Nanofibers for the Immunoregulation in Biomedical Applications
Despite great efforts and achievement of nanomaterials in immune-associated diseases, the selection of appropriate nanomaterials and preparation technology remain some challenges and vast room for improvement. Immunotherapy has received tremendous attention throughout the medical process due to its...
Ausführliche Beschreibung
Gespeichert in:
| Autor*in: |
Fu, Liwen [verfasserIn] |
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| Format: |
E-Artikel |
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| Sprache: |
Englisch |
| Erschienen: |
2022 |
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| Schlagwörter: |
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| Anmerkung: |
© Donghua University, Shanghai, China 2022. Springer Nature or its licensor holds exclusive rights to this article under a publishing agreement with the author(s) or other rightsholder(s); author self-archiving of the accepted manuscript version of this article is solely governed by the terms of such publishing agreement and applicable law. |
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| Übergeordnetes Werk: |
Enthalten in: Advanced fiber materials - [Berlin : Springer Nature, 2019, 4(2022), 6 vom: 05. Sept., Seite 1334-1356 |
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| Übergeordnetes Werk: |
volume:4 ; year:2022 ; number:6 ; day:05 ; month:09 ; pages:1334-1356 |
| Links: |
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| DOI / URN: |
10.1007/s42765-022-00191-2 |
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SPR048925373 |
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| 520 | |a Despite great efforts and achievement of nanomaterials in immune-associated diseases, the selection of appropriate nanomaterials and preparation technology remain some challenges and vast room for improvement. Immunotherapy has received tremendous attention throughout the medical process due to its clinical successes with the pathways of immunoactivation or immunosuppression. Recently, fibrous nanomaterials have facilitated advances in tissue repair and cancer treatments owing to the superiority of multi-channel structure, biocompatibility, tunable size and controlled surface modification. The immunoactivation-based nanofibers can potentially deliver functional agents to lesions and further actively promote immunologic intervention. On the contrary, the immunosuppression-based nanofibers prevent the immune system from overreacting through the blockage of critical pathways in vivo. This review summarizes the current application of nanofiber materials in diverse diseases, including cancer therapy, tissue regeneration (cartilage/bone, skin, tendon, nerves), myocardial infarction, psoriasis and organ defects. Some common fabrication technologies of biomedical nanofibers are also introduced. Meanwhile, the existing technical barriers and perspectives are rationally discussed, providing a constructive inspiration for the follow-up basic research and clinical transformation of nanofibers in the vibrant biomedical fields. Graphical Abstract Schematic illustration of nanofibers applied in immunoregulation-based therapy. A variety of diseases can be treated via regulating immune microenvironment including tendon regeneration, bone/cartilage repair, nerve regeneration, skin regeneration and cancer therapy. Therefore, multifunctional nanofibers can provide opportunities for future construction of efficient immune therapy for cancer immunotherapy, tissue regeneration | ||
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10.1007/s42765-022-00191-2 doi (DE-627)SPR048925373 (SPR)s42765-022-00191-2-e DE-627 ger DE-627 rakwb eng Fu, Liwen verfasserin aut Nanofibers for the Immunoregulation in Biomedical Applications 2022 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier © Donghua University, Shanghai, China 2022. Springer Nature or its licensor holds exclusive rights to this article under a publishing agreement with the author(s) or other rightsholder(s); author self-archiving of the accepted manuscript version of this article is solely governed by the terms of such publishing agreement and applicable law. Despite great efforts and achievement of nanomaterials in immune-associated