An “all-wheel drive” proposal to accelerate clinical research in common and rare neurological diseases
Abstract The complex biology of neurological diseases calls for collaborative efforts that may increase the success rate of clinical research. Models have been proposed, but concrete actions remain insufficient. Based on recent considerations from basic science, from science of patient input and fro...
Ausführliche Beschreibung
Gespeichert in:
| Autor*in: |
Salvetti, Marco [verfasserIn] Battaglia, Mario A. [verfasserIn] Di Filippo, Massimiliano [verfasserIn] Mancardi, Gian Luigi [verfasserIn] Mancuso, Michelangelo [verfasserIn] Patti, Francesco [verfasserIn] Sormani, Maria Pia [verfasserIn] Zaratin, Paola [verfasserIn] |
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| Format: |
E-Artikel |
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| Sprache: |
Englisch |
| Erschienen: |
2019 |
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| Schlagwörter: |
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| Übergeordnetes Werk: |
Enthalten in: Neurological sciences - Milano : Springer, 2000, 41(2019), 4 vom: 19. Dez., Seite 789-793 |
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| Übergeordnetes Werk: |
volume:41 ; year:2019 ; number:4 ; day:19 ; month:12 ; pages:789-793 |
| Links: |
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| DOI / URN: |
10.1007/s10072-019-04189-4 |
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| Katalog-ID: |
SPR039407829 |
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| 245 | 1 | 3 | |a An “all-wheel drive” proposal to accelerate clinical research in common and rare neurological diseases |
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| 520 | |a Abstract The complex biology of neurological diseases calls for collaborative efforts that may increase the success rate of clinical research. Models have been proposed, but concrete actions remain insufficient. Based on recent considerations from basic science, from science of patient input and from an analysis of scientific resources in Italy, we here explain why our country may represent an appropriate environment for such actions. Furthermore, we sketch operational framework and business model to be applied in order to accelerate, in parallel, the development of therapies in common and rare diseases. | ||
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| 650 | 4 | |a Rare diseases |7 (dpeaa)DE-He213 | |
| 650 | 4 | |a Pathophysiology |7 (dpeaa)DE-He213 | |
| 650 | 4 | |a Clinical research |7 (dpeaa)DE-He213 | |
| 650 | 4 | |a Therapies |7 (dpeaa)DE-He213 | |
| 700 | 1 | |a Battaglia, Mario A. |e verfasserin |4 aut | |
| 700 | 1 | |a Di Filippo, Massimiliano |e verfasserin |4 aut | |
| 700 | 1 | |a Mancardi, Gian Luigi |e verfasserin |4 aut | |
| 700 | 1 | |a Mancuso, Michelangelo |e verfasserin |4 aut | |
| 700 | 1 | |a Patti, Francesco |e verfasserin |4 aut | |
| 700 | 1 | |a Sormani, Maria Pia |e verfasserin |4 aut | |
| 700 | 1 | |a Zaratin, Paola |e verfasserin |4 aut | |
