Evaluation of oncological outcomes of robotic partial nephrectomy according to the type of hilar control approach (On-clamp vs Off-clamp), a multicentric study of the French network of research on kidney cancer—UROCCR 58-NCT03293563
Purpose To compare off-clamp vs on-clamp robotic partial nephrectomy (RPN) for renal cell carcinoma (RCC) in terms of oncological outcomes, and to assess the impact of surgical experience (SE). Methods We extracted data of a contemporary cohort of 1359 patients from the prospectively maintained data...
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| Autor*in: |
Mellouki, Adil [verfasserIn] |
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E-Artikel |
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| Sprache: |
Englisch |
| Erschienen: |
2021 |
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| Anmerkung: |
© The Author(s), under exclusive licence to Springer-Verlag GmbH, DE part of Springer Nature 2021 |
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| Übergeordnetes Werk: |
Enthalten in: World journal of urology - Berlin : Springer, 1983, 41(2021), 2 vom: 19. Feb., Seite 287-294 |
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| Übergeordnetes Werk: |
volume:41 ; year:2021 ; number:2 ; day:19 ; month:02 ; pages:287-294 |
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| DOI / URN: |
10.1007/s00345-020-03558-5 |
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| Katalog-ID: |
SPR049430823 |
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| 100 | 1 | |a Mellouki, Adil |e verfasserin |4 aut | |
| 245 | 1 | 0 | |a Evaluation of oncological outcomes of robotic partial nephrectomy according to the type of hilar control approach (On-clamp vs Off-clamp), a multicentric study of the French network of research on kidney cancer—UROCCR 58-NCT03293563 |
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| 500 | |a © The Author(s), under exclusive licence to Springer-Verlag GmbH, DE part of Springer Nature 2021 | ||
| 520 | |a Purpose To compare off-clamp vs on-clamp robotic partial nephrectomy (RPN) for renal cell carcinoma (RCC) in terms of oncological outcomes, and to assess the impact of surgical experience (SE). Methods We extracted data of a contemporary cohort of 1359 patients from the prospectively maintained database of the French national network of research on kidney cancer (UROCCR). The primary objective was to assess the positive surgical margin (PSM) rate. We also evaluated the oncological outcomes regardless of the surgical experience (SE) by dividing patients into three groups of SE as a secondary endpoints. SE was defined by the caseload of RPN per surgeon per year. For the continuous variables, we used Mann–Whitney and Student tests. We assessed survival analysis according to hilar control approach by Kaplan–Meier curves with log rank tests. A logistic regression multivariate analysis was used to evaluate the independent factors of PSM. Results Outcomes of 224 off-clamp RPN for RCC were compared to 1135 on-clamp RPN. PSM rate was not statistically different, with 5.6% in the off-clamp group, and 11% in the on-clamp group (p = 0.1). When assessing survival analysis for overall survival (OS), local recurrence-free survival (LR), and metastasis-free survival (MFS) according to hilar clamping approach, there were no statistically significant differences between the two groups with p value log rank = 0.2, 0.8, 0.1, respectively. In multivariate analysis assessing SE, hilar control approach, hospital volume (HV), RENAL score, gender, Age, ECOG, EBL, BMI, and indication of NSS, age at surgery was associated with PSM (odds ratio [OR] 1.03 (95% CI 1.00–1.04), 0.02), whereas SE, HV, and type of hilar control approach were not predictive factors of PSM. Conclusion Hilar control approach seems to have no impact on PSM of RPN for RCC. Our findings were consistent with randomized trials. | ||
| 650 | 4 | |a Hilar control approach |7 (dpeaa)DE-He213 | |
| 650 | 4 | |a Kidney cancer |7 (dpeaa)DE-He213 | |
| 650 | 4 | |a Oncological outcomes |7 (dpeaa)DE-He213 | |
| 650 | 4 | |a Positive surgical margins |7 (dpeaa)DE-He213 | |
| 650 | 4 | |a Robotic partial nephrectomy |7 (dpeaa)DE-He213 | |
| 700 | 1 | |a Bentellis, Imad |4 aut | |
| 700 | 1 | |a Morrone, Arnoult |4 aut | |
| 700 | 1 | |a Doumerc, Nicolas |4 aut | |
| 700 | 1 | |a Beauval, Jean-Baptiste |4 aut | |
| 700 | 1 | |a Roupret, Morgane |4 aut | |
| 700 | 1 | |a Nouhaud, François-Xavier |4 aut | |
| 700 | 1 | |a Lebacle, Cedric |4 aut | |
| 700 | 1 | |a Long, Jean-Alexandre |4 aut | |
| 700 | 1 | |a Chevallier, Daniel |4 aut | |
| 700 | 1 | |a Tibi, Brannwel |4 aut | |
| 700 | 1 | |a Shaikh, Aysha |4 aut | |
| 700 | 1 | |a Imbert de la Phalecque, L. |4 aut | |
| 700 | 1 | |a Pillot, Pierre |4 aut | |
| 700 | 1 | |a Tillou, Xavier |4 aut | |
| 700 | 1 | |a Bernhard, Jean-Christophe |4 aut | |
| 700 | 1 | |a Durand, Matthieu |4 aut | |
| 700 | 1 | |a Ahallal, Youness |4 aut | |
