How Covid-19 changed the epidemiology of febrile urinary tract infections in children in the emergency department during the first outbreak

Background The first Covid-19 pandemic affected the epidemiology of several diseases. A general reduction in the emergency department (ED) accesses was observed during this period, both in adult and pediatric contexts. Methods This retrospective study was conducted on the behalf of the Italian Socie...
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Autor*in:	Cesca, Laura [verfasserIn] Conversano, Ester Vianello, Federica Alessandra Martelli, Laura Gualeni, Chiara Bassani, Francesca Brugnara, Milena Rubin, Giulia Parolin, Mattia Anselmi, Mauro Marchiori, Mara Vergine, Gianluca Miorin, Elisabetta Vidal, Enrico Milocco, Cristina Orsi, Cecilia Puccio, Giuseppe Peruzzi, Licia Montini, Giovanni Dall’Amico, Roberto

Format:	E-Artikel
Sprache:	Englisch

Erschienen:	2022

Schlagwörter:	Urinary tract infection Covid19 Diagnosis delay

Anmerkung:	© The Author(s) 2022

Übergeordnetes Werk:	Enthalten in: BMC pediatrics - London : BioMed Central, 2001, 22(2022), 1 vom: 15. Sept.
Übergeordnetes Werk:	volume:22 ; year:2022 ; number:1 ; day:15 ; month:09

Links:	Volltext

DOI / URN:	10.1186/s12887-022-03516-7

Katalog-ID:	SPR050995162

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520			\|a Background The first Covid-19 pandemic affected the epidemiology of several diseases. A general reduction in the emergency department (ED) accesses was observed during this period, both in adult and pediatric contexts. Methods This retrospective study was conducted on the behalf of the Italian Society of Pediatric Nephrology (SINePe) in 17 Italian pediatric EDs in March and April 2020, comparing them with data from the same periods in 2018 and 2019. The total number of pediatric (age 0–18 years) ED visits, the number of febrile urinary tract infection (UTI) diagnoses, and clinical and laboratory parameters were retrospectively collected. Results The total number of febrile UTI diagnoses was 339 (73 in 2020, 140 in 2019, and 126 in 2018). During the first Covid-19 pandemic, the total number of ED visits decreased by 75.1%, the total number of febrile UTI diagnoses by 45.1%, with an increase in the UTI diagnosis rate (+ 121.7%). The data collected revealed an increased rate of patients with two or more days of fever before admission (p = 0.02), a significant increase in hospitalization rate (+ 17.5%, p = 0.008) and also in values of C reactive protein (CRP) (p = 0.006). In 2020, intravenous antibiotics use was significantly higher than in 2018 and 2019 (+ 15%, p = 0.025). Urine cultures showed higher Pseudomonas aeruginosa and Enterococcus faecalis percentages and lower rates of Escherichia coli (p = 0.02). Conclusions The first wave of the Covid-19 pandemic had an essential impact on managing febrile UTIs in the ED, causing an absolute reduction of cases referring to the ED but with higher clinical severity. Children with febrile UTI were more severely ill than the previous two years, probably due to delayed access caused by the fear of potential hospital-acquired Sars-Cov-2 infection. The possible increase in consequent kidney scarring in this population should be considered.
