Impedance testing of porous $ Si_{3} %$ N_{4} $ scaffolds for skeletal implant applications
Abstract $ Si_{3} %$ N_{4} $ ceramics show excellent characteristics of mechanical and chemical resistance in combination with good biocompatibility, antibacterial property and radiolucency. Therefore, they are intensively studied as structural materials in skeletal implant applications. Despite the...
Ausführliche Beschreibung
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| Autor*in: |
Akbulut, Serdar Onat [verfasserIn] Ghorbanpoor, Hamed [verfasserIn] İpteç, Betül Özbek [verfasserIn] Butterworth, Adrian [verfasserIn] Avcıoğlu, Gamze [verfasserIn] Kozacı, Leyla Didem [verfasserIn] Topateş, Gülsüm [verfasserIn] Corrigan, Damion K. [verfasserIn] Avcı, Hüseyin [verfasserIn] Güzel, Fatma D. [verfasserIn] |
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| Format: |
E-Artikel |
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| Sprache: |
Englisch |
| Erschienen: |
2020 |
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| Schlagwörter: |
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| Übergeordnetes Werk: |
Enthalten in: SN applied sciences - [Cham] : Springer International Publishing, 2019, 2(2020), 5 vom: 06. Apr. |
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| Übergeordnetes Werk: |
volume:2 ; year:2020 ; number:5 ; day:06 ; month:04 |
| Links: |
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| DOI / URN: |
10.1007/s42452-020-2624-4 |
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| Katalog-ID: |
SPR039331776 |
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| 520 | |a Abstract $ Si_{3} %$ N_{4} $ ceramics show excellent characteristics of mechanical and chemical resistance in combination with good biocompatibility, antibacterial property and radiolucency. Therefore, they are intensively studied as structural materials in skeletal implant applications. Despite their attractive properties, there are limited data in the field about in vitro studies of cellular growth on ceramic implant materials. In this study, the growth of bone cells was investigated on porous silicon nitride ($ Si_{3} %$ N_{4} $) ceramic implant by using electrochemical impedance spectroscopy (EIS). Partial sintering was performed at 1700 °C with limited amount of sintering additive for the production of porous $ Si_{3} %$ N_{4} $ scaffolds. All samples were then sterilized by using ethylene oxide followed by culturing MG-63 osteosarcoma cells on the substrates for in vitro assays. At 20 and 36 h, EIS was performed and results demonstrated that magnitude of the impedance as a result of the changes in the culture medium increased after incubation with osteosarcoma cells. The changes are attributed to the cellular uptake of charged molecules from the medium. $ Si_{3} %$ N_{4} $ samples appear to show large impedance magnitude changes, especially between 100 and 1 Hz. Impedance changes were also correlated with WST-1 measurements (36 h) and DAPI results. | ||
| 650 | 4 | |a Electrochemical impedance spectroscopy |7 (dpeaa)DE-He213 | |
| 650 | 4 | |a Cellular attachment |7 (dpeaa)DE-He213 | |
| 650 | 4 | |a Bone implant |7 (dpeaa)DE-He213 | |
| 650 | 4 | |a Si |7 (dpeaa)DE-He213 | |
| 650 | 4 | |a N |7 (dpeaa)DE-He213 | |
| 700 | 1 | |a Ghorbanpoor, Hamed |e verfasserin |4 aut | |
| 700 | 1 | |a İpteç, Betül Özbek |e verfasserin |4 aut | |
| 700 | 1 | |a Butterworth, Adrian |e verfasserin |4 aut | |
| 700 | 1 | |a Avcıoğlu, Gamze |e verfasserin |4 aut | |
| 700 | 1 | |a Kozacı, Leyla Didem |e verfasserin |4 aut | |
| 700 | 1 | |a Topateş, Gülsüm |e verfasserin |4 aut | |
| 700 | 1 | |a Corrigan, Damion K. |e verfasserin |4 aut | |
| 700 | 1 | |a Avcı, Hüseyin |e verfasserin |4 aut | |
| 700 | 1 | |a Güzel, Fatma D. |e verfasserin |4 aut | |
