Ultra-wide field imaging to assess the optic nerve and retina in Boston type I and II keratoprosthesis patients

Background The ability to view the posterior segment in keratoprosthesis (Kpro) implanted patients is limited. The purpose of this retrospective, observational study was to investigate the use of ultra-wide field (UWF) scanning laser ophthalmoscopy imaging and its utility for serial evaluation of th...
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Autor*in:	Bloom, William R. [verfasserIn] Karl, Matthew D. Smith, Sarah B. Shao, Yusra F. Terrell, William Tarabishy, Ahmad B. Hendershot, Andrew J. Kuennen, Rebecca A. Oostra, Tyler D. Mauger, Thomas F. Cebulla, Colleen M.

Format:	E-Artikel
Sprache:	Englisch

Erschienen:	2022

Schlagwörter:	Corneal diseases Diagnostic eye imaging Posterior eye segment Prosthesis implantation

Anmerkung:	© The Author(s) 2022

Übergeordnetes Werk:	Enthalten in: Eye and Vision - London : BioMed Central, 2014, 9(2022), 1 vom: 07. Mai
Übergeordnetes Werk:	volume:9 ; year:2022 ; number:1 ; day:07 ; month:05

Links:	Volltext

DOI / URN:	10.1186/s40662-022-00289-z

Katalog-ID:	SPR05069426X

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520			\|a Background The ability to view the posterior segment in keratoprosthesis (Kpro) implanted patients is limited. The purpose of this retrospective, observational study was to investigate the use of ultra-wide field (UWF) scanning laser ophthalmoscopy imaging and its utility for serial evaluation of the retina and optic nerve in patients with either a Boston type I or II Kpro. Methods A retrospective chart review was performed for patients with a Boston type I or II Kpro seen at The Ohio State University Wexner Medical Center. Images were graded for quality by two masked observers on a defined four-point scale (“Poor”, “Fair”, “Good”, or “Very good”) and assessed for visible posterior segment anatomy. Interobserver agreement was described using the Kappa statistic coefficient (κ) with 95% confidence intervals. Results A total of 19 eyes from 17 patients were included in this study. Eighteen eyes had a type I Kpro, while one eye had a type II Kpro. UWF imaging from 41 patient visits were reviewed by two observers. Interobserver agreement between the two graders was fair for image quality (κ = 0.36), moderate for visibility of the macula with discernible details (κ = 0.59), moderate for visibility of the anterior retina with discernable details (κ = 0.60), and perfect agreement for visibility of the optic nerve with discernible details (κ = 1.0). In 6 eyes, UWF imaging was performed longitudinally (range 3–9 individual visits), allowing for long-term follow-up (range 3–46 months) of posterior segment clinical pathology. Conclusions UWF imaging provides adequate and reliable visualization of the posterior segment in Kpro implanted patients. This imaging modality allowed for noninvasive longitudinal monitoring of retinal and optic nerve disease in this selected patient population.
