Prevalence of Drug-Related Emergency Department Visits at a Teaching Hospital in Malaysia

Background Data on the prevalence of adverse drug event (ADE)-related emergency department (ED) visits in developing countries are limited. Malaysia is located in South-East Asia, and, to our knowledge, no information exists on ADE-related ED visits. Objective The objective of this study was to dete...
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Autor*in:	Jatau, Abubakar Ibrahim [verfasserIn] Aung, Myat Moe Thwe Kamauzaman, Tuan Hairulnizam Tuan Rahman, Ab Fatah Ab

Format:	E-Artikel
Sprache:	Englisch

Erschienen:	2015

Schlagwörter:	Emergency Department Emergency Department Visit Adverse Drug Event Gliclazide Emergency Department Physician

Anmerkung:	© The Author(s) 2015

Übergeordnetes Werk:	Enthalten in: Drugs - real world outcomes - New York, NY [u.a.] : SpringerOpen, 2014, 2(2015), 4 vom: 23. Okt., Seite 387-395
Übergeordnetes Werk:	volume:2 ; year:2015 ; number:4 ; day:23 ; month:10 ; pages:387-395

Links:	Volltext

DOI / URN:	10.1007/s40801-015-0045-2

Katalog-ID:	SPR03781365X

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520			\|a Background Data on the prevalence of adverse drug event (ADE)-related emergency department (ED) visits in developing countries are limited. Malaysia is located in South-East Asia, and, to our knowledge, no information exists on ADE-related ED visits. Objective The objective of this study was to determine the prevalence, preventability, severity, and outcome of drug-related ED visits. Methodology A cross-sectional study was conducted in consenting patients who visited the ED of Hospital Universiti Sains Malaysia over a 6-week period. The ED physician on duty determined whether or not the visit was drug related according to set criteria. Other relevant information was extracted from the patient’s medical folder by a clinical pharmacist. Results Of the 434 consenting patients, 133 (30.6 %; 95 % confidence interval [CI] 26–35 %) visits were determined to be ADE related; 55.5 % were considered preventable, 11.3 % possibly preventable, and 33.1 % not preventable. Severity was classed as mild in 1.5 %, moderate in 67.7 %, and severe in 30.8 %. The most common ADEs reported were drug therapeutic failure (55.6 %) and adverse drug reactions (32.3 %). The most frequently implicated drugs were antidiabetics (n = 31; 23.3 %), antihypertensives (n = 28; 21.1 %), antibiotics (n = 13; 9.8 %), and anti-asthmatics (n = 11; 8.3 %). A total of 93 patients (69.9 %) were admitted to the ED for observation, 25 (18.8 %) were discharged immediately after consultation, and 15 (11.3 %) were admitted to the ward through the ED. Conclusion The prevalence of ADE-related ED visits was high; more than one-half of the events were considered preventable and one-third was classed as severe. As such, preventive measures will minimize future occurrences and increase patient safety.
