Geographic variation in radon and associated lung cancer risk in Canada
Abstract OBJECTIVE: Radon is an important risk factor for lung cancer. Here we use maps of the geographic variation in radon to estimate the lung cancer risk associated with living in high radon areas of Canada. METHODS: Geographic variation in radon was estimated using two mapping methods. The firs...
Ausführliche Beschreibung
Gespeichert in:
| Autor*in: |
Hystad, Perry [verfasserIn] |
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| Format: |
E-Artikel |
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| Sprache: |
Englisch |
| Erschienen: |
2014 |
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| Anmerkung: |
© The Canadian Public Health Association 2014 |
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| Übergeordnetes Werk: |
Enthalten in: Canadian journal of public health - [S.l.] : Springer, 1943, 105(2014), 1 vom: 01. Jan., Seite e4-e10 |
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| Übergeordnetes Werk: |
volume:105 ; year:2014 ; number:1 ; day:01 ; month:01 ; pages:e4-e10 |
| Links: |
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| DOI / URN: |
10.17269/cjph.105.4002 |
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| Katalog-ID: |
SPR038392658 |
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| 100 | 1 | |a Hystad, Perry |e verfasserin |4 aut | |
| 245 | 1 | 0 | |a Geographic variation in radon and associated lung cancer risk in Canada |
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| 520 | |a Abstract OBJECTIVE: Radon is an important risk factor for lung cancer. Here we use maps of the geographic variation in radon to estimate the lung cancer risk associated with living in high radon areas of Canada. METHODS: Geographic variation in radon was estimated using two mapping methods. The first used a Health Canada survey of 14,000 residential radon measurements aggregated to health regions, and the second, radon risk areas previously estimated from geology, sediment geochemistry and aerial gamma-ray spectrometry. Lung cancer risk associated with living in these radon areas was examined using a population-based case-control study of 2,390 lung cancer cases and 3,507 controls collected from 1994–1997 in eight Canadian provinces. Residential histories over a 20-year period were used in combination with the two mapping methods to estimate ecological radon exposures. Hierarchical logistic regression analyses were used to estimate odds ratios for lung cancer incidence, after adjusting for a comprehensive set of individual and geographic covariates. RESULTS: Across health regions in Canada, significant variation in average residential radon concentrations (range: 16–386 Bq/$ m^{3} $) and in high geological-based radon areas (range: 0–100%) is present. In multivariate models, a 50 Bq/$ m^{3} $ increase in average health region radon was associated with a 7% (95% CI: −6–21%) increase in the odds of lung cancer. For every 10 years that individuals lived in high radon geological areas, the odds of lung cancer increased by 11 % (95% CI: 1–23%). CONCLUSIONS: These findings provide further evidence that radon is an important risk factor for lung cancer and that risks are unevenly distributed across Canada. | ||
| 700 | 1 | |a Brauer, Michael |4 aut | |
| 700 | 1 | |a Demers, Paul A. |4 aut | |
| 700 | 1 | |a Johnson, Kenneth C. |4 aut | |
| 700 | 1 | |a Setton, Eleanor |4 aut | |
| 700 | 1 | |a Cervantes-Larios, Alejandro |4 aut | |
| 700 | 1 | |a Poplawski, Karla |4 aut | |
| 700 | 1 | |a McFarlane, Alana |4 aut | |
| 700 | 1 | |a Whitehead, Alan |4 aut | |
| 700 | 1 | |a Nicol, Anne-Marie |4 aut | |
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10.17269/cjph.105.4002 doi (DE-627)SPR038392658 (SPR)cjph.105.4002-e DE-627 ger DE-627 rakwb eng Hystad, Perry verfasserin aut Geographic variation in radon and associated lung cancer risk in Canada 2014 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier © The Canadian Public Health Association 2014 Abstract OBJECTIVE: Radon is an important risk factor for lung cancer. Here we use maps of the geographic variation in radon to estimate the lung cancer risk associated with living in high radon areas of Canada. METHODS: Geographic variation in radon was estimated using two mapping methods. The first used a Health Canada survey of 14,000 residential radon measurements aggregated to health regions, and the second, radon risk areas previously estimated from geology, sediment geochemistry and aerial gamma-ray spectrometry. Lung cancer risk associated with living in these radon areas was examined using a population-based case-control study of 2,390 lung cancer cases