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allfields	10.1186/s12887-022-03516-7 doi (DE-627)SPR050995162 (SPR)s12887-022-03516-7-e DE-627 ger DE-627 rakwb eng Cesca, Laura verfasserin aut How Covid-19 changed the epidemiology of febrile urinary tract infections in children in the emergency department during the first outbreak 2022 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier © The Author(s) 2022 Background The first Covid-19 pandemic affected the epidemiology of several diseases. A general reduction in the emergency department (ED) accesses was observed during this period, both in adult and pediatric contexts. Methods This retrospective study was conducted on the behalf of the Italian Society of Pediatric Nephrology (SINePe) in 17 Italian pediatric EDs in March and April 2020, comparing them with data from the same periods in 2018 and 2019. The total number of pediatric (age 0–18 years) ED visits, the number of febrile urinary tract infection (UTI) diagnoses, and clinical and laboratory parameters were retrospectively collected. Results The total number of febrile UTI diagnoses was 339 (73 in 2020, 140 in 2019, and 126 in 2018). During the first Covid-19 pandemic, the total number of ED visits decreased by 75.1%, the total number of febrile UTI diagnoses by 45.1%, with an increase in the UTI diagnosis rate (+ 121.7%). The data collected revealed an increased rate of patients with two or more days of fever before admission (p = 0.02), a significant increase in hospitalization rate (+ 17.5%, p = 0.008) and also in values of C reactive protein (CRP) (p = 0.006). In 2020, intravenous antibiotics use was significantly higher than in 2018 and 2019 (+ 15%, p = 0.025). Urine cultures showed higher Pseudomonas aeruginosa and Enterococcus faecalis percentages and lower rates of Escherichia coli (p = 0.02). Conclusions The first wave of the Covid-19 pandemic had an essential impact on managing febrile UTIs in the ED, causing an absolute reduction of cases referring to the ED but with higher clinical severity. Children with febrile UTI were more severely ill than the previous two years, probably due to delayed access caused by the fear of potential hospital-acquired Sars-Cov-2 infection. The possible increase in consequent kidney scarring in this population should be considered. Urinary tract infection (dpeaa)DE-He213 Covid19 (dpeaa)DE-He213 Diagnosis delay (dpeaa)DE-He213 Conversano, Ester (orcid)0000-0003-4317-8231 aut Vianello, Federica Alessandra aut Martelli, Laura aut Gualeni, Chiara aut Bassani, Francesca aut Brugnara, Milena aut Rubin, Giulia aut Parolin, Mattia aut Anselmi, Mauro aut Marchiori, Mara aut Vergine, Gianluca aut Miorin, Elisabetta aut Vidal, Enrico aut Milocco, Cristina aut Orsi, Cecilia aut Puccio, Giuseppe aut Peruzzi, Licia aut Montini, Giovanni aut Dall’Amico, Roberto aut Enthalten in BMC pediatrics London : BioMed Central, 2001 22(2022), 1 vom: 15. Sept. (DE-627)326643621 (DE-600)2041342-7 1471-2431 nnns volume:22 year:2022 number:1 day:15 month:09 https://dx.doi.org/10.1186/s12887-022-03516-7 kostenfrei Volltext GBV_USEFLAG_A SYSFLAG_A GBV_SPRINGER GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_2014 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 22 2022 1 15 09
spelling	10.1186/s12887-022-03516-7 doi (DE-627)SPR050995162 (SPR)s12887-022-03516-7-e DE-627 ger DE-627 rakwb eng Cesca, Laura verfasserin aut How Covid-19 changed the epidemiology of febrile urinary tract infections in children in the emergency department during the first outbreak 2022 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier © The Author(s) 2022 Background The first Covid-19 pandemic affected the epidemiology of several diseases. A general reduction in the emergency department (ED) accesses was observed during this period, both in adult and pediatric contexts. Methods This retrospective study was conducted on the behalf of the Italian Society of Pediatric Nephrology (SINePe) in 17 Italian pediatric EDs in March and April 2020, comparing them with data from the same periods in 2018 and 2019. The total number of pediatric (age 0–18 years) ED visits, the number of