The risk of osteoporotic fractures and its associating risk factors according to the FRAX model in the Iranian patients: a follow-up cohort

Background The present study is designed to assess the incidence rate of osteoporotic fracture and its risk factors, particularly those used to predict the 10-year risk of osteoporotic fracture in FRAX based on the data gathered through a follow up cohort initiated in 2000. Methods The present retro...
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Autor*in:	Ghafoori, Shahnaz [verfasserIn] Keshtkar, Abbasali Khashayar, Patricia Ebrahimi, Mehdi Ramezani, Majid Mohammadi, Zahra Saeidifard, Farzane Nemati, Nasrin Khoshbin, Maryam Azizian, Solmaz Zare, Fatemeh Shirazi, Sara Larijani, Bagher

Format:	E-Artikel
Sprache:	Englisch

Erschienen:	2014

Schlagwörter:	Fracture FRAX Major osteoporotic fracture

Anmerkung:	© Ghafoori et al.; licensee BioMed Central Ltd. 2014

Übergeordnetes Werk:	Enthalten in: Journal of diabetes & metabolic disorders - London : BioMed Centra, 2012, 13(2014), 1 vom: 22. Okt.
Übergeordnetes Werk:	volume:13 ; year:2014 ; number:1 ; day:22 ; month:10

Links:	Volltext

DOI / URN:	10.1186/s40200-014-0093-2

Katalog-ID:	SPR033841772

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520			\|a Background The present study is designed to assess the incidence rate of osteoporotic fracture and its risk factors, particularly those used to predict the 10-year risk of osteoporotic fracture in FRAX based on the data gathered through a follow up cohort initiated in 2000. Methods The present retrospective cohort was conducted on men and women from 40 to 90 years of age enrolled in the IROSTEOPs study. A phone survey was conducted during 2013 and beginning of 2014 to assess the fractures (traumatic/osteoporotic) occurring at the time of inclusion until the date of the telephone survey, its type and mechanism, and the patient’s age at the time of accident. Survival analysis using Kaplan-Meier product-limit method was performed with the time of fracture as the study outcome. Results Final study population consisted of 1233 individuals, translated in to 9133 person years. The incidence rate of osteoporotic fracture was reported to be 359.1 cases in every 10,000 person years. The 10-year Kaplan-Meier estimate of any kind of major osteoporotic fractures for all the subcohort population was 10.75%. Osteoporosis (HR = 0.75), Discordance between femoral neck and spine (HR = 1.45), Diabetes (HR = 1.81), IBD (HR = 1.84), immobility more than 90 days (HR = 2.19), and personal history of fracture (HR = 7.75) had a considerable effect on the 10-year risk of major osteoporotic fractures. Conclusions Adding new clinical risk factors to FRAX® may help improve fracture prediction in the Iranian population.
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allfields	10.1186/s40200-014-0093-2 doi (DE-627)SPR033841772 (SPR)s40200-014-0093-2-e DE-627 ger DE-627 rakwb eng Ghafoori, Shahnaz verfasserin aut The risk of osteoporotic fractures and its associating risk factors according to the FRAX model in the Iranian patients: a follow-up cohort 2014 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier © Ghafoori et al.; licensee BioMed Central Ltd. 2014 Background The present study is designed to assess the incidence rate of osteoporotic fracture and its risk factors, particularly those used to predict the 10-year risk of osteoporotic fracture in FRAX based on the data gathered through a follow up cohort initiated in 2000. Methods The present retrospective cohort was conducted on men and women from 40 to 90 years of age enrolled in the IROSTEOPs study. A phone survey was conducted during 2013 and beginning of 2014 to assess the fractures (traumatic/osteoporotic) occurring at the time of inclusion until the date of the telephone survey, its type and mechanism, and the patient’s age at the time of accident. Survival analysis using Kaplan-Meier product-limit method was performed with the time of fracture as the study outcome. Results Final study population consisted of 1233 individuals, translated in to 9133 person years. The incidence rate of osteoporotic fracture was reported to be 359.1 cases in every 10,000 person years. The 10-year Kaplan-Meier estimate of any kind of major osteoporotic fractures for all the subcohort