Doping Gd3+ Ion in PDA-PHBV Coating on Ti6Al4V Alloy for Enhancing Corrosion Resistance and Proliferation of Human Gingival Fibroblasts and Human Umbilical Vein Endothelial Cells

Abstract In this study, we fabricated poly(3-hydroxybutyrate-3-hydroxyvalerate) (PHBV) coatings doped with $ Gd^{3+} $ (1, 5, and 10 × $ 10^{−4} $ mol/L) on Ti6Al4V alloy for the first time to promote soft tissue sealing around dental implants. The corrosion resistance of $ Gd^{3+} $-modified PHBV-c...
Ausführliche Beschreibung

Gespeichert in:

Autor*in:	Qin, Sijie [verfasserIn] Xu, Xiongcheng Lu, Yanjin Li, Liu Huang, Tingting Lin, Jinxin

Format:	E-Artikel
Sprache:	Englisch

Erschienen:	2021

Schlagwörter:	Soft tissue sealing Poly(3-hydroxybutyrate-3-hydroxyvalerate) (PHBV) Gd Corrosion resistance Human gingival fibroblasts

Anmerkung:	© The Chinese Society for Metals (CSM) and Springer-Verlag GmbH Germany, part of Springer Nature 2021

Übergeordnetes Werk:	Enthalten in: Acta metallurgica Sinica - Beijing : Springer, 1988, 35(2021), 5 vom: 30. Juli, Seite 812-824
Übergeordnetes Werk:	volume:35 ; year:2021 ; number:5 ; day:30 ; month:07 ; pages:812-824

Links:	Volltext

DOI / URN:	10.1007/s40195-021-01292-4

Katalog-ID:	SPR050611232

Internformat


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245	1	0	\|a Doping Gd3+ Ion in PDA-PHBV Coating on Ti6Al4V Alloy for Enhancing Corrosion Resistance and Proliferation of Human Gingival Fibroblasts and Human Umbilical Vein Endothelial Cells
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520			\|a Abstract In this study, we fabricated poly(3-hydroxybutyrate-3-hydroxyvalerate) (PHBV) coatings doped with $ Gd^{3+} $ (1, 5, and 10 × $ 10^{−4} $ mol/L) on Ti6Al4V alloy for the first time to promote soft tissue sealing around dental implants. The corrosion resistance of $ Gd^{3+} $-modified PHBV-coated Ti6Al4V was studied by electrochemical and immersion tests, respectively, whereas CCK-8 and RT-PCR evaluated the biocompatibility to human gingival fibroblasts (HGFs) and human umbilical vein endothelial cells (HUVECs). It was found that the $ Gd^{3+} $-modified PHBV coating could enhance the corrosion resistance of Ti6Al4V. In vitro cell tests showed that PHBV coatings with and without $ Gd^{3+} $ addition could promote adhesion and proliferation of HGFs and HUVECs, showing a $ Gd^{3+} $ content-dependent manner. Moreover, it was found that the PDA-PHBV1Gd showed the best proliferation to HGFs by up-regulating gene expressions of VINCULIN, ITGB1, and ITGA3, whereas the best response to HUVECs with the highest gene expression of eNOS and HIF-1α genes was found in the PDA-PHBV@5Gd-coated group.
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650		4	\|a Human gingival fibroblasts \|7 (dpeaa)DE-He213
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700	1		\|a Lin, Jinxin \|4 aut
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912			\|a GBV_USEFLAG_A
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912			\|a GBV_ILN_22
912			\|a GBV_ILN_23
912			\|a GBV_ILN_24
912			\|a GBV_ILN_31
912			\|a GBV_ILN_32
912			\|a GBV_ILN_39
912			\|a GBV_ILN_40
912			\|a GBV_ILN_60
