Kidney length normative values in children aged 0–19 years — a multicenter study
Background Currently used pediatric kidney length normative values are based on small single-center studies, do not include kidney function assessment, and focus mostly on newborns and infants. We aimed to develop ultrasound-based kidney length normative values derived from a large group of European...
Ausführliche Beschreibung
Gespeichert in:
| Autor*in: |
Obrycki, Łukasz [verfasserIn] |
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| Format: |
E-Artikel |
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| Sprache: |
Englisch |
| Erschienen: |
2021 |
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| Schlagwörter: |
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| Anmerkung: |
© The Author(s) 2021 |
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| Übergeordnetes Werk: |
Enthalten in: Pediatric nephrology - Berlin : Springer, 1987, 37(2021), 5 vom: 16. Okt., Seite 1075-1085 |
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| Übergeordnetes Werk: |
volume:37 ; year:2021 ; number:5 ; day:16 ; month:10 ; pages:1075-1085 |
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| DOI / URN: |
10.1007/s00467-021-05303-5 |
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| Katalog-ID: |
SPR046806962 |
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| 100 | 1 | |a Obrycki, Łukasz |e verfasserin |4 aut | |
| 245 | 1 | 0 | |a Kidney length normative values in children aged 0–19 years — a multicenter study |
| 264 | 1 | |c 2021 | |
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| 520 | |a Background Currently used pediatric kidney length normative values are based on small single-center studies, do not include kidney function assessment, and focus mostly on newborns and infants. We aimed to develop ultrasound-based kidney length normative values derived from a large group of European Caucasian children with normal kidney function. Methods Out of 1,782 children aged 0–19 years, 1,758 individuals with no present or past kidney disease and normal estimated glomerular filtration rate had sonographic assessment of kidney length. The results were correlated with anthropometric parameters and estimated glomerular filtration rate. Kidney length was correlated with age, height, body surface area, and body mass index. Height-related kidney length curves and table were generated using the LMS method. Multivariate regression analysis with collinearity checks was used to evaluate kidney length predictors. Results There was no significant difference in kidney size in relation to height between boys and girls. We found significant (p < 0.001), but clinically unimportant (Cohen’s D effect size = 0.04 and 0.06) differences between prone vs. supine position (mean paired difference = 0.64 mm, 95% CI = 0.49–0.77) and left vs. right kidneys (mean paired difference = 1.03 mm, 95% CI = 0.83–1.21), respectively. For kidney length prediction, the highest coefficient correlation was observed with height (adjusted R2 = 0.87, p < 0.0001). Conclusions We present height-related LMS-percentile curves and tables of kidney length which may serve as normative values for kidney length in children from birth to 19 years of age. The most significant predictor of kidney length was statural height. Graphic Abstract | ||
| 650 | 4 | |a Kidney |7 (dpeaa)DE-He213 | |
| 650 | 4 | |a Kidney length |7 (dpeaa)DE-He213 | |
| 650 | 4 | |a Children |7 (dpeaa)DE-He213 | |
| 650 | 4 | |a Normal references |7 (dpeaa)DE-He213 | |
| 650 | 4 | |a Ultrasonography |7 (dpeaa)DE-He213 | |
| 700 | 1 | |a Sarnecki, Jędrzej |4 aut | |
| 700 | 1 | |a Lichosik, Marianna |4 aut | |
| 700 | 1 | |a Sopińska, Małgorzata |4 aut | |
| 700 | 1 | |a Placzyńska, Małgorzata |4 aut | |
| 700 | 1 | |a Stańczyk, Małgorzata |4 aut | |
| 700 | 1 | |a Mirecka, Julia |4 aut | |
| 700 | 1 | |a Wasilewska, Agnieszka |4 aut | |
| 700 | 1 | |a Michalski, Maciej |4 aut | |
| 700 | 1 | |a Lewandowska, Weronika |4 aut | |
| 700 | 1 | |a Dereziński, Tadeusz |4 aut | |
| 700 | 1 | |a Pac, Michał |4 aut | |
| 700 | 1 | |a Szwarc, Natalia |4 aut | |
| 700 | 1 | |a Annusewicz, Karol |4 aut | |
| 700 | 1 | |a Rekuta, Viktoriia |4 aut | |
| 700 | 1 | |a Ažukaitis, Karolis |4 aut | |
| 700 | 1 | |a Čekuolis, Andrius |4 aut | |
| 700 | 1 | |a Wierzbicka-Rucińska, Aldona |4 aut | |
| 700 | 1 | |a Jankauskiene, Augustina |4 aut | |
| 700 | 1 | |a Kalicki, Bolesław |4 aut | |
| 700 | 1 | |a Jobs, Katarzyna |4 aut | |
| 700 | 1 | |a Tkaczyk, Marcin |4 aut | |
| 700 | 1 | |a Feber, Janusz |4 aut | |
| 700 | 1 | |a Litwin, Mieczysław |4 aut | |
