Evaluation of antibacterial effect of silver nanoparticles paste with and without curcumin as intracanal medication
Background The purpose of the current study was to compare the antibacterial activity of silver nanoparticles AgNPs paste and silver nanoparticles AgNPs with curcumin paste as intracanal medications versus calcium hydroxide Ca(OH)2 paste. Thirty extracted, human teeth with single roots were decorona...
Ausführliche Beschreibung
Autor*in: |
Abdou, Soha Adel [verfasserIn] |
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E-Artikel |
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Englisch |
Erschienen: |
2022 |
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Anmerkung: |
© The Author(s) 2022 |
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Übergeordnetes Werk: |
Enthalten in: Bulletin of the National Research Centre - Berlin : Springer, 2018, 46(2022), 1 vom: 19. Feb. |
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Übergeordnetes Werk: |
volume:46 ; year:2022 ; number:1 ; day:19 ; month:02 |
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DOI / URN: |
10.1186/s42269-022-00723-1 |
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Katalog-ID: |
SPR046287574 |
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520 | |a Background The purpose of the current study was to compare the antibacterial activity of silver nanoparticles AgNPs paste and silver nanoparticles AgNPs with curcumin paste as intracanal medications versus calcium hydroxide Ca(OH)2 paste. Thirty extracted, human teeth with single roots were decoronated and mechanically prepared. After sterilization, roots were inoculated with Enterococcus faecalis for 10 days. Roots were separated into three groups in accordance to kind of intracanal medications used; Group A, silver nanoparticles AgNPs (Nanogate company, Cairo, Egypt). Group B, silver nanoparticles AgNPs with curcumin (Nanogate company, Cairo, Egypt). Group C, calcium hydroxide Ca(OH)2 (Metapaste, META BIOMED). First microbiological samples (S1) were collected from the canal, before insertion of intracanal medication. Intracanal medications were kept in root canals in all groups for 7 days; then second microbiological samples (S2) were collected from the canals after medicament removal. After the colony forming units CFUs have been counted, the data were statistically analyzed. Results In the three tested groups, the highest bacterial count was found in (S1), while the least bacterial count was found in (S2) with statistical significant difference between them. Conclusions The effect of AgNPs paste and AgNPs with curcumin paste was superior to Ca(OH)2 paste. AgNPs with curcumin paste had the best antibacterial effect. | ||
650 | 4 | |a Intracanal medication |7 (dpeaa)DE-He213 | |
650 | 4 | |a Curcumin |7 (dpeaa)DE-He213 | |
650 | 4 | |a Silver nanoparticles |7 (dpeaa)DE-He213 | |
650 | 4 | |a Calcium hydroxide |7 (dpeaa)DE-He213 | |
700 | 1 | |a Mohamed, Amira Ibrahim |4 aut | |
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10.1186/s42269-022-00723-1 doi (DE-627)SPR046287574 (SPR)s42269-022-00723-1-e DE-627 ger DE-627 rakwb eng Abdou, Soha Adel verfasserin aut Evaluation of antibacterial effect of silver nanoparticles paste with and without curcumin as intracanal medication 2022 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier © The Author(s) 2022 Background The purpose of the current study was to compare the antibacterial activity of silver nanoparticles AgNPs paste and silver nanoparticles AgNPs with curcumin paste as intracanal medications versus calcium hydroxide Ca(OH)2 paste. Thirty extracted, human teeth with single roots were decoronated and mechanically prepared. After sterilization, roots were inoculated with Enterococcus faecalis for 10 days. Roots were separated into three groups in accordance to kind of intracanal medications used; Group A, silver nanoparticles AgNPs (Nanogate company, Cairo, Egypt). Group B, silver nanoparticles AgNPs with curcumin (Nanogate company, Cairo, Egypt). Group C, calcium hydroxide Ca(OH)2 (Metapaste, META BIOMED). First microbiological samples (S1) were collected from the canal, before insertion of intracanal medication. Intracanal medications were kept in root canals in all groups for 7 days; then second microbiological samples (S2) were collected from the canals after medicament removal. After the colony forming units CFUs have been counted, the data were statistically analyzed. Results In the three tested groups, the highest bacterial count was found in (S1), while the least bacterial count was found