Development and Challenge of Fluorescent Probes for Bioimaging Applications: From Visualization to Diagnosis

Abstract Fluorescent probes have been used widely in bioimaging, including biological substance detection, cell imaging, in vivo biochemical reaction process tracking, and disease biomarker monitoring, and have gradually occupied an indispensable position. Compared with traditional biological imagin...
Ausführliche Beschreibung

Gespeichert in:

Autor*in:	Li, Yanchen [verfasserIn] Chen, Qinhua Pan, Xiaoyan Lu, Wen Zhang, Jie

Format:	E-Artikel
Sprache:	Englisch

Erschienen:	2022

Schlagwörter:	Fluorescent probe Fluorophore structure UV–vis fluorescent probe Bioimaging application

Anmerkung:	© The Author(s), under exclusive licence to Springer Nature Switzerland AG 2022

Übergeordnetes Werk:	Enthalten in: Topics in current chemistry - [Cham] : Springer International Publishing, 2016, 380(2022), 4 vom: 12. Apr.
Übergeordnetes Werk:	volume:380 ; year:2022 ; number:4 ; day:12 ; month:04

Links:	Volltext

DOI / URN:	10.1007/s41061-022-00376-8

Katalog-ID:	SPR046747990

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allfields	10.1007/s41061-022-00376-8 doi (DE-627)SPR046747990 (SPR)s41061-022-00376-8-e DE-627 ger DE-627 rakwb eng Li, Yanchen verfasserin aut Development and Challenge of Fluorescent Probes for Bioimaging Applications: From Visualization to Diagnosis 2022 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier © The Author(s), under exclusive licence to Springer Nature Switzerland AG 2022 Abstract Fluorescent probes have been used widely in bioimaging, including biological substance detection, cell imaging, in vivo biochemical reaction process tracking, and disease biomarker monitoring, and have gradually occupied an indispensable position. Compared with traditional biological imaging technologies, such as positron emission tomography (PET) and nuclear magnetic resonance imaging (MRI), the attractive advantages of fluorescent probes, such as real-time imaging, in-depth visualization, and less damage to biological samples, have made them increasingly popular. Among them, ultraviolet–visible (UV–vis) fluorescent probes still occupy the mainstream in the field of fluorescent probes due to the advantages of available structure, simple synthesis, strong versatility, and wide application. In recent years, fluorescent probes have become an indispensable tool for bioimaging and have greatly promoted the development of diagnostics. In this review, we focus on the structure, design strategies, advantages, representative probes and latest discoveries in application fields of UV–visible fluorescent probes developed in the past 3–5 years based on several fluorophores. We look forward to future development trends of fluorescent probes from the perspective of bioimaging and diagnostics. This comprehensive review may facilitate the development of more powerful fluorescent sensors for broad and exciting applications in the future. Fluorescent probe (dpeaa)DE-He213 Fluorophore structure (dpeaa)DE-He213 UV–vis fluorescent probe (dpeaa)DE-He213 Bioimaging application (dpeaa)DE-He213 Chen, Qinhua aut Pan, Xiaoyan aut Lu, Wen aut Zhang, Jie (orcid)0000-0003-2727-8806 aut Enthalten in Topics in current chemistry [Cham] : Springer International Publishing, 2016 380(2022), 4 vom: 12. Apr. (DE-627)848753445 (DE-600)2848485-X 2364-8961 nnns volume:380 year:2022 number:4 day:12 month:04 https://dx.doi.org/10.1007/s41061-022-00376-8 lizenzpflichtig Volltext GBV_USEFLAG_A SYSFLAG_A GBV_SPRINGER SSG-OLC-PHA GBV_ILN_11 GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_32 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_70 GBV_ILN_73 GBV_ILN_74 GBV_ILN_90 GBV_ILN_95 GBV_ILN_100 GBV_ILN_101 GBV_ILN_105 GBV_ILN_110 GBV_ILN_120 GBV_ILN_138 GBV_ILN_150 GBV_ILN_151 GBV_ILN_152 GBV_ILN_161 GBV_ILN_170 GBV_ILN_171 GBV_ILN_187 GBV_ILN_213 GBV_ILN_224 GBV_ILN_230 GBV_ILN_250 GBV_ILN_281 GBV_ILN_285 GBV_ILN_293 GBV_ILN_370 GBV_ILN_602 GBV_ILN_636 GBV_ILN_702 GBV_ILN_2001 GBV_ILN_2003 GBV_ILN_2004 GBV_ILN_2005 GBV_ILN_2006 GBV_ILN_2007 GBV_ILN_2008 GBV_ILN_2009 GBV_ILN_2010 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2015 GBV_ILN_2020 GBV_ILN_2021 GBV_ILN_2025 GBV_ILN_2026 GBV_ILN_2027 GBV_ILN_2031 GBV_ILN_2034 GBV_ILN_2037 GBV_ILN_2038 GBV_ILN_2039 GBV_ILN_2044 GBV_ILN_2048 GBV_ILN_2049 GBV_ILN_2050 GBV_ILN_2055 GBV_ILN_2056 GBV_ILN_2057 GBV_ILN_2059 GBV_ILN_2061 GBV_ILN_2064 GBV_ILN_2065 GBV_ILN_2068 GBV_ILN_2088 GBV_ILN_2093 GBV_ILN_2106 GBV_ILN_2107 GBV_ILN_2108 GBV_ILN_2110 GBV_ILN_2111 GBV_ILN_2112 GBV_ILN_2113 GBV_ILN_2118 GBV_ILN_2122 GBV_ILN_2129 GBV_ILN_2143 GBV_ILN_2144 GBV_ILN_2147 GBV_ILN_2148 GBV_ILN_2152 GBV_ILN_2153 GBV_ILN_2188 GBV_ILN_2190 GBV_ILN_2232 GBV_ILN_2336 GBV_ILN_2446 GBV_ILN_2470 GBV_ILN_2472 GBV_ILN_2507 GBV_ILN_2522 GBV_ILN_2548 GBV_ILN_4035 GBV_ILN_4037 GBV_ILN_4046 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4242 GBV_ILN_4246 GBV_ILN_4249 GBV_ILN_4251 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4326 GBV_ILN_4328 GBV_ILN_4333 GBV_ILN_4334 GBV_ILN_4335 GBV_ILN_4336 GBV_ILN_4338 GBV_ILN_4393 GBV_ILN_4700 AR 380 2022 4 12 04
spelling	10.1007/s41061-022-00376-8 doi (DE-627)SPR046747990 (SPR)s41061-022-00376-8-e DE-627 ger DE-627 rakwb eng Li, Yanchen verfasserin aut Development and Challenge of Fluorescent Probes for Bioimaging Applications: From Visualization to Diagnosis 2022 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier © The Author(s), under exclusive licence to Springer Nature Switzerland AG 2022 Abstract Fluorescent probes have been used widely in bioimaging, including biological substance detection, cell imaging, in vivo biochemical reaction process tracking, and disease biomarker monitoring, and have gradually occupied an indispensable position. Compared with traditional biological imaging technologies, such as positron emission tomography (PET) and nuclear magnetic resonance imaging (MRI), the attractive advantages of fluorescent probes, such as real-time imaging, in-depth visualization, and less damage to biological samples, have made them increasingly popular. Among them, ultraviolet–visible (UV–vis) fluorescent probes still occupy the mainstream in the field of fluorescent probes due to the advantages of available structure, simple synthesis, strong versatility, and wide application. In recent years, fluorescent probes have become an indispensable tool for bioimaging and have greatly promoted the development of diagnostics. In this review, we focus on the structure, design strategies, advantages, representative probes and latest discoveries in application fields of UV–visible fluorescent probes developed in the past 3–5 years based on several fluorophores. We look forward to future development trends of fluorescent probes from the perspective of bioimaging and diagnostics. This comprehensive review may facilitate the development of more powerful fluorescent sensors for broad and exciting applications in the future. Fluorescent probe (dpeaa)DE-He213 Fluorophore structure (dpeaa)DE-He213 UV–vis fluorescent probe (dpeaa)DE-He213 Bioimaging application (dpeaa)DE-He213 Chen, Qinhua aut Pan, Xiaoyan aut Lu, Wen