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10.1007/s00467-021-05303-5 doi (DE-627)SPR046806962 (SPR)s00467-021-05303-5-e DE-627 ger DE-627 rakwb eng Obrycki, Łukasz verfasserin aut Kidney length normative values in children aged 0–19 years — a multicenter study 2021 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier © The Author(s) 2021 Background Currently used pediatric kidney length normative values are based on small single-center studies, do not include kidney function assessment, and focus mostly on newborns and infants. We aimed to develop ultrasound-based kidney length normative values derived from a large group of European Caucasian children with normal kidney function. Methods Out of 1,782 children aged 0–19 years, 1,758 individuals with no present or past kidney disease and normal estimated glomerular filtration rate had sonographic assessment of kidney length. The results were correlated with anthropometric parameters and estimated glomerular filtration rate. Kidney length was correlated with age, height, body surface area, and body mass index. Height-related kidney length curves and table were generated using the LMS method. Multivariate regression analysis with collinearity checks was used to evaluate kidney length predictors. Results There was no significant difference in kidney size in relation to height between boys and girls. We found significant (p < 0.001), but clinically unimportant (Cohen’s D effect size = 0.04 and 0.06) differences between prone vs. supine position (mean paired difference = 0.64 mm, 95% CI = 0.49–0.77) and left vs. right kidneys (mean paired difference = 1.03 mm, 95% CI = 0.83–1.21), respectively. For kidney length prediction, the highest coefficient correlation was observed with height (adjusted R2 = 0.87, p < 0.0001). Conclusions We present height-related LMS-percentile curves and tables of kidney length which may serve as normative values for kidney length in children from birth to 19 years of age. The most significant predictor of kidney length was statural height. Graphic Abstract Kidney (dpeaa)DE-He213 Kidney length (dpeaa)DE-He213 Children (dpeaa)DE-He213 Normal references (dpeaa)DE-He213 Ultrasonography (dpeaa)DE-He213 Sarnecki, Jędrzej aut Lichosik, Marianna aut Sopińska, Małgorzata aut Placzyńska, Małgorzata aut Stańczyk, Małgorzata aut Mirecka, Julia aut Wasilewska, Agnieszka aut Michalski, Maciej aut Lewandowska, Weronika aut Dereziński, Tadeusz aut Pac, Michał aut Szwarc, Natalia aut Annusewicz, Karol aut Rekuta, Viktoriia aut Ažukaitis, Karolis aut Čekuolis, Andrius aut Wierzbicka-Rucińska, Aldona aut Jankauskiene, Augustina aut Kalicki, Bolesław aut Jobs, Katarzyna aut Tkaczyk, Marcin aut Feber, Janusz aut Litwin, Mieczysław aut Enthalten in Pediatric nephrology Berlin : Springer, 1987 37(2021), 5 vom: 16. Okt., Seite 1075-1085 (DE-627)254638872 (DE-600)1463004-7 1432-198X nnns volume:37 year:2021 number:5 day:16 month:10 pages:1075-1085 https://dx.doi.org/10.1007/s00467-021-05303-5 kostenfrei Volltext GBV_USEFLAG_A SYSFLAG_A GBV_SPRINGER SSG-OLC-PHA GBV_ILN_11 GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_32 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_69 GBV_ILN_70 GBV_ILN_73 GBV_ILN_74 GBV_ILN_90 GBV_ILN_95 GBV_ILN_100 GBV_ILN_101 GBV_ILN_105 GBV_ILN_110 GBV_ILN_120 GBV_ILN_138 GBV_ILN_150 GBV_ILN_151 GBV_ILN_152 GBV_ILN_161 GBV_ILN_170 GBV_ILN_171 GBV_ILN_187 GBV_ILN_206 GBV_ILN_213 GBV_ILN_224 GBV_ILN_230 GBV_ILN_250 GBV_ILN_267 GBV_ILN_281 GBV_ILN_285 GBV_ILN_293 GBV_ILN_370 GBV_ILN_602 GBV_ILN_636 GBV_ILN_702 GBV_ILN_711 GBV_ILN_2001 GBV_ILN_2003 GBV_ILN_2004 GBV_ILN_2005 GBV_ILN_2006 GBV_ILN_2007 GBV_ILN_2008 GBV_ILN_2009 GBV_ILN_2010 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2015 GBV_ILN_2020 GBV_ILN_2021 GBV_ILN_2025 GBV_ILN_2026 GBV_ILN_2027 GBV_ILN_2031 GBV_ILN_2034 GBV_ILN_2037 GBV_ILN_2038 GBV_ILN_2039 GBV_ILN_2044 GBV_ILN_2048 GBV_ILN_2049 GBV_ILN_2050 GBV_ILN_2055 GBV_ILN_2056 GBV_ILN_2057 GBV_ILN_2059 GBV_ILN_2061 GBV_ILN_2064 GBV_ILN_2065 GBV_ILN_2068 GBV_ILN_2088 GBV_ILN_2093 GBV_ILN_2106 GBV_ILN_2107 GBV_ILN_2108 GBV_ILN_2110 GBV_ILN_2111 GBV_ILN_2112 GBV_ILN_2113 GBV_ILN_2118 GBV_ILN_2122 GBV_ILN_2129 GBV_ILN_2143 GBV_ILN_2144 GBV_ILN_2147 GBV_ILN_2148 GBV_ILN_2152 GBV_ILN_2153 GBV_ILN_2188 GBV_ILN_2190 GBV_ILN_2232 GBV_ILN_2336 GBV_ILN_2446 GBV_ILN_2470 GBV_ILN_2472 GBV_ILN_2507 GBV_ILN_2522 GBV_ILN_2548 GBV_ILN_4035 GBV_ILN_4037 GBV_ILN_4046 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4242 GBV_ILN_4246 GBV_ILN_4249 GBV_ILN_4251 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4326 GBV_ILN_4328 GBV_ILN_4333 GBV_ILN_4334 GBV_ILN_4335 GBV_ILN_4336 GBV_ILN_4338 GBV_ILN_4393 GBV_ILN_4700 AR 37 2021 5 16 10 1075-1085 |
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10.1007/s00467-021-05303-5 doi (DE-627)SPR046806962 (SPR)s00467-021-05303-5-e DE-627 ger DE-627 rakwb eng Obrycki, Łukasz verfasserin aut Kidney length normative values in children aged 0–19 years — a multicenter study 2021 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier © The Author(s) 2021 Background Currently used pediatric kidney length normative values are based on small single-center studies, do not include kidney function assessment, and focus mostly on newborns and infants. We aimed to develop ultrasound-based kidney length normative values derived from a large group of European Caucasian children with normal kidney function. Methods Out of 1,782 children aged 0–19 years, 1,758 individuals with no present or past kidney disease and normal estimated glomerular filtration rate had sonographic assessment of kidney length. The results were correlated with anthropometric parameters and estimated glomerular filtration rate. Kidney length was correlated with age, height, body surface area, and body mass index. Height-related kidney length curves and table were generated using the LMS method. Multivariate regression analysis with collinearity checks was used to evaluate kidney length predictors. Results There was no significant difference in kidney size in relation to height between boys and girls. We