Mechanical Reliability and In Vitro Bioactivity of 3D-Printed Porous Polylactic Acid-Hydroxyapatite Scaffold
Abstract The study aimed to investigate the mechanical reliability and in vitro bioactivity of the three-dimensional (3D) printed hydroxyapatite (HA) reinforced polylactic acid (PLA) porous scaffolds. The experiments have been performed to study the effect of HA wt.% in PLA matrix, infill density, a...
Ausführliche Beschreibung
Gespeichert in:
| Autor*in: |
Prakash, Chander [verfasserIn] |
|---|
| Format: |
E-Artikel |
|---|---|
| Sprache: |
Englisch |
| Erschienen: |
2021 |
|---|
| Schlagwörter: |
|---|
| Anmerkung: |
© ASM International 2021. corrected publication 2021 |
|---|
| Übergeordnetes Werk: |
Enthalten in: Journal of materials engineering and performance - New York, NY : Springer, 1992, 30(2021), 7 vom: 04. März, Seite 4946-4956 |
|---|---|
| Übergeordnetes Werk: |
volume:30 ; year:2021 ; number:7 ; day:04 ; month:03 ; pages:4946-4956 |
| Links: |
|---|
| DOI / URN: |
10.1007/s11665-021-05566-x |
|---|
| Katalog-ID: |
SPR044641001 |
|---|
| LEADER | 01000caa a22002652 4500 | ||
|---|---|---|---|
| 001 | SPR044641001 | ||
| 003 | DE-627 | ||
| 005 | 20231014064640.0 | ||
| 007 | cr uuu---uuuuu | ||
| 008 | 210724s2021 xx |||||o 00| ||eng c | ||
| 024 | 7 | |a 10.1007/s11665-021-05566-x |2 doi | |
| 035 | |a (DE-627)SPR044641001 | ||
| 035 | |a (SPR)s11665-021-05566-x-e | ||
| 040 | |a DE-627 |b ger |c DE-627 |e rakwb | ||
| 041 | |a eng | ||
| 100 | 1 | |a Prakash, Chander |e verfasserin |4 aut | |
| 245 | 1 | 0 | |a Mechanical Reliability and In Vitro Bioactivity of 3D-Printed Porous Polylactic Acid-Hydroxyapatite Scaffold |
| 264 | 1 | |c 2021 | |
| 336 | |a Text |b txt |2 rdacontent | ||
| 337 | |a Computermedien |b c |2 rdamedia | ||
| 338 | |a Online-Ressource |b cr |2 rdacarrier | ||
| 500 | |a © ASM International 2021. corrected publication 2021 | ||
| 520 | |a Abstract The study aimed to investigate the mechanical reliability and in vitro bioactivity of the three-dimensional (3D) printed hydroxyapatite (HA) reinforced polylactic acid (PLA) porous scaffolds. The experiments have been performed to study the effect of HA wt.% in PLA matrix, infill density, and post-printing thermal-stimulus on the flexural and compressive strength. Next to this, the best combination of input parameters, in-response of the observed mechanical properties, was determined to print the test specimens for the analysis of reliability, through Weibull distribution. Further, the fracture morphology of the developed PLA/HA porous scaffolds has been investigated, using scanning electron microscopy, to observe the involved fracture mechanism. Moreover, the in vitro cell-culture with osteoblastic bone marrow mesenchymal stem cells-lines has been studied after 1, 3, and 7 days of seeding. The results of the study highlighted that the processing parameters have a strong impact on the mechanical properties of the 3D printed porous scaffolds. Further, the in vitro analysis showed excellent growth, proliferation, and differentiation of osteoplastic cells. Along with these, the result of the Weibull distribution advocated that the printed porous scaffolds are mechanically reliable. Overall, the present study unequivocally advocates that the 3D printed PLA/HA scaffold can be used for potential tissue engineering and biomedical applications. | ||
| 650 | 4 | |a 3D printing |7 (dpeaa)DE-He213 | |
| 650 | 4 | |a hydroxyapatite |7 (dpeaa)DE-He213 | |
| 650 | 4 | |a in vitro bioactivity |7 (dpeaa)DE-He213 | |
| 650 | 4 | |a mechanical properties |7 (dpeaa)DE-He213 | |
| 650 | 4 | |a polylactic acid |7 (dpeaa)DE-He213 | |
| 650 | 4 | |a scaffolds |7 (dpeaa)DE-He213 | |
| 650 | 4 | |a Weibull distribution |7 (dpeaa)DE-He213 | |
| 700 | 1 | |a Singh, Gurminder |4 aut | |
| 700 | 1 | |a Singh, Sunpreet |0 (orcid)0000-0001-9592-4828 |4 aut | |
| 700 | 1 | |a Linda, W. L. |4 aut | |
| 700 | 1 | |a Zheng, H. Y. |4 aut | |
| 700 | 1 | |a Ramakrishna, Seeram |4 aut | |
| 700 | 1 | |a Narayan, Roger |4 aut | |
| 773 | 0 | 8 | |i Enthalten in |t Journal of materials engineering and performance |d New York, NY : Springer, 1992 |g 30(2021), 7 vom: 04. März, Seite 4946-4956 |w (DE-627)329975447 |w (DE-600)2048384-3 |x 1544-1024 |7 nnns |
| 773 | 1 | 8 | |g volume:30 |g year:2021 |g number:7 |g day:04 |g month:03 |g pages:4946-4956 |
| 856 | 4 | 0 | |u https://dx.doi.org/10.1007/s11665-021-05566-x |z lizenzpflichtig |3 Volltext |
| 912 | |a GBV_USEFLAG_A | ||
| 912 | |a SYSFLAG_A | ||
| 912 | |a GBV_SPRINGER | ||
| 912 | |a GBV_ILN_11 | ||
| 912 | |a GBV_ILN_20 | ||
| 912 | |a GBV_ILN_22 | ||
| 912 | |a GBV_ILN_23 | ||
| 912 | |a GBV_ILN_24 | ||
| 912 | |a GBV_ILN_31 | ||
| 912 | |a GBV_ILN_32 | ||
| 912 | |a GBV_ILN_39 | ||
| 912 | |a GBV_ILN_40 | ||
| 912 | |a GBV_ILN_60 | ||
| 912 | |a GBV_ILN_62 | ||
| 912 | |a GBV_ILN_63 | ||
| 912 | |a GBV_ILN_65 | ||
| 912 | |a GBV_ILN_69 | ||
| 912 | |a GBV_ILN_70 | ||
| 912 | |a GBV_ILN_73 | ||
| 912 | |a GBV_ILN_74 | ||
| 912 | |a GBV_ILN_90 | ||
| 912 | |a GBV_ILN_95 | ||
| 912 | |a GBV_ILN_100 | ||
| 912 | |a GBV_ILN_105 | ||
| 912 | |a GBV_ILN_110 | ||
| 912 | |a GBV_ILN_120 | ||
| 912 | |a GBV_ILN_138 | ||
| 912 | |a GBV_ILN_150 | ||
| 912 | |a GBV_ILN_151 | ||
| 912 | |a GBV_ILN_152 | ||
| 912 | |a GBV_ILN_161 | ||
| 912 | |a GBV_ILN_170 | ||
| 912 | |a GBV_ILN_171 | ||
| 912 | |a GBV_ILN_187 | ||
| 912 | |a GBV_ILN_213 | ||
| 912 | |a GBV_ILN_224 | ||
| 912 | |a GBV_ILN_230 | ||
| 912 | |a GBV_ILN_250 | ||
| 912 | |a GBV_ILN_281 | ||
| 912 | |a GBV_ILN_285 | ||
| 912 | |a GBV_ILN_293 | ||
| 912 | |a GBV_ILN_370 | ||
| 912 | |a GBV_ILN_602 | ||
| 912 | |a GBV_ILN_636 | ||
| 912 | |a GBV_ILN_702 | ||
| 912 | |a GBV_ILN_2001 | ||
| 912 | |a GBV_ILN_2003 | ||
| 912 | |a GBV_ILN_2004 | ||
| 912 | |a GBV_ILN_2005 | ||
| 912 | |a GBV_ILN_2006 | ||
| 912 | |a GBV_ILN_2007 | ||
| 912 | |a GBV_ILN_2008 | ||
| 912 | |a GBV_ILN_2009 | ||
| 912 | |a GBV_ILN_2010 | ||
| 912 | |a GBV_ILN_2011 | ||
| 912 | |a GBV_ILN_2014 | ||
| 912 | |a GBV_ILN_2015 | ||
| 912 | |a GBV_ILN_2020 | ||
| 912 | |a GBV_ILN_2021 | ||
| 912 | |a GBV_ILN_2025 | ||
| 912 | |a GBV_ILN_2026 | ||
| 912 | |a GBV_ILN_2027 | ||
| 912 | |a GBV_ILN_2031 | ||
| 912 | |a GBV_ILN_2034 | ||
| 912 | |a GBV_ILN_2037 | ||
| 912 | |a GBV_ILN_2038 | ||
| 912 | |a GBV_ILN_2039 | ||
| 912 | |a GBV_ILN_2044 | ||
| 912 | |a GBV_ILN_2048 | ||
| 912 | |a GBV_ILN_2049 | ||
| 912 | |a GBV_ILN_2050 | ||
| 912 | |a GBV_ILN_2055 | ||
| 912 | |a GBV_ILN_2056 | ||
| 912 | |a GBV_ILN_2057 | ||
| 912 | |a GBV_ILN_2059 | ||
| 912 | |a GBV_ILN_2061 | ||
| 912 | |a GBV_ILN_2064 | ||
| 912 | |a GBV_ILN_2065 | ||
| 912 | |a GBV_ILN_2068 | ||
| 912 | |a GBV_ILN_2088 | ||
| 912 | |a GBV_ILN_2093 | ||
| 912 | |a GBV_ILN_2106 | ||
| 912 | |a GBV_ILN_2107 | ||
| 912 | |a GBV_ILN_2108 | ||
| 912 | |a GBV_ILN_2110 | ||
| 912 | |a GBV_ILN_2111 | ||
| 912 | |a GBV_ILN_2112 | ||
| 912 | |a GBV_ILN_2113 | ||
| 912 | |a GBV_ILN_2118 | ||
| 912 | |a GBV_ILN_2122 | ||
| 912 | |a GBV_ILN_2129 | ||
| 912 | |a GBV_ILN_2143 | ||
| 912 | |a GBV_ILN_2144 | ||
| 912 | |a GBV_ILN_2147 | ||
| 912 | |a GBV_ILN_2148 | ||
| 912 | |a GBV_ILN_2152 | ||
| 912 | |a GBV_ILN_2153 | ||
| 912 | |a GBV_ILN_2188 | ||
| 912 | |a GBV_ILN_2190 | ||
| 912 | |a GBV_ILN_2232 | ||
| 912 | |a GBV_ILN_2336 | ||
| 912 | |a GBV_ILN_2446 | ||
| 912 | |a GBV_ILN_2470 | ||
| 912 | |a GBV_ILN_2472 | ||
| 912 | |a GBV_ILN_2507 | ||
| 912 | |a GBV_ILN_2522 | ||
| 912 | |a GBV_ILN_2548 | ||
| 912 | |a GBV_ILN_4035 | ||
| 912 | |a GBV_ILN_4037 | ||
| 912 | |a GBV_ILN_4046 | ||
| 912 | |a GBV_ILN_4112 | ||
| 912 | |a GBV_ILN_4125 | ||
| 912 | |a GBV_ILN_4126 | ||
| 912 | |a GBV_ILN_4242 | ||
| 912 | |a GBV_ILN_4246 | ||
| 912 | |a GBV_ILN_4249 | ||
| 912 | |a GBV_ILN_4251 | ||
| 912 | |a GBV_ILN_4305 | ||
| 912 | |a GBV_ILN_4306 | ||
| 912 | |a GBV_ILN_4307 | ||
| 912 | |a GBV_ILN_4313 | ||
| 912 | |a GBV_ILN_4322 | ||
| 912 | |a GBV_ILN_4323 | ||
| 912 | |a GBV_ILN_4324 | ||
| 912 | |a GBV_ILN_4325 | ||
| 912 | |a GBV_ILN_4326 | ||
| 912 | |a GBV_ILN_4328 | ||
| 912 | |a GBV_ILN_4333 | ||
| 912 | |a GBV_ILN_4334 | ||
| 912 | |a GBV_ILN_4335 | ||
| 912 | |a GBV_ILN_4336 | ||
| 912 | |a GBV_ILN_4338 | ||
| 912 | |a GBV_ILN_4393 | ||
| 912 | |a GBV_ILN_4700 | ||
| 951 | |a AR | ||
| 952 | |d 30 |j 2021 |e 7 |b 04 |c 03 |h 4946-4956 | ||
| author_variant |
c p cp g s gs s s ss w l l wl wll h y z hy hyz s r sr r n rn |
|---|---|
| matchkey_str |
article:15441024:2021----::ehncleibltadnirbociiyfdrneprupllci |
| hierarchy_sort_str |
2021 |
| publishDate |
2021 |
| allfields |
