Intrahepatic cholangiocarcinoma in a patient with Wilson’s disease: a case report

Abstract The incidence of hepatobiliary malignancies, and especially intrahepatic cholangiocarcinoma (ICC), for patients with Wilson’s disease (WD), is very low, even for cirrhotic patients. A 44-year-old male was admitted to our department for treatment of a liver tumor. He was diagnosed with WD at...
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Autor*in:	Mukai, Yosuke [verfasserIn] Wada, Hiroshi Eguchi, Hidetoshi Yamada, Daisaku Asaoka, Tadafumi Noda, Takehiro Kawamoto, Koichi Gotoh, Kunihito Takeda, Yutaka Tanemura, Masahiro Umeshita, Koji Hori, Yumiko Morii, Eiichi Doki, Yuichiro Mori, Masaki

Format:	E-Artikel
Sprache:	Englisch

Erschienen:	2016

Schlagwörter:	Wilson’s disease Intrahepatic cholangiocarcinoma Liver tumor Hepatobiliary malignancies

Anmerkung:	© Mukai et al. 2016

Übergeordnetes Werk:	Enthalten in: Surgical case reports - Berlin : SpringerOpen, 2015, 2(2016), 1 vom: 23. März
Übergeordnetes Werk:	volume:2 ; year:2016 ; number:1 ; day:23 ; month:03