in (S2) with statistical significant difference between them. Conclusions The effect of AgNPs paste and AgNPs with curcumin paste was superior to Ca(OH)2 paste. AgNPs with curcumin paste had the best antibacterial effect. Intracanal medication (dpeaa)DE-He213 Curcumin (dpeaa)DE-He213 Silver nanoparticles (dpeaa)DE-He213 Calcium hydroxide (dpeaa)DE-He213 Mohamed, Amira Ibrahim aut Enthalten in Bulletin of the National Research Centre Berlin : Springer, 2018 46(2022), 1 vom: 19. Feb. (DE-627)1035877007 (DE-600)2946659-3 2522-8307 nnns volume:46 year:2022 number:1 day:19 month:02 https://dx.doi.org/10.1186/s42269-022-00723-1 kostenfrei Volltext GBV_USEFLAG_A SYSFLAG_A GBV_SPRINGER GBV_ILN_11 GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_70 GBV_ILN_73 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_171 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_370 GBV_ILN_602 GBV_ILN_2005 GBV_ILN_2009 GBV_ILN_2014 GBV_ILN_2055 GBV_ILN_2111 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4335 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 46 2022 1 19 02 |
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10.1186/s42269-022-00723-1 doi (DE-627)SPR046287574 (SPR)s42269-022-00723-1-e DE-627 ger DE-627 rakwb eng Abdou, Soha Adel verfasserin aut Evaluation of antibacterial effect of silver nanoparticles paste with and without curcumin as intracanal medication 2022 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier © The Author(s) 2022 Background The purpose of the current study was to compare the antibacterial activity of silver nanoparticles AgNPs paste and silver nanoparticles AgNPs with curcumin paste as intracanal medications versus calcium hydroxide Ca(OH)2 paste. Thirty extracted, human teeth with single roots were decoronated and mechanically prepared. After sterilization, roots were inoculated with Enterococcus faecalis for 10 days. Roots were separated into three groups in accordance to kind of intracanal medications used; Group A, silver nanoparticles AgNPs (Nanogate company, Cairo, Egypt). Group B, silver nanoparticles AgNPs with curcumin (Nanogate company, Cairo, Egypt). Group C, calcium hydroxide Ca(OH)2 (Metapaste, META BIOMED). First microbiological samples (S1) were collected from the canal, before insertion of intracanal medication. Intracanal medications were kept in root canals in all groups for 7 days; then second microbiological samples (S2) were collected from the canals after medicament removal. After the colony forming units CFUs have been counted, the data were statistically analyzed. Results In the three tested groups, the highest bacterial count was found in (S1), while the least bacterial count was found in (S2) with statistical significant difference between them. Conclusions The effect of AgNPs paste and AgNPs with curcumin paste was superior to Ca(OH)2 paste. AgNPs with curcumin paste had the best antibacterial effect. Intracanal medication (dpeaa)DE-He213 Curcumin (dpeaa)DE-He213 Silver nanoparticles (dpeaa)DE-He213 Calcium hydroxide (dpeaa)DE-He213 Mohamed, Amira Ibrahim aut Enthalten in Bulletin of the National Research Centre Berlin : Springer, 2018 46(2022), 1 vom: 19. Feb. (DE-627)1035877007 (DE-600)2946659-3 2522-8307 nnns volume:46 year:2022 number:1 day:19 month:02 https://dx.doi.org/10.1186/s42269-022-00723-1 kostenfrei Volltext GBV_USEFLAG_A SYSFLAG_A GBV_SPRINGER GBV_ILN_11 GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_70 GBV_ILN_73 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_171 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_370 GBV_ILN_602 GBV_ILN_2005 GBV_ILN_2009 GBV_ILN_2014 GBV_ILN_2055 GBV_ILN_2111 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4335 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 46 2022 1 19 02 |
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10.1186/s42269-022-00723-1 doi (DE-627)SPR046287574 (SPR)s42269-022-00723-1-e DE-627 ger DE-627 rakwb eng Abdou, Soha Adel verfasserin aut Evaluation of antibacterial effect of silver nanoparticles paste with and without curcumin as intracanal medication 2022 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier © The Author(s) 2022 Background The purpose of the current study was to compare the antibacterial activity of silver nanoparticles AgNPs paste and silver nanoparticles AgNPs with curcumin paste as intracanal medications versus calcium hydroxide Ca(OH)2 paste. Thirty extracted, human teeth with single roots were decoronated and mechanically prepared. After sterilization, roots were inoculated with Enterococcus faecalis for 10 days. Roots