population was 10.75%. Osteoporosis (HR = 0.75), Discordance between femoral neck and spine (HR = 1.45), Diabetes (HR = 1.81), IBD (HR = 1.84), immobility more than 90 days (HR = 2.19), and personal history of fracture (HR = 7.75) had a considerable effect on the 10-year risk of major osteoporotic fractures. Conclusions Adding new clinical risk factors to FRAX® may help improve fracture prediction in the Iranian population. Fracture (dpeaa)DE-He213 FRAX (dpeaa)DE-He213 Major osteoporotic fracture (dpeaa)DE-He213 Keshtkar, Abbasali aut Khashayar, Patricia aut Ebrahimi, Mehdi aut Ramezani, Majid aut Mohammadi, Zahra aut Saeidifard, Farzane aut Nemati, Nasrin aut Khoshbin, Maryam aut Azizian, Solmaz aut Zare, Fatemeh aut Shirazi, Sara aut Larijani, Bagher aut Enthalten in Journal of diabetes & metabolic disorders London : BioMed Centra, 2012 13(2014), 1 vom: 22. Okt. (DE-627)723900051 (DE-600)2680289-2 2251-6581 nnns volume:13 year:2014 number:1 day:22 month:10 https://dx.doi.org/10.1186/s40200-014-0093-2 kostenfrei Volltext GBV_USEFLAG_A SYSFLAG_A GBV_SPRINGER SSG-OLC-PHA GBV_ILN_11 GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_2003 GBV_ILN_2014 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 13 2014 1 22 10
spelling	10.1186/s40200-014-0093-2 doi (DE-627)SPR033841772 (SPR)s40200-014-0093-2-e DE-627 ger DE-627 rakwb eng Ghafoori, Shahnaz verfasserin aut The risk of osteoporotic fractures and its associating risk factors according to the FRAX model in the Iranian patients: a follow-up cohort 2014 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier © Ghafoori et al.; licensee BioMed Central Ltd. 2014 Background The present study is designed to assess the incidence rate of osteoporotic fracture and its risk factors, particularly those used to predict the 10-year risk of osteoporotic fracture in FRAX based on the data gathered through a follow up cohort initiated in 2000. Methods The present retrospective cohort was conducted on men and women from 40 to 90 years of age enrolled in the IROSTEOPs study. A phone survey was conducted during 2013 and beginning of 2014 to assess the fractures (traumatic/osteoporotic) occurring at the time of inclusion until the date of the telephone survey, its type and mechanism, and the patient’s age at the time of accident. Survival analysis using Kaplan-Meier product-limit method was performed with the time of fracture as the study outcome. Results Final study population consisted of 1233 individuals, translated in to 9133 person years. The incidence rate of osteoporotic fracture was reported to be 359.1 cases in every 10,000 person years. The 10-year Kaplan-Meier estimate of any kind of major osteoporotic fractures for all the subcohort population was 10.75%. Osteoporosis (HR = 0.75), Discordance between femoral neck and spine (HR = 1.45), Diabetes (HR = 1.81), IBD (HR = 1.84), immobility more than 90 days (HR = 2.19), and personal history of fracture (HR = 7.75) had a considerable effect on the 10-year risk of major osteoporotic fractures. Conclusions Adding new clinical risk factors to FRAX® may help improve fracture prediction in the Iranian population. Fracture (dpeaa)DE-He213 FRAX (dpeaa)DE-He213 Major osteoporotic fracture (dpeaa)DE-He213 Keshtkar, Abbasali aut Khashayar, Patricia aut Ebrahimi, Mehdi aut Ramezani, Majid aut Mohammadi, Zahra aut Saeidifard, Farzane aut Nemati, Nasrin aut Khoshbin, Maryam aut Azizian, Solmaz aut Zare, Fatemeh aut Shirazi, Sara aut Larijani, Bagher aut Enthalten in Journal of diabetes & metabolic disorders London : BioMed Centra, 2012 13(2014), 1 vom: 22. Okt. (DE-627)723900051 (DE-600)2680289-2 2251-6581 nnns volume:13 year:2014 number:1 day:22 month:10 https://dx.doi.org/10.1186/s40200-014-0093-2 kostenfrei Volltext GBV_USEFLAG_A SYSFLAG_A GBV_SPRINGER SSG-OLC-PHA GBV_ILN_11 GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_2003 GBV_ILN_2014 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 13 2014 1 22 10