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allfields	10.1007/s40801-015-0045-2 doi (DE-627)SPR03781365X (SPR)s40801-015-0045-2-e DE-627 ger DE-627 rakwb eng Jatau, Abubakar Ibrahim verfasserin aut Prevalence of Drug-Related Emergency Department Visits at a Teaching Hospital in Malaysia 2015 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier © The Author(s) 2015 Background Data on the prevalence of adverse drug event (ADE)-related emergency department (ED) visits in developing countries are limited. Malaysia is located in South-East Asia, and, to our knowledge, no information exists on ADE-related ED visits. Objective The objective of this study was to determine the prevalence, preventability, severity, and outcome of drug-related ED visits. Methodology A cross-sectional study was conducted in consenting patients who visited the ED of Hospital Universiti Sains Malaysia over a 6-week period. The ED physician on duty determined whether or not the visit was drug related according to set criteria. Other relevant information was extracted from the patient’s medical folder by a clinical pharmacist. Results Of the 434 consenting patients, 133 (30.6 %; 95 % confidence interval [CI] 26–35 %) visits were determined to be ADE related; 55.5 % were considered preventable, 11.3 % possibly preventable, and 33.1 % not preventable. Severity was classed as mild in 1.5 %, moderate in 67.7 %, and severe in 30.8 %. The most common ADEs reported were drug therapeutic failure (55.6 %) and adverse drug reactions (32.3 %). The most frequently implicated drugs were antidiabetics (n = 31; 23.3 %), antihypertensives (n = 28; 21.1 %), antibiotics (n = 13; 9.8 %), and anti-asthmatics (n = 11; 8.3 %). A total of 93 patients (69.9 %) were admitted to the ED for observation, 25 (18.8 %) were discharged immediately after consultation, and 15 (11.3 %) were admitted to the ward through the ED. Conclusion The prevalence of ADE-related ED visits was high; more than one-half of the events were considered preventable and one-third was classed as severe. As such, preventive measures will minimize future occurrences and increase patient safety. Emergency Department (dpeaa)DE-He213 Emergency Department Visit (dpeaa)DE-He213 Adverse Drug Event (dpeaa)DE-He213 Gliclazide (dpeaa)DE-He213 Emergency Department Physician (dpeaa)DE-He213 Aung, Myat Moe Thwe aut Kamauzaman, Tuan Hairulnizam Tuan aut Rahman, Ab Fatah Ab aut Enthalten in Drugs - real world outcomes New York, NY [u.a.] : SpringerOpen, 2014 2(2015), 4 vom: 23. Okt., Seite 387-395 (DE-627)815914024 (DE-600)2806600-5 2198-9788 nnns volume:2 year:2015 number:4 day:23 month:10 pages:387-395 https://dx.doi.org/10.1007/s40801-015-0045-2 kostenfrei Volltext GBV_USEFLAG_A SYSFLAG_A GBV_SPRINGER SSG-OLC-PHA GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_70 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_2009 GBV_ILN_2014 GBV_ILN_2111 GBV_ILN_2129 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4046 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 2 2015 4 23 10 387-395
spelling	10.1007/s40801-015-0045-2 doi (DE-627)SPR03781365X (SPR)s40801-015-0045-2-e DE-627 ger DE-627 rakwb eng Jatau, Abubakar Ibrahim verfasserin aut Prevalence of Drug-Related Emergency Department Visits at a Teaching Hospital in Malaysia 2015 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier © The Author(s) 2015 Background Data on the prevalence of adverse drug event (ADE)-related emergency department (ED) visits in developing countries are limited. Malaysia is located in South-East Asia, and, to our knowledge, no information exists on ADE-related ED visits. Objective The objective of this study was to determine the prevalence, preventability, severity, and outcome of drug-related ED visits. Methodology A cross-sectional study was conducted in consenting patients who visited the ED of Hospital Universiti Sains Malaysia over a 6-week period. The ED physician on duty determined whether or not the visit was drug related according to set criteria. Other relevant information was extracted from the patient’s medical folder by a clinical pharmacist. Results Of the 434 consenting patients, 133 (30.6 %; 95 % confidence interval [CI] 26–35 %) visits were determined to be ADE related; 55.5 % were considered preventable, 11.3 % possibly preventable, and 33.1 % not