Soft robotic exosuit augmented high intensity gait training on stroke survivors: a pilot study

Background Stroke is a leading cause of serious gait impairments and restoring walking ability is a major goal of physical therapy interventions. Soft robotic exosuits are portable, lightweight, and unobtrusive assistive devices designed to improve the mobility of post-stroke individuals through fac...
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Autor*in:	Shin, Sung Yul [verfasserIn] Hohl, Kristen Giffhorn, Matt Awad, Louis N. Walsh, Conor J. Jayaraman, Arun

Format:	E-Artikel
Sprache:	Englisch

Erschienen:	2022

Schlagwörter:	Exosuit Soft robotics High intensity gait training Clinical outcomes Gait quality Stroke

Anmerkung:	© The Author(s) 2022. corrected publication 2022

Übergeordnetes Werk:	Enthalten in: Journal of neuroEngineering and rehabilitation - London : BioMed Central, 2004, 19(2022), 1 vom: 03. Juni
Übergeordnetes Werk:	volume:19 ; year:2022 ; number:1 ; day:03 ; month:06

Links:	Volltext

DOI / URN:	10.1186/s12984-022-01034-2

Katalog-ID:	SPR050754076

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allfields	10.1186/s12984-022-01034-2 doi (DE-627)SPR050754076 (SPR)s12984-022-01034-2-e DE-627 ger DE-627 rakwb eng Shin, Sung Yul verfasserin aut Soft robotic exosuit augmented high intensity gait training on stroke survivors: a pilot study 2022 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier © The Author(s) 2022. corrected publication 2022 Background Stroke is a leading cause of serious gait impairments and restoring walking ability is a major goal of physical therapy interventions. Soft robotic exosuits are portable, lightweight, and unobtrusive assistive devices designed to improve the mobility of post-stroke individuals through facilitation of more natural paretic limb function during walking training. However, it is unknown whether long-term gait training using soft robotic exosuits will clinically impact gait function and quality of movement post-stroke. Objective The objective of this pilot study was to examine the therapeutic effects of soft robotic exosuit-augmented gait training on clinical and biomechanical gait outcomes in chronic post-stroke individuals. Methods Five post-stroke individuals received high intensity gait training augmented with a soft robotic exosuit, delivered in 18 sessions over 6–8 weeks. Performance based clinical outcomes and biomechanical gait quality parameters were measured at baseline, midpoint, and completion. Results Clinically meaningful improvements were observed in walking speed (%$p%$ < 0.05) and endurance (%$p%$ < 0.01) together with other traditional gait related outcomes. The gait quality measures including hip (%$p%$ < 0.01) and knee (%$p%$ < 0.05) flexion/extension exhibited an increase in range of motion in a symmetric manner (%$p%$ < 0.05). We also observed an increase in bilateral ankle angular velocities (%$p%$ < 0.05), suggesting biomechanical improvements in walking function. Conclusions The results in this study offer preliminary evidence that a soft robotic exosuit can be a useful tool to augment high intensity gait training in a clinical setting. This study justifies more expanded research on soft exosuit technology with a larger post-stroke population for more reliable generalization. Trial registration This study is registered with ClinicalTrials.gov (ID: NCT04251091) Exosuit (dpeaa)DE-He213 Soft robotics (dpeaa)DE-He213 High intensity gait training (dpeaa)DE-He213 Clinical outcomes (dpeaa)DE-He213 Gait quality (dpeaa)DE-He213 Stroke (dpeaa)DE-He213 Hohl, Kristen aut Giffhorn, Matt aut Awad, Louis N. aut Walsh, Conor J. aut Jayaraman, Arun aut Enthalten in Journal of neuroEngineering and rehabilitation London : BioMed Central, 2004 19(2022), 1 vom: 03. Juni (DE-627)461907933 (DE-600)2164377-5 1743-0003 nnns volume:19 year:2022 number:1 day:03 month:06 https://dx.doi.org/10.1186/s12984-022-01034-2 kostenfrei Volltext GBV_USEFLAG_A SYSFLAG_A GBV_SPRINGER GBV_ILN_11 GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_2003 GBV_ILN_2005 GBV_ILN_2009 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2027 GBV_ILN_2055 GBV_ILN_2108 GBV_ILN_2111 GBV_ILN_2119 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 19 2022 1 03 06
