The Potential Adverse Health Effects of Dental Amalgam
Abstract There is significant public concern about the potential health effects of exposure to mercury vapour ($ Hg^{0} $) released from dental amalgam restorations. The purpose of this article is to provide information about the toxicokinetics of $ Hg^{0} $, evaluate the findings from the recent sc...
Ausführliche Beschreibung
Gespeichert in:
| Autor*in: |
Brownawell, Amy M. [verfasserIn] |
|---|
| Format: |
E-Artikel |
|---|---|
| Sprache: |
Englisch |
| Erschienen: |
2005 |
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| Schlagwörter: |
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| Anmerkung: |
© Adis Data Information BV 2005 |
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| Übergeordnetes Werk: |
Enthalten in: Adverse Drug Reactions and Toxicological Reviews - Springer International Publishing, 2002, 24(2005), 1 vom: März, Seite 1-10 |
|---|---|
| Übergeordnetes Werk: |
volume:24 ; year:2005 ; number:1 ; month:03 ; pages:1-10 |
| Links: |
|---|
| DOI / URN: |
10.2165/00139709-200524010-00001 |
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SPR035350318 |
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| 520 | |a Abstract There is significant public concern about the potential health effects of exposure to mercury vapour ($ Hg^{0} $) released from dental amalgam restorations. The purpose of this article is to provide information about the toxicokinetics of $ Hg^{0} $, evaluate the findings from the recent scientific and medical literature, and identify research gaps that when filled may definitively support or refute the hypothesis that dental amalgam causes adverse health effects. Dental amalgam is a widely used restorative dental material that was introduced over 150 years ago. Most standard dental amalgam formulations contain approximately 50% elemental mercury. Experimental evidence consistently demonstrates that $ Hg^{0} $ is released from dental amalgam restorations and is absorbed by the human body. Numerous studies report positive correlations between the number of dental amalgam restorations or surfaces and urine mercury concentrations in non-occupationally exposed individuals. Although of public concern, it is currently unclear what adverse health effects are caused by the levels of $ Hg^{0} $ released from this restoration material. Historically, studies of occupationally exposed individuals have provided consistent information about the relationship between exposure to $ Hg^{0} $ and adverse effects reflecting both nervous system and renal dysfunction. Workers are usually exposed to substantially higher $ Hg^{0} $ levels than individuals with dental amalgam restorations and are typically exposed 8 hours per day for 20–30 years, whereas persons with dental amalgam restorations are exposed 24 hours per day over some portion of a lifetime. This review has uncovered no convincing evidence pointing to any adverse health effects that are attributable to dental amalgam restorations besides hypersensitivity in some individuals. | ||
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10.2165/00139709-200524010-00001 doi (DE-627)SPR035350318 (SPR)00139709-200524010-00001-e DE-627 ger DE-627 rakwb eng Brownawell, Amy M. verfasserin aut The Potential Adverse Health Effects of Dental Amalgam 2005 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier © Adis Data Information BV 2005 Abstract There is significant public concern about the potential health effects of exposure to mercury vapour ($ Hg^{0} $) released from dental amalgam restorations. The purpose of this article is to provide information about the toxicokinetics of $ Hg^{0} $, evaluate the findings from the recent scientific and medical literature, and identify research gaps that when filled may definitively support or refute the hypothesis that dental amalgam causes adverse health effects. Dental amalgam is a widely used restorative dental material that was introduced over 150 years ago. Most standard dental amalgam formulations contain approximately 50% elemental mercury. Experimental evidence consistently demonstrates that $ Hg^{0} $ is released from dental amalgam restorations and is absorbed by the human body. Numerous studies report positive correlations between the number of dental amalgam restorations or surfaces and urine mercury concentrations in non-occupationally exposed individuals. Although of public concern, it is currently unclear what adverse health effects are caused by the levels of $ Hg^{0} $ released from this restoration material. Historically, studies of occupationally exposed individuals have provided consistent information about the relationship between exposure to $ Hg^{0} $ and adverse effects reflecting both nervous system and renal dysfunction. Workers are usually exposed to substantially higher $ Hg^{0} $ levels than individuals with dental amalgam restorations