preventable. Severity was classed as mild in 1.5 %, moderate in 67.7 %, and severe in 30.8 %. The most common ADEs reported were drug therapeutic failure (55.6 %) and adverse drug reactions (32.3 %). The most frequently implicated drugs were antidiabetics (n = 31; 23.3 %), antihypertensives (n = 28; 21.1 %), antibiotics (n = 13; 9.8 %), and anti-asthmatics (n = 11; 8.3 %). A total of 93 patients (69.9 %) were admitted to the ED for observation, 25 (18.8 %) were discharged immediately after consultation, and 15 (11.3 %) were admitted to the ward through the ED. Conclusion The prevalence of ADE-related ED visits was high; more than one-half of the events were considered preventable and one-third was classed as severe. As such, preventive measures will minimize future occurrences and increase patient safety. Emergency Department (dpeaa)DE-He213 Emergency Department Visit (dpeaa)DE-He213 Adverse Drug Event (dpeaa)DE-He213 Gliclazide (dpeaa)DE-He213 Emergency Department Physician (dpeaa)DE-He213 Aung, Myat Moe Thwe aut Kamauzaman, Tuan Hairulnizam Tuan aut Rahman, Ab Fatah Ab aut Enthalten in Drugs - real world outcomes New York, NY [u.a.] : SpringerOpen, 2014 2(2015), 4 vom: 23. Okt., Seite 387-395 (DE-627)815914024 (DE-600)2806600-5 2198-9788 nnns volume:2 year:2015 number:4 day:23 month:10 pages:387-395 https://dx.doi.org/10.1007/s40801-015-0045-2 kostenfrei Volltext GBV_USEFLAG_A SYSFLAG_A GBV_SPRINGER SSG-OLC-PHA GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_70 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_2009 GBV_ILN_2014 GBV_ILN_2111 GBV_ILN_2129 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4046 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 2 2015 4 23 10 387-395
allfields_unstemmed	10.1007/s40801-015-0045-2 doi (DE-627)SPR03781365X (SPR)s40801-015-0045-2-e DE-627 ger DE-627 rakwb eng Jatau, Abubakar Ibrahim verfasserin aut Prevalence of Drug-Related Emergency Department Visits at a Teaching Hospital in Malaysia 2015 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier © The Author(s) 2015 Background Data on the prevalence of adverse drug event (ADE)-related emergency department (ED) visits in developing countries are limited. Malaysia is located in South-East Asia, and, to our knowledge, no information exists on ADE-related ED visits. Objective The objective of this study was to determine the prevalence, preventability, severity, and outcome of drug-related ED visits. Methodology A cross-sectional study was conducted in consenting patients who visited the ED of Hospital Universiti Sains Malaysia over a 6-week period. The ED physician on duty determined whether or not the visit was drug related according to set criteria. Other relevant information was extracted from the patient’s medical folder by a clinical pharmacist. Results Of the 434 consenting patients, 133 (30.6 %; 95 % confidence interval [CI] 26–35 %) visits were determined to be ADE related; 55.5 % were considered preventable, 11.3 % possibly preventable, and 33.1 % not preventable. Severity was classed as mild in 1.5 %, moderate in 67.7 %, and severe in 30.8 %. The most common ADEs reported were drug therapeutic failure (55.6 %) and adverse drug reactions (32.3 %). The most frequently implicated drugs were antidiabetics (n = 31; 23.3 %), antihypertensives (n = 28; 21.1 %), antibiotics (n = 13; 9.8 %), and anti-asthmatics (n = 11; 8.3 %). A total of 93 patients (69.9 %) were admitted to the ED for observation, 25 (18.8 %) were discharged immediately after consultation, and 15 (11.3 %) were admitted to the ward through the ED. Conclusion The prevalence of ADE-related ED visits was high; more than one-half of the events were considered preventable and one-third was classed as severe. As such, preventive measures will minimize future occurrences and increase patient safety. Emergency Department (dpeaa)DE-He213 Emergency Department Visit (dpeaa)DE-He213 Adverse Drug Event (dpeaa)DE-He213 Gliclazide (dpeaa)DE-He213 Emergency Department Physician (dpeaa)DE-He213 Aung, Myat Moe Thwe aut Kamauzaman, Tuan Hairulnizam Tuan aut Rahman, Ab Fatah Ab aut Enthalten in Drugs - real world outcomes New York, NY [u.a.] : SpringerOpen, 2014 2(2015), 4 vom: 23. Okt., Seite 387-395 (DE-627)815914024 (DE-600)2806600-5 2198-9788 nnns volume:2 year:2015 number:4 day:23 month:10 pages:387-395 https://dx.doi.org/10.1007/s40801-015-0045-2 kostenfrei Volltext GBV_USEFLAG_A SYSFLAG_A GBV_SPRINGER SSG-OLC-PHA GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_70 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_2009 GBV_ILN_2014 GBV_ILN_2111 GBV_ILN_2129 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4046 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 2 2015 4 23 10 387-395