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10.1007/s10072-019-04189-4 doi (DE-627)SPR039407829 (SPR)s10072-019-04189-4-e DE-627 ger DE-627 rakwb eng 610 ASE 610 ASE 44.90 bkl Salvetti, Marco verfasserin aut An “all-wheel drive” proposal to accelerate clinical research in common and rare neurological diseases 2019 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Abstract The complex biology of neurological diseases calls for collaborative efforts that may increase the success rate of clinical research. Models have been proposed, but concrete actions remain insufficient. Based on recent considerations from basic science, from science of patient input and from an analysis of scientific resources in Italy, we here explain why our country may represent an appropriate environment for such actions. Furthermore, we sketch operational framework and business model to be applied in order to accelerate, in parallel, the development of therapies in common and rare diseases. Multiple sclerosis (dpeaa)DE-He213 Rare diseases (dpeaa)DE-He213 Pathophysiology (dpeaa)DE-He213 Clinical research (dpeaa)DE-He213 Therapies (dpeaa)DE-He213 Battaglia, Mario A. verfasserin aut Di Filippo, Massimiliano verfasserin aut Mancardi, Gian Luigi verfasserin aut Mancuso, Michelangelo verfasserin aut Patti, Francesco verfasserin aut Sormani, Maria Pia verfasserin aut Zaratin, Paola verfasserin aut Enthalten in Neurological sciences Milano : Springer, 2000 41(2019), 4 vom: 19. Dez., Seite 789-793 (DE-627)300187025 (DE-600)1481772-X 1590-3478 nnns volume:41 year:2019 number:4 day:19 month:12 pages:789-793 https://dx.doi.org/10.1007/s10072-019-04189-4 kostenfrei Volltext GBV_USEFLAG_A SYSFLAG_A GBV_SPRINGER SSG-OLC-PHA GBV_ILN_11 GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_32 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_70 GBV_ILN_73 GBV_ILN_74 GBV_ILN_90 GBV_ILN_95 GBV_ILN_100 GBV_ILN_101 GBV_ILN_105 GBV_ILN_110 GBV_ILN_120 GBV_ILN_138 GBV_ILN_150 GBV_ILN_151 GBV_ILN_152 GBV_ILN_161 GBV_ILN_170 GBV_ILN_171 GBV_ILN_187 GBV_ILN_206 GBV_ILN_213 GBV_ILN_224 GBV_ILN_230 GBV_ILN_250 GBV_ILN_281 GBV_ILN_285 GBV_ILN_293 GBV_ILN_370 GBV_ILN_602 GBV_ILN_636 GBV_ILN_702 GBV_ILN_711 GBV_ILN_2001 GBV_ILN_2003 GBV_ILN_2004 GBV_ILN_2005 GBV_ILN_2006 GBV_ILN_2007 GBV_ILN_2008 GBV_ILN_2009 GBV_ILN_2010 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2015 GBV_ILN_2020 GBV_ILN_2021 GBV_ILN_2025 GBV_ILN_2026 GBV_ILN_2027 GBV_ILN_2031 GBV_ILN_2034 GBV_ILN_2037 GBV_ILN_2038 GBV_ILN_2039 GBV_ILN_2044 GBV_ILN_2048 GBV_ILN_2049 GBV_ILN_2050 GBV_ILN_2055 GBV_ILN_2056 GBV_ILN_2057 GBV_ILN_2059 GBV_ILN_2061 GBV_ILN_2064 GBV_ILN_2065 GBV_ILN_2068 GBV_ILN_2070 GBV_ILN_2086 GBV_ILN_2088 GBV_ILN_2093 GBV_ILN_2106 GBV_ILN_2107 GBV_ILN_2108 GBV_ILN_2110 GBV_ILN_2111 GBV_ILN_2112 GBV_ILN_2113 GBV_ILN_2116 GBV_ILN_2118 GBV_ILN_2119 GBV_ILN_2122 GBV_ILN_2129 GBV_ILN_2143 GBV_ILN_2144 GBV_ILN_2147 GBV_ILN_2148 GBV_ILN_2152 GBV_ILN_2153 GBV_ILN_2188 GBV_ILN_2190 GBV_ILN_2232 GBV_ILN_2336 GBV_ILN_2446 GBV_ILN_2470 GBV_ILN_2507 GBV_ILN_2522 GBV_ILN_2548 GBV_ILN_4035 GBV_ILN_4037 GBV_ILN_4046 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4242 GBV_ILN_4246 GBV_ILN_4249 GBV_ILN_4251 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4326 GBV_ILN_4333 GBV_ILN_4334 GBV_ILN_4335 GBV_ILN_4336 GBV_ILN_4338 GBV_ILN_4393 GBV_ILN_4700 44.90 ASE AR 41 2019 4 19 12 789-793 |