and are typically exposed 8 hours per day for 20–30 years, whereas persons with dental amalgam restorations are exposed 24 hours per day over some portion of a lifetime. This review has uncovered no convincing evidence pointing to any adverse health effects that are attributable to dental amalgam restorations besides hypersensitivity in some individuals. Mercury (dpeaa)DE-He213 Occupational Exposure (dpeaa)DE-He213 Adverse Health Effect (dpeaa)DE-He213 Inorganic Mercury (dpeaa)DE-He213 Mercury Exposure (dpeaa)DE-He213 Berent, Stanley aut Brent, Robert L. aut Bruckner, James V. aut Doull, John aut Gershwin, Eric M. aut Hood, Ronald D. aut Matanoski, Genevieve M. aut Rubin, Raphael aut Weiss, Bernard aut Karol, Meryl H. aut Enthalten in Adverse Drug Reactions and Toxicological Reviews Springer International Publishing, 2002 24(2005), 1 vom: März, Seite 1-10 (DE-627)SPR035349514 nnns volume:24 year:2005 number:1 month:03 pages:1-10 https://dx.doi.org/10.2165/00139709-200524010-00001 lizenzpflichtig Volltext GBV_USEFLAG_A SYSFLAG_A GBV_SPRINGER SSG-OLC-PHA AR 24 2005 1 03 1-10 |
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10.2165/00139709-200524010-00001 doi (DE-627)SPR035350318 (SPR)00139709-200524010-00001-e DE-627 ger DE-627 rakwb eng Brownawell, Amy M. verfasserin aut The Potential Adverse Health Effects of Dental Amalgam 2005 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier © Adis Data Information BV 2005 Abstract There is significant public concern about the potential health effects of exposure to mercury vapour ($ Hg^{0} $) released from dental amalgam restorations. The purpose of this article is to provide information about the toxicokinetics of $ Hg^{0} $, evaluate the findings from the recent scientific and medical literature, and identify research gaps that when filled may definitively support or refute the hypothesis that dental amalgam causes adverse health effects. Dental amalgam is a widely used restorative dental material that was introduced over 150 years ago. Most standard dental amalgam formulations contain approximately 50% elemental mercury. Experimental evidence consistently demonstrates that $ Hg^{0} $ is released from dental amalgam restorations and is absorbed by the human body. Numerous studies report positive correlations between the number of dental amalgam restorations or surfaces and urine mercury concentrations in non-occupationally exposed individuals. Although of public concern, it is currently unclear what adverse health effects are caused by the levels of $ Hg^{0} $ released from this restoration material. Historically, studies of occupationally exposed individuals have provided consistent information about the relationship between exposure to $ Hg^{0} $ and adverse effects reflecting both nervous system and renal dysfunction. Workers are usually exposed to substantially higher $ Hg^{0} $ levels than individuals with dental amalgam restorations and are typically exposed 8 hours per day for 20–30 years, whereas persons with dental amalgam restorations are exposed 24 hours per day over some portion of a lifetime. This review has uncovered no convincing evidence pointing to any adverse health effects that are attributable to dental amalgam restorations besides hypersensitivity in some individuals. Mercury (dpeaa)DE-He213 Occupational Exposure (dpeaa)DE-He213 Adverse Health Effect (dpeaa)DE-He213 Inorganic Mercury (dpeaa)DE-He213 Mercury Exposure (dpeaa)DE-He213 Berent, Stanley aut Brent, Robert L. aut Bruckner, James V. aut Doull, John aut Gershwin, Eric M. aut Hood, Ronald D. aut Matanoski, Genevieve M. aut Rubin, Raphael aut Weiss, Bernard aut Karol, Meryl H. aut Enthalten in Adverse Drug Reactions and Toxicological Reviews Springer International Publishing, 2002 24(2005), 1 vom: März, Seite 1-10 (DE-627)SPR035349514 nnns volume:24 year:2005 number:1 month:03 pages:1-10 https://dx.doi.org/10.2165/00139709-200524010-00001 lizenzpflichtig Volltext GBV_USEFLAG_A SYSFLAG_A GBV_SPRINGER SSG-OLC-PHA AR 24 2005 1 03 1-10 |
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10.2165/00139709-200524010-00001 doi (DE-627)SPR035350318 (SPR)00139709-200524010-00001-e DE-627 ger DE-627 rakwb eng Brownawell, Amy M. verfasserin aut The Potential Adverse Health Effects of Dental Amalgam 2005 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier © Adis Data Information BV 2005 Abstract There is significant public concern about the potential health effects of exposure to mercury vapour ($ Hg^{0} $) released from dental amalgam restorations. The purpose of this article is to provide information about the toxicokinetics of $ Hg^{0} $, evaluate the findings from the recent scientific and medical literature, and identify research gaps that when filled may definitively support or refute the hypothesis that dental amalgam causes adverse health effects. Dental amalgam is a widely used restorative dental material that was