912			\|a GBV_ILN_62
912			\|a GBV_ILN_63
912			\|a GBV_ILN_65
912			\|a GBV_ILN_69
912			\|a GBV_ILN_70
912			\|a GBV_ILN_73
912			\|a GBV_ILN_74
912			\|a GBV_ILN_90
912			\|a GBV_ILN_95
912			\|a GBV_ILN_100
912			\|a GBV_ILN_105
912			\|a GBV_ILN_110
912			\|a GBV_ILN_120
912			\|a GBV_ILN_121
912			\|a GBV_ILN_138
912			\|a GBV_ILN_150
912			\|a GBV_ILN_151
912			\|a GBV_ILN_152
912			\|a GBV_ILN_161
912			\|a GBV_ILN_170
912			\|a GBV_ILN_171
912			\|a GBV_ILN_187
912			\|a GBV_ILN_206
912			\|a GBV_ILN_213
912			\|a GBV_ILN_224
912			\|a GBV_ILN_230
912			\|a GBV_ILN_250
912			\|a GBV_ILN_281
912			\|a GBV_ILN_285
912			\|a GBV_ILN_293
912			\|a GBV_ILN_370
912			\|a GBV_ILN_374
912			\|a GBV_ILN_602
912			\|a GBV_ILN_636
912			\|a GBV_ILN_647
912			\|a GBV_ILN_702
912			\|a GBV_ILN_2001
912			\|a GBV_ILN_2003
912			\|a GBV_ILN_2004
912			\|a GBV_ILN_2005
912			\|a GBV_ILN_2006
912			\|a GBV_ILN_2007
912			\|a GBV_ILN_2008
912			\|a GBV_ILN_2009
912			\|a GBV_ILN_2010
912			\|a GBV_ILN_2011
912			\|a GBV_ILN_2014
912			\|a GBV_ILN_2015
912			\|a GBV_ILN_2018
912			\|a GBV_ILN_2020
912			\|a GBV_ILN_2021
912			\|a GBV_ILN_2025
912			\|a GBV_ILN_2026
912			\|a GBV_ILN_2027
912			\|a GBV_ILN_2031
912			\|a GBV_ILN_2034
912			\|a GBV_ILN_2036
912			\|a GBV_ILN_2037
912			\|a GBV_ILN_2038
912			\|a GBV_ILN_2039
912			\|a GBV_ILN_2044
912			\|a GBV_ILN_2048
912			\|a GBV_ILN_2049
912			\|a GBV_ILN_2050
912			\|a GBV_ILN_2055
912			\|a GBV_ILN_2056
912			\|a GBV_ILN_2057
912			\|a GBV_ILN_2059
912			\|a GBV_ILN_2061
912			\|a GBV_ILN_2064
912			\|a GBV_ILN_2065
912			\|a GBV_ILN_2068
912			\|a GBV_ILN_2088
912			\|a GBV_ILN_2093
912			\|a GBV_ILN_2106
912			\|a GBV_ILN_2107
912			\|a GBV_ILN_2108
912			\|a GBV_ILN_2110
912			\|a GBV_ILN_2111
912			\|a GBV_ILN_2112
912			\|a GBV_ILN_2113
912			\|a GBV_ILN_2118
912			\|a GBV_ILN_2119
912			\|a GBV_ILN_2122
912			\|a GBV_ILN_2129
912			\|a GBV_ILN_2143
912			\|a GBV_ILN_2144
912			\|a GBV_ILN_2147
912			\|a GBV_ILN_2148
912			\|a GBV_ILN_2152
912			\|a GBV_ILN_2153
912			\|a GBV_ILN_2188
912			\|a GBV_ILN_2190
912			\|a GBV_ILN_2232
912			\|a GBV_ILN_2336
912			\|a GBV_ILN_2446
912			\|a GBV_ILN_2470
912			\|a GBV_ILN_2472
912			\|a GBV_ILN_2507
912			\|a GBV_ILN_2522
912			\|a GBV_ILN_2548
912			\|a GBV_ILN_2700
912			\|a GBV_ILN_2817
912			\|a GBV_ILN_4012
912			\|a GBV_ILN_4035
912			\|a GBV_ILN_4037
912			\|a GBV_ILN_4046
912			\|a GBV_ILN_4112
912			\|a GBV_ILN_4125
912			\|a GBV_ILN_4126
912			\|a GBV_ILN_4242
912			\|a GBV_ILN_4246
912			\|a GBV_ILN_4249
912			\|a GBV_ILN_4251
912			\|a GBV_ILN_4277
912			\|a GBV_ILN_4305
912			\|a GBV_ILN_4306
912			\|a GBV_ILN_4307
912			\|a GBV_ILN_4313
912			\|a GBV_ILN_4322
912			\|a GBV_ILN_4323
912			\|a GBV_ILN_4324
912			\|a GBV_ILN_4325
912			\|a GBV_ILN_4326
912			\|a GBV_ILN_4328
912			\|a GBV_ILN_4333
912			\|a GBV_ILN_4334
912			\|a GBV_ILN_4335
912			\|a GBV_ILN_4336
912			\|a GBV_ILN_4338
912			\|a GBV_ILN_4346
912			\|a GBV_ILN_4367
912			\|a GBV_ILN_4392
912			\|a GBV_ILN_4393
912			\|a GBV_ILN_4700
912			\|a GBV_ILN_4753
951			\|a AR
952			\|d 35 \|j 2021 \|e 5 \|b 30 \|c 07 \|h 812-824

