Changes in the ankle-brachial blood pressure index among hemodialysis patients

Background The ankle-brachial blood pressure index (ABI) is an independent predictor of mortality in hemodialysis patients. In the present study, we investigated the factors that predict changes in the ABI in hemodialysis patients. Methods A total of 61 consecutive patients receiving maintenance hem...
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Autor*in:	Abe, Takayuki [verfasserIn] Otsubo, Shigeru Kimata, Naoki Okajima, Tomoki Otani, Yumi Murakami, Jun Kaneko, Iwakazu Miwa, Naoko Mineshima, Michio Tsuchiya, Ken Nitta, Kosaku Akiba, Takashi

Format:	E-Artikel
Sprache:	Englisch

Erschienen:	2016

Schlagwörter:	Ankle-brachial index Hemodialysis Peripheral artery disease

Anmerkung:	© The Author(s) 2016

Übergeordnetes Werk:	Enthalten in: Renal replacement therapy - [London] : BioMed Central, 2015, 2(2016), 1 vom: 29. Aug.
Übergeordnetes Werk:	volume:2 ; year:2016 ; number:1 ; day:29 ; month:08

Links:	Volltext

DOI / URN:	10.1186/s41100-016-0053-z

Katalog-ID:	SPR03825011X

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520			\|a Background The ankle-brachial blood pressure index (ABI) is an independent predictor of mortality in hemodialysis patients. In the present study, we investigated the factors that predict changes in the ABI in hemodialysis patients. Methods A total of 61 consecutive patients receiving maintenance hemodialysis who successfully underwent ABI examinations in 2005 and 2011 were enrolled in this study. The change in the ABI (2011 measurement versus 2005 measurement) was estimated. We set the baseline at 2011 and investigated the patient outcomes. Furthermore, we compared the change in the ABI and several clinical factors observed in 2005. Results The mean follow-up period was 3.1 ± 0.7 years. In the univariate Cox proportional hazard analysis, predictive variables for mortality included ABI (0.43 [0.25–0.64]; [per 0.1 increase]) and the change in the ABI (0.62 [0.49–0.79]; [per 0.1 increase]). Patient age was negatively correlated and the serum creatinine level was positively correlated with the change in the ABI (P = 0.030 and 0.022, respectively). Conclusions We confirmed that not only the value of the ABI itself but also the change in the ABI was a risk factor for mortality among hemodialysis patients. The change in the ABI was negatively correlated with age and was positively correlated with the serum creatinine level. Careful observation of the ABI is needed for old patients and patients with a low serum creatinine level.
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allfields	10.1186/s41100-016-0053-z doi (DE-627)SPR03825011X (SPR)s41100-016-0053-z-e DE-627 ger DE-627 rakwb eng Abe, Takayuki verfasserin aut Changes in the ankle-brachial blood pressure index among hemodialysis patients 2016 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier © The Author(s) 2016 Background The ankle-brachial blood pressure index (ABI) is an independent predictor of mortality in hemodialysis patients. In the present study, we investigated the factors that predict changes in the ABI in hemodialysis patients. Methods A total of 61 consecutive patients receiving maintenance hemodialysis who successfully underwent ABI examinations in 2005 and 2011 were enrolled in this study. The change in the ABI (2011 measurement versus 2005 measurement) was estimated. We set the baseline at 2011 and investigated the patient outcomes. Furthermore, we compared the change in the ABI and several clinical factors observed in 2005. Results The mean follow-up period was 3.1 ± 0.7 years. In the univariate Cox proportional hazard analysis, predictive variables for mortality included ABI (0.43 [0.25–0.64]; [per 0.1 increase]) and the change in the ABI (0.62 [0.49–0.79]; [per 0.1 increase]). Patient age was negatively correlated and the serum creatinine level was positively correlated with the change in the ABI (P = 0.030 and 0.022, respectively). Conclusions We confirmed that not only the value of the ABI itself but also the change in the ABI was a risk factor for mortality among hemodialysis patients. The change in the ABI was negatively correlated with age and was positively correlated with the serum creatinine level. Careful observation of the ABI is needed for old patients and patients with a low serum creatinine level. Ankle-brachial index (dpeaa)DE-He213 Hemodialysis (dpeaa)DE-He213 Peripheral artery disease (dpeaa)DE-He213 Otsubo, Shigeru aut Kimata, Naoki aut Okajima, Tomoki aut Otani, Yumi aut Murakami, Jun aut Kaneko, Iwakazu aut Miwa, Naoko aut Mineshima, Michio aut Tsuchiya, Ken aut Nitta, Kosaku aut Akiba, Takashi aut Enthalten in Renal replacement therapy [London] : BioMed Central, 2015 2(2016), 1 vom: 29. Aug. (DE-627)866576487 (DE-600)2866852-2 2059-1381 nnns volume:2 year:2016 number:1 day:29 month:08 https://dx.doi.org/10.1186/s41100-016-0053-z kostenfrei Volltext GBV_USEFLAG_A SYSFLAG_A GBV_SPRINGER SSG-OLC-PHA GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_2014 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 2 2016 1 29 08