allfields_unstemmed	10.1186/s40200-014-0093-2 doi (DE-627)SPR033841772 (SPR)s40200-014-0093-2-e DE-627 ger DE-627 rakwb eng Ghafoori, Shahnaz verfasserin aut The risk of osteoporotic fractures and its associating risk factors according to the FRAX model in the Iranian patients: a follow-up cohort 2014 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier © Ghafoori et al.; licensee BioMed Central Ltd. 2014 Background The present study is designed to assess the incidence rate of osteoporotic fracture and its risk factors, particularly those used to predict the 10-year risk of osteoporotic fracture in FRAX based on the data gathered through a follow up cohort initiated in 2000. Methods The present retrospective cohort was conducted on men and women from 40 to 90 years of age enrolled in the IROSTEOPs study. A phone survey was conducted during 2013 and beginning of 2014 to assess the fractures (traumatic/osteoporotic) occurring at the time of inclusion until the date of the telephone survey, its type and mechanism, and the patient’s age at the time of accident. Survival analysis using Kaplan-Meier product-limit method was performed with the time of fracture as the study outcome. Results Final study population consisted of 1233 individuals, translated in to 9133 person years. The incidence rate of osteoporotic fracture was reported to be 359.1 cases in every 10,000 person years. The 10-year Kaplan-Meier estimate of any kind of major osteoporotic fractures for all the subcohort population was 10.75%. Osteoporosis (HR = 0.75), Discordance between femoral neck and spine (HR = 1.45), Diabetes (HR = 1.81), IBD (HR = 1.84), immobility more than 90 days (HR = 2.19), and personal history of fracture (HR = 7.75) had a considerable effect on the 10-year risk of major osteoporotic fractures. Conclusions Adding new clinical risk factors to FRAX® may help improve fracture prediction in the Iranian population. Fracture (dpeaa)DE-He213 FRAX (dpeaa)DE-He213 Major osteoporotic fracture (dpeaa)DE-He213 Keshtkar, Abbasali aut Khashayar, Patricia aut Ebrahimi, Mehdi aut Ramezani, Majid aut Mohammadi, Zahra aut Saeidifard, Farzane aut Nemati, Nasrin aut Khoshbin, Maryam aut Azizian, Solmaz aut Zare, Fatemeh aut Shirazi, Sara aut Larijani, Bagher aut Enthalten in Journal of diabetes & metabolic disorders London : BioMed Centra, 2012 13(2014), 1 vom: 22. Okt. (DE-627)723900051 (DE-600)2680289-2 2251-6581 nnns volume:13 year:2014 number:1 day:22 month:10 https://dx.doi.org/10.1186/s40200-014-0093-2 kostenfrei Volltext GBV_USEFLAG_A SYSFLAG_A GBV_SPRINGER SSG-OLC-PHA GBV_ILN_11 GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_2003 GBV_ILN_2014 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 13 2014 1 22 10
allfieldsGer	10.1186/s40200-014-0093-2 doi (DE-627)SPR033841772 (SPR)s40200-014-0093-2-e DE-627 ger DE-627 rakwb eng Ghafoori, Shahnaz verfasserin aut The risk of osteoporotic fractures and its associating risk factors according to the FRAX model in the Iranian patients: a follow-up cohort 2014 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier © Ghafoori et al.; licensee BioMed Central Ltd. 2014 Background The present study is designed to assess the incidence rate of osteoporotic fracture and its risk factors, particularly those used to predict the 10-year risk of osteoporotic fracture in FRAX based on the data gathered through a follow up cohort initiated in 2000. Methods The present retrospective cohort was conducted on men and women from 40 to 90 years of age enrolled in the IROSTEOPs study. A phone survey was conducted during 2013 and beginning of 2014 to assess the fractures (traumatic/osteoporotic) occurring at the time of inclusion until the date of the telephone survey, its type and mechanism, and the patient’s age at the time of accident. Survival analysis using Kaplan-Meier product-limit method was performed with the time of fracture as the study outcome. Results Final study population consisted of 1233 individuals, translated in to 9133 person years. The incidence rate of osteoporotic fracture was reported to be 359.1 cases in every 10,000 person years. The 10-year Kaplan-Meier estimate of any kind of major osteoporotic fractures for all the subcohort population was 10.75%. Osteoporosis (HR = 0.75), Discordance between femoral neck and spine (HR = 1.45), Diabetes (HR = 1.81), IBD (HR = 1.84), immobility more than 90 days (HR = 2.19), and personal history of fracture (HR = 7.75) had a considerable effect on the 10-year risk of major osteoporotic fractures. Conclusions Adding new clinical risk factors to FRAX® may help improve fracture prediction in the Iranian population. Fracture (dpeaa)DE-He213 FRAX (dpeaa)DE-He213 Major osteoporotic fracture (dpeaa)DE-He213 Keshtkar, Abbasali aut Khashayar, Patricia aut Ebrahimi, Mehdi aut Ramezani, Majid aut Mohammadi, Zahra aut Saeidifard, Farzane aut Nemati, Nasrin aut Khoshbin, Maryam aut Azizian, Solmaz aut Zare, Fatemeh aut Shirazi, Sara aut Larijani, Bagher aut Enthalten in Journal of diabetes & metabolic disorders London : BioMed Centra, 2012 13(2014), 1 vom: 22. Okt. (DE-627)723900051 (DE-600)2680289-2 2251-6581 nnns volume:13 year:2014 number:1 day:22 month:10 https://dx.doi.org/10.1186/s40200-014-0093-2 kostenfrei Volltext GBV_USEFLAG_A SYSFLAG_A GBV_SPRINGER SSG-OLC-PHA GBV_ILN_11 GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_2003 GBV_ILN_2014 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 13 2014 1 22 10
allfieldsSound	10.1186/s40200-014-0093-2 doi (DE-627)SPR033841772 (SPR)s40200-014-0093-2-e DE-627 ger DE-627 rakwb eng Ghafoori, Shahnaz verfasserin aut The risk of osteoporotic fractures and its associating risk factors according to the FRAX model in the Iranian patients: a follow-up cohort 2014 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier © Ghafoori et al.; licensee BioMed Central Ltd. 2014 Background The present study is designed to assess the incidence rate of osteoporotic fracture and its risk factors, particularly those used to predict the 10-year risk of osteoporotic fracture in FRAX based on the data gathered through a follow up cohort initiated in 2000. Methods The present retrospective cohort was conducted on men and women from 40 to 90 years of age enrolled in the IROSTEOPs study. A phone survey was conducted during 2013 and beginning of 2014 to assess the fractures (traumatic/osteoporotic) occurring at the time of inclusion until the date of the telephone survey, its type and mechanism, and the patient’s age at the time of accident. Survival analysis using Kaplan-Meier product-limit method was performed with the time of fracture as the study outcome. Results Final study population consisted of 1233 individuals, translated in to 9133 person years. The incidence rate of osteoporotic fracture was reported to be 359.1 cases in every 10,000 person years. The 10-year Kaplan-Meier estimate of any kind of major osteoporotic fractures for all the subcohort population was 10.75%. Osteoporosis (HR = 0.75), Discordance between femoral neck and spine (HR = 1.45), Diabetes (HR = 1.81), IBD (HR = 1.84), immobility more than 90 days (HR = 2.19), and personal history of fracture (HR = 7.75) had a considerable effect on the 10-year risk of major osteoporotic fractures. Conclusions Adding new clinical risk factors to FRAX® may help improve fracture prediction in the Iranian population. Fracture (dpeaa)DE-He213 FRAX (dpeaa)DE-He213 Major osteoporotic fracture (dpeaa)DE-He213 Keshtkar, Abbasali aut Khashayar, Patricia aut Ebrahimi, Mehdi aut Ramezani, Majid aut Mohammadi, Zahra aut Saeidifard, Farzane aut Nemati, Nasrin aut Khoshbin, Maryam aut Azizian, Solmaz aut Zare, Fatemeh aut Shirazi, Sara aut Larijani, Bagher aut Enthalten in Journal of diabetes & metabolic disorders London : BioMed Centra, 2012 13(2014), 1 vom: 22. Okt. (DE-627)723900051 (DE-600)2680289-2 2251-6581 nnns volume:13 year:2014 number:1 day:22 month:10 https://dx.doi.org/10.1186/s40200-014-0093-2 kostenfrei Volltext GBV_USEFLAG_A SYSFLAG_A GBV_SPRINGER SSG-OLC-PHA GBV_ILN_11 GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_2003 GBV_ILN_2014 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 13 2014 1 22 10
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Methods The present retrospective cohort was conducted on men and women from 40 to 90 years of age enrolled in the IROSTEOPs study. A phone survey was conducted during 2013 and beginning of 2014 to assess the fractures (traumatic/osteoporotic) occurring at the time of inclusion until the date of the telephone survey, its type and mechanism, and the patient’s age at the time of accident. Survival analysis using Kaplan-Meier product-limit method was performed with the time of fracture as the study outcome. Results Final study population consisted of 1233 individuals, translated in to 9133 person years. The incidence rate of osteoporotic fracture was reported to be 359.1 cases in every 10,000 person years. The 10-year Kaplan-Meier estimate of any kind of major osteoporotic fractures for all the subcohort population was 10.75%. Osteoporosis (HR = 0.75), Discordance between femoral neck and spine (HR = 1.45), Diabetes (HR = 1.81), IBD (HR = 1.84), immobility more than 90 days (HR = 2.19), and personal history of fracture (HR = 7.75) had a considerable effect on the 10-year risk of major osteoporotic fractures. 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author	Ghafoori, Shahnaz
