Pod-Like Supramicelles with Multicompartment Hydrophobic Cores Prepared by Self-Assembly of Modified Chitosan

Abstract In this paper, pod-like supramicelles with multicompartment hydrophobic cores were prepared by self-assembly of amphiphilic N-phthaloylchitosan-g-poly(N-vinylcaprolactam) (PHCS-g-PNVCL) in aqueous medium. The employed biocompatible amphiphilic polymer was synthesized by grafting the carboxy...
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Autor*in:	Wang, Yiming [verfasserIn] Wang, Jie Wang, Tongshuai Xu, Yisheng Shi, Lei Wu, Yongtao Li, Li Guo, Xuhong

Format:	E-Artikel
Sprache:	Englisch

Erschienen:	2015

Schlagwörter:	Chitosan Graft copolymers Amphiphiles Self-assembly Multicompartment supramicelles

Anmerkung:	© The Author(s) 2015

Übergeordnetes Werk:	Enthalten in: Nano-Micro letters - Berlin : Springer, 2009, 8(2015), 2 vom: 27. Okt., Seite 151-156
Übergeordnetes Werk:	volume:8 ; year:2015 ; number:2 ; day:27 ; month:10 ; pages:151-156

Links:	Volltext

DOI / URN:	10.1007/s40820-015-0070-4

Katalog-ID:	SPR03787733X

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520			\|a Abstract In this paper, pod-like supramicelles with multicompartment hydrophobic cores were prepared by self-assembly of amphiphilic N-phthaloylchitosan-g-poly(N-vinylcaprolactam) (PHCS-g-PNVCL) in aqueous medium. The employed biocompatible amphiphilic polymer was synthesized by grafting the carboxyl terminated poly(N-vinylcaprolactam) (PNVCL-COOH) chains onto N-phthaloylchitosan (PHCS) backbone. 1H NMR and FTIR results confirmed the molecular structure of the copolymers. The morphology of the supramicelles assembled by PHCS-g-PNVCL was revealed by means of TEM and polarized light microscope. In solution, the supramicelles were very stable as monitored by DLS and zeta potential measurements. Temperature and pH presented significant influences on the size and size distribution of the supramicelles. These supramicelles with multicompartment hydrophobic cores should be ideal biomimetic systems with promising applications in drug delivery.
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Indexfelder