Links:	Volltext

DOI / URN:	10.1186/s40792-016-0156-3

Katalog-ID:	SPR037751816

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520			\|a Abstract The incidence of hepatobiliary malignancies, and especially intrahepatic cholangiocarcinoma (ICC), for patients with Wilson’s disease (WD), is very low, even for cirrhotic patients. A 44-year-old male was admitted to our department for treatment of a liver tumor. He was diagnosed with WD at the age of 15. According to radiological findings, his liver tumor was a suspected hepatocellular carcinoma (HCC) or a combined hepatocellular and cholangiocellular carcinoma. A partial resection of liver segments 8 (S8) and 5 (S5) was subsequently performed due to the intraoperative suspicion of intrahepatic metastasis at the surface of S5. Postoperative histology revealed that the resected portion of S8 contained an ICC; the removed S5 portion comprised a regenerative nodule with hemosiderosis. To date, the patient has survived without tumor recurrence for more than 44 months following surgery. A survey of the literature, inclusive of case reports, would suggest that surgical resection is the primary course of action for a WD patient with ICC, if liver function can be preserved and curative resection performed.
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allfields	10.1186/s40792-016-0156-3 doi (DE-627)SPR037751816 (SPR)s40792-016-0156-3-e DE-627 ger DE-627 rakwb eng Mukai, Yosuke verfasserin aut Intrahepatic cholangiocarcinoma in a patient with Wilson’s disease: a case report 2016 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier © Mukai et al. 2016 Abstract The incidence of hepatobiliary malignancies, and especially intrahepatic cholangiocarcinoma (ICC), for patients with Wilson’s disease (WD), is very low, even for cirrhotic patients. A 44-year-old male was admitted to our department for treatment of a liver tumor. He was diagnosed with WD at the age of 15. According to radiological findings, his liver tumor was a suspected hepatocellular carcinoma (HCC) or a combined hepatocellular and cholangiocellular carcinoma. A partial resection of liver segments 8 (S8) and 5 (S5) was subsequently performed due to the intraoperative suspicion of intrahepatic metastasis at the surface of S5. Postoperative histology revealed that the resected portion of S8 contained an ICC; the removed S5 portion comprised a regenerative nodule with hemosiderosis. To date, the patient has survived without tumor recurrence for more than 44 months following surgery. A survey of the literature, inclusive of case reports, would suggest that surgical resection is the primary course of action for a WD patient with ICC, if liver function can be preserved and curative resection performed. Wilson’s disease (dpeaa)DE-He213 Intrahepatic cholangiocarcinoma (dpeaa)DE-He213 Liver tumor (dpeaa)DE-He213 Hepatobiliary malignancies (dpeaa)DE-He213 Wada, Hiroshi aut Eguchi, Hidetoshi aut Yamada, Daisaku aut Asaoka, Tadafumi aut Noda, Takehiro aut Kawamoto, Koichi aut Gotoh, Kunihito aut Takeda, Yutaka aut Tanemura, Masahiro aut Umeshita, Koji aut Hori, Yumiko aut Morii, Eiichi aut Doki, Yuichiro aut Mori, Masaki aut Enthalten in Surgical case reports Berlin : SpringerOpen, 2015 2(2016), 1 vom: 23. März (DE-627)818040475 (DE-600)2809613-7 2198-7793 nnns volume:2 year:2016 number:1 day:23 month:03 https://dx.doi.org/10.1186/s40792-016-0156-3 kostenfrei Volltext GBV_USEFLAG_A SYSFLAG_A GBV_SPRINGER SSG-OLC-PHA GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_2014 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 2 2016 1 23 03
spelling	10.1186/s40792-016-0156-3 doi (DE-627)SPR037751816 (SPR)s40792-016-0156-3-e DE-627 ger DE-627 rakwb eng Mukai, Yosuke verfasserin aut Intrahepatic cholangiocarcinoma in a patient with Wilson’s disease: a case report 2016 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier © Mukai et al. 2016 Abstract The incidence of hepatobiliary malignancies, and especially intrahepatic cholangiocarcinoma (ICC), for patients with Wilson’s disease (WD), is very low, even for cirrhotic patients. A 44-year-old male was admitted to our department for treatment of a liver tumor. He was diagnosed with WD at the age of 15. According to radiological findings, his liver tumor was a suspected hepatocellular carcinoma (HCC) or a combined hepatocellular and cholangiocellular carcinoma. A partial resection of liver segments 8 (S8) and 5 (S5) was subsequently performed due to the intraoperative suspicion of intrahepatic metastasis at the surface of S5. Postoperative histology revealed that the resected portion of S8 contained an ICC; the removed S5 portion comprised a regenerative nodule with hemosiderosis. To date, the patient has survived without tumor recurrence for more than 44 months following surgery. A survey of the literature, inclusive of case reports, would suggest that surgical