxel (dpeaa)DE-He213 Zoledronic Acid (dpeaa)DE-He213 Denosumab (dpeaa)DE-He213 Abiraterone (dpeaa)DE-He213 Cruz, Patricia verfasserin aut Enthalten in Drugs in R & D [S.l.] : Springer International, 1999 12(2012), 4 vom: Dez., Seite 227-233 (DE-627)357171527 (DE-600)2094513-9 1179-6901 nnns volume:12 year:2012 number:4 month:12 pages:227-233 https://dx.doi.org/10.2165/11636250-000000000-00000 kostenfrei Volltext GBV_USEFLAG_A SYSFLAG_A GBV_SPRINGER SSG-OLC-PHA SSG-OPC-PHA SSG-OPC-ASE GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_702 GBV_ILN_2001 GBV_ILN_2003 GBV_ILN_2005 GBV_ILN_2006 GBV_ILN_2008 GBV_ILN_2009 GBV_ILN_2010 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2015 GBV_ILN_2020 GBV_ILN_2021 GBV_ILN_2025 GBV_ILN_2031 GBV_ILN_2044 GBV_ILN_2048 GBV_ILN_2050 GBV_ILN_2055 GBV_ILN_2056 GBV_ILN_2057 GBV_ILN_2061 GBV_ILN_2111 GBV_ILN_2153 GBV_ILN_2190 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 44.40 ASE AR 12 2012 4 12 227-233
allfieldsSound	10.2165/11636250-000000000-00000 doi (DE-627)SPR033293910 (SPR)11636250-000000000-00000-e DE-627 ger DE-627 rakwb eng 610 ASE 44.40 bkl Pinto, Álvaro verfasserin aut Radium-223 Chloride 2012 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Abstract In the last few years, the treatment of castration-resistant prostate carcinoma (CRPC) has changed completely. The approval of docetaxel and subsequent investigation in this field have led to development of new agents that have demonstrated an improvement in overall survival in the post-docetaxel setting, such as cabazitaxel and abiraterone. Radium-223 chloride is a radioisotope that has recently shown efficacy after docetaxel and in patients unfit for docetaxel, with improvements in overall survival and the time to the first skeletal-related event, compared with placebo, without increasing toxicity. These findings have made this agent a new option for treatment of these patients in the near future. Overall Survival (dpeaa)DE-He213 Docetaxel (dpeaa)DE-He213 Zoledronic Acid (dpeaa)DE-He213 Denosumab (dpeaa)DE-He213 Abiraterone (dpeaa)DE-He213 Cruz, Patricia verfasserin aut Enthalten in Drugs in R & D [S.l.] : Springer International, 1999 12(2012), 4 vom: Dez., Seite 227-233 (DE-627)357171527 (DE-600)2094513-9 1179-6901 nnns volume:12 year:2012 number:4 month:12 pages:227-233 https://dx.doi.org/10.2165/11636250-000000000-00000 kostenfrei Volltext GBV_USEFLAG_A SYSFLAG_A GBV_SPRINGER SSG-OLC-PHA SSG-OPC-PHA SSG-OPC-ASE GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_702 GBV_ILN_2001 GBV_ILN_2003 GBV_ILN_2005 GBV_ILN_2006 GBV_ILN_2008 GBV_ILN_2009 GBV_ILN_2010 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2015 GBV_ILN_2020 GBV_ILN_2021 GBV_ILN_2025 GBV_ILN_2031 GBV_ILN_2044 GBV_ILN_2048 GBV_ILN_2050 GBV_ILN_2055 GBV_ILN_2056 GBV_ILN_2057 GBV_ILN_2061 GBV_ILN_2111 GBV_ILN_2153 GBV_ILN_2190 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 44.40 ASE AR 12 2012 4 12 227-233
language	English
source	Enthalten in Drugs in R & D 12(2012), 4 vom: Dez., Seite 227-233 volume:12 year:2012 number:4 month:12 pages:227-233
sourceStr	Enthalten in Drugs in R & D 12(2012), 4 vom: Dez., Seite 227-233 volume:12 year:2012 number:4 month:12 pages:227-233
format_phy_str_mv	Article
institution	findex.gbv.de
topic_facet	Overall Survival Docetaxel Zoledronic Acid Denosumab Abiraterone
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container_title	Drugs in R & D
authorswithroles_txt_mv	Pinto, Álvaro @@aut@@ Cruz, Patricia @@aut@@
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author	Pinto, Álvaro
spellingShingle	Pinto, Álvaro ddc 610 bkl 44.40 misc Overall Survival misc Docetaxel misc Zoledronic Acid misc Denosumab misc Abiraterone Radium-223 Chloride
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topic_title	610 ASE 44.40 bkl Radium-223 Chloride Overall Survival (dpeaa)DE-He213 Docetaxel (dpeaa)DE-He213 Zoledronic Acid (dpeaa)DE-He213 Denosumab (dpeaa)DE-He213 Abiraterone (dpeaa)DE-He213
topic	ddc 610 bkl 44.40 misc Overall Survival misc Docetaxel misc Zoledronic Acid misc Denosumab misc Abiraterone
topic_unstemmed	ddc 610 bkl 44.40 misc Overall Survival misc Docetaxel misc Zoledronic Acid misc Denosumab misc Abiraterone
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title	Radium-223 Chloride
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title_full	Radium-223 Chloride
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title_sort	radium-223 chloride
title_auth	Radium-223 Chloride
abstract	Abstract In the last few years, the treatment of castration-resistant prostate carcinoma (CRPC) has changed completely. The approval of docetaxel and subsequent investigation in this field have led to development of new agents that have demonstrated an improvement in overall survival in the post-docetaxel setting, such as cabazitaxel and abiraterone. Radium-223 chloride is a radioisotope that has recently shown efficacy after docetaxel and in patients unfit for docetaxel, with improvements in overall survival and the time to the first skeletal-related event, compared with placebo, without increasing toxicity. These findings have made this agent a new option for treatment of these patients in the near future.
abstractGer	Abstract In the last few years, the treatment of castration-resistant prostate carcinoma (CRPC) has changed completely. The approval of docetaxel and subsequent investigation in this field have led to development of new agents that have demonstrated an improvement in overall survival in the post-docetaxel setting, such as cabazitaxel and abiraterone. Radium-223 chloride is a radioisotope that has recently shown efficacy after docetaxel and in patients unfit for docetaxel, with improvements in overall survival and the time to the first skeletal-related event, compared with placebo, without increasing toxicity. These findings have made this agent a new option for treatment of these patients in the near future.
abstract_unstemmed	Abstract In the last few years, the treatment of castration-resistant prostate carcinoma (CRPC) has changed completely. The approval of docetaxel and subsequent investigation in this field have led to development of new agents that have demonstrated an improvement in overall survival in the post-docetaxel setting, such as cabazitaxel and abiraterone. Radium-223 chloride is a radioisotope that has recently shown efficacy after docetaxel and in patients unfit for docetaxel, with improvements in overall survival and the time to the first skeletal-related event, compared with placebo, without increasing toxicity. These findings have made this agent a new option for treatment of these patients in the near future.
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title_short	Radium-223 Chloride
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up_date	2024-07-03T17:46:12.661Z
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