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allfields	10.1186/s40662-022-00289-z doi (DE-627)SPR05069426X (SPR)s40662-022-00289-z-e DE-627 ger DE-627 rakwb eng Bloom, William R. verfasserin aut Ultra-wide field imaging to assess the optic nerve and retina in Boston type I and II keratoprosthesis patients 2022 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier © The Author(s) 2022 Background The ability to view the posterior segment in keratoprosthesis (Kpro) implanted patients is limited. The purpose of this retrospective, observational study was to investigate the use of ultra-wide field (UWF) scanning laser ophthalmoscopy imaging and its utility for serial evaluation of the retina and optic nerve in patients with either a Boston type I or II Kpro. Methods A retrospective chart review was performed for patients with a Boston type I or II Kpro seen at The Ohio State University Wexner Medical Center. Images were graded for quality by two masked observers on a defined four-point scale (“Poor”, “Fair”, “Good”, or “Very good”) and assessed for visible posterior segment anatomy. Interobserver agreement was described using the Kappa statistic coefficient (κ) with 95% confidence intervals. Results A total of 19 eyes from 17 patients were included in this study. Eighteen eyes had a type I Kpro, while one eye had a type II Kpro. UWF imaging from 41 patient visits were reviewed by two observers. Interobserver agreement between the two graders was fair for image quality (κ = 0.36), moderate for visibility of the macula with discernible details (κ = 0.59), moderate for visibility of the anterior retina with discernable details (κ = 0.60), and perfect agreement for visibility of the optic nerve with discernible details (κ = 1.0). In 6 eyes, UWF imaging was performed longitudinally (range 3–9 individual visits), allowing for long-term follow-up (range 3–46 months) of posterior segment clinical pathology. Conclusions UWF imaging provides adequate and reliable visualization of the posterior segment in Kpro implanted patients. This imaging modality allowed for noninvasive longitudinal monitoring of retinal and optic nerve disease in this selected patient population. Corneal diseases (dpeaa)DE-He213 Diagnostic eye imaging (dpeaa)DE-He213 Posterior eye segment (dpeaa)DE-He213 Prosthesis implantation (dpeaa)DE-He213 Karl, Matthew D. aut Smith, Sarah B. aut Shao, Yusra F. aut Terrell, William aut Tarabishy, Ahmad B. aut Hendershot, Andrew J. aut Kuennen, Rebecca A. aut Oostra, Tyler D. aut Mauger, Thomas F. aut Cebulla, Colleen M. (orcid)0000-0002-5636-4968 aut Enthalten in Eye and Vision London : BioMed Central, 2014 9(2022), 1 vom: 07. Mai (DE-627)815914113 (DE-600)2806610-8 2326-0254 nnns volume:9 year:2022 number:1 day:07 month:05 https://dx.doi.org/10.1186/s40662-022-00289-z kostenfrei Volltext GBV_USEFLAG_A SYSFLAG_A GBV_SPRINGER GBV_ILN_11 GBV_ILN_20 GBV_ILN_22 GBV_ILN_24 GBV_ILN_39 GBV_ILN_40 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_2003 GBV_ILN_2014 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 9 2022 1 07 05
spelling	10.1186/s40662-022-00289-z doi (DE-627)SPR05069426X (SPR)s40662-022-00289-z-e DE-627 ger DE-627 rakwb eng Bloom, William R. verfasserin aut Ultra-wide field imaging to assess the optic nerve and retina in Boston type I and II keratoprosthesis patients 2022 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier © The Author(s) 2022 Background The ability to view the posterior segment in keratoprosthesis (Kpro) implanted patients is limited. The purpose of this retrospective, observational study was to investigate the use of ultra-wide field (UWF) scanning laser ophthalmoscopy imaging and its utility for serial evaluation of the retina and optic nerve in patients with either a Boston type I or II Kpro. Methods A retrospective chart review was performed for patients with a Boston type I or II Kpro seen at The Ohio State University Wexner Medical Center. Images were graded for quality by two masked observers on a defined four-point scale (“Poor”, “Fair”, “Good”, or “Very good”) and assessed for visible posterior segment anatomy. Interobserver agreement was described using the Kappa statistic coefficient (κ) with 95% confidence intervals. Results A total of 19 eyes from 17 patients were included in this study. Eighteen eyes had a type I Kpro, while one eye had a type II Kpro. UWF imaging