10.1007/s11665-021-05566-x doi (DE-627)SPR044641001 (SPR)s11665-021-05566-x-e DE-627 ger DE-627 rakwb eng Prakash, Chander verfasserin aut Mechanical Reliability and In Vitro Bioactivity of 3D-Printed Porous Polylactic Acid-Hydroxyapatite Scaffold 2021 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier © ASM International 2021. corrected publication 2021 Abstract The study aimed to investigate the mechanical reliability and in vitro bioactivity of the three-dimensional (3D) printed hydroxyapatite (HA) reinforced polylactic acid (PLA) porous scaffolds. The experiments have been performed to study the effect of HA wt.% in PLA matrix, infill density, and post-printing thermal-stimulus on the flexural and compressive strength. Next to this, the best combination of input parameters, in-response of the observed mechanical properties, was determined to print the test specimens for the analysis of reliability, through Weibull distribution. Further, the fracture morphology of the developed PLA/HA porous scaffolds has been investigated, using scanning electron microscopy, to observe the involved fracture mechanism. Moreover, the in vitro cell-culture with osteoblastic bone marrow mesenchymal stem cells-lines has been studied after 1, 3, and 7 days of seeding. The results of the study highlighted that the processing parameters have a strong impact on the mechanical properties of the 3D printed porous scaffolds. Further, the in vitro analysis showed excellent growth, proliferation, and differentiation of osteoplastic cells. Along with these, the result of the Weibull distribution advocated that the printed porous scaffolds are mechanically reliable. Overall, the present study unequivocally advocates that the 3D printed PLA/HA scaffold can be used for potential tissue engineering and biomedical applications. 3D printing (dpeaa)DE-He213 hydroxyapatite (dpeaa)DE-He213 in vitro bioactivity (dpeaa)DE-He213 mechanical properties (dpeaa)DE-He213 polylactic acid (dpeaa)DE-He213 scaffolds (dpeaa)DE-He213 Weibull distribution (dpeaa)DE-He213 Singh, Gurminder aut Singh, Sunpreet (orcid)0000-0001-9592-4828 aut Linda, W. L. aut Zheng, H. Y. aut Ramakrishna, Seeram aut Narayan, Roger aut Enthalten in Journal of materials engineering and performance New York, NY : Springer, 1992 30(2021), 7 vom: 04. März, Seite 4946-4956 (DE-627)329975447 (DE-600)2048384-3 1544-1024 nnns volume:30 year:2021 number:7 day:04 month:03 pages:4946-4956 https://dx.doi.org/10.1007/s11665-021-05566-x lizenzpflichtig Volltext GBV_USEFLAG_A SYSFLAG_A GBV_SPRINGER GBV_ILN_11 GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_32 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_70 GBV_ILN_73 GBV_ILN_74 GBV_ILN_90 GBV_ILN_95 GBV_ILN_100 GBV_ILN_105 GBV_ILN_110 GBV_ILN_120 GBV_ILN_138 GBV_ILN_150 GBV_ILN_151 GBV_ILN_152 GBV_ILN_161 GBV_ILN_170 GBV_ILN_171 GBV_ILN_187 GBV_ILN_213 GBV_ILN_224 GBV_ILN_230 GBV_ILN_250 GBV_ILN_281 GBV_ILN_285 GBV_ILN_293 GBV_ILN_370 GBV_ILN_602 GBV_ILN_636 GBV_ILN_702 GBV_ILN_2001 GBV_ILN_2003 GBV_ILN_2004 GBV_ILN_2005 GBV_ILN_2006 GBV_ILN_2007 GBV_ILN_2008 GBV_ILN_2009 GBV_ILN_2010 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2015 GBV_ILN_2020 GBV_ILN_2021 GBV_ILN_2025 GBV_ILN_2026 GBV_ILN_2027 GBV_ILN_2031 GBV_ILN_2034 GBV_ILN_2037 GBV_ILN_2038 GBV_ILN_2039 GBV_ILN_2044 GBV_ILN_2048 GBV_ILN_2049 GBV_ILN_2050 GBV_ILN_2055 GBV_ILN_2056 GBV_ILN_2057 GBV_ILN_2059 GBV_ILN_2061 GBV_ILN_2064 GBV_ILN_2065 GBV_ILN_2068 GBV_ILN_2088 GBV_ILN_2093 GBV_ILN_2106 GBV_ILN_2107 GBV_ILN_2108 GBV_ILN_2110 GBV_ILN_2111 GBV_ILN_2112 GBV_ILN_2113 GBV_ILN_2118 GBV_ILN_2122 GBV_ILN_2129 GBV_ILN_2143 GBV_ILN_2144 GBV_ILN_2147 GBV_ILN_2148 GBV_ILN_2152 GBV_ILN_2153 GBV_ILN_2188 GBV_ILN_2190 GBV_ILN_2232 GBV_ILN_2336 GBV_ILN_2446 GBV_ILN_2470 GBV_ILN_2472 GBV_ILN_2507 GBV_ILN_2522 GBV_ILN_2548 GBV_ILN_4035 GBV_ILN_4037 GBV_ILN_4046 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4242 GBV_ILN_4246 GBV_ILN_4249 GBV_ILN_4251 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4326 GBV_ILN_4328 GBV_ILN_4333 GBV_ILN_4334 GBV_ILN_4335 GBV_ILN_4336 GBV_ILN_4338 GBV_ILN_4393 GBV_ILN_4700 AR 30 2021 7 04 03 4946-4956 |
| spelling |
10.1007/s11665-021-05566-x doi (DE-627)SPR044641001 (SPR)s11665-021-05566-x-e DE-627 ger DE-627 rakwb eng Prakash, Chander verfasserin aut Mechanical Reliability and In Vitro Bioactivity of 3D-Printed Porous Polylactic Acid-Hydroxyapatite Scaffold 2021 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier © ASM International 2021. corrected publication 2021 Abstract The study aimed to investigate the mechanical reliability and in vitro bioactivity of the three-dimensional (3D) printed hydroxyapatite (HA) reinforced polylactic acid (PLA) porous scaffolds. The experiments have been performed to study the effect of HA wt.% in PLA matrix, infill density, and post-printing thermal-stimulus on the flexural and compressive strength. Next to this, the best combination of input parameters, in-response of the observed mechanical properties, was determined to print the test specimens for the analysis of reliability, through Weibull distribution. Further, the fracture morphology of the developed PLA/HA porous scaffolds has been investigated, using scanning electron microscopy, to observe the involved fracture mechanism. Moreover, the in vitro cell-culture with osteoblastic bone marrow mesenchymal stem cells-lines has been studied after 1, 3, and 7 days of seeding. The results of the study highlighted that the processing parameters have a strong impact on the mechanical properties of the 3D printed porous scaffolds. Further, the in vitro analysis showed excellent growth, proliferation, and differentiation of osteoplastic cells. Along with these, the result of the Weibull distribution advocated that the printed porous scaffolds are mechanically reliable. Overall, the present study unequivocally advocates that the 3D printed PLA/HA scaffold can be used for potential tissue engineering and biomedical applications. 3D printing (dpeaa)DE-He213 hydroxyapatite (dpeaa)DE-He213 in vitro bioactivity (dpeaa)DE-He213 mechanical properties (dpeaa)DE-He213 polylactic acid (dpeaa)DE-He213 scaffolds (dpeaa)DE-He213 Weibull distribution (dpeaa)DE-He213 Singh, Gurminder aut Singh, Sunpreet (orcid)0000-0001-9592-4828 aut Linda, W. L. aut Zheng, H. Y. aut Ramakrishna, Seeram aut Narayan, Roger aut Enthalten in Journal of materials engineering and performance New York, NY : Springer, 1992 30(2021), 7 vom: 04. März, Seite 4946-4956 (DE-627)329975447 (DE-600)2048384-3 1544-1024 nnns volume:30 year:2021 number:7 day:04 month:03 pages:4946-4956 https://dx.doi.org/10.1007/s11665-021-05566-x lizenzpflichtig Volltext GBV_USEFLAG_A SYSFLAG_A GBV_SPRINGER GBV_ILN_11 GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_32 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_70 GBV_ILN_73 GBV_ILN_74 GBV_ILN_90 GBV_ILN_95 GBV_ILN_100 GBV_ILN_105 GBV_ILN_110 GBV_ILN_120 GBV_ILN_138 GBV_ILN_150 GBV_ILN_151 GBV_ILN_152 GBV_ILN_161 GBV_ILN_170 GBV_ILN_171 GBV_ILN_187 GBV_ILN_213 GBV_ILN_224 GBV_ILN_230 GBV_ILN_250 GBV_ILN_281 GBV_ILN_285 GBV_ILN_293 GBV_ILN_370 GBV_ILN_602 GBV_ILN_636 GBV_ILN_702 GBV_ILN_2001 GBV_ILN_2003 GBV_ILN_2004 GBV_ILN_2005 GBV_ILN_2006 GBV_ILN_2007 GBV_ILN_2008 GBV_ILN_2009 GBV_ILN_2010 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2015 GBV_ILN_2020 GBV_ILN_2021 GBV_ILN_2025 GBV_ILN_2026 GBV_ILN_2027 GBV_ILN_2031 GBV_ILN_2034 GBV_ILN_2037 GBV_ILN_2038 GBV_ILN_2039 GBV_ILN_2044 GBV_ILN_2048 GBV_ILN_2049 GBV_ILN_2050 GBV_ILN_2055 GBV_ILN_2056 GBV_ILN_2057 GBV_ILN_2059 GBV_ILN_2061 GBV_ILN_2064 GBV_ILN_2065 GBV_ILN_2068 GBV_ILN_2088 GBV_ILN_2093 GBV_ILN_2106 GBV_ILN_2107 GBV_ILN_2108 GBV_ILN_2110 GBV_ILN_2111 GBV_ILN_2112 GBV_ILN_2113 GBV_ILN_2118 GBV_ILN_2122 GBV_ILN_2129 GBV_ILN_2143 GBV_ILN_2144 GBV_ILN_2147 GBV_ILN_2148 GBV_ILN_2152 GBV_ILN_2153 GBV_ILN_2188 GBV_ILN_2190 GBV_ILN_2232 GBV_ILN_2336 GBV_ILN_2446 GBV_ILN_2470 GBV_ILN_2472 GBV_ILN_2507 GBV_ILN_2522 GBV_ILN_2548 GBV_ILN_4035 GBV_ILN_4037 GBV_ILN_4046 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4242 GBV_ILN_4246 GBV_ILN_4249 GBV_ILN_4251 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4326 GBV_ILN_4328 GBV_ILN_4333 GBV_ILN_4334 GBV_ILN_4335 GBV_ILN_4336 GBV_ILN_4338 GBV_ILN_4393 GBV_ILN_4700 AR 30 2021 7 04 03 4946-4956 |
| allfields_unstemmed |
