Mitral and aortic valve regurgitation following surgical and transcatheter perimembranous ventricular septal defect closure in children and adolescents: midterm outcomes

Background Closure of perimembranous ventricular septal defects (pmVSD), either surgical or percutaneous, might improve or cause new-onset mitral regurgitation (MR) and aortic regurgitation (AR). We aimed to evaluate the changes in MR and AR after pmVSD closure by these two methods. Material and met...
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Autor*in:	Edraki, Mohammadreza [verfasserIn] Nobakhti, Mohammadjavad Naghshzan, Amir Amoozgar, Hamid Amirghofran, Ahmadali Ghasemzadeh, Bahram Nirooie, Elahe Mehdizadegan, Nima Mohammadi, Hamid Keshavarz, Kambiz

Format:	E-Artikel
Sprache:	Englisch

Erschienen:	2022

Schlagwörter:	Ventricular septal defect Surgical closure Percutaneous closure Amplatzer Mitral regurgitation Aortic regurgitation

Anmerkung:	© The Author(s) 2022. corrected publication 2022

Übergeordnetes Werk:	Enthalten in: BMC cardiovascular disorders - London : BioMed Central, 2001, 22(2022), 1 vom: 15. Juli
Übergeordnetes Werk:	volume:22 ; year:2022 ; number:1 ; day:15 ; month:07

Links:	Volltext

DOI / URN:	10.1186/s12872-022-02757-9

Katalog-ID:	SPR050855387

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245	1	0	\|a Mitral and aortic valve regurgitation following surgical and transcatheter perimembranous ventricular septal defect closure in children and adolescents: midterm outcomes
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520			\|a Background Closure of perimembranous ventricular septal defects (pmVSD), either surgical or percutaneous, might improve or cause new-onset mitral regurgitation (MR) and aortic regurgitation (AR). We aimed to evaluate the changes in MR and AR after pmVSD closure by these two methods. Material and method We performed a comparative retrospective data review of all pediatric patients with pmVSDs treated at our institution with surgical or antegrade percutaneous methods from 2014 to 2019 and 146 consecutive patients under 18 years were enrolled. We closely looked at the mitral and aortic valve function after repair. Included patients had no or lower than moderate aortic valve prolapse and baseline normal mitral or aortic valve function or less than moderate MR or AR. Results Out of 146 patients, 83 (57%) pmVSDs were closed percutaneously, and 63 (43%) pmVSDs were closed surgically. 80 and 62 patients were included for MR evaluation, and 81 and 62 patients for AR evaluation in percutaneous and surgical groups. The mean follow-up time was 40.48 ± 21.59 months in the surgery group and 20.44 ± 18.66 months in the transcatheter group. Mild to moderate degrees of MR and AR did not change or decreased in most patients. In detail, MR of 70% and AR of 50% of the valves were resolved or decreased in both groups. 13% of patients with no MR developed trivial to mild MR, and 10% of patients with no AR showed mild to moderate AR after pmVSD closure in both methods. There was no significant difference between the two methods regarding emerging new regurgitation or change in the severity of the previous regurgitation. Conclusion pmVSD closure usually improves mild to moderate MR and AR to a nearly similar extent in both percutaneous and surgical methods among children and adolescents. It might lead to the onset of new MR or AR in cases with no regurgitation.