spelling	10.1186/s12984-022-01034-2 doi (DE-627)SPR050754076 (SPR)s12984-022-01034-2-e DE-627 ger DE-627 rakwb eng Shin, Sung Yul verfasserin aut Soft robotic exosuit augmented high intensity gait training on stroke survivors: a pilot study 2022 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier © The Author(s) 2022. corrected publication 2022 Background Stroke is a leading cause of serious gait impairments and restoring walking ability is a major goal of physical therapy interventions. Soft robotic exosuits are portable, lightweight, and unobtrusive assistive devices designed to improve the mobility of post-stroke individuals through facilitation of more natural paretic limb function during walking training. However, it is unknown whether long-term gait training using soft robotic exosuits will clinically impact gait function and quality of movement post-stroke. Objective The objective of this pilot study was to examine the therapeutic effects of soft robotic exosuit-augmented gait training on clinical and biomechanical gait outcomes in chronic post-stroke individuals. Methods Five post-stroke individuals received high intensity gait training augmented with a soft robotic exosuit, delivered in 18 sessions over 6–8 weeks. Performance based clinical outcomes and biomechanical gait quality parameters were measured at baseline, midpoint, and completion. Results Clinically meaningful improvements were observed in walking speed (%$p%$ < 0.05) and endurance (%$p%$ < 0.01) together with other traditional gait related outcomes. The gait quality measures including hip (%$p%$ < 0.01) and knee (%$p%$ < 0.05) flexion/extension exhibited an increase in range of motion in a symmetric manner (%$p%$ < 0.05). We also observed an increase in bilateral ankle angular velocities (%$p%$ < 0.05), suggesting biomechanical improvements in walking function. Conclusions The results in this study offer preliminary evidence that a soft robotic exosuit can be a useful tool to augment high intensity gait training in a clinical setting. This study justifies more expanded research on soft exosuit technology with a larger post-stroke population for more reliable generalization. Trial registration This study is registered with ClinicalTrials.gov (ID: NCT04251091) Exosuit (dpeaa)DE-He213 Soft robotics (dpeaa)DE-He213 High intensity gait training (dpeaa)DE-He213 Clinical outcomes (dpeaa)DE-He213 Gait quality (dpeaa)DE-He213 Stroke (dpeaa)DE-He213 Hohl, Kristen aut Giffhorn, Matt aut Awad, Louis N. aut Walsh, Conor J. aut Jayaraman, Arun aut Enthalten in Journal of neuroEngineering and rehabilitation London : BioMed Central, 2004 19(2022), 1 vom: 03. Juni (DE-627)461907933 (DE-600)2164377-5 1743-0003 nnns volume:19 year:2022 number:1 day:03 month:06 https://dx.doi.org/10.1186/s12984-022-01034-2 kostenfrei Volltext GBV_USEFLAG_A SYSFLAG_A GBV_SPRINGER GBV_ILN_11 GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_2003 GBV_ILN_2005 GBV_ILN_2009 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2027 GBV_ILN_2055 GBV_ILN_2108 GBV_ILN_2111 GBV_ILN_2119 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 19 2022 1 03 06
allfields_unstemmed	10.1186/s12984-022-01034-2 doi (DE-627)SPR050754076 (SPR)s12984-022-01034-2-e DE-627 ger DE-627 rakwb eng Shin, Sung Yul verfasserin aut Soft robotic exosuit augmented high intensity gait training on stroke survivors: a pilot study 2022 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier © The Author(s) 2022. corrected publication 2022 Background Stroke is a leading cause of serious gait impairments and restoring walking ability is a major goal of physical therapy interventions. Soft robotic exosuits are portable, lightweight, and unobtrusive assistive devices designed to improve the mobility of post-stroke individuals through facilitation of more natural paretic limb function during walking training. However, it is unknown whether long-term gait training using soft robotic exosuits will clinically impact gait function and quality of movement post-stroke. Objective The objective of this pilot study was to examine the therapeutic effects of soft robotic exosuit-augmented gait training on clinical and biomechanical gait outcomes in chronic post-stroke individuals. Methods Five post-stroke individuals received high intensity gait training augmented with a soft robotic exosuit, delivered in 18 sessions over 6–8 weeks. Performance based clinical outcomes and biomechanical gait quality parameters were measured at baseline, midpoint, and completion. Results Clinically meaningful improvements were observed in walking speed (%$p%$ < 0.05) and endurance (%$p%$ < 0.01) together with other traditional gait related outcomes. The gait quality measures including hip (%$p%$ < 0.01) and knee (%$p%$ < 0.05) flexion/extension exhibited an increase in range of motion in a symmetric manner (%$p%$ < 0.05). We also observed an increase in bilateral ankle angular velocities (%$p%$ < 0.05), suggesting biomechanical improvements in walking function. Conclusions