diseases, the selection of appropriate nanomaterials and preparation technology remain some challenges and vast room for improvement. Immunotherapy has received tremendous attention throughout the medical process due to its clinical successes with the pathways of immunoactivation or immunosuppression. Recently, fibrous nanomaterials have facilitated advances in tissue repair and cancer treatments owing to the superiority of multi-channel structure, biocompatibility, tunable size and controlled surface modification. The immunoactivation-based nanofibers can potentially deliver functional agents to lesions and further actively promote immunologic intervention. On the contrary, the immunosuppression-based nanofibers prevent the immune system from overreacting through the blockage of critical pathways in vivo. This review summarizes the current application of nanofiber materials in diverse diseases, including cancer therapy, tissue regeneration (cartilage/bone, skin, tendon, nerves), myocardial infarction, psoriasis and organ defects. Some common fabrication technologies of biomedical nanofibers are also introduced. Meanwhile, the existing technical barriers and perspectives are rationally discussed, providing a constructive inspiration for the follow-up basic research and clinical transformation of nanofibers in the vibrant biomedical fields. Graphical Abstract Schematic illustration of nanofibers applied in immunoregulation-based therapy. A variety of diseases can be treated via regulating immune microenvironment including tendon regeneration, bone/cartilage repair, nerve regeneration, skin regeneration and cancer therapy. Therefore, multifunctional nanofibers can provide opportunities for future construction of efficient immune therapy for cancer immunotherapy, tissue regeneration Nanofibers (dpeaa)DE-He213 Immunoregulation (dpeaa)DE-He213 Tissue repair (dpeaa)DE-He213 Cancer therapy (dpeaa)DE-He213 Feng, Qian aut Chen, Yujie aut Fu, Jingzhong aut Zhou, Xiaojun aut He, Chuanglong (orcid)0000-0001-8330-8542 aut Enthalten in Advanced fiber materials [Berlin : Springer Nature, 2019 4(2022), 6 vom: 05. Sept., Seite 1334-1356 (DE-627)1688817972 (DE-600)3006816-2 2524-793X nnns volume:4 year:2022 number:6 day:05 month:09 pages:1334-1356 https://dx.doi.org/10.1007/s42765-022-00191-2 lizenzpflichtig Volltext GBV_USEFLAG_A SYSFLAG_A GBV_SPRINGER SSG-OLC-PHA GBV_ILN_11 GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_32 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_70 GBV_ILN_73 GBV_ILN_74 GBV_ILN_90 GBV_ILN_95 GBV_ILN_100 GBV_ILN_105 GBV_ILN_110 GBV_ILN_138 GBV_ILN_150 GBV_ILN_151 GBV_ILN_152 GBV_ILN_161 GBV_ILN_170 GBV_ILN_171 GBV_ILN_187 GBV_ILN_213 GBV_ILN_224 GBV_ILN_230 GBV_ILN_250 GBV_ILN_281 GBV_ILN_285 GBV_ILN_293 GBV_ILN_370 GBV_ILN_602 GBV_ILN_636 GBV_ILN_702 GBV_ILN_2001 GBV_ILN_2003 GBV_ILN_2004 GBV_ILN_2005 GBV_ILN_2006 GBV_ILN_2007 GBV_ILN_2008 GBV_ILN_2009 GBV_ILN_2010 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2015 GBV_ILN_2020 GBV_ILN_2021 GBV_ILN_2025 GBV_ILN_2026 GBV_ILN_2027 GBV_ILN_2031 GBV_ILN_2034 GBV_ILN_2037 GBV_ILN_2038 GBV_ILN_2039 GBV_ILN_2044 GBV_ILN_2048 GBV_ILN_2049 GBV_ILN_2050 GBV_ILN_2055 GBV_ILN_2056 GBV_ILN_2057 GBV_ILN_2059 GBV_ILN_2061 GBV_ILN_2064 GBV_ILN_2065 GBV_ILN_2068 GBV_ILN_2088 GBV_ILN_2093 GBV_ILN_2106 GBV_ILN_2107 GBV_ILN_2108 GBV_ILN_2110 GBV_ILN_2111 GBV_ILN_2112 GBV_ILN_2113 GBV_ILN_2118 GBV_ILN_2122 GBV_ILN_2129 GBV_ILN_2143 GBV_ILN_2144 GBV_ILN_2147 GBV_ILN_2148 GBV_ILN_2152 GBV_ILN_2153 GBV_ILN_2188 GBV_ILN_2190 GBV_ILN_2232 GBV_ILN_2336 GBV_ILN_2446 GBV_ILN_2470 GBV_ILN_2472 GBV_ILN_2507 GBV_ILN_2522 GBV_ILN_2548 GBV_ILN_4035 GBV_ILN_4037 GBV_ILN_4046 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4242 GBV_ILN_4246 GBV_ILN_4249 GBV_ILN_4251 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4326 GBV_ILN_4328 GBV_ILN_4333 GBV_ILN_4334 GBV_ILN_4335 GBV_ILN_4336 GBV_ILN_4338 GBV_ILN_4393 GBV_ILN_4700 AR 4 2022 6 05 09 1334-1356 |
| spelling |