febrile urinary tract infection (UTI) diagnoses, and clinical and laboratory parameters were retrospectively collected. Results The total number of febrile UTI diagnoses was 339 (73 in 2020, 140 in 2019, and 126 in 2018). During the first Covid-19 pandemic, the total number of ED visits decreased by 75.1%, the total number of febrile UTI diagnoses by 45.1%, with an increase in the UTI diagnosis rate (+ 121.7%). The data collected revealed an increased rate of patients with two or more days of fever before admission (p = 0.02), a significant increase in hospitalization rate (+ 17.5%, p = 0.008) and also in values of C reactive protein (CRP) (p = 0.006). In 2020, intravenous antibiotics use was significantly higher than in 2018 and 2019 (+ 15%, p = 0.025). Urine cultures showed higher Pseudomonas aeruginosa and Enterococcus faecalis percentages and lower rates of Escherichia coli (p = 0.02). Conclusions The first wave of the Covid-19 pandemic had an essential impact on managing febrile UTIs in the ED, causing an absolute reduction of cases referring to the ED but with higher clinical severity. Children with febrile UTI were more severely ill than the previous two years, probably due to delayed access caused by the fear of potential hospital-acquired Sars-Cov-2 infection. The possible increase in consequent kidney scarring in this population should be considered. Urinary tract infection (dpeaa)DE-He213 Covid19 (dpeaa)DE-He213 Diagnosis delay (dpeaa)DE-He213 Conversano, Ester (orcid)0000-0003-4317-8231 aut Vianello, Federica Alessandra aut Martelli, Laura aut Gualeni, Chiara aut Bassani, Francesca aut Brugnara, Milena aut Rubin, Giulia aut Parolin, Mattia aut Anselmi, Mauro aut Marchiori, Mara aut Vergine, Gianluca aut Miorin, Elisabetta aut Vidal, Enrico aut Milocco, Cristina aut Orsi, Cecilia aut Puccio, Giuseppe aut Peruzzi, Licia aut Montini, Giovanni aut Dall’Amico, Roberto aut Enthalten in BMC pediatrics London : BioMed Central, 2001 22(2022), 1 vom: 15. Sept. (DE-627)326643621 (DE-600)2041342-7 1471-2431 nnns volume:22 year:2022 number:1 day:15 month:09 https://dx.doi.org/10.1186/s12887-022-03516-7 kostenfrei Volltext GBV_USEFLAG_A SYSFLAG_A GBV_SPRINGER GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_2014 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 22 2022 1 15 09
allfields_unstemmed	10.1186/s12887-022-03516-7 doi (DE-627)SPR050995162 (SPR)s12887-022-03516-7-e DE-627 ger DE-627 rakwb eng Cesca, Laura verfasserin aut How Covid-19 changed the epidemiology of febrile urinary tract infections in children in the emergency department during the first outbreak 2022 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier © The Author(s) 2022 Background The first Covid-19 pandemic affected the epidemiology of several diseases. A general reduction in the emergency department (ED) accesses was observed during this period, both in adult and pediatric contexts. Methods This retrospective study was conducted on the behalf of the Italian Society of Pediatric Nephrology (SINePe) in 17 Italian pediatric EDs in March and April 2020, comparing them with data from the same periods in 2018 and 2019. The total number of pediatric (age 0–18 years) ED visits, the number of febrile urinary tract infection (UTI) diagnoses, and clinical and laboratory parameters were retrospectively collected. Results The total number of febrile UTI diagnoses was 339 (73 in 2020, 140 in 2019, and 126 in 2018). During the first Covid-19 pandemic, the total number of ED visits decreased by 75.1%, the total number of febrile UTI diagnoses by 45.1%, with an increase in the UTI diagnosis rate (+ 121.7%). The data collected revealed an increased rate of patients with two or more days of fever before admission (p = 0.02), a significant increase in hospitalization rate (+ 17.5%, p = 0.008) and also in values of C reactive protein (CRP) (p = 0.006). In 2020, intravenous antibiotics use was significantly higher than in 2018 and 2019 (+ 15%, p = 0.025). Urine cultures showed higher Pseudomonas aeruginosa and Enterococcus faecalis percentages and lower rates of Escherichia coli (p = 0.02). Conclusions The first wave of the