aut Zhang, Jie (orcid)0000-0003-2727-8806 aut Enthalten in Topics in current chemistry [Cham] : Springer International Publishing, 2016 380(2022), 4 vom: 12. Apr. (DE-627)848753445 (DE-600)2848485-X 2364-8961 nnns volume:380 year:2022 number:4 day:12 month:04 https://dx.doi.org/10.1007/s41061-022-00376-8 lizenzpflichtig Volltext GBV_USEFLAG_A SYSFLAG_A GBV_SPRINGER SSG-OLC-PHA GBV_ILN_11 GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_32 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_70 GBV_ILN_73 GBV_ILN_74 GBV_ILN_90 GBV_ILN_95 GBV_ILN_100 GBV_ILN_101 GBV_ILN_105 GBV_ILN_110 GBV_ILN_120 GBV_ILN_138 GBV_ILN_150 GBV_ILN_151 GBV_ILN_152 GBV_ILN_161 GBV_ILN_170 GBV_ILN_171 GBV_ILN_187 GBV_ILN_213 GBV_ILN_224 GBV_ILN_230 GBV_ILN_250 GBV_ILN_281 GBV_ILN_285 GBV_ILN_293 GBV_ILN_370 GBV_ILN_602 GBV_ILN_636 GBV_ILN_702 GBV_ILN_2001 GBV_ILN_2003 GBV_ILN_2004 GBV_ILN_2005 GBV_ILN_2006 GBV_ILN_2007 GBV_ILN_2008 GBV_ILN_2009 GBV_ILN_2010 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2015 GBV_ILN_2020 GBV_ILN_2021 GBV_ILN_2025 GBV_ILN_2026 GBV_ILN_2027 GBV_ILN_2031 GBV_ILN_2034 GBV_ILN_2037 GBV_ILN_2038 GBV_ILN_2039 GBV_ILN_2044 GBV_ILN_2048 GBV_ILN_2049 GBV_ILN_2050 GBV_ILN_2055 GBV_ILN_2056 GBV_ILN_2057 GBV_ILN_2059 GBV_ILN_2061 GBV_ILN_2064 GBV_ILN_2065 GBV_ILN_2068 GBV_ILN_2088 GBV_ILN_2093 GBV_ILN_2106 GBV_ILN_2107 GBV_ILN_2108 GBV_ILN_2110 GBV_ILN_2111 GBV_ILN_2112 GBV_ILN_2113 GBV_ILN_2118 GBV_ILN_2122 GBV_ILN_2129 GBV_ILN_2143 GBV_ILN_2144 GBV_ILN_2147 GBV_ILN_2148 GBV_ILN_2152 GBV_ILN_2153 GBV_ILN_2188 GBV_ILN_2190 GBV_ILN_2232 GBV_ILN_2336 GBV_ILN_2446 GBV_ILN_2470 GBV_ILN_2472 GBV_ILN_2507 GBV_ILN_2522 GBV_ILN_2548 GBV_ILN_4035 GBV_ILN_4037 GBV_ILN_4046 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4242 GBV_ILN_4246 GBV_ILN_4249 GBV_ILN_4251 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4326 GBV_ILN_4328 GBV_ILN_4333 GBV_ILN_4334 GBV_ILN_4335 GBV_ILN_4336 GBV_ILN_4338 GBV_ILN_4393 GBV_ILN_4700 AR 380 2022 4 12 04
allfields_unstemmed	10.1007/s41061-022-00376-8 doi (DE-627)SPR046747990 (SPR)s41061-022-00376-8-e DE-627 ger DE-627 rakwb eng Li, Yanchen verfasserin aut Development and Challenge of Fluorescent Probes for Bioimaging Applications: From Visualization to Diagnosis 2022 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier © The Author(s), under exclusive licence to Springer Nature Switzerland AG 2022 Abstract Fluorescent probes have been used widely in bioimaging, including biological substance detection, cell imaging, in vivo biochemical reaction process tracking, and disease biomarker monitoring, and have gradually occupied an indispensable position. Compared with traditional biological imaging technologies, such as positron emission tomography (PET) and nuclear magnetic resonance imaging (MRI), the attractive advantages of fluorescent probes, such as real-time imaging, in-depth visualization, and less damage to biological samples, have made them increasingly popular. Among them, ultraviolet–visible (UV–vis) fluorescent probes still occupy the mainstream in the field of fluorescent probes due to the advantages of available structure, simple synthesis, strong versatility, and wide application. In recent years, fluorescent probes have become an indispensable tool for bioimaging and have greatly promoted the development of diagnostics. In this review, we focus on the structure, design strategies, advantages, representative probes and latest discoveries in application fields of UV–visible fluorescent probes developed in the past 3–5 years based on several fluorophores. We look forward to future