Does treatment method matter? A meta-analysis of the past 20 years of research on therapeutic interventions for self-harm and suicidal ideation in adolescents
Background Self-harm is a clinically relevant and prevalent behaviour which peaks in adolescence. Given the high prevalence of self-harm, the high levels of psychiatric comorbidity, and its role as a risk factor for suicide, delivering evidence-based care is critical. Methods We conducted a systemat...
Ausführliche Beschreibung
Autor*in: |
Kothgassner, Oswald D. [verfasserIn] Robinson, Kealagh [verfasserIn] Goreis, Andreas [verfasserIn] Ougrin, Dennis [verfasserIn] Plener, Paul L. [verfasserIn] |
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E-Artikel |
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Sprache: |
Englisch |
Erschienen: |
2020 |
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Übergeordnetes Werk: |
Enthalten in: Borderline Personality Disorder and Emotion Dysregulation - London : BioMed Central, 2014, 7(2020), 1 vom: 11. Mai |
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Übergeordnetes Werk: |
volume:7 ; year:2020 ; number:1 ; day:11 ; month:05 |
Links: |
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DOI / URN: |
10.1186/s40479-020-00123-9 |
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Katalog-ID: |
SPR039674185 |
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520 | |a Background Self-harm is a clinically relevant and prevalent behaviour which peaks in adolescence. Given the high prevalence of self-harm, the high levels of psychiatric comorbidity, and its role as a risk factor for suicide, delivering evidence-based care is critical. Methods We conducted a systematic review and meta-analysis of the literature on treating self-harm in adolescents (12–19 years) published in the last 20 years, identifying 25 randomised controlled trials. We calculated the effect of treatment interventions relative to active control conditions in reducing self-harm, suicidal ideation and depressive symptoms. Results Overall, treatment interventions fared slightly better than active controls in decreasing self-harm (d = 0.13, 95% CI 0.04–0.22, p = .004), suicidal ideation (d = 0.31, 95% CI 0.12–0.50, p = .001) and depressive symptoms (d = 0.22, 95% CI 0.07–0.38, p = .006). Subgroup analysis of specific therapies revealed moderate effects of DBT-A in reducing self-harm (d = 0.51, 95% CI 0.18–0.85, p = .002) and suicidal ideation (d = 0.48, 95% CI 0.17–0.80, p = .003), as well as moderate effects of family-centred therapy in the treating suicidal ideation (d = 0.58, 95% CI 0.01–1.15, p = .049). Conclusions The findings of our meta-analysis indicate that, overall, currently available treatments are effective in treating self-harm, suicidal ideation, and depressive symptoms in adolescence. Although the treatment intervention conditions showed only small to moderate effects in comparison to active controls, these differences were statistically significant and are clinically important. Further research is needed to understand the reduction in self-harm within active controls, which may arise due to the natural course of self-harm, or the potential efficacy of treatment as usual and enhanced usual care. Given the significant reduction of self-harm in active control conditions, delivering effective care to a large number of adolescents with self-harm may require developing stepped-care models in clinical practice. Expensive and poorly available treatments should be targeted at young people who most need them. | ||
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700 | 1 | |a Plener, Paul L. |e verfasserin |4 aut | |
