Pseudo-hypoaldosteronism secondary to infantile urinary tract infections: role of ultrasound

Background The biochemical hallmarks of transient pseudo-hypoaldosteronism associated with a pyelonephritis include hyponatremia, hyperkalemia, and acidosis. We tested if the kidney-urinary tract ultrasound helps in predicting the diagnosis of overt pseudo-hypoaldosteronism in infants with a pyelone...
Ausführliche Beschreibung

Gespeichert in:

Autor*in:	Graziano, Noemi [verfasserIn] Agostoni, Carlo Chiaraviglio, Francesca Betti, Céline Piffer, Arianna Bianchetti, Mario G. Milani, Gregorio P.

Format:	E-Artikel
Sprache:	Englisch

Erschienen:	2022

Schlagwörter:	Hyponatremia Acidosis Pyelonephritis Infection Sonography Aldosterone; children; infants

Anmerkung:	© The Author(s) 2022

Übergeordnetes Werk:	Enthalten in: The Italian journal of pediatrics - London : BioMed Central, 2008, 48(2022), 1 vom: 24. Jan.
Übergeordnetes Werk:	volume:48 ; year:2022 ; number:1 ; day:24 ; month:01

Links:	Volltext

DOI / URN:	10.1186/s13052-022-01203-y

Katalog-ID:	SPR050437909

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520			\|a Background The biochemical hallmarks of transient pseudo-hypoaldosteronism associated with a pyelonephritis include hyponatremia, hyperkalemia, and acidosis. We tested if the kidney-urinary tract ultrasound helps in predicting the diagnosis of overt pseudo-hypoaldosteronism in infants with a pyelonephritis. Cases presentation Between 2013 and 2020, we managed 71 previously healthy infants 4 weeks to 24 months of age with a pyelonephritis (42 males and 29 females) and made the biochemical diagnosis of pseudo-hypoaldosteronism in 17 (24%). Infants with and without pseudo-hypoaldosteronism did not significantly differ with respect to the prevalence of kidney-urinary tract ultrasound abnormalities, graded by means of the UTD classification system of urinary tract abnormalities. Conclusions Kidney-urinary tract ultrasound is almost routinely obtained in children with a febrile urinary tract infection. Our experience does not support the hypothesis that ultrasound might be relevant for the diagnosis of overt transient pseudo-hypoaldosteronism in babies affected by a urinary tract infection. Our data confirm the assumption that negative studies may be important for advancing clinical practice.
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allfields	10.1186/s13052-022-01203-y doi (DE-627)SPR050437909 (SPR)s13052-022-01203-y-e DE-627 ger DE-627 rakwb eng Graziano, Noemi verfasserin aut Pseudo-hypoaldosteronism secondary to infantile urinary tract infections: role of ultrasound 2022 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier © The Author(s) 2022 Background The biochemical hallmarks of transient pseudo-hypoaldosteronism associated with a pyelonephritis include hyponatremia, hyperkalemia, and acidosis. We tested if the kidney-urinary tract ultrasound helps in predicting the diagnosis of overt pseudo-hypoaldosteronism in infants with a pyelonephritis. Cases presentation Between 2013 and 2020, we managed 71 previously healthy infants 4 weeks to 24 months of age with a pyelonephritis (42 males and 29 females) and made the biochemical diagnosis of pseudo-hypoaldosteronism in 17 (24%). Infants with and without pseudo-hypoaldosteronism did not significantly differ with respect to the prevalence of kidney-urinary tract ultrasound abnormalities, graded by means of the UTD classification system of urinary tract abnormalities. Conclusions Kidney-urinary tract ultrasound is almost routinely obtained in children with a febrile urinary tract infection. Our experience does not support the hypothesis that ultrasound might be relevant for the diagnosis of overt transient pseudo-hypoaldosteronism in babies affected by a urinary tract infection. Our data confirm the assumption that negative studies may be important for advancing clinical practice. Hyponatremia (dpeaa)DE-He213 Acidosis (dpeaa)DE-He213 Pyelonephritis (dpeaa)DE-He213 Infection (dpeaa)DE-He213 Sonography (dpeaa)DE-He213 Aldosterone; children; infants (dpeaa)DE-He213 Agostoni, Carlo (orcid)0000-0002-5006-0832 aut Chiaraviglio, Francesca aut Betti, Céline aut Piffer, Arianna aut Bianchetti, Mario G. aut Milani, Gregorio P. aut Enthalten in The Italian journal of pediatrics London : BioMed Central, 2008 48(2022), 1 vom: 24. Jan. (DE-627)352108029 (DE-600)2084688-5 1824-7288 nnns volume:48 year:2022 number:1 day:24 month:01 https://dx.doi.org/10.1186/s13052-022-01203-y kostenfrei Volltext GBV_USEFLAG_A SYSFLAG_A GBV_SPRINGER GBV_ILN_11 GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_2003 GBV_ILN_2005 GBV_ILN_2009 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2055 GBV_ILN_2111 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 48 2022 1 24 01