author_variant	y w yw j w jw t w tw y x yx l s ls y w yw l l ll x g xg
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allfields	10.1007/s40820-015-0070-4 doi (DE-627)SPR03787733X (SPR)s40820-015-0070-4-e DE-627 ger DE-627 rakwb eng Wang, Yiming verfasserin aut Pod-Like Supramicelles with Multicompartment Hydrophobic Cores Prepared by Self-Assembly of Modified Chitosan 2015 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier © The Author(s) 2015 Abstract In this paper, pod-like supramicelles with multicompartment hydrophobic cores were prepared by self-assembly of amphiphilic N-phthaloylchitosan-g-poly(N-vinylcaprolactam) (PHCS-g-PNVCL) in aqueous medium. The employed biocompatible amphiphilic polymer was synthesized by grafting the carboxyl terminated poly(N-vinylcaprolactam) (PNVCL-COOH) chains onto N-phthaloylchitosan (PHCS) backbone. 1H NMR and FTIR results confirmed the molecular structure of the copolymers. The morphology of the supramicelles assembled by PHCS-g-PNVCL was revealed by means of TEM and polarized light microscope. In solution, the supramicelles were very stable as monitored by DLS and zeta potential measurements. Temperature and pH presented significant influences on the size and size distribution of the supramicelles. These supramicelles with multicompartment hydrophobic cores should be ideal biomimetic systems with promising applications in drug delivery. Chitosan (dpeaa)DE-He213 Graft copolymers (dpeaa)DE-He213 Amphiphiles (dpeaa)DE-He213 Self-assembly (dpeaa)DE-He213 Multicompartment supramicelles (dpeaa)DE-He213 Wang, Jie aut Wang, Tongshuai aut Xu, Yisheng aut Shi, Lei aut Wu, Yongtao aut Li, Li aut Guo, Xuhong aut Enthalten in Nano-Micro letters Berlin : Springer, 2009 8(2015), 2 vom: 27. Okt., Seite 151-156 (DE-627)680319581 (DE-600)2642093-4 2150-5551 nnns volume:8 year:2015 number:2 day:27 month:10 pages:151-156 https://dx.doi.org/10.1007/s40820-015-0070-4 kostenfrei Volltext GBV_USEFLAG_A SYSFLAG_A GBV_SPRINGER SSG-OLC-PHA GBV_ILN_11 GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_39 GBV_ILN_40 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_70 GBV_ILN_73 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_206 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_370 GBV_ILN_602 GBV_ILN_2005 GBV_ILN_2009 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2027 GBV_ILN_2055 GBV_ILN_2111 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4335 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 8 2015 2 27 10 151-156
spelling	10.1007/s40820-015-0070-4 doi (DE-627)SPR03787733X (SPR)s40820-015-0070-4-e DE-627 ger DE-627 rakwb eng Wang, Yiming verfasserin aut Pod-Like Supramicelles with Multicompartment Hydrophobic Cores Prepared by Self-Assembly of Modified Chitosan 2015 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier © The Author(s) 2015 Abstract In this paper, pod-like supramicelles with multicompartment hydrophobic cores were prepared by self-assembly of amphiphilic N-phthaloylchitosan-g-poly(N-vinylcaprolactam) (PHCS-g-PNVCL) in aqueous medium. The employed biocompatible amphiphilic polymer was synthesized by grafting the carboxyl terminated poly(N-vinylcaprolactam) (PNVCL-COOH) chains onto N-phthaloylchitosan (PHCS) backbone. 1H NMR and FTIR results confirmed the molecular structure of the copolymers. The morphology of the supramicelles assembled by PHCS-g-PNVCL was revealed by means of TEM and polarized light microscope. In solution, the supramicelles were very stable as monitored by DLS and zeta potential measurements. Temperature and pH presented significant influences on the size and size distribution of the supramicelles. These supramicelles with multicompartment hydrophobic cores should be ideal biomimetic systems with promising applications in drug delivery. Chitosan (dpeaa)DE-He213 Graft copolymers (dpeaa)DE-He213 Amphiphiles (dpeaa)DE-He213 Self-assembly (dpeaa)DE-He213 Multicompartment supramicelles (dpeaa)DE-He213 Wang, Jie aut Wang, Tongshuai aut Xu, Yisheng aut Shi, Lei aut Wu, Yongtao aut Li, Li aut Guo, Xuhong aut Enthalten in Nano-Micro letters Berlin : Springer, 2009 8(2015), 2 vom: 27. Okt., Seite 151-156 (DE-627)680319581 (DE-600)2642093-4 2150-5551 nnns volume:8 year:2015 number:2 day:27 month:10 pages:151-156 https://dx.doi.org/10.1007/s40820-015-0070-4 kostenfrei Volltext GBV_USEFLAG_A SYSFLAG_A GBV_SPRINGER SSG-OLC-PHA GBV_ILN_11 GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_39 GBV_ILN_40 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_70 GBV_ILN_73 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_206 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_370 GBV_ILN_602 GBV_ILN_2005 GBV_ILN_2009 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2027 GBV_ILN_2055 GBV_ILN_2111 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4335 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 8 2015 2 27 10 151-156
