Association between cumulus cells—mRNA levels of AMHR2 and FSHR with oocyte maturity
Background The gene expression of anti-Mullerian hormone receptor type 2 (AMHR2) and follicle stimulating hormone receptor (FSHR) in cumulus cells (CCs) isolated from mature and immature oocytes was studied as a possible non-invasive approach for determining oocyte maturity and quality. The CCs of 1...
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Gespeichert in:
| Autor*in: |
Montazeri, Fateme [verfasserIn] |
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| Format: |
E-Artikel |
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| Sprache: |
Englisch |
| Erschienen: |
2022 |
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| Schlagwörter: |
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| Anmerkung: |
© The Author(s) 2022 |
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| Übergeordnetes Werk: |
Enthalten in: Middle East Fertility Society journal - [S.l.] : Elsevier, 2004, 27(2022), 1 vom: 30. Aug. |
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| Übergeordnetes Werk: |
volume:27 ; year:2022 ; number:1 ; day:30 ; month:08 |
| Links: |
|---|
| DOI / URN: |
10.1186/s43043-022-00116-4 |
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SPR04798998X |
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| 520 | |a Background The gene expression of anti-Mullerian hormone receptor type 2 (AMHR2) and follicle stimulating hormone receptor (FSHR) in cumulus cells (CCs) isolated from mature and immature oocytes was studied as a possible non-invasive approach for determining oocyte maturity and quality. The CCs of 100 infertile women with different etiologic factors were subdivided into control (CCs from MII) and case (CCs from GV) group. Q-PCR was used to evaluate FSHR and AMHR2 mRNA expression levels in CCs from mature and immature oocytes. Results AMHR2 and FSHR genes are significantly overexpressed (4–6 fold) in CCs from immature relative to mature oocyte. The expression level of AMHR2 gene in terms of etiologic subgroups is significantly different (P value 0.000). FSHR mRNA expression levels in CCs show no significant difference regarding etiologic subgroups (P value 0.575). Conclusion It seems that determining the expression level of AMHR2 and FSHR genes in CCs could help to understanding molecular mechanism of oocyte maturation process. | ||
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| 700 | 1 | |a Kalantar, Seyed Mehdi |4 aut | |
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| 700 | 1 | |a Omidi, Marjan |4 aut | |
| 700 | 1 | |a Shafienia, Hanieh |4 aut | |
| 700 | 1 | |a Hoseini, Seyed Mehdi |4 aut | |
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10.1186/s43043-022-00116-4 doi (DE-627)SPR04798998X (SPR)s43043-022-00116-4-e DE-627 ger DE-627 rakwb eng Montazeri, Fateme verfasserin aut Association between cumulus cells—mRNA levels of AMHR2 and FSHR with oocyte maturity 2022 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier © The Author(s) 2022 Background The gene expression of anti-Mullerian hormone receptor type 2 (AMHR2) and follicle stimulating hormone receptor (FSHR) in cumulus cells (CCs) isolated from mature and immature oocytes was studied as a possible non-invasive approach for determining oocyte maturity and quality. The CCs of 100 infertile women with different etiologic factors were subdivided into control (CCs from MII) and case (CCs from GV) group. Q-PCR was used to evaluate FSHR and AMHR2 mRNA expression levels in CCs from mature and immature oocytes. Results AMHR2 and FSHR genes are significantly overexpressed (4–6 fold) in CCs from immature relative to mature oocyte. The expression level of AMHR2 gene in terms of etiologic subgroups is significantly different (P value 0.000). FSHR mRNA expression levels in CCs show no significant difference regarding etiologic subgroups (P value 0.575). Conclusion It seems that determining the expression level of AMHR2 and FSHR genes in CCs could help to understanding molecular mechanism of oocyte maturation process. Biomarker (dpeaa)DE-He213 Cumulus cells (dpeaa)DE-He213 Oocyte maturity (dpeaa)DE-He213 Kalantar, Seyed Mehdi aut Fesahat, Farzaneh aut Sheikhha, Mohammad Hasan aut Omidi, Marjan aut Shafienia, Hanieh aut Hoseini, Seyed Mehdi aut Enthalten in Middle East Fertility Society journal [S.l.] : Elsevier, 2004 27(2022), 1 vom: 30. Aug. (DE-627)494831642 (DE-600)2196955-3 2090-3251 nnns volume:27 year:2022 number:1 day:30 month:08 https://dx.doi.org/10.1186/s43043-022-00116-4 kostenfrei Volltext GBV_USEFLAG_A SYSFLAG_A GBV_SPRINGER GBV_ILN_206 GBV_ILN_2004 GBV_ILN_2005 GBV_ILN_2009 GBV_ILN_2011 GBV_ILN_2055 GBV_ILN_2111 GBV_ILN_4305 AR 27 2022 1 30 08 |