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10.1007/s00345-020-03558-5 doi (DE-627)SPR049430823 (SPR)s00345-020-03558-5-e DE-627 ger DE-627 rakwb eng Mellouki, Adil verfasserin aut Evaluation of oncological outcomes of robotic partial nephrectomy according to the type of hilar control approach (On-clamp vs Off-clamp), a multicentric study of the French network of research on kidney cancer—UROCCR 58-NCT03293563 2021 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier © The Author(s), under exclusive licence to Springer-Verlag GmbH, DE part of Springer Nature 2021 Purpose To compare off-clamp vs on-clamp robotic partial nephrectomy (RPN) for renal cell carcinoma (RCC) in terms of oncological outcomes, and to assess the impact of surgical experience (SE). Methods We extracted data of a contemporary cohort of 1359 patients from the prospectively maintained database of the French national network of research on kidney cancer (UROCCR). The primary objective was to assess the positive surgical margin (PSM) rate. We also evaluated the oncological outcomes regardless of the surgical experience (SE) by dividing patients into three groups of SE as a secondary endpoints. SE was defined by the caseload of RPN per surgeon per year. For the continuous variables, we used Mann–Whitney and Student tests. We assessed survival analysis according to hilar control approach by Kaplan–Meier curves with log rank tests. A logistic regression multivariate analysis was used to evaluate the independent factors of PSM. Results Outcomes of 224 off-clamp RPN for RCC were compared to 1135 on-clamp RPN. PSM rate was not statistically different, with 5.6% in the off-clamp group, and 11% in the on-clamp group (p = 0.1). When assessing survival analysis for overall survival (OS), local recurrence-free survival (LR), and metastasis-free survival (MFS) according to hilar clamping approach, there were no statistically significant differences between the two groups with p value log rank = 0.2, 0.8, 0.1, respectively. In multivariate analysis assessing SE, hilar control approach, hospital volume (HV), RENAL score, gender, Age, ECOG, EBL, BMI, and indication of NSS, age at surgery was associated with PSM (odds ratio [OR] 1.03 (95% CI 1.00–1.04), 0.02), whereas SE, HV, and type of hilar control approach were not predictive factors of PSM. Conclusion Hilar control approach seems to have no impact on PSM of RPN for RCC. Our findings were consistent with randomized trials. Hilar control approach (dpeaa)DE-He213 Kidney cancer (dpeaa)DE-He213 Oncological outcomes (dpeaa)DE-He213 Positive surgical margins (dpeaa)DE-He213 Robotic partial nephrectomy (dpeaa)DE-He213 Bentellis, Imad aut Morrone, Arnoult aut Doumerc, Nicolas aut Beauval, Jean-Baptiste aut Roupret, Morgane aut Nouhaud, François-Xavier aut Lebacle, Cedric aut Long, Jean-Alexandre aut Chevallier, Daniel aut Tibi, Brannwel aut Shaikh, Aysha aut Imbert de la Phalecque, L. aut Pillot, Pierre aut Tillou, Xavier aut Bernhard, Jean-Christophe aut Durand, Matthieu aut Ahallal, Youness aut Enthalten in World journal of urology Berlin : Springer, 1983 41(2021), 2 vom: 19. Feb., Seite 287-294 (DE-627)254910874 (DE-600)1463303-6 1433-8726 nnns volume:41 year:2021 number:2 day:19 month:02 pages:287-294 https://dx.doi.org/10.1007/s00345-020-03558-5 lizenzpflichtig Volltext GBV_USEFLAG_A SYSFLAG_A GBV_SPRINGER GBV_ILN_11 GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_32 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_69 GBV_ILN_70 GBV_ILN_73 GBV_ILN_74 GBV_ILN_90 GBV_ILN_95 GBV_ILN_100 GBV_ILN_101 GBV_ILN_105 GBV_ILN_110 GBV_ILN_120 GBV_ILN_138 GBV_ILN_150 GBV_ILN_151 GBV_ILN_152 GBV_ILN_161 GBV_ILN_170 GBV_ILN_171 GBV_ILN_187 GBV_ILN_213 GBV_ILN_224 GBV_ILN_230 GBV_ILN_250 GBV_ILN_267 GBV_ILN_281 GBV_ILN_285 GBV_ILN_293 GBV_ILN_370 GBV_ILN_602 GBV_ILN_636 GBV_ILN_702 GBV_ILN_711 GBV_ILN_2001 GBV_ILN_2003 GBV_ILN_2004 GBV_ILN_2005 GBV_ILN_2006 GBV_ILN_2007 GBV_ILN_2008 GBV_ILN_2009 GBV_ILN_2010 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2015 GBV_ILN_2020 GBV_ILN_2021 GBV_ILN_2025 GBV_ILN_2026 GBV_ILN_2027 GBV_ILN_2031 GBV_ILN_2034 GBV_ILN_2037 GBV_ILN_2038 GBV_ILN_2039 GBV_ILN_2044 GBV_ILN_2048 GBV_ILN_2049 GBV_ILN_2050 GBV_ILN_2055 GBV_ILN_2056 GBV_ILN_2057 GBV_ILN_2059 GBV_ILN_2061 GBV_ILN_2064 GBV_ILN_2065 GBV_ILN_2068 GBV_ILN_2088 GBV_ILN_2093 GBV_ILN_2106 GBV_ILN_2107 GBV_ILN_2108 GBV_ILN_2110 GBV_ILN_2111 GBV_ILN_2112 GBV_ILN_2113 GBV_ILN_2118 GBV_ILN_2122 GBV_ILN_2129 GBV_ILN_2143 GBV_ILN_2144 GBV_ILN_2147 GBV_ILN_2148 GBV_ILN_2152 GBV_ILN_2153 GBV_ILN_2188 GBV_ILN_2190 GBV_ILN_2232 GBV_ILN_2336 GBV_ILN_2446 GBV_ILN_2470 GBV_ILN_2472 GBV_ILN_2507 GBV_ILN_2522 GBV_ILN_2548 GBV_ILN_4035 GBV_ILN_4037 GBV_ILN_4046 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4242 GBV_ILN_4246 GBV_ILN_4249 GBV_ILN_4251 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4326 GBV_ILN_4328 GBV_ILN_4333 GBV_ILN_4334 GBV_ILN_4335 GBV_ILN_4336 GBV_ILN_4338 GBV_ILN_4393 GBV_ILN_4700 AR 41 2021 2 19 02 287-294 |
