The Substantial Clinical Benefit Threshold for SRS-22R Domains After Surgical Treatment of Adult Spinal Deformity
Study Design Longitudinal cohort. Objectives To determine Substantial Clinical Benefit (SCB) thresholds for the SRS22R domains in patients undergoing adult spinal deformity surgery. Summary of Background Data The Scoliosis Research Society 22R (SRS22R) has been shown to be reliable, valid, and respo...
Ausführliche Beschreibung
Gespeichert in:
| Autor*in: |
Crawford, Charles H. [verfasserIn] |
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| Format: |
E-Artikel |
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| Sprache: |
Englisch |
| Erschienen: |
2016 |
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| Schlagwörter: |
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| Anmerkung: |
© Scoliosis Research Society 2016 |
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| Übergeordnetes Werk: |
Enthalten in: Spine deformity - Amsterdam [u.a.] : Elsevier, 2013, 4(2016), 5 vom: Sept., Seite 373-377 |
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| Übergeordnetes Werk: |
volume:4 ; year:2016 ; number:5 ; month:09 ; pages:373-377 |
| Links: |
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| DOI / URN: |
10.1016/j.jspd.2016.05.001 |
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SPR038869772 |
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| 520 | |a Study Design Longitudinal cohort. Objectives To determine Substantial Clinical Benefit (SCB) thresholds for the SRS22R domains in patients undergoing adult spinal deformity surgery. Summary of Background Data The Scoliosis Research Society 22R (SRS22R) has been shown to be reliable, valid, and responsive to change in adult spinal deformity patients. Although the minimal clinically important difference (MCID) is commonly used to quantify a threshold of improvement, it could be considered a floor value rather than a goal. Methods Patients enrolled in a prospective database of adult spinal deformity undergoing surgery with complete SRS22R preoperation and the SRS30 one-year after surgery were identified. One-year postoperative answers to the last 8 questions of the SRS30 were used as anchors to determine the SCB for the Appearance and Activity domains, Subtotal and Total Score using ROC Curve analysis. Results The sample population consisted of 1,422 patients; 83% were females. Mean age was 53 ± 16 years. Mean preoperative SRS22R Appearance score was 2.50 ± 0.73 improving to 3.62 ± 0.84 at one year postoperative. Mean preoperative SRS22R Activity score was 2.96 ± 0.59 improving to 3.33 ± 0.80 at one year postoperative. Mean preoperative SRS22R Pain score was 2.73 ± 0.92 improving to 3.60 ± 0.93 at one year postoperative. Mean preoperative SRS22R Subtotal was 2.56 ± 0.66 improving to 3.11 ± 0.80 at one year postoperative. There was a statistically significant difference in domain scores among the responses to the anchors (p <.001). Based on ROC analysis, SCB was 1.60 for Appearance, 0.87 for Activity, 0.69 for Subtotal, and 0.94 for Total score. Conclusion The results of the current study in an adult spinal deformity population undergoing surgical treatment show SRS22R SCB values of 1.60 for Appearance, 0.87 for Activity, 0.69 for Subtotal, and 0.94 for Total score. These SCB thresholds can be used to quantify the clinical significance of health status change in the surgical management of adult spinal deformity. Level of Evidence Level II. | ||
| 650 | 4 | |a Adult spinal deformity |7 (dpeaa)DE-He213 | |
| 650 | 4 | |a SRS-22R |7 (dpeaa)DE-He213 | |
| 650 | 4 | |a Clinical outcomes |7 (dpeaa)DE-He213 | |
| 650 | 4 | |a Substantial clinical benefit |7 (dpeaa)DE-He213 | |
| 700 | 1 | |a Glassman, Steven D. |4 aut | |
| 700 | 1 | |a Bridwell, Keith H. |4 aut | |
| 700 | 1 | |a Carreon, Leah Y. |4 aut | |