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10.1186/s43043-022-00116-4 doi (DE-627)SPR04798998X (SPR)s43043-022-00116-4-e DE-627 ger DE-627 rakwb eng Montazeri, Fateme verfasserin aut Association between cumulus cells—mRNA levels of AMHR2 and FSHR with oocyte maturity 2022 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier © The Author(s) 2022 Background The gene expression of anti-Mullerian hormone receptor type 2 (AMHR2) and follicle stimulating hormone receptor (FSHR) in cumulus cells (CCs) isolated from mature and immature oocytes was studied as a possible non-invasive approach for determining oocyte maturity and quality. The CCs of 100 infertile women with different etiologic factors were subdivided into control (CCs from MII) and case (CCs from GV) group. Q-PCR was used to evaluate FSHR and AMHR2 mRNA expression levels in CCs from mature and immature oocytes. Results AMHR2 and FSHR genes are significantly overexpressed (4–6 fold) in CCs from immature relative to mature oocyte. The expression level of AMHR2 gene in terms of etiologic subgroups is significantly different (P value 0.000). FSHR mRNA expression levels in CCs show no significant difference regarding etiologic subgroups (P value 0.575). Conclusion It seems that determining the expression level of AMHR2 and FSHR genes in CCs could help to understanding molecular mechanism of oocyte maturation process. Biomarker (dpeaa)DE-He213 Cumulus cells (dpeaa)DE-He213 Oocyte maturity (dpeaa)DE-He213 Kalantar, Seyed Mehdi aut Fesahat, Farzaneh aut Sheikhha, Mohammad Hasan aut Omidi, Marjan aut Shafienia, Hanieh aut Hoseini, Seyed Mehdi aut Enthalten in Middle East Fertility Society journal [S.l.] : Elsevier, 2004 27(2022), 1 vom: 30. Aug. (DE-627)494831642 (DE-600)2196955-3 2090-3251 nnns volume:27 year:2022 number:1 day:30 month:08 https://dx.doi.org/10.1186/s43043-022-00116-4 kostenfrei Volltext GBV_USEFLAG_A SYSFLAG_A GBV_SPRINGER GBV_ILN_206 GBV_ILN_2004 GBV_ILN_2005 GBV_ILN_2009 GBV_ILN_2011 GBV_ILN_2055 GBV_ILN_2111 GBV_ILN_4305 AR 27 2022 1 30 08 |
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10.1186/s43043-022-00116-4 doi (DE-627)SPR04798998X (SPR)s43043-022-00116-4-e DE-627 ger DE-627 rakwb eng Montazeri, Fateme verfasserin aut Association between cumulus cells—mRNA levels of AMHR2 and FSHR with oocyte maturity 2022 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier © The Author(s) 2022 Background The gene expression of anti-Mullerian hormone receptor type 2 (AMHR2) and follicle stimulating hormone receptor (FSHR) in cumulus cells (CCs) isolated from mature and immature oocytes was studied as a possible non-invasive approach for determining oocyte maturity and quality. The CCs of 100 infertile women with different etiologic factors were subdivided into control (CCs from MII) and case (CCs from GV) group. Q-PCR was used to evaluate FSHR and AMHR2 mRNA expression levels in CCs from mature and immature oocytes. Results AMHR2 and FSHR genes are significantly overexpressed (4–6 fold) in CCs from immature relative to mature oocyte. The expression level of AMHR2 gene in terms of etiologic subgroups is significantly different (P value 0.000). FSHR mRNA expression levels in CCs show no significant difference regarding etiologic subgroups (P value 0.575). Conclusion It seems that determining the expression level of AMHR2 and FSHR genes in CCs could help to understanding molecular mechanism of oocyte maturation process. Biomarker (dpeaa)DE-He213 Cumulus cells (dpeaa)DE-He213 Oocyte maturity (dpeaa)DE-He213 Kalantar, Seyed Mehdi aut Fesahat, Farzaneh aut Sheikhha, Mohammad Hasan aut Omidi, Marjan aut Shafienia, Hanieh aut Hoseini, Seyed Mehdi aut Enthalten in Middle East Fertility Society journal [S.l.] : Elsevier, 2004 27(2022), 1 vom: 30. Aug. (DE-627)494831642 (DE-600)2196955-3 2090-3251 nnns volume:27 year:2022 number:1 day:30 month:08 https://dx.doi.org/10.1186/s43043-022-00116-4 kostenfrei Volltext GBV_USEFLAG_A SYSFLAG_A GBV_SPRINGER GBV_ILN_206 GBV_ILN_2004 GBV_ILN_2005 GBV_ILN_2009 GBV_ILN_2011 GBV_ILN_2055 GBV_ILN_2111 GBV_ILN_4305 AR 27 2022 1 30 08 |
