The diminished cardiac performance in severe thyrotoxicosis. Parabolic correlation of LVET/PEP to the circulating levels of thyroid hormones
Abstract Fifteen patients with thyrotoxicosis, 8 patients with primary hypothyroidism and 15 normal subjects were studied to assess the correlation between systolic time intervals and serum levels of thyroid hormones. In hypothyroid patients, prolongation of PEPc (corrected pre-ejection period), sho...
Ausführliche Beschreibung
Gespeichert in:
| Autor*in: |
Suzuki, Hitoshi [verfasserIn] |
|---|
| Format: |
E-Artikel |
|---|---|
| Sprache: |
Englisch |
| Erschienen: |
1981 |
|---|
| Anmerkung: |
© Italian Society of Endocrinology (SIE) 1981 |
|---|
| Übergeordnetes Werk: |
Enthalten in: Journal of endocrinological investigation - [S. l.] : Springer, 1978, 4(1981), 3 vom: Juli, Seite 289-294 |
|---|---|
| Übergeordnetes Werk: |
volume:4 ; year:1981 ; number:3 ; month:07 ; pages:289-294 |
| Links: |
|---|
| DOI / URN: |
10.1007/BF03349446 |
|---|
| Katalog-ID: |
SPR036785822 |
|---|
| LEADER | 01000caa a22002652 4500 | ||
|---|---|---|---|
| 001 | SPR036785822 | ||
| 003 | DE-627 | ||
| 005 | 20230519183321.0 | ||
| 007 | cr uuu---uuuuu | ||
| 008 | 201007s1981 xx |||||o 00| ||eng c | ||
| 024 | 7 | |a 10.1007/BF03349446 |2 doi | |
| 035 | |a (DE-627)SPR036785822 | ||
| 035 | |a (SPR)BF03349446-e | ||
| 040 | |a DE-627 |b ger |c DE-627 |e rakwb | ||
| 041 | |a eng | ||
| 100 | 1 | |a Suzuki, Hitoshi |e verfasserin |4 aut | |
| 245 | 1 | 4 | |a The diminished cardiac performance in severe thyrotoxicosis. Parabolic correlation of LVET/PEP to the circulating levels of thyroid hormones |
| 264 | 1 | |c 1981 | |
| 336 | |a Text |b txt |2 rdacontent | ||
| 337 | |a Computermedien |b c |2 rdamedia | ||
| 338 | |a Online-Ressource |b cr |2 rdacarrier | ||
| 500 | |a © Italian Society of Endocrinology (SIE) 1981 | ||
| 520 | |a Abstract Fifteen patients with thyrotoxicosis, 8 patients with primary hypothyroidism and 15 normal subjects were studied to assess the correlation between systolic time intervals and serum levels of thyroid hormones. In hypothyroid patients, prolongation of PEPc (corrected pre-ejection period), shortening of LVETc (corrected left ventricular ejection time) and low values of LVET/PEP ratio and cardiac output were improved after restoration of thyroid function. In thyrotoxic patients, shortening of PEPc, high values of LVET/PEP ratio and cardiac output were normalized after correction of thyroid function. As contrasted with these observations, in 5 severely thyrotoxic patients, low values of LVET/PEP ratio and cardiac output for thyrotoxicosis were observed; these were not significantly decreased after antithyroid drug treatment, but appeared to have a tendency to increase. Performing polynomial regression analysis, a significant parabolic correlation was found between LVET/PEP and serum $ T_{4} $ or $ T_{3} $(p < 0.0001). From these results, it might be concluded that large amounts of thyroid hormones suppress cardiac performance. | ||
| 700 | 1 | |a Kasai, K. |4 aut | |
| 700 | 1 | |a Shimoda, S. I. |4 aut | |
| 773 | 0 | 8 | |i Enthalten in |t Journal of endocrinological investigation |d [S. l.] : Springer, 1978 |g 4(1981), 3 vom: Juli, Seite 289-294 |w (DE-627)369556267 |w (DE-600)2119482-8 |x 1720-8386 |7 nnns |
| 773 | 1 | 8 | |g volume:4 |g year:1981 |g number:3 |g month:07 |g pages:289-294 |
| 856 | 4 | 0 | |u https://dx.doi.org/10.1007/BF03349446 |z lizenzpflichtig |3 Volltext |
| 912 | |a GBV_USEFLAG_A | ||
| 912 | |a SYSFLAG_A | ||
| 912 | |a GBV_SPRINGER | ||
| 912 | |a SSG-OLC-PHA | ||
| 912 | |a GBV_ILN_702 | ||
| 912 | |a GBV_ILN_2190 | ||
| 951 | |a AR | ||
| 952 | |d 4 |j 1981 |e 3 |c 07 |h 289-294 | ||
| author_variant |
h s hs k k kk s i s si sis |
|---|---|
| matchkey_str |
article:17208386:1981----::hdmnsecricefracisvrtyooioiprblcorltooleppohcr |
| hierarchy_sort_str |