| spelling |
10.1007/s10072-019-04189-4 doi (DE-627)SPR039407829 (SPR)s10072-019-04189-4-e DE-627 ger DE-627 rakwb eng 610 ASE 610 ASE 44.90 bkl Salvetti, Marco verfasserin aut An “all-wheel drive” proposal to accelerate clinical research in common and rare neurological diseases 2019 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Abstract The complex biology of neurological diseases calls for collaborative efforts that may increase the success rate of clinical research. Models have been proposed, but concrete actions remain insufficient. Based on recent considerations from basic science, from science of patient input and from an analysis of scientific resources in Italy, we here explain why our country may represent an appropriate environment for such actions. Furthermore, we sketch operational framework and business model to be applied in order to accelerate, in parallel, the development of therapies in common and rare diseases. Multiple sclerosis (dpeaa)DE-He213 Rare diseases (dpeaa)DE-He213 Pathophysiology (dpeaa)DE-He213 Clinical research (dpeaa)DE-He213 Therapies (dpeaa)DE-He213 Battaglia, Mario A. verfasserin aut Di Filippo, Massimiliano verfasserin aut Mancardi, Gian Luigi verfasserin aut Mancuso, Michelangelo verfasserin aut Patti, Francesco verfasserin aut Sormani, Maria Pia verfasserin aut Zaratin, Paola verfasserin aut Enthalten in Neurological sciences Milano : Springer, 2000 41(2019), 4 vom: 19. Dez., Seite 789-793 (DE-627)300187025 (DE-600)1481772-X 1590-3478 nnns volume:41 year:2019 number:4 day:19 month:12 pages:789-793 https://dx.doi.org/10.1007/s10072-019-04189-4 kostenfrei Volltext GBV_USEFLAG_A SYSFLAG_A GBV_SPRINGER SSG-OLC-PHA GBV_ILN_11 GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_32 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_70 GBV_ILN_73 GBV_ILN_74 GBV_ILN_90 GBV_ILN_95 GBV_ILN_100 GBV_ILN_101 GBV_ILN_105 GBV_ILN_110 GBV_ILN_120 GBV_ILN_138 GBV_ILN_150 GBV_ILN_151 GBV_ILN_152 GBV_ILN_161 GBV_ILN_170 GBV_ILN_171 GBV_ILN_187 GBV_ILN_206 GBV_ILN_213 GBV_ILN_224 GBV_ILN_230 GBV_ILN_250 GBV_ILN_281 GBV_ILN_285 GBV_ILN_293 GBV_ILN_370 GBV_ILN_602 GBV_ILN_636 GBV_ILN_702 GBV_ILN_711 GBV_ILN_2001 GBV_ILN_2003 GBV_ILN_2004 GBV_ILN_2005 GBV_ILN_2006 GBV_ILN_2007 GBV_ILN_2008 GBV_ILN_2009 GBV_ILN_2010 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2015 GBV_ILN_2020 GBV_ILN_2021 GBV_ILN_2025 GBV_ILN_2026 GBV_ILN_2027 GBV_ILN_2031 GBV_ILN_2034 GBV_ILN_2037 GBV_ILN_2038 GBV_ILN_2039 GBV_ILN_2044 GBV_ILN_2048 GBV_ILN_2049 GBV_ILN_2050 GBV_ILN_2055 GBV_ILN_2056 GBV_ILN_2057 GBV_ILN_2059 GBV_ILN_2061 GBV_ILN_2064 GBV_ILN_2065 GBV_ILN_2068 GBV_ILN_2070 GBV_ILN_2086 GBV_ILN_2088 GBV_ILN_2093 GBV_ILN_2106 GBV_ILN_2107 GBV_ILN_2108 GBV_ILN_2110 GBV_ILN_2111 GBV_ILN_2112 GBV_ILN_2113 GBV_ILN_2116 GBV_ILN_2118 GBV_ILN_2119 GBV_ILN_2122 GBV_ILN_2129 GBV_ILN_2143 GBV_ILN_2144 GBV_ILN_2147 GBV_ILN_2148 GBV_ILN_2152 GBV_ILN_2153 GBV_ILN_2188 GBV_ILN_2190 GBV_ILN_2232 GBV_ILN_2336 GBV_ILN_2446 GBV_ILN_2470 GBV_ILN_2507 GBV_ILN_2522 GBV_ILN_2548 GBV_ILN_4035 GBV_ILN_4037 GBV_ILN_4046 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4242 GBV_ILN_4246 GBV_ILN_4249 GBV_ILN_4251 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4326 GBV_ILN_4333 GBV_ILN_4334 GBV_ILN_4335 GBV_ILN_4336 GBV_ILN_4338 GBV_ILN_4393 GBV_ILN_4700 44.90 ASE AR 41 2019 4 19 12 789-793 |