Indexfelder

author_variant	s q sq x x xx y l yl l l ll t h th j l jl
matchkey_str	article:21941289:2021----::oigdinndpbcaignia4alyoehnigorsorssacadrlfrtoohmnigvlirbat
hierarchy_sort_str	2021
publishDate	2021
allfields	10.1007/s40195-021-01292-4 doi (DE-627)SPR050611232 (SPR)s40195-021-01292-4-e DE-627 ger DE-627 rakwb eng Qin, Sijie verfasserin aut Doping Gd3+ Ion in PDA-PHBV Coating on Ti6Al4V Alloy for Enhancing Corrosion Resistance and Proliferation of Human Gingival Fibroblasts and Human Umbilical Vein Endothelial Cells 2021 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier © The Chinese Society for Metals (CSM) and Springer-Verlag GmbH Germany, part of Springer Nature 2021 Abstract In this study, we fabricated poly(3-hydroxybutyrate-3-hydroxyvalerate) (PHBV) coatings doped with $ Gd^{3+} $ (1, 5, and 10 × $ 10^{−4} $ mol/L) on Ti6Al4V alloy for the first time to promote soft tissue sealing around dental implants. The corrosion resistance of $ Gd^{3+} $-modified PHBV-coated Ti6Al4V was studied by electrochemical and immersion tests, respectively, whereas CCK-8 and RT-PCR evaluated the biocompatibility to human gingival fibroblasts (HGFs) and human umbilical vein endothelial cells (HUVECs). It was found that the $ Gd^{3+} $-modified PHBV coating could enhance the corrosion resistance of Ti6Al4V. In vitro cell tests showed that PHBV coatings with and without $ Gd^{3+} $ addition could promote adhesion and proliferation of HGFs and HUVECs, showing a $ Gd^{3+} $ content-dependent manner. Moreover, it was found that the PDA-PHBV1Gd showed the best proliferation to HGFs by up-regulating gene expressions of VINCULIN, ITGB1, and ITGA3, whereas the best response to HUVECs with the highest gene expression of eNOS and HIF-1α genes was found in the PDA-PHBV@5Gd-coated group. Soft tissue sealing (dpeaa)DE-He213 Poly(3-hydroxybutyrate-3-hydroxyvalerate) (PHBV) (dpeaa)DE-He213 Gd (dpeaa)DE-He213 Corrosion resistance (dpeaa)DE-He213 Human gingival fibroblasts (dpeaa)DE-He213 Xu, Xiongcheng aut Lu, Yanjin aut Li, Liu aut Huang, Tingting aut Lin, Jinxin aut Enthalten in Acta metallurgica Sinica Beijing : Springer, 1988 35(2021), 5 vom: 30. Juli, Seite 812-824 (DE-627)513220216 (DE-600)2238871-0 2194-1289 nnns volume:35 year:2021 number:5 day:30 month:07 pages:812-824 https://dx.doi.org/10.1007/s40195-021-01292-4 lizenzpflichtig Volltext GBV_USEFLAG_A SYSFLAG_A GBV_SPRINGER GBV_ILN_11 GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_32 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_70 GBV_ILN_73 GBV_ILN_74 GBV_ILN_90 GBV_ILN_95 GBV_ILN_100 GBV_ILN_105 GBV_ILN_110 GBV_ILN_120 GBV_ILN_121 GBV_ILN_138 GBV_ILN_150 GBV_ILN_151 GBV_ILN_152 GBV_ILN_161 GBV_ILN_170 GBV_ILN_171 GBV_ILN_187 GBV_ILN_206 GBV_ILN_213 GBV_ILN_224 GBV_ILN_230 GBV_ILN_250 GBV_ILN_281 GBV_ILN_285 GBV_ILN_293 GBV_ILN_370 GBV_ILN_374 GBV_ILN_602 GBV_ILN_636 GBV_ILN_647 GBV_ILN_702 GBV_ILN_2001 GBV_ILN_2003 GBV_ILN_2004 GBV_ILN_2005 GBV_ILN_2006 GBV_ILN_2007 GBV_ILN_2008 GBV_ILN_2009 GBV_ILN_2010 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2015 GBV_ILN_2018 GBV_ILN_2020 GBV_ILN_2021 GBV_ILN_2025 GBV_ILN_2026 GBV_ILN_2027 GBV_ILN_2031 GBV_ILN_2034 GBV_ILN_2036 GBV_ILN_2037 GBV_ILN_2038 GBV_ILN_2039 GBV_ILN_2044 GBV_ILN_2048 GBV_ILN_2049 GBV_ILN_2050 GBV_ILN_2055 GBV_ILN_2056 GBV_ILN_2057 GBV_ILN_2059 GBV_ILN_2061 GBV_ILN_2064 GBV_ILN_2065 GBV_ILN_2068 GBV_ILN_2088 GBV_ILN_2093 GBV_ILN_2106 GBV_ILN_2107 GBV_ILN_2108 GBV_ILN_2110 GBV_ILN_2111 GBV_ILN_2112 GBV_ILN_2113 GBV_ILN_2118 GBV_ILN_2119 GBV_ILN_2122 GBV_ILN_2129 GBV_ILN_2143 GBV_ILN_2144 GBV_ILN_2147 GBV_ILN_2148 GBV_ILN_2152 GBV_ILN_2153 GBV_ILN_2188 GBV_ILN_2190 GBV_ILN_2232 GBV_ILN_2336 GBV_ILN_2446 GBV_ILN_2470 GBV_ILN_2472 GBV_ILN_2507 GBV_ILN_2522 GBV_ILN_2548 GBV_ILN_2700 GBV_ILN_2817 GBV_ILN_4012 GBV_ILN_4035 GBV_ILN_4037 GBV_ILN_4046 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4242 GBV_ILN_4246 GBV_ILN_4249 GBV_ILN_4251 GBV_ILN_4277 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4326 GBV_ILN_4328 GBV_ILN_4333 GBV_ILN_4334 GBV_ILN_4335 GBV_ILN_4336 GBV_ILN_4338 GBV_ILN_4346 GBV_ILN_4367 GBV_ILN_4392 GBV_ILN_4393 GBV_ILN_4700 GBV_ILN_4753 AR 35 2021 5 30 07 812-824