allfieldsGer	10.1007/s40801-015-0045-2 doi (DE-627)SPR03781365X (SPR)s40801-015-0045-2-e DE-627 ger DE-627 rakwb eng Jatau, Abubakar Ibrahim verfasserin aut Prevalence of Drug-Related Emergency Department Visits at a Teaching Hospital in Malaysia 2015 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier © The Author(s) 2015 Background Data on the prevalence of adverse drug event (ADE)-related emergency department (ED) visits in developing countries are limited. Malaysia is located in South-East Asia, and, to our knowledge, no information exists on ADE-related ED visits. Objective The objective of this study was to determine the prevalence, preventability, severity, and outcome of drug-related ED visits. Methodology A cross-sectional study was conducted in consenting patients who visited the ED of Hospital Universiti Sains Malaysia over a 6-week period. The ED physician on duty determined whether or not the visit was drug related according to set criteria. Other relevant information was extracted from the patient’s medical folder by a clinical pharmacist. Results Of the 434 consenting patients, 133 (30.6 %; 95 % confidence interval [CI] 26–35 %) visits were determined to be ADE related; 55.5 % were considered preventable, 11.3 % possibly preventable, and 33.1 % not preventable. Severity was classed as mild in 1.5 %, moderate in 67.7 %, and severe in 30.8 %. The most common ADEs reported were drug therapeutic failure (55.6 %) and adverse drug reactions (32.3 %). The most frequently implicated drugs were antidiabetics (n = 31; 23.3 %), antihypertensives (n = 28; 21.1 %), antibiotics (n = 13; 9.8 %), and anti-asthmatics (n = 11; 8.3 %). A total of 93 patients (69.9 %) were admitted to the ED for observation, 25 (18.8 %) were discharged immediately after consultation, and 15 (11.3 %) were admitted to the ward through the ED. Conclusion The prevalence of ADE-related ED visits was high; more than one-half of the events were considered preventable and one-third was classed as severe. As such, preventive measures will minimize future occurrences and increase patient safety. Emergency Department (dpeaa)DE-He213 Emergency Department Visit (dpeaa)DE-He213 Adverse Drug Event (dpeaa)DE-He213 Gliclazide (dpeaa)DE-He213 Emergency Department Physician (dpeaa)DE-He213 Aung, Myat Moe Thwe aut Kamauzaman, Tuan Hairulnizam Tuan aut Rahman, Ab Fatah Ab aut Enthalten in Drugs - real world outcomes New York, NY [u.a.] : SpringerOpen, 2014 2(2015), 4 vom: 23. Okt., Seite 387-395 (DE-627)815914024 (DE-600)2806600-5 2198-9788 nnns volume:2 year:2015 number:4 day:23 month:10 pages:387-395 https://dx.doi.org/10.1007/s40801-015-0045-2 kostenfrei Volltext GBV_USEFLAG_A SYSFLAG_A GBV_SPRINGER SSG-OLC-PHA GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_70 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_2009 GBV_ILN_2014 GBV_ILN_2111 GBV_ILN_2129 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4046 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 2 2015 4 23 10 387-395
allfieldsSound	10.1007/s40801-015-0045-2 doi (DE-627)SPR03781365X (SPR)s40801-015-0045-2-e DE-627 ger DE-627 rakwb eng Jatau, Abubakar Ibrahim verfasserin aut Prevalence of Drug-Related Emergency Department Visits at a Teaching Hospital in Malaysia 2015 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier © The Author(s) 2015 Background Data on the prevalence of adverse drug event (ADE)-related emergency department (ED) visits in developing countries are limited. Malaysia is located in South-East Asia, and, to our knowledge, no information exists on ADE-related ED visits. Objective The objective of this study was to determine the prevalence, preventability, severity, and outcome of drug-related ED visits. Methodology A cross-sectional study was conducted in consenting patients who visited the ED of Hospital Universiti Sains Malaysia over a 6-week period. The ED physician on duty determined whether or not the visit