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10.1007/s10072-019-04189-4 doi (DE-627)SPR039407829 (SPR)s10072-019-04189-4-e DE-627 ger DE-627 rakwb eng 610 ASE 610 ASE 44.90 bkl Salvetti, Marco verfasserin aut An “all-wheel drive” proposal to accelerate clinical research in common and rare neurological diseases 2019 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Abstract The complex biology of neurological diseases calls for collaborative efforts that may increase the success rate of clinical research. Models have been proposed, but concrete actions remain insufficient. Based on recent considerations from basic science, from science of patient input and from an analysis of scientific resources in Italy, we here explain why our country may represent an appropriate environment for such actions. Furthermore, we sketch operational framework and business model to be applied in order to accelerate, in parallel, the development of therapies in common and rare diseases. Multiple sclerosis (dpeaa)DE-He213 Rare diseases (dpeaa)DE-He213 Pathophysiology (dpeaa)DE-He213 Clinical research (dpeaa)DE-He213 Therapies (dpeaa)DE-He213 Battaglia, Mario A. verfasserin aut Di Filippo, Massimiliano verfasserin aut Mancardi, Gian Luigi verfasserin aut Mancuso, Michelangelo verfasserin aut Patti, Francesco verfasserin aut Sormani, Maria Pia verfasserin aut Zaratin, Paola verfasserin aut Enthalten in Neurological sciences Milano : Springer, 2000 41(2019), 4 vom: 19. Dez., Seite 789-793 (DE-627)300187025 (DE-600)1481772-X 1590-3478 nnns volume:41 year:2019 number:4 day:19 month:12 pages:789-793 https://dx.doi.org/10.1007/s10072-019-04189-4 kostenfrei Volltext GBV_USEFLAG_A SYSFLAG_A GBV_SPRINGER SSG-OLC-PHA GBV_ILN_11 GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_32 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_70 GBV_ILN_73 GBV_ILN_74 GBV_ILN_90 GBV_ILN_95 GBV_ILN_100 GBV_ILN_101 GBV_ILN_105 GBV_ILN_110 GBV_ILN_120 GBV_ILN_138 GBV_ILN_150 GBV_ILN_151 GBV_ILN_152 GBV_ILN_161 GBV_ILN_170 GBV_ILN_171 GBV_ILN_187 GBV_ILN_206 GBV_ILN_213 GBV_ILN_224 GBV_ILN_230 GBV_ILN_250 GBV_ILN_281 GBV_ILN_285 GBV_ILN_293 GBV_ILN_370 GBV_ILN_602 GBV_ILN_636 GBV_ILN_702 GBV_ILN_711 GBV_ILN_2001 GBV_ILN_2003 GBV_ILN_2004 GBV_ILN_2005 GBV_ILN_2006 GBV_ILN_2007 GBV_ILN_2008 GBV_ILN_2009 GBV_ILN_2010 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2015 GBV_ILN_2020 GBV_ILN_2021 GBV_ILN_2025 GBV_ILN_2026 GBV_ILN_2027 GBV_ILN_2031 GBV_ILN_2034 GBV_ILN_2037 GBV_ILN_2038 GBV_ILN_2039 GBV_ILN_2044 GBV_ILN_2048 GBV_ILN_2049 GBV_ILN_2050 GBV_ILN_2055 GBV_ILN_2056 GBV_ILN_2057 GBV_ILN_2059 GBV_ILN_2061 GBV_ILN_2064 GBV_ILN_2065 GBV_ILN_2068 GBV_ILN_2070 GBV_ILN_2086 GBV_ILN_2088 