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topic_title	The risk of osteoporotic fractures and its associating risk factors according to the FRAX model in the Iranian patients: a follow-up cohort Fracture (dpeaa)DE-He213 FRAX (dpeaa)DE-He213 Major osteoporotic fracture (dpeaa)DE-He213
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topic_unstemmed	misc Fracture misc FRAX misc Major osteoporotic fracture
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title	The risk of osteoporotic fractures and its associating risk factors according to the FRAX model in the Iranian patients: a follow-up cohort
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title_full	The risk of osteoporotic fractures and its associating risk factors according to the FRAX model in the Iranian patients: a follow-up cohort
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author_browse	Ghafoori, Shahnaz Keshtkar, Abbasali Khashayar, Patricia Ebrahimi, Mehdi Ramezani, Majid Mohammadi, Zahra Saeidifard, Farzane Nemati, Nasrin Khoshbin, Maryam Azizian, Solmaz Zare, Fatemeh Shirazi, Sara Larijani, Bagher
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title_sort	risk of osteoporotic fractures and its associating risk factors according to the frax model in the iranian patients: a follow-up cohort
title_auth	The risk of osteoporotic fractures and its associating risk factors according to the FRAX model in the Iranian patients: a follow-up cohort
abstract	Background The present study is designed to assess the incidence rate of osteoporotic fracture and its risk factors, particularly those used to predict the 10-year risk of osteoporotic fracture in FRAX based on the data gathered through a follow up cohort initiated in 2000. Methods The present retrospective cohort was conducted on men and women from 40 to 90 years of age enrolled in the IROSTEOPs study. A phone survey was conducted during 2013 and beginning of 2014 to assess the fractures (traumatic/osteoporotic) occurring at the time of inclusion until the date of the telephone survey, its type and mechanism, and the patient’s age at the time of accident. Survival analysis using Kaplan-Meier product-limit method was performed with the time of fracture as the study outcome. Results Final study population consisted of 1233 individuals, translated in to 9133 person years. The incidence rate of osteoporotic fracture was reported to be 359.1 cases in every 10,000 person years. The 10-year Kaplan-Meier estimate of any kind of major osteoporotic fractures for all the subcohort population was 10.75%. Osteoporosis (HR = 0.75), Discordance between femoral neck and spine (HR = 1.45), Diabetes (HR = 1.81), IBD (HR = 1.84), immobility more than 90 days (HR = 2.19), and personal history of fracture (HR = 7.75) had a considerable effect on the 10-year risk of major osteoporotic fractures. Conclusions Adding new clinical risk factors to FRAX® may help improve fracture prediction in the Iranian population. © Ghafoori et al.; licensee BioMed Central Ltd. 2014
abstractGer	Background The present study is designed to assess the incidence rate of osteoporotic fracture and its risk factors, particularly those used to predict the 10-year risk of osteoporotic fracture in FRAX based on the data gathered through a follow up cohort initiated in 2000. Methods The present retrospective cohort was conducted on men and women from 40 to 90 years of age enrolled in the IROSTEOPs study. A phone survey was conducted during 2013 and beginning of 2014 to assess the fractures (traumatic/osteoporotic) occurring at the time of inclusion until the date of the telephone survey, its type and mechanism, and the patient’s age at the time of accident. Survival analysis using Kaplan-Meier product-limit method was performed with the time of fracture as the study outcome. Results Final study population consisted of 1233 individuals, translated