650		4	\|a Ventricular septal defect \|7 (dpeaa)DE-He213
650		4	\|a Surgical closure \|7 (dpeaa)DE-He213
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650		4	\|a Amplatzer \|7 (dpeaa)DE-He213
650		4	\|a Mitral regurgitation \|7 (dpeaa)DE-He213
650		4	\|a Aortic regurgitation \|7 (dpeaa)DE-He213
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700	1		\|a Keshavarz, Kambiz \|4 aut
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allfields	10.1186/s12872-022-02757-9 doi (DE-627)SPR050855387 (SPR)s12872-022-02757-9-e DE-627 ger DE-627 rakwb eng Edraki, Mohammadreza verfasserin aut Mitral and aortic valve regurgitation following surgical and transcatheter perimembranous ventricular septal defect closure in children and adolescents: midterm outcomes 2022 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier © The Author(s) 2022. corrected publication 2022 Background Closure of perimembranous ventricular septal defects (pmVSD), either surgical or percutaneous, might improve or cause new-onset mitral regurgitation (MR) and aortic regurgitation (AR). We aimed to evaluate the changes in MR and AR after pmVSD closure by these two methods. Material and method We performed a comparative retrospective data review of all pediatric patients with pmVSDs treated at our institution with surgical or antegrade percutaneous methods from 2014 to 2019 and 146 consecutive patients under 18 years were enrolled. We closely looked at the mitral and aortic valve function after repair. Included patients had no or lower than moderate aortic valve prolapse and baseline normal mitral or aortic valve function or less than moderate MR or AR. Results Out of 146 patients, 83 (57%) pmVSDs were closed percutaneously, and 63 (43%) pmVSDs were closed surgically. 80 and 62 patients were included for MR evaluation, and 81 and 62 patients for AR evaluation in percutaneous and surgical groups. The mean follow-up time was 40.48 ± 21.59 months in the surgery group and 20.44 ± 18.66 months in the transcatheter group. Mild to moderate degrees of MR and AR did not change or decreased in most patients. In detail, MR of 70% and AR of 50% of the valves were resolved or decreased in both groups. 13% of patients with no MR developed trivial to mild MR, and 10% of patients with no AR showed mild to moderate AR after pmVSD closure in both methods. There was no significant difference between the two methods regarding emerging new regurgitation or change in the severity of the previous regurgitation. Conclusion pmVSD closure usually improves mild to moderate MR and AR to a nearly similar extent in both percutaneous and surgical methods among children and adolescents. It might lead to the onset of new MR or AR in cases with no regurgitation. Ventricular septal defect (dpeaa)DE-He213 Surgical closure (dpeaa)DE-He213 Percutaneous closure (dpeaa)DE-He213 Amplatzer (dpeaa)DE-He213 Mitral regurgitation (dpeaa)DE-He213 Aortic regurgitation (dpeaa)DE-He213 Nobakhti, Mohammadjavad aut Naghshzan, Amir (orcid)0000-0001-7647-178X aut Amoozgar, Hamid aut Amirghofran, Ahmadali aut Ghasemzadeh, Bahram aut Nirooie, Elahe aut Mehdizadegan, Nima aut Mohammadi, Hamid aut Keshavarz, Kambiz aut Enthalten in BMC cardiovascular disorders London : BioMed Central, 2001 22(2022), 1 vom: 15. Juli (DE-627)335488870 (DE-600)2059859-2 1471-2261 nnns volume:22 year:2022 number:1 day:15 month:07 https://dx.doi.org/10.1186/s12872-022-02757-9 kostenfrei Volltext GBV_USEFLAG_A SYSFLAG_A GBV_SPRINGER GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_2014 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 22 2022 1 15 07
spelling	10.1186/s12872-022-02757-9 doi (DE-627)SPR050855387 (SPR)s12872-022-02757-9-e DE-627 ger DE-627 rakwb eng Edraki, Mohammadreza verfasserin aut Mitral and aortic valve regurgitation following surgical and transcatheter perimembranous ventricular septal defect closure in children and adolescents: midterm outcomes 2022 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier © The Author(s) 2022. corrected publication 2022 Background Closure of perimembranous ventricular septal defects (pmVSD), either surgical or percutaneous, might improve or cause new-onset mitral regurgitation (MR) and aortic regurgitation (AR). We aimed to evaluate the changes in MR and AR after pmVSD closure by these two methods. Material and method We performed a comparative retrospective data review of all pediatric patients with pmVSDs treated at our institution with surgical or antegrade percutaneous methods from 2014 to 2019 and 146 consecutive patients under 18 years were enrolled. We closely looked at the mitral and aortic valve function after repair. Included patients had no or lower than moderate aortic valve prolapse and baseline normal mitral or aortic valve function or less than moderate MR or AR. Results Out of 146 patients, 83 (57%) pmVSDs were closed percutaneously, and 63 (43%) pmVSDs were closed surgically. 