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10.1016/j.jspd.2016.05.001 doi (DE-627)SPR038869772 (SPR)j.jspd.2016.05.001-e DE-627 ger DE-627 rakwb eng Crawford, Charles H. verfasserin aut The Substantial Clinical Benefit Threshold for SRS-22R Domains After Surgical Treatment of Adult Spinal Deformity 2016 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier © Scoliosis Research Society 2016 Study Design Longitudinal cohort. Objectives To determine Substantial Clinical Benefit (SCB) thresholds for the SRS22R domains in patients undergoing adult spinal deformity surgery. Summary of Background Data The Scoliosis Research Society 22R (SRS22R) has been shown to be reliable, valid, and responsive to change in adult spinal deformity patients. Although the minimal clinically important difference (MCID) is commonly used to quantify a threshold of improvement, it could be considered a floor value rather than a goal. Methods Patients enrolled in a prospective database of adult spinal deformity undergoing surgery with complete SRS22R preoperation and the SRS30 one-year after surgery were identified. One-year postoperative answers to the last 8 questions of the SRS30 were used as anchors to determine the SCB for the Appearance and Activity domains, Subtotal and Total Score using ROC Curve analysis. Results The sample population consisted of 1,422 patients; 83% were females. Mean age was 53 ± 16 years. Mean preoperative SRS22R Appearance score was 2.50 ± 0.73 improving to 3.62 ± 0.84 at one year postoperative. Mean preoperative SRS22R Activity score was 2.96 ± 0.59 improving to 3.33 ± 0.80 at one year postoperative. Mean preoperative SRS22R Pain score was 2.73 ± 0.92 improving to 3.60 ± 0.93 at one year postoperative. Mean preoperative SRS22R Subtotal was 2.56 ± 0.66 improving to 3.11 ± 0.80 at one year postoperative. There was a statistically significant difference in domain scores among the responses to the anchors (p <.001). Based on ROC analysis, SCB was 1.60 for Appearance, 0.87 for Activity, 0.69 for Subtotal, and 0.94 for Total score. Conclusion The results of the current study in an adult spinal deformity population undergoing surgical treatment show SRS22R SCB values of 1.60 for Appearance, 0.87 for Activity, 0.69 for Subtotal, and 0.94 for Total score. These SCB thresholds can be used to quantify the clinical significance of health status change in the surgical management of adult spinal deformity. Level of Evidence Level II. Adult spinal deformity (dpeaa)DE-He213 SRS-22R (dpeaa)DE-He213 Clinical outcomes (dpeaa)DE-He213 Substantial clinical benefit (dpeaa)DE-He213 Glassman, Steven D. aut Bridwell, Keith H. aut Carreon, Leah Y. aut Enthalten in Spine deformity Amsterdam [u.a.] : Elsevier, 2013 4(2016), 5 vom: Sept., Seite 373-377 (DE-627)747142815 (DE-600)2717704-X 2212-1358 nnns volume:4 year:2016 number:5 month:09 pages:373-377 https://dx.doi.org/10.1016/j.jspd.2016.05.001 lizenzpflichtig Volltext GBV_USEFLAG_A SYSFLAG_A GBV_SPRINGER GBV_ILN_647 GBV_ILN_702 GBV_ILN_2004 GBV_ILN_2190 GBV_ILN_2336 AR 4 2016 5 09 373-377 |
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10.1016/j.jspd.2016.05.001 doi (DE-627)SPR038869772 (SPR)j.jspd.2016.05.001-e DE-627 ger DE-627 rakwb eng Crawford, Charles H. verfasserin aut The Substantial Clinical Benefit Threshold for SRS-22R Domains After Surgical Treatment of Adult Spinal Deformity 2016 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier © Scoliosis Research Society 2016 Study Design Longitudinal cohort. Objectives To determine Substantial Clinical Benefit (SCB) thresholds for the SRS22R domains in patients undergoing adult spinal deformity surgery. Summary of Background Data The Scoliosis Research Society 22R (SRS22R) has been shown to be reliable, valid, and responsive to change in adult spinal deformity patients. Although the minimal clinically important difference (MCID) is commonly used to quantify a threshold of improvement, it could be considered a floor value rather than a goal. Methods Patients enrolled in a prospective database of adult spinal deformity undergoing surgery with complete SRS22R preoperation and the SRS30 one-year after surgery were identified. One-year postoperative answers to