Iodine contamination as a cause of hyperthyroidism or lack of TSH response to TRH stimulation (Results based on a screening investigation)
Abstract The sera of all patients with completely suppressed TSH response to TRH obtained during one year (n = 668), and of those with diminished TSH response (n = 153) were screened for total serum iodine content. The ratio between serum iodine and thyroxine iodine below 1.5 indicates none or only...
Ausführliche Beschreibung
Gespeichert in:
| Autor*in: |
Habermann, J. [verfasserIn] |
|---|
| Format: |
E-Artikel |
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| Sprache: |
Englisch |
| Erschienen: |
1982 |
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| Anmerkung: |
© Italian Society of Endocrinology (SIE) 1982 |
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| Übergeordnetes Werk: |
Enthalten in: Journal of endocrinological investigation - [S. l.] : Springer, 1978, 5(1982), 3 vom: Mai, Seite 153-156 |
|---|---|
| Übergeordnetes Werk: |
volume:5 ; year:1982 ; number:3 ; month:05 ; pages:153-156 |
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| DOI / URN: |
10.1007/BF03349470 |
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| 520 | |a Abstract The sera of all patients with completely suppressed TSH response to TRH obtained during one year (n = 668), and of those with diminished TSH response (n = 153) were screened for total serum iodine content. The ratio between serum iodine and thyroxine iodine below 1.5 indicates none or only a minor degree of iodine contamination, whereas a ratio above 1.5 is a clear index of exogenous iodine contamination. Eighty-four (21.3%) of 395 patients with overt hyperthyroidism were iodine contaminated. No prevalence of hyperthyroidism with hyperthyroxinemia could be detected as compared to $ T_{3} $-hyperthyroidism in the contaminated groups. Surprisingly, the iodine contamination rate was twice as high in 273 patients with suppressed TSH response to TRH but normal thyroid hormone levels and not fully explained thyroidal diseases. A high incidence of multifocal autonomous adenomas of the thyroid is the most probable explanation for the TSH suppression in iodine contaminated patients with normal thyroid hormone levels. | ||
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10.1007/BF03349470 doi (DE-627)SPR036786829 (SPR)BF03349470-e DE-627 ger DE-627 rakwb eng Habermann, J. verfasserin aut Iodine contamination as a cause of hyperthyroidism or lack of TSH response to TRH stimulation (Results based on a screening investigation) 1982 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier © Italian Society of Endocrinology (SIE) 1982 Abstract The sera of all patients with completely suppressed TSH response to TRH obtained during one year (n = 668), and of those with diminished TSH response (n = 153) were screened for total serum iodine content. The ratio between serum iodine and thyroxine iodine below 1.5 indicates none or only a minor degree of iodine contamination, whereas a ratio above 1.5 is a clear index of exogenous iodine contamination. Eighty-four (21.3%) of 395 patients with overt hyperthyroidism were iodine contaminated. No prevalence of hyperthyroidism with hyperthyroxinemia could be detected as compared to $ T_{3} $-hyperthyroidism in the contaminated groups. Surprisingly, the iodine contamination rate was twice as high in 273 patients with suppressed TSH response to TRH but normal thyroid hormone levels and not fully explained thyroidal diseases. A high incidence of multifocal autonomous adenomas of the thyroid is the most probable explanation for the TSH suppression in iodine contaminated patients with normal thyroid hormone levels. Leisner, B. aut Witte, A. aut Pickardt, C. R. aut Scriba, P. C. aut Enthalten in Journal of endocrinological investigation [S. l.] : Springer, 1978 5(1982), 3 vom: Mai, Seite 153-156 (DE-627)369556267 (DE-600)2119482-8 1720-8386 nnns volume:5 year:1982 number:3 month:05 pages:153-156 https://dx.doi.org/10.1007/BF03349470 lizenzpflichtig Volltext GBV_USEFLAG_A SYSFLAG_A GBV_SPRINGER SSG-OLC-PHA GBV_ILN_702 GBV_ILN_2190 AR 5 1982 3 05 153-156 |