1981 |
| publishDate |
1981 |
| allfields |
10.1007/BF03349446 doi (DE-627)SPR036785822 (SPR)BF03349446-e DE-627 ger DE-627 rakwb eng Suzuki, Hitoshi verfasserin aut The diminished cardiac performance in severe thyrotoxicosis. Parabolic correlation of LVET/PEP to the circulating levels of thyroid hormones 1981 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier © Italian Society of Endocrinology (SIE) 1981 Abstract Fifteen patients with thyrotoxicosis, 8 patients with primary hypothyroidism and 15 normal subjects were studied to assess the correlation between systolic time intervals and serum levels of thyroid hormones. In hypothyroid patients, prolongation of PEPc (corrected pre-ejection period), shortening of LVETc (corrected left ventricular ejection time) and low values of LVET/PEP ratio and cardiac output were improved after restoration of thyroid function. In thyrotoxic patients, shortening of PEPc, high values of LVET/PEP ratio and cardiac output were normalized after correction of thyroid function. As contrasted with these observations, in 5 severely thyrotoxic patients, low values of LVET/PEP ratio and cardiac output for thyrotoxicosis were observed; these were not significantly decreased after antithyroid drug treatment, but appeared to have a tendency to increase. Performing polynomial regression analysis, a significant parabolic correlation was found between LVET/PEP and serum $ T_{4} $ or $ T_{3} $(p < 0.0001). From these results, it might be concluded that large amounts of thyroid hormones suppress cardiac performance. Kasai, K. aut Shimoda, S. I. aut Enthalten in Journal of endocrinological investigation [S. l.] : Springer, 1978 4(1981), 3 vom: Juli, Seite 289-294 (DE-627)369556267 (DE-600)2119482-8 1720-8386 nnns volume:4 year:1981 number:3 month:07 pages:289-294 https://dx.doi.org/10.1007/BF03349446 lizenzpflichtig Volltext GBV_USEFLAG_A SYSFLAG_A GBV_SPRINGER SSG-OLC-PHA GBV_ILN_702 GBV_ILN_2190 AR 4 1981 3 07 289-294 |
| spelling |
10.1007/BF03349446 doi (DE-627)SPR036785822 (SPR)BF03349446-e DE-627 ger DE-627 rakwb eng Suzuki, Hitoshi verfasserin aut The diminished cardiac performance in severe thyrotoxicosis. Parabolic correlation of LVET/PEP to the circulating levels of thyroid hormones 1981 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier © Italian Society of Endocrinology (SIE) 1981 Abstract Fifteen patients with thyrotoxicosis, 8 patients with primary hypothyroidism and 15 normal subjects were studied to assess the correlation between systolic time intervals and serum levels of thyroid hormones. In hypothyroid patients, prolongation of PEPc (corrected pre-ejection period), shortening of LVETc (corrected left ventricular ejection time) and low values of LVET/PEP ratio and cardiac output were improved after restoration of thyroid function. In thyrotoxic patients, shortening of PEPc, high values of LVET/PEP ratio and cardiac output were normalized after correction of thyroid function. As contrasted with these observations, in 5 severely thyrotoxic patients, low values of LVET/PEP ratio and cardiac output for thyrotoxicosis were observed; these were not significantly decreased after antithyroid drug treatment, but appeared to have a tendency to increase. Performing polynomial regression analysis, a significant parabolic correlation was found between LVET/PEP and serum $ T_{4} $ or $ T_{3} $(p < 0.0001). From these results, it might be concluded that large amounts of thyroid hormones suppress cardiac performance. Kasai, K. aut Shimoda, S. I. aut Enthalten in Journal of endocrinological investigation [S. l.] : Springer, 1978 4(1981), 3 vom: Juli, Seite 289-294 (DE-627)369556267 (DE-600)2119482-8 1720-8386 nnns volume:4 year:1981 number:3 month:07 pages:289-294 https://dx.doi.org/10.1007/BF03349446 lizenzpflichtig Volltext GBV_USEFLAG_A SYSFLAG_A GBV_SPRINGER SSG-OLC-PHA GBV_ILN_702 GBV_ILN_2190 AR 4 1981 3 07 289-294 |