80 and 62 patients were included for MR evaluation, and 81 and 62 patients for AR evaluation in percutaneous and surgical groups. The mean follow-up time was 40.48 ± 21.59 months in the surgery group and 20.44 ± 18.66 months in the transcatheter group. Mild to moderate degrees of MR and AR did not change or decreased in most patients. In detail, MR of 70% and AR of 50% of the valves were resolved or decreased in both groups. 13% of patients with no MR developed trivial to mild MR, and 10% of patients with no AR showed mild to moderate AR after pmVSD closure in both methods. There was no significant difference between the two methods regarding emerging new regurgitation or change in the severity of the previous regurgitation. Conclusion pmVSD closure usually improves mild to moderate MR and AR to a nearly similar extent in both percutaneous and surgical methods among children and adolescents. It might lead to the onset of new MR or AR in cases with no regurgitation. Ventricular septal defect (dpeaa)DE-He213 Surgical closure (dpeaa)DE-He213 Percutaneous closure (dpeaa)DE-He213 Amplatzer (dpeaa)DE-He213 Mitral regurgitation (dpeaa)DE-He213 Aortic regurgitation (dpeaa)DE-He213 Nobakhti, Mohammadjavad aut Naghshzan, Amir (orcid)0000-0001-7647-178X aut Amoozgar, Hamid aut Amirghofran, Ahmadali aut Ghasemzadeh, Bahram aut Nirooie, Elahe aut Mehdizadegan, Nima aut Mohammadi, Hamid aut Keshavarz, Kambiz aut Enthalten in BMC cardiovascular disorders London : BioMed Central, 2001 22(2022), 1 vom: 15. Juli (DE-627)335488870 (DE-600)2059859-2 1471-2261 nnns volume:22 year:2022 number:1 day:15 month:07 https://dx.doi.org/10.1186/s12872-022-02757-9 kostenfrei Volltext GBV_USEFLAG_A SYSFLAG_A GBV_SPRINGER GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_2014 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 22 2022 1 15 07
allfields_unstemmed	10.1186/s12872-022-02757-9 doi (DE-627)SPR050855387 (SPR)s12872-022-02757-9-e DE-627 ger DE-627 rakwb eng Edraki, Mohammadreza verfasserin aut Mitral and aortic valve regurgitation following surgical and transcatheter perimembranous ventricular septal defect closure in children and adolescents: midterm outcomes 2022 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier © The Author(s) 2022. corrected publication 2022 Background Closure of perimembranous ventricular septal defects (pmVSD), either surgical or percutaneous, might improve or cause new-onset mitral regurgitation (MR) and aortic regurgitation (AR). We aimed to evaluate the changes in MR and AR after pmVSD closure by these two methods. Material and method We performed a comparative retrospective data review of all pediatric patients with pmVSDs treated at our institution with surgical or antegrade percutaneous methods from 2014 to 2019 and 146 consecutive patients under 18 years were enrolled. We closely looked at the mitral and aortic valve function after repair. Included patients had no or lower than moderate aortic valve prolapse and baseline normal mitral or aortic valve function or less than moderate MR or AR. Results Out of 146 patients, 83 (57%) pmVSDs were closed percutaneously, and 63 (43%) pmVSDs were closed surgically. 80 and 62 patients were included for MR evaluation, and 81 and 62 patients for AR evaluation in percutaneous and surgical groups. The mean follow-up time was 40.48 ± 21.59 months in the surgery group and 20.44 ± 18.66 months in the transcatheter group. Mild to moderate degrees of MR and AR did not change or decreased in most patients. In detail, MR of 70% and AR of 50% of the valves were resolved or decreased in both groups. 