the last 8 questions of the SRS30 were used as anchors to determine the SCB for the Appearance and Activity domains, Subtotal and Total Score using ROC Curve analysis. Results The sample population consisted of 1,422 patients; 83% were females. Mean age was 53 ± 16 years. Mean preoperative SRS22R Appearance score was 2.50 ± 0.73 improving to 3.62 ± 0.84 at one year postoperative. Mean preoperative SRS22R Activity score was 2.96 ± 0.59 improving to 3.33 ± 0.80 at one year postoperative. Mean preoperative SRS22R Pain score was 2.73 ± 0.92 improving to 3.60 ± 0.93 at one year postoperative. Mean preoperative SRS22R Subtotal was 2.56 ± 0.66 improving to 3.11 ± 0.80 at one year postoperative. There was a statistically significant difference in domain scores among the responses to the anchors (p <.001). Based on ROC analysis, SCB was 1.60 for Appearance, 0.87 for Activity, 0.69 for Subtotal, and 0.94 for Total score. Conclusion The results of the current study in an adult spinal deformity population undergoing surgical treatment show SRS22R SCB values of 1.60 for Appearance, 0.87 for Activity, 0.69 for Subtotal, and 0.94 for Total score. These SCB thresholds can be used to quantify the clinical significance of health status change in the surgical management of adult spinal deformity. Level of Evidence Level II. Adult spinal deformity (dpeaa)DE-He213 SRS-22R (dpeaa)DE-He213 Clinical outcomes (dpeaa)DE-He213 Substantial clinical benefit (dpeaa)DE-He213 Glassman, Steven D. aut Bridwell, Keith H. aut Carreon, Leah Y. aut Enthalten in Spine deformity Amsterdam [u.a.] : Elsevier, 2013 4(2016), 5 vom: Sept., Seite 373-377 (DE-627)747142815 (DE-600)2717704-X 2212-1358 nnns volume:4 year:2016 number:5 month:09 pages:373-377 https://dx.doi.org/10.1016/j.jspd.2016.05.001 lizenzpflichtig Volltext GBV_USEFLAG_A SYSFLAG_A GBV_SPRINGER GBV_ILN_647 GBV_ILN_702 GBV_ILN_2004 GBV_ILN_2190 GBV_ILN_2336 AR 4 2016 5 09 373-377 |
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10.1016/j.jspd.2016.05.001 doi (DE-627)SPR038869772 (SPR)j.jspd.2016.05.001-e DE-627 ger DE-627 rakwb eng Crawford, Charles H. verfasserin aut The Substantial Clinical Benefit Threshold for SRS-22R Domains After Surgical Treatment of Adult Spinal Deformity 2016 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier © Scoliosis Research Society 2016 Study Design Longitudinal cohort. Objectives To determine Substantial Clinical Benefit (SCB) thresholds for the SRS22R domains in patients undergoing adult spinal deformity surgery. Summary of Background Data The Scoliosis Research Society 22R (SRS22R) has been shown to be reliable, valid, and responsive to change in adult spinal deformity patients. Although the minimal clinically important difference (MCID) is commonly used to quantify a threshold of improvement, it could be considered a floor value rather than a goal. Methods Patients enrolled in a prospective database of adult spinal deformity undergoing surgery with complete SRS22R preoperation and the SRS30 one-year after surgery were identified. One-year postoperative answers to the last 8 questions of the SRS30 were used as anchors to determine the SCB for the Appearance and Activity domains, Subtotal and Total Score using ROC Curve analysis. Results The sample population consisted of 1,422 patients; 83% were females. Mean age was 53 ± 16 years. Mean preoperative SRS22R Appearance score was 2.50 ± 0.73 improving to 3.62 ± 0.84 at one year postoperative. Mean preoperative SRS22R Activity score was 2.96 ± 0.59 improving to 3.33 ± 0.80 at one year postoperative. Mean preoperative SRS22R Pain score was 2.73 ± 0.92 improving to 3.60 ± 0.93 at one year postoperative. Mean preoperative SRS22R Subtotal was 2.56 ± 0.66 improving to 3.11 ± 0.80 at one year postoperative. There was a statistically significant difference in domain scores among the responses to the anchors (p <.001). Based on ROC analysis, SCB was 1.60 for Appearance, 0.87 for Activity, 0.69 for Subtotal, and 0.94 for Total score. Conclusion The results of the current