| allfields_unstemmed |
10.1007/BF03349446 doi (DE-627)SPR036785822 (SPR)BF03349446-e DE-627 ger DE-627 rakwb eng Suzuki, Hitoshi verfasserin aut The diminished cardiac performance in severe thyrotoxicosis. Parabolic correlation of LVET/PEP to the circulating levels of thyroid hormones 1981 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier © Italian Society of Endocrinology (SIE) 1981 Abstract Fifteen patients with thyrotoxicosis, 8 patients with primary hypothyroidism and 15 normal subjects were studied to assess the correlation between systolic time intervals and serum levels of thyroid hormones. In hypothyroid patients, prolongation of PEPc (corrected pre-ejection period), shortening of LVETc (corrected left ventricular ejection time) and low values of LVET/PEP ratio and cardiac output were improved after restoration of thyroid function. In thyrotoxic patients, shortening of PEPc, high values of LVET/PEP ratio and cardiac output were normalized after correction of thyroid function. As contrasted with these observations, in 5 severely thyrotoxic patients, low values of LVET/PEP ratio and cardiac output for thyrotoxicosis were observed; these were not significantly decreased after antithyroid drug treatment, but appeared to have a tendency to increase. Performing polynomial regression analysis, a significant parabolic correlation was found between LVET/PEP and serum $ T_{4} $ or $ T_{3} $(p < 0.0001). From these results, it might be concluded that large amounts of thyroid hormones suppress cardiac performance. Kasai, K. aut Shimoda, S. I. aut Enthalten in Journal of endocrinological investigation [S. l.] : Springer, 1978 4(1981), 3 vom: Juli, Seite 289-294 (DE-627)369556267 (DE-600)2119482-8 1720-8386 nnns volume:4 year:1981 number:3 month:07 pages:289-294 https://dx.doi.org/10.1007/BF03349446 lizenzpflichtig Volltext GBV_USEFLAG_A SYSFLAG_A GBV_SPRINGER SSG-OLC-PHA GBV_ILN_702 GBV_ILN_2190 AR 4 1981 3 07 289-294 |
| allfieldsGer |
10.1007/BF03349446 doi (DE-627)SPR036785822 (SPR)BF03349446-e DE-627 ger DE-627 rakwb eng Suzuki, Hitoshi verfasserin aut The diminished cardiac performance in severe thyrotoxicosis. Parabolic correlation of LVET/PEP to the circulating levels of thyroid hormones 1981 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier © Italian Society of Endocrinology (SIE) 1981 Abstract Fifteen patients with thyrotoxicosis, 8 patients with primary hypothyroidism and 15 normal subjects were studied to assess the correlation between systolic time intervals and serum levels of thyroid hormones. In hypothyroid patients, prolongation of PEPc (corrected pre-ejection period), shortening of LVETc (corrected left ventricular ejection time) and low values of LVET/PEP ratio and cardiac output were improved after restoration of thyroid function. In thyrotoxic patients, shortening of PEPc, high values of LVET/PEP ratio and cardiac output were normalized after correction of thyroid function. As contrasted with these observations, in 5 severely thyrotoxic patients, low values of LVET/PEP ratio and cardiac output for thyrotoxicosis were observed; these were not significantly decreased after antithyroid drug treatment, but appeared to have a tendency to increase. Performing polynomial regression analysis, a significant parabolic correlation was found between LVET/PEP and serum $ T_{4} $ or $ T_{3} $(p < 0.0001). From these results, it might be concluded that large amounts of thyroid hormones suppress cardiac performance. Kasai, K. aut Shimoda, S. I. aut Enthalten in Journal of endocrinological investigation [S. l.] : Springer, 1978 4(1981), 3 vom: Juli, Seite 289-294 (DE-627)369556267 (DE-600)2119482-8 1720-8386 nnns volume:4 year:1981 number:3 month:07 pages:289-294 https://dx.doi.org/10.1007/BF03349446 lizenzpflichtig Volltext GBV_USEFLAG_A SYSFLAG_A GBV_SPRINGER SSG-OLC-PHA GBV_ILN_702 GBV_ILN_2190 AR 4 1981 3 07 289-294 |