spelling	10.1186/s41100-016-0053-z doi (DE-627)SPR03825011X (SPR)s41100-016-0053-z-e DE-627 ger DE-627 rakwb eng Abe, Takayuki verfasserin aut Changes in the ankle-brachial blood pressure index among hemodialysis patients 2016 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier © The Author(s) 2016 Background The ankle-brachial blood pressure index (ABI) is an independent predictor of mortality in hemodialysis patients. In the present study, we investigated the factors that predict changes in the ABI in hemodialysis patients. Methods A total of 61 consecutive patients receiving maintenance hemodialysis who successfully underwent ABI examinations in 2005 and 2011 were enrolled in this study. The change in the ABI (2011 measurement versus 2005 measurement) was estimated. We set the baseline at 2011 and investigated the patient outcomes. Furthermore, we compared the change in the ABI and several clinical factors observed in 2005. Results The mean follow-up period was 3.1 ± 0.7 years. In the univariate Cox proportional hazard analysis, predictive variables for mortality included ABI (0.43 [0.25–0.64]; [per 0.1 increase]) and the change in the ABI (0.62 [0.49–0.79]; [per 0.1 increase]). Patient age was negatively correlated and the serum creatinine level was positively correlated with the change in the ABI (P = 0.030 and 0.022, respectively). Conclusions We confirmed that not only the value of the ABI itself but also the change in the ABI was a risk factor for mortality among hemodialysis patients. The change in the ABI was negatively correlated with age and was positively correlated with the serum creatinine level. Careful observation of the ABI is needed for old patients and patients with a low serum creatinine level. Ankle-brachial index (dpeaa)DE-He213 Hemodialysis (dpeaa)DE-He213 Peripheral artery disease (dpeaa)DE-He213 Otsubo, Shigeru aut Kimata, Naoki aut Okajima, Tomoki aut Otani, Yumi aut Murakami, Jun aut Kaneko, Iwakazu aut Miwa, Naoko aut Mineshima, Michio aut Tsuchiya, Ken aut Nitta, Kosaku aut Akiba, Takashi aut Enthalten in Renal replacement therapy [London] : BioMed Central, 2015 2(2016), 1 vom: 29. Aug. (DE-627)866576487 (DE-600)2866852-2 2059-1381 nnns volume:2 year:2016 number:1 day:29 month:08 https://dx.doi.org/10.1186/s41100-016-0053-z kostenfrei Volltext GBV_USEFLAG_A SYSFLAG_A GBV_SPRINGER SSG-OLC-PHA GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_2014 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 2 2016 1 29 08
allfields_unstemmed	10.1186/s41100-016-0053-z doi (DE-627)SPR03825011X (SPR)s41100-016-0053-z-e DE-627 ger DE-627 rakwb eng Abe, Takayuki verfasserin aut Changes in the ankle-brachial blood pressure index among hemodialysis patients 2016 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier © The Author(s) 2016 Background The ankle-brachial blood pressure index (ABI) is an independent predictor of mortality in hemodialysis patients. In the present study, we investigated the factors that predict changes in the ABI in hemodialysis patients. Methods A total of 61 consecutive patients receiving maintenance hemodialysis who successfully underwent ABI examinations in 2005 and 2011 were enrolled in this study. The change in the ABI (2011 measurement versus 2005 measurement) was estimated. We set the baseline at 2011 and investigated the patient outcomes. Furthermore, we compared the change in the ABI and several clinical factors observed in 2005. Results The mean follow-up period was 3.1 ± 0.7 years. In the univariate Cox proportional hazard analysis, predictive variables for mortality included ABI (0.43 [0.25–0.64]; [per 0.1 increase]) and the change in the ABI (0.62 [0.49–0.79]; [per 0.1 increase]). Patient age was negatively correlated and the serum creatinine level was positively correlated with the change in the ABI (P = 0.030 and 0.022, respectively). Conclusions We confirmed that not only the value of the ABI itself but also the change in the ABI was a risk factor for mortality among hemodialysis patients. The change in the ABI was negatively correlated with age and was positively correlated with the serum creatinine level. Careful observation of the ABI is needed for old patients and patients with a low serum creatinine level. Ankle-brachial index (dpeaa)DE-He213 Hemodialysis (dpeaa)DE-He213 Peripheral artery disease (dpeaa)DE-He213 Otsubo, Shigeru aut Kimata, Naoki aut Okajima, Tomoki aut Otani, Yumi aut Murakami, Jun aut Kaneko, Iwakazu aut Miwa, Naoko aut Mineshima, Michio aut Tsuchiya, Ken aut Nitta, Kosaku aut Akiba, Takashi aut Enthalten in Renal replacement therapy [London] : BioMed Central, 2015 2(2016), 1 vom: 29. Aug. (DE-627)866576487 (DE-600)2866852-2 2059-1381 nnns volume:2 year:2016 number:1 day:29 month:08 https://dx.doi.org/10.1186/s41100-016-0053-z kostenfrei Volltext GBV_USEFLAG_A SYSFLAG_A GBV_SPRINGER SSG-OLC-PHA GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_2014 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 2 2016 1 29 08