Covid-19 pandemic had an essential impact on managing febrile UTIs in the ED, causing an absolute reduction of cases referring to the ED but with higher clinical severity. Children with febrile UTI were more severely ill than the previous two years, probably due to delayed access caused by the fear of potential hospital-acquired Sars-Cov-2 infection. The possible increase in consequent kidney scarring in this population should be considered. Urinary tract infection (dpeaa)DE-He213 Covid19 (dpeaa)DE-He213 Diagnosis delay (dpeaa)DE-He213 Conversano, Ester (orcid)0000-0003-4317-8231 aut Vianello, Federica Alessandra aut Martelli, Laura aut Gualeni, Chiara aut Bassani, Francesca aut Brugnara, Milena aut Rubin, Giulia aut Parolin, Mattia aut Anselmi, Mauro aut Marchiori, Mara aut Vergine, Gianluca aut Miorin, Elisabetta aut Vidal, Enrico aut Milocco, Cristina aut Orsi, Cecilia aut Puccio, Giuseppe aut Peruzzi, Licia aut Montini, Giovanni aut Dall’Amico, Roberto aut Enthalten in BMC pediatrics London : BioMed Central, 2001 22(2022), 1 vom: 15. Sept. (DE-627)326643621 (DE-600)2041342-7 1471-2431 nnns volume:22 year:2022 number:1 day:15 month:09 https://dx.doi.org/10.1186/s12887-022-03516-7 kostenfrei Volltext GBV_USEFLAG_A SYSFLAG_A GBV_SPRINGER GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_2014 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 22 2022 1 15 09
allfieldsGer	10.1186/s12887-022-03516-7 doi (DE-627)SPR050995162 (SPR)s12887-022-03516-7-e DE-627 ger DE-627 rakwb eng Cesca, Laura verfasserin aut How Covid-19 changed the epidemiology of febrile urinary tract infections in children in the emergency department during the first outbreak 2022 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier © The Author(s) 2022 Background The first Covid-19 pandemic affected the epidemiology of several diseases. A general reduction in the emergency department (ED) accesses was observed during this period, both in adult and pediatric contexts. Methods This retrospective study was conducted on the behalf of the Italian Society of Pediatric Nephrology (SINePe) in 17 Italian pediatric EDs in March and April 2020, comparing them with data from the same periods in 2018 and 2019. The total number of pediatric (age 0–18 years) ED visits, the number of febrile urinary tract infection (UTI) diagnoses, and clinical and laboratory parameters were retrospectively collected. Results The total number of febrile UTI diagnoses was 339 (73 in 2020, 140 in 2019, and 126 in 2018). During the first Covid-19 pandemic, the total number of ED visits decreased by 75.1%, the total number of febrile UTI diagnoses by 45.1%, with an increase in the UTI diagnosis rate (+ 121.7%). The data collected revealed an increased rate of patients with two or more days of fever before admission (p = 0.02), a significant increase in hospitalization rate (+ 17.5%, p = 0.008) and also in values of C reactive protein (CRP) (p = 0.006). In 2020, intravenous antibiotics use was significantly higher than in 2018 and 2019 (+ 15%, p = 0.025). Urine cultures showed higher Pseudomonas aeruginosa and Enterococcus faecalis percentages and lower rates of Escherichia coli (p = 0.02). Conclusions The first wave of the Covid-19 pandemic had an essential impact on managing febrile UTIs in the ED, causing an absolute reduction of cases referring to the ED but with higher clinical severity. Children with febrile UTI were more severely ill than the previous two years, probably due to delayed access caused by the fear of potential hospital-acquired Sars-Cov-2 infection. The possible increase in consequent kidney scarring in this population should be considered. Urinary tract infection (dpeaa)DE-He213 Covid19 (dpeaa)DE-He213 Diagnosis delay (dpeaa)DE-He213 Conversano, Ester (orcid)0000-0003-4317-8231 aut Vianello, Federica Alessandra aut Martelli, Laura aut Gualeni, Chiara aut Bassani, Francesca aut Brugnara, Milena aut Rubin, Giulia aut Parolin, Mattia aut Anselmi, Mauro aut Marchiori, Mara aut Vergine, Gianluca aut Miorin, Elisabetta aut Vidal, Enrico aut Milocco, Cristina aut Orsi, Cecilia aut Puccio, Giuseppe aut Peruzzi, Licia aut Montini, Giovanni aut Dall’Amico, Roberto aut Enthalten in BMC pediatrics London : BioMed Central, 2001 22(2022), 1 vom: 15. Sept. (DE-627)326643621 (DE-600)2041342-7 1471-2431 nnns volume:22 year:2022 number:1 day:15 month:09 https://dx.doi.org/10.1186/s12887-022-03516-7 kostenfrei Volltext GBV_USEFLAG_A SYSFLAG_A GBV_SPRINGER GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_2014 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 22 2022 1 15 09