allfields_unstemmed	10.1007/s40820-015-0070-4 doi (DE-627)SPR03787733X (SPR)s40820-015-0070-4-e DE-627 ger DE-627 rakwb eng Wang, Yiming verfasserin aut Pod-Like Supramicelles with Multicompartment Hydrophobic Cores Prepared by Self-Assembly of Modified Chitosan 2015 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier © The Author(s) 2015 Abstract In this paper, pod-like supramicelles with multicompartment hydrophobic cores were prepared by self-assembly of amphiphilic N-phthaloylchitosan-g-poly(N-vinylcaprolactam) (PHCS-g-PNVCL) in aqueous medium. The employed biocompatible amphiphilic polymer was synthesized by grafting the carboxyl terminated poly(N-vinylcaprolactam) (PNVCL-COOH) chains onto N-phthaloylchitosan (PHCS) backbone. 1H NMR and FTIR results confirmed the molecular structure of the copolymers. The morphology of the supramicelles assembled by PHCS-g-PNVCL was revealed by means of TEM and polarized light microscope. In solution, the supramicelles were very stable as monitored by DLS and zeta potential measurements. Temperature and pH presented significant influences on the size and size distribution of the supramicelles. These supramicelles with multicompartment hydrophobic cores should be ideal biomimetic systems with promising applications in drug delivery. Chitosan (dpeaa)DE-He213 Graft copolymers (dpeaa)DE-He213 Amphiphiles (dpeaa)DE-He213 Self-assembly (dpeaa)DE-He213 Multicompartment supramicelles (dpeaa)DE-He213 Wang, Jie aut Wang, Tongshuai aut Xu, Yisheng aut Shi, Lei aut Wu, Yongtao aut Li, Li aut Guo, Xuhong aut Enthalten in Nano-Micro letters Berlin : Springer, 2009 8(2015), 2 vom: 27. Okt., Seite 151-156 (DE-627)680319581 (DE-600)2642093-4 2150-5551 nnns volume:8 year:2015 number:2 day:27 month:10 pages:151-156 https://dx.doi.org/10.1007/s40820-015-0070-4 kostenfrei Volltext GBV_USEFLAG_A SYSFLAG_A GBV_SPRINGER SSG-OLC-PHA GBV_ILN_11 GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_39 GBV_ILN_40 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_70 GBV_ILN_73 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_206 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_370 GBV_ILN_602 GBV_ILN_2005 GBV_ILN_2009 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2027 GBV_ILN_2055 GBV_ILN_2111 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4335 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 8 2015 2 27 10 151-156
allfieldsGer	10.1007/s40820-015-0070-4 doi (DE-627)SPR03787733X (SPR)s40820-015-0070-4-e DE-627 ger DE-627 rakwb eng Wang, Yiming verfasserin aut Pod-Like Supramicelles with Multicompartment Hydrophobic Cores Prepared by Self-Assembly of Modified Chitosan 2015 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier © The Author(s) 2015 Abstract In this paper, pod-like supramicelles with multicompartment hydrophobic cores were prepared by self-assembly of amphiphilic N-phthaloylchitosan-g-poly(N-vinylcaprolactam) (PHCS-g-PNVCL) in aqueous medium. The employed biocompatible amphiphilic polymer was synthesized by grafting the carboxyl terminated poly(N-vinylcaprolactam) (PNVCL-COOH) chains onto N-phthaloylchitosan (PHCS) backbone. 1H NMR and FTIR results confirmed the molecular structure of the copolymers. The morphology of the supramicelles assembled by PHCS-g-PNVCL was revealed by means of TEM and polarized light microscope. In solution, the supramicelles were very stable as monitored by DLS and zeta potential measurements. Temperature and pH presented significant influences on the size and size distribution of the supramicelles. These supramicelles with multicompartment hydrophobic cores should be ideal biomimetic systems with promising applications in drug delivery. Chitosan (dpeaa)DE-He213 Graft copolymers (dpeaa)DE-He213 Amphiphiles (dpeaa)DE-He213 Self-assembly (dpeaa)DE-He213 Multicompartment supramicelles (dpeaa)DE-He213 Wang, Jie aut Wang, Tongshuai aut Xu, Yisheng aut Shi, Lei aut Wu, Yongtao aut Li, Li aut Guo, Xuhong aut Enthalten in Nano-Micro letters Berlin : Springer, 2009 8(2015), 2 vom: 27. Okt., Seite 151-156 (DE-627)680319581 (DE-600)2642093-4 2150-5551 nnns volume:8 year:2015 number:2 day:27 month:10 pages:151-156 https://dx.doi.org/10.1007/s40820-015-0070-4 kostenfrei Volltext GBV_USEFLAG_A SYSFLAG_A GBV_SPRINGER SSG-OLC-PHA GBV_ILN_11 GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_39 GBV_ILN_40 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_70 GBV_ILN_73 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_206 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_370 GBV_ILN_602 GBV_ILN_2005 GBV_ILN_2009 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2027 GBV_ILN_2055 GBV_ILN_2111 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4335 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 8 2015 2 27 10 151-156