were separated into three groups in accordance to kind of intracanal medications used; Group A, silver nanoparticles AgNPs (Nanogate company, Cairo, Egypt). Group B, silver nanoparticles AgNPs with curcumin (Nanogate company, Cairo, Egypt). Group C, calcium hydroxide Ca(OH)2 (Metapaste, META BIOMED). First microbiological samples (S1) were collected from the canal, before insertion of intracanal medication. Intracanal medications were kept in root canals in all groups for 7 days; then second microbiological samples (S2) were collected from the canals after medicament removal. After the colony forming units CFUs have been counted, the data were statistically analyzed. Results In the three tested groups, the highest bacterial count was found in (S1), while the least bacterial count was found in (S2) with statistical significant difference between them. Conclusions The effect of AgNPs paste and AgNPs with curcumin paste was superior to Ca(OH)2 paste. AgNPs with curcumin paste had the best antibacterial effect. Intracanal medication (dpeaa)DE-He213 Curcumin (dpeaa)DE-He213 Silver nanoparticles (dpeaa)DE-He213 Calcium hydroxide (dpeaa)DE-He213 Mohamed, Amira Ibrahim aut Enthalten in Bulletin of the National Research Centre Berlin : Springer, 2018 46(2022), 1 vom: 19. Feb. (DE-627)1035877007 (DE-600)2946659-3 2522-8307 nnns volume:46 year:2022 number:1 day:19 month:02 https://dx.doi.org/10.1186/s42269-022-00723-1 kostenfrei Volltext GBV_USEFLAG_A SYSFLAG_A GBV_SPRINGER GBV_ILN_11 GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_70 GBV_ILN_73 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_171 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_370 GBV_ILN_602 GBV_ILN_2005 GBV_ILN_2009 GBV_ILN_2014 GBV_ILN_2055 GBV_ILN_2111 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4335 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 46 2022 1 19 02 |
allfieldsGer |
10.1186/s42269-022-00723-1 doi (DE-627)SPR046287574 (SPR)s42269-022-00723-1-e DE-627 ger DE-627 rakwb eng Abdou, Soha Adel verfasserin aut Evaluation of antibacterial effect of silver nanoparticles paste with and without curcumin as intracanal medication 2022 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier © The Author(s) 2022 Background The purpose of the current study was to compare the antibacterial activity of silver nanoparticles AgNPs paste and silver nanoparticles AgNPs with curcumin paste as intracanal medications versus calcium hydroxide Ca(OH)2 paste. Thirty extracted, human teeth with single roots were decoronated and mechanically prepared. After sterilization, roots were inoculated with Enterococcus faecalis for 10 days. Roots were separated into three groups in accordance to kind of intracanal medications used; Group A, silver nanoparticles AgNPs (Nanogate company, Cairo, Egypt). Group B, silver nanoparticles AgNPs with curcumin (Nanogate company, Cairo, Egypt). Group C, calcium hydroxide Ca(OH)2 (Metapaste, META BIOMED). First microbiological samples (S1) were collected from the canal, before insertion of intracanal medication. Intracanal medications were kept in root canals in all groups for 7 days; then second microbiological samples (S2) were collected from the canals after medicament removal. After the colony forming units CFUs have been counted, the data were statistically analyzed. Results In the three tested groups, the highest bacterial count was found in (S1), while the least bacterial count was found in (S2) with statistical significant difference between them. Conclusions The effect of AgNPs paste and AgNPs with curcumin paste was superior to Ca(OH)2 paste. AgNPs with curcumin paste had the best antibacterial effect. Intracanal medication (dpeaa)DE-He213 Curcumin (dpeaa)DE-He213 Silver nanoparticles (dpeaa)DE-He213 Calcium hydroxide (dpeaa)DE-He213 Mohamed, Amira Ibrahim aut Enthalten in Bulletin of the National Research Centre Berlin : Springer, 2018 46(2022), 1 vom: 19. Feb. (DE-627)1035877007 (DE-600)2946659-3 2522-8307 nnns volume:46 year:2022 number:1 day:19 month:02 https://dx.doi.org/10.1186/s42269-022-00723-1 kostenfrei Volltext GBV_USEFLAG_A SYSFLAG_A GBV_SPRINGER GBV_ILN_11 GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_70 GBV_ILN_73 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_171 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_370 GBV_ILN_602 GBV_ILN_2005 GBV_ILN_2009 GBV_ILN_2014 GBV_ILN_2055 GBV_ILN_2111 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4335 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 46 2022 1 19 02 |
allfieldsSound |