and 3,507 controls collected from 1994–1997 in eight Canadian provinces. Residential histories over a 20-year period were used in combination with the two mapping methods to estimate ecological radon exposures. Hierarchical logistic regression analyses were used to estimate odds ratios for lung cancer incidence, after adjusting for a comprehensive set of individual and geographic covariates. RESULTS: Across health regions in Canada, significant variation in average residential radon concentrations (range: 16–386 Bq/$ m^{3} $) and in high geological-based radon areas (range: 0–100%) is present. In multivariate models, a 50 Bq/$ m^{3} $ increase in average health region radon was associated with a 7% (95% CI: −6–21%) increase in the odds of lung cancer. For every 10 years that individuals lived in high radon geological areas, the odds of lung cancer increased by 11 % (95% CI: 1–23%). CONCLUSIONS: These findings provide further evidence that radon is an important risk factor for lung cancer and that risks are unevenly distributed across Canada. Brauer, Michael aut Demers, Paul A. aut Johnson, Kenneth C. aut Setton, Eleanor aut Cervantes-Larios, Alejandro aut Poplawski, Karla aut McFarlane, Alana aut Whitehead, Alan aut Nicol, Anne-Marie aut Enthalten in Canadian journal of public health [S.l.] : Springer, 1943 105(2014), 1 vom: 01. Jan., Seite e4-e10 (DE-627)654744041 (DE-600)2599345-8 1920-7476 nnns volume:105 year:2014 number:1 day:01 month:01 pages:e4-e10 https://dx.doi.org/10.17269/cjph.105.4002 lizenzpflichtig Volltext GBV_USEFLAG_A SYSFLAG_A GBV_SPRINGER SSG-OLC-PHA GBV_ILN_11 GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_32 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_70 GBV_ILN_73 GBV_ILN_74 GBV_ILN_90 GBV_ILN_95 GBV_ILN_100 GBV_ILN_101 GBV_ILN_105 GBV_ILN_110 GBV_ILN_138 GBV_ILN_150 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_171 GBV_ILN_187 GBV_ILN_206 GBV_ILN_213 GBV_ILN_224 GBV_ILN_230 GBV_ILN_250 GBV_ILN_266 GBV_ILN_281 GBV_ILN_285 GBV_ILN_293 GBV_ILN_370 GBV_ILN_374 GBV_ILN_602 GBV_ILN_636 GBV_ILN_702 GBV_ILN_2001 GBV_ILN_2003 GBV_ILN_2004 GBV_ILN_2005 GBV_ILN_2006 GBV_ILN_2007 GBV_ILN_2008 GBV_ILN_2009 GBV_ILN_2010 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2015 GBV_ILN_2018 GBV_ILN_2020 GBV_ILN_2021 GBV_ILN_2025 GBV_ILN_2026 GBV_ILN_2027 GBV_ILN_2031 GBV_ILN_2034 GBV_ILN_2037 GBV_ILN_2038 GBV_ILN_2039 GBV_ILN_2044 GBV_ILN_2048 GBV_ILN_2049 GBV_ILN_2050 GBV_ILN_2055 GBV_ILN_2056 GBV_ILN_2057 GBV_ILN_2059 GBV_ILN_2061 GBV_ILN_2064 GBV_ILN_2065 GBV_ILN_2068 GBV_ILN_2088 GBV_ILN_2093 GBV_ILN_2106 GBV_ILN_2107 GBV_ILN_2108 GBV_ILN_2110 GBV_ILN_2111 GBV_ILN_2112 GBV_ILN_2113 GBV_ILN_2118 GBV_ILN_2129 GBV_ILN_2143 GBV_ILN_2144 GBV_ILN_2147 GBV_ILN_2148 GBV_ILN_2152 GBV_ILN_2153 GBV_ILN_2188 GBV_ILN_2190 GBV_ILN_2232 GBV_ILN_2336 GBV_ILN_2446 GBV_ILN_2470 GBV_ILN_2472 GBV_ILN_2507 GBV_ILN_2522 GBV_ILN_2548 GBV_ILN_2949 GBV_ILN_2950 GBV_ILN_4012 GBV_ILN_4035 GBV_ILN_4037 GBV_ILN_4046 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4242 GBV_ILN_4246 GBV_ILN_4249 GBV_ILN_4251 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4326 GBV_ILN_4333 GBV_ILN_4334 GBV_ILN_4335 GBV_ILN_4336 GBV_ILN_4338 GBV_ILN_4346 GBV_ILN_4367 GBV_ILN_4393 GBV_ILN_4700 AR 105 2014 1 01 01 e4-e10 |
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10.17269/cjph.105.4002 doi (DE-627)SPR038392658 (SPR)cjph.105.4002-e DE-627 ger DE-627 rakwb eng Hystad, Perry verfasserin aut Geographic variation in radon and associated lung cancer risk in Canada 2014 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier © The Canadian Public Health Association 2014 Abstract OBJECTIVE: Radon is an important risk factor for lung cancer. Here we use maps of the geographic variation in radon to estimate the lung cancer risk associated with living in high radon areas of Canada. METHODS: Geographic variation in radon was estimated using two mapping methods. The first used a Health Canada survey of 14,000 residential radon measurements aggregated to health regions, and the second, radon risk areas previously estimated from geology, sediment geochemistry and aerial gamma-ray spectrometry. Lung cancer risk associated with living in these radon areas was examined using a population-based case-control study of 2,390 lung cancer cases and 3,507 controls collected from 1994–1997 in eight Canadian provinces. Residential histories over a 20-year period were used in combination with the two mapping methods to estimate ecological radon exposures. Hierarchical logistic regression analyses were used to estimate odds ratios for lung cancer incidence, after adjusting for a comprehensive set of individual and geographic covariates. RESULTS: Across health regions in Canada, significant variation in average residential radon concentrations (range: 16–386 Bq/$ m^{3} $) and in high geological-based radon areas (range: 0–100%) is present. In multivariate models, a 50 Bq/$ m^{3} $ increase in average health region radon was associated with a 7% (95% CI: −6–21%) increase in the odds of lung cancer. For every 10 years that individuals lived in high radon geological areas, the odds of lung cancer increased by 11 % (95% CI: 1–23%). CONCLUSIONS: These findings provide further evidence that radon is an important risk factor for lung cancer and that risks are unevenly distributed across Canada. Brauer, Michael aut Demers, Paul A. aut Johnson, Kenneth C. aut Setton, Eleanor aut Cervantes-Larios, Alejandro aut Poplawski, Karla aut McFarlane, Alana aut Whitehead, Alan aut Nicol, Anne-Marie aut Enthalten in Canadian journal of public health [S.l.] : Springer, 1943 105(2014), 1 vom: 01. Jan., Seite e4-e10 (DE-627)654744041 (DE-600)2599345-8 1920-7476 nnns volume:105 year:2014 number:1 day:01 month:01 pages:e4-e10 https://dx.doi.org/10.17269/cjph.105.4002 lizenzpflichtig Volltext GBV_USEFLAG_A SYSFLAG_A GBV_SPRINGER SSG-OLC-PHA GBV_ILN_11 GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_32 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_70 GBV_ILN_73 GBV_ILN_74 GBV_ILN_90 GBV_ILN_95 GBV_ILN_100 GBV_ILN_101 GBV_ILN_105 GBV_ILN_110 GBV_ILN_138 GBV_ILN_150 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_171 GBV_ILN_187 GBV_ILN_206 GBV_ILN_213 GBV_ILN_224 GBV_ILN_230 GBV_ILN_250 GBV_ILN_266 GBV_ILN_281 GBV_ILN_285 GBV_ILN_293 GBV_ILN_370 GBV_ILN_374 GBV_ILN_602 GBV_ILN_636 GBV_ILN_702 GBV_ILN_2001 GBV_ILN_2003 GBV_ILN_2004 GBV_ILN_2005 GBV_ILN_2006 GBV_ILN_2007 GBV_ILN_2008 GBV_ILN_2009 GBV_ILN_2010 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2015 GBV_ILN_2018 GBV_ILN_2020 GBV_ILN_2021 GBV_ILN_2025 GBV_ILN_2026 GBV_ILN_2027 GBV_ILN_2031 GBV_ILN_2034 GBV_ILN_2037 GBV_ILN_2038 GBV_ILN_2039 GBV_ILN_2044 GBV_ILN_2048 GBV_ILN_2049 GBV_ILN_2050 GBV_ILN_2055 GBV_ILN_2056 GBV_ILN_2057 GBV_ILN_2059 GBV_ILN_2061 GBV_ILN_2064 GBV_ILN_2065 GBV_ILN_2068 GBV_ILN_2088 GBV_ILN_2093 GBV_ILN_2106 GBV_ILN_2107 GBV_ILN_2108 GBV_ILN_2110 GBV_ILN_2111 GBV_ILN_2112 GBV_ILN_2113 GBV_ILN_2118 GBV_ILN_2129 GBV_ILN_2143 GBV_ILN_2144 GBV_ILN_2147 GBV_ILN_2148 GBV_ILN_2152 GBV_ILN_2153 GBV_ILN_2188 GBV_ILN_2190 GBV_ILN_2232 GBV_ILN_2336 GBV_ILN_2446 GBV_ILN_2470 GBV_ILN_2472 GBV_ILN_2507 GBV_ILN_2522 GBV_ILN_2548 GBV_ILN_2949 GBV_ILN_2950 GBV_ILN_4012 GBV_ILN_4035 GBV_ILN_4037 GBV_ILN_4046 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4242 GBV_ILN_4246 GBV_ILN_4249 GBV_ILN_4251 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4326 GBV_ILN_4333 GBV_ILN_4334 GBV_ILN_4335 GBV_ILN_4336 GBV_ILN_4338 GBV_ILN_4346 GBV_ILN_4367 GBV_ILN_4393 GBV_ILN_4700 AR 105 2014 1 01 01 e4-e10 |
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10.17269/cjph.105.4002 doi (DE-627)SPR038392658 (SPR)cjph.105.4002-e DE-627 ger DE-627 rakwb eng Hystad, Perry verfasserin aut Geographic variation in radon and associated lung cancer risk in Canada 2014 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier © The Canadian Public Health Association 2014 Abstract OBJECTIVE: Radon is an important risk factor for lung cancer. Here we use maps of the geographic variation in radon to estimate the lung cancer risk associated with living in high radon areas of Canada. METHODS: Geographic variation in radon was estimated using two mapping methods. The first used a Health Canada survey of 14,000 residential radon measurements aggregated to health regions, and the second, radon risk areas previously estimated from geology, sediment geochemistry and aerial gamma-ray spectrometry. Lung cancer risk associated with living in these radon areas was examined using a population-based case-control study of 2,390 lung cancer cases and 3,507 controls collected from 1994–1997 in eight Canadian provinces. Residential histories over a 20-year period were used in combination with the two mapping methods to estimate ecological radon exposures. Hierarchical logistic regression analyses were used to estimate odds ratios for lung cancer incidence, after adjusting for a comprehensive set of individual and geographic covariates. RESULTS: Across health regions in Canada, significant variation in average residential radon concentrations (range: 16–386 Bq/$ m^{3} $) and in high geological-based radon areas (range: 0–100%) is present. In multivariate models, a 50 Bq/$ m^{3} $ increase in average health region radon was associated with a 7% (95% CI: −6–21%) increase in the odds of lung cancer. For every 10 years that individuals lived