A prospective, interventional study comparing the outcomes of macular hole surgery in eyes randomized to $ C_{3} %$ F_{8} $, $ C_{2} %$ F_{6,} $ or $ SF_{6} $ gas tamponade

Purpose Analysis of outcomes of macular hole (MH) surgery using 12% $ C_{3} %$ F_{8} $, 16% $ C_{2} %$ F_{6} $, or 18% $ SF_{6} $ as randomized gas tamponading agent. Methods This is a prospective, randomized, interventional study of 159 eyes with idiopathic MH undergoing 23/25G pars-plana vitrectomy with internal limiting membrane peeling and gas tamponade. Eyes were stratified into two groups: Group I (MH < 800 µ) and group II (MH > 800 µ) according to MH apical diameter. Eyes in group I were randomized to receive either 18% $ SF_{6} $, 16% $ C_{2} %$ F_{6,} $ or 12% $ C_{3} %$ F_{8} $. Eyes in group II were randomized to either 16% $ C_{2} %$ F_{6} $ or 12% $ C_{3} %$ F_{8} $. Clinical details, MH parameters on optical coherence tomography, surgical details and complications were analyzed. Outcome measures were type of hole closure (I/II), best corrected visual acuity, intraocular pressure, and cataract progression. Results In Group I (n = 139), type 1 closure was achieved in 107 (77%) eyes. Type 1 closure rates in group I per gas tamponade were as follows: $ SF_{6} $ (70%), $ C_{2} %$ F_{6} $ (80%), $ C_{3} %$ F_{8} $ (78%) (p = 0.503, chi-square test for independence). There was no statistical difference in MH closure rates between $ SF_{6} $ and $ C_{2} %$ F_{6} $ (p = 0.134), $ SF_{6} $ and $ C_{3} %$ F_{8} $ (p = 0.186), and $ C_{2} %$ F_{6} $ and $ C_{3} %$ F_{8} $ (p = 0.373). In Group II (n = 20), type 1 closure was achieved in 12 (60%) eyes. Type 1 closure rates in group II per gas tamponade were as follows: $ C_{2} %$ F_{6} $ (75%), $ C_{3} %$ F_{8} $ (50%) (p = 0.132, Two proportion Z test). Mean follow-up after surgery was 2.66 ± 2.74 months. Conclusion Given the similar outcomes of using 18% $ SF_{6} $, 16% $ C_{2} %$ F_{6,} $ or 12% $ C_{3} %$ F_{8} $ in idiopathic macular hole surgery, the advantage of using a shorter acting tamponade translates into earlier recovery and rehabilitation. Ausführliche Beschreibung

Gespeichert in:

Autor*in:	Rishi, Pukhraj [verfasserIn] Rishi, Ekta Bhende, Pramod Bhende, Muna Kandle, Kaustubh Attiku, Yamini Roy, Krishna Kanta Shelke, Komal Madaan, Sushant

Format:	E-Artikel
Sprache:	Englisch

Erschienen:	2022

Schlagwörter:	Macular hole Surgery Gas Hole closure

Anmerkung:	© The Author(s), under exclusive licence to Springer Nature B.V. 2021

Übergeordnetes Werk:	Enthalten in: International ophthalmology - Dordrecht : Springer Science + Business Media B.V., 1978, 42(2022), 5 vom: 08. Jan., Seite 1515-1521
Übergeordnetes Werk:	volume:42 ; year:2022 ; number:5 ; day:08 ; month:01 ; pages:1515-1521

Links:	Volltext

DOI / URN:	10.1007/s10792-021-02141-0

Katalog-ID:	SPR04705767X

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245	1	2	\|a A prospective, interventional study comparing the outcomes of macular hole surgery in eyes randomized to $ C_{3} %$ F_{8} $, $ C_{2} %$ F_{6,} $ or $ SF_{6} $ gas tamponade
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520			\|a Purpose Analysis of outcomes of macular hole (MH) surgery using 12% $ C_{3} %$ F_{8} $, 16% $ C_{2} %$ F_{6} $, or 18% $ SF_{6} $ as randomized gas tamponading agent. Methods This is a prospective, randomized, interventional study of 159 eyes with idiopathic MH undergoing 23/25G pars-plana vitrectomy with internal limiting membrane peeling and gas tamponade. Eyes were stratified into two groups: Group I (MH < 800 µ) and group II (MH > 800 µ) according to MH apical diameter. Eyes in group I were randomized to receive either 18% $ SF_{6} $, 16% $ C_{2} %$ F_{6,} $ or 12% $ C_{3} %$ F_{8} $. Eyes in group II were randomized to either 16% $ C_{2} %$ F_{6} $ or 12% $ C_{3} %$ F_{8} $. Clinical details, MH parameters on optical coherence tomography, surgical details and complications were analyzed. Outcome measures were type of hole closure (I/II), best corrected visual acuity, intraocular pressure, and cataract progression. Results In Group I (n = 139), type 1 closure was achieved in 107 (77%) eyes. Type 1 closure rates in group I per gas tamponade were as follows: $ SF_{6} $ (70%), $ C_{2} %$ F_{6} $ (80%), $ C_{3} %$ F_{8} $ (78%) (p = 0.503, chi-square test for independence). There was no statistical difference in MH closure rates between $ SF_{6} $ and $ C_{2} %$ F_{6} $ (p = 0.134), $ SF_{6} $ and $ C_{3} %$ F_{8} $ (p = 0.186), and $ C_{2} %$ F_{6} $ and $ C_{3} %$ F_{8} $ (p = 0.373). In Group II (n = 20), type 1 closure was achieved in 12 (60%) eyes. Type 1 closure rates in group II per gas tamponade were as follows: $ C_{2} %$ F_{6} $ (75%), $ C_{3} %$ F_{8} $ (50%) (p = 0.132, Two proportion Z test). Mean follow-up after surgery was 2.66 ± 2.74 months. Conclusion Given the similar outcomes of using 18% $ SF_{6} $, 16% $ C_{2} %$ F_{6,} $ or 12% $ C_{3} %$ F_{8} $ in idiopathic macular hole surgery, the advantage of using a shorter acting tamponade translates into earlier recovery and rehabilitation.