introduced over 150 years ago. Most standard dental amalgam formulations contain approximately 50% elemental mercury. Experimental evidence consistently demonstrates that $ Hg^{0} $ is released from dental amalgam restorations and is absorbed by the human body. Numerous studies report positive correlations between the number of dental amalgam restorations or surfaces and urine mercury concentrations in non-occupationally exposed individuals. Although of public concern, it is currently unclear what adverse health effects are caused by the levels of $ Hg^{0} $ released from this restoration material. Historically, studies of occupationally exposed individuals have provided consistent information about the relationship between exposure to $ Hg^{0} $ and adverse effects reflecting both nervous system and renal dysfunction. Workers are usually exposed to substantially higher $ Hg^{0} $ levels than individuals with dental amalgam restorations and are typically exposed 8 hours per day for 20–30 years, whereas persons with dental amalgam restorations are exposed 24 hours per day over some portion of a lifetime. This review has uncovered no convincing evidence pointing to any adverse health effects that are attributable to dental amalgam restorations besides hypersensitivity in some individuals. Mercury (dpeaa)DE-He213 Occupational Exposure (dpeaa)DE-He213 Adverse Health Effect (dpeaa)DE-He213 Inorganic Mercury (dpeaa)DE-He213 Mercury Exposure (dpeaa)DE-He213 Berent, Stanley aut Brent, Robert L. aut Bruckner, James V. aut Doull, John aut Gershwin, Eric M. aut Hood, Ronald D. aut Matanoski, Genevieve M. aut Rubin, Raphael aut Weiss, Bernard aut Karol, Meryl H. aut Enthalten in Adverse Drug Reactions and Toxicological Reviews Springer International Publishing, 2002 24(2005), 1 vom: März, Seite 1-10 (DE-627)SPR035349514 nnns volume:24 year:2005 number:1 month:03 pages:1-10 https://dx.doi.org/10.2165/00139709-200524010-00001 lizenzpflichtig Volltext GBV_USEFLAG_A SYSFLAG_A GBV_SPRINGER SSG-OLC-PHA AR 24 2005 1 03 1-10 |
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10.2165/00139709-200524010-00001 doi (DE-627)SPR035350318 (SPR)00139709-200524010-00001-e DE-627 ger DE-627 rakwb eng Brownawell, Amy M. verfasserin aut The Potential Adverse Health Effects of Dental Amalgam 2005 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier © Adis Data Information BV 2005 Abstract There is significant public concern about the potential health effects of exposure to mercury vapour ($ Hg^{0} $) released from dental amalgam restorations. The purpose of this article is to provide information about the toxicokinetics of $ Hg^{0} $, evaluate the findings from the recent scientific and medical literature, and identify research gaps that when filled may definitively support or refute the hypothesis that dental amalgam causes adverse health effects. Dental amalgam is a widely used restorative dental material that was introduced over 150 years ago. Most standard dental amalgam formulations contain approximately 50% elemental mercury. Experimental evidence consistently demonstrates that $ Hg^{0} $ is released from dental amalgam restorations and is absorbed by the human body. Numerous studies report positive correlations between the number of dental amalgam restorations or surfaces and urine mercury concentrations in non-occupationally exposed individuals. Although of public concern, it is currently unclear what adverse health effects are caused by the levels of $ Hg^{0} $ released from this restoration material. Historically, studies of occupationally exposed individuals have provided consistent information about the relationship between exposure to $ Hg^{0} $ and adverse effects reflecting both nervous system and renal dysfunction. Workers are usually exposed to substantially higher $ Hg^{0} $ levels than individuals with dental amalgam restorations and are typically exposed 8 hours per day for 20–30 years, whereas persons with dental amalgam restorations are exposed 24 hours per day over some portion of a lifetime. This review has uncovered no convincing evidence pointing to any adverse health effects that are attributable to dental amalgam restorations besides hypersensitivity in some individuals. Mercury (dpeaa)DE-He213 Occupational Exposure (dpeaa)DE-He213 Adverse Health Effect (dpeaa)DE-He213 Inorganic Mercury (dpeaa)DE-He213 Mercury Exposure (dpeaa)DE-He213 Berent, Stanley aut Brent, Robert L. aut Bruckner, James V. aut Doull, John aut Gershwin, Eric M. aut Hood, Ronald D. aut Matanoski, Genevieve M. aut Rubin, Raphael aut Weiss, Bernard aut Karol, Meryl H. aut Enthalten in Adverse Drug Reactions and Toxicological Reviews Springer International Publishing, 2002 24(2005), 1 vom: März, Seite 1-10 (DE-627)SPR035349514 nnns volume:24 year:2005 number:1 month:03 pages:1-10 https://dx.doi.org/10.2165/00139709-200524010-00001 lizenzpflichtig Volltext GBV_USEFLAG_A SYSFLAG_A GBV_SPRINGER SSG-OLC-PHA AR 24 2005 1 03 1-10 |