10.1007/s11665-021-05566-x doi (DE-627)SPR044641001 (SPR)s11665-021-05566-x-e DE-627 ger DE-627 rakwb eng Prakash, Chander verfasserin aut Mechanical Reliability and In Vitro Bioactivity of 3D-Printed Porous Polylactic Acid-Hydroxyapatite Scaffold 2021 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier © ASM International 2021. corrected publication 2021 Abstract The study aimed to investigate the mechanical reliability and in vitro bioactivity of the three-dimensional (3D) printed hydroxyapatite (HA) reinforced polylactic acid (PLA) porous scaffolds. The experiments have been performed to study the effect of HA wt.% in PLA matrix, infill density, and post-printing thermal-stimulus on the flexural and compressive strength. Next to this, the best combination of input parameters, in-response of the observed mechanical properties, was determined to print the test specimens for the analysis of reliability, through Weibull distribution. Further, the fracture morphology of the developed PLA/HA porous scaffolds has been investigated, using scanning electron microscopy, to observe the involved fracture mechanism. Moreover, the in vitro cell-culture with osteoblastic bone marrow mesenchymal stem cells-lines has been studied after 1, 3, and 7 days of seeding. The results of the study highlighted that the processing parameters have a strong impact on the mechanical properties of the 3D printed porous scaffolds. Further, the in vitro analysis showed excellent growth, proliferation, and differentiation of osteoplastic cells. Along with these, the result of the Weibull distribution advocated that the printed porous scaffolds are mechanically reliable. Overall, the present study unequivocally advocates that the 3D printed PLA/HA scaffold can be used for potential tissue engineering and biomedical applications. 3D printing (dpeaa)DE-He213 hydroxyapatite (dpeaa)DE-He213 in vitro bioactivity (dpeaa)DE-He213 mechanical properties (dpeaa)DE-He213 polylactic acid (dpeaa)DE-He213 scaffolds (dpeaa)DE-He213 Weibull distribution (dpeaa)DE-He213 Singh, Gurminder aut Singh, Sunpreet (orcid)0000-0001-9592-4828 aut Linda, W. L. aut Zheng, H. Y. aut Ramakrishna, Seeram aut Narayan, Roger aut Enthalten in Journal of materials engineering and performance New York, NY : Springer, 1992 30(2021), 7 vom: 04. März, Seite 4946-4956 (DE-627)329975447 (DE-600)2048384-3 1544-1024 nnns volume:30 year:2021 number:7 day:04 month:03 pages:4946-4956 https://dx.doi.org/10.1007/s11665-021-05566-x lizenzpflichtig Volltext GBV_USEFLAG_A SYSFLAG_A GBV_SPRINGER GBV_ILN_11 GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_32 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_70 GBV_ILN_73 GBV_ILN_74 GBV_ILN_90 GBV_ILN_95 GBV_ILN_100 GBV_ILN_105 GBV_ILN_110 GBV_ILN_120 GBV_ILN_138 GBV_ILN_150 GBV_ILN_151 GBV_ILN_152 GBV_ILN_161 GBV_ILN_170 GBV_ILN_171 GBV_ILN_187 GBV_ILN_213 GBV_ILN_224 GBV_ILN_230 GBV_ILN_250 GBV_ILN_281 GBV_ILN_285 GBV_ILN_293 GBV_ILN_370 GBV_ILN_602 GBV_ILN_636 GBV_ILN_702 GBV_ILN_2001 GBV_ILN_2003 GBV_ILN_2004 GBV_ILN_2005 GBV_ILN_2006 GBV_ILN_2007 GBV_ILN_2008 GBV_ILN_2009 GBV_ILN_2010 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2015 GBV_ILN_2020 GBV_ILN_2021 GBV_ILN_2025 GBV_ILN_2026 GBV_ILN_2027 GBV_ILN_2031 GBV_ILN_2034 GBV_ILN_2037 GBV_ILN_2038 GBV_ILN_2039 GBV_ILN_2044 GBV_ILN_2048 GBV_ILN_2049 GBV_ILN_2050 GBV_ILN_2055 GBV_ILN_2056 GBV_ILN_2057 GBV_ILN_2059 GBV_ILN_2061 GBV_ILN_2064 GBV_ILN_2065 GBV_ILN_2068 GBV_ILN_2088 GBV_ILN_2093 GBV_ILN_2106 GBV_ILN_2107 GBV_ILN_2108 GBV_ILN_2110 GBV_ILN_2111 GBV_ILN_2112 GBV_ILN_2113 GBV_ILN_2118 GBV_ILN_2122 GBV_ILN_2129 GBV_ILN_2143 GBV_ILN_2144 GBV_ILN_2147 GBV_ILN_2148 GBV_ILN_2152 GBV_ILN_2153 GBV_ILN_2188 GBV_ILN_2190 GBV_ILN_2232 GBV_ILN_2336 GBV_ILN_2446 GBV_ILN_2470 GBV_ILN_2472 GBV_ILN_2507 GBV_ILN_2522 GBV_ILN_2548 GBV_ILN_4035 GBV_ILN_4037 GBV_ILN_4046 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4242 GBV_ILN_4246 GBV_ILN_4249 GBV_ILN_4251 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4326 GBV_ILN_4328 GBV_ILN_4333 GBV_ILN_4334 GBV_ILN_4335 GBV_ILN_4336 GBV_ILN_4338 GBV_ILN_4393 GBV_ILN_4700 AR 30 2021 7 04 03 4946-4956 |
| allfieldsGer |
10.1007/s11665-021-05566-x doi (DE-627)SPR044641001 (SPR)s11665-021-05566-x-e DE-627 ger DE-627 rakwb eng Prakash, Chander verfasserin aut Mechanical Reliability and In Vitro Bioactivity of 3D-Printed Porous Polylactic Acid-Hydroxyapatite Scaffold 2021 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier © ASM International 2021. corrected publication 2021 Abstract The study aimed to investigate the mechanical reliability and in vitro bioactivity of the three-dimensional (3D) printed hydroxyapatite (HA) reinforced polylactic acid (PLA) porous scaffolds. The experiments have been performed to study the effect of HA wt.% in PLA matrix, infill density, and post-printing thermal-stimulus on the flexural and compressive strength. Next to this, the best combination of input parameters, in-response of the observed mechanical properties, was determined to print the test specimens for the analysis of reliability, through Weibull distribution. Further, the fracture morphology of the developed PLA/HA porous scaffolds has been investigated, using scanning electron microscopy, to observe the involved fracture mechanism. Moreover, the in vitro cell-culture with osteoblastic bone marrow mesenchymal stem cells-lines has been studied after 1, 3, and 7 days of seeding. The results of the study highlighted that the processing parameters have a strong impact on the mechanical properties of the 3D printed porous scaffolds. Further, the in vitro analysis showed excellent growth, proliferation, and differentiation of osteoplastic cells. Along with these, the result of the Weibull distribution advocated that the printed porous scaffolds are mechanically reliable. Overall, the present study unequivocally advocates that the 3D printed PLA/HA scaffold can be used for potential tissue engineering and biomedical applications. 3D printing (dpeaa)DE-He213 hydroxyapatite (dpeaa)DE-He213 in vitro bioactivity (dpeaa)DE-He213 mechanical properties (dpeaa)DE-He213 polylactic acid (dpeaa)DE-He213 scaffolds (dpeaa)DE-He213 Weibull distribution (dpeaa)DE-He213 Singh, Gurminder aut Singh, Sunpreet (orcid)0000-0001-9592-4828 aut Linda, W. L. aut Zheng, H. Y. aut Ramakrishna, Seeram aut Narayan, Roger aut Enthalten in Journal of materials engineering and performance New York, NY : Springer, 1992 30(2021), 7 vom: 04. März, Seite 4946-4956 (DE-627)329975447 (DE-600)2048384-3 1544-1024 nnns volume:30 year:2021 number:7 day:04 month:03 pages:4946-4956 https://dx.doi.org/10.1007/s11665-021-05566-x lizenzpflichtig Volltext GBV_USEFLAG_A SYSFLAG_A GBV_SPRINGER GBV_ILN_11 GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_32 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_70 GBV_ILN_73 GBV_ILN_74 GBV_ILN_90 GBV_ILN_95 GBV_ILN_100 GBV_ILN_105 GBV_ILN_110 GBV_ILN_120 GBV_ILN_138 GBV_ILN_150 GBV_ILN_151 GBV_ILN_152 GBV_ILN_161 GBV_ILN_170 GBV_ILN_171 GBV_ILN_187 GBV_ILN_213 GBV_ILN_224 GBV_ILN_230 GBV_ILN_250 GBV_ILN_281 GBV_ILN_285 GBV_ILN_293 GBV_ILN_370 GBV_ILN_602 GBV_ILN_636 GBV_ILN_702 GBV_ILN_2001 GBV_ILN_2003 GBV_ILN_2004 GBV_ILN_2005 GBV_ILN_2006 GBV_ILN_2007 GBV_ILN_2008 GBV_ILN_2009 GBV_ILN_2010 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2015 GBV_ILN_2020 GBV_ILN_2021 GBV_ILN_2025 GBV_ILN_2026 GBV_ILN_2027 GBV_ILN_2031 GBV_ILN_2034 GBV_ILN_2037 GBV_ILN_2038 GBV_ILN_2039 GBV_ILN_2044 GBV_ILN_2048 GBV_ILN_2049 GBV_ILN_2050 GBV_ILN_2055 GBV_ILN_2056 GBV_ILN_2057 GBV_ILN_2059 GBV_ILN_2061 GBV_ILN_2064 GBV_ILN_2065 GBV_ILN_2068 GBV_ILN_2088 GBV_ILN_2093 GBV_ILN_2106 GBV_ILN_2107 GBV_ILN_2108 GBV_ILN_2110 GBV_ILN_2111 GBV_ILN_2112 GBV_ILN_2113 GBV_ILN_2118 GBV_ILN_2122 GBV_ILN_2129 GBV_ILN_2143 GBV_ILN_2144 GBV_ILN_2147 GBV_ILN_2148 GBV_ILN_2152 GBV_ILN_2153 GBV_ILN_2188 GBV_ILN_2190 GBV_ILN_2232 GBV_ILN_2336 GBV_ILN_2446 GBV_ILN_2470 GBV_ILN_2472 GBV_ILN_2507 GBV_ILN_2522 GBV_ILN_2548 GBV_ILN_4035 GBV_ILN_4037 GBV_ILN_4046 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4242 GBV_ILN_4246 GBV_ILN_4249 GBV_ILN_4251 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4326 GBV_ILN_4328 GBV_ILN_4333 GBV_ILN_4334 GBV_ILN_4335 GBV_ILN_4336 GBV_ILN_4338 GBV_ILN_4393 GBV_ILN_4700 AR 30 2021 7 04 03 4946-4956 |
| allfieldsSound |