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10.1186/s40479-020-00123-9 doi (DE-627)SPR039674185 (SPR)s40479-020-00123-9-e DE-627 ger DE-627 rakwb eng 150 610 ASE Kothgassner, Oswald D. verfasserin aut Does treatment method matter? A meta-analysis of the past 20 years of research on therapeutic interventions for self-harm and suicidal ideation in adolescents 2020 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Background Self-harm is a clinically relevant and prevalent behaviour which peaks in adolescence. Given the high prevalence of self-harm, the high levels of psychiatric comorbidity, and its role as a risk factor for suicide, delivering evidence-based care is critical. Methods We conducted a systematic review and meta-analysis of the literature on treating self-harm in adolescents (12–19 years) published in the last 20 years, identifying 25 randomised controlled trials. We calculated the effect of treatment interventions relative to active control conditions in reducing self-harm, suicidal ideation and depressive symptoms. Results Overall, treatment interventions fared slightly better than active controls in decreasing self-harm (d = 0.13, 95% CI 0.04–0.22, p = .004), suicidal ideation (d = 0.31, 95% CI 0.12–0.50, p = .001) and depressive symptoms (d = 0.22, 95% CI 0.07–0.38, p = .006). Subgroup analysis of specific therapies revealed moderate effects of DBT-A in reducing self-harm (d = 0.51, 95% CI 0.18–0.85, p = .002) and suicidal ideation (d = 0.48, 95% CI 0.17–0.80, p = .003), as well as moderate effects of family-centred therapy in the treating suicidal ideation (d = 0.58, 95% CI 0.01–1.15, p = .049). Conclusions The findings of our meta-analysis indicate that, overall, currently available treatments are effective in treating self-harm, suicidal ideation, and depressive symptoms in adolescence. Although the treatment intervention conditions showed only small to moderate effects in comparison to active controls, these differences were statistically significant and are clinically important. Further research is needed to understand the reduction in self-harm within active controls, which may arise due to the natural course of self-harm, or the potential efficacy of treatment as usual and enhanced usual care. Given the significant reduction of self-harm in active control conditions, delivering effective care to a large number of adolescents with self-harm may require developing stepped-care models in clinical practice. Expensive and poorly available treatments should be targeted at young people who most need them. Self-harm (dpeaa)DE-He213 Suicidal ideation (dpeaa)DE-He213 Adolescence (dpeaa)DE-He213 Suicidal behaviour (dpeaa)DE-He213 Depression (dpeaa)DE-He213 Self-injury (dpeaa)DE-He213 Nonsuicidal self-injury (dpeaa)DE-He213 NSSI (dpeaa)DE-He213 Robinson, Kealagh verfasserin aut Goreis, Andreas verfasserin aut Ougrin, Dennis verfasserin aut Plener, Paul L. verfasserin aut Enthalten in Borderline Personality Disorder and Emotion Dysregulation London : BioMed Central, 2014 7(2020), 1 vom: 11. Mai (DE-627)783306415 (DE-600)2766243-3 2051-6673 nnns volume:7 year:2020 number:1 day:11 month:05 https://dx.doi.org/10.1186/s40479-020-00123-9 kostenfrei Volltext GBV_USEFLAG_A SYSFLAG_A GBV_SPRINGER SSG-OLC-PHA GBV_ILN_11 GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_70 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_2014 GBV_ILN_2086 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4326 GBV_ILN_4335 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 7 2020 1 11 05 |
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10.1186/s40479-020-00123-9 doi (DE-627)SPR039674185 (SPR)s40479-020-00123-9-e DE-627 ger DE-627 rakwb eng 150 610 ASE Kothgassner, Oswald D. verfasserin aut Does treatment method matter? A meta-analysis of the past 20 years of research on therapeutic interventions for self-harm and suicidal ideation in adolescents 2020 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Background Self-harm is a clinically relevant and prevalent behaviour which peaks in adolescence. Given the high prevalence of self-harm, the high levels of psychiatric comorbidity, and its role as a risk factor for suicide, delivering evidence-based care is critical. Methods We conducted a systematic review and meta-analysis of the literature on treating self-harm in adolescents (12–19 years) published in the last 20 years, identifying 25 randomised controlled trials. We calculated the effect of treatment interventions relative to active control conditions in reducing self-harm, suicidal ideation and depressive symptoms. Results Overall, treatment interventions fared slightly