resection is the primary course of action for a WD patient with ICC, if liver function can be preserved and curative resection performed. Wilson’s disease (dpeaa)DE-He213 Intrahepatic cholangiocarcinoma (dpeaa)DE-He213 Liver tumor (dpeaa)DE-He213 Hepatobiliary malignancies (dpeaa)DE-He213 Wada, Hiroshi aut Eguchi, Hidetoshi aut Yamada, Daisaku aut Asaoka, Tadafumi aut Noda, Takehiro aut Kawamoto, Koichi aut Gotoh, Kunihito aut Takeda, Yutaka aut Tanemura, Masahiro aut Umeshita, Koji aut Hori, Yumiko aut Morii, Eiichi aut Doki, Yuichiro aut Mori, Masaki aut Enthalten in Surgical case reports Berlin : SpringerOpen, 2015 2(2016), 1 vom: 23. März (DE-627)818040475 (DE-600)2809613-7 2198-7793 nnns volume:2 year:2016 number:1 day:23 month:03 https://dx.doi.org/10.1186/s40792-016-0156-3 kostenfrei Volltext GBV_USEFLAG_A SYSFLAG_A GBV_SPRINGER SSG-OLC-PHA GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_2014 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 2 2016 1 23 03
allfields_unstemmed	10.1186/s40792-016-0156-3 doi (DE-627)SPR037751816 (SPR)s40792-016-0156-3-e DE-627 ger DE-627 rakwb eng Mukai, Yosuke verfasserin aut Intrahepatic cholangiocarcinoma in a patient with Wilson’s disease: a case report 2016 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier © Mukai et al. 2016 Abstract The incidence of hepatobiliary malignancies, and especially intrahepatic cholangiocarcinoma (ICC), for patients with Wilson’s disease (WD), is very low, even for cirrhotic patients. A 44-year-old male was admitted to our department for treatment of a liver tumor. He was diagnosed with WD at the age of 15. According to radiological findings, his liver tumor was a suspected hepatocellular carcinoma (HCC) or a combined hepatocellular and cholangiocellular carcinoma. A partial resection of liver segments 8 (S8) and 5 (S5) was subsequently performed due to the intraoperative suspicion of intrahepatic metastasis at the surface of S5. Postoperative histology revealed that the resected portion of S8 contained an ICC; the removed S5 portion comprised a regenerative nodule with hemosiderosis. To date, the patient has survived without tumor recurrence for more than 44 months following surgery. A survey of the literature, inclusive of case reports, would suggest that surgical resection is the primary course of action for a WD patient with ICC, if liver function can be preserved and curative resection performed. Wilson’s disease (dpeaa)DE-He213 Intrahepatic cholangiocarcinoma (dpeaa)DE-He213 Liver tumor (dpeaa)DE-He213 Hepatobiliary malignancies (dpeaa)DE-He213 Wada, Hiroshi aut Eguchi, Hidetoshi aut Yamada, Daisaku aut Asaoka, Tadafumi aut Noda, Takehiro aut Kawamoto, Koichi aut Gotoh, Kunihito aut Takeda, Yutaka aut Tanemura, Masahiro aut Umeshita, Koji aut Hori, Yumiko aut Morii, Eiichi aut Doki, Yuichiro aut Mori, Masaki aut Enthalten in Surgical case reports Berlin : SpringerOpen, 2015 2(2016), 1 vom: 23. März (DE-627)818040475 (DE-600)2809613-7 2198-7793 nnns volume:2 year:2016 number:1 day:23 month:03 https://dx.doi.org/10.1186/s40792-016-0156-3 kostenfrei Volltext GBV_USEFLAG_A SYSFLAG_A GBV_SPRINGER SSG-OLC-PHA GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_2014 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 2 2016 1 23 03
allfieldsGer	10.1186/s40792-016-0156-3 doi (DE-627)SPR037751816 (SPR)s40792-016-0156-3-e DE-627 ger DE-627 rakwb eng Mukai, Yosuke verfasserin aut Intrahepatic cholangiocarcinoma in a patient with Wilson’s disease: a case report 2016 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier © Mukai et al. 2016 Abstract The incidence of hepatobiliary malignancies, and especially intrahepatic cholangiocarcinoma (ICC), for patients with Wilson’s disease (WD), is very low, even for cirrhotic patients. A 44-year-old male was admitted to our department for treatment of a liver tumor. He was diagnosed with WD at the age of 15. According to radiological findings, his liver tumor was a suspected hepatocellular carcinoma (HCC) or a combined hepatocellular and cholangiocellular carcinoma. A partial resection of liver segments 8 (S8) and 5 (S5) was subsequently performed due to the intraoperative suspicion of intrahepatic metastasis at the surface of S5. Postoperative histology revealed that the resected portion of S8 contained an ICC; the removed S5 portion comprised a regenerative nodule with hemosiderosis. To date, the patient has survived without tumor recurrence for more than 44 months following surgery. A survey of the literature, inclusive of case reports, would suggest that surgical resection is the primary course of action for a WD patient with ICC, if liver function can be preserved and curative resection performed. Wilson’s disease (dpeaa)DE-He213 Intrahepatic cholangiocarcinoma (dpeaa)DE-He213 Liver tumor (dpeaa)DE-He213 Hepatobiliary malignancies (dpeaa)DE-He213 Wada, Hiroshi aut Eguchi, Hidetoshi aut Yamada, Daisaku aut Asaoka, Tadafumi aut Noda, Takehiro aut Kawamoto, Koichi aut Gotoh, Kunihito aut Takeda, Yutaka aut Tanemura, Masahiro aut Umeshita, Koji aut Hori, Yumiko aut Morii, Eiichi aut Doki, Yuichiro aut Mori, Masaki aut Enthalten in Surgical case reports Berlin : SpringerOpen, 2015 2(2016), 1 vom: 23. März (DE-627)818040475 (DE-600)2809613-7 2198-7793 nnns volume:2 year:2016 number:1 day:23 month:03 https://dx.doi.org/10.1186/s40792-016-0156-3 kostenfrei Volltext GBV_USEFLAG_A SYSFLAG_A GBV_SPRINGER SSG-OLC-PHA GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_2014 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 2 2016 1 23 03