10.1007/s11665-021-05566-x doi (DE-627)SPR044641001 (SPR)s11665-021-05566-x-e DE-627 ger DE-627 rakwb eng Prakash, Chander verfasserin aut Mechanical Reliability and In Vitro Bioactivity of 3D-Printed Porous Polylactic Acid-Hydroxyapatite Scaffold 2021 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier © ASM International 2021. corrected publication 2021 Abstract The study aimed to investigate the mechanical reliability and in vitro bioactivity of the three-dimensional (3D) printed hydroxyapatite (HA) reinforced polylactic acid (PLA) porous scaffolds. The experiments have been performed to study the effect of HA wt.% in PLA matrix, infill density, and post-printing thermal-stimulus on the flexural and compressive strength. Next to this, the best combination of input parameters, in-response of the observed mechanical properties, was determined to print the test specimens for the analysis of reliability, through Weibull distribution. Further, the fracture morphology of the developed PLA/HA porous scaffolds has been investigated, using scanning electron microscopy, to observe the involved fracture mechanism. Moreover, the in vitro cell-culture with osteoblastic bone marrow mesenchymal stem cells-lines has been studied after 1, 3, and 7 days of seeding. The results of the study highlighted that the processing parameters have a strong impact on the mechanical properties of the 3D printed porous scaffolds. Further, the in vitro analysis showed excellent growth, proliferation, and differentiation of osteoplastic cells. Along with these, the result of the Weibull distribution advocated that the printed porous scaffolds are mechanically reliable. Overall, the present study unequivocally advocates that the 3D printed PLA/HA scaffold can be used for potential tissue engineering and biomedical applications. 3D printing (dpeaa)DE-He213 hydroxyapatite (dpeaa)DE-He213 in vitro bioactivity (dpeaa)DE-He213 mechanical properties (dpeaa)DE-He213 polylactic acid (dpeaa)DE-He213 scaffolds (dpeaa)DE-He213 Weibull distribution (dpeaa)DE-He213 Singh, Gurminder aut Singh, Sunpreet (orcid)0000-0001-9592-4828 aut Linda, W. L. aut Zheng, H. Y. aut Ramakrishna, Seeram aut Narayan, Roger aut Enthalten in Journal of materials engineering and performance New York, NY : Springer, 1992 30(2021), 7 vom: 04. März, Seite 4946-4956 (DE-627)329975447 (DE-600)2048384-3 1544-1024 nnns volume:30 year:2021 number:7 day:04 month:03 pages:4946-4956 https://dx.doi.org/10.1007/s11665-021-05566-x lizenzpflichtig Volltext GBV_USEFLAG_A SYSFLAG_A GBV_SPRINGER GBV_ILN_11 GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_32 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_70 GBV_ILN_73 GBV_ILN_74 GBV_ILN_90 GBV_ILN_95 GBV_ILN_100 GBV_ILN_105 GBV_ILN_110 GBV_ILN_120 GBV_ILN_138 GBV_ILN_150 GBV_ILN_151 GBV_ILN_152 GBV_ILN_161 GBV_ILN_170 GBV_ILN_171 GBV_ILN_187 GBV_ILN_213 GBV_ILN_224 GBV_ILN_230 GBV_ILN_250 GBV_ILN_281 GBV_ILN_285 GBV_ILN_293 GBV_ILN_370 GBV_ILN_602 GBV_ILN_636 GBV_ILN_702 GBV_ILN_2001 GBV_ILN_2003 GBV_ILN_2004 GBV_ILN_2005 GBV_ILN_2006 GBV_ILN_2007 GBV_ILN_2008 GBV_ILN_2009 GBV_ILN_2010 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2015 GBV_ILN_2020 GBV_ILN_2021 GBV_ILN_2025 GBV_ILN_2026 GBV_ILN_2027 GBV_ILN_2031 GBV_ILN_2034 GBV_ILN_2037 GBV_ILN_2038 GBV_ILN_2039 GBV_ILN_2044 GBV_ILN_2048 GBV_ILN_2049 GBV_ILN_2050 GBV_ILN_2055 GBV_ILN_2056 GBV_ILN_2057 GBV_ILN_2059 GBV_ILN_2061 GBV_ILN_2064 GBV_ILN_2065 GBV_ILN_2068 GBV_ILN_2088 GBV_ILN_2093 GBV_ILN_2106 GBV_ILN_2107 GBV_ILN_2108 GBV_ILN_2110 GBV_ILN_2111 GBV_ILN_2112 GBV_ILN_2113 GBV_ILN_2118 GBV_ILN_2122 GBV_ILN_2129 GBV_ILN_2143 GBV_ILN_2144 GBV_ILN_2147 GBV_ILN_2148 GBV_ILN_2152 GBV_ILN_2153 GBV_ILN_2188 GBV_ILN_2190 GBV_ILN_2232 GBV_ILN_2336 GBV_ILN_2446 GBV_ILN_2470 GBV_ILN_2472 GBV_ILN_2507 GBV_ILN_2522 GBV_ILN_2548 GBV_ILN_4035 GBV_ILN_4037 GBV_ILN_4046 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4242 GBV_ILN_4246 GBV_ILN_4249 GBV_ILN_4251 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4326 GBV_ILN_4328 GBV_ILN_4333 GBV_ILN_4334 GBV_ILN_4335 GBV_ILN_4336 GBV_ILN_4338 GBV_ILN_4393 GBV_ILN_4700 AR 30 2021 7 04 03 4946-4956 |
| language |
English |
| source |
Enthalten in Journal of materials engineering and performance 30(2021), 7 vom: 04. März, Seite 4946-4956 volume:30 year:2021 number:7 day:04 month:03 pages:4946-4956 |
| sourceStr |
Enthalten in Journal of materials engineering and performance 30(2021), 7 vom: 04. März, Seite 4946-4956 volume:30 year:2021 number:7 day:04 month:03 pages:4946-4956 |
| format_phy_str_mv |
Article |
| institution |
findex.gbv.de |
| topic_facet |
3D printing hydroxyapatite in vitro bioactivity mechanical properties polylactic acid scaffolds Weibull distribution |
| isfreeaccess_bool |
false |
| container_title |
Journal of materials engineering and performance |
| authorswithroles_txt_mv |
Prakash, Chander @@aut@@ Singh, Gurminder @@aut@@ Singh, Sunpreet @@aut@@ Linda, W. L. @@aut@@ Zheng, H. Y. @@aut@@ Ramakrishna, Seeram @@aut@@ Narayan, Roger @@aut@@ |
| publishDateDaySort_date |
2021-03-04T00:00:00Z |
| hierarchy_top_id |
329975447 |
| id |
SPR044641001 |
| language_de |
englisch |
| fullrecord |
<?xml version="1.0" encoding="UTF-8"?><collection xmlns="http://www.loc.gov/MARC21/slim"><record><leader>01000caa a22002652 4500</leader><controlfield tag="001">SPR044641001</controlfield><controlfield tag="003">DE-627</controlfield><controlfield tag="005">20231014064640.0</controlfield><controlfield tag="007">cr uuu---uuuuu</controlfield><controlfield tag="008">210724s2021 xx |||||o 00| ||eng c</controlfield><datafield tag="024" ind1="7" ind2=" "><subfield code="a">10.1007/s11665-021-05566-x</subfield><subfield code="2">doi</subfield></datafield><datafield tag="035" ind1=" " ind2=" "><subfield code="a">(DE-627)SPR044641001</subfield></datafield><datafield tag="035" ind1=" " ind2=" "><subfield code="a">(SPR)s11665-021-05566-x-e</subfield></datafield><datafield tag="040" ind1=" " ind2=" "><subfield code="a">DE-627</subfield><subfield code="b">ger</subfield><subfield code="c">DE-627</subfield><subfield code="e">rakwb</subfield></datafield><datafield tag="041" ind1=" " ind2=" "><subfield code="a">eng</subfield></datafield><datafield tag="100" ind1="1" ind2=" "><subfield code="a">Prakash, Chander</subfield><subfield code="e">verfasserin</subfield><subfield code="4">aut</subfield></datafield><datafield tag="245" ind1="1" ind2="0"><subfield code="a">Mechanical Reliability and In Vitro Bioactivity of 3D-Printed Porous Polylactic Acid-Hydroxyapatite Scaffold</subfield></datafield><datafield tag="264" ind1=" " ind2="1"><subfield code="c">2021</subfield></datafield><datafield tag="336" ind1=" " ind2=" "><subfield code="a">Text</subfield><subfield code="b">txt</subfield><subfield code="2">rdacontent</subfield></datafield><datafield tag="337" ind1=" " ind2=" "><subfield code="a">Computermedien</subfield><subfield code="b">c</subfield><subfield code="2">rdamedia</subfield></datafield><datafield tag="338" ind1=" " ind2=" "><subfield code="a">Online-Ressource</subfield><subfield code="b">cr</subfield><subfield code="2">rdacarrier</subfield></datafield><datafield tag="500" ind1=" " ind2=" "><subfield code="a">© ASM International 2021. corrected publication 2021</subfield></datafield><datafield tag="520" ind1=" " ind2=" "><subfield code="a">Abstract The study aimed to investigate the mechanical reliability and in vitro bioactivity of the three-dimensional (3D) printed hydroxyapatite (HA) reinforced polylactic acid (PLA) porous scaffolds. The experiments have been performed to study the effect of HA wt.% in PLA matrix, infill density, and post-printing thermal-stimulus on the flexural and compressive strength. Next to this, the best combination of input parameters, in-response of the observed mechanical properties, was determined to print the test specimens for the analysis of reliability, through Weibull distribution. Further, the fracture morphology of the developed PLA/HA porous scaffolds has been investigated, using scanning electron microscopy, to observe the involved fracture mechanism. Moreover, the in vitro cell-culture with osteoblastic bone marrow mesenchymal stem cells-lines has been studied after 1, 3, and 7 days of seeding. The results of the study highlighted that the processing parameters have a strong impact on the mechanical properties of the 3D printed porous scaffolds. Further, the in vitro analysis showed excellent growth, proliferation, and differentiation of osteoplastic cells. Along with these, the result of the Weibull distribution advocated that the printed porous scaffolds are mechanically reliable. Overall, the present study unequivocally advocates that the 3D printed PLA/HA scaffold can be used for potential tissue engineering and biomedical applications.</subfield></datafield><datafield tag="650" ind1=" " ind2="4"><subfield code="a">3D printing</subfield><subfield code="7">(dpeaa)DE-He213</subfield></datafield><datafield tag="650" ind1=" " ind2="4"><subfield code="a">hydroxyapatite</subfield><subfield code="7">(dpeaa)DE-He213</subfield></datafield><datafield tag="650" ind1=" " ind2="4"><subfield code="a">in vitro bioactivity</subfield><subfield code="7">(dpeaa)DE-He213</subfield></datafield><datafield tag="650" ind1=" " ind2="4"><subfield code="a">mechanical properties</subfield><subfield code="7">(dpeaa)DE-He213</subfield></datafield><datafield tag="650" ind1=" " ind2="4"><subfield code="a">polylactic acid</subfield><subfield code="7">(dpeaa)DE-He213</subfield></datafield><datafield tag="650" ind1=" " ind2="4"><subfield code="a">scaffolds</subfield><subfield code="7">(dpeaa)DE-He213</subfield></datafield><datafield tag="650" ind1=" " ind2="4"><subfield code="a">Weibull distribution</subfield><subfield code="7">(dpeaa)DE-He213</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Singh, Gurminder</subfield><subfield code="4">aut</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Singh, Sunpreet</subfield><subfield code="0">(orcid)0000-0001-9592-4828</subfield><subfield code="4">aut</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Linda, W. L.