was drug related according to set criteria. Other relevant information was extracted from the patient’s medical folder by a clinical pharmacist. Results Of the 434 consenting patients, 133 (30.6 %; 95 % confidence interval [CI] 26–35 %) visits were determined to be ADE related; 55.5 % were considered preventable, 11.3 % possibly preventable, and 33.1 % not preventable. Severity was classed as mild in 1.5 %, moderate in 67.7 %, and severe in 30.8 %. The most common ADEs reported were drug therapeutic failure (55.6 %) and adverse drug reactions (32.3 %). The most frequently implicated drugs were antidiabetics (n = 31; 23.3 %), antihypertensives (n = 28; 21.1 %), antibiotics (n = 13; 9.8 %), and anti-asthmatics (n = 11; 8.3 %). A total of 93 patients (69.9 %) were admitted to the ED for observation, 25 (18.8 %) were discharged immediately after consultation, and 15 (11.3 %) were admitted to the ward through the ED. Conclusion The prevalence of ADE-related ED visits was high; more than one-half of the events were considered preventable and one-third was classed as severe. As such, preventive measures will minimize future occurrences and increase patient safety. Emergency Department (dpeaa)DE-He213 Emergency Department Visit (dpeaa)DE-He213 Adverse Drug Event (dpeaa)DE-He213 Gliclazide (dpeaa)DE-He213 Emergency Department Physician (dpeaa)DE-He213 Aung, Myat Moe Thwe aut Kamauzaman, Tuan Hairulnizam Tuan aut Rahman, Ab Fatah Ab aut Enthalten in Drugs - real world outcomes New York, NY [u.a.] : SpringerOpen, 2014 2(2015), 4 vom: 23. Okt., Seite 387-395 (DE-627)815914024 (DE-600)2806600-5 2198-9788 nnns volume:2 year:2015 number:4 day:23 month:10 pages:387-395 https://dx.doi.org/10.1007/s40801-015-0045-2 kostenfrei Volltext GBV_USEFLAG_A SYSFLAG_A GBV_SPRINGER SSG-OLC-PHA GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_70 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_2009 GBV_ILN_2014 GBV_ILN_2111 GBV_ILN_2129 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4046 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 2 2015 4 23 10 387-395
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authorswithroles_txt_mv	Jatau, Abubakar Ibrahim @@aut@@ Aung, Myat Moe Thwe @@aut@@ Kamauzaman, Tuan Hairulnizam Tuan @@aut@@ Rahman, Ab Fatah Ab @@aut@@
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Malaysia is located in South-East Asia, and, to our knowledge, no information exists on ADE-related ED visits. Objective The objective of this study was to determine the prevalence, preventability, severity, and outcome of drug-related ED visits. Methodology A cross-sectional study was conducted in consenting patients who visited the ED of Hospital Universiti Sains Malaysia over a 6-week period. The ED physician on duty determined whether or not the visit was drug related according to set criteria. Other relevant information was extracted from the patient’s medical folder by a clinical pharmacist. Results Of the 434 consenting patients, 133 (30.6 %; 95 % confidence interval [CI] 26–35 %) visits were determined to be ADE related; 55.5 % were considered preventable, 11.3 % possibly preventable, and 33.1 % not preventable. Severity was classed as mild in 1.5 %, moderate in 67.7 %, and severe in 30.8 %. The most common ADEs reported were drug therapeutic failure (55.6 %) and adverse drug reactions (32.3 %). The most frequently implicated drugs were antidiabetics (n = 31; 23.3 %), antihypertensives (n = 28; 21.1 %), antibiotics (n = 13; 9.8 %), and anti-asthmatics (n = 11; 8.3 %). A total of 93 patients (69.9 %) were admitted to the ED for observation, 25 (18.8 %) were discharged immediately after consultation, and 15 (11.3 %) were admitted to the ward through the ED. Conclusion The prevalence of ADE-related ED visits was high; more than one-half of the events were considered preventable and one-third was classed as severe. 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author	Jatau, Abubakar Ibrahim
spellingShingle	Jatau, Abubakar Ibrahim misc Emergency Department misc Emergency Department Visit misc Adverse Drug Event misc Gliclazide misc Emergency Department Physician Prevalence of Drug-Related Emergency Department Visits at a Teaching Hospital in Malaysia