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publishDate	2022
allfields	10.1007/s10792-021-02141-0 doi (DE-627)SPR04705767X (SPR)s10792-021-02141-0-e DE-627 ger DE-627 rakwb eng Rishi, Pukhraj verfasserin (orcid)0000-0001-5615-7734 aut A prospective, interventional study comparing the outcomes of macular hole surgery in eyes randomized to $ C_{3} %$ F_{8} $, $ C_{2} %$ F_{6,} $ or $ SF_{6} $ gas tamponade 2022 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier © The Author(s), under exclusive licence to Springer Nature B.V. 2021 Purpose Analysis of outcomes of macular hole (MH) surgery using 12% $ C_{3} %$ F_{8} $, 16% $ C_{2} %$ F_{6} $, or 18% $ SF_{6} $ as randomized gas tamponading agent. Methods This is a prospective, randomized, interventional study of 159 eyes with idiopathic MH undergoing 23/25G pars-plana vitrectomy with internal limiting membrane peeling and gas tamponade. Eyes were stratified into two groups: Group I (MH < 800 µ) and group II (MH > 800 µ) according to MH apical diameter. Eyes in group I were randomized to receive either 18% $ SF_{6} $, 16% $ C_{2} %$ F_{6,} $ or 12% $ C_{3} %$ F_{8} $. Eyes in group II were randomized to either 16% $ C_{2} %$ F_{6} $ or 12% $ C_{3} %$ F_{8} $. Clinical details, MH parameters on optical coherence tomography, surgical details and complications were analyzed. Outcome measures were type of hole closure (I/II), best corrected visual acuity, intraocular pressure, and cataract progression. Results In Group I (n = 139), type 1 closure was achieved in 107 (77%) eyes. Type 1 closure rates in group I per gas tamponade were as follows: $ SF_{6} $ (70%), $ C_{2} %$ F_{6} $ (80%), $ C_{3} %$ F_{8} $ (78%) (p = 0.503, chi-square test for independence). There was no statistical difference in MH closure rates between $ SF_{6} $ and $ C_{2} %$ F_{6} $ (p = 0.134), $ SF_{6} $ and $ C_{3} %$ F_{8} $ (p = 0.186), and $ C_{2} %$ F_{6} $ and $ C_{3} %$ F_{8} $ (p = 0.373). In Group II (n = 20), type 1 closure was achieved in 12 (60%) eyes. Type 1 closure rates in group II per gas tamponade were as follows: $ C_{2} %$ F_{6} $ (75%), $ C_{3} %$ F_{8} $ (50%) (p = 0.132, Two proportion Z test). Mean follow-up after surgery was 2.66 ± 2.74 months. Conclusion Given the similar outcomes of using 18% $ SF_{6} $, 16% $ C_{2} %$ F_{6,} $ or 12% $ C_{3} %$ F_{8} $ in idiopathic macular hole surgery, the advantage of using a shorter acting tamponade translates into earlier recovery and rehabilitation. Macular hole (dpeaa)DE-He213 Surgery (dpeaa)DE-He213 Gas (dpeaa)DE-He213 Hole closure (dpeaa)DE-He213 Rishi, Ekta aut Bhende, Pramod aut Bhende, Muna aut Kandle, Kaustubh aut Attiku, Yamini aut Roy, Krishna Kanta aut Shelke, Komal aut Madaan, Sushant aut Enthalten in International ophthalmology Dordrecht : Springer Science + Business Media B.V., 1978 42(2022), 5 vom: 08. Jan., Seite 1515-1521 (DE-627)320481131 (DE-600)2009810-8 1573-2630 nnns volume:42 year:2022 number:5 day:08 month:01 pages:1515-1521 https://dx.doi.org/10.1007/s10792-021-02141-0 lizenzpflichtig Volltext GBV_USEFLAG_A SYSFLAG_A GBV_SPRINGER GBV_ILN_11 GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_32 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_69 GBV_ILN_70 GBV_ILN_73 GBV_ILN_74 GBV_ILN_90 GBV_ILN_95 GBV_ILN_100 GBV_ILN_101 GBV_ILN_105 GBV_ILN_110 GBV_ILN_120 GBV_ILN_138 GBV_ILN_150 GBV_ILN_151 GBV_ILN_152 GBV_ILN_161 GBV_ILN_170 GBV_ILN_171 GBV_ILN_187 GBV_ILN_213 GBV_ILN_224 GBV_ILN_230 GBV_ILN_250 GBV_ILN_281 GBV_ILN_285 GBV_ILN_293 GBV_ILN_370 GBV_ILN_602 GBV_ILN_636 GBV_ILN_702 GBV_ILN_711 GBV_ILN_2001 GBV_ILN_2003 GBV_ILN_2004 GBV_ILN_2005 GBV_ILN_2006 GBV_ILN_2007 GBV_ILN_2008 GBV_ILN_2009 GBV_ILN_2010 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2015 GBV_ILN_2020 GBV_ILN_2021 GBV_ILN_2025 GBV_ILN_2026 GBV_ILN_2027 GBV_ILN_2031 GBV_ILN_2034 GBV_ILN_2037 GBV_ILN_2038 GBV_ILN_2039 GBV_ILN_2044 GBV_ILN_2048 GBV_ILN_2049 GBV_ILN_2050 GBV_ILN_2055 GBV_ILN_2056 GBV_ILN_2057 GBV_ILN_2059 GBV_ILN_2061 GBV_ILN_2064 GBV_ILN_2065 GBV_ILN_2068 GBV_ILN_2088 GBV_ILN_2093 GBV_ILN_2106 GBV_ILN_2107 GBV_ILN_2108 GBV_ILN_2110 GBV_ILN_2111 GBV_ILN_2112 GBV_ILN_2113 GBV_ILN_2118 GBV_ILN_2122 GBV_ILN_2129 GBV_ILN_2143 GBV_ILN_2144 GBV_ILN_2147 GBV_ILN_2148 GBV_ILN_2152 GBV_ILN_2153 GBV_ILN_2188 GBV_ILN_2190 GBV_ILN_2232 GBV_ILN_2336 GBV_ILN_2446 GBV_ILN_2470 GBV_ILN_2472 GBV_ILN_2507 GBV_ILN_2522 GBV_ILN_2548 GBV_ILN_4035 GBV_ILN_4037 GBV_ILN_4046 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4242 GBV_ILN_4246 GBV_ILN_4249 GBV_ILN_4251 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4326 GBV_ILN_4328 GBV_ILN_4333 GBV_ILN_4334 GBV_ILN_4335 GBV_ILN_4336 GBV_ILN_4338 GBV_ILN_4393 GBV_ILN_4700 AR 42 2022 5 08 01 1515-1521