</subfield><subfield code="4">aut</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Zheng, H. Y.</subfield><subfield code="4">aut</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Ramakrishna, Seeram</subfield><subfield code="4">aut</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Narayan, Roger</subfield><subfield code="4">aut</subfield></datafield><datafield tag="773" ind1="0" ind2="8"><subfield code="i">Enthalten in</subfield><subfield code="t">Journal of materials engineering and performance</subfield><subfield code="d">New York, NY : Springer, 1992</subfield><subfield code="g">30(2021), 7 vom: 04. März, Seite 4946-4956</subfield><subfield code="w">(DE-627)329975447</subfield><subfield code="w">(DE-600)2048384-3</subfield><subfield code="x">1544-1024</subfield><subfield code="7">nnns</subfield></datafield><datafield tag="773" ind1="1" ind2="8"><subfield code="g">volume:30</subfield><subfield code="g">year:2021</subfield><subfield code="g">number:7</subfield><subfield code="g">day:04</subfield><subfield code="g">month:03</subfield><subfield code="g">pages:4946-4956</subfield></datafield><datafield tag="856" ind1="4" ind2="0"><subfield code="u">https://dx.doi.org/10.1007/s11665-021-05566-x</subfield><subfield code="z">lizenzpflichtig</subfield><subfield code="3">Volltext</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_USEFLAG_A</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">SYSFLAG_A</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_SPRINGER</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_11</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_20</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_22</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_23</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_24</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_31</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_32</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_39</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_40</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_60</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_62</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_63</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_65</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_69</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_70</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_73</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_74</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_90</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_95</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_100</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_105</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_110</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_120</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_138</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_150</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_151</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_152</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_161</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_170</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_171</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_187</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_213</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_224</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_230</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_250</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_281</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_285</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_293</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_370</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_602</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_636</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_702</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_2001</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_2003</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_2004</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_2005</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_2006</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_2007</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_2008</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_2009</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_2010</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_2011</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_2014</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_2015</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_2020</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_2021</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_2025</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_2026</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_2027</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_2031</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_2034</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_2037</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_2038</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_2039</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_2044</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_2048</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_2049</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_2050</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_2055</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_2056</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_2057</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_2059</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_2061</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_2064</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_2065</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_2068</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_2088</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_2093</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_2106</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_2107</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_2108</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_2110</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_2111</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_2112</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_2113</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_2118</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_2122</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_2129</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_2143</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_2144</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_2147</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_2148</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_2152</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_2153</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_2188</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_2190</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_2232</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_2336</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_2446</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_2470</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_2472</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_2507</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_2522</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_2548</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_4035</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_4037</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_4046</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_4112</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_4125</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_4126</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_4242</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_4246</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_4249</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_4251</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_4305</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_4306</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_4307</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_4313</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_4322</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_4323</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_4324</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_4325</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_4326</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_4328</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_4333</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_4334</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_4335</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_4336</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_4338</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_4393</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_4700</subfield></datafield><datafield