Modulation of Slow Desensitization (Tachyphylaxis) of Acid-Sensing Ion Channel (ASIC)1a

Among the proton-activated channels of the ASIC family, ASIC1a exhibits a specific tachyphylaxis phenomenon in the form of a progressive decrease in the response amplitude during a series of activations. This process is well known, but its mechanism is poorly understood. Here, we demonstrated a part...
Ausführliche Beschreibung

Gespeichert in:
Autor*in:

Komarova, Margarita S. [verfasserIn]

Bukharev, Andrey R.

Potapieva, Natalia N.

Tikhonov, Denis B.

Format:

E-Artikel

Sprache:

Englisch

Erschienen:

2022

Schlagwörter:

Tachyphylaxis

Gating modulation

Voltage dependence

Calcium dependence

pH dependence

Anmerkung:

© The Author(s), under exclusive licence to Springer Science+Business Media, LLC, part of Springer Nature 2022

Übergeordnetes Werk:

Enthalten in: Cellular and molecular neurobiology - Dordrecht : Springer Science + Business Media B.V, 1981, 43(2022), 2 vom: 24. Feb., Seite 771-783

Übergeordnetes Werk:

volume:43 ; year:2022 ; number:2 ; day:24 ; month:02 ; pages:771-783

Links:

Volltext

DOI / URN:

10.1007/s10571-022-01207-6

Katalog-ID:

SPR049471449

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