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10.2165/00139709-200524010-00001 doi (DE-627)SPR035350318 (SPR)00139709-200524010-00001-e DE-627 ger DE-627 rakwb eng Brownawell, Amy M. verfasserin aut The Potential Adverse Health Effects of Dental Amalgam 2005 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier © Adis Data Information BV 2005 Abstract There is significant public concern about the potential health effects of exposure to mercury vapour ($ Hg^{0} $) released from dental amalgam restorations. The purpose of this article is to provide information about the toxicokinetics of $ Hg^{0} $, evaluate the findings from the recent scientific and medical literature, and identify research gaps that when filled may definitively support or refute the hypothesis that dental amalgam causes adverse health effects. Dental amalgam is a widely used restorative dental material that was introduced over 150 years ago. Most standard dental amalgam formulations contain approximately 50% elemental mercury. Experimental evidence consistently demonstrates that $ Hg^{0} $ is released from dental amalgam restorations and is absorbed by the human body. Numerous studies report positive correlations between the number of dental amalgam restorations or surfaces and urine mercury concentrations in non-occupationally exposed individuals. Although of public concern, it is currently unclear what adverse health effects are caused by the levels of $ Hg^{0} $ released from this restoration material. Historically, studies of occupationally exposed individuals have provided consistent information about the relationship between exposure to $ Hg^{0} $ and adverse effects reflecting both nervous system and renal dysfunction. Workers are usually exposed to substantially higher $ Hg^{0} $ levels than individuals with dental amalgam restorations and are typically exposed 8 hours per day for 20–30 years, whereas persons with dental amalgam restorations are exposed 24 hours per day over some portion of a lifetime. This review has uncovered no convincing evidence pointing to any adverse health effects that are attributable to dental amalgam restorations besides hypersensitivity in some individuals. Mercury (dpeaa)DE-He213 Occupational Exposure (dpeaa)DE-He213 Adverse Health Effect (dpeaa)DE-He213 Inorganic Mercury (dpeaa)DE-He213 Mercury Exposure (dpeaa)DE-He213 Berent, Stanley aut Brent, Robert L. aut Bruckner, James V. aut Doull, John aut Gershwin, Eric M. aut Hood, Ronald D. aut Matanoski, Genevieve M. aut Rubin, Raphael aut Weiss, Bernard aut Karol, Meryl H. aut Enthalten in Adverse Drug Reactions and Toxicological Reviews Springer International Publishing, 2002 24(2005), 1 vom: März, Seite 1-10 (DE-627)SPR035349514 nnns volume:24 year:2005 number:1 month:03 pages:1-10 https://dx.doi.org/10.2165/00139709-200524010-00001 lizenzpflichtig Volltext GBV_USEFLAG_A SYSFLAG_A GBV_SPRINGER SSG-OLC-PHA AR 24 2005 1 03 1-10 |
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The Potential Adverse Health Effects of Dental Amalgam Mercury (dpeaa)DE-He213 Occupational Exposure (dpeaa)DE-He213 Adverse Health Effect (dpeaa)DE-He213 Inorganic Mercury (dpeaa)DE-He213 Mercury Exposure (dpeaa)DE-He213 |
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The Potential Adverse Health Effects of Dental Amalgam |
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The Potential Adverse Health Effects of Dental Amalgam |
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Brownawell, Amy M. |
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Brownawell, Amy M. Berent, Stanley Brent, Robert L. Bruckner, James V. Doull, John Gershwin, Eric M. Hood, Ronald D. Matanoski, Genevieve M. Rubin, Raphael Weiss, Bernard Karol, Meryl H. |
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potential adverse health effects of dental amalgam |
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The Potential Adverse Health Effects of Dental Amalgam |
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Abstract There is significant public concern about the potential health effects of exposure to mercury vapour ($ Hg^{0} $) released from dental amalgam restorations. The purpose of this article is to provide information about the toxicokinetics of $ Hg^{0} $, evaluate the findings from the recent scientific and medical literature, and identify research gaps that when filled may definitively support or refute the hypothesis that dental amalgam causes adverse health effects. Dental amalgam is a widely used restorative dental material that was introduced over 150 years ago. Most standard dental amalgam formulations contain approximately 50% elemental mercury. Experimental evidence consistently demonstrates that $ Hg^{0} $ is released from dental amalgam restorations and is absorbed by the human body. Numerous studies report positive correlations