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10.1007/s00345-020-03558-5 doi (DE-627)SPR049430823 (SPR)s00345-020-03558-5-e DE-627 ger DE-627 rakwb eng Mellouki, Adil verfasserin aut Evaluation of oncological outcomes of robotic partial nephrectomy according to the type of hilar control approach (On-clamp vs Off-clamp), a multicentric study of the French network of research on kidney cancer—UROCCR 58-NCT03293563 2021 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier © The Author(s), under exclusive licence to Springer-Verlag GmbH, DE part of Springer Nature 2021 Purpose To compare off-clamp vs on-clamp robotic partial nephrectomy (RPN) for renal cell carcinoma (RCC) in terms of oncological outcomes, and to assess the impact of surgical experience (SE). Methods We extracted data of a contemporary cohort of 1359 patients from the prospectively maintained database of the French national network of research on kidney cancer (UROCCR). The primary objective was to assess the positive surgical margin (PSM) rate. We also evaluated the oncological outcomes regardless of the surgical experience (SE) by dividing patients into three groups of SE as a secondary endpoints. SE was defined by the caseload of RPN per surgeon per year. For the continuous variables, we used Mann–Whitney and Student tests. We assessed survival analysis according to hilar control approach by Kaplan–Meier curves with log rank tests. A logistic regression multivariate analysis was used to evaluate the independent factors of PSM. Results Outcomes of 224 off-clamp RPN for RCC were compared to 1135 on-clamp RPN. PSM rate was not statistically different, with 5.6% in the off-clamp group, and 11% in the on-clamp group (p = 0.1). When assessing survival analysis for overall survival (OS), local recurrence-free survival (LR), and metastasis-free survival (MFS) according to hilar clamping approach, there were no statistically significant differences between the two groups with p value log rank = 0.2, 0.8, 0.1, respectively. In multivariate analysis assessing SE, hilar control approach, hospital volume (HV), RENAL score, gender, Age, ECOG, EBL, BMI, and indication of NSS, age at surgery was associated with PSM (odds ratio [OR] 1.03 (95% CI 1.00–1.04), 0.02), whereas SE, HV, and type of hilar control approach were not predictive factors of PSM. Conclusion Hilar control approach seems to have no impact on PSM of RPN for RCC. Our findings were consistent with randomized trials. Hilar control approach (dpeaa)DE-He213 Kidney cancer (dpeaa)DE-He213 Oncological outcomes (dpeaa)DE-He213 Positive surgical margins (dpeaa)DE-He213 Robotic partial nephrectomy (dpeaa)DE-He213 Bentellis, Imad aut Morrone, Arnoult aut Doumerc, Nicolas aut Beauval, Jean-Baptiste aut Roupret, Morgane aut Nouhaud, François-Xavier aut Lebacle, Cedric aut Long, Jean-Alexandre aut Chevallier, Daniel aut Tibi, Brannwel aut Shaikh, Aysha aut Imbert de la Phalecque, L. aut Pillot, Pierre aut Tillou, Xavier aut Bernhard, Jean-Christophe aut Durand, Matthieu aut Ahallal, Youness aut Enthalten in World journal of urology Berlin : Springer, 1983 41(2021), 2 vom: 19. Feb., Seite 287-294 (DE-627)254910874 (DE-600)1463303-6 1433-8726 nnns volume:41 year:2021 number:2 day:19 month:02 pages:287-294 https://dx.doi.org/10.1007/s00345-020-03558-5 lizenzpflichtig Volltext GBV_USEFLAG_A SYSFLAG_A GBV_SPRINGER GBV_ILN_11 GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_32 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_69 GBV_ILN_70 GBV_ILN_73 GBV_ILN_74 GBV_ILN_90 GBV_ILN_95 GBV_ILN_100 GBV_ILN_101 GBV_ILN_105 GBV_ILN_110 GBV_ILN_120 GBV_ILN_138 GBV_ILN_150 GBV_ILN_151 GBV_ILN_152 GBV_ILN_161 GBV_ILN_170 GBV_ILN_171 GBV_ILN_187 GBV_ILN_213 GBV_ILN_224 GBV_ILN_230 GBV_ILN_250 GBV_ILN_267 GBV_ILN_281 GBV_ILN_285 GBV_ILN_293 GBV_ILN_370 GBV_ILN_602 GBV_ILN_636 GBV_ILN_702 GBV_ILN_711 GBV_ILN_2001 GBV_ILN_2003 GBV_ILN_2004 GBV_ILN_2005 GBV_ILN_2006 GBV_ILN_2007 GBV_ILN_2008 GBV_ILN_2009 GBV_ILN_2010 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2015 GBV_ILN_2020 GBV_ILN_2021 GBV_ILN_2025 GBV_ILN_2026 GBV_ILN_2027 GBV_ILN_2031 GBV_ILN_2034 GBV_ILN_2037 GBV_ILN_2038 GBV_ILN_2039 GBV_ILN_2044 GBV_ILN_2048 GBV_ILN_2049 GBV_ILN_2050 GBV_ILN_2055 GBV_ILN_2056 GBV_ILN_2057 GBV_ILN_2059 GBV_ILN_2061 GBV_ILN_2064 GBV_ILN_2065 GBV_ILN_2068 GBV_ILN_2088 GBV_ILN_2093 GBV_ILN_2106 GBV_ILN_2107 GBV_ILN_2108 GBV_ILN_2110 GBV_ILN_2111 GBV_ILN_2112 GBV_ILN_2113 GBV_ILN_2118 GBV_ILN_2122 GBV_ILN_2129 GBV_ILN_2143 GBV_ILN_2144 GBV_ILN_2147 GBV_ILN_2148 GBV_ILN_2152 GBV_ILN_2153 GBV_ILN_2188 GBV_ILN_2190 GBV_ILN_2232 GBV_ILN_2336 GBV_ILN_2446 GBV_ILN_2470 GBV_ILN_2472 GBV_ILN_2507 GBV_ILN_2522 GBV_ILN_2548 GBV_ILN_4035 GBV_ILN_4037 GBV_ILN_4046 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4242 GBV_ILN_4246 GBV_ILN_4249 GBV_ILN_4251 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4326 GBV_ILN_4328 GBV_ILN_4333 GBV_ILN_4334 GBV_ILN_4335 GBV_ILN_4336 GBV_ILN_4338 GBV_ILN_4393 GBV_ILN_4700 AR 41 2021 2 19 02 287-294 |
| allfields_unstemmed |
10.1007/s00345-020-03558-5 doi (DE-627)SPR049430823 (SPR)s00345-020-03558-5-e DE-627 ger DE-627 rakwb eng Mellouki, Adil verfasserin aut Evaluation of oncological outcomes of robotic partial nephrectomy according to the type of hilar control approach (On-clamp vs Off-clamp), a multicentric study of the French network of research on kidney cancer—UROCCR 58-NCT03293563 2021 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier © The Author(s), under exclusive licence to Springer-Verlag GmbH, DE part of Springer Nature 2021 Purpose To compare off-clamp vs on-clamp robotic partial nephrectomy (RPN) for renal cell carcinoma (RCC) in terms of oncological outcomes, and to assess the impact of surgical experience (SE). Methods We extracted data of a contemporary cohort of 1359 patients from the prospectively maintained database of the French national network of research on kidney cancer (UROCCR). The primary objective was to assess the positive surgical margin (PSM) rate. We also evaluated the oncological outcomes regardless of the surgical experience (SE) by dividing patients into three groups of SE as a secondary endpoints. SE was defined by the caseload of RPN per surgeon per year. For the continuous variables, we used Mann–Whitney and Student tests. We assessed survival analysis according to hilar control approach by Kaplan–Meier curves with log rank tests. A logistic regression multivariate analysis was used to evaluate the independent factors of PSM. Results Outcomes of 224 off-clamp RPN for RCC were compared to 1135 on-clamp RPN. PSM rate was not statistically different, with 5.6% in the off-clamp group, and 11% in the on-clamp group (p = 0.1). When assessing survival analysis for overall survival (OS), local recurrence-free survival (LR), and metastasis-free survival (MFS) according to hilar clamping approach, there were no statistically significant differences between the two groups with p value log rank = 0.2, 0.8, 0.1, respectively. In multivariate analysis assessing SE, hilar control approach, hospital volume (HV), RENAL score, gender, Age, ECOG, EBL, BMI, and indication of NSS, age at surgery was associated with PSM (odds ratio [OR] 1.03 (95% CI 1.00–1.04), 0.02), whereas SE, HV, and type of hilar control approach were not predictive factors of PSM. Conclusion Hilar control approach seems to have no impact on PSM of RPN for RCC. Our findings were consistent with randomized trials. Hilar control approach (dpeaa)DE-He213 Kidney cancer (dpeaa)DE-He213 Oncological outcomes (dpeaa)DE-He213 Positive surgical margins (dpeaa)DE-He213 Robotic partial nephrectomy (dpeaa)DE-He213 Bentellis, Imad aut Morrone, Arnoult aut Doumerc, Nicolas aut Beauval, Jean-Baptiste aut Roupret, Morgane aut Nouhaud, François-Xavier aut Lebacle, Cedric aut Long, Jean-Alexandre aut Chevallier, Daniel aut Tibi, Brannwel aut Shaikh, Aysha aut Imbert de la Phalecque, L. aut Pillot, Pierre aut Tillou, Xavier aut Bernhard, Jean-Christophe aut Durand, Matthieu aut Ahallal, Youness aut Enthalten in World journal of urology Berlin : Springer, 1983 41(2021), 2 vom: 19. Feb., Seite 287-294 (DE-627)254910874 (DE-600)1463303-6 1433-8726 nnns volume:41 year:2021 number:2 day:19 month:02 pages:287-294 https://dx.doi.org/10.1007/s00345-020-03558-5 lizenzpflichtig Volltext GBV_USEFLAG_A SYSFLAG_A GBV_SPRINGER GBV_ILN_11 GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_32 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_69 GBV_ILN_70 GBV_ILN_73 GBV_ILN_74 GBV_ILN_90 GBV_ILN_95 GBV_ILN_100 GBV_ILN_101 GBV_ILN_105 GBV_ILN_110 GBV_ILN_120 GBV_ILN_138 GBV_ILN_150 GBV_ILN_151 GBV_ILN_152 GBV_ILN_161 GBV_ILN_170 GBV_ILN_171 GBV_ILN_187 GBV_ILN_213 GBV_ILN_224 GBV_ILN_230 GBV_ILN_250 GBV_ILN_267 GBV_ILN_281 GBV_ILN_285 GBV_ILN_293 GBV_ILN_370 GBV_ILN_602 GBV_ILN_636 GBV_ILN_702 GBV_ILN_711 GBV_ILN_2001 GBV_ILN_2003 GBV_ILN_2004 GBV_ILN_2005 GBV_ILN_2006 GBV_ILN_2007 GBV_ILN_2008 GBV_ILN_2009 GBV_ILN_2010 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2015 GBV_ILN_2020 GBV_ILN_2021 GBV_ILN_2025 GBV_ILN_2026 GBV_ILN_2027 GBV_ILN_2031 GBV_ILN_2034 GBV_ILN_2037 GBV_ILN_2038 GBV_ILN_2039 GBV_ILN_2044 GBV_ILN_2048 GBV_ILN_2049 GBV_ILN_2050 GBV_ILN_2055 GBV_ILN_2056 GBV_ILN_2057 GBV_ILN_2059 GBV_ILN_2061 GBV_ILN_2064 GBV_ILN_2065 GBV_ILN_2068 GBV_ILN_2088 GBV_ILN_2093 GBV_ILN_2106 GBV_ILN_2107 GBV_ILN_2108 GBV_ILN_2110 GBV_ILN_2111 GBV_ILN_2112 GBV_ILN_2113 GBV_ILN_2118 GBV_ILN_2122 GBV_ILN_2129 GBV_ILN_2143 GBV_ILN_2144 GBV_ILN_2147 GBV_ILN_2148 GBV_ILN_2152 GBV_ILN_2153 GBV_ILN_2188 GBV_ILN_2190 GBV_ILN_2232 GBV_ILN_2336 GBV_ILN_2446 GBV_ILN_2470 GBV_ILN_2472 GBV_ILN_2507 GBV_ILN_2522 GBV_ILN_2548 GBV_ILN_4035 GBV_ILN_4037 GBV_ILN_4046 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4242 GBV_ILN_4246 GBV_ILN_4249 GBV_ILN_4251 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4326 GBV_ILN_4328 GBV_ILN_4333 GBV_ILN_4334 GBV_ILN_4335 GBV_ILN_4336 GBV_ILN_4338 GBV_ILN_4393 GBV_ILN_4700 AR 41 2021 2 19 02 287-294 |
| allfieldsGer |
10.1007/s00345-020-03558-5 doi (DE-627)SPR049430823 (SPR)s00345-020-03558-5-e DE-627 ger DE-627 rakwb eng Mellouki, Adil verfasserin aut Evaluation of oncological outcomes of robotic partial nephrectomy according to the type of hilar control approach (On-clamp vs Off-clamp), a multicentric study of the French network of research on kidney cancer—UROCCR 58-NCT03293563 2021 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier © The Author(s), under exclusive licence to Springer-Verlag GmbH, DE part of Springer Nature 2021 Purpose To compare off-clamp vs on-clamp robotic partial nephrectomy (RPN) for renal cell carcinoma (RCC) in terms of oncological outcomes, and to assess the impact of surgical experience (SE). Methods We extracted data of a contemporary cohort of 1359 patients from the prospectively maintained database of the French national network of research on kidney cancer (UROCCR). The primary objective was to assess the positive surgical margin (PSM) rate. We also evaluated the oncological outcomes regardless of the surgical experience (SE) by dividing patients into three groups of SE as a secondary endpoints. SE was defined by the caseload of RPN per surgeon per year. For the continuous variables, we