spelling	10.1007/s10792-021-02141-0 doi (DE-627)SPR04705767X (SPR)s10792-021-02141-0-e DE-627 ger DE-627 rakwb eng Rishi, Pukhraj verfasserin (orcid)0000-0001-5615-7734 aut A prospective, interventional study comparing the outcomes of macular hole surgery in eyes randomized to $ C_{3} %$ F_{8} $, $ C_{2} %$ F_{6,} $ or $ SF_{6} $ gas tamponade 2022 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier © The Author(s), under exclusive licence to Springer Nature B.V. 2021 Purpose Analysis of outcomes of macular hole (MH) surgery using 12% $ C_{3} %$ F_{8} $, 16% $ C_{2} %$ F_{6} $, or 18% $ SF_{6} $ as randomized gas tamponading agent. Methods This is a prospective, randomized, interventional study of 159 eyes with idiopathic MH undergoing 23/25G pars-plana vitrectomy with internal limiting membrane peeling and gas tamponade. Eyes were stratified into two groups: Group I (MH < 800 µ) and group II (MH > 800 µ) according to MH apical diameter. Eyes in group I were randomized to receive either 18% $ SF_{6} $, 16% $ C_{2} %$ F_{6,} $ or 12% $ C_{3} %$ F_{8} $. Eyes in group II were randomized to either 16% $ C_{2} %$ F_{6} $ or 12% $ C_{3} %$ F_{8} $. Clinical details, MH parameters on optical coherence tomography, surgical details and complications were analyzed. Outcome measures were type of hole closure (I/II), best corrected visual acuity, intraocular pressure, and cataract progression. Results In Group I (n = 139), type 1 closure was achieved in 107 (77%) eyes. Type 1 closure rates in group I per gas tamponade were as follows: $ SF_{6} $ (70%), $ C_{2} %$ F_{6} $ (80%), $ C_{3} %$ F_{8} $ (78%) (p = 0.503, chi-square test for independence). There was no statistical difference in MH closure rates between $ SF_{6} $ and $ C_{2} %$ F_{6} $ (p = 0.134), $ SF_{6} $ and $ C_{3} %$ F_{8} $ (p = 0.186), and $ C_{2} %$ F_{6} $ and $ C_{3} %$ F_{8} $ (p = 0.373). In Group II (n = 20), type 1 closure was achieved in 12 (60%) eyes. Type 1 closure rates in group II per gas tamponade were as follows: $ C_{2} %$ F_{6} $ (75%), $ C_{3} %$ F_{8} $ (50%) (p = 0.132, Two proportion Z test). Mean follow-up after surgery was 2.66 ± 2.74 months. Conclusion Given the similar outcomes of using 18% $ SF_{6} $, 16% $ C_{2} %$ F_{6,} $ or 12% $ C_{3} %$ F_{8} $ in idiopathic macular hole surgery, the advantage of using a shorter acting tamponade translates into earlier recovery and rehabilitation. Macular hole (dpeaa)DE-He213 Surgery (dpeaa)DE-He213 Gas (dpeaa)DE-He213 Hole closure (dpeaa)DE-He213 Rishi, Ekta aut Bhende, Pramod aut Bhende, Muna aut Kandle, Kaustubh aut Attiku, Yamini aut Roy, Krishna Kanta aut Shelke, Komal aut Madaan, Sushant aut Enthalten in International ophthalmology Dordrecht : Springer Science + Business Media B.V., 1978 42(2022), 5 vom: 08. Jan., Seite 1515-1521 (DE-627)320481131 (DE-600)2009810-8 1573-2630 nnns volume:42 year:2022 number:5 day:08 month:01 pages:1515-1521 https://dx.doi.org/10.1007/s10792-021-02141-0 lizenzpflichtig Volltext GBV_USEFLAG_A SYSFLAG_A GBV_SPRINGER GBV_ILN_11 GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_32 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_69 GBV_ILN_70 GBV_ILN_73 GBV_ILN_74 GBV_ILN_90 GBV_ILN_95 GBV_ILN_100 GBV_ILN_101 GBV_ILN_105 GBV_ILN_110 GBV_ILN_120 GBV_ILN_138 GBV_ILN_150 GBV_ILN_151 GBV_ILN_152 GBV_ILN_161 GBV_ILN_170 GBV_ILN_171 GBV_ILN_187 GBV_ILN_213 GBV_ILN_224 GBV_ILN_230 GBV_ILN_250 GBV_ILN_281 GBV_ILN_285 GBV_ILN_293 GBV_ILN_370 GBV_ILN_602 GBV_ILN_636 GBV_ILN_702 GBV_ILN_711 GBV_ILN_2001 GBV_ILN_2003 GBV_ILN_2004 GBV_ILN_2005 GBV_ILN_2006 GBV_ILN_2007 GBV_ILN_2008 GBV_ILN_2009 GBV_ILN_2010 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2015 GBV_ILN_2020 GBV_ILN_2021 GBV_ILN_2025 GBV_ILN_2026 GBV_ILN_2027 GBV_ILN_2031 GBV_ILN_2034 GBV_ILN_2037 GBV_ILN_2038 GBV_ILN_2039 GBV_ILN_2044 GBV_ILN_2048 GBV_ILN_2049 GBV_ILN_2050 GBV_ILN_2055 GBV_ILN_2056 GBV_ILN_2057 GBV_ILN_2059 GBV_ILN_2061 GBV_ILN_2064 GBV_ILN_2065 GBV_ILN_2068 GBV_ILN_2088 GBV_ILN_2093 GBV_ILN_2106 GBV_ILN_2107 GBV_ILN_2108 GBV_ILN_2110 GBV_ILN_2111 GBV_ILN_2112 GBV_ILN_2113 GBV_ILN_2118 GBV_ILN_2122 GBV_ILN_2129 GBV_ILN_2143 GBV_ILN_2144 GBV_ILN_2147 GBV_ILN_2148 GBV_ILN_2152 GBV_ILN_2153 GBV_ILN_2188 GBV_ILN_2190 GBV_ILN_2232 GBV_ILN_2336 GBV_ILN_2446 GBV_ILN_2470 GBV_ILN_2472 GBV_ILN_2507 GBV_ILN_2522 GBV_ILN_2548 GBV_ILN_4035 GBV_ILN_4037 GBV_ILN_4046 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4242 GBV_ILN_4246 GBV_ILN_4249 GBV_ILN_4251 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4326 GBV_ILN_4328 GBV_ILN_4333 GBV_ILN_4334 GBV_ILN_4335 GBV_ILN_4336 GBV_ILN_4338 GBV_ILN_4393 GBV_ILN_4700 AR 42 2022 5 08 01 1515-1521
allfields_unstemmed	10.1007/s10792-021-02141-0 doi (DE-627)SPR04705767X (SPR)s10792-021-02141-0-e DE-627 ger DE-627 rakwb eng Rishi, Pukhraj verfasserin (orcid)0000-0001-5615-7734 aut A prospective, interventional study comparing the outcomes of macular hole surgery in eyes randomized to $ C_{3} %$ F_{8} $, $ C_{2} %$ F_{6,} $ or $ SF_{6} $ gas tamponade 2022 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier © The Author(s), under exclusive licence to Springer Nature B.V. 2021 Purpose Analysis of outcomes of macular hole (MH) surgery using 12% $ C_{3} %$ F_{8} $, 16% $ C_{2} %$ F_{6} $, or 18% $ SF_{6} $ as randomized gas tamponading agent. Methods This is a prospective, randomized, interventional study of 159 eyes with idiopathic MH undergoing 23/25G pars-plana vitrectomy with internal limiting membrane peeling and gas tamponade. Eyes were stratified into two groups: Group I (MH < 800 µ) and group II (MH > 800 µ) according to MH apical diameter. Eyes in group I were randomized to receive either 18% $ SF_{6} $, 16% $ C_{2} %$ F_{6,} $ or 12% $ C_{3} %$ F_{8} $. Eyes in group II were randomized to either 16% $ C_{2} %$ F_{6} $ or 12% $ C_{3} %$ F_{8} $. Clinical details, MH parameters on optical coherence tomography, surgical details and complications were analyzed. Outcome measures were type of hole closure (I/II), best corrected visual acuity, intraocular pressure, and cataract progression. Results In Group I (n = 139), type 1 closure was achieved in 107 (77%) eyes. Type 1 closure rates in group I per gas tamponade were as follows: $ SF_{6} $ (70%), $ C_{2} %$ F_{6} $ (80%), $ C_{3} %$ F_{8} $ (78%) (p = 0.503, chi-square test for independence). There was no statistical difference in MH closure rates between $ SF_{6} $ and $ C_{2} %$ F_{6} $ (p = 0.134), $ SF_{6} $ and $ C_{3} %$ F_{8} $ (p = 0.186), and $ C_{2} %$ F_{6} $ and $ C_{3} %$ F_{8} $ (p = 0.373). In Group II (n = 20), type 1 closure was achieved in 12 (60%) eyes. Type 1 closure rates in group II per gas tamponade were as follows: $ C_{2} %$ F_{6} $ (75%), $ C_{3} %$ F_{8} $ (50%) (p = 0.132, Two proportion Z test). Mean follow-up after surgery was 2.66 ± 2.74 months. Conclusion Given the similar outcomes of using 18% $ SF_{6} $, 16% $ C_{2} %$ F_{6,} $ or 12% $ C_{3} %$ F_{8} $ in idiopathic macular hole surgery, the advantage of using a shorter acting tamponade translates into earlier recovery and rehabilitation. Macular hole (dpeaa)DE-He213 Surgery (dpeaa)DE-He213 Gas (dpeaa)DE-He213 Hole closure (dpeaa)DE-He213 Rishi, Ekta aut Bhende, Pramod aut Bhende, Muna aut Kandle, Kaustubh aut Attiku, Yamini aut Roy, Krishna Kanta aut Shelke, Komal aut Madaan, Sushant aut Enthalten in International ophthalmology Dordrecht : Springer Science + Business Media B.V., 1978 42(2022), 5 vom: 08. Jan., Seite 1515-1521 (DE-627)320481131 (DE-600)2009810-8 1573-2630 nnns volume:42 year:2022 number:5 day:08 month:01 pages:1515-1521 https://dx.doi.org/10.1007/s10792-021-02141-0 lizenzpflichtig Volltext GBV_USEFLAG_A SYSFLAG_A GBV_SPRINGER GBV_ILN_11 GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_32 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_69 GBV_ILN_70 GBV_ILN_73 GBV_ILN_74 GBV_ILN_90 GBV_ILN_95 GBV_ILN_100 GBV_ILN_101 GBV_ILN_105 GBV_ILN_110 GBV_ILN_120 GBV_ILN_138 GBV_ILN_150 GBV_ILN_151 GBV_ILN_152 GBV_ILN_161 GBV_ILN_170 GBV_ILN_171 GBV_ILN_187 GBV_ILN_213 GBV_ILN_224 GBV_ILN_230 GBV_ILN_250 GBV_ILN_281 GBV_ILN_285 GBV_ILN_293 GBV_ILN_370 GBV_ILN_602 GBV_ILN_636 GBV_ILN_702 GBV_ILN_711 GBV_ILN_2001 GBV_ILN_2003 GBV_ILN_2004 GBV_ILN_2005 GBV_ILN_2006 GBV_ILN_2007 GBV_ILN_2008 GBV_ILN_2009 GBV_ILN_2010 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2015 GBV_ILN_2020 GBV_ILN_2021 GBV_ILN_2025 GBV_ILN_2026 GBV_ILN_2027 GBV_ILN_2031 GBV_ILN_2034 GBV_ILN_2037 GBV_ILN_2038 GBV_ILN_2039 GBV_ILN_2044 GBV_ILN_2048 GBV_ILN_2049 GBV_ILN_2050 GBV_ILN_2055 GBV_ILN_2056 GBV_ILN_2057 GBV_ILN_2059 GBV_ILN_2061 GBV_ILN_2064 GBV_ILN_2065 GBV_ILN_2068 GBV_ILN_2088 GBV_ILN_2093 GBV_ILN_2106 GBV_ILN_2107 GBV_ILN_2108 GBV_ILN_2110 GBV_ILN_2111 GBV_ILN_2112 GBV_ILN_2113 GBV_ILN_2118 GBV_ILN_2122 GBV_ILN_2129 GBV_ILN_2143 GBV_ILN_2144 GBV_ILN_2147 GBV_ILN_2148 GBV_ILN_2152 GBV_ILN_2153 GBV_ILN_2188 GBV_ILN_2190 GBV_ILN_2232 GBV_ILN_2336 GBV_ILN_2446 GBV_ILN_2470 GBV_ILN_2472 GBV_ILN_2507 GBV_ILN_2522 GBV_ILN_2548 GBV_ILN_4035 GBV_ILN_4037 GBV_ILN_4046 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4242 GBV_ILN_4246 GBV_ILN_4249 GBV_ILN_4251 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4326 GBV_ILN_4328 GBV_ILN_4333 GBV_ILN_4334 GBV_ILN_4335 GBV_ILN_4336 GBV_ILN_4338 GBV_ILN_4393 GBV_ILN_4700 AR 42 2022 5 08 01 1515-1521
allfieldsGer	10.1007/s10792-021-02141-0 doi (DE-627)SPR04705767X (SPR)s10792-021-02141-0-e DE-627 ger DE-627 rakwb eng Rishi, Pukhraj verfasserin (orcid)0000-0001-5615-7734 aut A prospective, interventional study comparing the outcomes of macular hole surgery in eyes randomized to $ C_{3} %$ F_{8} $, $ C_{2} %$ F_{6,} $ or $ SF_{6} $ gas tamponade 2022 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier © The Author(s), under exclusive licence to Springer Nature B.V. 2021 Purpose Analysis of outcomes of macular hole (MH) surgery using 12% $ C_{3} %$ F_{8} $, 16% $ C_{2} %$ F_{6} $, or 18% $ SF_{6} $ as randomized gas tamponading agent. Methods This is a prospective, randomized, interventional study of 159 eyes with idiopathic MH undergoing 23/25G pars-plana vitrectomy with internal limiting membrane peeling and gas tamponade. Eyes were stratified into two groups: Group I (MH < 800 µ) and group II (MH > 800 µ) according to MH apical diameter. Eyes in group I were randomized to receive either 18% $ SF_{6} $, 16% $ C_{2} %$ F_{6,} $ or 12% $ C_{3} %$ F_{8} $. Eyes in group II were randomized to either 16% $ C_{2} %$ F_{6} $ or 12% $ C_{3} %$ F_{8} $. Clinical details, MH parameters on optical coherence tomography, surgical details and complications were analyzed. Outcome measures were type of hole closure (I/II), best corrected visual acuity, intraocular pressure, and cataract progression. Results In Group I (n = 139), type 1 closure was achieved in 107 (77%) eyes. Type 1 closure rates in group I per gas tamponade were as follows: $ SF_{6} $ (70%), $ C_{2} %$ F_{6} $ (80%), $ C_{3} %$ F_{8} $ (78%) (p = 0.503, chi-square test for independence). There was no statistical difference in MH closure rates between $ SF_{6} $ and $ C_{2} %$ F_{6} $ (p = 0.134), $ SF_{6} $ and $ C_{3} %$ F_{8} $ (p = 0.186), and $ C_{2} %$ F_{6} $ and $ C_{3} %$ F_{8} $ (p = 0.373). In Group II (n = 20), type 1 closure was achieved in 12 (60%) eyes. Type 1 closure rates in group II per gas tamponade were as follows: $ C_{2} %$ F_{6} $ (75%), $ C_{3} %$ F_{8} $ (50%) (p = 0.132, Two proportion Z test). Mean follow-up after surgery was 2.66 ± 2.74 months. Conclusion Given the similar outcomes of using 18% $ SF_{6} $, 16% $ C_{2} %$ F_{6,} $ or 12% $ C_{3} %$ F_{8} $ in idiopathic macular hole surgery, the advantage of using a shorter acting tamponade translates into earlier recovery