allfieldsSound	10.1007/s40820-015-0070-4 doi (DE-627)SPR03787733X (SPR)s40820-015-0070-4-e DE-627 ger DE-627 rakwb eng Wang, Yiming verfasserin aut Pod-Like Supramicelles with Multicompartment Hydrophobic Cores Prepared by Self-Assembly of Modified Chitosan 2015 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier © The Author(s) 2015 Abstract In this paper, pod-like supramicelles with multicompartment hydrophobic cores were prepared by self-assembly of amphiphilic N-phthaloylchitosan-g-poly(N-vinylcaprolactam) (PHCS-g-PNVCL) in aqueous medium. The employed biocompatible amphiphilic polymer was synthesized by grafting the carboxyl terminated poly(N-vinylcaprolactam) (PNVCL-COOH) chains onto N-phthaloylchitosan (PHCS) backbone. 1H NMR and FTIR results confirmed the molecular structure of the copolymers. The morphology of the supramicelles assembled by PHCS-g-PNVCL was revealed by means of TEM and polarized light microscope. In solution, the supramicelles were very stable as monitored by DLS and zeta potential measurements. Temperature and pH presented significant influences on the size and size distribution of the supramicelles. These supramicelles with multicompartment hydrophobic cores should be ideal biomimetic systems with promising applications in drug delivery. Chitosan (dpeaa)DE-He213 Graft copolymers (dpeaa)DE-He213 Amphiphiles (dpeaa)DE-He213 Self-assembly (dpeaa)DE-He213 Multicompartment supramicelles (dpeaa)DE-He213 Wang, Jie aut Wang, Tongshuai aut Xu, Yisheng aut Shi, Lei aut Wu, Yongtao aut Li, Li aut Guo, Xuhong aut Enthalten in Nano-Micro letters Berlin : Springer, 2009 8(2015), 2 vom: 27. Okt., Seite 151-156 (DE-627)680319581 (DE-600)2642093-4 2150-5551 nnns volume:8 year:2015 number:2 day:27 month:10 pages:151-156 https://dx.doi.org/10.1007/s40820-015-0070-4 kostenfrei Volltext GBV_USEFLAG_A SYSFLAG_A GBV_SPRINGER SSG-OLC-PHA GBV_ILN_11 GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_39 GBV_ILN_40 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_70 GBV_ILN_73 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_206 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_370 GBV_ILN_602 GBV_ILN_2005 GBV_ILN_2009 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2027 GBV_ILN_2055 GBV_ILN_2111 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4335 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 8 2015 2 27 10 151-156
language	English
source	Enthalten in Nano-Micro letters 8(2015), 2 vom: 27. Okt., Seite 151-156 volume:8 year:2015 number:2 day:27 month:10 pages:151-156
sourceStr	Enthalten in Nano-Micro letters 8(2015), 2 vom: 27. Okt., Seite 151-156 volume:8 year:2015 number:2 day:27 month:10 pages:151-156
format_phy_str_mv	Article
institution	findex.gbv.de
topic_facet	Chitosan Graft copolymers Amphiphiles Self-assembly Multicompartment supramicelles
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container_title	Nano-Micro letters
authorswithroles_txt_mv	Wang, Yiming @@aut@@ Wang, Jie @@aut@@ Wang, Tongshuai @@aut@@ Xu, Yisheng @@aut@@ Shi, Lei @@aut@@ Wu, Yongtao @@aut@@ Li, Li @@aut@@ Guo, Xuhong @@aut@@
publishDateDaySort_date	2015-10-27T00:00:00Z
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author	Wang, Yiming
spellingShingle	Wang, Yiming misc Chitosan misc Graft copolymers misc Amphiphiles misc Self-assembly misc Multicompartment supramicelles Pod-Like Supramicelles with Multicompartment Hydrophobic Cores Prepared by Self-Assembly of Modified Chitosan
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topic_title	Pod-Like Supramicelles with Multicompartment Hydrophobic Cores Prepared by Self-Assembly of Modified Chitosan Chitosan (dpeaa)DE-He213 Graft copolymers (dpeaa)DE-He213 Amphiphiles (dpeaa)DE-He213 Self-assembly (dpeaa)DE-He213 Multicompartment supramicelles (dpeaa)DE-He213
topic	misc Chitosan misc Graft copolymers misc Amphiphiles misc Self-assembly misc Multicompartment supramicelles
topic_unstemmed	misc Chitosan misc Graft copolymers misc Amphiphiles misc Self-assembly misc Multicompartment supramicelles
topic_browse	misc Chitosan misc Graft copolymers misc Amphiphiles misc Self-assembly misc Multicompartment supramicelles
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title	Pod-Like Supramicelles with Multicompartment Hydrophobic Cores Prepared by Self-Assembly of Modified Chitosan
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title_full	Pod-Like Supramicelles with Multicompartment Hydrophobic Cores Prepared by Self-Assembly of Modified Chitosan