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topic_title	Prevalence of Drug-Related Emergency Department Visits at a Teaching Hospital in Malaysia Emergency Department (dpeaa)DE-He213 Emergency Department Visit (dpeaa)DE-He213 Adverse Drug Event (dpeaa)DE-He213 Gliclazide (dpeaa)DE-He213 Emergency Department Physician (dpeaa)DE-He213
topic	misc Emergency Department misc Emergency Department Visit misc Adverse Drug Event misc Gliclazide misc Emergency Department Physician
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title	Prevalence of Drug-Related Emergency Department Visits at a Teaching Hospital in Malaysia
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title_full	Prevalence of Drug-Related Emergency Department Visits at a Teaching Hospital in Malaysia
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author_browse	Jatau, Abubakar Ibrahim Aung, Myat Moe Thwe Kamauzaman, Tuan Hairulnizam Tuan Rahman, Ab Fatah Ab
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doi_str_mv	10.1007/s40801-015-0045-2
title_sort	prevalence of drug-related emergency department visits at a teaching hospital in malaysia
title_auth	Prevalence of Drug-Related Emergency Department Visits at a Teaching Hospital in Malaysia
abstract	Background Data on the prevalence of adverse drug event (ADE)-related emergency department (ED) visits in developing countries are limited. Malaysia is located in South-East Asia, and, to our knowledge, no information exists on ADE-related ED visits. Objective The objective of this study was to determine the prevalence, preventability, severity, and outcome of drug-related ED visits. Methodology A cross-sectional study was conducted in consenting patients who visited the ED of Hospital Universiti Sains Malaysia over a 6-week period. The ED physician on duty determined whether or not the visit was drug related according to set criteria. Other relevant information was extracted from the patient’s medical folder by a clinical pharmacist. Results Of the 434 consenting patients, 133 (30.6 %; 95 % confidence interval [CI] 26–35 %) visits were determined to be ADE related; 55.5 % were considered preventable, 11.3 % possibly preventable, and 33.1 % not preventable. Severity was classed as mild in 1.5 %, moderate in 67.7 %, and severe in 30.8 %. The most common ADEs reported were drug therapeutic failure (55.6 %) and adverse drug reactions (32.3 %). The most frequently implicated drugs were antidiabetics (n = 31; 23.3 %), antihypertensives (n = 28; 21.1 %), antibiotics (n = 13; 9.8 %), and anti-asthmatics (n = 11; 8.3 %). A total of 93 patients (69.9 %) were admitted to the ED for observation, 25 (18.8 %) were discharged immediately after consultation, and 15 (11.3 %) were admitted to the ward through the ED. Conclusion The prevalence of ADE-related ED visits was high; more than one-half of the events were considered preventable and one-third was classed as severe. As such, preventive measures will minimize future occurrences and increase patient safety. © The Author(s) 2015
abstractGer	Background Data on the prevalence of adverse drug event (ADE)-related emergency department (ED) visits in developing countries are limited. Malaysia is located in South-East Asia, and, to our knowledge, no information exists on ADE-related ED visits. Objective The objective of this study was to determine the prevalence, preventability, severity, and outcome of drug-related ED visits. Methodology A cross-sectional study was conducted in consenting patients who visited the ED of Hospital Universiti Sains Malaysia over a 6-week period. The ED physician on duty determined whether or not the visit was drug related according to set criteria. Other relevant information was extracted from the patient’s medical folder by a clinical pharmacist. Results Of the 434 consenting patients, 133 (30.6 %; 95 % confidence interval [CI] 26–35 %) visits were determined to be ADE related; 55.5 % were considered preventable, 11.3 % possibly preventable, and 33.1 % not preventable. Severity was classed as mild in 1.5 %, moderate in 67.7 %, and severe in 30.8 %. The most common ADEs reported were drug therapeutic failure (55.6 %) and adverse drug reactions (32.3 %). The most frequently implicated drugs were antidiabetics (n = 31; 23.3 %), antihypertensives (n = 28; 21.1 %), antibiotics (n = 13; 9.8 %), and anti-asthmatics (n = 11; 8.3 %). A total of 93 patients (69.9 %) were admitted to the ED for observation, 25 (18.8 %) were discharged immediately after consultation, and 15 (11.3 %) were admitted to the ward through the ED. Conclusion The prevalence of ADE-related ED visits was high; more than one-half of the events were considered preventable and one-third was classed as severe. As such, preventive measures will minimize future occurrences and increase patient safety. © The Author(s) 2015