allfieldsGer	10.1186/s41100-016-0053-z doi (DE-627)SPR03825011X (SPR)s41100-016-0053-z-e DE-627 ger DE-627 rakwb eng Abe, Takayuki verfasserin aut Changes in the ankle-brachial blood pressure index among hemodialysis patients 2016 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier © The Author(s) 2016 Background The ankle-brachial blood pressure index (ABI) is an independent predictor of mortality in hemodialysis patients. In the present study, we investigated the factors that predict changes in the ABI in hemodialysis patients. Methods A total of 61 consecutive patients receiving maintenance hemodialysis who successfully underwent ABI examinations in 2005 and 2011 were enrolled in this study. The change in the ABI (2011 measurement versus 2005 measurement) was estimated. We set the baseline at 2011 and investigated the patient outcomes. Furthermore, we compared the change in the ABI and several clinical factors observed in 2005. Results The mean follow-up period was 3.1 ± 0.7 years. In the univariate Cox proportional hazard analysis, predictive variables for mortality included ABI (0.43 [0.25–0.64]; [per 0.1 increase]) and the change in the ABI (0.62 [0.49–0.79]; [per 0.1 increase]). Patient age was negatively correlated and the serum creatinine level was positively correlated with the change in the ABI (P = 0.030 and 0.022, respectively). Conclusions We confirmed that not only the value of the ABI itself but also the change in the ABI was a risk factor for mortality among hemodialysis patients. The change in the ABI was negatively correlated with age and was positively correlated with the serum creatinine level. Careful observation of the ABI is needed for old patients and patients with a low serum creatinine level. Ankle-brachial index (dpeaa)DE-He213 Hemodialysis (dpeaa)DE-He213 Peripheral artery disease (dpeaa)DE-He213 Otsubo, Shigeru aut Kimata, Naoki aut Okajima, Tomoki aut Otani, Yumi aut Murakami, Jun aut Kaneko, Iwakazu aut Miwa, Naoko aut Mineshima, Michio aut Tsuchiya, Ken aut Nitta, Kosaku aut Akiba, Takashi aut Enthalten in Renal replacement therapy [London] : BioMed Central, 2015 2(2016), 1 vom: 29. Aug. (DE-627)866576487 (DE-600)2866852-2 2059-1381 nnns volume:2 year:2016 number:1 day:29 month:08 https://dx.doi.org/10.1186/s41100-016-0053-z kostenfrei Volltext GBV_USEFLAG_A SYSFLAG_A GBV_SPRINGER SSG-OLC-PHA GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_2014 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 2 2016 1 29 08
allfieldsSound	10.1186/s41100-016-0053-z doi (DE-627)SPR03825011X (SPR)s41100-016-0053-z-e DE-627 ger DE-627 rakwb eng Abe, Takayuki verfasserin aut Changes in the ankle-brachial blood pressure index among hemodialysis patients 2016 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier © The Author(s) 2016 Background The ankle-brachial blood pressure index (ABI) is an independent predictor of mortality in hemodialysis patients. In the present study, we investigated the factors that predict changes in the ABI in hemodialysis patients. Methods A total of 61 consecutive patients receiving maintenance hemodialysis who successfully underwent ABI examinations in 2005 and 2011 were enrolled in this study. The change in the ABI (2011 measurement versus 2005 measurement) was estimated. We set the baseline at 2011 and investigated the patient outcomes. Furthermore, we compared the change in the ABI and several clinical factors observed in 2005. Results The mean follow-up period was 3.1 ± 0.7 years. In the univariate Cox proportional hazard analysis, predictive variables for mortality included ABI (0.43 [0.25–0.64]; [per 0.1 increase]) and the change in the ABI (0.62 [0.49–0.79]; [per 0.1 increase]). Patient age was negatively correlated and the serum creatinine level was positively correlated with the change in the ABI (P = 0.030 and 0.022, respectively). Conclusions We confirmed that not only the value of the ABI itself but also the change in the ABI was a risk factor for mortality among hemodialysis patients. The change in the ABI was negatively correlated with age and was positively correlated with the serum creatinine level. Careful observation of the ABI is needed for old patients and patients with a low serum creatinine level. Ankle-brachial