study in an adult spinal deformity population undergoing surgical treatment show SRS22R SCB values of 1.60 for Appearance, 0.87 for Activity, 0.69 for Subtotal, and 0.94 for Total score. These SCB thresholds can be used to quantify the clinical significance of health status change in the surgical management of adult spinal deformity. Level of Evidence Level II. Adult spinal deformity (dpeaa)DE-He213 SRS-22R (dpeaa)DE-He213 Clinical outcomes (dpeaa)DE-He213 Substantial clinical benefit (dpeaa)DE-He213 Glassman, Steven D. aut Bridwell, Keith H. aut Carreon, Leah Y. aut Enthalten in Spine deformity Amsterdam [u.a.] : Elsevier, 2013 4(2016), 5 vom: Sept., Seite 373-377 (DE-627)747142815 (DE-600)2717704-X 2212-1358 nnns volume:4 year:2016 number:5 month:09 pages:373-377 https://dx.doi.org/10.1016/j.jspd.2016.05.001 lizenzpflichtig Volltext GBV_USEFLAG_A SYSFLAG_A GBV_SPRINGER GBV_ILN_647 GBV_ILN_702 GBV_ILN_2004 GBV_ILN_2190 GBV_ILN_2336 AR 4 2016 5 09 373-377 |
| allfieldsGer |
10.1016/j.jspd.2016.05.001 doi (DE-627)SPR038869772 (SPR)j.jspd.2016.05.001-e DE-627 ger DE-627 rakwb eng Crawford, Charles H. verfasserin aut The Substantial Clinical Benefit Threshold for SRS-22R Domains After Surgical Treatment of Adult Spinal Deformity 2016 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier © Scoliosis Research Society 2016 Study Design Longitudinal cohort. Objectives To determine Substantial Clinical Benefit (SCB) thresholds for the SRS22R domains in patients undergoing adult spinal deformity surgery. Summary of Background Data The Scoliosis Research Society 22R (SRS22R) has been shown to be reliable, valid, and responsive to change in adult spinal deformity patients. Although the minimal clinically important difference (MCID) is commonly used to quantify a threshold of improvement, it could be considered a floor value rather than a goal. Methods Patients enrolled in a prospective database of adult spinal deformity undergoing surgery with complete SRS22R preoperation and the SRS30 one-year after surgery were identified. One-year postoperative answers to the last 8 questions of the SRS30 were used as anchors to determine the SCB for the Appearance and Activity domains, Subtotal and Total Score using ROC Curve analysis. Results The sample population consisted of 1,422 patients; 83% were females. Mean age was 53 ± 16 years. Mean preoperative SRS22R Appearance score was 2.50 ± 0.73 improving to 3.62 ± 0.84 at one year postoperative. Mean preoperative SRS22R Activity score was 2.96 ± 0.59 improving to 3.33 ± 0.80 at one year postoperative. Mean preoperative SRS22R Pain score was 2.73 ± 0.92 improving to 3.60 ± 0.93 at one year postoperative. Mean preoperative SRS22R Subtotal was 2.56 ± 0.66 improving to 3.11 ± 0.80 at one year postoperative. There was a statistically significant difference in domain scores among the responses to the anchors (p <.001). Based on ROC analysis, SCB was 1.60 for Appearance, 0.87 for Activity, 0.69 for Subtotal, and 0.94 for Total score. Conclusion The results of the current study in an adult spinal deformity population undergoing surgical treatment show SRS22R SCB values of 1.60 for Appearance, 0.87 for Activity, 0.69 for Subtotal, and 0.94 for Total score. These SCB thresholds can be used to quantify the clinical significance of health status change in the surgical management of adult spinal deformity. Level of Evidence Level II. Adult spinal deformity (dpeaa)DE-He213 SRS-22R (dpeaa)DE-He213 Clinical outcomes (dpeaa)DE-He213 Substantial clinical benefit (dpeaa)DE-He213 Glassman, Steven D. aut Bridwell, Keith H. aut Carreon, Leah Y. aut Enthalten in Spine deformity Amsterdam [u.a.] : Elsevier, 2013 4(2016), 5 vom: Sept., Seite 373-377 (DE-627)747142815 (DE-600)2717704-X 2212-1358 nnns volume:4 year:2016 number:5 month:09 pages:373-377 https://dx.doi.org/10.1016/j.jspd.2016.05.001 lizenzpflichtig Volltext GBV_USEFLAG_A SYSFLAG_A GBV_SPRINGER GBV_ILN_647 GBV_ILN_702 GBV_ILN_2004 GBV_ILN_2190 GBV_ILN_2336 AR 4 2016 5 09 373-377 |
| allfieldsSound |