spelling	10.1186/s13052-022-01203-y doi (DE-627)SPR050437909 (SPR)s13052-022-01203-y-e DE-627 ger DE-627 rakwb eng Graziano, Noemi verfasserin aut Pseudo-hypoaldosteronism secondary to infantile urinary tract infections: role of ultrasound 2022 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier © The Author(s) 2022 Background The biochemical hallmarks of transient pseudo-hypoaldosteronism associated with a pyelonephritis include hyponatremia, hyperkalemia, and acidosis. We tested if the kidney-urinary tract ultrasound helps in predicting the diagnosis of overt pseudo-hypoaldosteronism in infants with a pyelonephritis. Cases presentation Between 2013 and 2020, we managed 71 previously healthy infants 4 weeks to 24 months of age with a pyelonephritis (42 males and 29 females) and made the biochemical diagnosis of pseudo-hypoaldosteronism in 17 (24%). Infants with and without pseudo-hypoaldosteronism did not significantly differ with respect to the prevalence of kidney-urinary tract ultrasound abnormalities, graded by means of the UTD classification system of urinary tract abnormalities. Conclusions Kidney-urinary tract ultrasound is almost routinely obtained in children with a febrile urinary tract infection. Our experience does not support the hypothesis that ultrasound might be relevant for the diagnosis of overt transient pseudo-hypoaldosteronism in babies affected by a urinary tract infection. Our data confirm the assumption that negative studies may be important for advancing clinical practice. Hyponatremia (dpeaa)DE-He213 Acidosis (dpeaa)DE-He213 Pyelonephritis (dpeaa)DE-He213 Infection (dpeaa)DE-He213 Sonography (dpeaa)DE-He213 Aldosterone; children; infants (dpeaa)DE-He213 Agostoni, Carlo (orcid)0000-0002-5006-0832 aut Chiaraviglio, Francesca aut Betti, Céline aut Piffer, Arianna aut Bianchetti, Mario G. aut Milani, Gregorio P. aut Enthalten in The Italian journal of pediatrics London : BioMed Central, 2008 48(2022), 1 vom: 24. Jan. (DE-627)352108029 (DE-600)2084688-5 1824-7288 nnns volume:48 year:2022 number:1 day:24 month:01 https://dx.doi.org/10.1186/s13052-022-01203-y kostenfrei Volltext GBV_USEFLAG_A SYSFLAG_A GBV_SPRINGER GBV_ILN_11 GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_2003 GBV_ILN_2005 GBV_ILN_2009 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2055 GBV_ILN_2111 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 48 2022 1 24 01
allfields_unstemmed	10.1186/s13052-022-01203-y doi (DE-627)SPR050437909 (SPR)s13052-022-01203-y-e DE-627 ger DE-627 rakwb eng Graziano, Noemi verfasserin aut Pseudo-hypoaldosteronism secondary to infantile urinary tract infections: role of ultrasound 2022 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier © The Author(s) 2022 Background The biochemical hallmarks of transient pseudo-hypoaldosteronism associated with a pyelonephritis include hyponatremia, hyperkalemia, and acidosis. We tested if the kidney-urinary tract ultrasound helps in predicting the diagnosis of overt pseudo-hypoaldosteronism in infants with a pyelonephritis. Cases presentation Between 2013 and 2020, we managed 71 previously healthy infants 4 weeks to 24 months of age with a pyelonephritis (42 males and 29 females) and made the biochemical diagnosis of pseudo-hypoaldosteronism in 17 (24%). Infants with and without pseudo-hypoaldosteronism did not significantly differ with respect to the prevalence of kidney-urinary tract ultrasound abnormalities, graded by means of the UTD classification system of urinary tract abnormalities. Conclusions Kidney-urinary tract ultrasound is almost routinely obtained in children with a febrile urinary tract infection. Our experience does not support the hypothesis that ultrasound might be relevant for the diagnosis of overt transient pseudo-hypoaldosteronism in babies affected by a urinary tract infection. Our data confirm the assumption that negative studies may be important for advancing clinical practice. Hyponatremia (dpeaa)DE-He213 Acidosis (dpeaa)DE-He213 Pyelonephritis (dpeaa)DE-He213 Infection (dpeaa)DE-He213 Sonography (dpeaa)DE-He213 