spelling	10.1007/s40195-021-01292-4 doi (DE-627)SPR050611232 (SPR)s40195-021-01292-4-e DE-627 ger DE-627 rakwb eng Qin, Sijie verfasserin aut Doping Gd3+ Ion in PDA-PHBV Coating on Ti6Al4V Alloy for Enhancing Corrosion Resistance and Proliferation of Human Gingival Fibroblasts and Human Umbilical Vein Endothelial Cells 2021 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier © The Chinese Society for Metals (CSM) and Springer-Verlag GmbH Germany, part of Springer Nature 2021 Abstract In this study, we fabricated poly(3-hydroxybutyrate-3-hydroxyvalerate) (PHBV) coatings doped with $ Gd^{3+} $ (1, 5, and 10 × $ 10^{−4} $ mol/L) on Ti6Al4V alloy for the first time to promote soft tissue sealing around dental implants. The corrosion resistance of $ Gd^{3+} $-modified PHBV-coated Ti6Al4V was studied by electrochemical and immersion tests, respectively, whereas CCK-8 and RT-PCR evaluated the biocompatibility to human gingival fibroblasts (HGFs) and human umbilical vein endothelial cells (HUVECs). It was found that the $ Gd^{3+} $-modified PHBV coating could enhance the corrosion resistance of Ti6Al4V. In vitro cell tests showed that PHBV coatings with and without $ Gd^{3+} $ addition could promote adhesion and proliferation of HGFs and HUVECs, showing a $ Gd^{3+} $ content-dependent manner. Moreover, it was found that the PDA-PHBV1Gd showed the best proliferation to HGFs by up-regulating gene expressions of VINCULIN, ITGB1, and ITGA3, whereas the best response to HUVECs with the highest gene expression of eNOS and HIF-1α genes was found in the PDA-PHBV@5Gd-coated group. Soft tissue sealing (dpeaa)DE-He213 Poly(3-hydroxybutyrate-3-hydroxyvalerate) (PHBV) (dpeaa)DE-He213 Gd (dpeaa)DE-He213 Corrosion resistance (dpeaa)DE-He213 Human gingival fibroblasts (dpeaa)DE-He213 Xu, Xiongcheng aut Lu, Yanjin aut Li, Liu aut Huang, Tingting aut Lin, Jinxin aut Enthalten in Acta metallurgica Sinica Beijing : Springer, 1988 35(2021), 5 vom: 30. Juli, Seite 812-824 (DE-627)513220216 (DE-600)2238871-0 2194-1289 nnns volume:35 year:2021 number:5 day:30 month:07 pages:812-824 https://dx.doi.org/10.1007/s40195-021-01292-4 lizenzpflichtig Volltext GBV_USEFLAG_A SYSFLAG_A GBV_SPRINGER GBV_ILN_11 GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_32 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_70 GBV_ILN_73 GBV_ILN_74 GBV_ILN_90 GBV_ILN_95 GBV_ILN_100 GBV_ILN_105 GBV_ILN_110 GBV_ILN_120 GBV_ILN_121 GBV_ILN_138 GBV_ILN_150 GBV_ILN_151 GBV_ILN_152 GBV_ILN_161 GBV_ILN_170 GBV_ILN_171 GBV_ILN_187 GBV_ILN_206 GBV_ILN_213 GBV_ILN_224 GBV_ILN_230 GBV_ILN_250 GBV_ILN_281 GBV_ILN_285 GBV_ILN_293 GBV_ILN_370 GBV_ILN_374 GBV_ILN_602 GBV_ILN_636 GBV_ILN_647 GBV_ILN_702 GBV_ILN_2001 GBV_ILN_2003 GBV_ILN_2004 GBV_ILN_2005 GBV_ILN_2006 GBV_ILN_2007 GBV_ILN_2008 GBV_ILN_2009 GBV_ILN_2010 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2015 GBV_ILN_2018 GBV_ILN_2020 GBV_ILN_2021 GBV_ILN_2025 GBV_ILN_2026 GBV_ILN_2027 GBV_ILN_2031 GBV_ILN_2034 GBV_ILN_2036 GBV_ILN_2037 GBV_ILN_2038 GBV_ILN_2039 GBV_ILN_2044 GBV_ILN_2048 GBV_ILN_2049 GBV_ILN_2050 GBV_ILN_2055 GBV_ILN_2056 GBV_ILN_2057 GBV_ILN_2059 GBV_ILN_2061 GBV_ILN_2064 GBV_ILN_2065 GBV_ILN_2068 GBV_ILN_2088 GBV_ILN_2093 GBV_ILN_2106 GBV_ILN_2107 GBV_ILN_2108 GBV_ILN_2110 GBV_ILN_2111 GBV_ILN_2112 GBV_ILN_2113 GBV_ILN_2118 GBV_ILN_2119 GBV_ILN_2122 GBV_ILN_2129 GBV_ILN_2143 GBV_ILN_2144 GBV_ILN_2147 GBV_ILN_2148 GBV_ILN_2152 GBV_ILN_2153 GBV_ILN_2188 GBV_ILN_2190 GBV_ILN_2232 GBV_ILN_2336 GBV_ILN_2446 GBV_ILN_2470 GBV_ILN_2472 GBV_ILN_2507 GBV_ILN_2522 GBV_ILN_2548 GBV_ILN_2700 GBV_ILN_2817 GBV_ILN_4012 GBV_ILN_4035 GBV_ILN_4037 GBV_ILN_4046 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4242 GBV_ILN_4246 GBV_ILN_4249 GBV_ILN_4251 GBV_ILN_4277 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4326 GBV_ILN_4328 GBV_ILN_4333 GBV_ILN_4334 GBV_ILN_4335 GBV_ILN_4336 GBV_ILN_4338 GBV_ILN_4346 GBV_ILN_4367 GBV_ILN_4392 GBV_ILN_4393 GBV_ILN_4700 GBV_ILN_4753 AR 35 2021 5 30 07 812-824
allfields_unstemmed	10.1007/s40195-021-01292-4 doi (DE-627)SPR050611232 (SPR)s40195-021-01292-4-e DE-627 ger DE-627 rakwb eng Qin, Sijie verfasserin aut Doping Gd3+ Ion in PDA-PHBV Coating on Ti6Al4V Alloy for Enhancing Corrosion Resistance and Proliferation of Human Gingival Fibroblasts and Human Umbilical Vein Endothelial Cells 2021 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier © The Chinese Society for Metals (CSM) and Springer-Verlag GmbH Germany, part of Springer Nature 2021 Abstract In this study, we fabricated poly(3-hydroxybutyrate-3-hydroxyvalerate) (PHBV) coatings doped with $ Gd^{3+} $ (1, 5, and 10 × $ 10^{−4} $ mol/L) on Ti6Al4V alloy for the first time to promote soft tissue sealing around dental implants. The corrosion resistance of $ Gd^{3+} $-modified PHBV-coated Ti6Al4V was studied by electrochemical and immersion tests, respectively, whereas CCK-8 and RT-PCR evaluated the biocompatibility to human gingival fibroblasts (HGFs) and human umbilical vein endothelial cells (HUVECs). It was found that the $ Gd^{3+} $-modified PHBV coating could enhance the corrosion resistance of Ti6Al4V. In vitro cell tests showed that PHBV coatings with and