development trends of fluorescent probes from the perspective of bioimaging and diagnostics. This comprehensive review may facilitate the development of more powerful fluorescent sensors for broad and exciting applications in the future. Fluorescent probe (dpeaa)DE-He213 Fluorophore structure (dpeaa)DE-He213 UV–vis fluorescent probe (dpeaa)DE-He213 Bioimaging application (dpeaa)DE-He213 Chen, Qinhua aut Pan, Xiaoyan aut Lu, Wen aut Zhang, Jie (orcid)0000-0003-2727-8806 aut Enthalten in Topics in current chemistry [Cham] : Springer International Publishing, 2016 380(2022), 4 vom: 12. Apr. (DE-627)848753445 (DE-600)2848485-X 2364-8961 nnns volume:380 year:2022 number:4 day:12 month:04 https://dx.doi.org/10.1007/s41061-022-00376-8 lizenzpflichtig Volltext GBV_USEFLAG_A SYSFLAG_A GBV_SPRINGER SSG-OLC-PHA GBV_ILN_11 GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_32 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_70 GBV_ILN_73 GBV_ILN_74 GBV_ILN_90 GBV_ILN_95 GBV_ILN_100 GBV_ILN_101 GBV_ILN_105 GBV_ILN_110 GBV_ILN_120 GBV_ILN_138 GBV_ILN_150 GBV_ILN_151 GBV_ILN_152 GBV_ILN_161 GBV_ILN_170 GBV_ILN_171 GBV_ILN_187 GBV_ILN_213 GBV_ILN_224 GBV_ILN_230 GBV_ILN_250 GBV_ILN_281 GBV_ILN_285 GBV_ILN_293 GBV_ILN_370 GBV_ILN_602 GBV_ILN_636 GBV_ILN_702 GBV_ILN_2001 GBV_ILN_2003 GBV_ILN_2004 GBV_ILN_2005 GBV_ILN_2006 GBV_ILN_2007 GBV_ILN_2008 GBV_ILN_2009 GBV_ILN_2010 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2015 GBV_ILN_2020 GBV_ILN_2021 GBV_ILN_2025 GBV_ILN_2026 GBV_ILN_2027 GBV_ILN_2031 GBV_ILN_2034 GBV_ILN_2037 GBV_ILN_2038 GBV_ILN_2039 GBV_ILN_2044 GBV_ILN_2048 GBV_ILN_2049 GBV_ILN_2050 GBV_ILN_2055 GBV_ILN_2056 GBV_ILN_2057 GBV_ILN_2059 GBV_ILN_2061 GBV_ILN_2064 GBV_ILN_2065 GBV_ILN_2068 GBV_ILN_2088 GBV_ILN_2093 GBV_ILN_2106 GBV_ILN_2107 GBV_ILN_2108 GBV_ILN_2110 GBV_ILN_2111 GBV_ILN_2112 GBV_ILN_2113 GBV_ILN_2118 GBV_ILN_2122 GBV_ILN_2129 GBV_ILN_2143 GBV_ILN_2144 GBV_ILN_2147 GBV_ILN_2148 GBV_ILN_2152 GBV_ILN_2153 GBV_ILN_2188 GBV_ILN_2190 GBV_ILN_2232 GBV_ILN_2336 GBV_ILN_2446 GBV_ILN_2470 GBV_ILN_2472 GBV_ILN_2507 GBV_ILN_2522 GBV_ILN_2548 GBV_ILN_4035 GBV_ILN_4037 GBV_ILN_4046 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4242 GBV_ILN_4246 GBV_ILN_4249 GBV_ILN_4251 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4326 GBV_ILN_4328 GBV_ILN_4333 GBV_ILN_4334 GBV_ILN_4335 GBV_ILN_4336 GBV_ILN_4338 GBV_ILN_4393 GBV_ILN_4700 AR 380 2022 4 12 04
allfieldsGer	10.1007/s41061-022-00376-8 doi (DE-627)SPR046747990 (SPR)s41061-022-00376-8-e DE-627 ger DE-627 rakwb eng Li, Yanchen verfasserin aut Development and Challenge of Fluorescent Probes for Bioimaging Applications: From Visualization to Diagnosis 2022 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier © The Author(s), under exclusive licence to Springer Nature Switzerland AG 2022 Abstract Fluorescent probes have been used widely in bioimaging, including biological substance detection, cell imaging, in vivo biochemical reaction process tracking, and disease biomarker monitoring, and have gradually occupied an indispensable position. Compared with traditional biological imaging technologies, such as positron emission tomography (PET) and nuclear magnetic resonance imaging (MRI), the attractive advantages of fluorescent probes, such as real-time imaging, in-depth visualization, and less damage to biological samples, have made them increasingly popular. Among them, ultraviolet–visible (UV–vis) fluorescent probes still occupy the mainstream in the field of fluorescent probes due to the advantages of available structure, simple synthesis, strong versatility, and wide