allfieldsSound	10.1186/s12887-022-03516-7 doi (DE-627)SPR050995162 (SPR)s12887-022-03516-7-e DE-627 ger DE-627 rakwb eng Cesca, Laura verfasserin aut How Covid-19 changed the epidemiology of febrile urinary tract infections in children in the emergency department during the first outbreak 2022 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier © The Author(s) 2022 Background The first Covid-19 pandemic affected the epidemiology of several diseases. A general reduction in the emergency department (ED) accesses was observed during this period, both in adult and pediatric contexts. Methods This retrospective study was conducted on the behalf of the Italian Society of Pediatric Nephrology (SINePe) in 17 Italian pediatric EDs in March and April 2020, comparing them with data from the same periods in 2018 and 2019. The total number of pediatric (age 0–18 years) ED visits, the number of febrile urinary tract infection (UTI) diagnoses, and clinical and laboratory parameters were retrospectively collected. Results The total number of febrile UTI diagnoses was 339 (73 in 2020, 140 in 2019, and 126 in 2018). During the first Covid-19 pandemic, the total number of ED visits decreased by 75.1%, the total number of febrile UTI diagnoses by 45.1%, with an increase in the UTI diagnosis rate (+ 121.7%). The data collected revealed an increased rate of patients with two or more days of fever before admission (p = 0.02), a significant increase in hospitalization rate (+ 17.5%, p = 0.008) and also in values of C reactive protein (CRP) (p = 0.006). In 2020, intravenous antibiotics use was significantly higher than in 2018 and 2019 (+ 15%, p = 0.025). Urine cultures showed higher Pseudomonas aeruginosa and Enterococcus faecalis percentages and lower rates of Escherichia coli (p = 0.02). Conclusions The first wave of the Covid-19 pandemic had an essential impact on managing febrile UTIs in the ED, causing an absolute reduction of cases referring to the ED but with higher clinical severity. Children with febrile UTI were more severely ill than the previous two years, probably due to delayed access caused by the fear of potential hospital-acquired Sars-Cov-2 infection. The possible increase in consequent kidney scarring in this population should be considered. Urinary tract infection (dpeaa)DE-He213 Covid19 (dpeaa)DE-He213 Diagnosis delay (dpeaa)DE-He213 Conversano, Ester (orcid)0000-0003-4317-8231 aut Vianello, Federica Alessandra aut Martelli, Laura aut Gualeni, Chiara aut Bassani, Francesca aut Brugnara, Milena aut Rubin, Giulia aut Parolin, Mattia aut Anselmi, Mauro aut Marchiori, Mara aut Vergine, Gianluca aut Miorin, Elisabetta aut Vidal, Enrico aut Milocco, Cristina aut Orsi, Cecilia aut Puccio, Giuseppe aut Peruzzi, Licia aut Montini, Giovanni aut Dall’Amico, Roberto aut Enthalten in BMC pediatrics London : BioMed Central, 2001 22(2022), 1 vom: 15. Sept. (DE-627)326643621 (DE-600)2041342-7 1471-2431 nnns volume:22 year:2022 number:1 day:15 month:09 https://dx.doi.org/10.1186/s12887-022-03516-7 kostenfrei Volltext GBV_USEFLAG_A SYSFLAG_A GBV_SPRINGER GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_2014 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 22 2022 1 15 09
language	English
source	Enthalten in BMC pediatrics 22(2022), 1 vom: 15. Sept. volume:22 year:2022 number:1 day:15 month:09
sourceStr	Enthalten in BMC pediatrics 22(2022), 1 vom: 15. Sept. volume:22 year:2022 number:1 day:15 month:09
format_phy_str_mv	Article
institution	findex.gbv.de
topic_facet	Urinary tract infection Covid19 Diagnosis delay
isfreeaccess_bool	true
container_title	BMC pediatrics