GBV_ILN_2093 GBV_ILN_2106 GBV_ILN_2107 GBV_ILN_2108 GBV_ILN_2110 GBV_ILN_2111 GBV_ILN_2112 GBV_ILN_2113 GBV_ILN_2116 GBV_ILN_2118 GBV_ILN_2119 GBV_ILN_2122 GBV_ILN_2129 GBV_ILN_2143 GBV_ILN_2144 GBV_ILN_2147 GBV_ILN_2148 GBV_ILN_2152 GBV_ILN_2153 GBV_ILN_2188 GBV_ILN_2190 GBV_ILN_2232 GBV_ILN_2336 GBV_ILN_2446 GBV_ILN_2470 GBV_ILN_2507 GBV_ILN_2522 GBV_ILN_2548 GBV_ILN_4035 GBV_ILN_4037 GBV_ILN_4046 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4242 GBV_ILN_4246 GBV_ILN_4249 GBV_ILN_4251 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4326 GBV_ILN_4333 GBV_ILN_4334 GBV_ILN_4335 GBV_ILN_4336 GBV_ILN_4338 GBV_ILN_4393 GBV_ILN_4700 44.90 ASE AR 41 2019 4 19 12 789-793 |
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10.1007/s10072-019-04189-4 doi (DE-627)SPR039407829 (SPR)s10072-019-04189-4-e DE-627 ger DE-627 rakwb eng 610 ASE 610 ASE 44.90 bkl Salvetti, Marco verfasserin aut An “all-wheel drive” proposal to accelerate clinical research in common and rare neurological diseases 2019 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Abstract The complex biology of neurological diseases calls for collaborative efforts that may increase the success rate of clinical research. Models have been proposed, but concrete actions remain insufficient. Based on recent considerations from basic science, from science of patient input and from an analysis of scientific resources in Italy, we here explain why our country may represent an appropriate environment for such actions. Furthermore, we sketch operational framework and business model to be applied in order to accelerate, in parallel, the development of therapies in common and rare diseases. Multiple sclerosis (dpeaa)DE-He213 Rare diseases (dpeaa)DE-He213 Pathophysiology (dpeaa)DE-He213 Clinical research (dpeaa)DE-He213 Therapies (dpeaa)DE-He213 Battaglia, Mario A. verfasserin aut Di Filippo, Massimiliano verfasserin aut Mancardi, Gian Luigi verfasserin aut Mancuso, Michelangelo verfasserin aut Patti, Francesco verfasserin aut Sormani, Maria Pia verfasserin aut Zaratin, Paola verfasserin aut Enthalten in Neurological sciences Milano : Springer, 2000 41(2019), 4 vom: 19. Dez., Seite 789-793 (DE-627)300187025 (DE-600)1481772-X 1590-3478 nnns volume:41 year:2019 number:4 day:19 month:12 pages:789-793 https://dx.doi.org/10.1007/s10072-019-04189-4 kostenfrei Volltext GBV_USEFLAG_A SYSFLAG_A GBV_SPRINGER SSG-OLC-PHA GBV_ILN_11 GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_32 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_70 GBV_ILN_73 GBV_ILN_74 GBV_ILN_90 GBV_ILN_95 GBV_ILN_100 GBV_ILN_101 GBV_ILN_105 GBV_ILN_110 GBV_ILN_120 GBV_ILN_138 GBV_ILN_150 GBV_ILN_151 GBV_ILN_152 GBV_ILN_161 GBV_ILN_170 GBV_ILN_171 GBV_ILN_187 GBV_ILN_206 GBV_ILN_213 GBV_ILN_224 GBV_ILN_230 GBV_ILN_250 GBV_ILN_281 GBV_ILN_285 GBV_ILN_293 GBV_ILN_370 GBV_ILN_602 GBV_ILN_636 GBV_ILN_702 GBV_ILN_711 GBV_ILN_2001 GBV_ILN_2003 GBV_ILN_2004 GBV_ILN_2005 GBV_ILN_2006 GBV_ILN_2007 GBV_ILN_2008 GBV_ILN_2009 GBV_ILN_2010 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2015 GBV_ILN_2020 GBV_ILN_2021 GBV_ILN_2025 GBV_ILN_2026 GBV_ILN_2027 