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10.1007/s42452-020-2624-4 doi (DE-627)SPR039331776 (SPR)s42452-020-2624-4-e DE-627 ger DE-627 rakwb eng 500 ASE 500 ASE 50.00 bkl 35.00 bkl 33.00 bkl Akbulut, Serdar Onat verfasserin aut Impedance testing of porous $ Si_{3} %$ N_{4} $ scaffolds for skeletal implant applications 2020 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Abstract $ Si_{3} %$ N_{4} $ ceramics show excellent characteristics of mechanical and chemical resistance in combination with good biocompatibility, antibacterial property and radiolucency. Therefore, they are intensively studied as structural materials in skeletal implant applications. Despite their attractive properties, there are limited data in the field about in vitro studies of cellular growth on ceramic implant materials. In this study, the growth of bone cells was investigated on porous silicon nitride ($ Si_{3} %$ N_{4} $) ceramic implant by using electrochemical impedance spectroscopy (EIS). Partial sintering was performed at 1700 °C with limited amount of sintering additive for the production of porous $ Si_{3} %$ N_{4} $ scaffolds. All samples were then sterilized by using ethylene oxide followed by culturing MG-63 osteosarcoma cells on the substrates for in vitro assays. At 20 and 36 h, EIS was performed and results demonstrated that magnitude of the impedance as a result of the changes in the culture medium increased after incubation with osteosarcoma cells. The changes are attributed to the cellular uptake of charged molecules from the medium. $ Si_{3} %$ N_{4} $ samples appear to show large impedance magnitude changes, especially between 100 and 1 Hz. Impedance changes were also correlated with WST-1 measurements (36 h) and DAPI results. Electrochemical impedance spectroscopy (dpeaa)DE-He213 Cellular attachment (dpeaa)DE-He213 Bone implant (dpeaa)DE-He213 Si (dpeaa)DE-He213 N (dpeaa)DE-He213 Ghorbanpoor, Hamed verfasserin aut İpteç, Betül Özbek verfasserin aut Butterworth, Adrian verfasserin aut Avcıoğlu, Gamze verfasserin aut Kozacı, Leyla Didem verfasserin aut Topateş, Gülsüm verfasserin aut Corrigan, Damion K. verfasserin aut Avcı, Hüseyin verfasserin aut Güzel, Fatma D. verfasserin aut Enthalten in SN applied sciences [Cham] : Springer International Publishing, 2019 2(2020), 5 vom: 06. Apr. (DE-627)103761139X (DE-600)2947292-1 2523-3971 nnns volume:2 year:2020 number:5 day:06 month:04 https://dx.doi.org/10.1007/s42452-020-2624-4 kostenfrei Volltext GBV_USEFLAG_A SYSFLAG_A GBV_SPRINGER GBV_ILN_11 GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_32 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_70 GBV_ILN_73 GBV_ILN_90 GBV_ILN_95 GBV_ILN_100 GBV_ILN_105 GBV_ILN_110 GBV_ILN_138 GBV_ILN_151 GBV_ILN_152 GBV_ILN_161 GBV_ILN_170 GBV_ILN_171 GBV_ILN_187 GBV_ILN_213 GBV_ILN_224 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_370 GBV_ILN_602 GBV_ILN_636 GBV_ILN_702 GBV_ILN_2001 GBV_ILN_2003 GBV_ILN_2004 GBV_ILN_2005 GBV_ILN_2006 GBV_ILN_2007 GBV_ILN_2009 GBV_ILN_2010 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2015 GBV_ILN_2020 GBV_ILN_2021 GBV_ILN_2025 GBV_ILN_2026 GBV_ILN_2027 GBV_ILN_2031 GBV_ILN_2034 GBV_ILN_2037 GBV_ILN_2038 GBV_ILN_2039 GBV_ILN_2044 GBV_ILN_2048 GBV_ILN_2049 GBV_ILN_2050 GBV_ILN_2055 GBV_ILN_2056 GBV_ILN_2057 GBV_ILN_2059 GBV_ILN_2061 GBV_ILN_2064 GBV_ILN_2065 GBV_ILN_2068 GBV_ILN_2088 GBV_ILN_2093 GBV_ILN_2106 GBV_ILN_2107 GBV_ILN_2108 GBV_ILN_2110 GBV_ILN_2111 GBV_ILN_2112 GBV_ILN_2113 GBV_ILN_2118 GBV_ILN_2122 GBV_ILN_2129 GBV_ILN_2143 GBV_ILN_2144 GBV_ILN_2147 GBV_ILN_2148 GBV_ILN_2152 GBV_ILN_2153 GBV_ILN_2190 GBV_ILN_2232 GBV_ILN_2336 GBV_ILN_2470 GBV_ILN_2472 GBV_ILN_2507 GBV_ILN_2522 GBV_ILN_4012 GBV_ILN_4035 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4242 GBV_ILN_4246 GBV_ILN_4249 GBV_ILN_4251 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4326 GBV_ILN_4328 GBV_ILN_4333 GBV_ILN_4334 GBV_ILN_4335 GBV_ILN_4336 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4393 GBV_ILN_4700 50.00 ASE 35.00 ASE 33.00 ASE AR 2 2020 5 06 04 |
| spelling |