from 41 patient visits were reviewed by two observers. Interobserver agreement between the two graders was fair for image quality (κ = 0.36), moderate for visibility of the macula with discernible details (κ = 0.59), moderate for visibility of the anterior retina with discernable details (κ = 0.60), and perfect agreement for visibility of the optic nerve with discernible details (κ = 1.0). In 6 eyes, UWF imaging was performed longitudinally (range 3–9 individual visits), allowing for long-term follow-up (range 3–46 months) of posterior segment clinical pathology. Conclusions UWF imaging provides adequate and reliable visualization of the posterior segment in Kpro implanted patients. This imaging modality allowed for noninvasive longitudinal monitoring of retinal and optic nerve disease in this selected patient population. Corneal diseases (dpeaa)DE-He213 Diagnostic eye imaging (dpeaa)DE-He213 Posterior eye segment (dpeaa)DE-He213 Prosthesis implantation (dpeaa)DE-He213 Karl, Matthew D. aut Smith, Sarah B. aut Shao, Yusra F. aut Terrell, William aut Tarabishy, Ahmad B. aut Hendershot, Andrew J. aut Kuennen, Rebecca A. aut Oostra, Tyler D. aut Mauger, Thomas F. aut Cebulla, Colleen M. (orcid)0000-0002-5636-4968 aut Enthalten in Eye and Vision London : BioMed Central, 2014 9(2022), 1 vom: 07. Mai (DE-627)815914113 (DE-600)2806610-8 2326-0254 nnns volume:9 year:2022 number:1 day:07 month:05 https://dx.doi.org/10.1186/s40662-022-00289-z kostenfrei Volltext GBV_USEFLAG_A SYSFLAG_A GBV_SPRINGER GBV_ILN_11 GBV_ILN_20 GBV_ILN_22 GBV_ILN_24 GBV_ILN_39 GBV_ILN_40 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_2003 GBV_ILN_2014 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 9 2022 1 07 05
allfields_unstemmed	10.1186/s40662-022-00289-z doi (DE-627)SPR05069426X (SPR)s40662-022-00289-z-e DE-627 ger DE-627 rakwb eng Bloom, William R. verfasserin aut Ultra-wide field imaging to assess the optic nerve and retina in Boston type I and II keratoprosthesis patients 2022 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier © The Author(s) 2022 Background The ability to view the posterior segment in keratoprosthesis (Kpro) implanted patients is limited. The purpose of this retrospective, observational study was to investigate the use of ultra-wide field (UWF) scanning laser ophthalmoscopy imaging and its utility for serial evaluation of the retina and optic nerve in patients with either a Boston type I or II Kpro. Methods A retrospective chart review was performed for patients with a Boston type I or II Kpro seen at The Ohio State University Wexner Medical Center. Images were graded for quality by two masked observers on a defined four-point scale (“Poor”, “Fair”, “Good”, or “Very good”) and assessed for visible posterior segment anatomy. Interobserver agreement was described using the Kappa statistic coefficient (κ) with 95% confidence intervals. Results A total of 19 eyes from 17 patients were included in this study. Eighteen eyes had a type I Kpro, while one eye had a type II Kpro. UWF imaging from 41 patient visits were reviewed by two observers. Interobserver agreement between the two graders was fair for image quality (κ = 0.36), moderate for visibility of the macula with discernible details (κ = 0.59), moderate for visibility of the anterior retina with discernable details (κ = 0.60), and perfect agreement for visibility of the optic nerve with discernible details (κ = 1.0). In 6 eyes, UWF imaging was performed longitudinally (range 3–9 individual visits), allowing for long-term follow-up (range 3–46 months) of posterior segment clinical pathology. Conclusions UWF imaging provides adequate and reliable visualization of the posterior segment in Kpro implanted patients. This imaging modality allowed for noninvasive longitudinal monitoring of retinal and optic nerve disease in this selected patient population. Corneal diseases (dpeaa)DE-He213 Diagnostic eye imaging (dpeaa)DE-He213 Posterior eye segment (dpeaa)DE-He213 Prosthesis implantation (dpeaa)DE-He213 Karl, Matthew D. aut Smith, Sarah B. aut Shao, Yusra F. aut Terrell, William aut Tarabishy, Ahmad B. aut Hendershot, Andrew J. aut Kuennen, Rebecca A. aut Oostra, Tyler D. aut Mauger, Thomas F. aut Cebulla, Colleen M. (orcid)0000-0002-5636-4968 aut Enthalten in Eye and Vision London : BioMed Central, 2014 9(2022), 1 vom: 07. Mai (DE-627)815914113 (DE-600)2806610-8 2326-0254 nnns volume:9 year:2022 number:1 day:07 month:05 https://dx.doi.org/10.1186/s40662-022-00289-z kostenfrei Volltext GBV_USEFLAG_A SYSFLAG_A GBV_SPRINGER GBV_ILN_11 GBV_ILN_20 GBV_ILN_22 GBV_ILN_24 GBV_ILN_39 GBV_ILN_40 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_2003 GBV_ILN_2014 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 9 2022 1 07 05