and rehabilitation. Macular hole (dpeaa)DE-He213 Surgery (dpeaa)DE-He213 Gas (dpeaa)DE-He213 Hole closure (dpeaa)DE-He213 Rishi, Ekta aut Bhende, Pramod aut Bhende, Muna aut Kandle, Kaustubh aut Attiku, Yamini aut Roy, Krishna Kanta aut Shelke, Komal aut Madaan, Sushant aut Enthalten in International ophthalmology Dordrecht : Springer Science + Business Media B.V., 1978 42(2022), 5 vom: 08. Jan., Seite 1515-1521 (DE-627)320481131 (DE-600)2009810-8 1573-2630 nnns volume:42 year:2022 number:5 day:08 month:01 pages:1515-1521 https://dx.doi.org/10.1007/s10792-021-02141-0 lizenzpflichtig Volltext GBV_USEFLAG_A SYSFLAG_A GBV_SPRINGER GBV_ILN_11 GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_32 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_69 GBV_ILN_70 GBV_ILN_73 GBV_ILN_74 GBV_ILN_90 GBV_ILN_95 GBV_ILN_100 GBV_ILN_101 GBV_ILN_105 GBV_ILN_110 GBV_ILN_120 GBV_ILN_138 GBV_ILN_150 GBV_ILN_151 GBV_ILN_152 GBV_ILN_161 GBV_ILN_170 GBV_ILN_171 GBV_ILN_187 GBV_ILN_213 GBV_ILN_224 GBV_ILN_230 GBV_ILN_250 GBV_ILN_281 GBV_ILN_285 GBV_ILN_293 GBV_ILN_370 GBV_ILN_602 GBV_ILN_636 GBV_ILN_702 GBV_ILN_711 GBV_ILN_2001 GBV_ILN_2003 GBV_ILN_2004 GBV_ILN_2005 GBV_ILN_2006 GBV_ILN_2007 GBV_ILN_2008 GBV_ILN_2009 GBV_ILN_2010 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2015 GBV_ILN_2020 GBV_ILN_2021 GBV_ILN_2025 GBV_ILN_2026 GBV_ILN_2027 GBV_ILN_2031 GBV_ILN_2034 GBV_ILN_2037 GBV_ILN_2038 GBV_ILN_2039 GBV_ILN_2044 GBV_ILN_2048 GBV_ILN_2049 GBV_ILN_2050 GBV_ILN_2055 GBV_ILN_2056 GBV_ILN_2057 GBV_ILN_2059 GBV_ILN_2061 GBV_ILN_2064 GBV_ILN_2065 GBV_ILN_2068 GBV_ILN_2088 GBV_ILN_2093 GBV_ILN_2106 GBV_ILN_2107 GBV_ILN_2108 GBV_ILN_2110 GBV_ILN_2111 GBV_ILN_2112 GBV_ILN_2113 GBV_ILN_2118 GBV_ILN_2122 GBV_ILN_2129 GBV_ILN_2143 GBV_ILN_2144 GBV_ILN_2147 GBV_ILN_2148 GBV_ILN_2152 GBV_ILN_2153 GBV_ILN_2188 GBV_ILN_2190 GBV_ILN_2232 GBV_ILN_2336 GBV_ILN_2446 GBV_ILN_2470 GBV_ILN_2472 GBV_ILN_2507 GBV_ILN_2522 GBV_ILN_2548 GBV_ILN_4035 GBV_ILN_4037 GBV_ILN_4046 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4242 GBV_ILN_4246 GBV_ILN_4249 GBV_ILN_4251 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4326 GBV_ILN_4328 GBV_ILN_4333 GBV_ILN_4334 GBV_ILN_4335 GBV_ILN_4336 GBV_ILN_4338 GBV_ILN_4393 GBV_ILN_4700 AR 42 2022 5 08 01 1515-1521
allfieldsSound	10.1007/s10792-021-02141-0 doi (DE-627)SPR04705767X (SPR)s10792-021-02141-0-e DE-627 ger DE-627 rakwb eng Rishi, Pukhraj verfasserin (orcid)0000-0001-5615-7734 aut A prospective, interventional study comparing the outcomes of macular hole surgery in eyes randomized to $ C_{3} %$ F_{8} $, $ C_{2} %$ F_{6,} $ or $ SF_{6} $ gas tamponade 2022 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier © The Author(s), under exclusive licence to Springer Nature B.V. 2021 Purpose Analysis of outcomes of macular hole (MH) surgery using 12% $ C_{3} %$ F_{8} $, 16% $ C_{2} %$ F_{6} $, or 18% $ SF_{6} $ as randomized gas tamponading agent. Methods This is a prospective, randomized, interventional study of 159 eyes with idiopathic MH undergoing 23/25G pars-plana vitrectomy with internal limiting membrane peeling and gas tamponade. Eyes were stratified into two groups: Group I (MH < 800 µ) and group II (MH > 800 µ) according to MH apical diameter. Eyes in group I were randomized to receive either 18% $ SF_{6} $, 16% $ C_{2} %$ F_{6,} $ or 12% $ C_{3} %$ F_{8} $. Eyes in group II were randomized to either 16% $ C_{2} %$ F_{6} $ or 12% $ C_{3} %$ F_{8} $. Clinical details, MH parameters on optical coherence tomography, surgical details and complications were analyzed. Outcome measures were type of hole closure (I/II), best corrected visual acuity, intraocular pressure, and cataract progression. Results In Group I (n = 139), type 1 closure was achieved in 107 (77%) eyes. Type 1 closure rates in group I per gas tamponade were as follows: $ SF_{6} $ (70%), $ C_{2} %$ F_{6} $ (80%), $ C_{3} %$ F_{8} $ (78%) (p = 0.503, chi-square test for independence). There was no statistical difference in MH closure rates between $ SF_{6} $ and $ C_{2} %$ F_{6} $ (p = 0.134), $ SF_{6} $ and $ C_{3} %$ F_{8} $ (p = 0.186), and $ C_{2} %$ F_{6} $ and $ C_{3} %$ F_{8} $ (p = 0.373). In Group II (n = 20), type 1 closure was achieved in 12 (60%) eyes. Type 1 closure rates in group II per gas tamponade were as follows: $ C_{2} %$ F_{6} $ (75%), $ C_{3} %$ F_{8} $ (50%) (p = 0.132, Two proportion Z test). Mean follow-up after surgery was 2.66 ± 2.74 months. Conclusion Given the similar outcomes of using 18% $ SF_{6} $, 16% $ C_{2} %$ F_{6,} $ or 12% $ C_{3} %$ F_{8} $ in idiopathic macular hole surgery, the advantage of using a shorter acting tamponade translates into earlier recovery and rehabilitation. Macular hole (dpeaa)DE-He213 Surgery (dpeaa)DE-He213 Gas (dpeaa)DE-He213 Hole closure (dpeaa)DE-He213 Rishi, Ekta aut Bhende, Pramod aut Bhende, Muna aut Kandle, Kaustubh aut Attiku, Yamini aut Roy, Krishna Kanta aut Shelke, Komal aut Madaan, Sushant aut Enthalten in International ophthalmology Dordrecht : Springer Science + Business Media B.V., 1978 42(2022), 5 vom: 08. Jan., Seite 1515-1521 (DE-627)320481131 (DE-600)2009810-8 1573-2630 nnns volume:42 year:2022 number:5 day:08 month:01 pages:1515-1521 https://dx.doi.org/10.1007/s10792-021-02141-0 lizenzpflichtig Volltext GBV_USEFLAG_A SYSFLAG_A GBV_SPRINGER GBV_ILN_11 GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_32 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_69 GBV_ILN_70 GBV_ILN_73 GBV_ILN_74 GBV_ILN_90 GBV_ILN_95 