10.1007/s42452-020-2624-4 doi (DE-627)SPR039331776 (SPR)s42452-020-2624-4-e DE-627 ger DE-627 rakwb eng 500 ASE 500 ASE 50.00 bkl 35.00 bkl 33.00 bkl Akbulut, Serdar Onat verfasserin aut Impedance testing of porous $ Si_{3} %$ N_{4} $ scaffolds for skeletal implant applications 2020 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Abstract $ Si_{3} %$ N_{4} $ ceramics show excellent characteristics of mechanical and chemical resistance in combination with good biocompatibility, antibacterial property and radiolucency. Therefore, they are intensively studied as structural materials in skeletal implant applications. Despite their attractive properties, there are limited data in the field about in vitro studies of cellular growth on ceramic implant materials. In this study, the growth of bone cells was investigated on porous silicon nitride ($ Si_{3} %$ N_{4} $) ceramic implant by using electrochemical impedance spectroscopy (EIS). Partial sintering was performed at 1700 °C with limited amount of sintering additive for the production of porous $ Si_{3} %$ N_{4} $ scaffolds. All samples were then sterilized by using ethylene oxide followed by culturing MG-63 osteosarcoma cells on the substrates for in vitro assays. At 20 and 36 h, EIS was performed and results demonstrated that magnitude of the impedance as a result of the changes in the culture medium increased after incubation with osteosarcoma cells. The changes are attributed to the cellular uptake of charged molecules from the medium. $ Si_{3} %$ N_{4} $ samples appear to show large impedance magnitude changes, especially between 100 and 1 Hz. Impedance changes were also correlated with WST-1 measurements (36 h) and DAPI results. Electrochemical impedance spectroscopy (dpeaa)DE-He213 Cellular attachment (dpeaa)DE-He213 Bone implant (dpeaa)DE-He213 Si (dpeaa)DE-He213 N (dpeaa)DE-He213 Ghorbanpoor, Hamed verfasserin aut İpteç, Betül Özbek verfasserin aut Butterworth, Adrian verfasserin aut Avcıoğlu, Gamze verfasserin aut Kozacı, Leyla Didem verfasserin aut Topateş, Gülsüm verfasserin aut Corrigan, Damion K. verfasserin aut Avcı, Hüseyin verfasserin aut Güzel, Fatma D. verfasserin aut Enthalten in SN applied sciences [Cham] : Springer International Publishing, 2019 2(2020), 5 vom: 06. Apr. (DE-627)103761139X (DE-600)2947292-1 2523-3971 nnns volume:2 year:2020 number:5 day:06 month:04 https://dx.doi.org/10.1007/s42452-020-2624-4 kostenfrei Volltext GBV_USEFLAG_A SYSFLAG_A GBV_SPRINGER GBV_ILN_11 GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_32 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_70 GBV_ILN_73 GBV_ILN_90 GBV_ILN_95 GBV_ILN_100 GBV_ILN_105 GBV_ILN_110 GBV_ILN_138 GBV_ILN_151 GBV_ILN_152 GBV_ILN_161 GBV_ILN_170 GBV_ILN_171 GBV_ILN_187 GBV_ILN_213 GBV_ILN_224 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_370 GBV_ILN_602 GBV_ILN_636 GBV_ILN_702 GBV_ILN_2001 GBV_ILN_2003 GBV_ILN_2004 GBV_ILN_2005 GBV_ILN_2006 GBV_ILN_2007 GBV_ILN_2009 GBV_ILN_2010 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2015 GBV_ILN_2020 GBV_ILN_2021 GBV_ILN_2025 GBV_ILN_2026 GBV_ILN_2027 GBV_ILN_2031 GBV_ILN_2034 GBV_ILN_2037 GBV_ILN_2038 GBV_ILN_2039 GBV_ILN_2044 GBV_ILN_2048 GBV_ILN_2049 GBV_ILN_2050 GBV_ILN_2055 GBV_ILN_2056 GBV_ILN_2057 GBV_ILN_2059 GBV_ILN_2061 GBV_ILN_2064 GBV_ILN_2065 GBV_ILN_2068 GBV_ILN_2088 GBV_ILN_2093 GBV_ILN_2106 GBV_ILN_2107 GBV_ILN_2108 GBV_ILN_2110 GBV_ILN_2111 GBV_ILN_2112 GBV_ILN_2113 GBV_ILN_2118 GBV_ILN_2122 GBV_ILN_2129 GBV_ILN_2143 GBV_ILN_2144 GBV_ILN_2147 GBV_ILN_2148 GBV_ILN_2152 GBV_ILN_2153 GBV_ILN_2190 GBV_ILN_2232 GBV_ILN_2336 GBV_ILN_2470 GBV_ILN_2472 GBV_ILN_2507 GBV_ILN_2522 GBV_ILN_4012 GBV_ILN_4035 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4242 GBV_ILN_4246 GBV_ILN_4249 GBV_ILN_4251 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4326 GBV_ILN_4328 GBV_ILN_4333 GBV_ILN_4334 GBV_ILN_4335 GBV_ILN_4336 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4393 GBV_ILN_4700 50.00 ASE 35.00 ASE 33.00 ASE AR 2 2020 5 06 04 |