application. In recent years, fluorescent probes have become an indispensable tool for bioimaging and have greatly promoted the development of diagnostics. In this review, we focus on the structure, design strategies, advantages, representative probes and latest discoveries in application fields of UV–visible fluorescent probes developed in the past 3–5 years based on several fluorophores. We look forward to future development trends of fluorescent probes from the perspective of bioimaging and diagnostics. This comprehensive review may facilitate the development of more powerful fluorescent sensors for broad and exciting applications in the future. Fluorescent probe (dpeaa)DE-He213 Fluorophore structure (dpeaa)DE-He213 UV–vis fluorescent probe (dpeaa)DE-He213 Bioimaging application (dpeaa)DE-He213 Chen, Qinhua aut Pan, Xiaoyan aut Lu, Wen aut Zhang, Jie (orcid)0000-0003-2727-8806 aut Enthalten in Topics in current chemistry [Cham] : Springer International Publishing, 2016 380(2022), 4 vom: 12. Apr. (DE-627)848753445 (DE-600)2848485-X 2364-8961 nnns volume:380 year:2022 number:4 day:12 month:04 https://dx.doi.org/10.1007/s41061-022-00376-8 lizenzpflichtig Volltext GBV_USEFLAG_A SYSFLAG_A GBV_SPRINGER SSG-OLC-PHA GBV_ILN_11 GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_32 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_70 GBV_ILN_73 GBV_ILN_74 GBV_ILN_90 GBV_ILN_95 GBV_ILN_100 GBV_ILN_101 GBV_ILN_105 GBV_ILN_110 GBV_ILN_120 GBV_ILN_138 GBV_ILN_150 GBV_ILN_151 GBV_ILN_152 GBV_ILN_161 GBV_ILN_170 GBV_ILN_171 GBV_ILN_187 GBV_ILN_213 GBV_ILN_224 GBV_ILN_230 GBV_ILN_250 GBV_ILN_281 GBV_ILN_285 GBV_ILN_293 GBV_ILN_370 GBV_ILN_602 GBV_ILN_636 GBV_ILN_702 GBV_ILN_2001 GBV_ILN_2003 GBV_ILN_2004 GBV_ILN_2005 GBV_ILN_2006 GBV_ILN_2007 GBV_ILN_2008 GBV_ILN_2009 GBV_ILN_2010 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2015 GBV_ILN_2020 GBV_ILN_2021 GBV_ILN_2025 GBV_ILN_2026 GBV_ILN_2027 GBV_ILN_2031 GBV_ILN_2034 GBV_ILN_2037 GBV_ILN_2038 GBV_ILN_2039 GBV_ILN_2044 GBV_ILN_2048 GBV_ILN_2049 GBV_ILN_2050 GBV_ILN_2055 GBV_ILN_2056 GBV_ILN_2057 GBV_ILN_2059 GBV_ILN_2061 GBV_ILN_2064 GBV_ILN_2065 GBV_ILN_2068 GBV_ILN_2088 GBV_ILN_2093 GBV_ILN_2106 GBV_ILN_2107 GBV_ILN_2108 GBV_ILN_2110 GBV_ILN_2111 GBV_ILN_2112 GBV_ILN_2113 GBV_ILN_2118 GBV_ILN_2122 GBV_ILN_2129 GBV_ILN_2143 GBV_ILN_2144 GBV_ILN_2147 GBV_ILN_2148 GBV_ILN_2152 GBV_ILN_2153 GBV_ILN_2188 GBV_ILN_2190 GBV_ILN_2232 GBV_ILN_2336 GBV_ILN_2446 GBV_ILN_2470 GBV_ILN_2472 GBV_ILN_2507 GBV_ILN_2522 GBV_ILN_2548 GBV_ILN_4035 GBV_ILN_4037 GBV_ILN_4046 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4242 GBV_ILN_4246 GBV_ILN_4249 GBV_ILN_4251 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4326 GBV_ILN_4328 GBV_ILN_4333 GBV_ILN_4334 GBV_ILN_4335 GBV_ILN_4336 GBV_ILN_4338 GBV_ILN_4393 GBV_ILN_4700 AR 380 2022 4 12 04
allfieldsSound	10.1007/s41061-022-00376-8 doi (DE-627)SPR046747990 (SPR)s41061-022-00376-8-e DE-627 ger DE-627 rakwb eng Li, Yanchen verfasserin aut Development and Challenge of Fluorescent Probes for Bioimaging Applications: From Visualization to Diagnosis 2022 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier © The Author(s), under exclusive licence to Springer Nature Switzerland AG 2022 Abstract Fluorescent probes have been used widely in bioimaging, including biological substance detection, cell imaging, in vivo biochemical reaction process tracking, and disease biomarker monitoring, and have gradually occupied an indispensable position. Compared with traditional biological imaging technologies, such as positron emission tomography (PET) and nuclear magnetic