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10.1007/BF03349470 doi (DE-627)SPR036786829 (SPR)BF03349470-e DE-627 ger DE-627 rakwb eng Habermann, J. verfasserin aut Iodine contamination as a cause of hyperthyroidism or lack of TSH response to TRH stimulation (Results based on a screening investigation) 1982 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier © Italian Society of Endocrinology (SIE) 1982 Abstract The sera of all patients with completely suppressed TSH response to TRH obtained during one year (n = 668), and of those with diminished TSH response (n = 153) were screened for total serum iodine content. The ratio between serum iodine and thyroxine iodine below 1.5 indicates none or only a minor degree of iodine contamination, whereas a ratio above 1.5 is a clear index of exogenous iodine contamination. Eighty-four (21.3%) of 395 patients with overt hyperthyroidism were iodine contaminated. No prevalence of hyperthyroidism with hyperthyroxinemia could be detected as compared to $ T_{3} $-hyperthyroidism in the contaminated groups. Surprisingly, the iodine contamination rate was twice as high in 273 patients with suppressed TSH response to TRH but normal thyroid hormone levels and not fully explained thyroidal diseases. A high incidence of multifocal autonomous adenomas of the thyroid is the most probable explanation for the TSH suppression in iodine contaminated patients with normal thyroid hormone levels. Leisner, B. aut Witte, A. aut Pickardt, C. R. aut Scriba, P. C. aut Enthalten in Journal of endocrinological investigation [S. l.] : Springer, 1978 5(1982), 3 vom: Mai, Seite 153-156 (DE-627)369556267 (DE-600)2119482-8 1720-8386 nnns volume:5 year:1982 number:3 month:05 pages:153-156 https://dx.doi.org/10.1007/BF03349470 lizenzpflichtig Volltext GBV_USEFLAG_A SYSFLAG_A GBV_SPRINGER SSG-OLC-PHA GBV_ILN_702 GBV_ILN_2190 AR 5 1982 3 05 153-156 |
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10.1007/BF03349470 doi (DE-627)SPR036786829 (SPR)BF03349470-e DE-627 ger DE-627 rakwb eng Habermann, J. verfasserin aut Iodine contamination as a cause of hyperthyroidism or lack of TSH response to TRH stimulation (Results based on a screening investigation) 1982 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier © Italian Society of Endocrinology (SIE) 1982 Abstract The sera of all patients with completely suppressed TSH response to TRH obtained during one year (n = 668), and of those with diminished TSH response (n = 153) were screened for total serum iodine content. The ratio between serum iodine and thyroxine iodine below 1.5 indicates none or only a minor degree of iodine contamination, whereas a ratio above 1.5 is a clear index of exogenous iodine contamination. Eighty-four (21.3%) of 395 patients with overt hyperthyroidism were iodine contaminated. No prevalence of hyperthyroidism with hyperthyroxinemia could be detected as compared to $ T_{3} $-hyperthyroidism in the contaminated groups. Surprisingly, the iodine contamination rate was twice as high in 273 patients with suppressed TSH response to TRH but normal thyroid hormone levels and not fully explained thyroidal diseases. A high incidence of multifocal autonomous adenomas of the thyroid is the most probable explanation for the TSH suppression in iodine contaminated patients with normal thyroid hormone levels. Leisner, B. aut Witte, A. aut Pickardt, C. R. aut Scriba, P. C. aut Enthalten in Journal of endocrinological investigation [S. l.] : Springer, 1978 5(1982), 3 vom: Mai, Seite 153-156 (DE-627)369556267 (DE-600)2119482-8 1720-8386 nnns volume:5 year:1982 number:3 month:05 pages:153-156 https://dx.doi.org/10.1007/BF03349470 lizenzpflichtig Volltext GBV_USEFLAG_A SYSFLAG_A GBV_SPRINGER SSG-OLC-PHA GBV_ILN_702 GBV_ILN_2190 AR 5 1982 3 05 153-156 |