| allfieldsSound |
10.1007/BF03349446 doi (DE-627)SPR036785822 (SPR)BF03349446-e DE-627 ger DE-627 rakwb eng Suzuki, Hitoshi verfasserin aut The diminished cardiac performance in severe thyrotoxicosis. Parabolic correlation of LVET/PEP to the circulating levels of thyroid hormones 1981 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier © Italian Society of Endocrinology (SIE) 1981 Abstract Fifteen patients with thyrotoxicosis, 8 patients with primary hypothyroidism and 15 normal subjects were studied to assess the correlation between systolic time intervals and serum levels of thyroid hormones. In hypothyroid patients, prolongation of PEPc (corrected pre-ejection period), shortening of LVETc (corrected left ventricular ejection time) and low values of LVET/PEP ratio and cardiac output were improved after restoration of thyroid function. In thyrotoxic patients, shortening of PEPc, high values of LVET/PEP ratio and cardiac output were normalized after correction of thyroid function. As contrasted with these observations, in 5 severely thyrotoxic patients, low values of LVET/PEP ratio and cardiac output for thyrotoxicosis were observed; these were not significantly decreased after antithyroid drug treatment, but appeared to have a tendency to increase. Performing polynomial regression analysis, a significant parabolic correlation was found between LVET/PEP and serum $ T_{4} $ or $ T_{3} $(p < 0.0001). From these results, it might be concluded that large amounts of thyroid hormones suppress cardiac performance. Kasai, K. aut Shimoda, S. I. aut Enthalten in Journal of endocrinological investigation [S. l.] : Springer, 1978 4(1981), 3 vom: Juli, Seite 289-294 (DE-627)369556267 (DE-600)2119482-8 1720-8386 nnns volume:4 year:1981 number:3 month:07 pages:289-294 https://dx.doi.org/10.1007/BF03349446 lizenzpflichtig Volltext GBV_USEFLAG_A SYSFLAG_A GBV_SPRINGER SSG-OLC-PHA GBV_ILN_702 GBV_ILN_2190 AR 4 1981 3 07 289-294 |
| language |
English |
| source |
Enthalten in Journal of endocrinological investigation 4(1981), 3 vom: Juli, Seite 289-294 volume:4 year:1981 number:3 month:07 pages:289-294 |
| sourceStr |
Enthalten in Journal of endocrinological investigation 4(1981), 3 vom: Juli, Seite 289-294 volume:4 year:1981 number:3 month:07 pages:289-294 |
| format_phy_str_mv |
Article |
| institution |
findex.gbv.de |
| isfreeaccess_bool |
false |
| container_title |
Journal of endocrinological investigation |
| authorswithroles_txt_mv |
Suzuki, Hitoshi @@aut@@ Kasai, K. @@aut@@ Shimoda, S. I. @@aut@@ |
| publishDateDaySort_date |
1981-07-01T00:00:00Z |
| hierarchy_top_id |
369556267 |
| id |
SPR036785822 |
| language_de |
englisch |
| fullrecord |
<?xml version="1.0" encoding="UTF-8"?><collection xmlns="http://www.loc.gov/MARC21/slim"><record><leader>01000caa a22002652 4500</leader><controlfield tag="001">SPR036785822</controlfield><controlfield tag="003">DE-627</controlfield><controlfield tag="005">20230519183321.0</controlfield><controlfield tag="007">cr uuu---uuuuu</controlfield><controlfield tag="008">201007s1981 xx |||||o 00| ||eng c</controlfield><datafield tag="024" ind1="7" ind2=" "><subfield code="a">10.1007/BF03349446</subfield><subfield code="2">doi</subfield></datafield><datafield tag="035" ind1=" " ind2=" "><subfield code="a">(DE-627)SPR036785822</subfield></datafield><datafield tag="035" ind1=" " ind2=" "><subfield code="a">(SPR)BF03349446-e</subfield></datafield><datafield tag="040" ind1=" " ind2=" "><subfield code="a">DE-627</subfield><subfield code="b">ger</subfield><subfield code="c">DE-627</subfield><subfield code="e">rakwb</subfield></datafield><datafield tag="041" ind1=" " ind2=" "><subfield code="a">eng</subfield></datafield><datafield tag="100" ind1="1" ind2=" "><subfield code="a">Suzuki, Hitoshi</subfield><subfield code="e">verfasserin</subfield><subfield code="4">aut</subfield></datafield><datafield