authorswithroles_txt_mv	Cesca, Laura @@aut@@ Conversano, Ester @@aut@@ Vianello, Federica Alessandra @@aut@@ Martelli, Laura @@aut@@ Gualeni, Chiara @@aut@@ Bassani, Francesca @@aut@@ Brugnara, Milena @@aut@@ Rubin, Giulia @@aut@@ Parolin, Mattia @@aut@@ Anselmi, Mauro @@aut@@ Marchiori, Mara @@aut@@ Vergine, Gianluca @@aut@@ Miorin, Elisabetta @@aut@@ Vidal, Enrico @@aut@@ Milocco, Cristina @@aut@@ Orsi, Cecilia @@aut@@ Puccio, Giuseppe @@aut@@ Peruzzi, Licia @@aut@@ Montini, Giovanni @@aut@@ Dall’Amico, Roberto @@aut@@
publishDateDaySort_date	2022-09-15T00:00:00Z
hierarchy_top_id	326643621
id	SPR050995162
language_de	englisch
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author	Cesca, Laura
spellingShingle	Cesca, Laura misc Urinary tract infection misc Covid19 misc Diagnosis delay How Covid-19 changed the epidemiology of febrile urinary tract infections in children in the emergency department during the first outbreak
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topic_title	How Covid-19 changed the epidemiology of febrile urinary tract infections in children in the emergency department during the first outbreak Urinary tract infection (dpeaa)DE-He213 Covid19 (dpeaa)DE-He213 Diagnosis delay (dpeaa)DE-He213
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title	How Covid-19 changed the epidemiology of febrile urinary tract infections in children in the emergency department during the first outbreak
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title_full	How Covid-19 changed the epidemiology of febrile urinary tract infections in children in the emergency department during the first outbreak
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author_browse	Cesca, Laura Conversano, Ester Vianello, Federica Alessandra Martelli, Laura Gualeni, Chiara Bassani, Francesca Brugnara, Milena Rubin, Giulia Parolin, Mattia Anselmi, Mauro Marchiori, Mara Vergine, Gianluca Miorin, Elisabetta Vidal, Enrico Milocco, Cristina Orsi, Cecilia Puccio, Giuseppe Peruzzi, Licia Montini, Giovanni Dall’Amico, Roberto
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title_sort	how covid-19 changed the epidemiology of febrile urinary tract infections in children in the emergency department during the first outbreak
title_auth	How Covid-19 changed the epidemiology of febrile urinary tract infections in children in the emergency department during the first outbreak
abstract	Background The first Covid-19 pandemic affected the epidemiology of several diseases. A general reduction in the emergency department (ED) accesses was observed during this period, both in adult and pediatric contexts. Methods This retrospective study was conducted on the behalf of the Italian Society of Pediatric Nephrology (SINePe) in 17 Italian pediatric EDs in March and April 2020, comparing them with data from the same periods in 2018 and 2019. The total number of pediatric (age 0–18 years) ED visits, the number of febrile urinary tract infection (UTI) diagnoses, and clinical and laboratory parameters were retrospectively collected. Results The total number of febrile UTI diagnoses was 339 (73 in 2020, 140 in 2019, and 126 in 2018). During the first Covid-19 pandemic, the total number of ED visits decreased by 75.1%, the total number of febrile UTI diagnoses by 45.1%, with an increase in the UTI diagnosis rate (+ 121.7%). The data collected revealed an increased rate of patients with two or more days of fever before admission (p = 0.02), a significant increase in hospitalization rate (+ 17.5%, p = 0.008) and also in values of C reactive protein (CRP) (p = 0.006). In 2020, intravenous antibiotics use was significantly higher than in 2018 and 2019 (+ 15%, p = 0.025). Urine cultures showed higher Pseudomonas aeruginosa and Enterococcus faecalis percentages and lower rates of Escherichia coli (p = 0.02). Conclusions The first wave of the Covid-19 pandemic had an essential impact on managing febrile UTIs in the ED, causing an absolute reduction of cases referring to the ED but with higher clinical severity. Children with febrile UTI were more severely ill than the previous two years, probably due to delayed access caused by the fear of potential hospital-acquired Sars-Cov-2 infection. The possible increase in consequent kidney scarring in this population should be considered. © The Author(s) 2022