The results in this study offer preliminary evidence that a soft robotic exosuit can be a useful tool to augment high intensity gait training in a clinical setting. This study justifies more expanded research on soft exosuit technology with a larger post-stroke population for more reliable generalization. Trial registration This study is registered with ClinicalTrials.gov (ID: NCT04251091) Exosuit (dpeaa)DE-He213 Soft robotics (dpeaa)DE-He213 High intensity gait training (dpeaa)DE-He213 Clinical outcomes (dpeaa)DE-He213 Gait quality (dpeaa)DE-He213 Stroke (dpeaa)DE-He213 Hohl, Kristen aut Giffhorn, Matt aut Awad, Louis N. aut Walsh, Conor J. aut Jayaraman, Arun aut Enthalten in Journal of neuroEngineering and rehabilitation London : BioMed Central, 2004 19(2022), 1 vom: 03. Juni (DE-627)461907933 (DE-600)2164377-5 1743-0003 nnns volume:19 year:2022 number:1 day:03 month:06 https://dx.doi.org/10.1186/s12984-022-01034-2 kostenfrei Volltext GBV_USEFLAG_A SYSFLAG_A GBV_SPRINGER GBV_ILN_11 GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_2003 GBV_ILN_2005 GBV_ILN_2009 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2027 GBV_ILN_2055 GBV_ILN_2108 GBV_ILN_2111 GBV_ILN_2119 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 19 2022 1 03 06
allfieldsGer	10.1186/s12984-022-01034-2 doi (DE-627)SPR050754076 (SPR)s12984-022-01034-2-e DE-627 ger DE-627 rakwb eng Shin, Sung Yul verfasserin aut Soft robotic exosuit augmented high intensity gait training on stroke survivors: a pilot study 2022 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier © The Author(s) 2022. corrected publication 2022 Background Stroke is a leading cause of serious gait impairments and restoring walking ability is a major goal of physical therapy interventions. Soft robotic exosuits are portable, lightweight, and unobtrusive assistive devices designed to improve the mobility of post-stroke individuals through facilitation of more natural paretic limb function during walking training. However, it is unknown whether long-term gait training using soft robotic exosuits will clinically impact gait function and quality of movement post-stroke. Objective The objective of this pilot study was to examine the therapeutic effects of soft robotic exosuit-augmented gait training on clinical and biomechanical gait outcomes in chronic post-stroke individuals. Methods Five post-stroke individuals received high intensity gait training augmented with a soft robotic exosuit, delivered in 18 sessions over 6–8 weeks. Performance based clinical outcomes and biomechanical gait quality parameters were measured at baseline, midpoint, and completion. Results Clinically meaningful improvements were observed in walking speed (%$p%$ < 0.05) and endurance (%$p%$ < 0.01) together with other traditional gait related outcomes. The gait quality measures including hip (%$p%$ < 0.01) and knee (%$p%$ < 0.05) flexion/extension exhibited an increase in range of motion in a symmetric manner (%$p%$ < 0.05). We also observed an increase in bilateral ankle angular velocities (%$p%$ < 0.05), suggesting biomechanical improvements in walking function. Conclusions The results in this study offer preliminary evidence that a soft robotic exosuit can be a useful tool to augment high intensity gait training in a clinical setting. This study justifies more expanded research on soft exosuit technology with a larger post-stroke population for more reliable generalization. Trial registration This study is registered with ClinicalTrials.gov (ID: NCT04251091) Exosuit (dpeaa)DE-He213 Soft robotics (dpeaa)DE-He213 High intensity gait training (dpeaa)DE-He213 Clinical outcomes (dpeaa)DE-He213 Gait quality (dpeaa)DE-He213 Stroke (dpeaa)DE-He213 Hohl, Kristen aut Giffhorn, Matt aut Awad, Louis N. aut Walsh, Conor J. aut Jayaraman, Arun aut Enthalten in Journal of neuroEngineering and rehabilitation London : BioMed Central, 2004 19(2022), 1 vom: 03. Juni (DE-627)461907933 (DE-600)2164377-5 1743-0003 nnns volume:19 year:2022 number:1 day:03 month:06 https://dx.doi.org/10.1186/s12984-022-01034-2 kostenfrei Volltext GBV_USEFLAG_A SYSFLAG_A GBV_SPRINGER GBV_ILN_11 GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_2003 GBV_ILN_2005 GBV_ILN_2009 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2027 GBV_ILN_2055 GBV_ILN_2108 GBV_ILN_2111 GBV_ILN_2119 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 19 2022 1 03 06