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10.1007/s42452-020-2624-4 doi (DE-627)SPR039331776 (SPR)s42452-020-2624-4-e DE-627 ger DE-627 rakwb eng 500 ASE 500 ASE 50.00 bkl 35.00 bkl 33.00 bkl Akbulut, Serdar Onat verfasserin aut Impedance testing of porous $ Si_{3} %$ N_{4} $ scaffolds for skeletal implant applications 2020 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Abstract $ Si_{3} %$ N_{4} $ ceramics show excellent characteristics of mechanical and chemical resistance in combination with good biocompatibility, antibacterial property and radiolucency. Therefore, they are intensively studied as structural materials in skeletal implant applications. Despite their attractive properties, there are limited data in the field about in vitro studies of cellular growth on ceramic implant materials. In this study, the growth of bone cells was investigated on porous silicon nitride ($ Si_{3} %$ N_{4} $) ceramic implant by using electrochemical impedance spectroscopy (EIS). Partial sintering was performed at 1700 °C with limited amount of sintering additive for the production of porous $ Si_{3} %$ N_{4} $ scaffolds. All samples were then sterilized by using ethylene oxide followed by culturing MG-63 osteosarcoma cells on the substrates for in vitro assays. At 20 and 36 h, EIS was performed and results demonstrated that magnitude of the impedance as a result of the changes in the culture medium increased after incubation with osteosarcoma cells. The changes are attributed to the cellular uptake of charged molecules from the medium. $ Si_{3} %$ N_{4} $ samples appear to show large impedance magnitude changes, especially between 100 and 1 Hz. Impedance changes were also correlated with WST-1 measurements (36 h) and DAPI results. Electrochemical impedance spectroscopy (dpeaa)DE-He213 Cellular attachment (dpeaa)DE-He213 Bone implant (dpeaa)DE-He213 Si (dpeaa)DE-He213 N (dpeaa)DE-He213 Ghorbanpoor, Hamed verfasserin aut İpteç, Betül Özbek verfasserin aut Butterworth, Adrian verfasserin aut Avcıoğlu, Gamze verfasserin aut Kozacı, Leyla Didem verfasserin aut Topateş, Gülsüm verfasserin aut Corrigan, Damion K. verfasserin aut Avcı, Hüseyin verfasserin aut Güzel, Fatma D. verfasserin aut Enthalten in SN applied sciences [Cham] : Springer International Publishing, 2019 2(2020), 5 vom: 06. Apr. (DE-627)103761139X (DE-600)2947292-1 2523-3971 nnns volume:2 year:2020 number:5 day:06 month:04 https://dx.doi.org/10.1007/s42452-020-2624-4 kostenfrei Volltext GBV_USEFLAG_A SYSFLAG_A GBV_SPRINGER GBV_ILN_11 GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_32 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_70 GBV_ILN_73 GBV_ILN_90 GBV_ILN_95 GBV_ILN_100 GBV_ILN_105 GBV_ILN_110 GBV_ILN_138 GBV_ILN_151 GBV_ILN_152 GBV_ILN_161 GBV_ILN_170 GBV_ILN_171 GBV_ILN_187 GBV_ILN_213 GBV_ILN_224 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_370 GBV_ILN_602 GBV_ILN_636 GBV_ILN_702 GBV_ILN_2001 GBV_ILN_2003 GBV_ILN_2004 GBV_ILN_2005 GBV_ILN_2006 GBV_ILN_2007 GBV_ILN_2009 GBV_ILN_2010 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2015 GBV_ILN_2020 GBV_ILN_2021 GBV_ILN_2025 GBV_ILN_2026 GBV_ILN_2027 GBV_ILN_2031 GBV_ILN_2034 GBV_ILN_2037 GBV_ILN_2038 GBV_ILN_2039 GBV_ILN_2044 GBV_ILN_2048 GBV_ILN_2049 GBV_ILN_2050 GBV_ILN_2055 GBV_ILN_2056 GBV_ILN_2057 GBV_ILN_2059 GBV_ILN_2061 GBV_ILN_2064 GBV_ILN_2065 GBV_ILN_2068 GBV_ILN_2088 GBV_ILN_2093 GBV_ILN_2106 GBV_ILN_2107 GBV_ILN_2108 GBV_ILN_2110 GBV_ILN_2111 GBV_ILN_2112 GBV_ILN_2113 GBV_ILN_2118 GBV_ILN_2122 GBV_ILN_2129 GBV_ILN_2143 GBV_ILN_2144 GBV_ILN_2147 GBV_ILN_2148 GBV_ILN_2152 GBV_ILN_2153 GBV_ILN_2190 GBV_ILN_2232 GBV_ILN_2336 GBV_ILN_2470 GBV_ILN_2472 GBV_ILN_2507 GBV_ILN_2522 GBV_ILN_4012 GBV_ILN_4035 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4242 GBV_ILN_4246 GBV_ILN_4249 GBV_ILN_4251 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4326 GBV_ILN_4328 GBV_ILN_4333 GBV_ILN_4334 GBV_ILN_4335 GBV_ILN_4336 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4393 GBV_ILN_4700 50.00 ASE 35.00 ASE 33.00 ASE AR 2 2020 5 06 04 |