found significant (p < 0.001), but clinically unimportant (Cohen’s D effect size = 0.04 and 0.06) differences between prone vs. supine position (mean paired difference = 0.64 mm, 95% CI = 0.49–0.77) and left vs. right kidneys (mean paired difference = 1.03 mm, 95% CI = 0.83–1.21), respectively. For kidney length prediction, the highest coefficient correlation was observed with height (adjusted R2 = 0.87, p < 0.0001). Conclusions We present height-related LMS-percentile curves and tables of kidney length which may serve as normative values for kidney length in children from birth to 19 years of age. The most significant predictor of kidney length was statural height. Graphic Abstract Kidney (dpeaa)DE-He213 Kidney length (dpeaa)DE-He213 Children (dpeaa)DE-He213 Normal references (dpeaa)DE-He213 Ultrasonography (dpeaa)DE-He213 Sarnecki, Jędrzej aut Lichosik, Marianna aut Sopińska, Małgorzata aut Placzyńska, Małgorzata aut Stańczyk, Małgorzata aut Mirecka, Julia aut Wasilewska, Agnieszka aut Michalski, Maciej aut Lewandowska, Weronika aut Dereziński, Tadeusz aut Pac, Michał aut Szwarc, Natalia aut Annusewicz, Karol aut Rekuta, Viktoriia aut Ažukaitis, Karolis aut Čekuolis, Andrius aut Wierzbicka-Rucińska, Aldona aut Jankauskiene, Augustina aut Kalicki, Bolesław aut Jobs, Katarzyna aut Tkaczyk, Marcin aut Feber, Janusz aut Litwin, Mieczysław aut Enthalten in Pediatric nephrology Berlin : Springer, 1987 37(2021), 5 vom: 16. Okt., Seite 1075-1085 (DE-627)254638872 (DE-600)1463004-7 1432-198X nnns volume:37 year:2021 number:5 day:16 month:10 pages:1075-1085 https://dx.doi.org/10.1007/s00467-021-05303-5 kostenfrei Volltext GBV_USEFLAG_A SYSFLAG_A GBV_SPRINGER SSG-OLC-PHA GBV_ILN_11 GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_32 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_69 GBV_ILN_70 GBV_ILN_73 GBV_ILN_74 GBV_ILN_90 GBV_ILN_95 GBV_ILN_100 GBV_ILN_101 GBV_ILN_105 GBV_ILN_110 GBV_ILN_120 GBV_ILN_138 GBV_ILN_150 GBV_ILN_151 GBV_ILN_152 GBV_ILN_161 GBV_ILN_170 GBV_ILN_171 GBV_ILN_187 GBV_ILN_206 GBV_ILN_213 GBV_ILN_224 GBV_ILN_230 GBV_ILN_250 GBV_ILN_267 GBV_ILN_281 GBV_ILN_285 GBV_ILN_293 GBV_ILN_370 GBV_ILN_602 GBV_ILN_636 GBV_ILN_702 GBV_ILN_711 GBV_ILN_2001 GBV_ILN_2003 GBV_ILN_2004 GBV_ILN_2005 GBV_ILN_2006 GBV_ILN_2007 GBV_ILN_2008 GBV_ILN_2009 GBV_ILN_2010 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2015 GBV_ILN_2020 GBV_ILN_2021 GBV_ILN_2025 GBV_ILN_2026 GBV_ILN_2027 GBV_ILN_2031 GBV_ILN_2034 GBV_ILN_2037 GBV_ILN_2038 GBV_ILN_2039 GBV_ILN_2044 GBV_ILN_2048 GBV_ILN_2049 GBV_ILN_2050 GBV_ILN_2055 GBV_ILN_2056 GBV_ILN_2057 GBV_ILN_2059 GBV_ILN_2061 GBV_ILN_2064 GBV_ILN_2065 GBV_ILN_2068 GBV_ILN_2088 GBV_ILN_2093 GBV_ILN_2106 GBV_ILN_2107 GBV_ILN_2108 GBV_ILN_2110 GBV_ILN_2111 GBV_ILN_2112 GBV_ILN_2113 GBV_ILN_2118 GBV_ILN_2122 GBV_ILN_2129 GBV_ILN_2143 GBV_ILN_2144 GBV_ILN_2147 GBV_ILN_2148 GBV_ILN_2152 GBV_ILN_2153 GBV_ILN_2188 GBV_ILN_2190 GBV_ILN_2232 GBV_ILN_2336 GBV_ILN_2446 GBV_ILN_2470 GBV_ILN_2472 GBV_ILN_2507 GBV_ILN_2522 GBV_ILN_2548 GBV_ILN_4035 GBV_ILN_4037 GBV_ILN_4046 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4242 GBV_ILN_4246 GBV_ILN_4249 GBV_ILN_4251 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4326 GBV_ILN_4328 GBV_ILN_4333 GBV_ILN_4334 GBV_ILN_4335 GBV_ILN_4336 GBV_ILN_4338 GBV_ILN_4393 GBV_ILN_4700 AR 37 2021 5 16 10 1075-1085 |
| allfields_unstemmed |
10.1007/s00467-021-05303-5 doi (DE-627)SPR046806962 (SPR)s00467-021-05303-5-e DE-627 ger DE-627 rakwb eng Obrycki, Łukasz verfasserin aut Kidney length normative values in children aged 0–19 years — a multicenter study 2021 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier © The Author(s) 2021 Background Currently used pediatric kidney length normative values are based on small single-center studies, do not include kidney function assessment, and focus mostly on newborns and infants. We aimed to develop ultrasound-based kidney length normative values derived from a large group of European Caucasian children with normal kidney function. Methods Out of 1,782 children aged 0–19 years, 1,758 individuals with no present or past kidney disease and normal estimated glomerular filtration rate had sonographic assessment of kidney length. The results were correlated with anthropometric parameters and estimated glomerular filtration rate. Kidney length was correlated with age, height, body surface area, and body mass index. Height-related kidney length curves and table were generated using the LMS method. Multivariate regression analysis with collinearity checks was used to evaluate kidney length predictors. Results There was no significant difference in kidney size in relation to height between boys and girls. We found significant (p < 0.001), but clinically unimportant (Cohen’s D effect size = 0.04 and 0.06) differences between prone vs. supine position (mean paired difference = 0.64 mm, 95% CI = 0.49–0.77) and left vs. right kidneys (mean paired difference = 1.03 mm, 95% CI = 0.83–1.21), respectively. For kidney length prediction, the highest coefficient correlation was observed with height (adjusted R2 = 0.87, p < 0.0001). Conclusions We present height-related LMS-percentile curves and tables of kidney length which may serve as normative values for kidney length in children from birth to 19 years of age. The most significant predictor of kidney length was statural