GBV_ILN_100 GBV_ILN_101 GBV_ILN_105 GBV_ILN_110 GBV_ILN_120 GBV_ILN_138 GBV_ILN_150 GBV_ILN_151 GBV_ILN_152 GBV_ILN_161 GBV_ILN_170 GBV_ILN_171 GBV_ILN_187 GBV_ILN_213 GBV_ILN_224 GBV_ILN_230 GBV_ILN_250 GBV_ILN_281 GBV_ILN_285 GBV_ILN_293 GBV_ILN_370 GBV_ILN_602 GBV_ILN_636 GBV_ILN_702 GBV_ILN_711 GBV_ILN_2001 GBV_ILN_2003 GBV_ILN_2004 GBV_ILN_2005 GBV_ILN_2006 GBV_ILN_2007 GBV_ILN_2008 GBV_ILN_2009 GBV_ILN_2010 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2015 GBV_ILN_2020 GBV_ILN_2021 GBV_ILN_2025 GBV_ILN_2026 GBV_ILN_2027 GBV_ILN_2031 GBV_ILN_2034 GBV_ILN_2037 GBV_ILN_2038 GBV_ILN_2039 GBV_ILN_2044 GBV_ILN_2048 GBV_ILN_2049 GBV_ILN_2050 GBV_ILN_2055 GBV_ILN_2056 GBV_ILN_2057 GBV_ILN_2059 GBV_ILN_2061 GBV_ILN_2064 GBV_ILN_2065 GBV_ILN_2068 GBV_ILN_2088 GBV_ILN_2093 GBV_ILN_2106 GBV_ILN_2107 GBV_ILN_2108 GBV_ILN_2110 GBV_ILN_2111 GBV_ILN_2112 GBV_ILN_2113 GBV_ILN_2118 GBV_ILN_2122 GBV_ILN_2129 GBV_ILN_2143 GBV_ILN_2144 GBV_ILN_2147 GBV_ILN_2148 GBV_ILN_2152 GBV_ILN_2153 GBV_ILN_2188 GBV_ILN_2190 GBV_ILN_2232 GBV_ILN_2336 GBV_ILN_2446 GBV_ILN_2470 GBV_ILN_2472 GBV_ILN_2507 GBV_ILN_2522 GBV_ILN_2548 GBV_ILN_4035 GBV_ILN_4037 GBV_ILN_4046 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4242 GBV_ILN_4246 GBV_ILN_4249 GBV_ILN_4251 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4326 GBV_ILN_4328 GBV_ILN_4333 GBV_ILN_4334 GBV_ILN_4335 GBV_ILN_4336 GBV_ILN_4338 GBV_ILN_4393 GBV_ILN_4700 AR 42 2022 5 08 01 1515-1521
language	English
source	Enthalten in International ophthalmology 42(2022), 5 vom: 08. Jan., Seite 1515-1521 volume:42 year:2022 number:5 day:08 month:01 pages:1515-1521
sourceStr	Enthalten in International ophthalmology 42(2022), 5 vom: 08. Jan., Seite 1515-1521 volume:42 year:2022 number:5 day:08 month:01 pages:1515-1521
format_phy_str_mv	Article
institution	findex.gbv.de
topic_facet	Macular hole Surgery Gas Hole closure
isfreeaccess_bool	false
container_title	International ophthalmology
authorswithroles_txt_mv	Rishi, Pukhraj @@aut@@ Rishi, Ekta @@aut@@ Bhende, Pramod @@aut@@ Bhende, Muna @@aut@@ Kandle, Kaustubh @@aut@@ Attiku, Yamini @@aut@@ Roy, Krishna Kanta @@aut@@ Shelke, Komal @@aut@@ Madaan, Sushant @@aut@@
publishDateDaySort_date	2022-01-08T00:00:00Z
hierarchy_top_id	320481131
id	SPR04705767X
language_de	englisch
fullrecord	<?xml version="1.0" encoding="UTF-8"?><collection xmlns="http://www.loc.gov/MARC21/slim"><record><leader>01000caa a22002652 4500</leader><controlfield tag="001">SPR04705767X</controlfield><controlfield tag="003">DE-627</controlfield><controlfield tag="005">20230509102142.0</controlfield><controlfield tag="007">cr uuu---uuuuu</controlfield><controlfield tag="008">220521s2022 xx \|\|\|\|\|o 00\| \|\|eng c</controlfield><datafield tag="024" ind1="7" ind2=" "><subfield code="a">10.1007/s10792-021-02141-0</subfield><subfield code="2">doi</subfield></datafield><datafield tag="035" ind1=" " ind2=" "><subfield code="a">(DE-627)SPR04705767X</subfield></datafield><datafield tag="035" ind1=" " ind2=" "><subfield code="a">(SPR)s10792-021-02141-0-e</subfield></datafield><datafield tag="040" ind1=" " ind2=" "><subfield code="a">DE-627</subfield><subfield code="b">ger</subfield><subfield code="c">DE-627</subfield><subfield code="e">rakwb</subfield></datafield><datafield tag="041" ind1=" " ind2=" "><subfield code="a">eng</subfield></datafield><datafield tag="100" ind1="1" ind2=" "><subfield code="a">Rishi, Pukhraj</subfield><subfield code="e">verfasserin</subfield><subfield code="0">(orcid)0000-0001-5615-7734</subfield><subfield code="4">aut</subfield></datafield><datafield tag="245" ind1="1" ind2="2"><subfield code="a">A prospective, interventional study comparing the outcomes of macular hole surgery in eyes randomized to $ C_{3} %$ F_{8} $, $ C_{2} %$ F_{6,} $ or $ SF_{6} $ gas tamponade</subfield></datafield><datafield tag="264" ind1=" " ind2="1"><subfield code="c">2022</subfield></datafield><datafield tag="336" ind1=" " ind2=" "><subfield code="a">Text</subfield><subfield code="b">txt</subfield><subfield code="2">rdacontent</subfield></datafield><datafield tag="337" ind1=" " ind2=" "><subfield code="a">Computermedien</subfield><subfield code="b">c</subfield><subfield code="2">rdamedia</subfield></datafield><datafield tag="338" ind1=" " ind2=" "><subfield code="a">Online-Ressource</subfield><subfield code="b">cr</subfield><subfield code="2">rdacarrier</subfield></datafield><datafield tag="500" ind1=" " ind2=" "><subfield code="a">© The Author(s), under exclusive licence to Springer Nature B.V. 2021</subfield></datafield><datafield tag="520" ind1=" " ind2=" "><subfield code="a">Purpose Analysis of outcomes of macular hole (MH) surgery using 12% $ C_{3} %$ F_{8} $, 16% $ C_{2} %$ F_{6} $, or 18% $ SF_{6} $ as randomized gas tamponading agent. Methods This is a prospective, randomized, interventional study of 159 eyes with idiopathic MH undergoing 23/25G pars-plana vitrectomy with internal limiting membrane peeling and gas tamponade. Eyes were stratified into two groups: Group I (MH < 800 µ) and group II (MH > 800 µ) according to MH apical diameter. Eyes in group I were randomized to receive either 18% $ SF_{6} $, 16% $ C_{2} %$ F_{6,} $ or 12% $ C_{3} %$ F_{8} $. Eyes in group II were randomized to either 16% $ C_{2} %$ F_{6} $ or 12% $ C_{3} %$ F_{8} $. Clinical details, MH parameters on optical coherence tomography, surgical details and complications were analyzed. Outcome measures were type of hole closure (I/II), best corrected visual acuity, intraocular pressure, and cataract progression. Results In Group I (n = 139), type 1 closure was achieved in 107 (77%) eyes. Type 1 closure rates in group I per gas tamponade were as follows: $ SF_{6} $ (70%), $ C_{2} %$ F_{6} $ (80%), $ C_{3} %$ F_{8} $ (78%) (p = 0.503, chi-square test for independence). There was no statistical difference in MH closure rates between $ SF_{6} $ and $ C_{2} %$ F_{6} $ (p = 0.134), $ SF_{6} $ and $ C_{3} %$ F_{8} $ (p = 0.186), and $ C_{2} %$ F_{6} $ and $ C_{3} %$ F_{8} $ (p = 0.373). In Group II (n = 20), type 1 closure was achieved in 12 (60%) eyes. Type 1 closure rates in group II per gas tamponade were as follows: $ C_{2} %$ F_{6} $ (75%), $ C_{3} %$ F_{8} $ (50%) (p = 0.132, Two proportion Z test). Mean follow-up after surgery was 2.66 ± 2.74 months. 