in high radon geological areas, the odds of lung cancer increased by 11 % (95% CI: 1–23%). CONCLUSIONS: These findings provide further evidence that radon is an important risk factor for lung cancer and that risks are unevenly distributed across Canada. Brauer, Michael aut Demers, Paul A. aut Johnson, Kenneth C. aut Setton, Eleanor aut Cervantes-Larios, Alejandro aut Poplawski, Karla aut McFarlane, Alana aut Whitehead, Alan aut Nicol, Anne-Marie aut Enthalten in Canadian journal of public health [S.l.] : Springer, 1943 105(2014), 1 vom: 01. Jan., Seite e4-e10 (DE-627)654744041 (DE-600)2599345-8 1920-7476 nnns volume:105 year:2014 number:1 day:01 month:01 pages:e4-e10 https://dx.doi.org/10.17269/cjph.105.4002 lizenzpflichtig Volltext GBV_USEFLAG_A SYSFLAG_A GBV_SPRINGER SSG-OLC-PHA GBV_ILN_11 GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_32 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_70 GBV_ILN_73 GBV_ILN_74 GBV_ILN_90 GBV_ILN_95 GBV_ILN_100 GBV_ILN_101 GBV_ILN_105 GBV_ILN_110 GBV_ILN_138 GBV_ILN_150 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_171 GBV_ILN_187 GBV_ILN_206 GBV_ILN_213 GBV_ILN_224 GBV_ILN_230 GBV_ILN_250 GBV_ILN_266 GBV_ILN_281 GBV_ILN_285 GBV_ILN_293 GBV_ILN_370 GBV_ILN_374 GBV_ILN_602 GBV_ILN_636 GBV_ILN_702 GBV_ILN_2001 GBV_ILN_2003 GBV_ILN_2004 GBV_ILN_2005 GBV_ILN_2006 GBV_ILN_2007 GBV_ILN_2008 GBV_ILN_2009 GBV_ILN_2010 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2015 GBV_ILN_2018 GBV_ILN_2020 GBV_ILN_2021 GBV_ILN_2025 GBV_ILN_2026 GBV_ILN_2027 GBV_ILN_2031 GBV_ILN_2034 GBV_ILN_2037 GBV_ILN_2038 GBV_ILN_2039 GBV_ILN_2044 GBV_ILN_2048 GBV_ILN_2049 GBV_ILN_2050 GBV_ILN_2055 GBV_ILN_2056 GBV_ILN_2057 GBV_ILN_2059 GBV_ILN_2061 GBV_ILN_2064 GBV_ILN_2065 GBV_ILN_2068 GBV_ILN_2088 GBV_ILN_2093 GBV_ILN_2106 GBV_ILN_2107 GBV_ILN_2108 GBV_ILN_2110 GBV_ILN_2111 GBV_ILN_2112 GBV_ILN_2113 GBV_ILN_2118 GBV_ILN_2129 GBV_ILN_2143 GBV_ILN_2144 GBV_ILN_2147 GBV_ILN_2148 GBV_ILN_2152 GBV_ILN_2153 GBV_ILN_2188 GBV_ILN_2190 GBV_ILN_2232 GBV_ILN_2336 GBV_ILN_2446 GBV_ILN_2470 GBV_ILN_2472 GBV_ILN_2507 GBV_ILN_2522 GBV_ILN_2548 GBV_ILN_2949 GBV_ILN_2950 GBV_ILN_4012 GBV_ILN_4035 GBV_ILN_4037 GBV_ILN_4046 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4242 GBV_ILN_4246 GBV_ILN_4249 GBV_ILN_4251 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4326 GBV_ILN_4333 GBV_ILN_4334 GBV_ILN_4335 GBV_ILN_4336 GBV_ILN_4338 GBV_ILN_4346 GBV_ILN_4367 GBV_ILN_4393 GBV_ILN_4700 AR 105 2014 1 01 01 e4-e10 |
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10.17269/cjph.105.4002 doi (DE-627)SPR038392658 (SPR)cjph.105.4002-e DE-627 ger DE-627 rakwb eng Hystad, Perry verfasserin aut Geographic variation in radon and associated lung cancer risk in Canada 2014 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier © The Canadian Public Health Association 2014 Abstract OBJECTIVE: Radon is an important risk factor for lung cancer. Here we use maps of the geographic variation in radon to estimate the lung cancer risk associated with living in high radon areas of Canada. METHODS: Geographic variation in radon was estimated using two mapping methods. The first used a Health Canada survey of 14,000 residential radon measurements aggregated to health regions, and the second, radon risk areas previously estimated from geology, sediment geochemistry and aerial gamma-ray spectrometry. Lung cancer risk associated with living in these radon areas was examined using a population-based case-control study of 2,390 lung cancer cases and 3,507 controls collected from 1994–1997 in eight Canadian provinces. Residential histories over a 20-year period were used in combination with the two mapping methods to estimate ecological radon exposures. Hierarchical logistic regression analyses were used to estimate odds ratios for lung cancer incidence, after adjusting for a comprehensive set of individual and geographic covariates. RESULTS: Across health regions in Canada, significant variation in average residential radon concentrations (range: 16–386 Bq/$ m^{3} $) and in high geological-based radon areas (range: 0–100%) is present. In multivariate models, a 50 Bq/$ m^{3} $ increase in average health region radon was associated with a 7% (95% CI: −6–21%) increase in the odds of lung cancer. For every 10 years that individuals lived in high radon geological areas, the odds of lung cancer increased by 11 % (95% CI: 1–23%). CONCLUSIONS: These findings provide further evidence that radon is an important risk factor for lung cancer and that risks are unevenly distributed across Canada. Brauer, Michael aut Demers, Paul A. aut Johnson, Kenneth C. aut Setton, Eleanor aut Cervantes-Larios, Alejandro aut Poplawski, Karla aut McFarlane, Alana