index (dpeaa)DE-He213 Hemodialysis (dpeaa)DE-He213 Peripheral artery disease (dpeaa)DE-He213 Otsubo, Shigeru aut Kimata, Naoki aut Okajima, Tomoki aut Otani, Yumi aut Murakami, Jun aut Kaneko, Iwakazu aut Miwa, Naoko aut Mineshima, Michio aut Tsuchiya, Ken aut Nitta, Kosaku aut Akiba, Takashi aut Enthalten in Renal replacement therapy [London] : BioMed Central, 2015 2(2016), 1 vom: 29. Aug. (DE-627)866576487 (DE-600)2866852-2 2059-1381 nnns volume:2 year:2016 number:1 day:29 month:08 https://dx.doi.org/10.1186/s41100-016-0053-z kostenfrei Volltext GBV_USEFLAG_A SYSFLAG_A GBV_SPRINGER SSG-OLC-PHA GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_2014 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 2 2016 1 29 08
language	English
source	Enthalten in Renal replacement therapy 2(2016), 1 vom: 29. Aug. volume:2 year:2016 number:1 day:29 month:08
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In the present study, we investigated the factors that predict changes in the ABI in hemodialysis patients. Methods A total of 61 consecutive patients receiving maintenance hemodialysis who successfully underwent ABI examinations in 2005 and 2011 were enrolled in this study. The change in the ABI (2011 measurement versus 2005 measurement) was estimated. We set the baseline at 2011 and investigated the patient outcomes. Furthermore, we compared the change in the ABI and several clinical factors observed in 2005. Results The mean follow-up period was 3.1 ± 0.7 years. In the univariate Cox proportional hazard analysis, predictive variables for mortality included ABI (0.43 [0.25–0.64]; [per 0.1 increase]) and the change in the ABI (0.62 [0.49–0.79]; [per 0.1 increase]). Patient age was negatively correlated and the serum creatinine level was positively correlated with the change in the ABI (P = 0.030 and 0.022, respectively). Conclusions We confirmed that not only the value of the ABI itself but also the change in the ABI was a risk factor for mortality among hemodialysis patients. The change in the ABI was negatively correlated with age and was positively correlated with the serum creatinine level. 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author	Abe, Takayuki
spellingShingle	Abe, Takayuki misc Ankle-brachial index misc Hemodialysis misc Peripheral artery disease Changes in the ankle-brachial blood pressure index among hemodialysis patients
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topic_title	Changes in the ankle-brachial blood pressure index among hemodialysis patients Ankle-brachial index (dpeaa)DE-He213 Hemodialysis (dpeaa)DE-He213 Peripheral artery disease (dpeaa)DE-He213
topic	misc Ankle-brachial index misc Hemodialysis misc Peripheral artery disease
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title	Changes in the ankle-brachial blood pressure index among hemodialysis patients
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author_browse	Abe, Takayuki Otsubo, Shigeru Kimata, Naoki Okajima, Tomoki Otani, Yumi Murakami, Jun Kaneko, Iwakazu Miwa, Naoko Mineshima, Michio Tsuchiya, Ken Nitta, Kosaku Akiba, Takashi
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title_sort	changes in the ankle-brachial blood pressure index among hemodialysis patients
title_auth	Changes in the ankle-brachial blood pressure index among hemodialysis patients
abstract	Background The ankle-brachial blood pressure index (ABI) is an independent predictor of mortality in hemodialysis patients. In the present study, we investigated the factors that predict changes in the ABI in hemodialysis patients. Methods A total of 61 consecutive patients receiving maintenance hemodialysis who successfully underwent ABI examinations in 2005 and 2011 were enrolled in this study. The change in the ABI (2011 measurement versus 2005 measurement) was estimated. We set the baseline at 2011 and investigated the patient outcomes. Furthermore, we compared the change in the ABI and several clinical factors observed in 2005. Results The mean follow-up period was 3.1 ± 0.7 years. In the univariate Cox proportional hazard analysis, predictive variables for mortality included ABI (0.43 [0.25–0.64]; [per 0.1 increase]) and the change in the ABI (0.62 [0.49–0.79]; [per 0.1 increase]). Patient age was negatively correlated and the serum creatinine level was positively correlated with the change in the ABI (P = 0.030 and 0.022, respectively). Conclusions We confirmed that not only the value of the ABI itself but also the change in the ABI was a risk factor for mortality among hemodialysis patients. The change in the ABI was negatively correlated with age and was positively correlated with the serum creatinine level. Careful observation of the ABI is needed for old patients and patients with a low serum creatinine level. © The Author(s) 2016