GBV_ILN_2031 GBV_ILN_2034 GBV_ILN_2037 GBV_ILN_2038 GBV_ILN_2039 GBV_ILN_2044 GBV_ILN_2048 GBV_ILN_2049 GBV_ILN_2050 GBV_ILN_2055 GBV_ILN_2056 GBV_ILN_2057 GBV_ILN_2059 GBV_ILN_2061 GBV_ILN_2064 GBV_ILN_2065 GBV_ILN_2068 GBV_ILN_2070 GBV_ILN_2086 GBV_ILN_2088 GBV_ILN_2093 GBV_ILN_2106 GBV_ILN_2107 GBV_ILN_2108 GBV_ILN_2110 GBV_ILN_2111 GBV_ILN_2112 GBV_ILN_2113 GBV_ILN_2116 GBV_ILN_2118 GBV_ILN_2119 GBV_ILN_2122 GBV_ILN_2129 GBV_ILN_2143 GBV_ILN_2144 GBV_ILN_2147 GBV_ILN_2148 GBV_ILN_2152 GBV_ILN_2153 GBV_ILN_2188 GBV_ILN_2190 GBV_ILN_2232 GBV_ILN_2336 GBV_ILN_2446 GBV_ILN_2470 GBV_ILN_2507 GBV_ILN_2522 GBV_ILN_2548 GBV_ILN_4035 GBV_ILN_4037 GBV_ILN_4046 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4242 GBV_ILN_4246 GBV_ILN_4249 GBV_ILN_4251 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4326 GBV_ILN_4333 GBV_ILN_4334 GBV_ILN_4335 GBV_ILN_4336 GBV_ILN_4338 GBV_ILN_4393 GBV_ILN_4700 44.90 ASE AR 41 2019 4 19 12 789-793 |
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10.1007/s10072-019-04189-4 doi (DE-627)SPR039407829 (SPR)s10072-019-04189-4-e DE-627 ger DE-627 rakwb eng 610 ASE 610 ASE 44.90 bkl Salvetti, Marco verfasserin aut An “all-wheel drive” proposal to accelerate clinical research in common and rare neurological diseases 2019 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Abstract The complex biology of neurological diseases calls for collaborative efforts that may increase the success rate of clinical research. Models have been proposed, but concrete actions remain insufficient. Based on recent considerations from basic science, from science of patient input and from an analysis of scientific resources in Italy, we here explain why our country may represent an appropriate environment for such actions. Furthermore, we sketch operational framework and business model to be applied in order to accelerate, in parallel, the development of therapies in common and rare diseases. Multiple sclerosis (dpeaa)DE-He213 Rare diseases (dpeaa)DE-He213 Pathophysiology (dpeaa)DE-He213 Clinical research (dpeaa)DE-He213 Therapies (dpeaa)DE-He213 Battaglia, Mario A. verfasserin aut Di Filippo, Massimiliano verfasserin aut Mancardi, Gian Luigi verfasserin aut Mancuso, Michelangelo verfasserin aut Patti, Francesco verfasserin aut Sormani, Maria Pia verfasserin aut Zaratin, Paola verfasserin aut Enthalten in Neurological sciences Milano : Springer, 2000 41(2019), 4 vom: 19. Dez., Seite 789-793 (DE-627)300187025 (DE-600)1481772-X 1590-3478 nnns volume:41 year:2019 number:4 day:19 month:12 pages:789-793 https://dx.doi.org/10.1007/s10072-019-04189-4 kostenfrei Volltext GBV_USEFLAG_A SYSFLAG_A GBV_SPRINGER SSG-OLC-PHA GBV_ILN_11 GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_32 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_70 GBV_ILN_73 GBV_ILN_74 GBV_ILN_90 GBV_ILN_95 GBV_ILN_100 GBV_ILN_101 GBV_ILN_105 GBV_ILN_110 GBV_ILN_120 GBV_ILN_138 GBV_ILN_150 GBV_ILN_151 GBV_ILN_152 GBV_ILN_161 GBV_ILN_170 GBV_ILN_171 GBV_ILN_187 GBV_ILN_206 GBV_ILN_213 GBV_ILN_224 GBV_ILN_230 GBV_ILN_250 GBV_ILN_281 GBV_ILN_285 GBV_ILN_293 GBV_ILN_370 GBV_ILN_602 GBV_ILN_636 