Aldosterone; children; infants (dpeaa)DE-He213 Agostoni, Carlo (orcid)0000-0002-5006-0832 aut Chiaraviglio, Francesca aut Betti, Céline aut Piffer, Arianna aut Bianchetti, Mario G. aut Milani, Gregorio P. aut Enthalten in The Italian journal of pediatrics London : BioMed Central, 2008 48(2022), 1 vom: 24. Jan. (DE-627)352108029 (DE-600)2084688-5 1824-7288 nnns volume:48 year:2022 number:1 day:24 month:01 https://dx.doi.org/10.1186/s13052-022-01203-y kostenfrei Volltext GBV_USEFLAG_A SYSFLAG_A GBV_SPRINGER GBV_ILN_11 GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_2003 GBV_ILN_2005 GBV_ILN_2009 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2055 GBV_ILN_2111 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 48 2022 1 24 01
allfieldsGer	10.1186/s13052-022-01203-y doi (DE-627)SPR050437909 (SPR)s13052-022-01203-y-e DE-627 ger DE-627 rakwb eng Graziano, Noemi verfasserin aut Pseudo-hypoaldosteronism secondary to infantile urinary tract infections: role of ultrasound 2022 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier © The Author(s) 2022 Background The biochemical hallmarks of transient pseudo-hypoaldosteronism associated with a pyelonephritis include hyponatremia, hyperkalemia, and acidosis. We tested if the kidney-urinary tract ultrasound helps in predicting the diagnosis of overt pseudo-hypoaldosteronism in infants with a pyelonephritis. Cases presentation Between 2013 and 2020, we managed 71 previously healthy infants 4 weeks to 24 months of age with a pyelonephritis (42 males and 29 females) and made the biochemical diagnosis of pseudo-hypoaldosteronism in 17 (24%). Infants with and without pseudo-hypoaldosteronism did not significantly differ with respect to the prevalence of kidney-urinary tract ultrasound abnormalities, graded by means of the UTD classification system of urinary tract abnormalities. Conclusions Kidney-urinary tract ultrasound is almost routinely obtained in children with a febrile urinary tract infection. Our experience does not support the hypothesis that ultrasound might be relevant for the diagnosis of overt transient pseudo-hypoaldosteronism in babies affected by a urinary tract infection. Our data confirm the assumption that negative studies may be important for advancing clinical practice. Hyponatremia (dpeaa)DE-He213 Acidosis (dpeaa)DE-He213 Pyelonephritis (dpeaa)DE-He213 Infection (dpeaa)DE-He213 Sonography (dpeaa)DE-He213 Aldosterone; children; infants (dpeaa)DE-He213 Agostoni, Carlo (orcid)0000-0002-5006-0832 aut Chiaraviglio, Francesca aut Betti, Céline aut Piffer, Arianna aut Bianchetti, Mario G. aut Milani, Gregorio P. aut Enthalten in The Italian journal of pediatrics London : BioMed Central, 2008 48(2022), 1 vom: 24. Jan. (DE-627)352108029 (DE-600)2084688-5 1824-7288 nnns volume:48 year:2022 number:1 day:24 month:01 https://dx.doi.org/10.1186/s13052-022-01203-y kostenfrei Volltext GBV_USEFLAG_A SYSFLAG_A GBV_SPRINGER GBV_ILN_11 GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_2003 GBV_ILN_2005 GBV_ILN_2009 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2055 GBV_ILN_2111 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 48 2022 1 24 01
allfieldsSound	10.1186/s13052-022-01203-y doi (DE-627)SPR050437909 (SPR)s13052-022-01203-y-e DE-627 ger DE-627 rakwb eng Graziano, Noemi verfasserin aut Pseudo-hypoaldosteronism secondary to infantile urinary tract infections: role of ultrasound 2022 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier © The Author(s) 2022 Background The biochemical hallmarks of transient pseudo-hypoaldosteronism associated with a pyelonephritis include hyponatremia, hyperkalemia, and acidosis. We tested if the kidney-urinary tract ultrasound helps in predicting the diagnosis of overt pseudo-hypoaldosteronism in infants with a pyelonephritis. Cases presentation Between 2013 and 2020, we managed 71 previously healthy infants 4 weeks to 24 months of age with a pyelonephritis (42 males and 29 females) and made the biochemical diagnosis of pseudo-hypoaldosteronism in 17 (24%). Infants with and without pseudo-hypoaldosteronism did not significantly differ with respect to the prevalence of kidney-urinary tract ultrasound abnormalities, graded by means of the UTD classification system of urinary tract abnormalities. Conclusions Kidney-urinary tract ultrasound is almost routinely obtained in children with a febrile urinary tract infection. Our experience does not support the