allfieldsSound	10.1186/s12984-022-01034-2 doi (DE-627)SPR050754076 (SPR)s12984-022-01034-2-e DE-627 ger DE-627 rakwb eng Shin, Sung Yul verfasserin aut Soft robotic exosuit augmented high intensity gait training on stroke survivors: a pilot study 2022 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier © The Author(s) 2022. corrected publication 2022 Background Stroke is a leading cause of serious gait impairments and restoring walking ability is a major goal of physical therapy interventions. Soft robotic exosuits are portable, lightweight, and unobtrusive assistive devices designed to improve the mobility of post-stroke individuals through facilitation of more natural paretic limb function during walking training. However, it is unknown whether long-term gait training using soft robotic exosuits will clinically impact gait function and quality of movement post-stroke. Objective The objective of this pilot study was to examine the therapeutic effects of soft robotic exosuit-augmented gait training on clinical and biomechanical gait outcomes in chronic post-stroke individuals. Methods Five post-stroke individuals received high intensity gait training augmented with a soft robotic exosuit, delivered in 18 sessions over 6–8 weeks. Performance based clinical outcomes and biomechanical gait quality parameters were measured at baseline, midpoint, and completion. Results Clinically meaningful improvements were observed in walking speed (%$p%$ < 0.05) and endurance (%$p%$ < 0.01) together with other traditional gait related outcomes. The gait quality measures including hip (%$p%$ < 0.01) and knee (%$p%$ < 0.05) flexion/extension exhibited an increase in range of motion in a symmetric manner (%$p%$ < 0.05). We also observed an increase in bilateral ankle angular velocities (%$p%$ < 0.05), suggesting biomechanical improvements in walking function. Conclusions The results in this study offer preliminary evidence that a soft robotic exosuit can be a useful tool to augment high intensity gait training in a clinical setting. This study justifies more expanded research on soft exosuit technology with a larger post-stroke population for more reliable generalization. Trial registration This study is registered with ClinicalTrials.gov (ID: NCT04251091) Exosuit (dpeaa)DE-He213 Soft robotics (dpeaa)DE-He213 High intensity gait training (dpeaa)DE-He213 Clinical outcomes (dpeaa)DE-He213 Gait quality (dpeaa)DE-He213 Stroke (dpeaa)DE-He213 Hohl, Kristen aut Giffhorn, Matt aut Awad, Louis N. aut Walsh, Conor J. aut Jayaraman, Arun aut Enthalten in Journal of neuroEngineering and rehabilitation London : BioMed Central, 2004 19(2022), 1 vom: 03. Juni (DE-627)461907933 (DE-600)2164377-5 1743-0003 nnns volume:19 year:2022 number:1 day:03 month:06 https://dx.doi.org/10.1186/s12984-022-01034-2 kostenfrei Volltext GBV_USEFLAG_A SYSFLAG_A GBV_SPRINGER GBV_ILN_11 GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_2003 GBV_ILN_2005 GBV_ILN_2009 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2027 GBV_ILN_2055 GBV_ILN_2108 GBV_ILN_2111 GBV_ILN_2119 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 19 2022 1 03 06
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Soft robotic exosuits are portable, lightweight, and unobtrusive assistive devices designed to improve the mobility of post-stroke individuals through facilitation of more natural paretic limb function during walking training. However, it is unknown whether long-term gait training using soft robotic exosuits will clinically impact gait function and quality of movement post-stroke. Objective The objective of this pilot study was to examine the therapeutic effects of soft robotic exosuit-augmented gait training on clinical and biomechanical gait outcomes in chronic post-stroke individuals. Methods Five post-stroke individuals received high intensity gait training augmented with a soft robotic exosuit, delivered in 18 sessions over 6–8 weeks. Performance based clinical outcomes and biomechanical gait quality parameters were measured at baseline, midpoint, and completion. Results Clinically meaningful improvements were observed in walking speed (%$p%$ < 0.05) and endurance (%$p%$ < 0.01) together with other traditional gait related outcomes. The gait quality measures including hip (%$p%$ < 0.01) and knee (%$p%$ < 0.05) flexion/extension exhibited an increase in range of motion in a symmetric manner (%$p%$ < 0.05). We also observed an increase in bilateral ankle angular velocities (%$p%$ < 0.05), suggesting biomechanical improvements in walking function. Conclusions The results in this study offer preliminary evidence that a soft robotic exosuit can be a useful tool to augment high intensity gait training in a clinical setting. This study justifies more expanded research on soft exosuit technology with a larger post-stroke population for more reliable generalization. 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author	Shin, Sung Yul