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10.1007/s42452-020-2624-4 doi (DE-627)SPR039331776 (SPR)s42452-020-2624-4-e DE-627 ger DE-627 rakwb eng 500 ASE 500 ASE 50.00 bkl 35.00 bkl 33.00 bkl Akbulut, Serdar Onat verfasserin aut Impedance testing of porous $ Si_{3} %$ N_{4} $ scaffolds for skeletal implant applications 2020 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Abstract $ Si_{3} %$ N_{4} $ ceramics show excellent characteristics of mechanical and chemical resistance in combination with good biocompatibility, antibacterial property and radiolucency. Therefore, they are intensively studied as structural materials in skeletal implant applications. Despite their attractive properties, there are limited data in the field about in vitro studies of cellular growth on ceramic implant materials. In this study, the growth of bone cells was investigated on porous silicon nitride ($ Si_{3} %$ N_{4} $) ceramic implant by using electrochemical impedance spectroscopy (EIS). Partial sintering was performed at 1700 °C with limited amount of sintering additive for the production of porous $ Si_{3} %$ N_{4} $ scaffolds. All samples were then sterilized by using ethylene oxide followed by culturing MG-63 osteosarcoma cells on the substrates for in vitro assays. At 20 and 36 h, EIS was performed and results demonstrated that magnitude of the impedance as a result of the changes in the culture medium increased after incubation with osteosarcoma cells. The changes are attributed to the cellular uptake of charged molecules from the medium. $ Si_{3} %$ N_{4} $ samples appear to show large impedance magnitude changes, especially between 100 and 1 Hz. Impedance changes were also correlated with WST-1 measurements (36 h) and DAPI results. Electrochemical impedance spectroscopy (dpeaa)DE-He213 Cellular attachment (dpeaa)DE-He213 Bone implant (dpeaa)DE-He213 Si (dpeaa)DE-He213 N (dpeaa)DE-He213 Ghorbanpoor, Hamed verfasserin aut İpteç, Betül Özbek verfasserin aut Butterworth, Adrian verfasserin aut Avcıoğlu, Gamze verfasserin aut Kozacı, Leyla Didem verfasserin aut Topateş, Gülsüm verfasserin aut Corrigan, Damion K. verfasserin aut Avcı, Hüseyin verfasserin aut Güzel, Fatma D. verfasserin aut Enthalten in SN applied sciences [Cham] : Springer International Publishing, 2019 2(2020), 5 vom: 06. Apr. (DE-627)103761139X (DE-600)2947292-1 2523-3971 nnns volume:2 year:2020 number:5 day:06 month:04 https://dx.doi.org/10.1007/s42452-020-2624-4 kostenfrei Volltext GBV_USEFLAG_A SYSFLAG_A GBV_SPRINGER GBV_ILN_11 GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_32 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_70 GBV_ILN_73 GBV_ILN_90 GBV_ILN_95 GBV_ILN_100 GBV_ILN_105 GBV_ILN_110 GBV_ILN_138 GBV_ILN_151 GBV_ILN_152 GBV_ILN_161 GBV_ILN_170 GBV_ILN_171 GBV_ILN_187 GBV_ILN_213 GBV_ILN_224 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_370 GBV_ILN_602 GBV_ILN_636 GBV_ILN_702 GBV_ILN_2001 GBV_ILN_2003 GBV_ILN_2004 GBV_ILN_2005 GBV_ILN_2006 GBV_ILN_2007 GBV_ILN_2009 GBV_ILN_2010 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2015 GBV_ILN_2020 GBV_ILN_2021 GBV_ILN_2025 GBV_ILN_2026 GBV_ILN_2027 GBV_ILN_2031 GBV_ILN_2034 GBV_ILN_2037 GBV_ILN_2038 GBV_ILN_2039 GBV_ILN_2044 GBV_ILN_2048 GBV_ILN_2049 GBV_ILN_2050 GBV_ILN_2055 GBV_ILN_2056 GBV_ILN_2057 GBV_ILN_2059 GBV_ILN_2061 GBV_ILN_2064 GBV_ILN_2065 GBV_ILN_2068 GBV_ILN_2088 GBV_ILN_2093 GBV_ILN_2106 GBV_ILN_2107 GBV_ILN_2108 GBV_ILN_2110 GBV_ILN_2111 GBV_ILN_2112 GBV_ILN_2113 GBV_ILN_2118 GBV_ILN_2122 GBV_ILN_2129 GBV_ILN_2143 GBV_ILN_2144 GBV_ILN_2147 GBV_ILN_2148 GBV_ILN_2152 GBV_ILN_2153 GBV_ILN_2190 GBV_ILN_2232 GBV_ILN_2336 GBV_ILN_2470 GBV_ILN_2472 GBV_ILN_2507 GBV_ILN_2522 GBV_ILN_4012 GBV_ILN_4035 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4242 GBV_ILN_4246 GBV_ILN_4249 GBV_ILN_4251 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4326 GBV_ILN_4328 GBV_ILN_4333 GBV_ILN_4334 GBV_ILN_4335 GBV_ILN_4336 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4393 GBV_ILN_4700 50.00 ASE 35.00 ASE 33.00 ASE AR 2 2020 5 06 04 |