tag="951" ind1=" " ind2=" "><subfield code="a">AR</subfield></datafield><datafield tag="952" ind1=" " ind2=" "><subfield code="d">30</subfield><subfield code="j">2021</subfield><subfield code="e">7</subfield><subfield code="b">04</subfield><subfield code="c">03</subfield><subfield code="h">4946-4956</subfield></datafield></record></collection>
|
| author |
Prakash, Chander |
| spellingShingle |
Prakash, Chander misc 3D printing misc hydroxyapatite misc in vitro bioactivity misc mechanical properties misc polylactic acid misc scaffolds misc Weibull distribution Mechanical Reliability and In Vitro Bioactivity of 3D-Printed Porous Polylactic Acid-Hydroxyapatite Scaffold |
| authorStr |
Prakash, Chander |
| ppnlink_with_tag_str_mv |
@@773@@(DE-627)329975447 |
| format |
electronic Article |
| delete_txt_mv |
keep |
| author_role |
aut aut aut aut aut aut aut |
| collection |
springer |
| remote_str |
true |
| illustrated |
Not Illustrated |
| issn |
1544-1024 |
| topic_title |
Mechanical Reliability and In Vitro Bioactivity of 3D-Printed Porous Polylactic Acid-Hydroxyapatite Scaffold 3D printing (dpeaa)DE-He213 hydroxyapatite (dpeaa)DE-He213 in vitro bioactivity (dpeaa)DE-He213 mechanical properties (dpeaa)DE-He213 polylactic acid (dpeaa)DE-He213 scaffolds (dpeaa)DE-He213 Weibull distribution (dpeaa)DE-He213 |
| topic |
misc 3D printing misc hydroxyapatite misc in vitro bioactivity misc mechanical properties misc polylactic acid misc scaffolds misc Weibull distribution |
| topic_unstemmed |
misc 3D printing misc hydroxyapatite misc in vitro bioactivity misc mechanical properties misc polylactic acid misc scaffolds misc Weibull distribution |
| topic_browse |
misc 3D printing misc hydroxyapatite misc in vitro bioactivity misc mechanical properties misc polylactic acid misc scaffolds misc Weibull distribution |
| format_facet |
Elektronische Aufsätze Aufsätze Elektronische Ressource |
| format_main_str_mv |
Text Zeitschrift/Artikel |
| carriertype_str_mv |
cr |
| hierarchy_parent_title |
Journal of materials engineering and performance |
| hierarchy_parent_id |
329975447 |
| hierarchy_top_title |
Journal of materials engineering and performance |
| isfreeaccess_txt |
false |
| familylinks_str_mv |
(DE-627)329975447 (DE-600)2048384-3 |
| title |
Mechanical Reliability and In Vitro Bioactivity of 3D-Printed Porous Polylactic Acid-Hydroxyapatite Scaffold |
| ctrlnum |
(DE-627)SPR044641001 (SPR)s11665-021-05566-x-e |
| title_full |
Mechanical Reliability and In Vitro Bioactivity of 3D-Printed Porous Polylactic Acid-Hydroxyapatite Scaffold |
| author_sort |
Prakash, Chander |
| journal |
Journal of materials engineering and performance |
| journalStr |
Journal of materials engineering and performance |
| lang_code |
eng |
| isOA_bool |
false |
| recordtype |
marc |
| publishDateSort |
2021 |
| contenttype_str_mv |
txt |
| container_start_page |
4946 |
| author_browse |
Prakash, Chander Singh, Gurminder Singh, Sunpreet Linda, W. L. Zheng, H. Y. Ramakrishna, Seeram Narayan, Roger |
| container_volume |
30 |
| format_se |
Elektronische Aufsätze |
| author-letter |
Prakash, Chander |
| doi_str_mv |
10.1007/s11665-021-05566-x |
| normlink |
(ORCID)0000-0001-9592-4828 |
| normlink_prefix_str_mv |
(orcid)0000-0001-9592-4828 |
| title_sort |
mechanical reliability and in vitro bioactivity of 3d-printed porous polylactic acid-hydroxyapatite scaffold |
| title_auth |
Mechanical Reliability and In Vitro Bioactivity of 3D-Printed Porous Polylactic Acid-Hydroxyapatite Scaffold |
| abstract |
Abstract The study aimed to investigate the mechanical reliability and in vitro bioactivity of the three-dimensional (3D) printed hydroxyapatite (HA) reinforced polylactic acid (PLA) porous scaffolds. The experiments have been performed to study the effect of HA wt.% in PLA matrix, infill density, and post-printing thermal-stimulus on the flexural and compressive strength. Next to this, the best combination of input parameters, in-response of the observed mechanical properties, was determined to print the test specimens for the analysis of reliability, through Weibull distribution. Further, the fracture morphology of the developed PLA/HA porous scaffolds has been investigated, using scanning electron microscopy, to observe the involved fracture mechanism. Moreover, the in vitro cell-culture with osteoblastic bone marrow mesenchymal stem cells-lines has been studied after 1, 3, and 7 days of seeding. The results of the study highlighted that the processing parameters have a strong impact on the mechanical properties of the 3D printed porous scaffolds. Further, the in vitro analysis showed excellent growth, proliferation, and differentiation of osteoplastic cells. Along with these, the result of the Weibull distribution advocated that the printed porous scaffolds are mechanically reliable. Overall, the present study unequivocally advocates that the 3D printed PLA/HA scaffold can be used for potential tissue engineering and biomedical applications. © ASM International 2021. corrected publication 2021 |
| abstractGer |
Abstract The study aimed to investigate the mechanical reliability and in vitro bioactivity of the three-dimensional (3D) printed hydroxyapatite (HA) reinforced polylactic acid (PLA) porous scaffolds. The experiments have been performed to study the effect of HA wt.% in PLA matrix, infill density, and post-printing thermal-stimulus on the flexural and compressive strength. Next to this, the best combination of input parameters, in-response of the observed mechanical properties, was determined to print the test specimens for the analysis of reliability, through Weibull distribution. Further, the fracture morphology of the developed PLA/HA porous scaffolds has been investigated, using scanning electron microscopy, to observe the involved fracture mechanism. Moreover, the in vitro cell-culture with osteoblastic bone marrow mesenchymal stem cells-lines has been studied after 1, 3, and 7 days of seeding. The results of the study highlighted that the processing parameters have a strong impact on the mechanical properties of the 3D printed porous scaffolds. Further, the in vitro analysis showed excellent growth, proliferation, and differentiation of osteoplastic cells. Along with these, the result of the Weibull distribution advocated that the printed porous scaffolds are mechanically reliable. Overall, the present study unequivocally advocates that the 3D printed PLA/HA scaffold can be used for potential tissue engineering and biomedical applications. © ASM International 2021. corrected publication 2021 |
| abstract_unstemmed |
Abstract The study aimed to investigate the mechanical reliability and in vitro bioactivity of the three-dimensional (3D) printed hydroxyapatite (HA) reinforced polylactic acid (PLA) porous scaffolds. The experiments have been performed to study the effect of HA wt.% in PLA matrix, infill density, and post-printing thermal-stimulus on the flexural and compressive strength. Next to this, the best combination of input parameters, in-response of the observed mechanical properties, was determined to print the test specimens for the analysis of reliability, through Weibull distribution. Further, the fracture morphology of the developed PLA/HA porous scaffolds has been investigated, using scanning electron microscopy, to observe the involved fracture mechanism. Moreover, the in vitro cell-culture with osteoblastic bone marrow mesenchymal stem cells-lines has been studied after 1, 3, and 7 days of seeding. The results of the study highlighted that the processing parameters have a strong impact on the mechanical properties of the 3D printed porous scaffolds. Further, the in vitro analysis showed excellent growth, proliferation, and differentiation of osteoplastic cells. Along with these, the result of the Weibull distribution advocated that the printed porous scaffolds are mechanically reliable. Overall, the present study unequivocally advocates that the 3D printed PLA/HA scaffold can be used for potential tissue engineering and biomedical applications. © ASM International 2021. corrected publication 2021 |