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topic_title	Soft robotic exosuit augmented high intensity gait training on stroke survivors: a pilot study Exosuit (dpeaa)DE-He213 Soft robotics (dpeaa)DE-He213 High intensity gait training (dpeaa)DE-He213 Clinical outcomes (dpeaa)DE-He213 Gait quality (dpeaa)DE-He213 Stroke (dpeaa)DE-He213
topic	misc Exosuit misc Soft robotics misc High intensity gait training misc Clinical outcomes misc Gait quality misc Stroke
topic_unstemmed	misc Exosuit misc Soft robotics misc High intensity gait training misc Clinical outcomes misc Gait quality misc Stroke
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title	Soft robotic exosuit augmented high intensity gait training on stroke survivors: a pilot study
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title_full	Soft robotic exosuit augmented high intensity gait training on stroke survivors: a pilot study
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title_sort	soft robotic exosuit augmented high intensity gait training on stroke survivors: a pilot study
title_auth	Soft robotic exosuit augmented high intensity gait training on stroke survivors: a pilot study
abstract	Background Stroke is a leading cause of serious gait impairments and restoring walking ability is a major goal of physical therapy interventions. Soft robotic exosuits are portable, lightweight, and unobtrusive assistive devices designed to improve the mobility of post-stroke individuals through facilitation of more natural paretic limb function during walking training. However, it is unknown whether long-term gait training using soft robotic exosuits will clinically impact gait function and quality of movement post-stroke. Objective The objective of this pilot study was to examine the therapeutic effects of soft robotic exosuit-augmented gait training on clinical and biomechanical gait outcomes in chronic post-stroke individuals. Methods Five post-stroke individuals received high intensity gait training augmented with a soft robotic exosuit, delivered in 18 sessions over 6–8 weeks. Performance based clinical outcomes and biomechanical gait quality parameters were measured at baseline, midpoint, and completion. Results Clinically meaningful improvements were observed in walking speed (%$p%$ < 0.05) and endurance (%$p%$ < 0.01) together with other traditional gait related outcomes. The gait quality measures including hip (%$p%$ < 0.01) and knee (%$p%$ < 0.05) flexion/extension exhibited an increase in range of motion in a symmetric manner (%$p%$ < 0.05). We also observed an increase in bilateral ankle angular velocities (%$p%$ < 0.05), suggesting biomechanical improvements in walking function. Conclusions The results in this study offer preliminary evidence that a soft robotic exosuit can be a useful tool to augment high intensity gait training in a clinical setting. This study justifies more expanded research on soft exosuit technology with a larger post-stroke population for more reliable generalization. Trial registration This study is registered with ClinicalTrials.gov (ID: NCT04251091) © The Author(s) 2022. corrected publication 2022
abstractGer	Background Stroke is a leading cause of serious gait impairments and restoring walking ability is a major goal of physical therapy interventions. Soft robotic exosuits are portable, lightweight, and unobtrusive assistive devices designed to improve the mobility of post-stroke individuals through facilitation of more natural paretic limb function during walking training. However, it is unknown whether long-term gait training using soft robotic exosuits will clinically impact gait function and quality of movement post-stroke. Objective The objective of this pilot study was to examine the therapeutic effects of soft robotic exosuit-augmented gait training on clinical and biomechanical gait outcomes in chronic post-stroke individuals. Methods Five post-stroke individuals received high intensity gait training augmented with a soft robotic exosuit, delivered in 18 sessions over 6–8 weeks. Performance based clinical outcomes and biomechanical gait quality parameters were measured at baseline, midpoint, and completion. Results Clinically meaningful improvements were observed in walking speed (%$p%$ < 0.05) and endurance (%$p%$ < 0.01) together with other traditional gait related outcomes. The gait quality measures including hip (%$p%$ < 0.01) and knee (%$p%$ < 0.05) flexion/extension exhibited an increase in range of motion in a symmetric manner (%$p%$ < 0.05). We also observed an increase in bilateral ankle angular velocities (%$p%$ < 0.05), suggesting biomechanical improvements in walking function. Conclusions The results in this study offer preliminary evidence that a soft robotic exosuit can be a useful tool to augment high intensity gait training in a clinical setting. This study justifies more expanded research on soft exosuit technology with a larger post-stroke population for more reliable generalization. Trial registration This study is registered with ClinicalTrials.gov (ID: NCT04251091) © The Author(s) 2022. corrected publication 2022