10.1016/j.jspd.2016.05.001 doi (DE-627)SPR038869772 (SPR)j.jspd.2016.05.001-e DE-627 ger DE-627 rakwb eng Crawford, Charles H. verfasserin aut The Substantial Clinical Benefit Threshold for SRS-22R Domains After Surgical Treatment of Adult Spinal Deformity 2016 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier © Scoliosis Research Society 2016 Study Design Longitudinal cohort. Objectives To determine Substantial Clinical Benefit (SCB) thresholds for the SRS22R domains in patients undergoing adult spinal deformity surgery. Summary of Background Data The Scoliosis Research Society 22R (SRS22R) has been shown to be reliable, valid, and responsive to change in adult spinal deformity patients. Although the minimal clinically important difference (MCID) is commonly used to quantify a threshold of improvement, it could be considered a floor value rather than a goal. Methods Patients enrolled in a prospective database of adult spinal deformity undergoing surgery with complete SRS22R preoperation and the SRS30 one-year after surgery were identified. One-year postoperative answers to the last 8 questions of the SRS30 were used as anchors to determine the SCB for the Appearance and Activity domains, Subtotal and Total Score using ROC Curve analysis. Results The sample population consisted of 1,422 patients; 83% were females. Mean age was 53 ± 16 years. Mean preoperative SRS22R Appearance score was 2.50 ± 0.73 improving to 3.62 ± 0.84 at one year postoperative. Mean preoperative SRS22R Activity score was 2.96 ± 0.59 improving to 3.33 ± 0.80 at one year postoperative. Mean preoperative SRS22R Pain score was 2.73 ± 0.92 improving to 3.60 ± 0.93 at one year postoperative. Mean preoperative SRS22R Subtotal was 2.56 ± 0.66 improving to 3.11 ± 0.80 at one year postoperative. There was a statistically significant difference in domain scores among the responses to the anchors (p <.001). Based on ROC analysis, SCB was 1.60 for Appearance, 0.87 for Activity, 0.69 for Subtotal, and 0.94 for Total score. Conclusion The results of the current study in an adult spinal deformity population undergoing surgical treatment show SRS22R SCB values of 1.60 for Appearance, 0.87 for Activity, 0.69 for Subtotal, and 0.94 for Total score. These SCB thresholds can be used to quantify the clinical significance of health status change in the surgical management of adult spinal deformity. Level of Evidence Level II. Adult spinal deformity (dpeaa)DE-He213 SRS-22R (dpeaa)DE-He213 Clinical outcomes (dpeaa)DE-He213 Substantial clinical benefit (dpeaa)DE-He213 Glassman, Steven D. aut Bridwell, Keith H. aut Carreon, Leah Y. aut Enthalten in Spine deformity Amsterdam [u.a.] : Elsevier, 2013 4(2016), 5 vom: Sept., Seite 373-377 (DE-627)747142815 (DE-600)2717704-X 2212-1358 nnns volume:4 year:2016 number:5 month:09 pages:373-377 https://dx.doi.org/10.1016/j.jspd.2016.05.001 lizenzpflichtig Volltext GBV_USEFLAG_A SYSFLAG_A GBV_SPRINGER GBV_ILN_647 GBV_ILN_702 GBV_ILN_2004 GBV_ILN_2190 GBV_ILN_2336 AR 4 2016 5 09 373-377 |
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Objectives To determine Substantial Clinical Benefit (SCB) thresholds for the SRS22R domains in patients undergoing adult spinal deformity surgery. Summary of Background Data The Scoliosis Research Society 22R (SRS22R) has been shown to be reliable, valid, and responsive to change in adult spinal deformity patients. Although the minimal clinically important difference (MCID) is commonly used to quantify a threshold of improvement, it could be considered a floor value rather than a goal. Methods Patients enrolled in a prospective database of adult spinal deformity undergoing surgery with complete SRS22R preoperation and the SRS30 one-year after surgery were identified. One-year postoperative answers to the last 8 questions of the SRS30 were used as anchors to determine the SCB for the Appearance and Activity domains, Subtotal and Total Score using ROC Curve analysis. Results The sample population consisted of 1,422 patients; 83% were females. Mean age was 53 ± 16 