10.1007/s42765-022-00191-2 doi (DE-627)SPR048925373 (SPR)s42765-022-00191-2-e DE-627 ger DE-627 rakwb eng Fu, Liwen verfasserin aut Nanofibers for the Immunoregulation in Biomedical Applications 2022 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier © Donghua University, Shanghai, China 2022. Springer Nature or its licensor holds exclusive rights to this article under a publishing agreement with the author(s) or other rightsholder(s); author self-archiving of the accepted manuscript version of this article is solely governed by the terms of such publishing agreement and applicable law. Despite great efforts and achievement of nanomaterials in immune-associated diseases, the selection of appropriate nanomaterials and preparation technology remain some challenges and vast room for improvement. Immunotherapy has received tremendous attention throughout the medical process due to its clinical successes with the pathways of immunoactivation or immunosuppression. Recently, fibrous nanomaterials have facilitated advances in tissue repair and cancer treatments owing to the superiority of multi-channel structure, biocompatibility, tunable size and controlled surface modification. The immunoactivation-based nanofibers can potentially deliver functional agents to lesions and further actively promote immunologic intervention. On the contrary, the immunosuppression-based nanofibers prevent the immune system from overreacting through the blockage of critical pathways in vivo. This review summarizes the current application of nanofiber materials in diverse diseases, including cancer therapy, tissue regeneration (cartilage/bone, skin, tendon, nerves), myocardial infarction, psoriasis and organ defects. Some common fabrication technologies of biomedical nanofibers are also introduced. Meanwhile, the existing technical barriers and perspectives are rationally discussed, providing a constructive inspiration for the follow-up basic research and clinical transformation of nanofibers in the vibrant biomedical fields. Graphical Abstract Schematic illustration of nanofibers applied in immunoregulation-based therapy. A variety of diseases can be treated via regulating immune microenvironment including tendon regeneration, bone/cartilage repair, nerve regeneration, skin regeneration and cancer therapy. Therefore, multifunctional nanofibers can provide opportunities for future construction of efficient immune therapy for cancer immunotherapy, tissue regeneration Nanofibers (dpeaa)DE-He213 Immunoregulation (dpeaa)DE-He213 Tissue repair (dpeaa)DE-He213 Cancer therapy (dpeaa)DE-He213 Feng, Qian aut Chen, Yujie aut Fu, Jingzhong aut Zhou, Xiaojun aut He, Chuanglong (orcid)0000-0001-8330-8542 aut Enthalten in Advanced fiber materials [Berlin : Springer Nature, 2019 4(2022), 6 vom: 05. Sept., Seite 1334-1356 (DE-627)1688817972 (DE-600)3006816-2 2524-793X nnns volume:4 year:2022 number:6 day:05 month:09 pages:1334-1356 https://dx.doi.org/10.1007/s42765-022-00191-2 lizenzpflichtig Volltext GBV_USEFLAG_A SYSFLAG_A GBV_SPRINGER SSG-OLC-PHA GBV_ILN_11 GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_32 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_70 GBV_ILN_73 GBV_ILN_74 GBV_ILN_90 GBV_ILN_95 GBV_ILN_100 GBV_ILN_105 GBV_ILN_110 GBV_ILN_138 GBV_ILN_150 GBV_ILN_151 GBV_ILN_152 GBV_ILN_161 GBV_ILN_170 GBV_ILN_171 GBV_ILN_187 GBV_ILN_213 GBV_ILN_224 GBV_ILN_230 GBV_ILN_250 GBV_ILN_281 GBV_ILN_285 GBV_ILN_293 GBV_ILN_370 GBV_ILN_602 GBV_ILN_636 GBV_ILN_702 GBV_ILN_2001 GBV_ILN_2003 GBV_ILN_2004 GBV_ILN_2005 GBV_ILN_2006 GBV_ILN_2007 GBV_ILN_2008 GBV_ILN_2009 GBV_ILN_2010 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2015 GBV_ILN_2020 GBV_ILN_2021 GBV_ILN_2025 GBV_ILN_2026 GBV_ILN_2027 GBV_ILN_2031 GBV_ILN_2034 GBV_ILN_2037 GBV_ILN_2038 GBV_ILN_2039 GBV_ILN_2044 GBV_ILN_2048 GBV_ILN_2049 GBV_ILN_2050 GBV_ILN_2055 GBV_ILN_2056 GBV_ILN_2057 GBV_ILN_2059 GBV_ILN_2061 GBV_ILN_2064 GBV_ILN_2065 GBV_ILN_2068 GBV_ILN_2088 GBV_ILN_2093 GBV_ILN_2106 GBV_ILN_2107 GBV_ILN_2108 GBV_ILN_2110 GBV_ILN_2111 GBV_ILN_2112 GBV_ILN_2113 GBV_ILN_2118 GBV_ILN_2122 GBV_ILN_2129 GBV_ILN_2143 GBV_ILN_2144 GBV_ILN_2147 GBV_ILN_2148 GBV_ILN_2152 GBV_ILN_2153 GBV_ILN_2188 GBV_ILN_2190 GBV_ILN_2232 GBV_ILN_2336 GBV_ILN_2446 GBV_ILN_2470 GBV_ILN_2472 GBV_ILN_2507 GBV_ILN_2522 GBV_ILN_2548 GBV_ILN_4035 GBV_ILN_4037 GBV_ILN_4046 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4242 GBV_ILN_4246 GBV_ILN_4249 GBV_ILN_4251 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4326 GBV_ILN_4328 GBV_ILN_4333 GBV_ILN_4334 GBV_ILN_4335 GBV_ILN_4336 GBV_ILN_4338 GBV_ILN_4393 GBV_ILN_4700 AR 4 2022 6 05 09 1334-1356 |