used Mann–Whitney and Student tests. We assessed survival analysis according to hilar control approach by Kaplan–Meier curves with log rank tests. A logistic regression multivariate analysis was used to evaluate the independent factors of PSM. Results Outcomes of 224 off-clamp RPN for RCC were compared to 1135 on-clamp RPN. PSM rate was not statistically different, with 5.6% in the off-clamp group, and 11% in the on-clamp group (p = 0.1). When assessing survival analysis for overall survival (OS), local recurrence-free survival (LR), and metastasis-free survival (MFS) according to hilar clamping approach, there were no statistically significant differences between the two groups with p value log rank = 0.2, 0.8, 0.1, respectively. In multivariate analysis assessing SE, hilar control approach, hospital volume (HV), RENAL score, gender, Age, ECOG, EBL, BMI, and indication of NSS, age at surgery was associated with PSM (odds ratio [OR] 1.03 (95% CI 1.00–1.04), 0.02), whereas SE, HV, and type of hilar control approach were not predictive factors of PSM. Conclusion Hilar control approach seems to have no impact on PSM of RPN for RCC. Our findings were consistent with randomized trials. Hilar control approach (dpeaa)DE-He213 Kidney cancer (dpeaa)DE-He213 Oncological outcomes (dpeaa)DE-He213 Positive surgical margins (dpeaa)DE-He213 Robotic partial nephrectomy (dpeaa)DE-He213 Bentellis, Imad aut Morrone, Arnoult aut Doumerc, Nicolas aut Beauval, Jean-Baptiste aut Roupret, Morgane aut Nouhaud, François-Xavier aut Lebacle, Cedric aut Long, Jean-Alexandre aut Chevallier, Daniel aut Tibi, Brannwel aut Shaikh, Aysha aut Imbert de la Phalecque, L. aut Pillot, Pierre aut Tillou, Xavier aut Bernhard, Jean-Christophe aut Durand, Matthieu aut Ahallal, Youness aut Enthalten in World journal of urology Berlin : Springer, 1983 41(2021), 2 vom: 19. Feb., Seite 287-294 (DE-627)254910874 (DE-600)1463303-6 1433-8726 nnns volume:41 year:2021 number:2 day:19 month:02 pages:287-294 https://dx.doi.org/10.1007/s00345-020-03558-5 lizenzpflichtig Volltext GBV_USEFLAG_A SYSFLAG_A GBV_SPRINGER GBV_ILN_11 GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_32 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_69 GBV_ILN_70 GBV_ILN_73 GBV_ILN_74 GBV_ILN_90 GBV_ILN_95 GBV_ILN_100 GBV_ILN_101 GBV_ILN_105 GBV_ILN_110 GBV_ILN_120 GBV_ILN_138 GBV_ILN_150 GBV_ILN_151 GBV_ILN_152 GBV_ILN_161 GBV_ILN_170 GBV_ILN_171 GBV_ILN_187 GBV_ILN_213 GBV_ILN_224 GBV_ILN_230 GBV_ILN_250 GBV_ILN_267 GBV_ILN_281 GBV_ILN_285 GBV_ILN_293 GBV_ILN_370 GBV_ILN_602 GBV_ILN_636 GBV_ILN_702 GBV_ILN_711 GBV_ILN_2001 GBV_ILN_2003 GBV_ILN_2004 GBV_ILN_2005 GBV_ILN_2006 GBV_ILN_2007 GBV_ILN_2008 GBV_ILN_2009 GBV_ILN_2010 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2015 GBV_ILN_2020 GBV_ILN_2021 GBV_ILN_2025 GBV_ILN_2026 GBV_ILN_2027 GBV_ILN_2031 GBV_ILN_2034 GBV_ILN_2037 GBV_ILN_2038 GBV_ILN_2039 GBV_ILN_2044 GBV_ILN_2048 GBV_ILN_2049 GBV_ILN_2050 GBV_ILN_2055 GBV_ILN_2056 GBV_ILN_2057 GBV_ILN_2059 GBV_ILN_2061 GBV_ILN_2064 GBV_ILN_2065 GBV_ILN_2068 GBV_ILN_2088 GBV_ILN_2093 GBV_ILN_2106 GBV_ILN_2107 GBV_ILN_2108 GBV_ILN_2110 GBV_ILN_2111 GBV_ILN_2112 GBV_ILN_2113 GBV_ILN_2118 GBV_ILN_2122 GBV_ILN_2129 GBV_ILN_2143 GBV_ILN_2144 GBV_ILN_2147 GBV_ILN_2148 GBV_ILN_2152 GBV_ILN_2153 GBV_ILN_2188 GBV_ILN_2190 GBV_ILN_2232 GBV_ILN_2336 GBV_ILN_2446 GBV_ILN_2470 GBV_ILN_2472 GBV_ILN_2507 GBV_ILN_2522 GBV_ILN_2548 GBV_ILN_4035 GBV_ILN_4037 GBV_ILN_4046 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4242 GBV_ILN_4246 GBV_ILN_4249 GBV_ILN_4251 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4326 GBV_ILN_4328 GBV_ILN_4333 GBV_ILN_4334 GBV_ILN_4335 GBV_ILN_4336 GBV_ILN_4338 GBV_ILN_4393 GBV_ILN_4700 AR 41 2021 2 19 02 287-294 |
| allfieldsSound |
10.1007/s00345-020-03558-5 doi (DE-627)SPR049430823 (SPR)s00345-020-03558-5-e DE-627 ger DE-627 rakwb eng Mellouki, Adil verfasserin aut Evaluation of oncological outcomes of robotic partial nephrectomy according to the type of hilar control approach (On-clamp vs Off-clamp), a multicentric study of the French network of research on kidney cancer—UROCCR 58-NCT03293563 2021 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier © The Author(s), under exclusive licence to Springer-Verlag GmbH, DE part of Springer Nature 2021 Purpose To compare off-clamp vs on-clamp robotic partial nephrectomy (RPN) for renal cell carcinoma (RCC) in terms of oncological outcomes, and to assess the impact of surgical experience (SE). Methods We extracted data of a contemporary cohort of 1359 patients from the prospectively maintained database of the French national network of research on kidney cancer (UROCCR). The primary objective was to assess the positive surgical margin (PSM) rate. We also evaluated the oncological outcomes regardless of the surgical experience (SE) by dividing patients into three groups of SE as a secondary endpoints. SE was defined by the caseload of RPN per surgeon per year. For the continuous variables, we used Mann–Whitney and Student tests. We assessed survival analysis according to hilar control approach by Kaplan–Meier curves with log rank tests. A logistic regression multivariate analysis was used to evaluate the independent factors of PSM. Results Outcomes of 224 off-clamp RPN for RCC were compared to 1135 on-clamp RPN. PSM