years. Mean preoperative SRS22R Appearance score was 2.50 ± 0.73 improving to 3.62 ± 0.84 at one year postoperative. Mean preoperative SRS22R Activity score was 2.96 ± 0.59 improving to 3.33 ± 0.80 at one year postoperative. Mean preoperative SRS22R Pain score was 2.73 ± 0.92 improving to 3.60 ± 0.93 at one year postoperative. Mean preoperative SRS22R Subtotal was 2.56 ± 0.66 improving to 3.11 ± 0.80 at one year postoperative. There was a statistically significant difference in domain scores among the responses to the anchors (p <.001). Based on ROC analysis, SCB was 1.60 for Appearance, 0.87 for Activity, 0.69 for Subtotal, and 0.94 for Total score. Conclusion The results of the current study in an adult spinal deformity population undergoing surgical treatment show SRS22R SCB values of 1.60 for Appearance, 0.87 for Activity, 0.69 for Subtotal, and 0.94 for Total score. These SCB thresholds can be used to quantify the clinical significance of health status change in the surgical management of adult spinal deformity. 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The Substantial Clinical Benefit Threshold for SRS-22R Domains After Surgical Treatment of Adult Spinal Deformity Adult spinal deformity (dpeaa)DE-He213 SRS-22R (dpeaa)DE-He213 Clinical outcomes (dpeaa)DE-He213 Substantial clinical benefit (dpeaa)DE-He213 |
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substantial clinical benefit threshold for srs-22r domains after surgical treatment of adult spinal deformity |
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The Substantial Clinical Benefit Threshold for SRS-22R Domains After Surgical Treatment of Adult Spinal Deformity |
| abstract |
Study Design Longitudinal cohort. Objectives To determine Substantial Clinical Benefit (SCB) thresholds for the SRS22R domains in patients undergoing adult spinal deformity surgery. Summary of Background Data The Scoliosis Research Society 22R (SRS22R) has been shown to be reliable, valid, and responsive to change in adult spinal deformity patients. Although the minimal clinically important difference (MCID) is commonly used to quantify a threshold of improvement, it could be considered a floor value rather than a goal. Methods Patients enrolled in a prospective database of adult spinal deformity undergoing surgery with complete SRS22R preoperation and the SRS30 one-year after surgery were identified. One-year postoperative answers to the last 8 questions of the SRS30 were used as anchors to determine the SCB for the Appearance and Activity domains, Subtotal and Total Score using ROC Curve analysis. Results The sample population consisted of 1,422 patients; 83% were females. Mean age was 53 ± 16 years. Mean preoperative SRS22R Appearance score was 2.50 ± 0.73 improving to 3.62 ± 0.84 at one year postoperative. Mean preoperative SRS22R Activity score was 2.96 ± 0.59 improving to 3.33 ± 0.80 at one year postoperative. Mean preoperative SRS22R Pain score was 2.73 ± 0.92 improving to 3.60 ± 0.93 at one year postoperative. Mean preoperative SRS22R Subtotal was 2.56 ± 0.66 improving to 3.11 ± 0.80 at one year postoperative. There was a statistically significant difference in domain scores among the responses to the anchors (p <.001). Based on ROC analysis, SCB was 1.60 for Appearance, 0.87 for Activity, 0.69 for Subtotal, and 0.94 for Total score. Conclusion The results of the current study in an adult spinal deformity population undergoing surgical treatment show SRS22R SCB values of 1.60 for Appearance, 0.87 for Activity, 0.69 for Subtotal, and 0.94 for Total score. These SCB thresholds can be used to quantify the clinical significance of health status change in the surgical management of adult spinal deformity. Level of Evidence Level II. © Scoliosis Research Society 2016 |
| abstractGer |