allfieldsGer	10.1186/s40662-022-00289-z doi (DE-627)SPR05069426X (SPR)s40662-022-00289-z-e DE-627 ger DE-627 rakwb eng Bloom, William R. verfasserin aut Ultra-wide field imaging to assess the optic nerve and retina in Boston type I and II keratoprosthesis patients 2022 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier © The Author(s) 2022 Background The ability to view the posterior segment in keratoprosthesis (Kpro) implanted patients is limited. The purpose of this retrospective, observational study was to investigate the use of ultra-wide field (UWF) scanning laser ophthalmoscopy imaging and its utility for serial evaluation of the retina and optic nerve in patients with either a Boston type I or II Kpro. Methods A retrospective chart review was performed for patients with a Boston type I or II Kpro seen at The Ohio State University Wexner Medical Center. Images were graded for quality by two masked observers on a defined four-point scale (“Poor”, “Fair”, “Good”, or “Very good”) and assessed for visible posterior segment anatomy. Interobserver agreement was described using the Kappa statistic coefficient (κ) with 95% confidence intervals. Results A total of 19 eyes from 17 patients were included in this study. Eighteen eyes had a type I Kpro, while one eye had a type II Kpro. UWF imaging from 41 patient visits were reviewed by two observers. Interobserver agreement between the two graders was fair for image quality (κ = 0.36), moderate for visibility of the macula with discernible details (κ = 0.59), moderate for visibility of the anterior retina with discernable details (κ = 0.60), and perfect agreement for visibility of the optic nerve with discernible details (κ = 1.0). In 6 eyes, UWF imaging was performed longitudinally (range 3–9 individual visits), allowing for long-term follow-up (range 3–46 months) of posterior segment clinical pathology. Conclusions UWF imaging provides adequate and reliable visualization of the posterior segment in Kpro implanted patients. This imaging modality allowed for noninvasive longitudinal monitoring of retinal and optic nerve disease in this selected patient population. Corneal diseases (dpeaa)DE-He213 Diagnostic eye imaging (dpeaa)DE-He213 Posterior eye segment (dpeaa)DE-He213 Prosthesis implantation (dpeaa)DE-He213 Karl, Matthew D. aut Smith, Sarah B. aut Shao, Yusra F. aut Terrell, William aut Tarabishy, Ahmad B. aut Hendershot, Andrew J. aut Kuennen, Rebecca A. aut Oostra, Tyler D. aut Mauger, Thomas F. aut Cebulla, Colleen M. (orcid)0000-0002-5636-4968 aut Enthalten in Eye and Vision London : BioMed Central, 2014 9(2022), 1 vom: 07. Mai (DE-627)815914113 (DE-600)2806610-8 2326-0254 nnns volume:9 year:2022 number:1 day:07 month:05 https://dx.doi.org/10.1186/s40662-022-00289-z kostenfrei Volltext GBV_USEFLAG_A SYSFLAG_A GBV_SPRINGER GBV_ILN_11 GBV_ILN_20 GBV_ILN_22 GBV_ILN_24 GBV_ILN_39 GBV_ILN_40 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_2003 GBV_ILN_2014 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 9 2022 1 07 05
allfieldsSound	10.1186/s40662-022-00289-z doi (DE-627)SPR05069426X (SPR)s40662-022-00289-z-e DE-627 ger DE-627 rakwb eng Bloom, William R. verfasserin aut Ultra-wide field imaging to assess the optic nerve and retina in Boston type I and II keratoprosthesis patients 2022 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier © The Author(s) 2022 Background The ability to view the posterior segment in keratoprosthesis (Kpro) implanted patients is limited. The purpose of this retrospective, observational study was to investigate the use of ultra-wide field (UWF) scanning laser ophthalmoscopy imaging and its utility for serial evaluation of the retina and optic nerve in patients with either a Boston type I or II Kpro. Methods A retrospective chart review was performed for patients with a Boston type I or II Kpro seen at The Ohio State University Wexner Medical Center. Images were graded for quality by two masked observers on a defined four-point scale (“Poor”, “Fair”, “Good”, or “Very good”) and assessed for visible posterior segment anatomy. Interobserver agreement was described using the Kappa statistic coefficient (κ) with 95% confidence intervals. Results A total of 19 eyes from 17 patients were included in this study. Eighteen eyes had a type I Kpro, while one eye had a type II Kpro. UWF imaging from 41 patient visits were reviewed by two observers. Interobserver agreement between the two graders was fair for image quality (κ = 0.36), moderate for visibility of the macula with discernible details (κ = 0.59), moderate for visibility of the anterior retina with discernable details (κ = 0.60), and perfect agreement for visibility of the optic nerve with discernible details (κ = 1.0). In 6 eyes, UWF imaging was performed longitudinally (range 3–9 individual visits), allowing for long-term follow-up (range 3–46 months) of posterior segment clinical pathology. Conclusions UWF imaging provides adequate and reliable visualization of the posterior segment in Kpro implanted patients. This imaging modality allowed for noninvasive longitudinal monitoring of retinal and optic nerve disease in this selected patient population. Corneal diseases (dpeaa)DE-He213 Diagnostic eye imaging (dpeaa)DE-He213 Posterior eye segment (dpeaa)DE-He213 Prosthesis implantation (dpeaa)DE-He213 Karl, Matthew D. aut Smith, Sarah B. aut Shao, Yusra F. aut Terrell, William aut Tarabishy, Ahmad B. aut Hendershot, Andrew J. aut Kuennen, Rebecca A. aut Oostra, Tyler D. aut Mauger, Thomas F. aut Cebulla, Colleen M. (orcid)0000-0002-5636-4968 aut Enthalten in Eye and Vision London : BioMed Central, 2014 9(2022), 1 vom: 07. Mai (DE-627)815914113 (DE-600)2806610-8 2326-0254 nnns volume:9 year:2022 number:1 day:07 month:05 https://dx.doi.org/10.1186/s40662-022-00289-z kostenfrei Volltext GBV_USEFLAG_A SYSFLAG_A GBV_SPRINGER GBV_ILN_11 GBV_ILN_20 GBV_ILN_22 GBV_ILN_24 GBV_ILN_39 GBV_ILN_40 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_2003 GBV_ILN_2014 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 9 2022 1 07 05
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source	Enthalten in Eye and Vision 9(2022), 1 vom: 07. Mai volume:9 year:2022 number:1 day:07 month:05
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topic_facet	Corneal diseases Diagnostic eye imaging Posterior eye segment Prosthesis implantation
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authorswithroles_txt_mv	Bloom, William R. @@aut@@ Karl, Matthew D. @@aut@@ Smith, Sarah B. @@aut@@ Shao, Yusra F. @@aut@@ Terrell, William @@aut@@ Tarabishy, Ahmad B. @@aut@@ Hendershot, Andrew J. @@aut@@ Kuennen, Rebecca A. @@aut@@ Oostra, Tyler D. @@aut@@ Mauger, Thomas F. @@aut@@ Cebulla, Colleen M. @@aut@@
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The purpose of this retrospective, observational study was to investigate the use of ultra-wide field (UWF) scanning laser ophthalmoscopy imaging and its utility for serial evaluation of the retina and optic nerve in patients with either a Boston type I or II Kpro. Methods A retrospective chart review was performed for patients with a Boston type I or II Kpro seen at The Ohio State University Wexner Medical Center. Images were graded for quality by two masked observers on a defined four-point scale (“Poor”, “Fair”, “Good”, or “Very good”) and assessed for visible posterior segment anatomy. Interobserver agreement was described using the Kappa statistic coefficient (κ) with 95% confidence intervals. Results A total of 19 eyes from 17 patients were included in this study. Eighteen eyes had a type I Kpro, while one eye had a type II Kpro. UWF imaging from 41 patient visits were reviewed by two observers. Interobserver agreement between the two graders was fair for image quality (κ = 0.36), moderate for visibility of the macula with discernible details (κ = 0.59), moderate for visibility of the anterior retina with discernable details (κ = 0.60), and perfect agreement for visibility of the optic nerve with discernible details (κ = 1.0). In 6 eyes, UWF imaging was performed longitudinally (range 3–9 individual visits), allowing for long-term follow-up (range 3–46 months) of posterior segment clinical pathology. Conclusions UWF imaging provides adequate and reliable visualization of the posterior segment in Kpro implanted patients. 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author	Bloom, William R.