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10.1186/s43043-022-00116-4 doi (DE-627)SPR04798998X (SPR)s43043-022-00116-4-e DE-627 ger DE-627 rakwb eng Montazeri, Fateme verfasserin aut Association between cumulus cells—mRNA levels of AMHR2 and FSHR with oocyte maturity 2022 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier © The Author(s) 2022 Background The gene expression of anti-Mullerian hormone receptor type 2 (AMHR2) and follicle stimulating hormone receptor (FSHR) in cumulus cells (CCs) isolated from mature and immature oocytes was studied as a possible non-invasive approach for determining oocyte maturity and quality. The CCs of 100 infertile women with different etiologic factors were subdivided into control (CCs from MII) and case (CCs from GV) group. Q-PCR was used to evaluate FSHR and AMHR2 mRNA expression levels in CCs from mature and immature oocytes. Results AMHR2 and FSHR genes are significantly overexpressed (4–6 fold) in CCs from immature relative to mature oocyte. The expression level of AMHR2 gene in terms of etiologic subgroups is significantly different (P value 0.000). FSHR mRNA expression levels in CCs show no significant difference regarding etiologic subgroups (P value 0.575). Conclusion It seems that determining the expression level of AMHR2 and FSHR genes in CCs could help to understanding molecular mechanism of oocyte maturation process. Biomarker (dpeaa)DE-He213 Cumulus cells (dpeaa)DE-He213 Oocyte maturity (dpeaa)DE-He213 Kalantar, Seyed Mehdi aut Fesahat, Farzaneh aut Sheikhha, Mohammad Hasan aut Omidi, Marjan aut Shafienia, Hanieh aut Hoseini, Seyed Mehdi aut Enthalten in Middle East Fertility Society journal [S.l.] : Elsevier, 2004 27(2022), 1 vom: 30. Aug. (DE-627)494831642 (DE-600)2196955-3 2090-3251 nnns volume:27 year:2022 number:1 day:30 month:08 https://dx.doi.org/10.1186/s43043-022-00116-4 kostenfrei Volltext GBV_USEFLAG_A SYSFLAG_A GBV_SPRINGER GBV_ILN_206 GBV_ILN_2004 GBV_ILN_2005 GBV_ILN_2009 GBV_ILN_2011 GBV_ILN_2055 GBV_ILN_2111 GBV_ILN_4305 AR 27 2022 1 30 08 |
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10.1186/s43043-022-00116-4 doi (DE-627)SPR04798998X (SPR)s43043-022-00116-4-e DE-627 ger DE-627 rakwb eng Montazeri, Fateme verfasserin aut Association between cumulus cells—mRNA levels of AMHR2 and FSHR with oocyte maturity 2022 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier © The Author(s) 2022 Background The gene expression of anti-Mullerian hormone receptor type 2 (AMHR2) and follicle stimulating hormone receptor (FSHR) in cumulus cells (CCs) isolated from mature and immature oocytes was studied as a possible non-invasive approach for determining oocyte maturity and quality. The CCs of 100 infertile women with different etiologic factors were subdivided into control (CCs from MII) and case (CCs from GV) group. Q-PCR was used to evaluate FSHR and AMHR2 mRNA expression levels in CCs from mature and immature oocytes. Results AMHR2 and FSHR genes are significantly overexpressed (4–6 fold) in CCs from immature relative to mature oocyte. The expression level of AMHR2 gene in terms of etiologic subgroups is significantly different (P value 0.000). FSHR mRNA expression levels in CCs show no significant difference regarding etiologic subgroups (P value 0.575). Conclusion It seems that determining the expression level of AMHR2 and FSHR genes in CCs could help to understanding molecular mechanism of oocyte maturation process. Biomarker (dpeaa)DE-He213 Cumulus cells (dpeaa)DE-He213 Oocyte maturity (dpeaa)DE-He213 Kalantar, Seyed Mehdi aut Fesahat, Farzaneh aut Sheikhha, Mohammad Hasan aut Omidi, Marjan aut Shafienia, Hanieh aut Hoseini, Seyed Mehdi aut Enthalten in Middle East Fertility Society journal [S.l.] : Elsevier, 2004 27(2022), 1 vom: 30. Aug. (DE-627)494831642 (DE-600)2196955-3 2090-3251 nnns volume:27 year:2022 number:1 day:30 month:08 https://dx.doi.org/10.1186/s43043-022-00116-4 kostenfrei Volltext GBV_USEFLAG_A SYSFLAG_A GBV_SPRINGER GBV_ILN_206 GBV_ILN_2004 GBV_ILN_2005 GBV_ILN_2009 GBV_ILN_2011 GBV_ILN_2055 GBV_ILN_2111 GBV_ILN_4305 AR 27 2022 1 30 08 |