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10.1007/BF03349470 doi (DE-627)SPR036786829 (SPR)BF03349470-e DE-627 ger DE-627 rakwb eng Habermann, J. verfasserin aut Iodine contamination as a cause of hyperthyroidism or lack of TSH response to TRH stimulation (Results based on a screening investigation) 1982 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier © Italian Society of Endocrinology (SIE) 1982 Abstract The sera of all patients with completely suppressed TSH response to TRH obtained during one year (n = 668), and of those with diminished TSH response (n = 153) were screened for total serum iodine content. The ratio between serum iodine and thyroxine iodine below 1.5 indicates none or only a minor degree of iodine contamination, whereas a ratio above 1.5 is a clear index of exogenous iodine contamination. Eighty-four (21.3%) of 395 patients with overt hyperthyroidism were iodine contaminated. No prevalence of hyperthyroidism with hyperthyroxinemia could be detected as compared to $ T_{3} $-hyperthyroidism in the contaminated groups. Surprisingly, the iodine contamination rate was twice as high in 273 patients with suppressed TSH response to TRH but normal thyroid hormone levels and not fully explained thyroidal diseases. A high incidence of multifocal autonomous adenomas of the thyroid is the most probable explanation for the TSH suppression in iodine contaminated patients with normal thyroid hormone levels. Leisner, B. aut Witte, A. aut Pickardt, C. R. aut Scriba, P. C. aut Enthalten in Journal of endocrinological investigation [S. l.] : Springer, 1978 5(1982), 3 vom: Mai, Seite 153-156 (DE-627)369556267 (DE-600)2119482-8 1720-8386 nnns volume:5 year:1982 number:3 month:05 pages:153-156 https://dx.doi.org/10.1007/BF03349470 lizenzpflichtig Volltext GBV_USEFLAG_A SYSFLAG_A GBV_SPRINGER SSG-OLC-PHA GBV_ILN_702 GBV_ILN_2190 AR 5 1982 3 05 153-156 |
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10.1007/BF03349470 doi (DE-627)SPR036786829 (SPR)BF03349470-e DE-627 ger DE-627 rakwb eng Habermann, J. verfasserin aut Iodine contamination as a cause of hyperthyroidism or lack of TSH response to TRH stimulation (Results based on a screening investigation) 1982 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier © Italian Society of Endocrinology (SIE) 1982 Abstract The sera of all patients with completely suppressed TSH response to TRH obtained during one year (n = 668), and of those with diminished TSH response (n = 153) were screened for total serum iodine content. The ratio between serum iodine and thyroxine iodine below 1.5 indicates none or only a minor degree of iodine contamination, whereas a ratio above 1.5 is a clear index of exogenous iodine contamination. Eighty-four (21.3%) of 395 patients with overt hyperthyroidism were iodine contaminated. No prevalence of hyperthyroidism with hyperthyroxinemia could be detected as compared to $ T_{3} $-hyperthyroidism in the contaminated groups. Surprisingly, the iodine contamination rate was twice as high in 273 patients with suppressed TSH response to TRH but normal thyroid hormone levels and not fully explained thyroidal diseases. A high incidence of multifocal autonomous adenomas of the thyroid is the most probable explanation for the TSH suppression in iodine contaminated patients with normal thyroid hormone levels. Leisner, B. aut Witte, A. aut Pickardt, C. R. aut Scriba, P. C. aut Enthalten in Journal of endocrinological investigation [S. l.] : Springer, 1978 5(1982), 3 vom: Mai, Seite 153-156 (DE-627)369556267 (DE-600)2119482-8 1720-8386 nnns volume:5 year:1982 number:3 month:05 pages:153-156 https://dx.doi.org/10.1007/BF03349470 lizenzpflichtig Volltext GBV_USEFLAG_A SYSFLAG_A GBV_SPRINGER SSG-OLC-PHA GBV_ILN_702 GBV_ILN_2190 AR 5 1982 3 05 153-156 |