aut Whitehead, Alan aut Nicol, Anne-Marie aut Enthalten in Canadian journal of public health [S.l.] : Springer, 1943 105(2014), 1 vom: 01. Jan., Seite e4-e10 (DE-627)654744041 (DE-600)2599345-8 1920-7476 nnns volume:105 year:2014 number:1 day:01 month:01 pages:e4-e10 https://dx.doi.org/10.17269/cjph.105.4002 lizenzpflichtig Volltext GBV_USEFLAG_A SYSFLAG_A GBV_SPRINGER SSG-OLC-PHA GBV_ILN_11 GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_32 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_70 GBV_ILN_73 GBV_ILN_74 GBV_ILN_90 GBV_ILN_95 GBV_ILN_100 GBV_ILN_101 GBV_ILN_105 GBV_ILN_110 GBV_ILN_138 GBV_ILN_150 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_171 GBV_ILN_187 GBV_ILN_206 GBV_ILN_213 GBV_ILN_224 GBV_ILN_230 GBV_ILN_250 GBV_ILN_266 GBV_ILN_281 GBV_ILN_285 GBV_ILN_293 GBV_ILN_370 GBV_ILN_374 GBV_ILN_602 GBV_ILN_636 GBV_ILN_702 GBV_ILN_2001 GBV_ILN_2003 GBV_ILN_2004 GBV_ILN_2005 GBV_ILN_2006 GBV_ILN_2007 GBV_ILN_2008 GBV_ILN_2009 GBV_ILN_2010 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2015 GBV_ILN_2018 GBV_ILN_2020 GBV_ILN_2021 GBV_ILN_2025 GBV_ILN_2026 GBV_ILN_2027 GBV_ILN_2031 GBV_ILN_2034 GBV_ILN_2037 GBV_ILN_2038 GBV_ILN_2039 GBV_ILN_2044 GBV_ILN_2048 GBV_ILN_2049 GBV_ILN_2050 GBV_ILN_2055 GBV_ILN_2056 GBV_ILN_2057 GBV_ILN_2059 GBV_ILN_2061 GBV_ILN_2064 GBV_ILN_2065 GBV_ILN_2068 GBV_ILN_2088 GBV_ILN_2093 GBV_ILN_2106 GBV_ILN_2107 GBV_ILN_2108 GBV_ILN_2110 GBV_ILN_2111 GBV_ILN_2112 GBV_ILN_2113 GBV_ILN_2118 GBV_ILN_2129 GBV_ILN_2143 GBV_ILN_2144 GBV_ILN_2147 GBV_ILN_2148 GBV_ILN_2152 GBV_ILN_2153 GBV_ILN_2188 GBV_ILN_2190 GBV_ILN_2232 GBV_ILN_2336 GBV_ILN_2446 GBV_ILN_2470 GBV_ILN_2472 GBV_ILN_2507 GBV_ILN_2522 GBV_ILN_2548 GBV_ILN_2949 GBV_ILN_2950 GBV_ILN_4012 GBV_ILN_4035 GBV_ILN_4037 GBV_ILN_4046 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4242 GBV_ILN_4246 GBV_ILN_4249 GBV_ILN_4251 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4326 GBV_ILN_4333 GBV_ILN_4334 GBV_ILN_4335 GBV_ILN_4336 GBV_ILN_4338 GBV_ILN_4346 GBV_ILN_4367 GBV_ILN_4393 GBV_ILN_4700 AR 105 2014 1 01 01 e4-e10 |
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10.17269/cjph.105.4002 doi (DE-627)SPR038392658 (SPR)cjph.105.4002-e DE-627 ger DE-627 rakwb eng Hystad, Perry verfasserin aut Geographic variation in radon and associated lung cancer risk in Canada 2014 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier © The Canadian Public Health Association 2014 Abstract OBJECTIVE: Radon is an important risk factor for lung cancer. Here we use maps of the geographic variation in radon to estimate the lung cancer risk associated with living in high radon areas of Canada. METHODS: Geographic variation in radon was estimated using two mapping methods. The first used a Health Canada survey of 14,000 residential radon measurements aggregated to health regions, and the second, radon risk areas previously estimated from geology, sediment geochemistry and aerial gamma-ray spectrometry. Lung cancer risk associated with living in these radon areas was examined using a population-based case-control study of 2,390 lung cancer cases and 3,507 controls collected from 1994–1997 in eight Canadian provinces. Residential histories over a 20-year period were used in combination with the two mapping methods to estimate ecological radon exposures. Hierarchical logistic regression analyses were used to estimate odds ratios for lung cancer incidence, after adjusting for a comprehensive set of individual and geographic covariates. RESULTS: Across health regions in Canada, significant variation in average residential radon concentrations (range: 16–386 Bq/$ m^{3} $) and in high geological-based radon areas (range: 0–100%) is present. In multivariate models, a 50 Bq/$ m^{3} $ increase in average health region radon was associated with a 7% (95% CI: −6–21%) increase in the odds of lung cancer. For every 10 years that individuals lived in high radon geological areas, the odds of lung cancer increased by 11 % (95% CI: 1–23%). CONCLUSIONS: These findings provide further evidence that radon is an important risk factor for lung cancer and that risks are unevenly distributed across Canada. Brauer, Michael aut Demers, Paul A. aut Johnson, Kenneth C. aut Setton, Eleanor aut Cervantes-Larios, Alejandro aut Poplawski, Karla aut McFarlane, Alana aut Whitehead, Alan aut Nicol, Anne-Marie aut Enthalten in Canadian journal of public health [S.l.] : Springer, 1943 105(2014), 1 vom: 01. Jan., Seite e4-e10 (DE-627)654744041 (DE-600)2599345-8 1920-7476 nnns volume:105 year:2014 number:1 day:01 month:01 pages:e4-e10 https://dx.doi.org/10.17269/cjph.105.4002 lizenzpflichtig Volltext GBV_USEFLAG_A SYSFLAG_A GBV_SPRINGER SSG-OLC-PHA GBV_ILN_11 GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_32 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_70 GBV_ILN_73 GBV_ILN_74 GBV_ILN_90 GBV_ILN_95 GBV_ILN_100 GBV_ILN_101 GBV_ILN_105 GBV_ILN_110 GBV_ILN_138 GBV_ILN_150 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_171 GBV_ILN_187 GBV_ILN_206 GBV_ILN_213 GBV_ILN_224 GBV_ILN_230 GBV_ILN_250 GBV_ILN_266 GBV_ILN_281 GBV_ILN_285 GBV_ILN_293 GBV_ILN_370 GBV_ILN_374 GBV_ILN_602 GBV_ILN_636 GBV_ILN_702 GBV_ILN_2001 GBV_ILN_2003 GBV_ILN_2004 GBV_ILN_2005 GBV_ILN_2006 GBV_ILN_2007 GBV_ILN_2008 GBV_ILN_2009 GBV_ILN_2010 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2015 GBV_ILN_2018 GBV_ILN_2020 GBV_ILN_2021 GBV_ILN_2025 GBV_ILN_2026 GBV_ILN_2027 GBV_ILN_2031 GBV_ILN_2034 GBV_ILN_2037 GBV_ILN_2038 GBV_ILN_2039 GBV_ILN_2044 GBV_ILN_2048 GBV_ILN_2049 GBV_ILN_2050 GBV_ILN_2055 GBV_ILN_2056 GBV_ILN_2057 GBV_ILN_2059 GBV_ILN_2061 GBV_ILN_2064 GBV_ILN_2065 GBV_ILN_2068 GBV_ILN_2088 GBV_ILN_2093 GBV_ILN_2106 GBV_ILN_2107 GBV_ILN_2108 GBV_ILN_2110 GBV_ILN_2111 GBV_ILN_2112 GBV_ILN_2113 GBV_ILN_2118 GBV_ILN_2129 GBV_ILN_2143 GBV_ILN_2144 GBV_ILN_2147 GBV_ILN_2148 GBV_ILN_2152 GBV_ILN_2153 GBV_ILN_2188 GBV_ILN_2190 GBV_ILN_2232 GBV_ILN_2336 GBV_ILN_2446 GBV_ILN_2470 GBV_ILN_2472 GBV_ILN_2507 GBV_ILN_2522 GBV_ILN_2548 GBV_ILN_2949 GBV_ILN_2950 GBV_ILN_4012 GBV_ILN_4035 GBV_ILN_4037 GBV_ILN_4046 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4242 GBV_ILN_4246 GBV_ILN_4249 GBV_ILN_4251 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4326 GBV_ILN_4333 GBV_ILN_4334 GBV_ILN_4335 GBV_ILN_4336 GBV_ILN_4338 GBV_ILN_4346 GBV_ILN_4367 GBV_ILN_4393 GBV_ILN_4700 AR 105 2014 1 01 01 e4-e10 |
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Hystad, Perry @@aut@@ Brauer, Michael @@aut@@ Demers, Paul A. @@aut@@ Johnson, Kenneth C. @@aut@@ Setton, Eleanor @@aut@@ Cervantes-Larios, Alejandro @@aut@@ Poplawski, Karla @@aut@@ McFarlane, Alana @@aut@@ Whitehead, Alan @@aut@@ Nicol, Anne-Marie @@aut@@ |
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<?xml version="1.0" encoding="UTF-8"?><collection xmlns="http://www.loc.gov/MARC21/slim"><record><leader>01000caa a22002652 4500</leader><controlfield tag="001">SPR038392658</controlfield><controlfield tag="003">DE-627</controlfield><controlfield tag="005">20230519155355.0</controlfield><controlfield tag="007">cr uuu---uuuuu</controlfield><controlfield tag="008">201007s2014 xx |||||o 00| ||eng c</controlfield><datafield tag="024" ind1="7" ind2=" "><subfield code="a">10.17269/cjph.105.4002</subfield><subfield code="2">doi</subfield></datafield><datafield tag="035" ind1=" " ind2=" "><subfield code="a">(DE-627)SPR038392658</subfield></datafield><datafield tag="035" ind1=" " ind2=" "><subfield code="a">(SPR)cjph.105.4002-e</subfield></datafield><datafield tag="040" ind1=" " ind2=" "><subfield code="a">DE-627</subfield><subfield code="b">ger</subfield><subfield code="c">DE-627</subfield><subfield code="e">rakwb</subfield></datafield><datafield tag="041" ind1=" " ind2=" "><subfield code="a">eng</subfield></datafield><datafield tag="100" ind1="1" ind2=" "><subfield code="a">Hystad, Perry</subfield><subfield code="e">verfasserin</subfield><subfield code="4">aut</subfield></datafield><datafield tag="245" ind1="1" ind2="0"><subfield code="a">Geographic variation in radon and associated lung cancer risk in Canada</subfield></datafield><datafield tag="264" ind1=" " ind2="1"><subfield code="c">2014</subfield></datafield><datafield tag="336" ind1=" " ind2=" "><subfield code="a">Text</subfield><subfield code="b">txt</subfield><subfield code="2">rdacontent</subfield></datafield><datafield tag="337" ind1=" " ind2=" "><subfield code="a">Computermedien</subfield><subfield code="b">c</subfield><subfield code="2">rdamedia</subfield></datafield><datafield tag="338" ind1=" " ind2=" "><subfield code="a">Online-Ressource</subfield><subfield code="b">cr</subfield><subfield code="2">rdacarrier</subfield></datafield><datafield tag="500" ind1=" " ind2=" "><subfield code="a">© The Canadian Public Health Association 2014</subfield></datafield><datafield tag="520" ind1=" " ind2=" "><subfield code="a">Abstract OBJECTIVE: Radon is an important risk factor for lung cancer. Here we use maps of the geographic variation in radon to estimate the lung cancer risk associated with living in high radon areas of Canada. METHODS: Geographic variation in radon was estimated using two mapping methods. The first used a Health Canada survey of 14,000 residential radon measurements aggregated to health regions, and the second, radon risk areas previously estimated from geology, sediment geochemistry and aerial gamma-ray spectrometry. Lung cancer risk associated with living in these