10.1186/s42269-022-00723-1 doi (DE-627)SPR046287574 (SPR)s42269-022-00723-1-e DE-627 ger DE-627 rakwb eng Abdou, Soha Adel verfasserin aut Evaluation of antibacterial effect of silver nanoparticles paste with and without curcumin as intracanal medication 2022 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier © The Author(s) 2022 Background The purpose of the current study was to compare the antibacterial activity of silver nanoparticles AgNPs paste and silver nanoparticles AgNPs with curcumin paste as intracanal medications versus calcium hydroxide Ca(OH)2 paste. Thirty extracted, human teeth with single roots were decoronated and mechanically prepared. After sterilization, roots were inoculated with Enterococcus faecalis for 10 days. Roots were separated into three groups in accordance to kind of intracanal medications used; Group A, silver nanoparticles AgNPs (Nanogate company, Cairo, Egypt). Group B, silver nanoparticles AgNPs with curcumin (Nanogate company, Cairo, Egypt). Group C, calcium hydroxide Ca(OH)2 (Metapaste, META BIOMED). First microbiological samples (S1) were collected from the canal, before insertion of intracanal medication. Intracanal medications were kept in root canals in all groups for 7 days; then second microbiological samples (S2) were collected from the canals after medicament removal. After the colony forming units CFUs have been counted, the data were statistically analyzed. Results In the three tested groups, the highest bacterial count was found in (S1), while the least bacterial count was found in (S2) with statistical significant difference between them. Conclusions The effect of AgNPs paste and AgNPs with curcumin paste was superior to Ca(OH)2 paste. AgNPs with curcumin paste had the best antibacterial effect. Intracanal medication (dpeaa)DE-He213 Curcumin (dpeaa)DE-He213 Silver nanoparticles (dpeaa)DE-He213 Calcium hydroxide (dpeaa)DE-He213 Mohamed, Amira Ibrahim aut Enthalten in Bulletin of the National Research Centre Berlin : Springer, 2018 46(2022), 1 vom: 19. Feb. (DE-627)1035877007 (DE-600)2946659-3 2522-8307 nnns volume:46 year:2022 number:1 day:19 month:02 https://dx.doi.org/10.1186/s42269-022-00723-1 kostenfrei Volltext GBV_USEFLAG_A SYSFLAG_A GBV_SPRINGER GBV_ILN_11 GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_70 GBV_ILN_73 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_171 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_370 GBV_ILN_602 GBV_ILN_2005 GBV_ILN_2009 GBV_ILN_2014 GBV_ILN_2055 GBV_ILN_2111 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4335 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 46 2022 1 19 02 |
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Thirty extracted, human teeth with single roots were decoronated and mechanically prepared. After sterilization, roots were inoculated with Enterococcus faecalis for 10 days. Roots were separated into three groups in accordance to kind of intracanal medications used; Group A, silver nanoparticles AgNPs (Nanogate company, Cairo, Egypt). Group B, silver nanoparticles AgNPs with curcumin (Nanogate company, Cairo, Egypt). Group C, calcium hydroxide Ca(OH)2 (Metapaste, META BIOMED). First microbiological samples (S1) were collected from the canal, before insertion of intracanal medication. Intracanal medications were kept in root canals in all groups for 7 days; then second microbiological samples (S2) were collected from the canals after medicament removal. After the colony forming units CFUs have been counted, the data were statistically analyzed. Results In the three tested groups, the highest bacterial count was found in (S1), while the least bacterial count was found in (S2) with statistical significant difference between them. Conclusions The effect of AgNPs paste and AgNPs with curcumin paste was superior to Ca(OH)2 paste. 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Abdou, Soha Adel |
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Evaluation of antibacterial effect of silver nanoparticles paste with and without curcumin as intracanal medication Intracanal medication (dpeaa)DE-He213 Curcumin (dpeaa)DE-He213 Silver nanoparticles (dpeaa)DE-He213 Calcium hydroxide (dpeaa)DE-He213 |
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evaluation of antibacterial effect of silver nanoparticles paste with and without curcumin as intracanal medication |
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Evaluation of antibacterial effect of silver nanoparticles paste with and without curcumin as intracanal medication |
abstract |