spellingShingle	Bloom, William R. misc Corneal diseases misc Diagnostic eye imaging misc Posterior eye segment misc Prosthesis implantation Ultra-wide field imaging to assess the optic nerve and retina in Boston type I and II keratoprosthesis patients
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topic_title	Ultra-wide field imaging to assess the optic nerve and retina in Boston type I and II keratoprosthesis patients Corneal diseases (dpeaa)DE-He213 Diagnostic eye imaging (dpeaa)DE-He213 Posterior eye segment (dpeaa)DE-He213 Prosthesis implantation (dpeaa)DE-He213
topic	misc Corneal diseases misc Diagnostic eye imaging misc Posterior eye segment misc Prosthesis implantation
topic_unstemmed	misc Corneal diseases misc Diagnostic eye imaging misc Posterior eye segment misc Prosthesis implantation
topic_browse	misc Corneal diseases misc Diagnostic eye imaging misc Posterior eye segment misc Prosthesis implantation
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title	Ultra-wide field imaging to assess the optic nerve and retina in Boston type I and II keratoprosthesis patients
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title_full	Ultra-wide field imaging to assess the optic nerve and retina in Boston type I and II keratoprosthesis patients
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author_browse	Bloom, William R. Karl, Matthew D. Smith, Sarah B. Shao, Yusra F. Terrell, William Tarabishy, Ahmad B. Hendershot, Andrew J. Kuennen, Rebecca A. Oostra, Tyler D. Mauger, Thomas F. Cebulla, Colleen M.
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title_sort	ultra-wide field imaging to assess the optic nerve and retina in boston type i and ii keratoprosthesis patients
title_auth	Ultra-wide field imaging to assess the optic nerve and retina in Boston type I and II keratoprosthesis patients
abstract	Background The ability to view the posterior segment in keratoprosthesis (Kpro) implanted patients is limited. The purpose of this retrospective, observational study was to investigate the use of ultra-wide field (UWF) scanning laser ophthalmoscopy imaging and its utility for serial evaluation of the retina and optic nerve in patients with either a Boston type I or II Kpro. Methods A retrospective chart review was performed for patients with a Boston type I or II Kpro seen at The Ohio State University Wexner Medical Center. Images were graded for quality by two masked observers on a defined four-point scale (“Poor”, “Fair”, “Good”, or “Very good”) and assessed for visible posterior segment anatomy. Interobserver agreement was described using the Kappa statistic coefficient (κ) with 95% confidence intervals. Results A total of 19 eyes from 17 patients were included in this study. Eighteen eyes had a type I Kpro, while one eye had a type II Kpro. UWF imaging from 41 patient visits were reviewed by two observers. Interobserver agreement between the two graders was fair for image quality (κ = 0.36), moderate for visibility of the macula with discernible details (κ = 0.59), moderate for visibility of the anterior retina with discernable details (κ = 0.60), and perfect agreement for visibility of the optic nerve with discernible details (κ = 1.0). In 6 eyes, UWF imaging was performed longitudinally (range 3–9 individual visits), allowing for long-term follow-up (range 3–46 months) of posterior segment clinical pathology. Conclusions UWF imaging provides adequate and reliable visualization of the posterior segment in Kpro implanted patients. This imaging modality allowed for noninvasive longitudinal monitoring of retinal and optic nerve disease in this selected patient population. © The Author(s) 2022
abstractGer	Background The ability to view the posterior segment in keratoprosthesis (Kpro) implanted patients is limited. The purpose of this retrospective, observational study was to investigate the use of ultra-wide field (UWF) scanning laser ophthalmoscopy imaging and its utility for serial evaluation of the retina and optic nerve in patients with either a Boston type I or II Kpro. Methods A retrospective chart review was performed for patients with a Boston type I or II Kpro seen at The Ohio State University Wexner Medical Center. Images were graded for quality by two masked observers on a defined four-point scale (“Poor”, “Fair”, “Good”, or “Very good”) and assessed for visible posterior segment anatomy. Interobserver agreement was described using the Kappa statistic coefficient (κ) with 95% confidence intervals. Results A total of 19 eyes from 17 patients were included in this study. Eighteen eyes had a type I Kpro, while one eye had a type II Kpro. UWF imaging from 41 patient visits were reviewed by two observers. Interobserver agreement between the two graders was fair for image quality (κ = 0.36), moderate for visibility of the macula with discernible details (κ = 0.59), moderate for visibility of the anterior retina with discernable details (κ = 0.60), and perfect agreement for visibility of the optic nerve with discernible details (κ = 1.0). In 6 eyes, UWF imaging was performed longitudinally (range 3–9 individual visits), allowing for long-term follow-up (range 3–46 months) of posterior segment clinical pathology. Conclusions UWF imaging provides adequate and reliable visualization of the posterior segment in Kpro implanted patients. This imaging modality allowed for noninvasive longitudinal monitoring of retinal and optic nerve disease in this selected patient population. © The Author(s) 2022