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10.1007/s42452-020-2624-4 doi (DE-627)SPR039331776 (SPR)s42452-020-2624-4-e DE-627 ger DE-627 rakwb eng 500 ASE 500 ASE 50.00 bkl 35.00 bkl 33.00 bkl Akbulut, Serdar Onat verfasserin aut Impedance testing of porous $ Si_{3} %$ N_{4} $ scaffolds for skeletal implant applications 2020 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Abstract $ Si_{3} %$ N_{4} $ ceramics show excellent characteristics of mechanical and chemical resistance in combination with good biocompatibility, antibacterial property and radiolucency. Therefore, they are intensively studied as structural materials in skeletal implant applications. Despite their attractive properties, there are limited data in the field about in vitro studies of cellular growth on ceramic implant materials. In this study, the growth of bone cells was investigated on porous silicon nitride ($ Si_{3} %$ N_{4} $) ceramic implant by using electrochemical impedance spectroscopy (EIS). Partial sintering was performed at 1700 °C with limited amount of sintering additive for the production of porous $ Si_{3} %$ N_{4} $ scaffolds. All samples were then sterilized by using ethylene oxide followed by culturing MG-63 osteosarcoma cells on the substrates for in vitro assays. At 20 and 36 h, EIS was performed and results demonstrated that magnitude of the impedance as a result of the changes in the culture medium increased after incubation with osteosarcoma cells. The changes are attributed to the cellular uptake of charged molecules from the medium. $ Si_{3} %$ N_{4} $ samples appear to show large impedance magnitude changes, especially between 100 and 1 Hz. Impedance changes were also correlated with WST-1 measurements (36 h) and DAPI results. Electrochemical impedance spectroscopy (dpeaa)DE-He213 Cellular attachment (dpeaa)DE-He213 Bone implant (dpeaa)DE-He213 Si (dpeaa)DE-He213 N (dpeaa)DE-He213 Ghorbanpoor, Hamed verfasserin aut İpteç, Betül Özbek verfasserin aut Butterworth, Adrian verfasserin aut Avcıoğlu, Gamze verfasserin aut Kozacı, Leyla Didem verfasserin aut Topateş, Gülsüm verfasserin aut Corrigan, Damion K. verfasserin aut Avcı, Hüseyin verfasserin aut Güzel, Fatma D. verfasserin aut Enthalten in SN applied sciences [Cham] : Springer International Publishing, 2019 2(2020), 5 vom: 06. Apr. (DE-627)103761139X (DE-600)2947292-1 2523-3971 nnns volume:2 year:2020 number:5 day:06 month:04 https://dx.doi.org/10.1007/s42452-020-2624-4 kostenfrei Volltext GBV_USEFLAG_A SYSFLAG_A GBV_SPRINGER GBV_ILN_11 GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_32 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_70 GBV_ILN_73 GBV_ILN_90 GBV_ILN_95 GBV_ILN_100 GBV_ILN_105 GBV_ILN_110 GBV_ILN_138 GBV_ILN_151 GBV_ILN_152 GBV_ILN_161 GBV_ILN_170 GBV_ILN_171 GBV_ILN_187 GBV_ILN_213 GBV_ILN_224 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_370 GBV_ILN_602 GBV_ILN_636 GBV_ILN_702 GBV_ILN_2001 GBV_ILN_2003 GBV_ILN_2004 GBV_ILN_2005 GBV_ILN_2006 GBV_ILN_2007 GBV_ILN_2009 GBV_ILN_2010 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2015 GBV_ILN_2020 GBV_ILN_2021 GBV_ILN_2025 GBV_ILN_2026 GBV_ILN_2027 GBV_ILN_2031 GBV_ILN_2034 GBV_ILN_2037 GBV_ILN_2038 GBV_ILN_2039 GBV_ILN_2044 GBV_ILN_2048 GBV_ILN_2049 GBV_ILN_2050 GBV_ILN_2055 GBV_ILN_2056 GBV_ILN_2057 GBV_ILN_2059 GBV_ILN_2061 GBV_ILN_2064 GBV_ILN_2065 GBV_ILN_2068 GBV_ILN_2088 GBV_ILN_2093 GBV_ILN_2106 GBV_ILN_2107 GBV_ILN_2108 GBV_ILN_2110 GBV_ILN_2111 GBV_ILN_2112 GBV_ILN_2113 GBV_ILN_2118 GBV_ILN_2122 GBV_ILN_2129 GBV_ILN_2143 GBV_ILN_2144 GBV_ILN_2147 GBV_ILN_2148 GBV_ILN_2152 GBV_ILN_2153 GBV_ILN_2190 GBV_ILN_2232 GBV_ILN_2336 GBV_ILN_2470 GBV_ILN_2472 GBV_ILN_2507 GBV_ILN_2522 GBV_ILN_4012 GBV_ILN_4035 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4242 GBV_ILN_4246 GBV_ILN_4249 GBV_ILN_4251 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4326 GBV_ILN_4328 GBV_ILN_4333 GBV_ILN_4334 GBV_ILN_4335 GBV_ILN_4336 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4393 GBV_ILN_4700 50.00 ASE 35.00 ASE 33.00 ASE AR 2 2020 5 06 04 |
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Enthalten in SN applied sciences 2(2020), 5 vom: 06. Apr. volume:2 year:2020 number:5 day:06 month:04 |