Background The purpose of the current study was to compare the antibacterial activity of silver nanoparticles AgNPs paste and silver nanoparticles AgNPs with curcumin paste as intracanal medications versus calcium hydroxide Ca(OH)2 paste. Thirty extracted, human teeth with single roots were decoronated and mechanically prepared. After sterilization, roots were inoculated with Enterococcus faecalis for 10 days. Roots were separated into three groups in accordance to kind of intracanal medications used; Group A, silver nanoparticles AgNPs (Nanogate company, Cairo, Egypt). Group B, silver nanoparticles AgNPs with curcumin (Nanogate company, Cairo, Egypt). Group C, calcium hydroxide Ca(OH)2 (Metapaste, META BIOMED). First microbiological samples (S1) were collected from the canal, before insertion of intracanal medication. Intracanal medications were kept in root canals in all groups for 7 days; then second microbiological samples (S2) were collected from the canals after medicament removal. After the colony forming units CFUs have been counted, the data were statistically analyzed. Results In the three tested groups, the highest bacterial count was found in (S1), while the least bacterial count was found in (S2) with statistical significant difference between them. Conclusions The effect of AgNPs paste and AgNPs with curcumin paste was superior to Ca(OH)2 paste. AgNPs with curcumin paste had the best antibacterial effect. © The Author(s) 2022 |
abstractGer |
Background The purpose of the current study was to compare the antibacterial activity of silver nanoparticles AgNPs paste and silver nanoparticles AgNPs with curcumin paste as intracanal medications versus calcium hydroxide Ca(OH)2 paste. Thirty extracted, human teeth with single roots were decoronated and mechanically prepared. After sterilization, roots were inoculated with Enterococcus faecalis for 10 days. Roots were separated into three groups in accordance to kind of intracanal medications used; Group A, silver nanoparticles AgNPs (Nanogate company, Cairo, Egypt). Group B, silver nanoparticles AgNPs with curcumin (Nanogate company, Cairo, Egypt). Group C, calcium hydroxide Ca(OH)2 (Metapaste, META BIOMED). First microbiological samples (S1) were collected from the canal, before insertion of intracanal medication. Intracanal medications were kept in root canals in all groups for 7 days; then second microbiological samples (S2) were collected from the canals after medicament removal. After the colony forming units CFUs have been counted, the data were statistically analyzed. Results In the three tested groups, the highest bacterial count was found in (S1), while the least bacterial count was found in (S2) with statistical significant difference between them. Conclusions The effect of AgNPs paste and AgNPs with curcumin paste was superior to Ca(OH)2 paste. AgNPs with curcumin paste had the best antibacterial effect. © The Author(s) 2022 |
abstract_unstemmed |
Background The purpose of the current study was to compare the antibacterial activity of silver nanoparticles AgNPs paste and silver nanoparticles AgNPs with curcumin paste as intracanal medications versus calcium hydroxide Ca(OH)2 paste. Thirty extracted, human teeth with single roots were decoronated and mechanically prepared. After sterilization, roots were inoculated with Enterococcus faecalis for 10 days. Roots were separated into three groups in accordance to kind of intracanal medications used; Group A, silver nanoparticles AgNPs (Nanogate company, Cairo, Egypt). Group B, silver nanoparticles AgNPs with curcumin (Nanogate company, Cairo, Egypt). Group C, calcium hydroxide Ca(OH)2 (Metapaste, META BIOMED). First microbiological samples (S1) were collected from the canal, before insertion of intracanal medication. Intracanal medications were kept in root canals in all groups for 7 days; then second microbiological samples (S2) were collected from the canals after medicament removal. After the colony forming units CFUs have been counted, the data were statistically analyzed. Results In the three tested groups, the highest bacterial count was found in (S1), while the least bacterial count was found in (S2) with statistical significant difference between them. Conclusions The effect of AgNPs paste and AgNPs with curcumin paste was superior to Ca(OH)2 paste. AgNPs with curcumin paste had the best antibacterial effect. © The Author(s) 2022 |
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Evaluation of antibacterial effect of silver nanoparticles paste with and without curcumin as intracanal medication |
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7.3980484 |