13% of patients with no MR developed trivial to mild MR, and 10% of patients with no AR showed mild to moderate AR after pmVSD closure in both methods. There was no significant difference between the two methods regarding emerging new regurgitation or change in the severity of the previous regurgitation. Conclusion pmVSD closure usually improves mild to moderate MR and AR to a nearly similar extent in both percutaneous and surgical methods among children and adolescents. It might lead to the onset of new MR or AR in cases with no regurgitation. Ventricular septal defect (dpeaa)DE-He213 Surgical closure (dpeaa)DE-He213 Percutaneous closure (dpeaa)DE-He213 Amplatzer (dpeaa)DE-He213 Mitral regurgitation (dpeaa)DE-He213 Aortic regurgitation (dpeaa)DE-He213 Nobakhti, Mohammadjavad aut Naghshzan, Amir (orcid)0000-0001-7647-178X aut Amoozgar, Hamid aut Amirghofran, Ahmadali aut Ghasemzadeh, Bahram aut Nirooie, Elahe aut Mehdizadegan, Nima aut Mohammadi, Hamid aut Keshavarz, Kambiz aut Enthalten in BMC cardiovascular disorders London : BioMed Central, 2001 22(2022), 1 vom: 15. Juli (DE-627)335488870 (DE-600)2059859-2 1471-2261 nnns volume:22 year:2022 number:1 day:15 month:07 https://dx.doi.org/10.1186/s12872-022-02757-9 kostenfrei Volltext GBV_USEFLAG_A SYSFLAG_A GBV_SPRINGER GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_2014 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 22 2022 1 15 07
allfieldsGer	10.1186/s12872-022-02757-9 doi (DE-627)SPR050855387 (SPR)s12872-022-02757-9-e DE-627 ger DE-627 rakwb eng Edraki, Mohammadreza verfasserin aut Mitral and aortic valve regurgitation following surgical and transcatheter perimembranous ventricular septal defect closure in children and adolescents: midterm outcomes 2022 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier © The Author(s) 2022. corrected publication 2022 Background Closure of perimembranous ventricular septal defects (pmVSD), either surgical or percutaneous, might improve or cause new-onset mitral regurgitation (MR) and aortic regurgitation (AR). We aimed to evaluate the changes in MR and AR after pmVSD closure by these two methods. Material and method We performed a comparative retrospective data review of all pediatric patients with pmVSDs treated at our institution with surgical or antegrade percutaneous methods from 2014 to 2019 and 146 consecutive patients under 18 years were enrolled. We closely looked at the mitral and aortic valve function after repair. Included patients had no or lower than moderate aortic valve prolapse and baseline normal mitral or aortic valve function or less than moderate MR or AR. Results Out of 146 patients, 83 (57%) pmVSDs were closed percutaneously, and 63 (43%) pmVSDs were closed surgically. 80 and 62 patients were included for MR evaluation, and 81 and 62 patients for AR evaluation in percutaneous and surgical groups. The mean follow-up time was 40.48 ± 21.59 months in the surgery group and 20.44 ± 18.66 months in the transcatheter group. Mild to moderate degrees of MR and AR did not change or decreased in most patients. In detail, MR of 70% and AR of 50% of the valves were resolved or decreased in both groups. 13% of patients with no MR developed trivial to mild MR, and 10% of patients with no AR showed mild to moderate AR after pmVSD closure in both methods. There was no significant difference between the two methods regarding emerging new regurgitation or change in the severity of the previous regurgitation. Conclusion pmVSD closure usually improves mild to moderate MR and AR to a nearly similar extent in both percutaneous and surgical methods among children and adolescents. It might lead to the onset of new MR or AR in cases with no regurgitation. Ventricular septal defect (dpeaa)DE-He213 Surgical closure (dpeaa)DE-He213 Percutaneous closure (dpeaa)DE-He213 Amplatzer (dpeaa)DE-He213 Mitral regurgitation (dpeaa)DE-He213 Aortic regurgitation (dpeaa)DE-He213 Nobakhti, Mohammadjavad aut Naghshzan, Amir (orcid)0000-0001-7647-178X aut Amoozgar, Hamid aut Amirghofran, Ahmadali aut Ghasemzadeh, Bahram aut Nirooie, Elahe aut Mehdizadegan, Nima aut Mohammadi, Hamid aut Keshavarz, Kambiz aut Enthalten in BMC cardiovascular disorders London : BioMed Central, 2001 22(2022), 1 vom: 15. Juli (DE-627)335488870 (DE-600)2059859-2 1471-2261 nnns volume:22 year:2022 number:1 day:15 month:07 https://dx.doi.org/10.1186/s12872-022-02757-9 kostenfrei Volltext GBV_USEFLAG_A SYSFLAG_A GBV_SPRINGER GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_2014 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 22 2022 1 15 07