allfieldsSound	10.1186/s40792-016-0156-3 doi (DE-627)SPR037751816 (SPR)s40792-016-0156-3-e DE-627 ger DE-627 rakwb eng Mukai, Yosuke verfasserin aut Intrahepatic cholangiocarcinoma in a patient with Wilson’s disease: a case report 2016 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier © Mukai et al. 2016 Abstract The incidence of hepatobiliary malignancies, and especially intrahepatic cholangiocarcinoma (ICC), for patients with Wilson’s disease (WD), is very low, even for cirrhotic patients. A 44-year-old male was admitted to our department for treatment of a liver tumor. He was diagnosed with WD at the age of 15. According to radiological findings, his liver tumor was a suspected hepatocellular carcinoma (HCC) or a combined hepatocellular and cholangiocellular carcinoma. A partial resection of liver segments 8 (S8) and 5 (S5) was subsequently performed due to the intraoperative suspicion of intrahepatic metastasis at the surface of S5. Postoperative histology revealed that the resected portion of S8 contained an ICC; the removed S5 portion comprised a regenerative nodule with hemosiderosis. To date, the patient has survived without tumor recurrence for more than 44 months following surgery. A survey of the literature, inclusive of case reports, would suggest that surgical resection is the primary course of action for a WD patient with ICC, if liver function can be preserved and curative resection performed. Wilson’s disease (dpeaa)DE-He213 Intrahepatic cholangiocarcinoma (dpeaa)DE-He213 Liver tumor (dpeaa)DE-He213 Hepatobiliary malignancies (dpeaa)DE-He213 Wada, Hiroshi aut Eguchi, Hidetoshi aut Yamada, Daisaku aut Asaoka, Tadafumi aut Noda, Takehiro aut Kawamoto, Koichi aut Gotoh, Kunihito aut Takeda, Yutaka aut Tanemura, Masahiro aut Umeshita, Koji aut Hori, Yumiko aut Morii, Eiichi aut Doki, Yuichiro aut Mori, Masaki aut Enthalten in Surgical case reports Berlin : SpringerOpen, 2015 2(2016), 1 vom: 23. März (DE-627)818040475 (DE-600)2809613-7 2198-7793 nnns volume:2 year:2016 number:1 day:23 month:03 https://dx.doi.org/10.1186/s40792-016-0156-3 kostenfrei Volltext GBV_USEFLAG_A SYSFLAG_A GBV_SPRINGER SSG-OLC-PHA GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_2014 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 2 2016 1 23 03
language	English
source	Enthalten in Surgical case reports 2(2016), 1 vom: 23. März volume:2 year:2016 number:1 day:23 month:03
sourceStr	Enthalten in Surgical case reports 2(2016), 1 vom: 23. März volume:2 year:2016 number:1 day:23 month:03
format_phy_str_mv	Article
institution	findex.gbv.de
topic_facet	Wilson’s disease Intrahepatic cholangiocarcinoma Liver tumor Hepatobiliary malignancies
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container_title	Surgical case reports
authorswithroles_txt_mv	Mukai, Yosuke @@aut@@ Wada, Hiroshi @@aut@@ Eguchi, Hidetoshi @@aut@@ Yamada, Daisaku @@aut@@ Asaoka, Tadafumi @@aut@@ Noda, Takehiro @@aut@@ Kawamoto, Koichi @@aut@@ Gotoh, Kunihito @@aut@@ Takeda, Yutaka @@aut@@ Tanemura, Masahiro @@aut@@ Umeshita, Koji @@aut@@ Hori, Yumiko @@aut@@ Morii, Eiichi @@aut@@ Doki, Yuichiro @@aut@@ Mori, Masaki @@aut@@
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author	Mukai, Yosuke
spellingShingle	Mukai, Yosuke misc Wilson’s disease misc Intrahepatic cholangiocarcinoma misc Liver tumor misc Hepatobiliary malignancies Intrahepatic cholangiocarcinoma in a patient with Wilson’s disease: a case report
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topic_title	Intrahepatic cholangiocarcinoma in a patient with Wilson’s disease: a case report Wilson’s disease (dpeaa)DE-He213 Intrahepatic cholangiocarcinoma (dpeaa)DE-He213 Liver tumor (dpeaa)DE-He213 Hepatobiliary malignancies (dpeaa)DE-He213
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title	Intrahepatic cholangiocarcinoma in a patient with Wilson’s disease: a case report
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title_full	Intrahepatic cholangiocarcinoma in a patient with Wilson’s disease: a case report
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author_browse	Mukai, Yosuke Wada, Hiroshi Eguchi, Hidetoshi Yamada, Daisaku Asaoka, Tadafumi Noda, Takehiro Kawamoto, Koichi Gotoh, Kunihito Takeda, Yutaka Tanemura, Masahiro Umeshita, Koji Hori, Yumiko Morii, Eiichi Doki, Yuichiro Mori, Masaki