GBV_ILN_702 GBV_ILN_711 GBV_ILN_2001 GBV_ILN_2003 GBV_ILN_2004 GBV_ILN_2005 GBV_ILN_2006 GBV_ILN_2007 GBV_ILN_2008 GBV_ILN_2009 GBV_ILN_2010 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2015 GBV_ILN_2020 GBV_ILN_2021 GBV_ILN_2025 GBV_ILN_2026 GBV_ILN_2027 GBV_ILN_2031 GBV_ILN_2034 GBV_ILN_2037 GBV_ILN_2038 GBV_ILN_2039 GBV_ILN_2044 GBV_ILN_2048 GBV_ILN_2049 GBV_ILN_2050 GBV_ILN_2055 GBV_ILN_2056 GBV_ILN_2057 GBV_ILN_2059 GBV_ILN_2061 GBV_ILN_2064 GBV_ILN_2065 GBV_ILN_2068 GBV_ILN_2070 GBV_ILN_2086 GBV_ILN_2088 GBV_ILN_2093 GBV_ILN_2106 GBV_ILN_2107 GBV_ILN_2108 GBV_ILN_2110 GBV_ILN_2111 GBV_ILN_2112 GBV_ILN_2113 GBV_ILN_2116 GBV_ILN_2118 GBV_ILN_2119 GBV_ILN_2122 GBV_ILN_2129 GBV_ILN_2143 GBV_ILN_2144 GBV_ILN_2147 GBV_ILN_2148 GBV_ILN_2152 GBV_ILN_2153 GBV_ILN_2188 GBV_ILN_2190 GBV_ILN_2232 GBV_ILN_2336 GBV_ILN_2446 GBV_ILN_2470 GBV_ILN_2507 GBV_ILN_2522 GBV_ILN_2548 GBV_ILN_4035 GBV_ILN_4037 GBV_ILN_4046 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4242 GBV_ILN_4246 GBV_ILN_4249 GBV_ILN_4251 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4326 GBV_ILN_4333 GBV_ILN_4334 GBV_ILN_4335 GBV_ILN_4336 GBV_ILN_4338 GBV_ILN_4393 GBV_ILN_4700 44.90 ASE AR 41 2019 4 19 12 789-793 |
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English |
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Enthalten in Neurological sciences 41(2019), 4 vom: 19. Dez., Seite 789-793 volume:41 year:2019 number:4 day:19 month:12 pages:789-793 |
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Enthalten in Neurological sciences 41(2019), 4 vom: 19. Dez., Seite 789-793 volume:41 year:2019 number:4 day:19 month:12 pages:789-793 |
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Multiple sclerosis Rare diseases Pathophysiology Clinical research Therapies |
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Neurological sciences |
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Salvetti, Marco @@aut@@ Battaglia, Mario A. @@aut@@ Di Filippo, Massimiliano @@aut@@ Mancardi, Gian Luigi @@aut@@ Mancuso, Michelangelo @@aut@@ Patti, Francesco @@aut@@ Sormani, Maria Pia @@aut@@ Zaratin, Paola @@aut@@ |
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2019-12-19T00:00:00Z |
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3610 |
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SPR039407829 |
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Salvetti, Marco |
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Salvetti, Marco ddc 610 bkl 44.90 misc Multiple sclerosis misc Rare diseases misc Pathophysiology misc Clinical research misc Therapies An “all-wheel drive” proposal to accelerate clinical research in common and rare neurological diseases |
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610 ASE 44.90 bkl An “all-wheel drive” proposal to accelerate clinical research in common and rare neurological diseases Multiple sclerosis (dpeaa)DE-He213 Rare diseases (dpeaa)DE-He213 Pathophysiology (dpeaa)DE-He213 Clinical research (dpeaa)DE-He213 Therapies (dpeaa)DE-He213 |