abstract_unstemmed	Background Stroke is a leading cause of serious gait impairments and restoring walking ability is a major goal of physical therapy interventions. Soft robotic exosuits are portable, lightweight, and unobtrusive assistive devices designed to improve the mobility of post-stroke individuals through facilitation of more natural paretic limb function during walking training. However, it is unknown whether long-term gait training using soft robotic exosuits will clinically impact gait function and quality of movement post-stroke. Objective The objective of this pilot study was to examine the therapeutic effects of soft robotic exosuit-augmented gait training on clinical and biomechanical gait outcomes in chronic post-stroke individuals. Methods Five post-stroke individuals received high intensity gait training augmented with a soft robotic exosuit, delivered in 18 sessions over 6–8 weeks. Performance based clinical outcomes and biomechanical gait quality parameters were measured at baseline, midpoint, and completion. Results Clinically meaningful improvements were observed in walking speed (%$p%$ < 0.05) and endurance (%$p%$ < 0.01) together with other traditional gait related outcomes. The gait quality measures including hip (%$p%$ < 0.01) and knee (%$p%$ < 0.05) flexion/extension exhibited an increase in range of motion in a symmetric manner (%$p%$ < 0.05). We also observed an increase in bilateral ankle angular velocities (%$p%$ < 0.05), suggesting biomechanical improvements in walking function. Conclusions The results in this study offer preliminary evidence that a soft robotic exosuit can be a useful tool to augment high intensity gait training in a clinical setting. This study justifies more expanded research on soft exosuit technology with a larger post-stroke population for more reliable generalization. Trial registration This study is registered with ClinicalTrials.gov (ID: NCT04251091) © The Author(s) 2022. corrected publication 2022
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title_short	Soft robotic exosuit augmented high intensity gait training on stroke survivors: a pilot study
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Soft robotic exosuits are portable, lightweight, and unobtrusive assistive devices designed to improve the mobility of post-stroke individuals through facilitation of more natural paretic limb function during walking training. However, it is unknown whether long-term gait training using soft robotic exosuits will clinically impact gait function and quality of movement post-stroke. Objective The objective of this pilot study was to examine the therapeutic effects of soft robotic exosuit-augmented gait training on clinical and biomechanical gait outcomes in chronic post-stroke individuals. Methods Five post-stroke individuals received high intensity gait training augmented with a soft robotic exosuit, delivered in 18 sessions over 6–8 weeks. Performance based clinical outcomes and biomechanical gait quality parameters were measured at baseline, midpoint, and completion. Results Clinically meaningful improvements were observed in walking speed (%$p%$ < 0.05) and endurance (%$p%$ < 0.01) together with other traditional gait related outcomes. The gait quality measures including hip (%$p%$ < 0.01) and knee (%$p%$ < 0.05) flexion/extension exhibited an increase in range of motion in a symmetric manner (%$p%$ < 0.05). We also observed an increase in bilateral ankle angular velocities (%$p%$ < 0.05), suggesting biomechanical improvements in walking function. Conclusions The results in this study offer preliminary evidence that a soft robotic exosuit can be a useful tool to augment high intensity gait training in a clinical setting. This study justifies more expanded research on soft exosuit technology with a larger post-stroke population for more reliable generalization. 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Soft robotic exosuit augmented high intensity gait training on stroke survivors: a pilot study

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