resonance imaging (MRI), the attractive advantages of fluorescent probes, such as real-time imaging, in-depth visualization, and less damage to biological samples, have made them increasingly popular. Among them, ultraviolet–visible (UV–vis) fluorescent probes still occupy the mainstream in the field of fluorescent probes due to the advantages of available structure, simple synthesis, strong versatility, and wide application. In recent years, fluorescent probes have become an indispensable tool for bioimaging and have greatly promoted the development of diagnostics. In this review, we focus on the structure, design strategies, advantages, representative probes and latest discoveries in application fields of UV–visible fluorescent probes developed in the past 3–5 years based on several fluorophores. We look forward to future development trends of fluorescent probes from the perspective of bioimaging and diagnostics. This comprehensive review may facilitate the development of more powerful fluorescent sensors for broad and exciting applications in the future. Fluorescent probe (dpeaa)DE-He213 Fluorophore structure (dpeaa)DE-He213 UV–vis fluorescent probe (dpeaa)DE-He213 Bioimaging application (dpeaa)DE-He213 Chen, Qinhua aut Pan, Xiaoyan aut Lu, Wen aut Zhang, Jie (orcid)0000-0003-2727-8806 aut Enthalten in Topics in current chemistry [Cham] : Springer International Publishing, 2016 380(2022), 4 vom: 12. Apr. (DE-627)848753445 (DE-600)2848485-X 2364-8961 nnns volume:380 year:2022 number:4 day:12 month:04 https://dx.doi.org/10.1007/s41061-022-00376-8 lizenzpflichtig Volltext GBV_USEFLAG_A SYSFLAG_A GBV_SPRINGER SSG-OLC-PHA GBV_ILN_11 GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_32 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_70 GBV_ILN_73 GBV_ILN_74 GBV_ILN_90 GBV_ILN_95 GBV_ILN_100 GBV_ILN_101 GBV_ILN_105 GBV_ILN_110 GBV_ILN_120 GBV_ILN_138 GBV_ILN_150 GBV_ILN_151 GBV_ILN_152 GBV_ILN_161 GBV_ILN_170 GBV_ILN_171 GBV_ILN_187 GBV_ILN_213 GBV_ILN_224 GBV_ILN_230 GBV_ILN_250 GBV_ILN_281 GBV_ILN_285 GBV_ILN_293 GBV_ILN_370 GBV_ILN_602 GBV_ILN_636 GBV_ILN_702 GBV_ILN_2001 GBV_ILN_2003 GBV_ILN_2004 GBV_ILN_2005 GBV_ILN_2006 GBV_ILN_2007 GBV_ILN_2008 GBV_ILN_2009 GBV_ILN_2010 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2015 GBV_ILN_2020 GBV_ILN_2021 GBV_ILN_2025 GBV_ILN_2026 GBV_ILN_2027 GBV_ILN_2031 GBV_ILN_2034 GBV_ILN_2037 GBV_ILN_2038 GBV_ILN_2039 GBV_ILN_2044 GBV_ILN_2048 GBV_ILN_2049 GBV_ILN_2050 GBV_ILN_2055 GBV_ILN_2056 GBV_ILN_2057 GBV_ILN_2059 GBV_ILN_2061 GBV_ILN_2064 GBV_ILN_2065 GBV_ILN_2068 GBV_ILN_2088 GBV_ILN_2093 GBV_ILN_2106 GBV_ILN_2107 GBV_ILN_2108 GBV_ILN_2110 GBV_ILN_2111 GBV_ILN_2112 GBV_ILN_2113 GBV_ILN_2118 GBV_ILN_2122 GBV_ILN_2129 GBV_ILN_2143 GBV_ILN_2144 GBV_ILN_2147 GBV_ILN_2148 GBV_ILN_2152 GBV_ILN_2153 GBV_ILN_2188 GBV_ILN_2190 GBV_ILN_2232 GBV_ILN_2336 GBV_ILN_2446 GBV_ILN_2470 GBV_ILN_2472 GBV_ILN_2507 GBV_ILN_2522 GBV_ILN_2548 GBV_ILN_4035 GBV_ILN_4037 GBV_ILN_4046 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4242 GBV_ILN_4246 GBV_ILN_4249 GBV_ILN_4251 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4326 GBV_ILN_4328 GBV_ILN_4333 GBV_ILN_4334 GBV_ILN_4335 GBV_ILN_4336 GBV_ILN_4338 GBV_ILN_4393 GBV_ILN_4700 AR 380 2022 4 12 04
language	English
source	Enthalten in Topics in current chemistry 380(2022), 4 vom: 12. Apr. volume:380 year:2022 number:4 day:12 month:04
sourceStr	Enthalten in Topics in current chemistry 380(2022), 4 vom: 12. Apr. volume:380 year:2022 number:4 day:12 month:04
format_phy_str_mv	Article
institution	findex.gbv.de