better than active controls in decreasing self-harm (d = 0.13, 95% CI 0.04–0.22, p = .004), suicidal ideation (d = 0.31, 95% CI 0.12–0.50, p = .001) and depressive symptoms (d = 0.22, 95% CI 0.07–0.38, p = .006). Subgroup analysis of specific therapies revealed moderate effects of DBT-A in reducing self-harm (d = 0.51, 95% CI 0.18–0.85, p = .002) and suicidal ideation (d = 0.48, 95% CI 0.17–0.80, p = .003), as well as moderate effects of family-centred therapy in the treating suicidal ideation (d = 0.58, 95% CI 0.01–1.15, p = .049). Conclusions The findings of our meta-analysis indicate that, overall, currently available treatments are effective in treating self-harm, suicidal ideation, and depressive symptoms in adolescence. Although the treatment intervention conditions showed only small to moderate effects in comparison to active controls, these differences were statistically significant and are clinically important. Further research is needed to understand the reduction in self-harm within active controls, which may arise due to the natural course of self-harm, or the potential efficacy of treatment as usual and enhanced usual care. Given the significant reduction of self-harm in active control conditions, delivering effective care to a large number of adolescents with self-harm may require developing stepped-care models in clinical practice. Expensive and poorly available treatments should be targeted at young people who most need them. Self-harm (dpeaa)DE-He213 Suicidal ideation (dpeaa)DE-He213 Adolescence (dpeaa)DE-He213 Suicidal behaviour (dpeaa)DE-He213 Depression (dpeaa)DE-He213 Self-injury (dpeaa)DE-He213 Nonsuicidal self-injury (dpeaa)DE-He213 NSSI (dpeaa)DE-He213 Robinson, Kealagh verfasserin aut Goreis, Andreas verfasserin aut Ougrin, Dennis verfasserin aut Plener, Paul L. verfasserin aut Enthalten in Borderline Personality Disorder and Emotion Dysregulation London : BioMed Central, 2014 7(2020), 1 vom: 11. Mai (DE-627)783306415 (DE-600)2766243-3 2051-6673 nnns volume:7 year:2020 number:1 day:11 month:05 https://dx.doi.org/10.1186/s40479-020-00123-9 kostenfrei Volltext GBV_USEFLAG_A SYSFLAG_A GBV_SPRINGER SSG-OLC-PHA GBV_ILN_11 GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_70 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_2014 GBV_ILN_2086 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4326 GBV_ILN_4335 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 7 2020 1 11 05 |
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10.1186/s40479-020-00123-9 doi (DE-627)SPR039674185 (SPR)s40479-020-00123-9-e DE-627 ger DE-627 rakwb eng 150 610 ASE Kothgassner, Oswald D. verfasserin aut Does treatment method matter? A meta-analysis of the past 20 years of research on therapeutic interventions for self-harm and suicidal ideation in adolescents 2020 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Background Self-harm is a clinically relevant and prevalent behaviour which peaks in adolescence. Given the high prevalence of self-harm, the high levels of psychiatric comorbidity, and its role as a risk factor for suicide, delivering evidence-based care is critical. Methods We conducted a systematic review and meta-analysis of the literature on treating self-harm in adolescents (12–19 years) published in the last 20 years, identifying 25 randomised controlled trials. We calculated the effect of treatment interventions relative to active control conditions in reducing self-harm, suicidal ideation and depressive symptoms. Results Overall, treatment interventions fared slightly better than active controls in decreasing self-harm (d = 0.13, 95% CI 0.04–0.22, p = .004), suicidal ideation (d = 0.31, 95% CI 0.12–0.50, p = .001) and depressive symptoms (d = 0.22, 95% CI 0.07–0.38, p = .006). Subgroup analysis of specific therapies revealed moderate effects of DBT-A in reducing self-harm (d = 0.51, 95% CI 0.18–0.85, p = .002) and suicidal ideation (d = 0.48, 95% CI 0.17–0.80, p = .003), as well as moderate effects of family-centred therapy in the treating suicidal ideation (d = 0.58, 95% CI 0.01–1.15, p = .049). Conclusions The findings of our meta-analysis indicate that, overall, currently