between the number of dental amalgam restorations or surfaces and urine mercury concentrations in non-occupationally exposed individuals. Although of public concern, it is currently unclear what adverse health effects are caused by the levels of $ Hg^{0} $ released from this restoration material. Historically, studies of occupationally exposed individuals have provided consistent information about the relationship between exposure to $ Hg^{0} $ and adverse effects reflecting both nervous system and renal dysfunction. Workers are usually exposed to substantially higher $ Hg^{0} $ levels than individuals with dental amalgam restorations and are typically exposed 8 hours per day for 20–30 years, whereas persons with dental amalgam restorations are exposed 24 hours per day over some portion of a lifetime. This review has uncovered no convincing evidence pointing to any adverse health effects that are attributable to dental amalgam restorations besides hypersensitivity in some individuals. © Adis Data Information BV 2005 |
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Abstract There is significant public concern about the potential health effects of exposure to mercury vapour ($ Hg^{0} $) released from dental amalgam restorations. The purpose of this article is to provide information about the toxicokinetics of $ Hg^{0} $, evaluate the findings from the recent scientific and medical literature, and identify research gaps that when filled may definitively support or refute the hypothesis that dental amalgam causes adverse health effects. Dental amalgam is a widely used restorative dental material that was introduced over 150 years ago. Most standard dental amalgam formulations contain approximately 50% elemental mercury. Experimental evidence consistently demonstrates that $ Hg^{0} $ is released from dental amalgam restorations and is absorbed by the human body. Numerous studies report positive correlations between the number of dental amalgam restorations or surfaces and urine mercury concentrations in non-occupationally exposed individuals. Although of public concern, it is currently unclear what adverse health effects are caused by the levels of $ Hg^{0} $ released from this restoration material. Historically, studies of occupationally exposed individuals have provided consistent information about the relationship between exposure to $ Hg^{0} $ and adverse effects reflecting both nervous system and renal dysfunction. Workers are usually exposed to substantially higher $ Hg^{0} $ levels than individuals with dental amalgam restorations and are typically exposed 8 hours per day for 20–30 years, whereas persons with dental amalgam restorations are exposed 24 hours per day over some portion of a lifetime. This review has uncovered no convincing evidence pointing to any adverse health effects that are attributable to dental amalgam restorations besides hypersensitivity in some individuals. © Adis Data Information BV 2005 |
| abstract_unstemmed |
Abstract There is significant public concern about the potential health effects of exposure to mercury vapour ($ Hg^{0} $) released from dental amalgam restorations. The purpose of this article is to provide information about the toxicokinetics of $ Hg^{0} $, evaluate the findings from the recent scientific and medical literature, and identify research gaps that when filled may definitively support or refute the hypothesis that dental amalgam causes adverse health effects. Dental amalgam is a widely used restorative dental material that was introduced over 150 years ago. Most standard dental amalgam formulations contain approximately 50% elemental mercury. Experimental evidence consistently demonstrates that $ Hg^{0} $ is released from dental amalgam restorations and is absorbed by the human body. Numerous studies report positive correlations between the number of dental amalgam restorations or surfaces and urine mercury concentrations in non-occupationally exposed individuals. Although of public concern, it is currently unclear what adverse health effects are caused by the levels of $ Hg^{0} $ released from this restoration material. Historically, studies of occupationally exposed individuals have provided consistent information about the relationship between exposure to $ Hg^{0} $ and adverse effects reflecting both nervous system and renal dysfunction. Workers are usually exposed to substantially higher $ Hg^{0} $ levels than individuals with dental amalgam restorations and are typically exposed 8 hours per day for 20–30 years, whereas persons with dental amalgam restorations are exposed 24 hours per day over some portion of a lifetime. This review has uncovered no convincing evidence pointing to any adverse health effects that are attributable to dental amalgam restorations besides hypersensitivity in some individuals. © Adis Data Information BV 2005 |
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