topic_facet	Fluorescent probe Fluorophore structure UV–vis fluorescent probe Bioimaging application
isfreeaccess_bool	false
container_title	Topics in current chemistry
authorswithroles_txt_mv	Li, Yanchen @@aut@@ Chen, Qinhua @@aut@@ Pan, Xiaoyan @@aut@@ Lu, Wen @@aut@@ Zhang, Jie @@aut@@
publishDateDaySort_date	2022-04-12T00:00:00Z
hierarchy_top_id	848753445
id	SPR046747990
language_de	englisch
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author	Li, Yanchen
spellingShingle	Li, Yanchen misc Fluorescent probe misc Fluorophore structure misc UV–vis fluorescent probe misc Bioimaging application Development and Challenge of Fluorescent Probes for Bioimaging Applications: From Visualization to Diagnosis
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topic_title	Development and Challenge of Fluorescent Probes for Bioimaging Applications: From Visualization to Diagnosis Fluorescent probe (dpeaa)DE-He213 Fluorophore structure (dpeaa)DE-He213 UV–vis fluorescent probe (dpeaa)DE-He213 Bioimaging application (dpeaa)DE-He213
topic	misc Fluorescent probe misc Fluorophore structure misc UV–vis fluorescent probe misc Bioimaging application
topic_unstemmed	misc Fluorescent probe misc Fluorophore structure misc UV–vis fluorescent probe misc Bioimaging application
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title	Development and Challenge of Fluorescent Probes for Bioimaging Applications: From Visualization to Diagnosis
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title_full	Development and Challenge of Fluorescent Probes for Bioimaging Applications: From Visualization to Diagnosis
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author_browse	Li, Yanchen Chen, Qinhua Pan, Xiaoyan Lu, Wen Zhang, Jie
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title_sort	development and challenge of fluorescent probes for bioimaging applications: from visualization to diagnosis
title_auth	Development and Challenge of Fluorescent Probes for Bioimaging Applications: From Visualization to Diagnosis
abstract	Abstract Fluorescent probes have been used widely in bioimaging, including biological substance detection, cell imaging, in vivo biochemical reaction process tracking, and disease biomarker monitoring, and have gradually occupied an indispensable position. Compared with traditional biological imaging technologies, such as positron emission tomography (PET) and nuclear magnetic resonance imaging (MRI), the attractive advantages of fluorescent probes, such as real-time imaging, in-depth visualization, and less damage to biological samples, have made them increasingly popular. Among them, ultraviolet–visible (UV–vis) fluorescent probes still occupy the mainstream in the field of fluorescent probes due to the advantages of available structure, simple synthesis, strong versatility, and wide application. In recent years, fluorescent probes have become an indispensable tool for bioimaging and have greatly promoted the development of diagnostics. In this review, we focus on the structure, design strategies, advantages, representative probes and latest discoveries in application fields of UV–visible fluorescent probes developed in the past 3–5 years based on several fluorophores. We look forward to future development trends of fluorescent probes from the perspective of bioimaging and diagnostics. This comprehensive review may facilitate the development of more powerful fluorescent sensors for broad and exciting applications in the future. © The Author(s), under exclusive licence to Springer Nature Switzerland AG 2022