available treatments are effective in treating self-harm, suicidal ideation, and depressive symptoms in adolescence. Although the treatment intervention conditions showed only small to moderate effects in comparison to active controls, these differences were statistically significant and are clinically important. Further research is needed to understand the reduction in self-harm within active controls, which may arise due to the natural course of self-harm, or the potential efficacy of treatment as usual and enhanced usual care. Given the significant reduction of self-harm in active control conditions, delivering effective care to a large number of adolescents with self-harm may require developing stepped-care models in clinical practice. Expensive and poorly available treatments should be targeted at young people who most need them. Self-harm (dpeaa)DE-He213 Suicidal ideation (dpeaa)DE-He213 Adolescence (dpeaa)DE-He213 Suicidal behaviour (dpeaa)DE-He213 Depression (dpeaa)DE-He213 Self-injury (dpeaa)DE-He213 Nonsuicidal self-injury (dpeaa)DE-He213 NSSI (dpeaa)DE-He213 Robinson, Kealagh verfasserin aut Goreis, Andreas verfasserin aut Ougrin, Dennis verfasserin aut Plener, Paul L. verfasserin aut Enthalten in Borderline Personality Disorder and Emotion Dysregulation London : BioMed Central, 2014 7(2020), 1 vom: 11. Mai (DE-627)783306415 (DE-600)2766243-3 2051-6673 nnns volume:7 year:2020 number:1 day:11 month:05 https://dx.doi.org/10.1186/s40479-020-00123-9 kostenfrei Volltext GBV_USEFLAG_A SYSFLAG_A GBV_SPRINGER SSG-OLC-PHA GBV_ILN_11 GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_70 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_2014 GBV_ILN_2086 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4326 GBV_ILN_4335 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 7 2020 1 11 05 |
allfieldsGer |
10.1186/s40479-020-00123-9 doi (DE-627)SPR039674185 (SPR)s40479-020-00123-9-e DE-627 ger DE-627 rakwb eng 150 610 ASE Kothgassner, Oswald D. verfasserin aut Does treatment method matter? A meta-analysis of the past 20 years of research on therapeutic interventions for self-harm and suicidal ideation in adolescents 2020 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Background Self-harm is a clinically relevant and prevalent behaviour which peaks in adolescence. Given the high prevalence of self-harm, the high levels of psychiatric comorbidity, and its role as a risk factor for suicide, delivering evidence-based care is critical. Methods We conducted a systematic review and meta-analysis of the literature on treating self-harm in adolescents (12–19 years) published in the last 20 years, identifying 25 randomised controlled trials. We calculated the effect of treatment interventions relative to active control conditions in reducing self-harm, suicidal ideation and depressive symptoms. Results Overall, treatment interventions fared slightly better than active controls in decreasing self-harm (d = 0.13, 95% CI 0.04–0.22, p = .004), suicidal ideation (d = 0.31, 95% CI 0.12–0.50, p = .001) and depressive symptoms (d = 0.22, 95% CI 0.07–0.38, p = .006). Subgroup analysis of specific therapies revealed moderate effects of DBT-A in reducing self-harm (d = 0.51, 95% CI 0.18–0.85, p = .002) and suicidal ideation (d = 0.48, 95% CI 0.17–0.80, p = .003), as well as moderate effects of family-centred therapy in the treating suicidal ideation (d = 0.58, 95% CI 0.01–1.15, p = .049). Conclusions The findings of our meta-analysis indicate that, overall, currently available treatments are effective in treating self-harm, suicidal ideation, and depressive symptoms in adolescence. Although the treatment intervention conditions showed only small to moderate effects in comparison to active controls, these differences were statistically significant and are clinically important. Further research is needed to understand the reduction in self-harm within active controls, which may arise due to the natural course of self-harm, or the potential efficacy of treatment as usual and enhanced usual care. Given the significant reduction of self-harm in active control conditions, delivering effective care to a