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author	Rishi, Pukhraj
spellingShingle	Rishi, Pukhraj misc Macular hole misc Surgery misc Gas misc Hole closure A prospective, interventional study comparing the outcomes of macular hole surgery in eyes randomized to $ C_{3} %$ F_{8} $, $ C_{2} %$ F_{6,} $ or $ SF_{6} $ gas tamponade
authorStr	Rishi, Pukhraj
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topic_title	A prospective, interventional study comparing the outcomes of macular hole surgery in eyes randomized to $ C_{3} %$ F_{8} $, $ C_{2} %$ F_{6,} $ or $ SF_{6} $ gas tamponade Macular hole (dpeaa)DE-He213 Surgery (dpeaa)DE-He213 Gas (dpeaa)DE-He213 Hole closure (dpeaa)DE-He213
topic	misc Macular hole misc Surgery misc Gas misc Hole closure
topic_unstemmed	misc Macular hole misc Surgery misc Gas misc Hole closure
topic_browse	misc Macular hole misc Surgery misc Gas misc Hole closure
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title	A prospective, interventional study comparing the outcomes of macular hole surgery in eyes randomized to $ C_{3} %$ F_{8} $, $ C_{2} %$ F_{6,} $ or $ SF_{6} $ gas tamponade
ctrlnum	(DE-627)SPR04705767X (SPR)s10792-021-02141-0-e
title_full	A prospective, interventional study comparing the outcomes of macular hole surgery in eyes randomized to $ C_{3} %$ F_{8} $, $ C_{2} %$ F_{6,} $ or $ SF_{6} $ gas tamponade
author_sort	Rishi, Pukhraj
journal	International ophthalmology
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author_browse	Rishi, Pukhraj Rishi, Ekta Bhende, Pramod Bhende, Muna Kandle, Kaustubh Attiku, Yamini Roy, Krishna Kanta Shelke, Komal Madaan, Sushant
container_volume	42
format_se	Elektronische Aufsätze
author-letter	Rishi, Pukhraj
doi_str_mv	10.1007/s10792-021-02141-0
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title_sort	prospective, interventional study comparing the outcomes of macular hole surgery in eyes randomized to $ c_{3} %$ f_{8} $, $ c_{2} %$ f_{6,} $ or $ sf_{6} $ gas tamponade
title_auth	A prospective, interventional study comparing the outcomes of macular hole surgery in eyes randomized to $ C_{3} %$ F_{8} $, $ C_{2} %$ F_{6,} $ or $ SF_{6} $ gas tamponade
abstract	Purpose Analysis of outcomes of macular hole (MH) surgery using 12% $ C_{3} %$ F_{8} $, 16% $ C_{2} %$ F_{6} $, or 18% $ SF_{6} $ as randomized gas tamponading agent. Methods This is a prospective, randomized, interventional study of 159 eyes with idiopathic MH undergoing 23/25G pars-plana vitrectomy with internal limiting membrane peeling and gas tamponade. Eyes were stratified into two groups: Group I (MH < 800 µ) and group II (MH > 800 µ) according to MH apical diameter. Eyes in group I were randomized to receive either 18% $ SF_{6} $, 16% $ C_{2} %$ F_{6,} $ or 12% $ C_{3} %$ F_{8} $. Eyes in group II were randomized to either 16% $ C_{2} %$ F_{6} $ or 12% $ C_{3} %$ F_{8} $. Clinical details, MH parameters on optical coherence tomography, surgical details and complications were analyzed. Outcome measures were type of hole closure (I/II), best corrected visual acuity, intraocular pressure, and cataract progression. Results In Group I (n = 139), type 1 closure was achieved in 107 (77%) eyes. Type 1 closure rates in group I per gas tamponade were as follows: $ SF_{6} $ (70%), $ C_{2} %$ F_{6} $ (80%), $ C_{3} %$ F_{8} $ (78%) (p = 0.503, chi-square test for independence). There was no statistical difference in MH closure rates between $ SF_{6} $ and $ C_{2} %$ F_{6} $ (p = 0.134), $ SF_{6} $ and $ C_{3} %$ F_{8} $ (p = 0.186), and $ C_{2} %$ F_{6} $ and $ C_{3} %$ F_{8} $ (p = 0.373). In Group II (n = 20), type 1 closure was achieved in 12 (60%) eyes. Type 1 closure rates in group II per gas tamponade were as follows: $ C_{2} %$ F_{6} $ (75%), $ C_{3} %$ F_{8} $ (50%) (p = 0.132, Two proportion Z test). Mean follow-up after surgery was 2.66 ± 2.74 months. Conclusion Given the similar outcomes of using 18% $ SF_{6} $, 16% $ C_{2} %$ F_{6,} $ or 12% $ C_{3} %$ F_{8} $ in idiopathic macular hole surgery, the advantage of using a shorter acting tamponade translates into earlier recovery and rehabilitation. © The Author(s), under exclusive licence to Springer Nature B.V. 2021