abstractGer	Abstract Fluorescent probes have been used widely in bioimaging, including biological substance detection, cell imaging, in vivo biochemical reaction process tracking, and disease biomarker monitoring, and have gradually occupied an indispensable position. Compared with traditional biological imaging technologies, such as positron emission tomography (PET) and nuclear magnetic resonance imaging (MRI), the attractive advantages of fluorescent probes, such as real-time imaging, in-depth visualization, and less damage to biological samples, have made them increasingly popular. Among them, ultraviolet–visible (UV–vis) fluorescent probes still occupy the mainstream in the field of fluorescent probes due to the advantages of available structure, simple synthesis, strong versatility, and wide application. In recent years, fluorescent probes have become an indispensable tool for bioimaging and have greatly promoted the development of diagnostics. In this review, we focus on the structure, design strategies, advantages, representative probes and latest discoveries in application fields of UV–visible fluorescent probes developed in the past 3–5 years based on several fluorophores. We look forward to future development trends of fluorescent probes from the perspective of bioimaging and diagnostics. This comprehensive review may facilitate the development of more powerful fluorescent sensors for broad and exciting applications in the future. © The Author(s), under exclusive licence to Springer Nature Switzerland AG 2022
abstract_unstemmed	Abstract Fluorescent probes have been used widely in bioimaging, including biological substance detection, cell imaging, in vivo biochemical reaction process tracking, and disease biomarker monitoring, and have gradually occupied an indispensable position. Compared with traditional biological imaging technologies, such as positron emission tomography (PET) and nuclear magnetic resonance imaging (MRI), the attractive advantages of fluorescent probes, such as real-time imaging, in-depth visualization, and less damage to biological samples, have made them increasingly popular. Among them, ultraviolet–visible (UV–vis) fluorescent probes still occupy the mainstream in the field of fluorescent probes due to the advantages of available structure, simple synthesis, strong versatility, and wide application. In recent years, fluorescent probes have become an indispensable tool for bioimaging and have greatly promoted the development of diagnostics. In this review, we focus on the structure, design strategies, advantages, representative probes and latest discoveries in application fields of UV–visible fluorescent probes developed in the past 3–5 years based on several fluorophores. We look forward to future development trends of fluorescent probes from the perspective of bioimaging and diagnostics. This comprehensive review may facilitate the development of more powerful fluorescent sensors for broad and exciting applications in the future. © The Author(s), under exclusive licence to Springer Nature Switzerland AG 2022
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container_issue	4
title_short	Development and Challenge of Fluorescent Probes for Bioimaging Applications: From Visualization to Diagnosis
url	https://dx.doi.org/10.1007/s41061-022-00376-8
remote_bool	true
author2	Chen, Qinhua Pan, Xiaoyan Lu, Wen Zhang, Jie
author2Str	Chen, Qinhua Pan, Xiaoyan Lu, Wen Zhang, Jie
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hochschulschrift_bool	false
doi_str	10.1007/s41061-022-00376-8
up_date	2024-07-04T00:12:24.777Z
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