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Abstract The sera of all patients with completely suppressed TSH response to TRH obtained during one year (n = 668), and of those with diminished TSH response (n = 153) were screened for total serum iodine content. The ratio between serum iodine and thyroxine iodine below 1.5 indicates none or only a minor degree of iodine contamination, whereas a ratio above 1.5 is a clear index of exogenous iodine contamination. Eighty-four (21.3%) of 395 patients with overt hyperthyroidism were iodine contaminated. No prevalence of hyperthyroidism with hyperthyroxinemia could be detected as compared to $ T_{3} $-hyperthyroidism in the contaminated groups. Surprisingly, the iodine contamination rate was twice as high in 273 patients with suppressed TSH response to TRH but normal thyroid hormone levels and not fully explained thyroidal diseases. A high incidence of multifocal autonomous adenomas of the thyroid is the most probable explanation for the TSH suppression in iodine contaminated patients with normal thyroid hormone levels. © Italian Society of Endocrinology (SIE) 1982 |
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Abstract The sera of all patients with completely suppressed TSH response to TRH obtained during one year (n = 668), and of those with diminished TSH response (n = 153) were screened for total serum iodine content. The ratio between serum iodine and thyroxine iodine below 1.5 indicates none or only a minor degree of iodine contamination, whereas a ratio above 1.5 is a clear index of exogenous iodine contamination. Eighty-four (21.3%) of 395 patients with overt hyperthyroidism were iodine contaminated. No prevalence of hyperthyroidism with hyperthyroxinemia could be detected as compared to $ T_{3} $-hyperthyroidism in the contaminated groups. Surprisingly, the iodine contamination rate was twice as high in 273 patients with suppressed TSH response to TRH but normal thyroid hormone levels and not fully explained thyroidal diseases. A high incidence of multifocal autonomous adenomas of the thyroid is the most probable explanation for the TSH suppression in iodine contaminated patients with normal thyroid hormone levels. © Italian Society of Endocrinology (SIE) 1982 |
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Abstract The sera of all patients with completely suppressed TSH response to TRH obtained during one year (n = 668), and of those with diminished TSH response (n = 153) were screened for total serum iodine content. The ratio between serum iodine and thyroxine iodine below 1.5 indicates none or only a minor degree of iodine contamination, whereas a ratio above 1.5 is a clear index of exogenous iodine contamination. Eighty-four (21.3%) of 395 patients with overt hyperthyroidism were iodine contaminated. No prevalence of hyperthyroidism with hyperthyroxinemia could be detected as compared to $ T_{3} $-hyperthyroidism in the contaminated groups. Surprisingly, the iodine contamination rate was twice as high in 273 patients with suppressed TSH response to TRH but normal thyroid hormone levels and not fully explained thyroidal diseases. A high incidence of multifocal autonomous adenomas of the thyroid is the most probable explanation for the TSH suppression in iodine contaminated patients with normal thyroid hormone levels. © Italian Society of Endocrinology (SIE) 1982 |
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<?xml version="1.0" encoding="UTF-8"?><collection xmlns="http://www.loc.gov/MARC21/slim"><record><leader>01000caa a22002652 4500</leader><controlfield tag="001">SPR036786829</controlfield><controlfield tag="003">DE-627</controlfield><controlfield tag="005">20230519183322.0</controlfield><controlfield tag="007">cr uuu---uuuuu</controlfield><controlfield tag="008">201007s1982 xx |||||o 00| ||eng c</controlfield><datafield tag="024" ind1="7" ind2=" "><subfield code="a">10.1007/BF03349470</subfield><subfield code="2">doi</subfield></datafield><datafield tag="035" ind1=" " ind2=" "><subfield code="a">(DE-627)SPR036786829</subfield></datafield><datafield tag="035" ind1=" " ind2=" "><subfield code="a">(SPR)BF03349470-e</subfield></datafield><datafield tag="040" ind1=" " ind2=" "><subfield code="a">DE-627</subfield><subfield code="b">ger</subfield><subfield code="c">DE-627</subfield><subfield code="e">rakwb</subfield></datafield><datafield tag="041" ind1=" " ind2=" "><subfield code="a">eng</subfield></datafield><datafield tag="100" ind1="1" ind2=" "><subfield code="a">Habermann, J.