abstractGer	Purpose Analysis of outcomes of macular hole (MH) surgery using 12% $ C_{3} %$ F_{8} $, 16% $ C_{2} %$ F_{6} $, or 18% $ SF_{6} $ as randomized gas tamponading agent. Methods This is a prospective, randomized, interventional study of 159 eyes with idiopathic MH undergoing 23/25G pars-plana vitrectomy with internal limiting membrane peeling and gas tamponade. Eyes were stratified into two groups: Group I (MH < 800 µ) and group II (MH > 800 µ) according to MH apical diameter. Eyes in group I were randomized to receive either 18% $ SF_{6} $, 16% $ C_{2} %$ F_{6,} $ or 12% $ C_{3} %$ F_{8} $. Eyes in group II were randomized to either 16% $ C_{2} %$ F_{6} $ or 12% $ C_{3} %$ F_{8} $. Clinical details, MH parameters on optical coherence tomography, surgical details and complications were analyzed. Outcome measures were type of hole closure (I/II), best corrected visual acuity, intraocular pressure, and cataract progression. Results In Group I (n = 139), type 1 closure was achieved in 107 (77%) eyes. Type 1 closure rates in group I per gas tamponade were as follows: $ SF_{6} $ (70%), $ C_{2} %$ F_{6} $ (80%), $ C_{3} %$ F_{8} $ (78%) (p = 0.503, chi-square test for independence). There was no statistical difference in MH closure rates between $ SF_{6} $ and $ C_{2} %$ F_{6} $ (p = 0.134), $ SF_{6} $ and $ C_{3} %$ F_{8} $ (p = 0.186), and $ C_{2} %$ F_{6} $ and $ C_{3} %$ F_{8} $ (p = 0.373). In Group II (n = 20), type 1 closure was achieved in 12 (60%) eyes. Type 1 closure rates in group II per gas tamponade were as follows: $ C_{2} %$ F_{6} $ (75%), $ C_{3} %$ F_{8} $ (50%) (p = 0.132, Two proportion Z test). Mean follow-up after surgery was 2.66 ± 2.74 months. Conclusion Given the similar outcomes of using 18% $ SF_{6} $, 16% $ C_{2} %$ F_{6,} $ or 12% $ C_{3} %$ F_{8} $ in idiopathic macular hole surgery, the advantage of using a shorter acting tamponade translates into earlier recovery and rehabilitation. © The Author(s), under exclusive licence to Springer Nature B.V. 2021
abstract_unstemmed	Purpose Analysis of outcomes of macular hole (MH) surgery using 12% $ C_{3} %$ F_{8} $, 16% $ C_{2} %$ F_{6} $, or 18% $ SF_{6} $ as randomized gas tamponading agent. Methods This is a prospective, randomized, interventional study of 159 eyes with idiopathic MH undergoing 23/25G pars-plana vitrectomy with internal limiting membrane peeling and gas tamponade. Eyes were stratified into two groups: Group I (MH < 800 µ) and group II (MH > 800 µ) according to MH apical diameter. Eyes in group I were randomized to receive either 18% $ SF_{6} $, 16% $ C_{2} %$ F_{6,} $ or 12% $ C_{3} %$ F_{8} $. Eyes in group II were randomized to either 16% $ C_{2} %$ F_{6} $ or 12% $ C_{3} %$ F_{8} $. Clinical details, MH parameters on optical coherence tomography, surgical details and complications were analyzed. Outcome measures were type of hole closure (I/II), best corrected visual acuity, intraocular pressure, and cataract progression. Results In Group I (n = 139), type 1 closure was achieved in 107 (77%) eyes. Type 1 closure rates in group I per gas tamponade were as follows: $ SF_{6} $ (70%), $ C_{2} %$ F_{6} $ (80%), $ C_{3} %$ F_{8} $ (78%) (p = 0.503, chi-square test for independence). There was no statistical difference in MH closure rates between $ SF_{6} $ and $ C_{2} %$ F_{6} $ (p = 0.134), $ SF_{6} $ and $ C_{3} %$ F_{8} $ (p = 0.186), and $ C_{2} %$ F_{6} $ and $ C_{3} %$ F_{8} $ (p = 0.373). In Group II (n = 20), type 1 closure was achieved in 12 (60%) eyes. Type 1 closure rates in group II per gas tamponade were as follows: $ C_{2} %$ F_{6} $ (75%), $ C_{3} %$ F_{8} $ (50%) (p = 0.132, Two proportion Z test). Mean follow-up after surgery was 2.66 ± 2.74 months. Conclusion Given the similar outcomes of using 18% $ SF_{6} $, 16% $ C_{2} %$ F_{6,} $ or 12% $ C_{3} %$ F_{8} $ in idiopathic macular hole surgery, the advantage of using a shorter acting tamponade translates into earlier recovery and rehabilitation. © The Author(s), under exclusive licence to Springer Nature B.V. 2021
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container_issue	5
title_short	A prospective, interventional study comparing the outcomes of macular hole surgery in eyes randomized to $ C_{3} %$ F_{8} $, $ C_{2} %$ F_{6,} $ or $ SF_{6} $ gas tamponade
url	https://dx.doi.org/10.1007/s10792-021-02141-0
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author2	Rishi, Ekta Bhende, Pramod Bhende, Muna Kandle, Kaustubh Attiku, Yamini Roy, Krishna Kanta Shelke, Komal Madaan, Sushant
author2Str	Rishi, Ekta Bhende, Pramod Bhende, Muna Kandle, Kaustubh Attiku, Yamini Roy, Krishna Kanta Shelke, Komal Madaan, Sushant
ppnlink	320481131
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doi_str	10.1007/s10792-021-02141-0
up_date	2024-07-04T01:40:46.562Z
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Methods This is a prospective, randomized, interventional study of 159 eyes with idiopathic MH undergoing 23/25G pars-plana vitrectomy with internal limiting membrane peeling and gas tamponade. Eyes were stratified into two groups: Group I (MH < 800 µ) and group II (MH > 800 µ) according to MH apical diameter. Eyes in group I were randomized to receive either 18% $ SF_{6} $, 16% $ C_{2} %$ F_{6,} $ or 12% $ C_{3} %$ F_{8} $. Eyes in group II were randomized to either 16% $ C_{2} %$ F_{6} $ or 12% $ C_{3} %$ F_{8} $. Clinical details, MH parameters on optical coherence tomography, surgical details and complications were analyzed. Outcome measures were type of hole closure (I/II), best corrected visual acuity, intraocular pressure, and cataract progression. Results In Group I (n = 139), type 1 closure was achieved in 107 (77%) eyes. 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A prospective, interventional study comparing the outcomes of macular hole surgery in eyes randomized to $ C_{3} %$ F_{8} $, $ C_{2} %$ F_{6,} $ or $ SF_{6} $ gas tamponade

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