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10.1007/s42765-022-00191-2 doi (DE-627)SPR048925373 (SPR)s42765-022-00191-2-e DE-627 ger DE-627 rakwb eng Fu, Liwen verfasserin aut Nanofibers for the Immunoregulation in Biomedical Applications 2022 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier © Donghua University, Shanghai, China 2022. Springer Nature or its licensor holds exclusive rights to this article under a publishing agreement with the author(s) or other rightsholder(s); author self-archiving of the accepted manuscript version of this article is solely governed by the terms of such publishing agreement and applicable law. Despite great efforts and achievement of nanomaterials in immune-associated diseases, the selection of appropriate nanomaterials and preparation technology remain some challenges and vast room for improvement. Immunotherapy has received tremendous attention throughout the medical process due to its clinical successes with the pathways of immunoactivation or immunosuppression. Recently, fibrous nanomaterials have facilitated advances in tissue repair and cancer treatments owing to the superiority of multi-channel structure, biocompatibility, tunable size and controlled surface modification. The immunoactivation-based nanofibers can potentially deliver functional agents to lesions and further actively promote immunologic intervention. On the contrary, the immunosuppression-based nanofibers prevent the immune system from overreacting through the blockage of critical pathways in vivo. This review summarizes the current application of nanofiber materials in diverse diseases, including cancer therapy, tissue regeneration (cartilage/bone, skin, tendon, nerves), myocardial infarction, psoriasis and organ defects. Some common fabrication technologies of biomedical nanofibers are also introduced. Meanwhile, the existing technical barriers and perspectives are rationally discussed, providing a constructive inspiration for the follow-up basic research and clinical transformation of nanofibers in the vibrant biomedical fields. Graphical Abstract Schematic illustration of nanofibers applied in immunoregulation-based therapy. A variety of diseases can be treated via regulating immune microenvironment including tendon regeneration, bone/cartilage repair, nerve regeneration, skin regeneration and cancer therapy. Therefore, multifunctional nanofibers can provide opportunities for future construction of efficient immune therapy for cancer immunotherapy, tissue regeneration Nanofibers (dpeaa)DE-He213 Immunoregulation (dpeaa)DE-He213 Tissue repair (dpeaa)DE-He213 Cancer therapy (dpeaa)DE-He213 Feng, Qian aut Chen, Yujie aut Fu, Jingzhong aut Zhou, Xiaojun aut He, Chuanglong (orcid)0000-0001-8330-8542 aut Enthalten in Advanced fiber materials [Berlin : Springer Nature, 2019 4(2022), 6 vom: 05. Sept., Seite 1334-1356 (DE-627)1688817972 (DE-600)3006816-2 2524-793X nnns volume:4 year:2022 number:6 day:05 month:09 pages:1334-1356 https://dx.doi.org/10.1007/s42765-022-00191-2 lizenzpflichtig Volltext GBV_USEFLAG_A SYSFLAG_A GBV_SPRINGER SSG-OLC-PHA GBV_ILN_11 GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_32 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_70 GBV_ILN_73 GBV_ILN_74 GBV_ILN_90 GBV_ILN_95 GBV_ILN_100 GBV_ILN_105 GBV_ILN_110 GBV_ILN_138 GBV_ILN_150 GBV_ILN_151 GBV_ILN_152 GBV_ILN_161 GBV_ILN_170 GBV_ILN_171 GBV_ILN_187 GBV_ILN_213 GBV_ILN_224 GBV_ILN_230 GBV_ILN_250 GBV_ILN_281 GBV_ILN_285 GBV_ILN_293 GBV_ILN_370 GBV_ILN_602 GBV_ILN_636 GBV_ILN_702 GBV_ILN_2001 GBV_ILN_2003 GBV_ILN_2004 GBV_ILN_2005 GBV_ILN_2006 GBV_ILN_2007 GBV_ILN_2008 GBV_ILN_2009 GBV_ILN_2010 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2015 GBV_ILN_2020 GBV_ILN_2021 GBV_ILN_2025 GBV_ILN_2026 GBV_ILN_2027 GBV_ILN_2031 GBV_ILN_2034 GBV_ILN_2037 GBV_ILN_2038 GBV_ILN_2039 GBV_ILN_2044 GBV_ILN_2048 GBV_ILN_2049 GBV_ILN_2050 GBV_ILN_2055 GBV_ILN_2056 GBV_ILN_2057 GBV_ILN_2059 GBV_ILN_2061 GBV_ILN_2064 GBV_ILN_2065 GBV_ILN_2068 GBV_ILN_2088 GBV_ILN_2093 GBV_ILN_2106 GBV_ILN_2107 GBV_ILN_2108 GBV_ILN_2110 GBV_ILN_2111 GBV_ILN_2112 GBV_ILN_2113 GBV_ILN_2118 GBV_ILN_2122 GBV_ILN_2129 GBV_ILN_2143 GBV_ILN_2144 GBV_ILN_2147 GBV_ILN_2148 GBV_ILN_2152 GBV_ILN_2153 GBV_ILN_2188 GBV_ILN_2190 GBV_ILN_2232 GBV_ILN_2336 GBV_ILN_2446 GBV_ILN_2470 GBV_ILN_2472 GBV_ILN_2507 GBV_ILN_2522 GBV_ILN_2548 GBV_ILN_4035 GBV_ILN_4037 GBV_ILN_4046 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4242 GBV_ILN_4246 GBV_ILN_4249 GBV_ILN_4251 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4326 GBV_ILN_4328 GBV_ILN_4333 GBV_ILN_4334 GBV_ILN_4335 GBV_ILN_4336 GBV_ILN_4338 GBV_ILN_4393 GBV_ILN_4700 AR 4 2022 6 05 09 1334-1356 |