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title_sort	intrahepatic cholangiocarcinoma in a patient with wilson’s disease: a case report
title_auth	Intrahepatic cholangiocarcinoma in a patient with Wilson’s disease: a case report
abstract	Abstract The incidence of hepatobiliary malignancies, and especially intrahepatic cholangiocarcinoma (ICC), for patients with Wilson’s disease (WD), is very low, even for cirrhotic patients. A 44-year-old male was admitted to our department for treatment of a liver tumor. He was diagnosed with WD at the age of 15. According to radiological findings, his liver tumor was a suspected hepatocellular carcinoma (HCC) or a combined hepatocellular and cholangiocellular carcinoma. A partial resection of liver segments 8 (S8) and 5 (S5) was subsequently performed due to the intraoperative suspicion of intrahepatic metastasis at the surface of S5. Postoperative histology revealed that the resected portion of S8 contained an ICC; the removed S5 portion comprised a regenerative nodule with hemosiderosis. To date, the patient has survived without tumor recurrence for more than 44 months following surgery. A survey of the literature, inclusive of case reports, would suggest that surgical resection is the primary course of action for a WD patient with ICC, if liver function can be preserved and curative resection performed. © Mukai et al. 2016
abstractGer	Abstract The incidence of hepatobiliary malignancies, and especially intrahepatic cholangiocarcinoma (ICC), for patients with Wilson’s disease (WD), is very low, even for cirrhotic patients. A 44-year-old male was admitted to our department for treatment of a liver tumor. He was diagnosed with WD at the age of 15. According to radiological findings, his liver tumor was a suspected hepatocellular carcinoma (HCC) or a combined hepatocellular and cholangiocellular carcinoma. A partial resection of liver segments 8 (S8) and 5 (S5) was subsequently performed due to the intraoperative suspicion of intrahepatic metastasis at the surface of S5. Postoperative histology revealed that the resected portion of S8 contained an ICC; the removed S5 portion comprised a regenerative nodule with hemosiderosis. To date, the patient has survived without tumor recurrence for more than 44 months following surgery. A survey of the literature, inclusive of case reports, would suggest that surgical resection is the primary course of action for a WD patient with ICC, if liver function can be preserved and curative resection performed. © Mukai et al. 2016
abstract_unstemmed	Abstract The incidence of hepatobiliary malignancies, and especially intrahepatic cholangiocarcinoma (ICC), for patients with Wilson’s disease (WD), is very low, even for cirrhotic patients. A 44-year-old male was admitted to our department for treatment of a liver tumor. He was diagnosed with WD at the age of 15. According to radiological findings, his liver tumor was a suspected hepatocellular carcinoma (HCC) or a combined hepatocellular and cholangiocellular carcinoma. A partial resection of liver segments 8 (S8) and 5 (S5) was subsequently performed due to the intraoperative suspicion of intrahepatic metastasis at the surface of S5. Postoperative histology revealed that the resected portion of S8 contained an ICC; the removed S5 portion comprised a regenerative nodule with hemosiderosis. To date, the patient has survived without tumor recurrence for more than 44 months following surgery. A survey of the literature, inclusive of case reports, would suggest that surgical resection is the primary course of action for a WD patient with ICC, if liver function can be preserved and curative resection performed. © Mukai et al. 2016
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title_short	Intrahepatic cholangiocarcinoma in a patient with Wilson’s disease: a case report
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A 44-year-old male was admitted to our department for treatment of a liver tumor. He was diagnosed with WD at the age of 15. According to radiological findings, his liver tumor was a suspected hepatocellular carcinoma (HCC) or a combined hepatocellular and cholangiocellular carcinoma. A partial resection of liver segments 8 (S8) and 5 (S5) was subsequently performed due to the intraoperative suspicion of intrahepatic metastasis at the surface of S5. Postoperative histology revealed that the resected portion of S8 contained an ICC; the removed S5 portion comprised a regenerative nodule with hemosiderosis. To date, the patient has survived without tumor recurrence for more than 44 months following surgery. 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Intrahepatic cholangiocarcinoma in a patient with Wilson’s disease: a case report

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