tag="245" ind1="1" ind2="4"><subfield code="a">The diminished cardiac performance in severe thyrotoxicosis. Parabolic correlation of LVET/PEP to the circulating levels of thyroid hormones</subfield></datafield><datafield tag="264" ind1=" " ind2="1"><subfield code="c">1981</subfield></datafield><datafield tag="336" ind1=" " ind2=" "><subfield code="a">Text</subfield><subfield code="b">txt</subfield><subfield code="2">rdacontent</subfield></datafield><datafield tag="337" ind1=" " ind2=" "><subfield code="a">Computermedien</subfield><subfield code="b">c</subfield><subfield code="2">rdamedia</subfield></datafield><datafield tag="338" ind1=" " ind2=" "><subfield code="a">Online-Ressource</subfield><subfield code="b">cr</subfield><subfield code="2">rdacarrier</subfield></datafield><datafield tag="500" ind1=" " ind2=" "><subfield code="a">© Italian Society of Endocrinology (SIE) 1981</subfield></datafield><datafield tag="520" ind1=" " ind2=" "><subfield code="a">Abstract Fifteen patients with thyrotoxicosis, 8 patients with primary hypothyroidism and 15 normal subjects were studied to assess the correlation between systolic time intervals and serum levels of thyroid hormones. In hypothyroid patients, prolongation of PEPc (corrected pre-ejection period), shortening of LVETc (corrected left ventricular ejection time) and low values of LVET/PEP ratio and cardiac output were improved after restoration of thyroid function. In thyrotoxic patients, shortening of PEPc, high values of LVET/PEP ratio and cardiac output were normalized after correction of thyroid function. As contrasted with these observations, in 5 severely thyrotoxic patients, low values of LVET/PEP ratio and cardiac output for thyrotoxicosis were observed; these were not significantly decreased after antithyroid drug treatment, but appeared to have a tendency to increase. Performing polynomial regression analysis, a significant parabolic correlation was found between LVET/PEP and serum $ T_{4} $ or $ T_{3} $(p < 0.0001). From these results, it might be concluded that large amounts of thyroid hormones suppress cardiac performance.</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Kasai, K.</subfield><subfield code="4">aut</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Shimoda, S. I.</subfield><subfield code="4">aut</subfield></datafield><datafield tag="773" ind1="0" ind2="8"><subfield code="i">Enthalten in</subfield><subfield code="t">Journal of endocrinological investigation</subfield><subfield code="d">[S. l.] : Springer, 1978</subfield><subfield code="g">4(1981), 3 vom: Juli, Seite 289-294</subfield><subfield code="w">(DE-627)369556267</subfield><subfield code="w">(DE-600)2119482-8</subfield><subfield code="x">1720-8386</subfield><subfield code="7">nnns</subfield></datafield><datafield tag="773" ind1="1" ind2="8"><subfield code="g">volume:4</subfield><subfield code="g">year:1981</subfield><subfield code="g">number:3</subfield><subfield code="g">month:07</subfield><subfield code="g">pages:289-294</subfield></datafield><datafield tag="856" ind1="4" ind2="0"><subfield code="u">https://dx.doi.org/10.1007/BF03349446</subfield><subfield code="z">lizenzpflichtig</subfield><subfield code="3">Volltext</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_USEFLAG_A</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">SYSFLAG_A</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_SPRINGER</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">SSG-OLC-PHA</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_702</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_2190</subfield></datafield><datafield tag="951" ind1=" " ind2=" "><subfield code="a">AR</subfield></datafield><datafield tag="952" ind1=" " ind2=" "><subfield code="d">4</subfield><subfield code="j">1981</subfield><subfield code="e">3</subfield><subfield code="c">07</subfield><subfield code="h">289-294</subfield></datafield></record></collection>