allfieldsSound	10.1186/s12872-022-02757-9 doi (DE-627)SPR050855387 (SPR)s12872-022-02757-9-e DE-627 ger DE-627 rakwb eng Edraki, Mohammadreza verfasserin aut Mitral and aortic valve regurgitation following surgical and transcatheter perimembranous ventricular septal defect closure in children and adolescents: midterm outcomes 2022 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier © The Author(s) 2022. corrected publication 2022 Background Closure of perimembranous ventricular septal defects (pmVSD), either surgical or percutaneous, might improve or cause new-onset mitral regurgitation (MR) and aortic regurgitation (AR). We aimed to evaluate the changes in MR and AR after pmVSD closure by these two methods. Material and method We performed a comparative retrospective data review of all pediatric patients with pmVSDs treated at our institution with surgical or antegrade percutaneous methods from 2014 to 2019 and 146 consecutive patients under 18 years were enrolled. We closely looked at the mitral and aortic valve function after repair. Included patients had no or lower than moderate aortic valve prolapse and baseline normal mitral or aortic valve function or less than moderate MR or AR. Results Out of 146 patients, 83 (57%) pmVSDs were closed percutaneously, and 63 (43%) pmVSDs were closed surgically. 80 and 62 patients were included for MR evaluation, and 81 and 62 patients for AR evaluation in percutaneous and surgical groups. The mean follow-up time was 40.48 ± 21.59 months in the surgery group and 20.44 ± 18.66 months in the transcatheter group. Mild to moderate degrees of MR and AR did not change or decreased in most patients. In detail, MR of 70% and AR of 50% of the valves were resolved or decreased in both groups. 13% of patients with no MR developed trivial to mild MR, and 10% of patients with no AR showed mild to moderate AR after pmVSD closure in both methods. There was no significant difference between the two methods regarding emerging new regurgitation or change in the severity of the previous regurgitation. Conclusion pmVSD closure usually improves mild to moderate MR and AR to a nearly similar extent in both percutaneous and surgical methods among children and adolescents. It might lead to the onset of new MR or AR in cases with no regurgitation. Ventricular septal defect (dpeaa)DE-He213 Surgical closure (dpeaa)DE-He213 Percutaneous closure (dpeaa)DE-He213 Amplatzer (dpeaa)DE-He213 Mitral regurgitation (dpeaa)DE-He213 Aortic regurgitation (dpeaa)DE-He213 Nobakhti, Mohammadjavad aut Naghshzan, Amir (orcid)0000-0001-7647-178X aut Amoozgar, Hamid aut Amirghofran, Ahmadali aut Ghasemzadeh, Bahram aut Nirooie, Elahe aut Mehdizadegan, Nima aut Mohammadi, Hamid aut Keshavarz, Kambiz aut Enthalten in BMC cardiovascular disorders London : BioMed Central, 2001 22(2022), 1 vom: 15. Juli (DE-627)335488870 (DE-600)2059859-2 1471-2261 nnns volume:22 year:2022 number:1 day:15 month:07 https://dx.doi.org/10.1186/s12872-022-02757-9 kostenfrei Volltext GBV_USEFLAG_A SYSFLAG_A GBV_SPRINGER GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_2014 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 22 2022 1 15 07
language	English
source	Enthalten in BMC cardiovascular disorders 22(2022), 1 vom: 15. Juli volume:22 year:2022 number:1 day:15 month:07
sourceStr	Enthalten in BMC cardiovascular disorders 22(2022), 1 vom: 15. Juli volume:22 year:2022 number:1 day:15 month:07
format_phy_str_mv	Article
institution	findex.gbv.de
topic_facet	Ventricular septal defect Surgical closure Percutaneous closure Amplatzer Mitral regurgitation Aortic regurgitation
isfreeaccess_bool	true
container_title	BMC cardiovascular disorders
authorswithroles_txt_mv	Edraki, Mohammadreza @@aut@@ Nobakhti, Mohammadjavad @@aut@@ Naghshzan, Amir @@aut@@ Amoozgar, Hamid @@aut@@ Amirghofran, Ahmadali @@aut@@ Ghasemzadeh, Bahram @@aut@@ Nirooie, Elahe @@aut@@ Mehdizadegan, Nima @@aut@@ Mohammadi, Hamid @@aut@@ Keshavarz, Kambiz @@aut@@
publishDateDaySort_date	2022-07-15T00:00:00Z
hierarchy_top_id	335488870
id	SPR050855387
language_de	englisch
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author	Edraki, Mohammadreza
spellingShingle	Edraki, Mohammadreza misc Ventricular septal defect misc Surgical closure misc Percutaneous closure misc Amplatzer misc Mitral regurgitation misc Aortic regurgitation Mitral and aortic valve regurgitation following surgical and transcatheter perimembranous ventricular septal defect closure in children and adolescents: midterm outcomes