height. Graphic Abstract Kidney (dpeaa)DE-He213 Kidney length (dpeaa)DE-He213 Children (dpeaa)DE-He213 Normal references (dpeaa)DE-He213 Ultrasonography (dpeaa)DE-He213 Sarnecki, Jędrzej aut Lichosik, Marianna aut Sopińska, Małgorzata aut Placzyńska, Małgorzata aut Stańczyk, Małgorzata aut Mirecka, Julia aut Wasilewska, Agnieszka aut Michalski, Maciej aut Lewandowska, Weronika aut Dereziński, Tadeusz aut Pac, Michał aut Szwarc, Natalia aut Annusewicz, Karol aut Rekuta, Viktoriia aut Ažukaitis, Karolis aut Čekuolis, Andrius aut Wierzbicka-Rucińska, Aldona aut Jankauskiene, Augustina aut Kalicki, Bolesław aut Jobs, Katarzyna aut Tkaczyk, Marcin aut Feber, Janusz aut Litwin, Mieczysław aut Enthalten in Pediatric nephrology Berlin : Springer, 1987 37(2021), 5 vom: 16. Okt., Seite 1075-1085 (DE-627)254638872 (DE-600)1463004-7 1432-198X nnns volume:37 year:2021 number:5 day:16 month:10 pages:1075-1085 https://dx.doi.org/10.1007/s00467-021-05303-5 kostenfrei Volltext GBV_USEFLAG_A SYSFLAG_A GBV_SPRINGER SSG-OLC-PHA GBV_ILN_11 GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_32 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_69 GBV_ILN_70 GBV_ILN_73 GBV_ILN_74 GBV_ILN_90 GBV_ILN_95 GBV_ILN_100 GBV_ILN_101 GBV_ILN_105 GBV_ILN_110 GBV_ILN_120 GBV_ILN_138 GBV_ILN_150 GBV_ILN_151 GBV_ILN_152 GBV_ILN_161 GBV_ILN_170 GBV_ILN_171 GBV_ILN_187 GBV_ILN_206 GBV_ILN_213 GBV_ILN_224 GBV_ILN_230 GBV_ILN_250 GBV_ILN_267 GBV_ILN_281 GBV_ILN_285 GBV_ILN_293 GBV_ILN_370 GBV_ILN_602 GBV_ILN_636 GBV_ILN_702 GBV_ILN_711 GBV_ILN_2001 GBV_ILN_2003 GBV_ILN_2004 GBV_ILN_2005 GBV_ILN_2006 GBV_ILN_2007 GBV_ILN_2008 GBV_ILN_2009 GBV_ILN_2010 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2015 GBV_ILN_2020 GBV_ILN_2021 GBV_ILN_2025 GBV_ILN_2026 GBV_ILN_2027 GBV_ILN_2031 GBV_ILN_2034 GBV_ILN_2037 GBV_ILN_2038 GBV_ILN_2039 GBV_ILN_2044 GBV_ILN_2048 GBV_ILN_2049 GBV_ILN_2050 GBV_ILN_2055 GBV_ILN_2056 GBV_ILN_2057 GBV_ILN_2059 GBV_ILN_2061 GBV_ILN_2064 GBV_ILN_2065 GBV_ILN_2068 GBV_ILN_2088 GBV_ILN_2093 GBV_ILN_2106 GBV_ILN_2107 GBV_ILN_2108 GBV_ILN_2110 GBV_ILN_2111 GBV_ILN_2112 GBV_ILN_2113 GBV_ILN_2118 GBV_ILN_2122 GBV_ILN_2129 GBV_ILN_2143 GBV_ILN_2144 GBV_ILN_2147 GBV_ILN_2148 GBV_ILN_2152 GBV_ILN_2153 GBV_ILN_2188 GBV_ILN_2190 GBV_ILN_2232 GBV_ILN_2336 GBV_ILN_2446 GBV_ILN_2470 GBV_ILN_2472 GBV_ILN_2507 GBV_ILN_2522 GBV_ILN_2548 GBV_ILN_4035 GBV_ILN_4037 GBV_ILN_4046 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4242 GBV_ILN_4246 GBV_ILN_4249 GBV_ILN_4251 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4326 GBV_ILN_4328 GBV_ILN_4333 GBV_ILN_4334 GBV_ILN_4335 GBV_ILN_4336 GBV_ILN_4338 GBV_ILN_4393 GBV_ILN_4700 AR 37 2021 5 16 10 1075-1085 |
| allfieldsGer |
10.1007/s00467-021-05303-5 doi (DE-627)SPR046806962 (SPR)s00467-021-05303-5-e DE-627 ger DE-627 rakwb eng Obrycki, Łukasz verfasserin aut Kidney length normative values in children aged 0–19 years — a multicenter study 2021 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier © The Author(s) 2021 Background Currently used pediatric kidney length normative values are based on small single-center studies, do not include kidney function assessment, and focus mostly on newborns and infants. We aimed to develop ultrasound-based kidney length normative values derived from a large group of European Caucasian children with normal kidney function. Methods Out of 1,782 children aged 0–19 years, 1,758 individuals with no present or past kidney disease and normal estimated glomerular filtration rate had sonographic assessment of kidney length. The results were correlated with anthropometric parameters and estimated glomerular filtration rate. Kidney length was correlated with age, height, body surface area, and body mass index. Height-related kidney length curves and table were generated using the LMS method. Multivariate regression analysis with collinearity checks was used to evaluate kidney length predictors. Results There was no significant difference in kidney size in relation to height between boys and girls. We found significant (p < 0.001), but clinically unimportant (Cohen’s D effect size = 0.04 and 0.06) differences between prone vs. supine position (mean paired difference = 0.64 mm, 95% CI = 0.49–0.77) and left vs. right kidneys (mean paired difference = 1.03 mm, 95% CI = 0.83–1.21), respectively. For kidney length prediction, the highest coefficient correlation was observed with height (adjusted R2 = 0.87, p < 0.0001). Conclusions We present height-related LMS-percentile curves and tables of kidney length which may serve as normative values for kidney length in children from birth to 19 years of age. The most significant predictor of kidney length was statural height. Graphic Abstract Kidney (dpeaa)DE-He213 Kidney length (dpeaa)DE-He213 Children (dpeaa)DE-He213 Normal references (dpeaa)DE-He213 Ultrasonography (dpeaa)DE-He213 Sarnecki, Jędrzej aut Lichosik, Marianna aut Sopińska, Małgorzata aut Placzyńska, Małgorzata aut Stańczyk, Małgorzata aut Mirecka, Julia aut Wasilewska, Agnieszka aut Michalski, Maciej aut Lewandowska, Weronika aut Dereziński, Tadeusz aut Pac, Michał aut Szwarc, Natalia aut Annusewicz, Karol aut Rekuta, Viktoriia aut Ažukaitis, Karolis aut Čekuolis, Andrius aut Wierzbicka-Rucińska, Aldona aut Jankauskiene, Augustina aut Kalicki, Bolesław aut Jobs, Katarzyna aut Tkaczyk, Marcin aut Feber, Janusz aut