large number of adolescents with self-harm may require developing stepped-care models in clinical practice. Expensive and poorly available treatments should be targeted at young people who most need them. Self-harm (dpeaa)DE-He213 Suicidal ideation (dpeaa)DE-He213 Adolescence (dpeaa)DE-He213 Suicidal behaviour (dpeaa)DE-He213 Depression (dpeaa)DE-He213 Self-injury (dpeaa)DE-He213 Nonsuicidal self-injury (dpeaa)DE-He213 NSSI (dpeaa)DE-He213 Robinson, Kealagh verfasserin aut Goreis, Andreas verfasserin aut Ougrin, Dennis verfasserin aut Plener, Paul L. verfasserin aut Enthalten in Borderline Personality Disorder and Emotion Dysregulation London : BioMed Central, 2014 7(2020), 1 vom: 11. Mai (DE-627)783306415 (DE-600)2766243-3 2051-6673 nnns volume:7 year:2020 number:1 day:11 month:05 https://dx.doi.org/10.1186/s40479-020-00123-9 kostenfrei Volltext GBV_USEFLAG_A SYSFLAG_A GBV_SPRINGER SSG-OLC-PHA GBV_ILN_11 GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_70 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_2014 GBV_ILN_2086 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4326 GBV_ILN_4335 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 7 2020 1 11 05 |
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10.1186/s40479-020-00123-9 doi (DE-627)SPR039674185 (SPR)s40479-020-00123-9-e DE-627 ger DE-627 rakwb eng 150 610 ASE Kothgassner, Oswald D. verfasserin aut Does treatment method matter? A meta-analysis of the past 20 years of research on therapeutic interventions for self-harm and suicidal ideation in adolescents 2020 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Background Self-harm is a clinically relevant and prevalent behaviour which peaks in adolescence. Given the high prevalence of self-harm, the high levels of psychiatric comorbidity, and its role as a risk factor for suicide, delivering evidence-based care is critical. Methods We conducted a systematic review and meta-analysis of the literature on treating self-harm in adolescents (12–19 years) published in the last 20 years, identifying 25 randomised controlled trials. We calculated the effect of treatment interventions relative to active control conditions in reducing self-harm, suicidal ideation and depressive symptoms. Results Overall, treatment interventions fared slightly better than active controls in decreasing self-harm (d = 0.13, 95% CI 0.04–0.22, p = .004), suicidal ideation (d = 0.31, 95% CI 0.12–0.50, p = .001) and depressive symptoms (d = 0.22, 95% CI 0.07–0.38, p = .006). Subgroup analysis of specific therapies revealed moderate effects of DBT-A in reducing self-harm (d = 0.51, 95% CI 0.18–0.85, p = .002) and suicidal ideation (d = 0.48, 95% CI 0.17–0.80, p = .003), as well as moderate effects of family-centred therapy in the treating suicidal ideation (d = 0.58, 95% CI 0.01–1.15, p = .049). Conclusions The findings of our meta-analysis indicate that, overall, currently available treatments are effective in treating self-harm, suicidal ideation, and depressive symptoms in adolescence. Although the treatment intervention conditions showed only small to moderate effects in comparison to active controls, these differences were statistically significant and are clinically important. Further research is needed to understand the reduction in self-harm within active controls, which may arise due to the natural course of self-harm, or the potential efficacy of treatment as usual and enhanced usual care. Given the significant reduction of self-harm in active control conditions, delivering effective care to a large number of adolescents with self-harm may require developing stepped-care models in clinical practice. Expensive and poorly available treatments should be targeted at young people who most need them. Self-harm (dpeaa)DE-He213 Suicidal ideation (dpeaa)DE-He213 Adolescence (dpeaa)DE-He213 Suicidal behaviour (dpeaa)DE-He213 Depression (dpeaa)DE-He213 Self-injury (dpeaa)DE-He213 Nonsuicidal self-injury (dpeaa)DE-He213 NSSI (dpeaa)DE-He213 Robinson, Kealagh verfasserin aut Goreis, Andreas verfasserin aut Ougrin, Dennis verfasserin aut Plener, Paul L. verfasserin aut Enthalten in Borderline Personality Disorder and Emotion Dysregulation London : BioMed Central, 2014 7(2020), 1 vom: 11. Mai (DE-627)783306415 (DE-600)2766243-3 2051-6673 nnns volume:7 year:2020 number:1 day:11 month:05 https://dx.doi.org/10.1186/s40479-020-00123-9 kostenfrei Volltext GBV_USEFLAG_A SYSFLAG_A GBV_SPRINGER SSG-OLC-PHA GBV_ILN_11 GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_70 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_2014 GBV_ILN_2086 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4326 GBV_ILN_4335 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 7 2020 1 11 05 |