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Enthalten in SN applied sciences 2(2020), 5 vom: 06. Apr. volume:2 year:2020 number:5 day:06 month:04 |
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Electrochemical impedance spectroscopy Cellular attachment Bone implant Si N |
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Akbulut, Serdar Onat @@aut@@ Ghorbanpoor, Hamed @@aut@@ İpteç, Betül Özbek @@aut@@ Butterworth, Adrian @@aut@@ Avcıoğlu, Gamze @@aut@@ Kozacı, Leyla Didem @@aut@@ Topateş, Gülsüm @@aut@@ Corrigan, Damion K. @@aut@@ Avcı, Hüseyin @@aut@@ Güzel, Fatma D. @@aut@@ |
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Therefore, they are intensively studied as structural materials in skeletal implant applications. Despite their attractive properties, there are limited data in the field about in vitro studies of cellular growth on ceramic implant materials. In this study, the growth of bone cells was investigated on porous silicon nitride ($ Si_{3} %$ N_{4} $) ceramic implant by using electrochemical impedance spectroscopy (EIS). Partial sintering was performed at 1700 °C with limited amount of sintering additive for the production of porous $ Si_{3} %$ N_{4} $ scaffolds. All samples were then sterilized by using ethylene oxide followed by culturing MG-63 osteosarcoma cells on the substrates for in vitro assays. At 20 and 36 h, EIS was performed and results demonstrated that magnitude of the impedance as a result of the changes in the culture medium increased after incubation with osteosarcoma cells. The changes are attributed to the cellular uptake of charged molecules from the medium. $ Si_{3} %$ N_{4} $ samples appear to show large impedance magnitude changes, especially between 100 and 1 Hz. 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Akbulut, Serdar Onat |
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Akbulut, Serdar Onat ddc 500 bkl 50.00 bkl 35.00 bkl 33.00 misc Electrochemical impedance spectroscopy misc Cellular attachment misc Bone implant misc Si misc N Impedance testing of porous $ Si_{3} %$ N_{4} $ scaffolds for skeletal implant applications |
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500 ASE 50.00 bkl 35.00 bkl 33.00 bkl Impedance testing of porous $ Si_{3} %$ N_{4} $ scaffolds for skeletal implant applications Electrochemical impedance spectroscopy (dpeaa)DE-He213 Cellular attachment (dpeaa)DE-He213 Bone implant (dpeaa)DE-He213 Si (dpeaa)DE-He213 N (dpeaa)DE-He213 |
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Akbulut, Serdar Onat Ghorbanpoor, Hamed İpteç, Betül Özbek Butterworth, Adrian Avcıoğlu, Gamze Kozacı, Leyla Didem Topateş, Gülsüm Corrigan, Damion K. Avcı, Hüseyin Güzel, Fatma D. |
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impedance testing of porous $ si_{3} %$ n_{4} $ scaffolds for skeletal implant applications |
| title_auth |
Impedance testing of porous $ Si_{3} %$ N_{4} $ scaffolds for skeletal implant applications |
| abstract |
Abstract $ Si_{3} %$ N_{4} $ ceramics show excellent characteristics of mechanical and chemical resistance in combination with good biocompatibility, antibacterial property and radiolucency. Therefore, they are intensively studied as structural materials in skeletal implant applications. Despite their attractive properties, there are limited data in the field about in vitro studies of cellular growth on ceramic implant materials. In this study, the growth of bone cells was investigated on porous silicon nitride ($ Si_{3} %$ N_{4} $) ceramic implant by using electrochemical impedance spectroscopy (EIS). Partial sintering was performed at 1700 °C with limited amount of sintering additive for the production of porous $ Si_{3} %$ N_{4} $ scaffolds. All samples were then sterilized by using ethylene oxide followed by culturing MG-63 osteosarcoma cells on the substrates for in vitro assays. At 20 and 36 h, EIS was performed and results demonstrated that magnitude of the impedance as a result of the changes in the culture medium increased after incubation with osteosarcoma cells. The changes are attributed to the cellular uptake of charged molecules from the medium. $ Si_{3} %$ N_{4} $ samples appear to show large impedance magnitude changes, especially between 100 and 1 Hz. Impedance changes were also correlated with WST-1 measurements (36 h) and DAPI results. |