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Salvetti, Marco Battaglia, Mario A. Di Filippo, Massimiliano Mancardi, Gian Luigi Mancuso, Michelangelo Patti, Francesco Sormani, Maria Pia Zaratin, Paola |
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“all-wheel drive” proposal to accelerate clinical research in common and rare neurological diseases |
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An “all-wheel drive” proposal to accelerate clinical research in common and rare neurological diseases |
| abstract |
Abstract The complex biology of neurological diseases calls for collaborative efforts that may increase the success rate of clinical research. Models have been proposed, but concrete actions remain insufficient. Based on recent considerations from basic science, from science of patient input and from an analysis of scientific resources in Italy, we here explain why our country may represent an appropriate environment for such actions. Furthermore, we sketch operational framework and business model to be applied in order to accelerate, in parallel, the development of therapies in common and rare diseases. |
| abstractGer |
Abstract The complex biology of neurological diseases calls for collaborative efforts that may increase the success rate of clinical research. Models have been proposed, but concrete actions remain insufficient. Based on recent considerations from basic science, from science of patient input and from an analysis of scientific resources in Italy, we here explain why our country may represent an appropriate environment for such actions. Furthermore, we sketch operational framework and business model to be applied in order to accelerate, in parallel, the development of therapies in common and rare diseases. |
| abstract_unstemmed |
Abstract The complex biology of neurological diseases calls for collaborative efforts that may increase the success rate of clinical research. Models have been proposed, but concrete actions remain insufficient. Based on recent considerations from basic science, from science of patient input and from an analysis of scientific resources in Italy, we here explain why our country may represent an appropriate environment for such actions. Furthermore, we sketch operational framework and business model to be applied in order to accelerate, in parallel, the development of therapies in common and rare diseases. |
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| container_issue |
4 |
| title_short |
An “all-wheel drive” proposal to accelerate clinical research in common and rare neurological diseases |
| url |
https://dx.doi.org/10.1007/s10072-019-04189-4 |
| remote_bool |
true |
| author2 |
Battaglia, Mario A. Di Filippo, Massimiliano Mancardi, Gian Luigi Mancuso, Michelangelo Patti, Francesco Sormani, Maria Pia Zaratin, Paola |
| author2Str |
Battaglia, Mario A. Di Filippo, Massimiliano Mancardi, Gian Luigi Mancuso, Michelangelo Patti, Francesco Sormani, Maria Pia Zaratin, Paola |
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| doi_str |
10.1007/s10072-019-04189-4 |
| up_date |
2024-07-03T23:47:15.475Z |
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| score |
7.400509 |