|
| author |
Suzuki, Hitoshi |
| spellingShingle |
Suzuki, Hitoshi The diminished cardiac performance in severe thyrotoxicosis. Parabolic correlation of LVET/PEP to the circulating levels of thyroid hormones |
| authorStr |
Suzuki, Hitoshi |
| ppnlink_with_tag_str_mv |
@@773@@(DE-627)369556267 |
| format |
electronic Article |
| delete_txt_mv |
keep |
| author_role |
aut aut aut |
| collection |
springer |
| remote_str |
true |
| illustrated |
Not Illustrated |
| issn |
1720-8386 |
| topic_title |
The diminished cardiac performance in severe thyrotoxicosis. Parabolic correlation of LVET/PEP to the circulating levels of thyroid hormones |
| format_facet |
Elektronische Aufsätze Aufsätze Elektronische Ressource |
| format_main_str_mv |
Text Zeitschrift/Artikel |
| carriertype_str_mv |
cr |
| hierarchy_parent_title |
Journal of endocrinological investigation |
| hierarchy_parent_id |
369556267 |
| hierarchy_top_title |
Journal of endocrinological investigation |
| isfreeaccess_txt |
false |
| familylinks_str_mv |
(DE-627)369556267 (DE-600)2119482-8 |
| title |
The diminished cardiac performance in severe thyrotoxicosis. Parabolic correlation of LVET/PEP to the circulating levels of thyroid hormones |
| ctrlnum |
(DE-627)SPR036785822 (SPR)BF03349446-e |
| title_full |
The diminished cardiac performance in severe thyrotoxicosis. Parabolic correlation of LVET/PEP to the circulating levels of thyroid hormones |
| author_sort |
Suzuki, Hitoshi |
| journal |
Journal of endocrinological investigation |
| journalStr |
Journal of endocrinological investigation |
| lang_code |
eng |
| isOA_bool |
false |
| recordtype |
marc |
| publishDateSort |
1981 |
| contenttype_str_mv |
txt |
| container_start_page |
289 |
| author_browse |
Suzuki, Hitoshi Kasai, K. Shimoda, S. I. |
| container_volume |
4 |
| format_se |
Elektronische Aufsätze |
| author-letter |
Suzuki, Hitoshi |
| doi_str_mv |
10.1007/BF03349446 |
| title_sort |
diminished cardiac performance in severe thyrotoxicosis. parabolic correlation of lvet/pep to the circulating levels of thyroid hormones |
| title_auth |
The diminished cardiac performance in severe thyrotoxicosis. Parabolic correlation of LVET/PEP to the circulating levels of thyroid hormones |
| abstract |
Abstract Fifteen patients with thyrotoxicosis, 8 patients with primary hypothyroidism and 15 normal subjects were studied to assess the correlation between systolic time intervals and serum levels of thyroid hormones. In hypothyroid patients, prolongation of PEPc (corrected pre-ejection period), shortening of LVETc (corrected left ventricular ejection time) and low values of LVET/PEP ratio and cardiac output were improved after restoration of thyroid function. In thyrotoxic patients, shortening of PEPc, high values of LVET/PEP ratio and cardiac output were normalized after correction of thyroid function. As contrasted with these observations, in 5 severely thyrotoxic patients, low values of LVET/PEP ratio and cardiac output for thyrotoxicosis were observed; these were not significantly decreased after antithyroid drug treatment, but appeared to have a tendency to increase. Performing polynomial regression analysis, a significant parabolic correlation was found between LVET/PEP and serum $ T_{4} $ or $ T_{3} $(p < 0.0001). From these results, it might be concluded that large amounts of thyroid hormones suppress cardiac performance. © Italian Society of Endocrinology (SIE) 1981 |
| abstractGer |