in to 9133 person years. The incidence rate of osteoporotic fracture was reported to be 359.1 cases in every 10,000 person years. The 10-year Kaplan-Meier estimate of any kind of major osteoporotic fractures for all the subcohort population was 10.75%. Osteoporosis (HR = 0.75), Discordance between femoral neck and spine (HR = 1.45), Diabetes (HR = 1.81), IBD (HR = 1.84), immobility more than 90 days (HR = 2.19), and personal history of fracture (HR = 7.75) had a considerable effect on the 10-year risk of major osteoporotic fractures. Conclusions Adding new clinical risk factors to FRAX® may help improve fracture prediction in the Iranian population. © Ghafoori et al.; licensee BioMed Central Ltd. 2014
abstract_unstemmed	Background The present study is designed to assess the incidence rate of osteoporotic fracture and its risk factors, particularly those used to predict the 10-year risk of osteoporotic fracture in FRAX based on the data gathered through a follow up cohort initiated in 2000. Methods The present retrospective cohort was conducted on men and women from 40 to 90 years of age enrolled in the IROSTEOPs study. A phone survey was conducted during 2013 and beginning of 2014 to assess the fractures (traumatic/osteoporotic) occurring at the time of inclusion until the date of the telephone survey, its type and mechanism, and the patient’s age at the time of accident. Survival analysis using Kaplan-Meier product-limit method was performed with the time of fracture as the study outcome. Results Final study population consisted of 1233 individuals, translated in to 9133 person years. The incidence rate of osteoporotic fracture was reported to be 359.1 cases in every 10,000 person years. The 10-year Kaplan-Meier estimate of any kind of major osteoporotic fractures for all the subcohort population was 10.75%. Osteoporosis (HR = 0.75), Discordance between femoral neck and spine (HR = 1.45), Diabetes (HR = 1.81), IBD (HR = 1.84), immobility more than 90 days (HR = 2.19), and personal history of fracture (HR = 7.75) had a considerable effect on the 10-year risk of major osteoporotic fractures. Conclusions Adding new clinical risk factors to FRAX® may help improve fracture prediction in the Iranian population. © Ghafoori et al.; licensee BioMed Central Ltd. 2014
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title_short	The risk of osteoporotic fractures and its associating risk factors according to the FRAX model in the Iranian patients: a follow-up cohort
url	https://dx.doi.org/10.1186/s40200-014-0093-2
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author2	Keshtkar, Abbasali Khashayar, Patricia Ebrahimi, Mehdi Ramezani, Majid Mohammadi, Zahra Saeidifard, Farzane Nemati, Nasrin Khoshbin, Maryam Azizian, Solmaz Zare, Fatemeh Shirazi, Sara Larijani, Bagher
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up_date	2024-07-03T19:53:01.606Z
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Methods The present retrospective cohort was conducted on men and women from 40 to 90 years of age enrolled in the IROSTEOPs study. A phone survey was conducted during 2013 and beginning of 2014 to assess the fractures (traumatic/osteoporotic) occurring at the time of inclusion until the date of the telephone survey, its type and mechanism, and the patient’s age at the time of accident. Survival analysis using Kaplan-Meier product-limit method was performed with the time of fracture as the study outcome. Results Final study population consisted of 1233 individuals, translated in to 9133 person years. The incidence rate of osteoporotic fracture was reported to be 359.1 cases in every 10,000 person years. The 10-year Kaplan-Meier estimate of any kind of major osteoporotic fractures for all the subcohort population was 10.75%. Osteoporosis (HR = 0.75), Discordance between femoral neck and spine (HR = 1.45), Diabetes (HR = 1.81), IBD (HR = 1.84), immobility more than 90 days (HR = 2.19), and personal history of fracture (HR = 7.75) had a considerable effect on the 10-year risk of major osteoporotic fractures. 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The risk of osteoporotic fractures and its associating risk factors according to the FRAX model in the Iranian patients: a follow-up cohort

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