| collection_details |
GBV_USEFLAG_A SYSFLAG_A GBV_SPRINGER GBV_ILN_11 GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_32 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_70 GBV_ILN_73 GBV_ILN_74 GBV_ILN_90 GBV_ILN_95 GBV_ILN_100 GBV_ILN_105 GBV_ILN_110 GBV_ILN_120 GBV_ILN_138 GBV_ILN_150 GBV_ILN_151 GBV_ILN_152 GBV_ILN_161 GBV_ILN_170 GBV_ILN_171 GBV_ILN_187 GBV_ILN_213 GBV_ILN_224 GBV_ILN_230 GBV_ILN_250 GBV_ILN_281 GBV_ILN_285 GBV_ILN_293 GBV_ILN_370 GBV_ILN_602 GBV_ILN_636 GBV_ILN_702 GBV_ILN_2001 GBV_ILN_2003 GBV_ILN_2004 GBV_ILN_2005 GBV_ILN_2006 GBV_ILN_2007 GBV_ILN_2008 GBV_ILN_2009 GBV_ILN_2010 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2015 GBV_ILN_2020 GBV_ILN_2021 GBV_ILN_2025 GBV_ILN_2026 GBV_ILN_2027 GBV_ILN_2031 GBV_ILN_2034 GBV_ILN_2037 GBV_ILN_2038 GBV_ILN_2039 GBV_ILN_2044 GBV_ILN_2048 GBV_ILN_2049 GBV_ILN_2050 GBV_ILN_2055 GBV_ILN_2056 GBV_ILN_2057 GBV_ILN_2059 GBV_ILN_2061 GBV_ILN_2064 GBV_ILN_2065 GBV_ILN_2068 GBV_ILN_2088 GBV_ILN_2093 GBV_ILN_2106 GBV_ILN_2107 GBV_ILN_2108 GBV_ILN_2110 GBV_ILN_2111 GBV_ILN_2112 GBV_ILN_2113 GBV_ILN_2118 GBV_ILN_2122 GBV_ILN_2129 GBV_ILN_2143 GBV_ILN_2144 GBV_ILN_2147 GBV_ILN_2148 GBV_ILN_2152 GBV_ILN_2153 GBV_ILN_2188 GBV_ILN_2190 GBV_ILN_2232 GBV_ILN_2336 GBV_ILN_2446 GBV_ILN_2470 GBV_ILN_2472 GBV_ILN_2507 GBV_ILN_2522 GBV_ILN_2548 GBV_ILN_4035 GBV_ILN_4037 GBV_ILN_4046 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4242 GBV_ILN_4246 GBV_ILN_4249 GBV_ILN_4251 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4326 GBV_ILN_4328 GBV_ILN_4333 GBV_ILN_4334 GBV_ILN_4335 GBV_ILN_4336 GBV_ILN_4338 GBV_ILN_4393 GBV_ILN_4700 |
| container_issue |
7 |
| title_short |
Mechanical Reliability and In Vitro Bioactivity of 3D-Printed Porous Polylactic Acid-Hydroxyapatite Scaffold |
| url |
https://dx.doi.org/10.1007/s11665-021-05566-x |
| remote_bool |
true |
| author2 |
Singh, Gurminder Singh, Sunpreet Linda, W. L. Zheng, H. Y. Ramakrishna, Seeram Narayan, Roger |
| author2Str |
Singh, Gurminder Singh, Sunpreet Linda, W. L. Zheng, H. Y. Ramakrishna, Seeram Narayan, Roger |
| ppnlink |
329975447 |
| mediatype_str_mv |
c |
| isOA_txt |
false |
| hochschulschrift_bool |
false |
| doi_str |
10.1007/s11665-021-05566-x |
| up_date |
2024-07-04T01:41:23.331Z |
| _version_ |
1803610785930280960 |
| fullrecord_marcxml |
<?xml version="1.0" encoding="UTF-8"?><collection xmlns="http://www.loc.gov/MARC21/slim"><record><leader>01000caa a22002652 4500</leader><controlfield tag="001">SPR044641001</controlfield><controlfield tag="003">DE-627</controlfield><controlfield tag="005">20231014064640.0</controlfield><controlfield tag="007">cr uuu---uuuuu</controlfield><controlfield tag="008">210724s2021 xx |||||o 00| ||eng c</controlfield><datafield tag="024" ind1="7" ind2=" "><subfield code="a">10.1007/s11665-021-05566-x</subfield><subfield code="2">doi</subfield></datafield><datafield tag="035" ind1=" " ind2=" "><subfield code="a">(DE-627)SPR044641001</subfield></datafield><datafield tag="035" ind1=" " ind2=" "><subfield code="a">(SPR)s11665-021-05566-x-e</subfield></datafield><datafield tag="040" ind1=" " ind2=" "><subfield code="a">DE-627</subfield><subfield code="b">ger</subfield><subfield code="c">DE-627</subfield><subfield code="e">rakwb</subfield></datafield><datafield tag="041" ind1=" " ind2=" "><subfield code="a">eng</subfield></datafield><datafield tag="100" ind1="1" ind2=" "><subfield code="a">Prakash, Chander</subfield><subfield code="e">verfasserin</subfield><subfield code="4">aut</subfield></datafield><datafield tag="245" ind1="1" ind2="0"><subfield code="a">Mechanical Reliability and In Vitro Bioactivity of 3D-Printed Porous Polylactic Acid-Hydroxyapatite Scaffold</subfield></datafield><datafield tag="264" ind1=" " ind2="1"><subfield code="c">2021</subfield></datafield><datafield tag="336" ind1=" " ind2=" "><subfield code="a">Text</subfield><subfield code="b">txt</subfield><subfield code="2">rdacontent</subfield></datafield><datafield tag="337" ind1=" " ind2=" "><subfield code="a">Computermedien</subfield><subfield code="b">c</subfield><subfield code="2">rdamedia</subfield></datafield><datafield tag="338" ind1=" " ind2=" "><subfield code="a">Online-Ressource</subfield><subfield code="b">cr</subfield><subfield code="2">rdacarrier</subfield></datafield><datafield tag="500" ind1=" " ind2=" "><subfield code="a">© ASM International 2021. corrected publication 2021</subfield></datafield><datafield tag="520" ind1=" " ind2=" "><subfield code="a">Abstract The study aimed to investigate the mechanical reliability and in vitro bioactivity of the three-dimensional (3D) printed hydroxyapatite (HA) reinforced polylactic acid (PLA) porous scaffolds. The experiments have been performed to study the effect of HA wt.% in PLA matrix, infill density, and post-printing thermal-stimulus on the flexural and compressive strength. Next to this, the best combination of input parameters, in-response of the observed mechanical properties, was determined to print the test specimens for the analysis of reliability, through Weibull distribution. Further, the fracture morphology of the developed PLA/HA porous scaffolds has been investigated, using scanning electron microscopy, to observe the involved fracture mechanism. Moreover, the in vitro cell-culture with osteoblastic bone marrow mesenchymal stem cells-lines has been studied after 1, 3, and 7 days of seeding. The results of the study highlighted that the processing parameters have a strong impact on the mechanical properties of the 3D printed porous scaffolds. Further, the in vitro analysis showed excellent growth, proliferation, and differentiation of osteoplastic cells. Along with these, the result of the Weibull distribution advocated that the printed porous scaffolds are mechanically reliable. Overall, the present study unequivocally advocates that the 3D printed PLA/HA scaffold can be used for potential tissue engineering and biomedical applications.</subfield></datafield><datafield tag="650" ind1=" " ind2="4"><subfield code="a">3D printing</subfield><subfield code="7">(dpeaa)DE-He213</subfield></datafield><datafield tag="650" ind1=" " ind2="4"><subfield code="a">hydroxyapatite</subfield><subfield code="7">(dpeaa)DE-He213</subfield></datafield><datafield tag="650" ind1=" " ind2="4"><subfield code="a">in vitro bioactivity</subfield><subfield code="7">(dpeaa)DE-He213</subfield></datafield><datafield tag="650" ind1=" " ind2="4"><subfield code="a">mechanical properties</subfield><subfield code="7">(dpeaa)DE-He213</subfield></datafield><datafield tag="650" ind1=" " ind2="4"><subfield code="a">polylactic acid</subfield><subfield code="7">(dpeaa)DE-He213</subfield></datafield><datafield tag="650" ind1=" " ind2="4"><subfield code="a">scaffolds</subfield><subfield code="7">(dpeaa)DE-He213</subfield></datafield><datafield tag="650" ind1=" " ind2="4"><subfield code="a">Weibull distribution</subfield><subfield code="7">(dpeaa)DE-He213</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Singh, Gurminder</subfield><subfield code="4">aut</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Singh, Sunpreet</subfield><subfield code="0">(orcid)0000-0001-9592-4828</subfield><subfield code="4">aut</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Linda, W. L.</subfield><subfield code="4">aut</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Zheng, H. Y.