without $ Gd^{3+} $ addition could promote adhesion and proliferation of HGFs and HUVECs, showing a $ Gd^{3+} $ content-dependent manner. Moreover, it was found that the PDA-PHBV1Gd showed the best proliferation to HGFs by up-regulating gene expressions of VINCULIN, ITGB1, and ITGA3, whereas the best response to HUVECs with the highest gene expression of eNOS and HIF-1α genes was found in the PDA-PHBV@5Gd-coated group. Soft tissue sealing (dpeaa)DE-He213 Poly(3-hydroxybutyrate-3-hydroxyvalerate) (PHBV) (dpeaa)DE-He213 Gd (dpeaa)DE-He213 Corrosion resistance (dpeaa)DE-He213 Human gingival fibroblasts (dpeaa)DE-He213 Xu, Xiongcheng aut Lu, Yanjin aut Li, Liu aut Huang, Tingting aut Lin, Jinxin aut Enthalten in Acta metallurgica Sinica Beijing : Springer, 1988 35(2021), 5 vom: 30. Juli, Seite 812-824 (DE-627)513220216 (DE-600)2238871-0 2194-1289 nnns volume:35 year:2021 number:5 day:30 month:07 pages:812-824 https://dx.doi.org/10.1007/s40195-021-01292-4 lizenzpflichtig Volltext GBV_USEFLAG_A SYSFLAG_A GBV_SPRINGER GBV_ILN_11 GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_32 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_70 GBV_ILN_73 GBV_ILN_74 GBV_ILN_90 GBV_ILN_95 GBV_ILN_100 GBV_ILN_105 GBV_ILN_110 GBV_ILN_120 GBV_ILN_121 GBV_ILN_138 GBV_ILN_150 GBV_ILN_151 GBV_ILN_152 GBV_ILN_161 GBV_ILN_170 GBV_ILN_171 GBV_ILN_187 GBV_ILN_206 GBV_ILN_213 GBV_ILN_224 GBV_ILN_230 GBV_ILN_250 GBV_ILN_281 GBV_ILN_285 GBV_ILN_293 GBV_ILN_370 GBV_ILN_374 GBV_ILN_602 GBV_ILN_636 GBV_ILN_647 GBV_ILN_702 GBV_ILN_2001 GBV_ILN_2003 GBV_ILN_2004 GBV_ILN_2005 GBV_ILN_2006 GBV_ILN_2007 GBV_ILN_2008 GBV_ILN_2009 GBV_ILN_2010 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2015 GBV_ILN_2018 GBV_ILN_2020 GBV_ILN_2021 GBV_ILN_2025 GBV_ILN_2026 GBV_ILN_2027 GBV_ILN_2031 GBV_ILN_2034 GBV_ILN_2036 GBV_ILN_2037 GBV_ILN_2038 GBV_ILN_2039 GBV_ILN_2044 GBV_ILN_2048 GBV_ILN_2049 GBV_ILN_2050 GBV_ILN_2055 GBV_ILN_2056 GBV_ILN_2057 GBV_ILN_2059 GBV_ILN_2061 GBV_ILN_2064 GBV_ILN_2065 GBV_ILN_2068 GBV_ILN_2088 GBV_ILN_2093 GBV_ILN_2106 GBV_ILN_2107 GBV_ILN_2108 GBV_ILN_2110 GBV_ILN_2111 GBV_ILN_2112 GBV_ILN_2113 GBV_ILN_2118 GBV_ILN_2119 GBV_ILN_2122 GBV_ILN_2129 GBV_ILN_2143 GBV_ILN_2144 GBV_ILN_2147 GBV_ILN_2148 GBV_ILN_2152 GBV_ILN_2153 GBV_ILN_2188 GBV_ILN_2190 GBV_ILN_2232 GBV_ILN_2336 GBV_ILN_2446 GBV_ILN_2470 GBV_ILN_2472 GBV_ILN_2507 GBV_ILN_2522 GBV_ILN_2548 GBV_ILN_2700 GBV_ILN_2817 GBV_ILN_4012 GBV_ILN_4035 GBV_ILN_4037 GBV_ILN_4046 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4242 GBV_ILN_4246 GBV_ILN_4249 GBV_ILN_4251 GBV_ILN_4277 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4326 GBV_ILN_4328 GBV_ILN_4333 GBV_ILN_4334 GBV_ILN_4335 GBV_ILN_4336 GBV_ILN_4338 GBV_ILN_4346 GBV_ILN_4367 GBV_ILN_4392 GBV_ILN_4393 GBV_ILN_4700 GBV_ILN_4753 AR 35 2021 5 30 07 812-824
allfieldsGer	10.1007/s40195-021-01292-4 doi (DE-627)SPR050611232 (SPR)s40195-021-01292-4-e DE-627 ger DE-627 rakwb eng Qin, Sijie verfasserin aut Doping Gd3+ Ion in PDA-PHBV Coating on Ti6Al4V Alloy for Enhancing Corrosion Resistance and Proliferation of Human Gingival Fibroblasts and Human Umbilical Vein Endothelial Cells 2021 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier © The Chinese Society for Metals (CSM) and Springer-Verlag GmbH Germany, part of Springer Nature 2021 Abstract In this study, we fabricated poly(3-hydroxybutyrate-3-hydroxyvalerate) (PHBV) coatings doped with $ Gd^{3+} $ (1, 5, and 10 × $ 10^{−4} $ mol/L) on Ti6Al4V alloy for the first time to promote soft tissue sealing around dental implants. The corrosion resistance of $ Gd^{3+} $-modified PHBV-coated Ti6Al4V was studied by electrochemical and immersion tests, respectively, whereas CCK-8 and RT-PCR evaluated the biocompatibility to human gingival fibroblasts (HGFs) and human umbilical vein endothelial cells (HUVECs). It was found that the $ Gd^{3+} $-modified PHBV coating could enhance the corrosion resistance of Ti6Al4V. In vitro cell tests showed that PHBV coatings with and without $ Gd^{3+} $ addition could promote adhesion and proliferation of HGFs and HUVECs, showing a $ Gd^{3+} $ content-dependent manner. Moreover, it was found that the PDA-PHBV1Gd showed the best proliferation to HGFs by up-regulating gene expressions of VINCULIN, ITGB1, and ITGA3, whereas the best response to HUVECs with the highest gene expression of eNOS and HIF-1α genes was found in the PDA-PHBV@5Gd-coated group. Soft tissue sealing (dpeaa)DE-He213 Poly(3-hydroxybutyrate-3-hydroxyvalerate) (PHBV) (dpeaa)DE-He213 Gd (dpeaa)DE-He213 Corrosion resistance (dpeaa)DE-He213 Human gingival fibroblasts (dpeaa)DE-He213 Xu, Xiongcheng aut Lu, Yanjin aut Li, Liu aut Huang, Tingting aut