rate was not statistically different, with 5.6% in the off-clamp group, and 11% in the on-clamp group (p = 0.1). When assessing survival analysis for overall survival (OS), local recurrence-free survival (LR), and metastasis-free survival (MFS) according to hilar clamping approach, there were no statistically significant differences between the two groups with p value log rank = 0.2, 0.8, 0.1, respectively. In multivariate analysis assessing SE, hilar control approach, hospital volume (HV), RENAL score, gender, Age, ECOG, EBL, BMI, and indication of NSS, age at surgery was associated with PSM (odds ratio [OR] 1.03 (95% CI 1.00–1.04), 0.02), whereas SE, HV, and type of hilar control approach were not predictive factors of PSM. Conclusion Hilar control approach seems to have no impact on PSM of RPN for RCC. Our findings were consistent with randomized trials. Hilar control approach (dpeaa)DE-He213 Kidney cancer (dpeaa)DE-He213 Oncological outcomes (dpeaa)DE-He213 Positive surgical margins (dpeaa)DE-He213 Robotic partial nephrectomy (dpeaa)DE-He213 Bentellis, Imad aut Morrone, Arnoult aut Doumerc, Nicolas aut Beauval, Jean-Baptiste aut Roupret, Morgane aut Nouhaud, François-Xavier aut Lebacle, Cedric aut Long, Jean-Alexandre aut Chevallier, Daniel aut Tibi, Brannwel aut Shaikh, Aysha aut Imbert de la Phalecque, L. aut Pillot, Pierre aut Tillou, Xavier aut Bernhard, Jean-Christophe aut Durand, Matthieu aut Ahallal, Youness aut Enthalten in World journal of urology Berlin : Springer, 1983 41(2021), 2 vom: 19. Feb., Seite 287-294 (DE-627)254910874 (DE-600)1463303-6 1433-8726 nnns volume:41 year:2021 number:2 day:19 month:02 pages:287-294 https://dx.doi.org/10.1007/s00345-020-03558-5 lizenzpflichtig Volltext GBV_USEFLAG_A SYSFLAG_A GBV_SPRINGER GBV_ILN_11 GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_32 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_69 GBV_ILN_70 GBV_ILN_73 GBV_ILN_74 GBV_ILN_90 GBV_ILN_95 GBV_ILN_100 GBV_ILN_101 GBV_ILN_105 GBV_ILN_110 GBV_ILN_120 GBV_ILN_138 GBV_ILN_150 GBV_ILN_151 GBV_ILN_152 GBV_ILN_161 GBV_ILN_170 GBV_ILN_171 GBV_ILN_187 GBV_ILN_213 GBV_ILN_224 GBV_ILN_230 GBV_ILN_250 GBV_ILN_267 GBV_ILN_281 GBV_ILN_285 GBV_ILN_293 GBV_ILN_370 GBV_ILN_602 GBV_ILN_636 GBV_ILN_702 GBV_ILN_711 GBV_ILN_2001 GBV_ILN_2003 GBV_ILN_2004 GBV_ILN_2005 GBV_ILN_2006 GBV_ILN_2007 GBV_ILN_2008 GBV_ILN_2009 GBV_ILN_2010 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2015 GBV_ILN_2020 GBV_ILN_2021 GBV_ILN_2025 GBV_ILN_2026 GBV_ILN_2027 GBV_ILN_2031 GBV_ILN_2034 GBV_ILN_2037 GBV_ILN_2038 GBV_ILN_2039 GBV_ILN_2044 GBV_ILN_2048 GBV_ILN_2049 GBV_ILN_2050 GBV_ILN_2055 GBV_ILN_2056 GBV_ILN_2057 GBV_ILN_2059 GBV_ILN_2061 GBV_ILN_2064 GBV_ILN_2065 GBV_ILN_2068 GBV_ILN_2088 GBV_ILN_2093 GBV_ILN_2106 GBV_ILN_2107 GBV_ILN_2108 GBV_ILN_2110 GBV_ILN_2111 GBV_ILN_2112 GBV_ILN_2113 GBV_ILN_2118 GBV_ILN_2122 GBV_ILN_2129 GBV_ILN_2143 GBV_ILN_2144 GBV_ILN_2147 GBV_ILN_2148 GBV_ILN_2152 GBV_ILN_2153 GBV_ILN_2188 GBV_ILN_2190 GBV_ILN_2232 GBV_ILN_2336 GBV_ILN_2446 GBV_ILN_2470 GBV_ILN_2472 GBV_ILN_2507 GBV_ILN_2522 GBV_ILN_2548 GBV_ILN_4035 GBV_ILN_4037 GBV_ILN_4046 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4242 GBV_ILN_4246 GBV_ILN_4249 GBV_ILN_4251 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4326 GBV_ILN_4328 GBV_ILN_4333 GBV_ILN_4334 GBV_ILN_4335 GBV_ILN_4336 GBV_ILN_4338 GBV_ILN_4393 GBV_ILN_4700 AR 41 2021 2 19 02 287-294 |
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Enthalten in World journal of urology 41(2021), 2 vom: 19. Feb., Seite 287-294 volume:41 year:2021 number:2 day:19 month:02 pages:287-294 |
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Mellouki, Adil @@aut@@ Bentellis, Imad @@aut@@ Morrone, Arnoult @@aut@@ Doumerc, Nicolas @@aut@@ Beauval, Jean-Baptiste @@aut@@ Roupret, Morgane @@aut@@ Nouhaud, François-Xavier @@aut@@ Lebacle, Cedric @@aut@@ Long, Jean-Alexandre @@aut@@ Chevallier, Daniel @@aut@@ Tibi, Brannwel @@aut@@ Shaikh, Aysha @@aut@@ Imbert de la Phalecque, L. @@aut@@ Pillot, Pierre @@aut@@ Tillou, Xavier @@aut@@ Bernhard, Jean-Christophe @@aut@@ Durand, Matthieu @@aut@@ Ahallal, Youness @@aut@@ |
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Methods We extracted data of a contemporary cohort of 1359 patients from the prospectively maintained database of the French national network of research on kidney cancer (UROCCR). The primary objective was to assess the positive surgical margin (PSM) rate. We also evaluated the oncological outcomes regardless of the surgical experience (SE) by dividing patients into three groups of SE as a secondary endpoints. SE was defined by the caseload of RPN per surgeon per year. For the continuous variables, we used Mann–Whitney and Student tests. We assessed survival analysis according to hilar control approach by Kaplan–Meier curves with log rank tests. A logistic regression multivariate analysis was used to evaluate the independent factors of PSM. Results Outcomes of 224 off-clamp RPN for RCC were compared to 1135 on-clamp RPN. PSM rate was not statistically different, with 5.6% in the off-clamp group, and 11% in the on-clamp group (p = 0.1). When assessing survival analysis for overall survival (OS), local recurrence-free survival (LR), and metastasis-free survival (MFS) according to hilar clamping approach, there were no statistically significant differences between the two groups with p value log rank = 0.2, 0.8, 0.1, respectively. In multivariate analysis assessing SE, hilar control approach, hospital volume (HV), RENAL score, gender, Age, ECOG, EBL, BMI, and indication of NSS, age at surgery was associated with PSM (odds ratio [OR] 1.03 (95% CI 1.00–1.04), 0.02), whereas SE, HV, and type of hilar control approach were not predictive factors of PSM. Conclusion Hilar control approach seems to have no impact on PSM of RPN for RCC. 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| author |