</subfield><subfield code="4">aut</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Ramakrishna, Seeram</subfield><subfield code="4">aut</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Narayan, Roger</subfield><subfield code="4">aut</subfield></datafield><datafield tag="773" ind1="0" ind2="8"><subfield code="i">Enthalten in</subfield><subfield code="t">Journal of materials engineering and performance</subfield><subfield code="d">New York, NY : Springer, 1992</subfield><subfield code="g">30(2021), 7 vom: 04. März, Seite 4946-4956</subfield><subfield code="w">(DE-627)329975447</subfield><subfield code="w">(DE-600)2048384-3</subfield><subfield code="x">1544-1024</subfield><subfield code="7">nnns</subfield></datafield><datafield tag="773" ind1="1" ind2="8"><subfield code="g">volume:30</subfield><subfield code="g">year:2021</subfield><subfield code="g">number:7</subfield><subfield code="g">day:04</subfield><subfield code="g">month:03</subfield><subfield code="g">pages:4946-4956</subfield></datafield><datafield tag="856" ind1="4" ind2="0"><subfield code="u">https://dx.doi.org/10.1007/s11665-021-05566-x</subfield><subfield code="z">lizenzpflichtig</subfield><subfield code="3">Volltext</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_USEFLAG_A</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">SYSFLAG_A</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_SPRINGER</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_11</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_20</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_22</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_23</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_24</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_31</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_32</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_39</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_40</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_60</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_62</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_63</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_65</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_69</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_70</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_73</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_74</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_90</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_95</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_100</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_105</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_110</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_120</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_138</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_150</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_151</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_152</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_161</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_170</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_171</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_187</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_213</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_224</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_230</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_250</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_281</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_285</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_293</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_370</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_602</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_636</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_702</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_2001</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_2003</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_2004</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_2005</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_2006</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_2007</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_2008</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_2009</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_2010</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_2011</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_2014</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_2015</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_2020</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_2021</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_2025</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_2026</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_2027</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_2031</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_2034</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_2037</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_2038</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_2039</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_2044</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_2048</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_2049</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_2050</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_2055</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_2056</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_2057</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_2059</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_2061</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_2064</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_2065</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_2068</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_2088</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_2093</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_2106</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_2107</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_2108</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_2110</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_2111</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_2112</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_2113</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_2118</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_2122</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_2129</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_2143</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_2144</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_2147</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_2148</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_2152</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_2153</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_2188</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_2190</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_2232</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_2336</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_2446</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_2470</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_2472</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_2507</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_2522</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_2548</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_4035</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_4037</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_4046</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_4112</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_4125</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_4126</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_4242</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_4246</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_4249</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_4251</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_4305</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_4306</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_4307</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_4313</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_4322</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_4323</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_4324</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_4325</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_4326</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_4328</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_4333</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_4334</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_4335</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_4336</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_4338</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_4393</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_4700</subfield></datafield><datafield tag="951" ind1=" " ind2=" "><subfield code="a">AR</subfield></datafield><datafield tag="952" ind1=" " ind2=" "><subfield code="d">30</subfield><subfield code="j">2021</subfield><subfield code="e">7</subfield><subfield code="b">04</subfield><subfield code="c">03</subfield><subfield code="h">4946-4956</subfield></datafield></record></collection>
|
| score |
7.4001675 |