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topic_title	Mitral and aortic valve regurgitation following surgical and transcatheter perimembranous ventricular septal defect closure in children and adolescents: midterm outcomes Ventricular septal defect (dpeaa)DE-He213 Surgical closure (dpeaa)DE-He213 Percutaneous closure (dpeaa)DE-He213 Amplatzer (dpeaa)DE-He213 Mitral regurgitation (dpeaa)DE-He213 Aortic regurgitation (dpeaa)DE-He213
topic	misc Ventricular septal defect misc Surgical closure misc Percutaneous closure misc Amplatzer misc Mitral regurgitation misc Aortic regurgitation
topic_unstemmed	misc Ventricular septal defect misc Surgical closure misc Percutaneous closure misc Amplatzer misc Mitral regurgitation misc Aortic regurgitation
topic_browse	misc Ventricular septal defect misc Surgical closure misc Percutaneous closure misc Amplatzer misc Mitral regurgitation misc Aortic regurgitation
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title	Mitral and aortic valve regurgitation following surgical and transcatheter perimembranous ventricular septal defect closure in children and adolescents: midterm outcomes
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title_full	Mitral and aortic valve regurgitation following surgical and transcatheter perimembranous ventricular septal defect closure in children and adolescents: midterm outcomes
author_sort	Edraki, Mohammadreza
journal	BMC cardiovascular disorders
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author_browse	Edraki, Mohammadreza Nobakhti, Mohammadjavad Naghshzan, Amir Amoozgar, Hamid Amirghofran, Ahmadali Ghasemzadeh, Bahram Nirooie, Elahe Mehdizadegan, Nima Mohammadi, Hamid Keshavarz, Kambiz
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author-letter	Edraki, Mohammadreza
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title_sort	mitral and aortic valve regurgitation following surgical and transcatheter perimembranous ventricular septal defect closure in children and adolescents: midterm outcomes
title_auth	Mitral and aortic valve regurgitation following surgical and transcatheter perimembranous ventricular septal defect closure in children and adolescents: midterm outcomes
abstract	Background Closure of perimembranous ventricular septal defects (pmVSD), either surgical or percutaneous, might improve or cause new-onset mitral regurgitation (MR) and aortic regurgitation (AR). We aimed to evaluate the changes in MR and AR after pmVSD closure by these two methods. Material and method We performed a comparative retrospective data review of all pediatric patients with pmVSDs treated at our institution with surgical or antegrade percutaneous methods from 2014 to 2019 and 146 consecutive patients under 18 years were enrolled. We closely looked at the mitral and aortic valve function after repair. Included patients had no or lower than moderate aortic valve prolapse and baseline normal mitral or aortic valve function or less than moderate MR or AR. Results Out of 146 patients, 83 (57%) pmVSDs were closed percutaneously, and 63 (43%) pmVSDs were closed surgically. 80 and 62 patients were included for MR evaluation, and 81 and 62 patients for AR evaluation in percutaneous and surgical groups. The mean follow-up time was 40.48 ± 21.59 months in the surgery group and 20.44 ± 18.66 months in the transcatheter group. Mild to moderate degrees of MR and AR did not change or decreased in most patients. In detail, MR of 70% and AR of 50% of the valves were resolved or decreased in both groups. 13% of patients with no MR developed trivial to mild MR, and 10% of patients with no AR showed mild to moderate AR after pmVSD closure in both methods. There was no significant difference between the two methods regarding emerging new regurgitation or change in the severity of the previous regurgitation. Conclusion pmVSD closure usually improves mild to moderate MR and AR to a nearly similar extent in both percutaneous and surgical methods among children and adolescents. It might lead to the onset of new MR or AR in cases with no regurgitation. © The Author(s) 2022. corrected publication 2022