Abstract Fifteen patients with thyrotoxicosis, 8 patients with primary hypothyroidism and 15 normal subjects were studied to assess the correlation between systolic time intervals and serum levels of thyroid hormones. In hypothyroid patients, prolongation of PEPc (corrected pre-ejection period), shortening of LVETc (corrected left ventricular ejection time) and low values of LVET/PEP ratio and cardiac output were improved after restoration of thyroid function. In thyrotoxic patients, shortening of PEPc, high values of LVET/PEP ratio and cardiac output were normalized after correction of thyroid function. As contrasted with these observations, in 5 severely thyrotoxic patients, low values of LVET/PEP ratio and cardiac output for thyrotoxicosis were observed; these were not significantly decreased after antithyroid drug treatment, but appeared to have a tendency to increase. Performing polynomial regression analysis, a significant parabolic correlation was found between LVET/PEP and serum $ T_{4} $ or $ T_{3} $(p < 0.0001). From these results, it might be concluded that large amounts of thyroid hormones suppress cardiac performance. © Italian Society of Endocrinology (SIE) 1981 |
| abstract_unstemmed |
Abstract Fifteen patients with thyrotoxicosis, 8 patients with primary hypothyroidism and 15 normal subjects were studied to assess the correlation between systolic time intervals and serum levels of thyroid hormones. In hypothyroid patients, prolongation of PEPc (corrected pre-ejection period), shortening of LVETc (corrected left ventricular ejection time) and low values of LVET/PEP ratio and cardiac output were improved after restoration of thyroid function. In thyrotoxic patients, shortening of PEPc, high values of LVET/PEP ratio and cardiac output were normalized after correction of thyroid function. As contrasted with these observations, in 5 severely thyrotoxic patients, low values of LVET/PEP ratio and cardiac output for thyrotoxicosis were observed; these were not significantly decreased after antithyroid drug treatment, but appeared to have a tendency to increase. Performing polynomial regression analysis, a significant parabolic correlation was found between LVET/PEP and serum $ T_{4} $ or $ T_{3} $(p < 0.0001). From these results, it might be concluded that large amounts of thyroid hormones suppress cardiac performance. © Italian Society of Endocrinology (SIE) 1981 |
| collection_details |
GBV_USEFLAG_A SYSFLAG_A GBV_SPRINGER SSG-OLC-PHA GBV_ILN_702 GBV_ILN_2190 |
| container_issue |
3 |
| title_short |
The diminished cardiac performance in severe thyrotoxicosis. Parabolic correlation of LVET/PEP to the circulating levels of thyroid hormones |
| url |
https://dx.doi.org/10.1007/BF03349446 |
| remote_bool |
true |
| author2 |
Kasai, K. Shimoda, S. I. |
| author2Str |
Kasai, K. Shimoda, S. I. |
| ppnlink |
369556267 |
| mediatype_str_mv |
c |
| isOA_txt |
false |
| hochschulschrift_bool |
false |
| doi_str |
10.1007/BF03349446 |
| up_date |
2024-07-03T19:37:25.097Z |
| _version_ |
1803587886882226176 |
| fullrecord_marcxml |
<?xml version="1.0" encoding="UTF-8"?><collection xmlns="http://www.loc.gov/MARC21/slim"><record><leader>01000caa a22002652 4500</leader><controlfield tag="001">SPR036785822</controlfield><controlfield tag="003">DE-627</controlfield><controlfield tag="005">20230519183321.0</controlfield><controlfield tag="007">cr uuu---uuuuu</controlfield><controlfield tag="008">201007s1981 xx |||||o 00| ||eng c</controlfield><datafield tag="024" ind1="7" ind2=" "><subfield code="a">10.1007/BF03349446</subfield><subfield code="2">doi</subfield></datafield><datafield tag="035" ind1=" " ind2=" "><subfield code="a">(DE-627)SPR036785822</subfield></datafield><datafield tag="035" ind1=" " ind2=" "><subfield code="a">(SPR)BF03349446-e</subfield></datafield><datafield tag="040" ind1=" " ind2=" "><subfield code="a">DE-627</subfield><subfield code="b">ger</subfield><subfield code="c">DE-627</subfield><subfield code="e">rakwb</subfield></datafield><datafield tag="041" ind1=" " ind2=" "><subfield code="a">eng</subfield></datafield><datafield tag="100" ind1="1" ind2=" "><subfield code="a">Suzuki, Hitoshi</subfield><subfield code="e">verfasserin</subfield><subfield code="4">aut</subfield></datafield><datafield tag="245" ind1="1" ind2="4"><subfield code="a">The