Litwin, Mieczysław aut Enthalten in Pediatric nephrology Berlin : Springer, 1987 37(2021), 5 vom: 16. Okt., Seite 1075-1085 (DE-627)254638872 (DE-600)1463004-7 1432-198X nnns volume:37 year:2021 number:5 day:16 month:10 pages:1075-1085 https://dx.doi.org/10.1007/s00467-021-05303-5 kostenfrei Volltext GBV_USEFLAG_A SYSFLAG_A GBV_SPRINGER SSG-OLC-PHA GBV_ILN_11 GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_32 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_69 GBV_ILN_70 GBV_ILN_73 GBV_ILN_74 GBV_ILN_90 GBV_ILN_95 GBV_ILN_100 GBV_ILN_101 GBV_ILN_105 GBV_ILN_110 GBV_ILN_120 GBV_ILN_138 GBV_ILN_150 GBV_ILN_151 GBV_ILN_152 GBV_ILN_161 GBV_ILN_170 GBV_ILN_171 GBV_ILN_187 GBV_ILN_206 GBV_ILN_213 GBV_ILN_224 GBV_ILN_230 GBV_ILN_250 GBV_ILN_267 GBV_ILN_281 GBV_ILN_285 GBV_ILN_293 GBV_ILN_370 GBV_ILN_602 GBV_ILN_636 GBV_ILN_702 GBV_ILN_711 GBV_ILN_2001 GBV_ILN_2003 GBV_ILN_2004 GBV_ILN_2005 GBV_ILN_2006 GBV_ILN_2007 GBV_ILN_2008 GBV_ILN_2009 GBV_ILN_2010 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2015 GBV_ILN_2020 GBV_ILN_2021 GBV_ILN_2025 GBV_ILN_2026 GBV_ILN_2027 GBV_ILN_2031 GBV_ILN_2034 GBV_ILN_2037 GBV_ILN_2038 GBV_ILN_2039 GBV_ILN_2044 GBV_ILN_2048 GBV_ILN_2049 GBV_ILN_2050 GBV_ILN_2055 GBV_ILN_2056 GBV_ILN_2057 GBV_ILN_2059 GBV_ILN_2061 GBV_ILN_2064 GBV_ILN_2065 GBV_ILN_2068 GBV_ILN_2088 GBV_ILN_2093 GBV_ILN_2106 GBV_ILN_2107 GBV_ILN_2108 GBV_ILN_2110 GBV_ILN_2111 GBV_ILN_2112 GBV_ILN_2113 GBV_ILN_2118 GBV_ILN_2122 GBV_ILN_2129 GBV_ILN_2143 GBV_ILN_2144 GBV_ILN_2147 GBV_ILN_2148 GBV_ILN_2152 GBV_ILN_2153 GBV_ILN_2188 GBV_ILN_2190 GBV_ILN_2232 GBV_ILN_2336 GBV_ILN_2446 GBV_ILN_2470 GBV_ILN_2472 GBV_ILN_2507 GBV_ILN_2522 GBV_ILN_2548 GBV_ILN_4035 GBV_ILN_4037 GBV_ILN_4046 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4242 GBV_ILN_4246 GBV_ILN_4249 GBV_ILN_4251 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4326 GBV_ILN_4328 GBV_ILN_4333 GBV_ILN_4334 GBV_ILN_4335 GBV_ILN_4336 GBV_ILN_4338 GBV_ILN_4393 GBV_ILN_4700 AR 37 2021 5 16 10 1075-1085 |
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10.1007/s00467-021-05303-5 doi (DE-627)SPR046806962 (SPR)s00467-021-05303-5-e DE-627 ger DE-627 rakwb eng Obrycki, Łukasz verfasserin aut Kidney length normative values in children aged 0–19 years — a multicenter study 2021 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier © The Author(s) 2021 Background Currently used pediatric kidney length normative values are based on small single-center studies, do not include kidney function assessment, and focus mostly on newborns and infants. We aimed to develop ultrasound-based kidney length normative values derived from a large group of European Caucasian children with normal kidney function. Methods Out of 1,782 children aged 0–19 years, 1,758 individuals with no present or past kidney disease and normal estimated glomerular filtration rate had sonographic assessment of kidney length. The results were correlated with anthropometric parameters and estimated glomerular filtration rate. Kidney length was correlated with age, height, body surface area, and body mass index. Height-related kidney length curves and table were generated using the LMS method. Multivariate regression analysis with collinearity checks was used to evaluate kidney length predictors. Results There was no significant difference in kidney size in relation to height between boys and girls. We found significant (p < 0.001), but clinically unimportant (Cohen’s D effect size = 0.04 and 0.06) differences between prone vs. supine position (mean paired difference = 0.64 mm, 95% CI = 0.49–0.77) and left vs. right kidneys (mean paired difference = 1.03 mm, 95% CI = 0.83–1.21), respectively. For kidney length prediction, the highest coefficient correlation was observed with height (adjusted R2 = 0.87, p < 0.0001). Conclusions We present height-related LMS-percentile curves and tables of kidney length which may serve as normative values for kidney length in children from birth to 19 years of age. The most significant predictor of kidney length was statural height. Graphic Abstract Kidney (dpeaa)DE-He213 Kidney length (dpeaa)DE-He213 Children (dpeaa)DE-He213 Normal references (dpeaa)DE-He213 Ultrasonography (dpeaa)DE-He213 Sarnecki, Jędrzej aut Lichosik, Marianna aut Sopińska, Małgorzata aut Placzyńska, Małgorzata aut Stańczyk, Małgorzata aut Mirecka, Julia aut Wasilewska, Agnieszka aut Michalski, Maciej aut Lewandowska, Weronika aut Dereziński, Tadeusz aut Pac, Michał aut Szwarc, Natalia aut Annusewicz, Karol aut Rekuta, Viktoriia aut Ažukaitis, Karolis aut Čekuolis, Andrius aut Wierzbicka-Rucińska, Aldona aut Jankauskiene, Augustina aut Kalicki, Bolesław aut Jobs, Katarzyna aut Tkaczyk, Marcin aut Feber, Janusz aut Litwin, Mieczysław aut Enthalten in Pediatric nephrology Berlin : Springer, 1987 37(2021), 5 vom: 16. Okt., Seite 1075-1085 (DE-627)254638872 (DE-600)1463004-7 1432-198X nnns volume:37 year:2021 number:5 day:16 month:10 pages:1075-1085 https://dx.doi.org/10.1007/s00467-021-05303-5 kostenfrei Volltext GBV_USEFLAG_A SYSFLAG_A GBV_SPRINGER SSG-OLC-PHA GBV_ILN_11 GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_32 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_69 GBV_ILN_70 GBV_ILN_73 GBV_ILN_74 GBV_ILN_90 GBV_ILN_95 GBV_ILN_100 GBV_ILN_101 GBV_ILN_105 GBV_ILN_110 GBV_ILN_120 GBV_ILN_138 GBV_ILN_150 GBV_ILN_151 GBV_ILN_152 GBV_ILN_161 