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10.1007/s42765-022-00191-2 doi (DE-627)SPR048925373 (SPR)s42765-022-00191-2-e DE-627 ger DE-627 rakwb eng Fu, Liwen verfasserin aut Nanofibers for the Immunoregulation in Biomedical Applications 2022 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier © Donghua University, Shanghai, China 2022. Springer Nature or its licensor holds exclusive rights to this article under a publishing agreement with the author(s) or other rightsholder(s); author self-archiving of the accepted manuscript version of this article is solely governed by the terms of such publishing agreement and applicable law. Despite great efforts and achievement of nanomaterials in immune-associated diseases, the selection of appropriate nanomaterials and preparation technology remain some challenges and vast room for improvement. Immunotherapy has received tremendous attention throughout the medical process due to its clinical successes with the pathways of immunoactivation or immunosuppression. Recently, fibrous nanomaterials have facilitated advances in tissue repair and cancer treatments owing to the superiority of multi-channel structure, biocompatibility, tunable size and controlled surface modification. The immunoactivation-based nanofibers can potentially deliver functional agents to lesions and further actively promote immunologic intervention. On the contrary, the immunosuppression-based nanofibers prevent the immune system from overreacting through the blockage of critical pathways in vivo. This review summarizes the current application of nanofiber materials in diverse diseases, including cancer therapy, tissue regeneration (cartilage/bone, skin, tendon, nerves), myocardial infarction, psoriasis and organ defects. Some common fabrication technologies of biomedical nanofibers are also introduced. Meanwhile, the existing technical barriers and perspectives are rationally discussed, providing a constructive inspiration for the follow-up basic research and clinical transformation of nanofibers in the vibrant biomedical fields. Graphical Abstract Schematic illustration of nanofibers applied in immunoregulation-based therapy. A variety of diseases can be treated via regulating immune microenvironment including tendon regeneration, bone/cartilage repair, nerve regeneration, skin regeneration and cancer therapy. Therefore, multifunctional nanofibers can provide opportunities for future construction of efficient immune therapy for cancer immunotherapy, tissue regeneration Nanofibers (dpeaa)DE-He213 Immunoregulation (dpeaa)DE-He213 Tissue repair (dpeaa)DE-He213 Cancer therapy (dpeaa)DE-He213 Feng, Qian aut Chen, Yujie aut Fu, Jingzhong aut Zhou, Xiaojun aut He, Chuanglong (orcid)0000-0001-8330-8542 aut Enthalten in Advanced fiber materials [Berlin : Springer Nature, 2019 4(2022), 6 vom: 05. Sept., Seite 1334-1356 (DE-627)1688817972 (DE-600)3006816-2 2524-793X nnns volume:4 year:2022 number:6 day:05 month:09 pages:1334-1356 https://dx.doi.org/10.1007/s42765-022-00191-2 lizenzpflichtig Volltext GBV_USEFLAG_A SYSFLAG_A GBV_SPRINGER SSG-OLC-PHA GBV_ILN_11 GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_32 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_70 GBV_ILN_73 GBV_ILN_74 GBV_ILN_90 GBV_ILN_95 GBV_ILN_100 GBV_ILN_105 GBV_ILN_110 GBV_ILN_138 GBV_ILN_150 GBV_ILN_151 GBV_ILN_152 GBV_ILN_161 GBV_ILN_170 GBV_ILN_171 GBV_ILN_187 GBV_ILN_213 GBV_ILN_224 GBV_ILN_230 GBV_ILN_250 GBV_ILN_281 GBV_ILN_285 GBV_ILN_293 GBV_ILN_370 GBV_ILN_602 GBV_ILN_636 GBV_ILN_702 GBV_ILN_2001 GBV_ILN_2003 GBV_ILN_2004 GBV_ILN_2005 GBV_ILN_2006 GBV_ILN_2007 GBV_ILN_2008 GBV_ILN_2009 GBV_ILN_2010 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2015 GBV_ILN_2020 GBV_ILN_2021 GBV_ILN_2025 GBV_ILN_2026 GBV_ILN_2027 GBV_ILN_2031 GBV_ILN_2034 GBV_ILN_2037 GBV_ILN_2038 GBV_ILN_2039 GBV_ILN_2044 GBV_ILN_2048 GBV_ILN_2049 