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150 610 ASE Does treatment method matter? A meta-analysis of the past 20 years of research on therapeutic interventions for self-harm and suicidal ideation in adolescents Self-harm (dpeaa)DE-He213 Suicidal ideation (dpeaa)DE-He213 Adolescence (dpeaa)DE-He213 Suicidal behaviour (dpeaa)DE-He213 Depression (dpeaa)DE-He213 Self-injury (dpeaa)DE-He213 Nonsuicidal self-injury (dpeaa)DE-He213 NSSI (dpeaa)DE-He213 |
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Does treatment method matter? A meta-analysis of the past 20 years of research on therapeutic interventions for self-harm and suicidal ideation in adolescents |
abstract |
Background Self-harm is a clinically relevant and prevalent behaviour which peaks in adolescence. Given the high prevalence of self-harm, the high levels of psychiatric comorbidity, and its role as a risk factor for suicide, delivering evidence-based care is critical. Methods We conducted a systematic review and meta-analysis of the literature on treating self-harm in adolescents (12–19 years) published in the last 20 years, identifying 25 randomised controlled trials. We calculated the effect of treatment interventions relative to active control conditions in reducing self-harm, suicidal ideation and depressive symptoms. Results Overall, treatment interventions fared slightly better than active controls in decreasing self-harm (d = 0.13, 95% CI 0.04–0.22, p = .004), suicidal ideation (d = 0.31, 95% CI 0.12–0.50, p = .001) and depressive symptoms (d = 0.22, 95% CI 0.07–0.38, p = .006). Subgroup analysis of specific therapies revealed moderate effects of DBT-A in reducing self-harm (d = 0.51, 95% CI 0.18–0.85, p = .002) and suicidal ideation (d = 0.48, 95% CI 0.17–0.80, p = .003), as well as moderate effects of family-centred therapy in the treating suicidal ideation (d = 0.58, 95% CI 0.01–1.15, p = .049). Conclusions The findings of our meta-analysis indicate that, overall, currently available treatments are effective in treating self-harm, suicidal ideation, and depressive symptoms in adolescence. Although the treatment intervention conditions showed only small to moderate effects in comparison to active controls, these differences were statistically significant and are clinically important. Further research is needed to understand the reduction in self-harm within active controls, which may arise due to the natural course of self-harm, or the potential efficacy of treatment as usual and enhanced usual care. Given the significant reduction of self-harm in active control conditions, delivering effective care to a large number of adolescents with self-harm may require developing stepped-care models in clinical practice. Expensive and poorly available treatments should be targeted at young people who most need them. |
abstractGer |
Background Self-harm is a clinically relevant and prevalent behaviour which peaks in adolescence. Given the high prevalence of self-harm, the high levels of psychiatric comorbidity, and its role as a risk factor for suicide, delivering evidence-based care is critical. Methods We conducted a systematic review and meta-analysis of the literature on treating self-harm in adolescents (12–19 years) published in the last 20 years, identifying 25 randomised controlled trials. We calculated the effect of treatment interventions relative to active control conditions in reducing self-harm, suicidal ideation and depressive symptoms. Results Overall, treatment interventions fared slightly better than active controls in decreasing self-harm (d = 0.13, 95% CI 0.04–0.22, p = .004), suicidal ideation (d = 0.31, 95% CI 0.12–0.50, p = .001) and depressive symptoms (d = 0.22, 95% CI 0.07–0.38, p = .006). Subgroup analysis of specific therapies revealed moderate effects of DBT-A in reducing self-harm (d = 0.51, 95% CI 0.18–0.85, p = .002) and suicidal ideation (d = 0.48, 95% CI 0.17–0.80, p = .003), as well as moderate effects of family-centred therapy in the treating suicidal ideation (d = 0.58, 95% CI 0.01–1.15, p = .049). Conclusions The findings of our meta-analysis indicate that, overall, currently available treatments are effective in treating self-harm, suicidal ideation, and depressive symptoms in adolescence. Although the treatment intervention conditions showed only small to moderate effects in comparison to active controls, these differences were statistically significant and are clinically important. Further research is needed to understand the reduction in self-harm within active controls, which may arise due to the natural course of self-harm, or the potential efficacy of treatment as usual and enhanced usual care. Given the significant reduction of self-harm in active control conditions, delivering effective care to a large number of adolescents with self-harm may require developing stepped-care models in clinical practice. Expensive and poorly available treatments should be targeted at young people who most need them. |
abstract_unstemmed |
Background Self-harm is a clinically relevant and prevalent behaviour which peaks in adolescence. Given the high prevalence of self-harm, the high levels of psychiatric comorbidity, and its role as a risk factor for suicide, delivering evidence-based care is critical. Methods We conducted a systematic review and meta-analysis of the literature on treating self-harm in adolescents (12–19 years) published in the last 20 years, identifying 25 randomised controlled trials. We calculated the effect of treatment interventions relative to active control conditions in reducing self-harm, suicidal ideation and depressive symptoms. Results Overall, treatment interventions fared slightly better than active controls in decreasing self-harm (d = 0.13, 95% CI 0.04–0.22, p = .004), suicidal ideation (d = 0.31, 95% CI 0.12–0.50, p = .001) and depressive symptoms (d = 0.22, 95% CI 0.07–0.38, p = .006). Subgroup analysis of specific therapies revealed moderate effects of DBT-A in reducing self-harm (d = 0.51, 95% CI 0.18–0.85, p = .002) and suicidal ideation (d = 0.48, 95% CI 0.17–0.80, p = .003), as well as moderate effects of family-centred therapy in the treating suicidal ideation (d = 0.58, 95% CI 0.01–1.15, p = .049). Conclusions The findings of our meta-analysis indicate that, overall, currently available treatments are effective in treating self-harm, suicidal ideation, and depressive symptoms in adolescence. Although the treatment intervention conditions showed only small to moderate effects in comparison to active controls, these differences were statistically significant and are clinically important. Further research is needed to understand the reduction in self-harm within active controls, which may arise due to the natural course of self-harm, or the potential efficacy of treatment as usual and enhanced usual care. Given the significant reduction of self-harm in active control conditions, delivering effective care to a large number of adolescents with self-harm may require developing stepped-care models in clinical practice. Expensive and poorly available treatments should be targeted at young people who most need them. |
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title_short |
Does treatment method matter? A meta-analysis of the past 20 years of research on therapeutic interventions for self-harm and suicidal ideation in adolescents |
url |
https://dx.doi.org/10.1186/s40479-020-00123-9 |
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author2 |
Robinson, Kealagh Goreis, Andreas Ougrin, Dennis Plener, Paul L. |
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Robinson, Kealagh Goreis, Andreas Ougrin, Dennis Plener, Paul L. |
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