GBV_ILN_170 GBV_ILN_171 GBV_ILN_187 GBV_ILN_206 GBV_ILN_213 GBV_ILN_224 GBV_ILN_230 GBV_ILN_250 GBV_ILN_267 GBV_ILN_281 GBV_ILN_285 GBV_ILN_293 GBV_ILN_370 GBV_ILN_602 GBV_ILN_636 GBV_ILN_702 GBV_ILN_711 GBV_ILN_2001 GBV_ILN_2003 GBV_ILN_2004 GBV_ILN_2005 GBV_ILN_2006 GBV_ILN_2007 GBV_ILN_2008 GBV_ILN_2009 GBV_ILN_2010 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2015 GBV_ILN_2020 GBV_ILN_2021 GBV_ILN_2025 GBV_ILN_2026 GBV_ILN_2027 GBV_ILN_2031 GBV_ILN_2034 GBV_ILN_2037 GBV_ILN_2038 GBV_ILN_2039 GBV_ILN_2044 GBV_ILN_2048 GBV_ILN_2049 GBV_ILN_2050 GBV_ILN_2055 GBV_ILN_2056 GBV_ILN_2057 GBV_ILN_2059 GBV_ILN_2061 GBV_ILN_2064 GBV_ILN_2065 GBV_ILN_2068 GBV_ILN_2088 GBV_ILN_2093 GBV_ILN_2106 GBV_ILN_2107 GBV_ILN_2108 GBV_ILN_2110 GBV_ILN_2111 GBV_ILN_2112 GBV_ILN_2113 GBV_ILN_2118 GBV_ILN_2122 GBV_ILN_2129 GBV_ILN_2143 GBV_ILN_2144 GBV_ILN_2147 GBV_ILN_2148 GBV_ILN_2152 GBV_ILN_2153 GBV_ILN_2188 GBV_ILN_2190 GBV_ILN_2232 GBV_ILN_2336 GBV_ILN_2446 GBV_ILN_2470 GBV_ILN_2472 GBV_ILN_2507 GBV_ILN_2522 GBV_ILN_2548 GBV_ILN_4035 GBV_ILN_4037 GBV_ILN_4046 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4242 GBV_ILN_4246 GBV_ILN_4249 GBV_ILN_4251 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4326 GBV_ILN_4328 GBV_ILN_4333 GBV_ILN_4334 GBV_ILN_4335 GBV_ILN_4336 GBV_ILN_4338 GBV_ILN_4393 GBV_ILN_4700 AR 37 2021 5 16 10 1075-1085 |
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Obrycki, Łukasz @@aut@@ Sarnecki, Jędrzej @@aut@@ Lichosik, Marianna @@aut@@ Sopińska, Małgorzata @@aut@@ Placzyńska, Małgorzata @@aut@@ Stańczyk, Małgorzata @@aut@@ Mirecka, Julia @@aut@@ Wasilewska, Agnieszka @@aut@@ Michalski, Maciej @@aut@@ Lewandowska, Weronika @@aut@@ Dereziński, Tadeusz @@aut@@ Pac, Michał @@aut@@ Szwarc, Natalia @@aut@@ Annusewicz, Karol @@aut@@ Rekuta, Viktoriia @@aut@@ Ažukaitis, Karolis @@aut@@ Čekuolis, Andrius @@aut@@ Wierzbicka-Rucińska, Aldona @@aut@@ Jankauskiene, Augustina @@aut@@ Kalicki, Bolesław @@aut@@ Jobs, Katarzyna @@aut@@ Tkaczyk, Marcin @@aut@@ Feber, Janusz @@aut@@ Litwin, Mieczysław @@aut@@ |
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We aimed to develop ultrasound-based kidney length normative values derived from a large group of European Caucasian children with normal kidney function. Methods Out of 1,782 children aged 0–19 years, 1,758 individuals with no present or past kidney disease and normal estimated glomerular filtration rate had sonographic assessment of kidney length. The results were correlated with anthropometric parameters and estimated glomerular filtration rate. Kidney length was correlated with age, height, body surface area, and body mass index. Height-related kidney length curves and table were generated using the LMS method. Multivariate regression analysis with collinearity checks was used to evaluate kidney length predictors. Results There was no significant difference in kidney size in relation to height between boys and girls. 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Obrycki, Łukasz |
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Obrycki, Łukasz misc Kidney misc Kidney length misc Children misc Normal references misc Ultrasonography Kidney length normative values in children aged 0–19 years — a multicenter study |
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1432-198X |
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Kidney length normative values in children aged 0–19 years — a multicenter study Kidney (dpeaa)DE-He213 Kidney length (dpeaa)DE-He213 Children (dpeaa)DE-He213 Normal references (dpeaa)DE-He213 Ultrasonography (dpeaa)DE-He213 |
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misc Kidney misc Kidney length misc Children misc Normal references misc Ultrasonography |
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misc Kidney misc Kidney length misc Children misc Normal references misc Ultrasonography |
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Pediatric nephrology |
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Pediatric nephrology |
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Kidney length normative values in children aged 0–19 years — a multicenter study |
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Kidney length normative values in children aged 0–19 years — a multicenter study |
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Obrycki, Łukasz |
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Pediatric nephrology |
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Pediatric nephrology |
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Obrycki, Łukasz Sarnecki, Jędrzej Lichosik, Marianna Sopińska, Małgorzata Placzyńska, Małgorzata Stańczyk, Małgorzata Mirecka, Julia Wasilewska, Agnieszka Michalski, Maciej Lewandowska, Weronika Dereziński, Tadeusz Pac, Michał Szwarc, Natalia Annusewicz, Karol Rekuta, Viktoriia Ažukaitis, Karolis Čekuolis, Andrius Wierzbicka-Rucińska, Aldona Jankauskiene, Augustina Kalicki, Bolesław Jobs, Katarzyna Tkaczyk, Marcin Feber, Janusz Litwin, Mieczysław |
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37 |
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Elektronische Aufsätze |
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Obrycki, Łukasz |
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10.1007/s00467-021-05303-5 |
| title_sort |