GBV_ILN_2050 GBV_ILN_2055 GBV_ILN_2056 GBV_ILN_2057 GBV_ILN_2059 GBV_ILN_2061 GBV_ILN_2064 GBV_ILN_2065 GBV_ILN_2068 GBV_ILN_2088 GBV_ILN_2093 GBV_ILN_2106 GBV_ILN_2107 GBV_ILN_2108 GBV_ILN_2110 GBV_ILN_2111 GBV_ILN_2112 GBV_ILN_2113 GBV_ILN_2118 GBV_ILN_2122 GBV_ILN_2129 GBV_ILN_2143 GBV_ILN_2144 GBV_ILN_2147 GBV_ILN_2148 GBV_ILN_2152 GBV_ILN_2153 GBV_ILN_2188 GBV_ILN_2190 GBV_ILN_2232 GBV_ILN_2336 GBV_ILN_2446 GBV_ILN_2470 GBV_ILN_2472 GBV_ILN_2507 GBV_ILN_2522 GBV_ILN_2548 GBV_ILN_4035 GBV_ILN_4037 GBV_ILN_4046 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4242 GBV_ILN_4246 GBV_ILN_4249 GBV_ILN_4251 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4326 GBV_ILN_4328 GBV_ILN_4333 GBV_ILN_4334 GBV_ILN_4335 GBV_ILN_4336 GBV_ILN_4338 GBV_ILN_4393 GBV_ILN_4700 AR 4 2022 6 05 09 1334-1356 |
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10.1007/s42765-022-00191-2 doi (DE-627)SPR048925373 (SPR)s42765-022-00191-2-e DE-627 ger DE-627 rakwb eng Fu, Liwen verfasserin aut Nanofibers for the Immunoregulation in Biomedical Applications 2022 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier © Donghua University, Shanghai, China 2022. Springer Nature or its licensor holds exclusive rights to this article under a publishing agreement with the author(s) or other rightsholder(s); author self-archiving of the accepted manuscript version of this article is solely governed by the terms of such publishing agreement and applicable law. Despite great efforts and achievement of nanomaterials in immune-associated diseases, the selection of appropriate nanomaterials and preparation technology remain some challenges and vast room for improvement. Immunotherapy has received tremendous attention throughout the medical process due to its clinical successes with the pathways of immunoactivation or immunosuppression. Recently, fibrous nanomaterials have facilitated advances in tissue repair and cancer treatments owing to the superiority of multi-channel structure, biocompatibility, tunable size and controlled surface modification. The immunoactivation-based nanofibers can potentially deliver functional agents to lesions and further actively promote immunologic intervention. On the contrary, the immunosuppression-based nanofibers prevent the immune system from overreacting through the blockage of critical pathways in vivo. This review summarizes the current application of nanofiber materials in diverse diseases, including cancer therapy, tissue regeneration (cartilage/bone, skin, tendon, nerves), myocardial infarction, psoriasis and organ defects. Some common fabrication technologies of biomedical nanofibers are also introduced. Meanwhile, the existing technical barriers and perspectives are rationally discussed, providing a constructive inspiration for the follow-up basic research and clinical transformation of nanofibers in the vibrant biomedical fields. Graphical Abstract Schematic illustration of nanofibers applied in immunoregulation-based therapy. A variety of diseases can be treated via regulating immune microenvironment including tendon regeneration, bone/cartilage repair, nerve regeneration, skin regeneration and cancer therapy. Therefore, multifunctional nanofibers can provide opportunities for future construction of efficient immune therapy for cancer immunotherapy, tissue regeneration Nanofibers (dpeaa)DE-He213 Immunoregulation (dpeaa)DE-He213 Tissue repair (dpeaa)DE-He213 Cancer therapy (dpeaa)DE-He213 Feng, Qian aut Chen, Yujie aut Fu, Jingzhong aut Zhou, Xiaojun aut He, Chuanglong (orcid)0000-0001-8330-8542 aut Enthalten in Advanced fiber materials [Berlin : Springer Nature, 2019 4(2022), 6 vom: 05. Sept., Seite 1334-1356 (DE-627)1688817972 (DE-600)3006816-2 2524-793X nnns volume:4 year:2022 number:6 day:05 month:09 pages:1334-1356 https://dx.doi.org/10.1007/s42765-022-00191-2 lizenzpflichtig Volltext GBV_USEFLAG_A SYSFLAG_A GBV_SPRINGER SSG-OLC-PHA GBV_ILN_11 GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_32 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_70 GBV_ILN_73 GBV_ILN_74 GBV_ILN_90 GBV_ILN_95 GBV_ILN_100 GBV_ILN_105 GBV_ILN_110 GBV_ILN_138 GBV_ILN_150 GBV_ILN_151 GBV_ILN_152 GBV_ILN_161 GBV_ILN_170 GBV_ILN_171 GBV_ILN_187 GBV_ILN_213 GBV_ILN_224 GBV_ILN_230 GBV_ILN_250 GBV_ILN_281 GBV_ILN_285 