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The CCs of 100 infertile women with different etiologic factors were subdivided into control (CCs from MII) and case (CCs from GV) group. Q-PCR was used to evaluate FSHR and AMHR2 mRNA expression levels in CCs from mature and immature oocytes. Results AMHR2 and FSHR genes are significantly overexpressed (4–6 fold) in CCs from immature relative to mature oocyte. The expression level of AMHR2 gene in terms of etiologic subgroups is significantly different (P value 0.000). FSHR mRNA expression levels in CCs show no significant difference regarding etiologic subgroups (P value 0.575). 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Montazeri, Fateme Kalantar, Seyed Mehdi Fesahat, Farzaneh Sheikhha, Mohammad Hasan Omidi, Marjan Shafienia, Hanieh Hoseini, Seyed Mehdi |
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Elektronische Aufsätze |
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Montazeri, Fateme |
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10.1186/s43043-022-00116-4 |
| title_sort |
association between cumulus cells—mrna levels of amhr2 and fshr with oocyte maturity |
| title_auth |
Association between cumulus cells—mRNA levels of AMHR2 and FSHR with oocyte maturity |
| abstract |
Background The gene expression of anti-Mullerian hormone receptor type 2 (AMHR2) and follicle stimulating hormone receptor (FSHR) in cumulus cells (CCs) isolated from mature and immature oocytes was studied as a possible non-invasive approach for determining oocyte maturity and quality. The CCs of 100 infertile women with different etiologic factors were subdivided into control (CCs from MII) and case (CCs from GV) group. Q-PCR was used to evaluate FSHR and AMHR2 mRNA expression levels in CCs from mature and immature oocytes. Results AMHR2 and FSHR genes are significantly overexpressed (4–6 fold) in CCs from immature relative to mature oocyte. The expression level of AMHR2 gene in terms of etiologic subgroups is significantly different (P value 0.000). FSHR mRNA expression levels in CCs show no significant difference regarding etiologic subgroups (P value 0.575). Conclusion It seems that determining the expression level of AMHR2 and FSHR genes in CCs could help to understanding molecular mechanism of oocyte maturation process. © The Author(s) 2022 |
| abstractGer |
Background The gene expression of anti-Mullerian hormone receptor type 2 (AMHR2) and follicle stimulating hormone receptor (FSHR) in cumulus cells (CCs) isolated from mature and immature oocytes was studied as a possible non-invasive approach for determining oocyte maturity and quality. The CCs of 100 infertile women with different etiologic factors were subdivided into control (CCs from MII) and case (CCs from GV) group. Q-PCR was used to evaluate FSHR and AMHR2 mRNA expression levels in CCs from mature and immature oocytes. Results AMHR2 and FSHR genes are significantly overexpressed (4–6 fold) in CCs from immature relative to mature oocyte. The expression level of AMHR2 gene in terms of etiologic subgroups is significantly different (P value 0.000). FSHR mRNA expression levels in CCs show no significant difference regarding etiologic subgroups (P value 0.575). Conclusion It seems that determining the expression level of AMHR2 and FSHR genes in CCs could help to understanding molecular mechanism of oocyte maturation process. © The Author(s) 2022 |
| abstract_unstemmed |
Background The gene expression of anti-Mullerian hormone receptor type 2 (AMHR2) and follicle stimulating hormone receptor (FSHR) in cumulus cells (CCs) isolated from mature and immature oocytes was studied as a possible non-invasive approach for determining oocyte maturity and quality. The CCs of 100 infertile women with different etiologic factors were subdivided into control (CCs from MII) and case (CCs from GV) group. Q-PCR was used to evaluate FSHR and AMHR2 mRNA expression levels in CCs from mature and immature oocytes. Results AMHR2 and FSHR genes are significantly overexpressed (4–6 fold) in CCs from immature relative to mature oocyte. The expression level of AMHR2 gene in terms of etiologic subgroups is significantly different (P value 0.000). FSHR mRNA expression levels in CCs show no significant difference regarding etiologic subgroups (P value 0.575). Conclusion It seems that determining the expression level of AMHR2 and FSHR genes in CCs could help to understanding molecular mechanism of oocyte maturation process. © The Author(s) 2022 |
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Association between cumulus cells—mRNA levels of AMHR2 and FSHR with oocyte maturity |
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