diminished cardiac performance in severe thyrotoxicosis. Parabolic correlation of LVET/PEP to the circulating levels of thyroid hormones</subfield></datafield><datafield tag="264" ind1=" " ind2="1"><subfield code="c">1981</subfield></datafield><datafield tag="336" ind1=" " ind2=" "><subfield code="a">Text</subfield><subfield code="b">txt</subfield><subfield code="2">rdacontent</subfield></datafield><datafield tag="337" ind1=" " ind2=" "><subfield code="a">Computermedien</subfield><subfield code="b">c</subfield><subfield code="2">rdamedia</subfield></datafield><datafield tag="338" ind1=" " ind2=" "><subfield code="a">Online-Ressource</subfield><subfield code="b">cr</subfield><subfield code="2">rdacarrier</subfield></datafield><datafield tag="500" ind1=" " ind2=" "><subfield code="a">© Italian Society of Endocrinology (SIE) 1981</subfield></datafield><datafield tag="520" ind1=" " ind2=" "><subfield code="a">Abstract Fifteen patients with thyrotoxicosis, 8 patients with primary hypothyroidism and 15 normal subjects were studied to assess the correlation between systolic time intervals and serum levels of thyroid hormones. In hypothyroid patients, prolongation of PEPc (corrected pre-ejection period), shortening of LVETc (corrected left ventricular ejection time) and low values of LVET/PEP ratio and cardiac output were improved after restoration of thyroid function. In thyrotoxic patients, shortening of PEPc, high values of LVET/PEP ratio and cardiac output were normalized after correction of thyroid function. As contrasted with these observations, in 5 severely thyrotoxic patients, low values of LVET/PEP ratio and cardiac output for thyrotoxicosis were observed; these were not significantly decreased after antithyroid drug treatment, but appeared to have a tendency to increase. Performing polynomial regression analysis, a significant parabolic correlation was found between LVET/PEP and serum $ T_{4} $ or $ T_{3} $(p < 0.0001). From these results, it might be concluded that large amounts of thyroid hormones suppress cardiac performance.</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Kasai, K.</subfield><subfield code="4">aut</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Shimoda, S. I.</subfield><subfield code="4">aut</subfield></datafield><datafield tag="773" ind1="0" ind2="8"><subfield code="i">Enthalten in</subfield><subfield code="t">Journal of endocrinological investigation</subfield><subfield code="d">[S. l.] : Springer, 1978</subfield><subfield code="g">4(1981), 3 vom: Juli, Seite 289-294</subfield><subfield code="w">(DE-627)369556267</subfield><subfield code="w">(DE-600)2119482-8</subfield><subfield code="x">1720-8386</subfield><subfield code="7">nnns</subfield></datafield><datafield tag="773" ind1="1" ind2="8"><subfield code="g">volume:4</subfield><subfield code="g">year:1981</subfield><subfield code="g">number:3</subfield><subfield code="g">month:07</subfield><subfield code="g">pages:289-294</subfield></datafield><datafield tag="856" ind1="4" ind2="0"><subfield code="u">https://dx.doi.org/10.1007/BF03349446</subfield><subfield code="z">lizenzpflichtig</subfield><subfield code="3">Volltext</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_USEFLAG_A</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">SYSFLAG_A</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_SPRINGER</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">SSG-OLC-PHA</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_702</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_2190</subfield></datafield><datafield tag="951" ind1=" " ind2=" "><subfield code="a">AR</subfield></datafield><datafield tag="952" ind1=" " ind2=" "><subfield code="d">4</subfield><subfield code="j">1981</subfield><subfield code="e">3</subfield><subfield code="c">07</subfield><subfield code="h">289-294</subfield></datafield></record></collection>
|
| score |
7.399996 |