Lin, Jinxin aut Enthalten in Acta metallurgica Sinica Beijing : Springer, 1988 35(2021), 5 vom: 30. Juli, Seite 812-824 (DE-627)513220216 (DE-600)2238871-0 2194-1289 nnns volume:35 year:2021 number:5 day:30 month:07 pages:812-824 https://dx.doi.org/10.1007/s40195-021-01292-4 lizenzpflichtig Volltext GBV_USEFLAG_A SYSFLAG_A GBV_SPRINGER GBV_ILN_11 GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_32 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_70 GBV_ILN_73 GBV_ILN_74 GBV_ILN_90 GBV_ILN_95 GBV_ILN_100 GBV_ILN_105 GBV_ILN_110 GBV_ILN_120 GBV_ILN_121 GBV_ILN_138 GBV_ILN_150 GBV_ILN_151 GBV_ILN_152 GBV_ILN_161 GBV_ILN_170 GBV_ILN_171 GBV_ILN_187 GBV_ILN_206 GBV_ILN_213 GBV_ILN_224 GBV_ILN_230 GBV_ILN_250 GBV_ILN_281 GBV_ILN_285 GBV_ILN_293 GBV_ILN_370 GBV_ILN_374 GBV_ILN_602 GBV_ILN_636 GBV_ILN_647 GBV_ILN_702 GBV_ILN_2001 GBV_ILN_2003 GBV_ILN_2004 GBV_ILN_2005 GBV_ILN_2006 GBV_ILN_2007 GBV_ILN_2008 GBV_ILN_2009 GBV_ILN_2010 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2015 GBV_ILN_2018 GBV_ILN_2020 GBV_ILN_2021 GBV_ILN_2025 GBV_ILN_2026 GBV_ILN_2027 GBV_ILN_2031 GBV_ILN_2034 GBV_ILN_2036 GBV_ILN_2037 GBV_ILN_2038 GBV_ILN_2039 GBV_ILN_2044 GBV_ILN_2048 GBV_ILN_2049 GBV_ILN_2050 GBV_ILN_2055 GBV_ILN_2056 GBV_ILN_2057 GBV_ILN_2059 GBV_ILN_2061 GBV_ILN_2064 GBV_ILN_2065 GBV_ILN_2068 GBV_ILN_2088 GBV_ILN_2093 GBV_ILN_2106 GBV_ILN_2107 GBV_ILN_2108 GBV_ILN_2110 GBV_ILN_2111 GBV_ILN_2112 GBV_ILN_2113 GBV_ILN_2118 GBV_ILN_2119 GBV_ILN_2122 GBV_ILN_2129 GBV_ILN_2143 GBV_ILN_2144 GBV_ILN_2147 GBV_ILN_2148 GBV_ILN_2152 GBV_ILN_2153 GBV_ILN_2188 GBV_ILN_2190 GBV_ILN_2232 GBV_ILN_2336 GBV_ILN_2446 GBV_ILN_2470 GBV_ILN_2472 GBV_ILN_2507 GBV_ILN_2522 GBV_ILN_2548 GBV_ILN_2700 GBV_ILN_2817 GBV_ILN_4012 GBV_ILN_4035 GBV_ILN_4037 GBV_ILN_4046 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4242 GBV_ILN_4246 GBV_ILN_4249 GBV_ILN_4251 GBV_ILN_4277 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4326 GBV_ILN_4328 GBV_ILN_4333 GBV_ILN_4334 GBV_ILN_4335 GBV_ILN_4336 GBV_ILN_4338 GBV_ILN_4346 GBV_ILN_4367 GBV_ILN_4392 GBV_ILN_4393 GBV_ILN_4700 GBV_ILN_4753 AR 35 2021 5 30 07 812-824
allfieldsSound	10.1007/s40195-021-01292-4 doi (DE-627)SPR050611232 (SPR)s40195-021-01292-4-e DE-627 ger DE-627 rakwb eng Qin, Sijie verfasserin aut Doping Gd3+ Ion in PDA-PHBV Coating on Ti6Al4V Alloy for Enhancing Corrosion Resistance and Proliferation of Human Gingival Fibroblasts and Human Umbilical Vein Endothelial Cells 2021 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier © The Chinese Society for Metals (CSM) and Springer-Verlag GmbH Germany, part of Springer Nature 2021 Abstract In this study, we fabricated poly(3-hydroxybutyrate-3-hydroxyvalerate) (PHBV) coatings doped with $ Gd^{3+} $ (1, 5, and 10 × $ 10^{−4} $ mol/L) on Ti6Al4V alloy for the first time to promote soft tissue sealing around dental implants. The corrosion resistance of $ Gd^{3+} $-modified PHBV-coated Ti6Al4V was studied by electrochemical and immersion tests, respectively, whereas CCK-8 and RT-PCR evaluated the biocompatibility to human gingival fibroblasts (HGFs) and human umbilical vein endothelial cells (HUVECs). It was found that the $ Gd^{3+} $-modified PHBV coating could enhance the corrosion resistance of Ti6Al4V. In vitro cell tests showed that PHBV coatings with and without $ Gd^{3+} $ addition could promote adhesion and proliferation of HGFs and HUVECs, showing a $ Gd^{3+} $ content-dependent manner. Moreover, it was found that the PDA-PHBV1Gd showed the best proliferation to HGFs by up-regulating gene expressions of VINCULIN, ITGB1, and ITGA3, whereas the best response to HUVECs with the highest gene expression of eNOS and HIF-1α genes was found in the PDA-PHBV@5Gd-coated group. Soft tissue sealing (dpeaa)DE-He213 Poly(3-hydroxybutyrate-3-hydroxyvalerate) (PHBV) (dpeaa)DE-He213 Gd (dpeaa)DE-He213 Corrosion resistance (dpeaa)DE-He213 Human gingival fibroblasts (dpeaa)DE-He213 Xu, Xiongcheng aut Lu, Yanjin aut Li, Liu aut Huang, Tingting aut Lin, Jinxin aut Enthalten in Acta metallurgica Sinica Beijing : Springer, 1988 35(2021), 5 vom: 30. Juli, Seite 812-824 (DE-627)513220216 (DE-600)2238871-0 2194-1289 nnns volume:35 year:2021 number:5 day:30 month:07 pages:812-824 https://dx.doi.org/10.1007/s40195-021-01292-4 lizenzpflichtig Volltext GBV_USEFLAG_A SYSFLAG_A GBV_SPRINGER GBV_ILN_11 GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_32 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_70 GBV_ILN_73 GBV_ILN_74 GBV_ILN_90 GBV_ILN_95 GBV_ILN_100 GBV_ILN_105 GBV_ILN_110 GBV_ILN_120 GBV_ILN_121 GBV_ILN_138 GBV_ILN_150 GBV_ILN_151 GBV_ILN_152 GBV_ILN_161 GBV_ILN_170 GBV_ILN_171 GBV_ILN_187 GBV_ILN_206 GBV_ILN_213 GBV_ILN_224 