kidney length normative values in children aged 0–19 years — a multicenter study |
| title_auth |
Kidney length normative values in children aged 0–19 years — a multicenter study |
| abstract |
Background Currently used pediatric kidney length normative values are based on small single-center studies, do not include kidney function assessment, and focus mostly on newborns and infants. We aimed to develop ultrasound-based kidney length normative values derived from a large group of European Caucasian children with normal kidney function. Methods Out of 1,782 children aged 0–19 years, 1,758 individuals with no present or past kidney disease and normal estimated glomerular filtration rate had sonographic assessment of kidney length. The results were correlated with anthropometric parameters and estimated glomerular filtration rate. Kidney length was correlated with age, height, body surface area, and body mass index. Height-related kidney length curves and table were generated using the LMS method. Multivariate regression analysis with collinearity checks was used to evaluate kidney length predictors. Results There was no significant difference in kidney size in relation to height between boys and girls. We found significant (p < 0.001), but clinically unimportant (Cohen’s D effect size = 0.04 and 0.06) differences between prone vs. supine position (mean paired difference = 0.64 mm, 95% CI = 0.49–0.77) and left vs. right kidneys (mean paired difference = 1.03 mm, 95% CI = 0.83–1.21), respectively. For kidney length prediction, the highest coefficient correlation was observed with height (adjusted R2 = 0.87, p < 0.0001). Conclusions We present height-related LMS-percentile curves and tables of kidney length which may serve as normative values for kidney length in children from birth to 19 years of age. The most significant predictor of kidney length was statural height. Graphic Abstract © The Author(s) 2021 |
| abstractGer |
Background Currently used pediatric kidney length normative values are based on small single-center studies, do not include kidney function assessment, and focus mostly on newborns and infants. We aimed to develop ultrasound-based kidney length normative values derived from a large group of European Caucasian children with normal kidney function. Methods Out of 1,782 children aged 0–19 years, 1,758 individuals with no present or past kidney disease and normal estimated glomerular filtration rate had sonographic assessment of kidney length. The results were correlated with anthropometric parameters and estimated glomerular filtration rate. Kidney length was correlated with age, height, body surface area, and body mass index. Height-related kidney length curves and table were generated using the LMS method. Multivariate regression analysis with collinearity checks was used to evaluate kidney length predictors. Results There was no significant difference in kidney size in relation to height between boys and girls. We found significant (p < 0.001), but clinically unimportant (Cohen’s D effect size = 0.04 and 0.06) differences between prone vs. supine position (mean paired difference = 0.64 mm, 95% CI = 0.49–0.77) and left vs. right kidneys (mean paired difference = 1.03 mm, 95% CI = 0.83–1.21), respectively. For kidney length prediction, the highest coefficient correlation was observed with height (adjusted R2 = 0.87, p < 0.0001). Conclusions We present height-related LMS-percentile curves and tables of kidney length which may serve as normative values for kidney length in children from birth to 19 years of age. The most significant predictor of kidney length was statural height. Graphic Abstract © The Author(s) 2021 |
| abstract_unstemmed |
Background Currently used pediatric kidney length normative values are based on small single-center studies, do not include kidney function assessment, and focus mostly on newborns and infants. We aimed to develop ultrasound-based kidney length normative values derived from a large group of European Caucasian children with normal kidney function. Methods Out of 1,782 children aged 0–19 years, 1,758 individuals with no present or past kidney disease and normal estimated glomerular filtration rate had sonographic assessment of kidney length. The results were correlated with anthropometric parameters and estimated glomerular filtration rate. Kidney length was correlated with age, height, body surface area, and body mass index. Height-related kidney length curves and table were generated using the LMS method. Multivariate regression analysis with collinearity checks was used to evaluate kidney length predictors. Results There was no significant difference in kidney size in relation to height between boys and girls. We found significant (p < 0.001), but clinically unimportant (Cohen’s D effect size = 0.04 and 0.06) differences between prone vs. supine position (mean paired difference = 0.64 mm, 95% CI = 0.49–0.77) and left vs. right kidneys (mean paired difference = 1.03 mm, 95% CI = 0.83–1.21), respectively. For kidney length prediction, the highest coefficient correlation was observed with height (adjusted R2 = 0.87, p < 0.0001). Conclusions We present height-related LMS-percentile curves and tables of kidney length which may serve as normative values for kidney length in children from birth to 19 years of age. The most significant predictor of kidney length was statural height. Graphic Abstract © The Author(s) 2021 |