abstract_unstemmed	Background Data on the prevalence of adverse drug event (ADE)-related emergency department (ED) visits in developing countries are limited. Malaysia is located in South-East Asia, and, to our knowledge, no information exists on ADE-related ED visits. Objective The objective of this study was to determine the prevalence, preventability, severity, and outcome of drug-related ED visits. Methodology A cross-sectional study was conducted in consenting patients who visited the ED of Hospital Universiti Sains Malaysia over a 6-week period. The ED physician on duty determined whether or not the visit was drug related according to set criteria. Other relevant information was extracted from the patient’s medical folder by a clinical pharmacist. Results Of the 434 consenting patients, 133 (30.6 %; 95 % confidence interval [CI] 26–35 %) visits were determined to be ADE related; 55.5 % were considered preventable, 11.3 % possibly preventable, and 33.1 % not preventable. Severity was classed as mild in 1.5 %, moderate in 67.7 %, and severe in 30.8 %. The most common ADEs reported were drug therapeutic failure (55.6 %) and adverse drug reactions (32.3 %). The most frequently implicated drugs were antidiabetics (n = 31; 23.3 %), antihypertensives (n = 28; 21.1 %), antibiotics (n = 13; 9.8 %), and anti-asthmatics (n = 11; 8.3 %). A total of 93 patients (69.9 %) were admitted to the ED for observation, 25 (18.8 %) were discharged immediately after consultation, and 15 (11.3 %) were admitted to the ward through the ED. Conclusion The prevalence of ADE-related ED visits was high; more than one-half of the events were considered preventable and one-third was classed as severe. As such, preventive measures will minimize future occurrences and increase patient safety. © The Author(s) 2015
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title_short	Prevalence of Drug-Related Emergency Department Visits at a Teaching Hospital in Malaysia
url	https://dx.doi.org/10.1007/s40801-015-0045-2
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author2	Aung, Myat Moe Thwe Kamauzaman, Tuan Hairulnizam Tuan Rahman, Ab Fatah Ab
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Malaysia is located in South-East Asia, and, to our knowledge, no information exists on ADE-related ED visits. Objective The objective of this study was to determine the prevalence, preventability, severity, and outcome of drug-related ED visits. Methodology A cross-sectional study was conducted in consenting patients who visited the ED of Hospital Universiti Sains Malaysia over a 6-week period. The ED physician on duty determined whether or not the visit was drug related according to set criteria. Other relevant information was extracted from the patient’s medical folder by a clinical pharmacist. Results Of the 434 consenting patients, 133 (30.6 %; 95 % confidence interval [CI] 26–35 %) visits were determined to be ADE related; 55.5 % were considered preventable, 11.3 % possibly preventable, and 33.1 % not preventable. Severity was classed as mild in 1.5 %, moderate in 67.7 %, and severe in 30.8 %. The most common ADEs reported were drug therapeutic failure (55.6 %) and adverse drug reactions (32.3 %). The most frequently implicated drugs were antidiabetics (n = 31; 23.3 %), antihypertensives (n = 28; 21.1 %), antibiotics (n = 13; 9.8 %), and anti-asthmatics (n = 11; 8.3 %). A total of 93 patients (69.9 %) were admitted to the ED for observation, 25 (18.8 %) were discharged immediately after consultation, and 15 (11.3 %) were admitted to the ward through the ED. Conclusion The prevalence of ADE-related ED visits was high; more than one-half of the events were considered preventable and one-third was classed as severe. 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Prevalence of Drug-Related Emergency Department Visits at a Teaching Hospital in Malaysia

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