| abstractGer |
Abstract $ Si_{3} %$ N_{4} $ ceramics show excellent characteristics of mechanical and chemical resistance in combination with good biocompatibility, antibacterial property and radiolucency. Therefore, they are intensively studied as structural materials in skeletal implant applications. Despite their attractive properties, there are limited data in the field about in vitro studies of cellular growth on ceramic implant materials. In this study, the growth of bone cells was investigated on porous silicon nitride ($ Si_{3} %$ N_{4} $) ceramic implant by using electrochemical impedance spectroscopy (EIS). Partial sintering was performed at 1700 °C with limited amount of sintering additive for the production of porous $ Si_{3} %$ N_{4} $ scaffolds. All samples were then sterilized by using ethylene oxide followed by culturing MG-63 osteosarcoma cells on the substrates for in vitro assays. At 20 and 36 h, EIS was performed and results demonstrated that magnitude of the impedance as a result of the changes in the culture medium increased after incubation with osteosarcoma cells. The changes are attributed to the cellular uptake of charged molecules from the medium. $ Si_{3} %$ N_{4} $ samples appear to show large impedance magnitude changes, especially between 100 and 1 Hz. Impedance changes were also correlated with WST-1 measurements (36 h) and DAPI results. |
| abstract_unstemmed |
Abstract $ Si_{3} %$ N_{4} $ ceramics show excellent characteristics of mechanical and chemical resistance in combination with good biocompatibility, antibacterial property and radiolucency. Therefore, they are intensively studied as structural materials in skeletal implant applications. Despite their attractive properties, there are limited data in the field about in vitro studies of cellular growth on ceramic implant materials. In this study, the growth of bone cells was investigated on porous silicon nitride ($ Si_{3} %$ N_{4} $) ceramic implant by using electrochemical impedance spectroscopy (EIS). Partial sintering was performed at 1700 °C with limited amount of sintering additive for the production of porous $ Si_{3} %$ N_{4} $ scaffolds. All samples were then sterilized by using ethylene oxide followed by culturing MG-63 osteosarcoma cells on the substrates for in vitro assays. At 20 and 36 h, EIS was performed and results demonstrated that magnitude of the impedance as a result of the changes in the culture medium increased after incubation with osteosarcoma cells. The changes are attributed to the cellular uptake of charged molecules from the medium. $ Si_{3} %$ N_{4} $ samples appear to show large impedance magnitude changes, especially between 100 and 1 Hz. Impedance changes were also correlated with WST-1 measurements (36 h) and DAPI results. |
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| title_short |
Impedance testing of porous $ Si_{3} %$ N_{4} $ scaffolds for skeletal implant applications |
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https://dx.doi.org/10.1007/s42452-020-2624-4 |
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Ghorbanpoor, Hamed İpteç, Betül Özbek Butterworth, Adrian Avcıoğlu, Gamze Kozacı, Leyla Didem Topateş, Gülsüm Corrigan, Damion K. Avcı, Hüseyin Güzel, Fatma D. |
| author2Str |
Ghorbanpoor, Hamed İpteç, Betül Özbek Butterworth, Adrian Avcıoğlu, Gamze Kozacı, Leyla Didem Topateş, Gülsüm Corrigan, Damion K. Avcı, Hüseyin Güzel, Fatma D. |
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10.1007/s42452-020-2624-4 |
| up_date |
2024-07-03T23:22:23.245Z |
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| score |
7.401886 |