abstractGer	Background Closure of perimembranous ventricular septal defects (pmVSD), either surgical or percutaneous, might improve or cause new-onset mitral regurgitation (MR) and aortic regurgitation (AR). We aimed to evaluate the changes in MR and AR after pmVSD closure by these two methods. Material and method We performed a comparative retrospective data review of all pediatric patients with pmVSDs treated at our institution with surgical or antegrade percutaneous methods from 2014 to 2019 and 146 consecutive patients under 18 years were enrolled. We closely looked at the mitral and aortic valve function after repair. Included patients had no or lower than moderate aortic valve prolapse and baseline normal mitral or aortic valve function or less than moderate MR or AR. Results Out of 146 patients, 83 (57%) pmVSDs were closed percutaneously, and 63 (43%) pmVSDs were closed surgically. 80 and 62 patients were included for MR evaluation, and 81 and 62 patients for AR evaluation in percutaneous and surgical groups. The mean follow-up time was 40.48 ± 21.59 months in the surgery group and 20.44 ± 18.66 months in the transcatheter group. Mild to moderate degrees of MR and AR did not change or decreased in most patients. In detail, MR of 70% and AR of 50% of the valves were resolved or decreased in both groups. 13% of patients with no MR developed trivial to mild MR, and 10% of patients with no AR showed mild to moderate AR after pmVSD closure in both methods. There was no significant difference between the two methods regarding emerging new regurgitation or change in the severity of the previous regurgitation. Conclusion pmVSD closure usually improves mild to moderate MR and AR to a nearly similar extent in both percutaneous and surgical methods among children and adolescents. It might lead to the onset of new MR or AR in cases with no regurgitation. © The Author(s) 2022. corrected publication 2022
abstract_unstemmed	Background Closure of perimembranous ventricular septal defects (pmVSD), either surgical or percutaneous, might improve or cause new-onset mitral regurgitation (MR) and aortic regurgitation (AR). We aimed to evaluate the changes in MR and AR after pmVSD closure by these two methods. Material and method We performed a comparative retrospective data review of all pediatric patients with pmVSDs treated at our institution with surgical or antegrade percutaneous methods from 2014 to 2019 and 146 consecutive patients under 18 years were enrolled. We closely looked at the mitral and aortic valve function after repair. Included patients had no or lower than moderate aortic valve prolapse and baseline normal mitral or aortic valve function or less than moderate MR or AR. Results Out of 146 patients, 83 (57%) pmVSDs were closed percutaneously, and 63 (43%) pmVSDs were closed surgically. 80 and 62 patients were included for MR evaluation, and 81 and 62 patients for AR evaluation in percutaneous and surgical groups. The mean follow-up time was 40.48 ± 21.59 months in the surgery group and 20.44 ± 18.66 months in the transcatheter group. Mild to moderate degrees of MR and AR did not change or decreased in most patients. In detail, MR of 70% and AR of 50% of the valves were resolved or decreased in both groups. 13% of patients with no MR developed trivial to mild MR, and 10% of patients with no AR showed mild to moderate AR after pmVSD closure in both methods. There was no significant difference between the two methods regarding emerging new regurgitation or change in the severity of the previous regurgitation. Conclusion pmVSD closure usually improves mild to moderate MR and AR to a nearly similar extent in both percutaneous and surgical methods among children and adolescents. It might lead to the onset of new MR or AR in cases with no regurgitation. © The Author(s) 2022. corrected publication 2022
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title_short	Mitral and aortic valve regurgitation following surgical and transcatheter perimembranous ventricular septal defect closure in children and adolescents: midterm outcomes
url	https://dx.doi.org/10.1186/s12872-022-02757-9
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author2	Nobakhti, Mohammadjavad Naghshzan, Amir Amoozgar, Hamid Amirghofran, Ahmadali Ghasemzadeh, Bahram Nirooie, Elahe Mehdizadegan, Nima Mohammadi, Hamid Keshavarz, Kambiz
author2Str	Nobakhti, Mohammadjavad Naghshzan, Amir Amoozgar, Hamid Amirghofran, Ahmadali Ghasemzadeh, Bahram Nirooie, Elahe Mehdizadegan, Nima Mohammadi, Hamid Keshavarz, Kambiz
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up_date	2024-07-03T18:12:49.481Z
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