Study Design Longitudinal cohort. Objectives To determine Substantial Clinical Benefit (SCB) thresholds for the SRS22R domains in patients undergoing adult spinal deformity surgery. Summary of Background Data The Scoliosis Research Society 22R (SRS22R) has been shown to be reliable, valid, and responsive to change in adult spinal deformity patients. Although the minimal clinically important difference (MCID) is commonly used to quantify a threshold of improvement, it could be considered a floor value rather than a goal. Methods Patients enrolled in a prospective database of adult spinal deformity undergoing surgery with complete SRS22R preoperation and the SRS30 one-year after surgery were identified. One-year postoperative answers to the last 8 questions of the SRS30 were used as anchors to determine the SCB for the Appearance and Activity domains, Subtotal and Total Score using ROC Curve analysis. Results The sample population consisted of 1,422 patients; 83% were females. Mean age was 53 ± 16 years. Mean preoperative SRS22R Appearance score was 2.50 ± 0.73 improving to 3.62 ± 0.84 at one year postoperative. Mean preoperative SRS22R Activity score was 2.96 ± 0.59 improving to 3.33 ± 0.80 at one year postoperative. Mean preoperative SRS22R Pain score was 2.73 ± 0.92 improving to 3.60 ± 0.93 at one year postoperative. Mean preoperative SRS22R Subtotal was 2.56 ± 0.66 improving to 3.11 ± 0.80 at one year postoperative. There was a statistically significant difference in domain scores among the responses to the anchors (p <.001). Based on ROC analysis, SCB was 1.60 for Appearance, 0.87 for Activity, 0.69 for Subtotal, and 0.94 for Total score. Conclusion The results of the current study in an adult spinal deformity population undergoing surgical treatment show SRS22R SCB values of 1.60 for Appearance, 0.87 for Activity, 0.69 for Subtotal, and 0.94 for Total score. These SCB thresholds can be used to quantify the clinical significance of health status change in the surgical management of adult spinal deformity. Level of Evidence Level II. © Scoliosis Research Society 2016 |
| abstract_unstemmed |
Study Design Longitudinal cohort. Objectives To determine Substantial Clinical Benefit (SCB) thresholds for the SRS22R domains in patients undergoing adult spinal deformity surgery. Summary of Background Data The Scoliosis Research Society 22R (SRS22R) has been shown to be reliable, valid, and responsive to change in adult spinal deformity patients. Although the minimal clinically important difference (MCID) is commonly used to quantify a threshold of improvement, it could be considered a floor value rather than a goal. Methods Patients enrolled in a prospective database of adult spinal deformity undergoing surgery with complete SRS22R preoperation and the SRS30 one-year after surgery were identified. One-year postoperative answers to the last 8 questions of the SRS30 were used as anchors to determine the SCB for the Appearance and Activity domains, Subtotal and Total Score using ROC Curve analysis. Results The sample population consisted of 1,422 patients; 83% were females. Mean age was 53 ± 16 years. Mean preoperative SRS22R Appearance score was 2.50 ± 0.73 improving to 3.62 ± 0.84 at one year postoperative. Mean preoperative SRS22R Activity score was 2.96 ± 0.59 improving to 3.33 ± 0.80 at one year postoperative. Mean preoperative SRS22R Pain score was 2.73 ± 0.92 improving to 3.60 ± 0.93 at one year postoperative. Mean preoperative SRS22R Subtotal was 2.56 ± 0.66 improving to 3.11 ± 0.80 at one year postoperative. There was a statistically significant difference in domain scores among the responses to the anchors (p <.001). Based on ROC analysis, SCB was 1.60 for Appearance, 0.87 for Activity, 0.69 for Subtotal, and 0.94 for Total score. Conclusion The results of the current study in an adult spinal deformity population undergoing surgical treatment show SRS22R SCB values of 1.60 for Appearance, 0.87 for Activity, 0.69 for Subtotal, and 0.94 for Total score. These SCB thresholds can be used to quantify the clinical significance of health status change in the surgical management of adult spinal deformity. Level of Evidence Level II. © Scoliosis Research Society 2016 |
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