abstractGer	Background The ankle-brachial blood pressure index (ABI) is an independent predictor of mortality in hemodialysis patients. In the present study, we investigated the factors that predict changes in the ABI in hemodialysis patients. Methods A total of 61 consecutive patients receiving maintenance hemodialysis who successfully underwent ABI examinations in 2005 and 2011 were enrolled in this study. The change in the ABI (2011 measurement versus 2005 measurement) was estimated. We set the baseline at 2011 and investigated the patient outcomes. Furthermore, we compared the change in the ABI and several clinical factors observed in 2005. Results The mean follow-up period was 3.1 ± 0.7 years. In the univariate Cox proportional hazard analysis, predictive variables for mortality included ABI (0.43 [0.25–0.64]; [per 0.1 increase]) and the change in the ABI (0.62 [0.49–0.79]; [per 0.1 increase]). Patient age was negatively correlated and the serum creatinine level was positively correlated with the change in the ABI (P = 0.030 and 0.022, respectively). Conclusions We confirmed that not only the value of the ABI itself but also the change in the ABI was a risk factor for mortality among hemodialysis patients. The change in the ABI was negatively correlated with age and was positively correlated with the serum creatinine level. Careful observation of the ABI is needed for old patients and patients with a low serum creatinine level. © The Author(s) 2016
abstract_unstemmed	Background The ankle-brachial blood pressure index (ABI) is an independent predictor of mortality in hemodialysis patients. In the present study, we investigated the factors that predict changes in the ABI in hemodialysis patients. Methods A total of 61 consecutive patients receiving maintenance hemodialysis who successfully underwent ABI examinations in 2005 and 2011 were enrolled in this study. The change in the ABI (2011 measurement versus 2005 measurement) was estimated. We set the baseline at 2011 and investigated the patient outcomes. Furthermore, we compared the change in the ABI and several clinical factors observed in 2005. Results The mean follow-up period was 3.1 ± 0.7 years. In the univariate Cox proportional hazard analysis, predictive variables for mortality included ABI (0.43 [0.25–0.64]; [per 0.1 increase]) and the change in the ABI (0.62 [0.49–0.79]; [per 0.1 increase]). Patient age was negatively correlated and the serum creatinine level was positively correlated with the change in the ABI (P = 0.030 and 0.022, respectively). Conclusions We confirmed that not only the value of the ABI itself but also the change in the ABI was a risk factor for mortality among hemodialysis patients. The change in the ABI was negatively correlated with age and was positively correlated with the serum creatinine level. Careful observation of the ABI is needed for old patients and patients with a low serum creatinine level. © The Author(s) 2016
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title_short	Changes in the ankle-brachial blood pressure index among hemodialysis patients
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author2	Otsubo, Shigeru Kimata, Naoki Okajima, Tomoki Otani, Yumi Murakami, Jun Kaneko, Iwakazu Miwa, Naoko Mineshima, Michio Tsuchiya, Ken Nitta, Kosaku Akiba, Takashi
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In the present study, we investigated the factors that predict changes in the ABI in hemodialysis patients. Methods A total of 61 consecutive patients receiving maintenance hemodialysis who successfully underwent ABI examinations in 2005 and 2011 were enrolled in this study. The change in the ABI (2011 measurement versus 2005 measurement) was estimated. We set the baseline at 2011 and investigated the patient outcomes. Furthermore, we compared the change in the ABI and several clinical factors observed in 2005. Results The mean follow-up period was 3.1 ± 0.7 years. In the univariate Cox proportional hazard analysis, predictive variables for mortality included ABI (0.43 [0.25–0.64]; [per 0.1 increase]) and the change in the ABI (0.62 [0.49–0.79]; [per 0.1 increase]). Patient age was negatively correlated and the serum creatinine level was positively correlated with the change in the ABI (P = 0.030 and 0.022, respectively). Conclusions We confirmed that not only the value of the ABI itself but also the change in the ABI was a risk factor for mortality among hemodialysis patients. The change in the ABI was negatively correlated with age and was positively correlated with the serum creatinine level. 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Changes in the ankle-brachial blood pressure index among hemodialysis patients

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