GBV_ILN_293 GBV_ILN_370 GBV_ILN_602 GBV_ILN_636 GBV_ILN_702 GBV_ILN_2001 GBV_ILN_2003 GBV_ILN_2004 GBV_ILN_2005 GBV_ILN_2006 GBV_ILN_2007 GBV_ILN_2008 GBV_ILN_2009 GBV_ILN_2010 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2015 GBV_ILN_2020 GBV_ILN_2021 GBV_ILN_2025 GBV_ILN_2026 GBV_ILN_2027 GBV_ILN_2031 GBV_ILN_2034 GBV_ILN_2037 GBV_ILN_2038 GBV_ILN_2039 GBV_ILN_2044 GBV_ILN_2048 GBV_ILN_2049 GBV_ILN_2050 GBV_ILN_2055 GBV_ILN_2056 GBV_ILN_2057 GBV_ILN_2059 GBV_ILN_2061 GBV_ILN_2064 GBV_ILN_2065 GBV_ILN_2068 GBV_ILN_2088 GBV_ILN_2093 GBV_ILN_2106 GBV_ILN_2107 GBV_ILN_2108 GBV_ILN_2110 GBV_ILN_2111 GBV_ILN_2112 GBV_ILN_2113 GBV_ILN_2118 GBV_ILN_2122 GBV_ILN_2129 GBV_ILN_2143 GBV_ILN_2144 GBV_ILN_2147 GBV_ILN_2148 GBV_ILN_2152 GBV_ILN_2153 GBV_ILN_2188 GBV_ILN_2190 GBV_ILN_2232 GBV_ILN_2336 GBV_ILN_2446 GBV_ILN_2470 GBV_ILN_2472 GBV_ILN_2507 GBV_ILN_2522 GBV_ILN_2548 GBV_ILN_4035 GBV_ILN_4037 GBV_ILN_4046 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4242 GBV_ILN_4246 GBV_ILN_4249 GBV_ILN_4251 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4326 GBV_ILN_4328 GBV_ILN_4333 GBV_ILN_4334 GBV_ILN_4335 GBV_ILN_4336 GBV_ILN_4338 GBV_ILN_4393 GBV_ILN_4700 AR 4 2022 6 05 09 1334-1356 |
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nanofibers for the immunoregulation in biomedical applications |
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Nanofibers for the Immunoregulation in Biomedical Applications |
| abstract |
Despite great efforts and achievement of nanomaterials in immune-associated diseases, the selection of appropriate nanomaterials and preparation technology remain some challenges and vast room for improvement. Immunotherapy has received tremendous attention throughout the medical process due to its clinical successes with the pathways of immunoactivation or immunosuppression. Recently, fibrous nanomaterials have facilitated advances in tissue repair and cancer treatments owing to the superiority of multi-channel structure, biocompatibility, tunable size and controlled surface modification. The immunoactivation-based nanofibers can potentially deliver functional agents to lesions and further actively promote immunologic intervention. On the contrary, the immunosuppression-based nanofibers prevent the immune system from overreacting through the blockage of critical pathways in vivo. This review summarizes the current application of nanofiber materials in diverse diseases, including cancer therapy, tissue regeneration (cartilage/bone, skin, tendon, nerves), myocardial infarction, psoriasis and organ defects. Some common fabrication technologies of biomedical nanofibers are also introduced. Meanwhile, the existing technical barriers and perspectives are rationally discussed, providing a constructive inspiration for the follow-up basic research and clinical transformation of nanofibers in the vibrant biomedical fields. Graphical Abstract Schematic illustration of nanofibers applied in immunoregulation-based therapy. A variety of diseases can be treated via regulating immune microenvironment including tendon regeneration, bone/cartilage repair, nerve regeneration, skin regeneration and cancer therapy. Therefore, multifunctional nanofibers can provide opportunities for future construction of efficient immune therapy for cancer immunotherapy, tissue regeneration © Donghua University, Shanghai, China 2022. Springer Nature or its licensor holds exclusive rights to this article under a publishing agreement with the author(s) or other rightsholder(s); author self-archiving of the accepted manuscript version of this article is solely governed by the terms of such publishing agreement and applicable law. |