</subfield><subfield code="e">verfasserin</subfield><subfield code="4">aut</subfield></datafield><datafield tag="245" ind1="1" ind2="0"><subfield code="a">Iodine contamination as a cause of hyperthyroidism or lack of TSH response to TRH stimulation (Results based on a screening investigation)</subfield></datafield><datafield tag="264" ind1=" " ind2="1"><subfield code="c">1982</subfield></datafield><datafield tag="336" ind1=" " ind2=" "><subfield code="a">Text</subfield><subfield code="b">txt</subfield><subfield code="2">rdacontent</subfield></datafield><datafield tag="337" ind1=" " ind2=" "><subfield code="a">Computermedien</subfield><subfield code="b">c</subfield><subfield code="2">rdamedia</subfield></datafield><datafield tag="338" ind1=" " ind2=" "><subfield code="a">Online-Ressource</subfield><subfield code="b">cr</subfield><subfield code="2">rdacarrier</subfield></datafield><datafield tag="500" ind1=" " ind2=" "><subfield code="a">© Italian Society of Endocrinology (SIE) 1982</subfield></datafield><datafield tag="520" ind1=" " ind2=" "><subfield code="a">Abstract The sera of all patients with completely suppressed TSH response to TRH obtained during one year (n = 668), and of those with diminished TSH response (n = 153) were screened for total serum iodine content. The ratio between serum iodine and thyroxine iodine below 1.5 indicates none or only a minor degree of iodine contamination, whereas a ratio above 1.5 is a clear index of exogenous iodine contamination. Eighty-four (21.3%) of 395 patients with overt hyperthyroidism were iodine contaminated. No prevalence of hyperthyroidism with hyperthyroxinemia could be detected as compared to $ T_{3} $-hyperthyroidism in the contaminated groups. Surprisingly, the iodine contamination rate was twice as high in 273 patients with suppressed TSH response to TRH but normal thyroid hormone levels and not fully explained thyroidal diseases. A high incidence of multifocal autonomous adenomas of the thyroid is the most probable explanation for the TSH suppression in iodine contaminated patients with normal thyroid hormone levels.</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Leisner, B.</subfield><subfield code="4">aut</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Witte, A.</subfield><subfield code="4">aut</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Pickardt, C. R.</subfield><subfield code="4">aut</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Scriba, P. C.</subfield><subfield code="4">aut</subfield></datafield><datafield tag="773" ind1="0" ind2="8"><subfield code="i">Enthalten in</subfield><subfield code="t">Journal of endocrinological investigation</subfield><subfield code="d">[S. l.] : Springer, 1978</subfield><subfield code="g">5(1982), 3 vom: Mai, Seite 153-156</subfield><subfield code="w">(DE-627)369556267</subfield><subfield code="w">(DE-600)2119482-8</subfield><subfield code="x">1720-8386</subfield><subfield code="7">nnns</subfield></datafield><datafield tag="773" ind1="1" ind2="8"><subfield code="g">volume:5</subfield><subfield code="g">year:1982</subfield><subfield code="g">number:3</subfield><subfield code="g">month:05</subfield><subfield code="g">pages:153-156</subfield></datafield><datafield tag="856" ind1="4" ind2="0"><subfield code="u">https://dx.doi.org/10.1007/BF03349470</subfield><subfield code="z">lizenzpflichtig</subfield><subfield code="3">Volltext</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_USEFLAG_A</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">SYSFLAG_A</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_SPRINGER</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">SSG-OLC-PHA</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_702</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_2190</subfield></datafield><datafield tag="951" ind1=" " ind2=" "><subfield code="a">AR</subfield></datafield><datafield tag="952" ind1=" " ind2=" "><subfield code="d">5</subfield><subfield code="j">1982</subfield><subfield code="e">3</subfield><subfield code="c">05</subfield><subfield code="h">153-156</subfield></datafield></record></collection>
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