author_sort	Wang, Yiming
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author_browse	Wang, Yiming Wang, Jie Wang, Tongshuai Xu, Yisheng Shi, Lei Wu, Yongtao Li, Li Guo, Xuhong
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doi_str_mv	10.1007/s40820-015-0070-4
title_sort	pod-like supramicelles with multicompartment hydrophobic cores prepared by self-assembly of modified chitosan
title_auth	Pod-Like Supramicelles with Multicompartment Hydrophobic Cores Prepared by Self-Assembly of Modified Chitosan
abstract	Abstract In this paper, pod-like supramicelles with multicompartment hydrophobic cores were prepared by self-assembly of amphiphilic N-phthaloylchitosan-g-poly(N-vinylcaprolactam) (PHCS-g-PNVCL) in aqueous medium. The employed biocompatible amphiphilic polymer was synthesized by grafting the carboxyl terminated poly(N-vinylcaprolactam) (PNVCL-COOH) chains onto N-phthaloylchitosan (PHCS) backbone. 1H NMR and FTIR results confirmed the molecular structure of the copolymers. The morphology of the supramicelles assembled by PHCS-g-PNVCL was revealed by means of TEM and polarized light microscope. In solution, the supramicelles were very stable as monitored by DLS and zeta potential measurements. Temperature and pH presented significant influences on the size and size distribution of the supramicelles. These supramicelles with multicompartment hydrophobic cores should be ideal biomimetic systems with promising applications in drug delivery. © The Author(s) 2015
abstractGer	Abstract In this paper, pod-like supramicelles with multicompartment hydrophobic cores were prepared by self-assembly of amphiphilic N-phthaloylchitosan-g-poly(N-vinylcaprolactam) (PHCS-g-PNVCL) in aqueous medium. The employed biocompatible amphiphilic polymer was synthesized by grafting the carboxyl terminated poly(N-vinylcaprolactam) (PNVCL-COOH) chains onto N-phthaloylchitosan (PHCS) backbone. 1H NMR and FTIR results confirmed the molecular structure of the copolymers. The morphology of the supramicelles assembled by PHCS-g-PNVCL was revealed by means of TEM and polarized light microscope. In solution, the supramicelles were very stable as monitored by DLS and zeta potential measurements. Temperature and pH presented significant influences on the size and size distribution of the supramicelles. These supramicelles with multicompartment hydrophobic cores should be ideal biomimetic systems with promising applications in drug delivery. © The Author(s) 2015
abstract_unstemmed	Abstract In this paper, pod-like supramicelles with multicompartment hydrophobic cores were prepared by self-assembly of amphiphilic N-phthaloylchitosan-g-poly(N-vinylcaprolactam) (PHCS-g-PNVCL) in aqueous medium. The employed biocompatible amphiphilic polymer was synthesized by grafting the carboxyl terminated poly(N-vinylcaprolactam) (PNVCL-COOH) chains onto N-phthaloylchitosan (PHCS) backbone. 1H NMR and FTIR results confirmed the molecular structure of the copolymers. The morphology of the supramicelles assembled by PHCS-g-PNVCL was revealed by means of TEM and polarized light microscope. In solution, the supramicelles were very stable as monitored by DLS and zeta potential measurements. Temperature and pH presented significant influences on the size and size distribution of the supramicelles. These supramicelles with multicompartment hydrophobic cores should be ideal biomimetic systems with promising applications in drug delivery. © The Author(s) 2015
collection_details	GBV_USEFLAG_A SYSFLAG_A GBV_SPRINGER SSG-OLC-PHA GBV_ILN_11 GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_39 GBV_ILN_40 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_70 GBV_ILN_73 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_206 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_370 GBV_ILN_602 GBV_ILN_2005 GBV_ILN_2009 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2027 GBV_ILN_2055 GBV_ILN_2111 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4335 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700
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title_short	Pod-Like Supramicelles with Multicompartment Hydrophobic Cores Prepared by Self-Assembly of Modified Chitosan
url	https://dx.doi.org/10.1007/s40820-015-0070-4
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author2	Wang, Jie Wang, Tongshuai Xu, Yisheng Shi, Lei Wu, Yongtao Li, Li Guo, Xuhong
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up_date	2024-07-03T14:53:12.543Z
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Pod-Like Supramicelles with Multicompartment Hydrophobic Cores Prepared by Self-Assembly of Modified Chitosan

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