Mellouki, Adil |
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Mellouki, Adil misc Hilar control approach misc Kidney cancer misc Oncological outcomes misc Positive surgical margins misc Robotic partial nephrectomy Evaluation of oncological outcomes of robotic partial nephrectomy according to the type of hilar control approach (On-clamp vs Off-clamp), a multicentric study of the French network of research on kidney cancer—UROCCR 58-NCT03293563 |
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Mellouki, Adil |
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1433-8726 |
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Evaluation of oncological outcomes of robotic partial nephrectomy according to the type of hilar control approach (On-clamp vs Off-clamp), a multicentric study of the French network of research on kidney cancer—UROCCR 58-NCT03293563 Hilar control approach (dpeaa)DE-He213 Kidney cancer (dpeaa)DE-He213 Oncological outcomes (dpeaa)DE-He213 Positive surgical margins (dpeaa)DE-He213 Robotic partial nephrectomy (dpeaa)DE-He213 |
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misc Hilar control approach misc Kidney cancer misc Oncological outcomes misc Positive surgical margins misc Robotic partial nephrectomy |
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misc Hilar control approach misc Kidney cancer misc Oncological outcomes misc Positive surgical margins misc Robotic partial nephrectomy |
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misc Hilar control approach misc Kidney cancer misc Oncological outcomes misc Positive surgical margins misc Robotic partial nephrectomy |
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Evaluation of oncological outcomes of robotic partial nephrectomy according to the type of hilar control approach (On-clamp vs Off-clamp), a multicentric study of the French network of research on kidney cancer—UROCCR 58-NCT03293563 |
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Evaluation of oncological outcomes of robotic partial nephrectomy according to the type of hilar control approach (On-clamp vs Off-clamp), a multicentric study of the French network of research on kidney cancer—UROCCR 58-NCT03293563 |
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Mellouki, Adil Bentellis, Imad Morrone, Arnoult Doumerc, Nicolas Beauval, Jean-Baptiste Roupret, Morgane Nouhaud, François-Xavier Lebacle, Cedric Long, Jean-Alexandre Chevallier, Daniel Tibi, Brannwel Shaikh, Aysha Imbert de la Phalecque, L. Pillot, Pierre Tillou, Xavier Bernhard, Jean-Christophe Durand, Matthieu Ahallal, Youness |
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10.1007/s00345-020-03558-5 |
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evaluation of oncological outcomes of robotic partial nephrectomy according to the type of hilar control approach (on-clamp vs off-clamp), a multicentric study of the french network of research on kidney cancer—uroccr 58-nct03293563 |
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Evaluation of oncological outcomes of robotic partial nephrectomy according to the type of hilar control approach (On-clamp vs Off-clamp), a multicentric study of the French network of research on kidney cancer—UROCCR 58-NCT03293563 |
| abstract |
Purpose To compare off-clamp vs on-clamp robotic partial nephrectomy (RPN) for renal cell carcinoma (RCC) in terms of oncological outcomes, and to assess the impact of surgical experience (SE). Methods We extracted data of a contemporary cohort of 1359 patients from the prospectively maintained database of the French national network of research on kidney cancer (UROCCR). The primary objective was to assess the positive surgical margin (PSM) rate. We also evaluated the oncological outcomes regardless of the surgical experience (SE) by dividing patients into three groups of SE as a secondary endpoints. SE was defined by the caseload of RPN per surgeon per year. For the continuous variables, we used Mann–Whitney and Student tests. We assessed survival analysis according to hilar control approach by Kaplan–Meier curves with log rank tests. A logistic regression multivariate analysis was used to evaluate the independent factors of PSM. Results Outcomes of 224 off-clamp RPN for RCC were compared to 1135 on-clamp RPN. PSM rate was not statistically different, with 5.6% in the off-clamp group, and 11% in the on-clamp group (p = 0.1). When assessing survival analysis for overall survival (OS), local recurrence-free survival (LR), and metastasis-free survival (MFS) according to hilar clamping approach, there were no statistically significant differences between the two groups with p value log rank = 0.2, 0.8, 0.1, respectively. In multivariate analysis assessing SE, hilar control approach, hospital volume (HV), RENAL score, gender, Age, ECOG, EBL, BMI, and indication of NSS, age at surgery was associated with PSM (odds ratio [OR] 1.03 (95% CI 1.00–1.04), 0.02), whereas SE, HV, and type of hilar control approach were not predictive factors of PSM. Conclusion Hilar control approach seems to have no impact on PSM of RPN for RCC. Our findings were consistent with randomized trials. © The Author(s), under exclusive licence to Springer-Verlag GmbH, DE part of Springer Nature 2021 |