hypothesis that ultrasound might be relevant for the diagnosis of overt transient pseudo-hypoaldosteronism in babies affected by a urinary tract infection. Our data confirm the assumption that negative studies may be important for advancing clinical practice. Hyponatremia (dpeaa)DE-He213 Acidosis (dpeaa)DE-He213 Pyelonephritis (dpeaa)DE-He213 Infection (dpeaa)DE-He213 Sonography (dpeaa)DE-He213 Aldosterone; children; infants (dpeaa)DE-He213 Agostoni, Carlo (orcid)0000-0002-5006-0832 aut Chiaraviglio, Francesca aut Betti, Céline aut Piffer, Arianna aut Bianchetti, Mario G. aut Milani, Gregorio P. aut Enthalten in The Italian journal of pediatrics London : BioMed Central, 2008 48(2022), 1 vom: 24. Jan. (DE-627)352108029 (DE-600)2084688-5 1824-7288 nnns volume:48 year:2022 number:1 day:24 month:01 https://dx.doi.org/10.1186/s13052-022-01203-y kostenfrei Volltext GBV_USEFLAG_A SYSFLAG_A GBV_SPRINGER GBV_ILN_11 GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_2003 GBV_ILN_2005 GBV_ILN_2009 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2055 GBV_ILN_2111 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 48 2022 1 24 01
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source	Enthalten in The Italian journal of pediatrics 48(2022), 1 vom: 24. Jan. volume:48 year:2022 number:1 day:24 month:01
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author	Graziano, Noemi
spellingShingle	Graziano, Noemi misc Hyponatremia misc Acidosis misc Pyelonephritis misc Infection misc Sonography misc Aldosterone; children; infants Pseudo-hypoaldosteronism secondary to infantile urinary tract infections: role of ultrasound
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topic_title	Pseudo-hypoaldosteronism secondary to infantile urinary tract infections: role of ultrasound Hyponatremia (dpeaa)DE-He213 Acidosis (dpeaa)DE-He213 Pyelonephritis (dpeaa)DE-He213 Infection (dpeaa)DE-He213 Sonography (dpeaa)DE-He213 Aldosterone; children; infants (dpeaa)DE-He213
topic	misc Hyponatremia misc Acidosis misc Pyelonephritis misc Infection misc Sonography misc Aldosterone; children; infants
topic_unstemmed	misc Hyponatremia misc Acidosis misc Pyelonephritis misc Infection misc Sonography misc Aldosterone; children; infants
topic_browse	misc Hyponatremia misc Acidosis misc Pyelonephritis misc Infection misc Sonography misc Aldosterone; children; infants
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title	Pseudo-hypoaldosteronism secondary to infantile urinary tract infections: role of ultrasound
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title_full	Pseudo-hypoaldosteronism secondary to infantile urinary tract infections: role of ultrasound
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journal	The Italian journal of pediatrics
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author_browse	Graziano, Noemi Agostoni, Carlo Chiaraviglio, Francesca Betti, Céline Piffer, Arianna Bianchetti, Mario G. Milani, Gregorio P.
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title_sort	pseudo-hypoaldosteronism secondary to infantile urinary tract infections: role of ultrasound
title_auth	Pseudo-hypoaldosteronism secondary to infantile urinary tract infections: role of ultrasound
abstract	Background The biochemical hallmarks of transient pseudo-hypoaldosteronism associated with a pyelonephritis include hyponatremia, hyperkalemia, and acidosis. We tested if the kidney-urinary tract ultrasound helps in predicting the diagnosis of overt pseudo-hypoaldosteronism in infants with a pyelonephritis. Cases presentation Between 2013 and 2020, we managed 71 previously healthy infants 4 weeks to 24 months of age with a pyelonephritis (42 males and 29 females) and made the biochemical diagnosis of pseudo-hypoaldosteronism in 17 (24%). Infants with and without pseudo-hypoaldosteronism did not significantly differ with respect to the prevalence of kidney-urinary tract ultrasound abnormalities, graded by means of the UTD classification system of urinary tract abnormalities. Conclusions Kidney-urinary tract ultrasound is almost routinely obtained in children with a febrile urinary tract infection. Our experience does not support the hypothesis that ultrasound might be relevant for the diagnosis of overt transient pseudo-hypoaldosteronism in babies affected by a urinary tract infection. Our data confirm the assumption that negative studies may be important for advancing clinical practice. © The Author(s) 2022