radon areas was examined using a population-based case-control study of 2,390 lung cancer cases and 3,507 controls collected from 1994–1997 in eight Canadian provinces. Residential histories over a 20-year period were used in combination with the two mapping methods to estimate ecological radon exposures. Hierarchical logistic regression analyses were used to estimate odds ratios for lung cancer incidence, after adjusting for a comprehensive set of individual and geographic covariates. RESULTS: Across health regions in Canada, significant variation in average residential radon concentrations (range: 16–386 Bq/$ m^{3} $) and in high geological-based radon areas (range: 0–100%) is present. In multivariate models, a 50 Bq/$ m^{3} $ increase in average health region radon was associated with a 7% (95% CI: −6–21%) increase in the odds of lung cancer. For every 10 years that individuals lived in high radon geological areas, the odds of lung cancer increased by 11 % (95% CI: 1–23%). CONCLUSIONS: These findings provide further evidence that radon is an important risk factor for lung cancer and that risks are unevenly distributed across Canada.</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Brauer, Michael</subfield><subfield code="4">aut</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Demers, Paul A.</subfield><subfield code="4">aut</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Johnson, Kenneth C.</subfield><subfield code="4">aut</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Setton, Eleanor</subfield><subfield code="4">aut</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Cervantes-Larios, Alejandro</subfield><subfield code="4">aut</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Poplawski, Karla</subfield><subfield code="4">aut</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">McFarlane, Alana</subfield><subfield code="4">aut</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Whitehead, Alan</subfield><subfield code="4">aut</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Nicol, Anne-Marie</subfield><subfield code="4">aut</subfield></datafield><datafield tag="773" ind1="0" ind2="8"><subfield code="i">Enthalten in</subfield><subfield code="t">Canadian journal of public health</subfield><subfield code="d">[S.l.] : Springer, 1943</subfield><subfield code="g">105(2014), 1 vom: 01. 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Geographic variation in radon and associated lung cancer risk in Canada |
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Geographic variation in radon and associated lung cancer risk in Canada |
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Geographic variation in radon and associated lung cancer risk in Canada |
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Hystad, Perry Brauer, Michael Demers, Paul A. Johnson, Kenneth C. Setton, Eleanor Cervantes-Larios, Alejandro Poplawski, Karla McFarlane, Alana Whitehead, Alan Nicol, Anne-Marie |
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geographic variation in radon and associated lung cancer risk in canada |
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Geographic variation in radon and associated lung cancer risk in Canada |
| abstract |
Abstract OBJECTIVE: Radon is an important risk factor for lung cancer. Here we use maps of the geographic variation in radon to estimate the lung cancer risk associated with living in high radon areas of Canada. METHODS: Geographic variation in radon was estimated using two mapping methods. The first used a Health Canada survey of 14,000 residential radon measurements aggregated to health regions, and the second, radon risk areas previously estimated from geology, sediment geochemistry and aerial gamma-ray spectrometry. Lung cancer risk associated with living in these radon areas was examined using a population-based case-control study of 2,390 lung cancer cases and 3,507 controls collected from 1994–1997 in eight Canadian provinces. Residential histories over a 20-year period were used in combination with the two mapping methods to estimate ecological radon exposures. Hierarchical logistic regression analyses were used to estimate odds ratios for lung cancer incidence, after adjusting for a comprehensive set of individual and geographic covariates. RESULTS: Across health regions in Canada, significant variation in average residential radon concentrations (range: 16–386 Bq/$ m^{3} $) and in high geological-based radon areas (range: 0–100%) is present. In multivariate models, a 50 Bq/$ m^{3} $ increase in average health region radon was associated with a 7% (95% CI: −6–21%) increase in the odds of lung cancer. For every 10 years that individuals lived in high radon geological areas, the odds of lung cancer increased by 11 % (95% CI: 1–23%). CONCLUSIONS: These findings provide further evidence that radon is an important risk factor for lung cancer and that risks are unevenly distributed across Canada. © The Canadian Public Health Association 2014 |