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Despite great efforts and achievement of nanomaterials in immune-associated diseases, the selection of appropriate nanomaterials and preparation technology remain some challenges and vast room for improvement. Immunotherapy has received tremendous attention throughout the medical process due to its clinical successes with the pathways of immunoactivation or immunosuppression. Recently, fibrous nanomaterials have facilitated advances in tissue repair and cancer treatments owing to the superiority of multi-channel structure, biocompatibility, tunable size and controlled surface modification. The immunoactivation-based nanofibers can potentially deliver functional agents to lesions and further actively promote immunologic intervention. On the contrary, the immunosuppression-based nanofibers prevent the immune system from overreacting through the blockage of critical pathways in vivo. This review summarizes the current application of nanofiber materials in diverse diseases, including cancer therapy, tissue regeneration (cartilage/bone, skin, tendon, nerves), myocardial infarction, psoriasis and organ defects. Some common fabrication technologies of biomedical nanofibers are also introduced. Meanwhile, the existing technical barriers and perspectives are rationally discussed, providing a constructive inspiration for the follow-up basic research and clinical transformation of nanofibers in the vibrant biomedical fields. Graphical Abstract Schematic illustration of nanofibers applied in immunoregulation-based therapy. A variety of diseases can be treated via regulating immune microenvironment including tendon regeneration, bone/cartilage repair, nerve regeneration, skin regeneration and cancer therapy. Therefore, multifunctional nanofibers can provide opportunities for future construction of efficient immune therapy for cancer immunotherapy, tissue regeneration © Donghua University, Shanghai, China 2022. Springer Nature or its licensor holds exclusive rights to this article under a publishing agreement with the author(s) or other rightsholder(s); author self-archiving of the accepted manuscript version of this article is solely governed by the terms of such publishing agreement and applicable law. |
| abstract_unstemmed |
Despite great efforts and achievement of nanomaterials in immune-associated diseases, the selection of appropriate nanomaterials and preparation technology remain some challenges and vast room for improvement. Immunotherapy has received tremendous attention throughout the medical process due to its clinical successes with the pathways of immunoactivation or immunosuppression. Recently, fibrous nanomaterials have facilitated advances in tissue repair and cancer treatments owing to the superiority of multi-channel structure, biocompatibility, tunable size and controlled surface modification. The immunoactivation-based nanofibers can potentially deliver functional agents to lesions and further actively promote immunologic intervention. On the contrary, the immunosuppression-based nanofibers prevent the immune system from overreacting through the blockage of critical pathways in vivo. This review summarizes the current application of nanofiber materials in diverse diseases, including cancer therapy, tissue regeneration (cartilage/bone, skin, tendon, nerves), myocardial infarction, psoriasis and organ defects. Some common fabrication technologies of biomedical nanofibers are also introduced. Meanwhile, the existing technical barriers and perspectives are rationally discussed, providing a constructive inspiration for the follow-up basic research and clinical transformation of nanofibers in the vibrant biomedical fields. Graphical Abstract Schematic illustration of nanofibers applied in immunoregulation-based therapy. A variety of diseases can be treated via regulating immune microenvironment including tendon regeneration, bone/cartilage repair, nerve regeneration, skin regeneration and cancer therapy. Therefore, multifunctional nanofibers can provide opportunities for future construction of efficient immune therapy for cancer immunotherapy, tissue regeneration © Donghua University, Shanghai, China 2022. Springer Nature or its licensor holds exclusive rights to this article under a publishing agreement with the author(s) or other rightsholder(s); author self-archiving of the accepted manuscript version of this article is solely governed by the terms of such publishing agreement and applicable law. |
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Nanofibers for the Immunoregulation in Biomedical Applications |
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Feng, Qian Chen, Yujie Fu, Jingzhong Zhou, Xiaojun He, Chuanglong |
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2024-07-03T22:17:35.103Z |
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| score |
7.3984203 |