| abstractGer |
Purpose To compare off-clamp vs on-clamp robotic partial nephrectomy (RPN) for renal cell carcinoma (RCC) in terms of oncological outcomes, and to assess the impact of surgical experience (SE). Methods We extracted data of a contemporary cohort of 1359 patients from the prospectively maintained database of the French national network of research on kidney cancer (UROCCR). The primary objective was to assess the positive surgical margin (PSM) rate. We also evaluated the oncological outcomes regardless of the surgical experience (SE) by dividing patients into three groups of SE as a secondary endpoints. SE was defined by the caseload of RPN per surgeon per year. For the continuous variables, we used Mann–Whitney and Student tests. We assessed survival analysis according to hilar control approach by Kaplan–Meier curves with log rank tests. A logistic regression multivariate analysis was used to evaluate the independent factors of PSM. Results Outcomes of 224 off-clamp RPN for RCC were compared to 1135 on-clamp RPN. PSM rate was not statistically different, with 5.6% in the off-clamp group, and 11% in the on-clamp group (p = 0.1). When assessing survival analysis for overall survival (OS), local recurrence-free survival (LR), and metastasis-free survival (MFS) according to hilar clamping approach, there were no statistically significant differences between the two groups with p value log rank = 0.2, 0.8, 0.1, respectively. In multivariate analysis assessing SE, hilar control approach, hospital volume (HV), RENAL score, gender, Age, ECOG, EBL, BMI, and indication of NSS, age at surgery was associated with PSM (odds ratio [OR] 1.03 (95% CI 1.00–1.04), 0.02), whereas SE, HV, and type of hilar control approach were not predictive factors of PSM. Conclusion Hilar control approach seems to have no impact on PSM of RPN for RCC. Our findings were consistent with randomized trials. © The Author(s), under exclusive licence to Springer-Verlag GmbH, DE part of Springer Nature 2021 |
| abstract_unstemmed |
Purpose To compare off-clamp vs on-clamp robotic partial nephrectomy (RPN) for renal cell carcinoma (RCC) in terms of oncological outcomes, and to assess the impact of surgical experience (SE). Methods We extracted data of a contemporary cohort of 1359 patients from the prospectively maintained database of the French national network of research on kidney cancer (UROCCR). The primary objective was to assess the positive surgical margin (PSM) rate. We also evaluated the oncological outcomes regardless of the surgical experience (SE) by dividing patients into three groups of SE as a secondary endpoints. SE was defined by the caseload of RPN per surgeon per year. For the continuous variables, we used Mann–Whitney and Student tests. We assessed survival analysis according to hilar control approach by Kaplan–Meier curves with log rank tests. A logistic regression multivariate analysis was used to evaluate the independent factors of PSM. Results Outcomes of 224 off-clamp RPN for RCC were compared to 1135 on-clamp RPN. PSM rate was not statistically different, with 5.6% in the off-clamp group, and 11% in the on-clamp group (p = 0.1). When assessing survival analysis for overall survival (OS), local recurrence-free survival (LR), and metastasis-free survival (MFS) according to hilar clamping approach, there were no statistically significant differences between the two groups with p value log rank = 0.2, 0.8, 0.1, respectively. In multivariate analysis assessing SE, hilar control approach, hospital volume (HV), RENAL score, gender, Age, ECOG, EBL, BMI, and indication of NSS, age at surgery was associated with PSM (odds ratio [OR] 1.03 (95% CI 1.00–1.04), 0.02), whereas SE, HV, and type of hilar control approach were not predictive factors of PSM. Conclusion Hilar control approach seems to have no impact on PSM of RPN for RCC. Our findings were consistent with randomized trials. © The Author(s), under exclusive licence to Springer-Verlag GmbH, DE part of Springer Nature 2021 |
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Evaluation of oncological outcomes of robotic partial nephrectomy according to the type of hilar control approach (On-clamp vs Off-clamp), a multicentric study of the French network of research on kidney cancer—UROCCR 58-NCT03293563 |
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Bentellis, Imad Morrone, Arnoult Doumerc, Nicolas Beauval, Jean-Baptiste Roupret, Morgane Nouhaud, François-Xavier Lebacle, Cedric Long, Jean-Alexandre Chevallier, Daniel Tibi, Brannwel Shaikh, Aysha Imbert de la Phalecque, L. Pillot, Pierre Tillou, Xavier Bernhard, Jean-Christophe Durand, Matthieu Ahallal, Youness |
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| score |
7.402669 |