abstractGer	Background The biochemical hallmarks of transient pseudo-hypoaldosteronism associated with a pyelonephritis include hyponatremia, hyperkalemia, and acidosis. We tested if the kidney-urinary tract ultrasound helps in predicting the diagnosis of overt pseudo-hypoaldosteronism in infants with a pyelonephritis. Cases presentation Between 2013 and 2020, we managed 71 previously healthy infants 4 weeks to 24 months of age with a pyelonephritis (42 males and 29 females) and made the biochemical diagnosis of pseudo-hypoaldosteronism in 17 (24%). Infants with and without pseudo-hypoaldosteronism did not significantly differ with respect to the prevalence of kidney-urinary tract ultrasound abnormalities, graded by means of the UTD classification system of urinary tract abnormalities. Conclusions Kidney-urinary tract ultrasound is almost routinely obtained in children with a febrile urinary tract infection. Our experience does not support the hypothesis that ultrasound might be relevant for the diagnosis of overt transient pseudo-hypoaldosteronism in babies affected by a urinary tract infection. Our data confirm the assumption that negative studies may be important for advancing clinical practice. © The Author(s) 2022
abstract_unstemmed	Background The biochemical hallmarks of transient pseudo-hypoaldosteronism associated with a pyelonephritis include hyponatremia, hyperkalemia, and acidosis. We tested if the kidney-urinary tract ultrasound helps in predicting the diagnosis of overt pseudo-hypoaldosteronism in infants with a pyelonephritis. Cases presentation Between 2013 and 2020, we managed 71 previously healthy infants 4 weeks to 24 months of age with a pyelonephritis (42 males and 29 females) and made the biochemical diagnosis of pseudo-hypoaldosteronism in 17 (24%). Infants with and without pseudo-hypoaldosteronism did not significantly differ with respect to the prevalence of kidney-urinary tract ultrasound abnormalities, graded by means of the UTD classification system of urinary tract abnormalities. Conclusions Kidney-urinary tract ultrasound is almost routinely obtained in children with a febrile urinary tract infection. Our experience does not support the hypothesis that ultrasound might be relevant for the diagnosis of overt transient pseudo-hypoaldosteronism in babies affected by a urinary tract infection. Our data confirm the assumption that negative studies may be important for advancing clinical practice. © The Author(s) 2022
collection_details	GBV_USEFLAG_A SYSFLAG_A GBV_SPRINGER GBV_ILN_11 GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_2003 GBV_ILN_2005 GBV_ILN_2009 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2055 GBV_ILN_2111 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700
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title_short	Pseudo-hypoaldosteronism secondary to infantile urinary tract infections: role of ultrasound
url	https://dx.doi.org/10.1186/s13052-022-01203-y
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author2	Agostoni, Carlo Chiaraviglio, Francesca Betti, Céline Piffer, Arianna Bianchetti, Mario G. Milani, Gregorio P.
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up_date	2024-07-03T15:32:27.923Z
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We tested if the kidney-urinary tract ultrasound helps in predicting the diagnosis of overt pseudo-hypoaldosteronism in infants with a pyelonephritis. Cases presentation Between 2013 and 2020, we managed 71 previously healthy infants 4 weeks to 24 months of age with a pyelonephritis (42 males and 29 females) and made the biochemical diagnosis of pseudo-hypoaldosteronism in 17 (24%). Infants with and without pseudo-hypoaldosteronism did not significantly differ with respect to the prevalence of kidney-urinary tract ultrasound abnormalities, graded by means of the UTD classification system of urinary tract abnormalities. Conclusions Kidney-urinary tract ultrasound is almost routinely obtained in children with a febrile urinary tract infection. Our experience does not support the hypothesis that ultrasound might be relevant for the diagnosis of overt transient pseudo-hypoaldosteronism in babies affected by a urinary tract infection. 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Pseudo-hypoaldosteronism secondary to infantile urinary tract infections: role of ultrasound

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