| abstractGer |
Abstract OBJECTIVE: Radon is an important risk factor for lung cancer. Here we use maps of the geographic variation in radon to estimate the lung cancer risk associated with living in high radon areas of Canada. METHODS: Geographic variation in radon was estimated using two mapping methods. The first used a Health Canada survey of 14,000 residential radon measurements aggregated to health regions, and the second, radon risk areas previously estimated from geology, sediment geochemistry and aerial gamma-ray spectrometry. Lung cancer risk associated with living in these radon areas was examined using a population-based case-control study of 2,390 lung cancer cases and 3,507 controls collected from 1994–1997 in eight Canadian provinces. Residential histories over a 20-year period were used in combination with the two mapping methods to estimate ecological radon exposures. Hierarchical logistic regression analyses were used to estimate odds ratios for lung cancer incidence, after adjusting for a comprehensive set of individual and geographic covariates. RESULTS: Across health regions in Canada, significant variation in average residential radon concentrations (range: 16–386 Bq/$ m^{3} $) and in high geological-based radon areas (range: 0–100%) is present. In multivariate models, a 50 Bq/$ m^{3} $ increase in average health region radon was associated with a 7% (95% CI: −6–21%) increase in the odds of lung cancer. For every 10 years that individuals lived in high radon geological areas, the odds of lung cancer increased by 11 % (95% CI: 1–23%). CONCLUSIONS: These findings provide further evidence that radon is an important risk factor for lung cancer and that risks are unevenly distributed across Canada. © The Canadian Public Health Association 2014 |
| abstract_unstemmed |
Abstract OBJECTIVE: Radon is an important risk factor for lung cancer. Here we use maps of the geographic variation in radon to estimate the lung cancer risk associated with living in high radon areas of Canada. METHODS: Geographic variation in radon was estimated using two mapping methods. The first used a Health Canada survey of 14,000 residential radon measurements aggregated to health regions, and the second, radon risk areas previously estimated from geology, sediment geochemistry and aerial gamma-ray spectrometry. Lung cancer risk associated with living in these radon areas was examined using a population-based case-control study of 2,390 lung cancer cases and 3,507 controls collected from 1994–1997 in eight Canadian provinces. Residential histories over a 20-year period were used in combination with the two mapping methods to estimate ecological radon exposures. Hierarchical logistic regression analyses were used to estimate odds ratios for lung cancer incidence, after adjusting for a comprehensive set of individual and geographic covariates. RESULTS: Across health regions in Canada, significant variation in average residential radon concentrations (range: 16–386 Bq/$ m^{3} $) and in high geological-based radon areas (range: 0–100%) is present. In multivariate models, a 50 Bq/$ m^{3} $ increase in average health region radon was associated with a 7% (95% CI: −6–21%) increase in the odds of lung cancer. For every 10 years that individuals lived in high radon geological areas, the odds of lung cancer increased by 11 % (95% CI: 1–23%). CONCLUSIONS: These findings provide further evidence that radon is an important risk factor for lung cancer and that risks are unevenly distributed across Canada. © The Canadian Public Health Association 2014 |
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Geographic variation in radon and associated lung cancer risk in Canada |
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https://dx.doi.org/10.17269/cjph.105.4002 |
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Brauer, Michael Demers, Paul A. Johnson, Kenneth C. Setton, Eleanor Cervantes-Larios, Alejandro Poplawski, Karla McFarlane, Alana Whitehead, Alan Nicol, Anne-Marie |
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Brauer, Michael Demers, Paul A. Johnson, Kenneth C. Setton, Eleanor Cervantes-Larios, Alejandro Poplawski, Karla McFarlane, Alana Whitehead, Alan Nicol, Anne-Marie |
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2024-07-03T17:49:15.729Z |
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| score |
7.399617 |