abstract_unstemmed	Background The ability to view the posterior segment in keratoprosthesis (Kpro) implanted patients is limited. The purpose of this retrospective, observational study was to investigate the use of ultra-wide field (UWF) scanning laser ophthalmoscopy imaging and its utility for serial evaluation of the retina and optic nerve in patients with either a Boston type I or II Kpro. Methods A retrospective chart review was performed for patients with a Boston type I or II Kpro seen at The Ohio State University Wexner Medical Center. Images were graded for quality by two masked observers on a defined four-point scale (“Poor”, “Fair”, “Good”, or “Very good”) and assessed for visible posterior segment anatomy. Interobserver agreement was described using the Kappa statistic coefficient (κ) with 95% confidence intervals. Results A total of 19 eyes from 17 patients were included in this study. Eighteen eyes had a type I Kpro, while one eye had a type II Kpro. UWF imaging from 41 patient visits were reviewed by two observers. Interobserver agreement between the two graders was fair for image quality (κ = 0.36), moderate for visibility of the macula with discernible details (κ = 0.59), moderate for visibility of the anterior retina with discernable details (κ = 0.60), and perfect agreement for visibility of the optic nerve with discernible details (κ = 1.0). In 6 eyes, UWF imaging was performed longitudinally (range 3–9 individual visits), allowing for long-term follow-up (range 3–46 months) of posterior segment clinical pathology. Conclusions UWF imaging provides adequate and reliable visualization of the posterior segment in Kpro implanted patients. This imaging modality allowed for noninvasive longitudinal monitoring of retinal and optic nerve disease in this selected patient population. © The Author(s) 2022
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title_short	Ultra-wide field imaging to assess the optic nerve and retina in Boston type I and II keratoprosthesis patients
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author2	Karl, Matthew D. Smith, Sarah B. Shao, Yusra F. Terrell, William Tarabishy, Ahmad B. Hendershot, Andrew J. Kuennen, Rebecca A. Oostra, Tyler D. Mauger, Thomas F. Cebulla, Colleen M.
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The purpose of this retrospective, observational study was to investigate the use of ultra-wide field (UWF) scanning laser ophthalmoscopy imaging and its utility for serial evaluation of the retina and optic nerve in patients with either a Boston type I or II Kpro. Methods A retrospective chart review was performed for patients with a Boston type I or II Kpro seen at The Ohio State University Wexner Medical Center. Images were graded for quality by two masked observers on a defined four-point scale (“Poor”, “Fair”, “Good”, or “Very good”) and assessed for visible posterior segment anatomy. Interobserver agreement was described using the Kappa statistic coefficient (κ) with 95% confidence intervals. Results A total of 19 eyes from 17 patients were included in this study. Eighteen eyes had a type I Kpro, while one eye had a type II Kpro. UWF imaging from 41 patient visits were reviewed by two observers. Interobserver agreement between the two graders was fair for image quality (κ = 0.36), moderate for visibility of the macula with discernible details (κ = 0.59), moderate for visibility of the anterior retina with discernable details (κ = 0.60), and perfect agreement for visibility of the optic nerve with discernible details (κ = 1.0). In 6 eyes, UWF imaging was performed longitudinally (range 3–9 individual visits), allowing for long-term follow-up (range 3–46 months) of posterior segment clinical pathology. Conclusions UWF imaging provides adequate and reliable visualization of the posterior segment in Kpro implanted patients. 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Ultra-wide field imaging to assess the optic nerve and retina in Boston type I and II keratoprosthesis patients

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