GBV_ILN_230 GBV_ILN_250 GBV_ILN_281 GBV_ILN_285 GBV_ILN_293 GBV_ILN_370 GBV_ILN_374 GBV_ILN_602 GBV_ILN_636 GBV_ILN_647 GBV_ILN_702 GBV_ILN_2001 GBV_ILN_2003 GBV_ILN_2004 GBV_ILN_2005 GBV_ILN_2006 GBV_ILN_2007 GBV_ILN_2008 GBV_ILN_2009 GBV_ILN_2010 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2015 GBV_ILN_2018 GBV_ILN_2020 GBV_ILN_2021 GBV_ILN_2025 GBV_ILN_2026 GBV_ILN_2027 GBV_ILN_2031 GBV_ILN_2034 GBV_ILN_2036 GBV_ILN_2037 GBV_ILN_2038 GBV_ILN_2039 GBV_ILN_2044 GBV_ILN_2048 GBV_ILN_2049 GBV_ILN_2050 GBV_ILN_2055 GBV_ILN_2056 GBV_ILN_2057 GBV_ILN_2059 GBV_ILN_2061 GBV_ILN_2064 GBV_ILN_2065 GBV_ILN_2068 GBV_ILN_2088 GBV_ILN_2093 GBV_ILN_2106 GBV_ILN_2107 GBV_ILN_2108 GBV_ILN_2110 GBV_ILN_2111 GBV_ILN_2112 GBV_ILN_2113 GBV_ILN_2118 GBV_ILN_2119 GBV_ILN_2122 GBV_ILN_2129 GBV_ILN_2143 GBV_ILN_2144 GBV_ILN_2147 GBV_ILN_2148 GBV_ILN_2152 GBV_ILN_2153 GBV_ILN_2188 GBV_ILN_2190 GBV_ILN_2232 GBV_ILN_2336 GBV_ILN_2446 GBV_ILN_2470 GBV_ILN_2472 GBV_ILN_2507 GBV_ILN_2522 GBV_ILN_2548 GBV_ILN_2700 GBV_ILN_2817 GBV_ILN_4012 GBV_ILN_4035 GBV_ILN_4037 GBV_ILN_4046 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4242 GBV_ILN_4246 GBV_ILN_4249 GBV_ILN_4251 GBV_ILN_4277 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4326 GBV_ILN_4328 GBV_ILN_4333 GBV_ILN_4334 GBV_ILN_4335 GBV_ILN_4336 GBV_ILN_4338 GBV_ILN_4346 GBV_ILN_4367 GBV_ILN_4392 GBV_ILN_4393 GBV_ILN_4700 GBV_ILN_4753 AR 35 2021 5 30 07 812-824
language	English
source	Enthalten in Acta metallurgica Sinica 35(2021), 5 vom: 30. Juli, Seite 812-824 volume:35 year:2021 number:5 day:30 month:07 pages:812-824
sourceStr	Enthalten in Acta metallurgica Sinica 35(2021), 5 vom: 30. Juli, Seite 812-824 volume:35 year:2021 number:5 day:30 month:07 pages:812-824
format_phy_str_mv	Article
institution	findex.gbv.de
topic_facet	Soft tissue sealing Poly(3-hydroxybutyrate-3-hydroxyvalerate) (PHBV) Gd Corrosion resistance Human gingival fibroblasts
isfreeaccess_bool	false
container_title	Acta metallurgica Sinica
authorswithroles_txt_mv	Qin, Sijie @@aut@@ Xu, Xiongcheng @@aut@@ Lu, Yanjin @@aut@@ Li, Liu @@aut@@ Huang, Tingting @@aut@@ Lin, Jinxin @@aut@@
publishDateDaySort_date	2021-07-30T00:00:00Z
hierarchy_top_id	513220216
id	SPR050611232
language_de	englisch
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author	Qin, Sijie
spellingShingle	Qin, Sijie misc Soft tissue sealing misc Poly(3-hydroxybutyrate-3-hydroxyvalerate) (PHBV) misc Gd misc Corrosion resistance misc Human gingival fibroblasts Doping Gd3+ Ion in PDA-PHBV Coating on Ti6Al4V Alloy for Enhancing Corrosion Resistance and Proliferation of Human Gingival Fibroblasts and Human Umbilical Vein Endothelial Cells
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topic_title	Doping Gd3+ Ion in PDA-PHBV Coating on Ti6Al4V Alloy for Enhancing Corrosion Resistance and Proliferation of Human Gingival Fibroblasts and Human Umbilical Vein Endothelial Cells Soft tissue sealing (dpeaa)DE-He213 Poly(3-hydroxybutyrate-3-hydroxyvalerate) (PHBV) (dpeaa)DE-He213 Gd (dpeaa)DE-He213 Corrosion resistance (dpeaa)DE-He213 Human gingival fibroblasts (dpeaa)DE-He213
topic	misc Soft tissue sealing misc Poly(3-hydroxybutyrate-3-hydroxyvalerate) (PHBV) misc Gd misc Corrosion resistance misc Human gingival fibroblasts
topic_unstemmed	misc Soft tissue sealing misc Poly(3-hydroxybutyrate-3-hydroxyvalerate) (PHBV) misc Gd misc Corrosion resistance misc Human gingival fibroblasts
topic_browse	misc Soft tissue sealing misc Poly(3-hydroxybutyrate-3-hydroxyvalerate) (PHBV) misc Gd misc Corrosion resistance misc Human gingival fibroblasts
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title	Doping Gd3+ Ion in PDA-PHBV Coating on Ti6Al4V Alloy for Enhancing Corrosion Resistance and Proliferation of Human Gingival Fibroblasts and Human Umbilical Vein Endothelial Cells
ctrlnum	(DE-627)SPR050611232 (SPR)s40195-021-01292-4-e
title_full	Doping Gd3+ Ion in PDA-PHBV Coating on Ti6Al4V Alloy for Enhancing Corrosion Resistance and Proliferation of Human Gingival Fibroblasts and Human Umbilical Vein Endothelial Cells
author_sort	Qin, Sijie
journal	Acta metallurgica Sinica
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author_browse	Qin, Sijie Xu, Xiongcheng Lu, Yanjin Li, Liu Huang, Tingting Lin, Jinxin
container_volume	35
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author-letter	Qin, Sijie
doi_str_mv	10.1007/s40195-021-01292-4
title_sort	doping gd3+ ion in pda-phbv coating on ti6al4v alloy for enhancing corrosion resistance and proliferation of human gingival fibroblasts and human umbilical vein endothelial cells
title_auth	Doping Gd3+ Ion in PDA-PHBV Coating on Ti6Al4V Alloy for Enhancing Corrosion Resistance and Proliferation of Human Gingival Fibroblasts and Human Umbilical Vein Endothelial Cells