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| title_short |
Kidney length normative values in children aged 0–19 years — a multicenter study |
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https://dx.doi.org/10.1007/s00467-021-05303-5 |
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Sarnecki, Jędrzej Lichosik, Marianna Sopińska, Małgorzata Placzyńska, Małgorzata Stańczyk, Małgorzata Mirecka, Julia Wasilewska, Agnieszka Michalski, Maciej Lewandowska, Weronika Dereziński, Tadeusz Pac, Michał Szwarc, Natalia Annusewicz, Karol Rekuta, Viktoriia Ažukaitis, Karolis Čekuolis, Andrius Wierzbicka-Rucińska, Aldona Jankauskiene, Augustina Kalicki, Bolesław Jobs, Katarzyna Tkaczyk, Marcin Feber, Janusz Litwin, Mieczysław |
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Sarnecki, Jędrzej Lichosik, Marianna Sopińska, Małgorzata Placzyńska, Małgorzata Stańczyk, Małgorzata Mirecka, Julia Wasilewska, Agnieszka Michalski, Maciej Lewandowska, Weronika Dereziński, Tadeusz Pac, Michał Szwarc, Natalia Annusewicz, Karol Rekuta, Viktoriia Ažukaitis, Karolis Čekuolis, Andrius Wierzbicka-Rucińska, Aldona Jankauskiene, Augustina Kalicki, Bolesław Jobs, Katarzyna Tkaczyk, Marcin Feber, Janusz Litwin, Mieczysław |
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10.1007/s00467-021-05303-5 |
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2024-07-04T00:30:28.467Z |
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<?xml version="1.0" encoding="UTF-8"?><collection xmlns="http://www.loc.gov/MARC21/slim"><record><leader>01000caa a22002652 4500</leader><controlfield tag="001">SPR046806962</controlfield><controlfield tag="003">DE-627</controlfield><controlfield tag="005">20230519233604.0</controlfield><controlfield tag="007">cr uuu---uuuuu</controlfield><controlfield tag="008">220422s2021 xx |||||o 00| ||eng c</controlfield><datafield tag="024" ind1="7" ind2=" "><subfield code="a">10.1007/s00467-021-05303-5</subfield><subfield code="2">doi</subfield></datafield><datafield tag="035" ind1=" " ind2=" "><subfield code="a">(DE-627)SPR046806962</subfield></datafield><datafield tag="035" ind1=" " ind2=" "><subfield code="a">(SPR)s00467-021-05303-5-e</subfield></datafield><datafield tag="040" ind1=" " ind2=" "><subfield code="a">DE-627</subfield><subfield code="b">ger</subfield><subfield code="c">DE-627</subfield><subfield code="e">rakwb</subfield></datafield><datafield tag="041" ind1=" " ind2=" "><subfield code="a">eng</subfield></datafield><datafield tag="100" ind1="1" ind2=" "><subfield code="a">Obrycki, Łukasz</subfield><subfield code="e">verfasserin</subfield><subfield code="4">aut</subfield></datafield><datafield tag="245" ind1="1" ind2="0"><subfield code="a">Kidney length normative values in children aged 0–19 years — a multicenter study</subfield></datafield><datafield tag="264" ind1=" " ind2="1"><subfield code="c">2021</subfield></datafield><datafield tag="336" ind1=" " ind2=" "><subfield code="a">Text</subfield><subfield code="b">txt</subfield><subfield code="2">rdacontent</subfield></datafield><datafield tag="337" ind1=" " ind2=" "><subfield code="a">Computermedien</subfield><subfield code="b">c</subfield><subfield code="2">rdamedia</subfield></datafield><datafield tag="338" ind1=" " ind2=" "><subfield code="a">Online-Ressource</subfield><subfield code="b">cr</subfield><subfield code="2">rdacarrier</subfield></datafield><datafield tag="500" ind1=" " ind2=" "><subfield code="a">© The Author(s) 2021</subfield></datafield><datafield tag="520" ind1=" " ind2=" "><subfield code="a">Background Currently used pediatric kidney length normative values are based on small single-center studies, do not include kidney function assessment, and focus mostly on newborns and infants. We aimed to develop ultrasound-based kidney length normative values derived from a large group of European Caucasian children with normal kidney function. Methods Out of 1,782 children aged 0–19 years, 1,758 individuals with no present or past kidney disease and normal estimated glomerular filtration rate had sonographic assessment of kidney length. The results were correlated with anthropometric parameters and estimated glomerular filtration rate. Kidney length was correlated with age, height, body surface area, and body mass index. Height-related kidney length curves and table were generated using the LMS method. Multivariate regression analysis with collinearity checks was used to evaluate kidney length predictors. Results There was no significant difference in kidney size in relation to height between boys and girls. We found significant (p < 0.001), but clinically unimportant (Cohen’s D effect size = 0.04 and 0.06) differences between prone vs. supine position (mean paired difference = 0.64 mm, 95% CI = 0.49–0.77) and left vs. right kidneys (mean paired difference = 1.03 mm, 95% CI = 0.83–1.21), respectively. For kidney length prediction, the highest coefficient correlation was observed with height (adjusted R2 = 0.87, p < 0.0001). Conclusions We present height-related LMS-percentile curves and tables of kidney length which may serve as normative values for kidney length in children from birth to 19 years of age. The most significant predictor of kidney length was statural height. 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| score |
7.399638 |