abstract	Abstract In this study, we fabricated poly(3-hydroxybutyrate-3-hydroxyvalerate) (PHBV) coatings doped with $ Gd^{3+} $ (1, 5, and 10 × $ 10^{−4} $ mol/L) on Ti6Al4V alloy for the first time to promote soft tissue sealing around dental implants. The corrosion resistance of $ Gd^{3+} $-modified PHBV-coated Ti6Al4V was studied by electrochemical and immersion tests, respectively, whereas CCK-8 and RT-PCR evaluated the biocompatibility to human gingival fibroblasts (HGFs) and human umbilical vein endothelial cells (HUVECs). It was found that the $ Gd^{3+} $-modified PHBV coating could enhance the corrosion resistance of Ti6Al4V. In vitro cell tests showed that PHBV coatings with and without $ Gd^{3+} $ addition could promote adhesion and proliferation of HGFs and HUVECs, showing a $ Gd^{3+} $ content-dependent manner. Moreover, it was found that the PDA-PHBV1Gd showed the best proliferation to HGFs by up-regulating gene expressions of VINCULIN, ITGB1, and ITGA3, whereas the best response to HUVECs with the highest gene expression of eNOS and HIF-1α genes was found in the PDA-PHBV@5Gd-coated group. © The Chinese Society for Metals (CSM) and Springer-Verlag GmbH Germany, part of Springer Nature 2021
abstractGer	Abstract In this study, we fabricated poly(3-hydroxybutyrate-3-hydroxyvalerate) (PHBV) coatings doped with $ Gd^{3+} $ (1, 5, and 10 × $ 10^{−4} $ mol/L) on Ti6Al4V alloy for the first time to promote soft tissue sealing around dental implants. The corrosion resistance of $ Gd^{3+} $-modified PHBV-coated Ti6Al4V was studied by electrochemical and immersion tests, respectively, whereas CCK-8 and RT-PCR evaluated the biocompatibility to human gingival fibroblasts (HGFs) and human umbilical vein endothelial cells (HUVECs). It was found that the $ Gd^{3+} $-modified PHBV coating could enhance the corrosion resistance of Ti6Al4V. In vitro cell tests showed that PHBV coatings with and without $ Gd^{3+} $ addition could promote adhesion and proliferation of HGFs and HUVECs, showing a $ Gd^{3+} $ content-dependent manner. Moreover, it was found that the PDA-PHBV1Gd showed the best proliferation to HGFs by up-regulating gene expressions of VINCULIN, ITGB1, and ITGA3, whereas the best response to HUVECs with the highest gene expression of eNOS and HIF-1α genes was found in the PDA-PHBV@5Gd-coated group. © The Chinese Society for Metals (CSM) and Springer-Verlag GmbH Germany, part of Springer Nature 2021
abstract_unstemmed	Abstract In this study, we fabricated poly(3-hydroxybutyrate-3-hydroxyvalerate) (PHBV) coatings doped with $ Gd^{3+} $ (1, 5, and 10 × $ 10^{−4} $ mol/L) on Ti6Al4V alloy for the first time to promote soft tissue sealing around dental implants. The corrosion resistance of $ Gd^{3+} $-modified PHBV-coated Ti6Al4V was studied by electrochemical and immersion tests, respectively, whereas CCK-8 and RT-PCR evaluated the biocompatibility to human gingival fibroblasts (HGFs) and human umbilical vein endothelial cells (HUVECs). It was found that the $ Gd^{3+} $-modified PHBV coating could enhance the corrosion resistance of Ti6Al4V. In vitro cell tests showed that PHBV coatings with and without $ Gd^{3+} $ addition could promote adhesion and proliferation of HGFs and HUVECs, showing a $ Gd^{3+} $ content-dependent manner. Moreover, it was found that the PDA-PHBV1Gd showed the best proliferation to HGFs by up-regulating gene expressions of VINCULIN, ITGB1, and ITGA3, whereas the best response to HUVECs with the highest gene expression of eNOS and HIF-1α genes was found in the PDA-PHBV@5Gd-coated group. © The Chinese Society for Metals (CSM) and Springer-Verlag GmbH Germany, part of Springer Nature 2021
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container_issue	5
title_short	Doping Gd3+ Ion in PDA-PHBV Coating on Ti6Al4V Alloy for Enhancing Corrosion Resistance and Proliferation of Human Gingival Fibroblasts and Human Umbilical Vein Endothelial Cells
url	https://dx.doi.org/10.1007/s40195-021-01292-4
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author2	Xu, Xiongcheng Lu, Yanjin Li, Liu Huang, Tingting Lin, Jinxin
author2Str	Xu, Xiongcheng Lu, Yanjin Li, Liu Huang, Tingting Lin, Jinxin
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doi_str	10.1007/s40195-021-01292-4
up_date	2024-07-03T16:39:03.070Z
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Doping Gd3+ Ion in PDA-PHBV Coating on Ti6Al4V Alloy for Enhancing Corrosion Resistance and Proliferation of Human Gingival Fibroblasts and Human Umbilical Vein Endothelial Cells

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