abstractGer	Background The first Covid-19 pandemic affected the epidemiology of several diseases. A general reduction in the emergency department (ED) accesses was observed during this period, both in adult and pediatric contexts. Methods This retrospective study was conducted on the behalf of the Italian Society of Pediatric Nephrology (SINePe) in 17 Italian pediatric EDs in March and April 2020, comparing them with data from the same periods in 2018 and 2019. The total number of pediatric (age 0–18 years) ED visits, the number of febrile urinary tract infection (UTI) diagnoses, and clinical and laboratory parameters were retrospectively collected. Results The total number of febrile UTI diagnoses was 339 (73 in 2020, 140 in 2019, and 126 in 2018). During the first Covid-19 pandemic, the total number of ED visits decreased by 75.1%, the total number of febrile UTI diagnoses by 45.1%, with an increase in the UTI diagnosis rate (+ 121.7%). The data collected revealed an increased rate of patients with two or more days of fever before admission (p = 0.02), a significant increase in hospitalization rate (+ 17.5%, p = 0.008) and also in values of C reactive protein (CRP) (p = 0.006). In 2020, intravenous antibiotics use was significantly higher than in 2018 and 2019 (+ 15%, p = 0.025). Urine cultures showed higher Pseudomonas aeruginosa and Enterococcus faecalis percentages and lower rates of Escherichia coli (p = 0.02). Conclusions The first wave of the Covid-19 pandemic had an essential impact on managing febrile UTIs in the ED, causing an absolute reduction of cases referring to the ED but with higher clinical severity. Children with febrile UTI were more severely ill than the previous two years, probably due to delayed access caused by the fear of potential hospital-acquired Sars-Cov-2 infection. The possible increase in consequent kidney scarring in this population should be considered. © The Author(s) 2022
abstract_unstemmed	Background The first Covid-19 pandemic affected the epidemiology of several diseases. A general reduction in the emergency department (ED) accesses was observed during this period, both in adult and pediatric contexts. Methods This retrospective study was conducted on the behalf of the Italian Society of Pediatric Nephrology (SINePe) in 17 Italian pediatric EDs in March and April 2020, comparing them with data from the same periods in 2018 and 2019. The total number of pediatric (age 0–18 years) ED visits, the number of febrile urinary tract infection (UTI) diagnoses, and clinical and laboratory parameters were retrospectively collected. Results The total number of febrile UTI diagnoses was 339 (73 in 2020, 140 in 2019, and 126 in 2018). During the first Covid-19 pandemic, the total number of ED visits decreased by 75.1%, the total number of febrile UTI diagnoses by 45.1%, with an increase in the UTI diagnosis rate (+ 121.7%). The data collected revealed an increased rate of patients with two or more days of fever before admission (p = 0.02), a significant increase in hospitalization rate (+ 17.5%, p = 0.008) and also in values of C reactive protein (CRP) (p = 0.006). In 2020, intravenous antibiotics use was significantly higher than in 2018 and 2019 (+ 15%, p = 0.025). Urine cultures showed higher Pseudomonas aeruginosa and Enterococcus faecalis percentages and lower rates of Escherichia coli (p = 0.02). Conclusions The first wave of the Covid-19 pandemic had an essential impact on managing febrile UTIs in the ED, causing an absolute reduction of cases referring to the ED but with higher clinical severity. Children with febrile UTI were more severely ill than the previous two years, probably due to delayed access caused by the fear of potential hospital-acquired Sars-Cov-2 infection. The possible increase in consequent kidney scarring in this population should be considered. © The Author(s) 2022
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title_short	How Covid-19 changed the epidemiology of febrile urinary tract infections in children in the emergency department during the first outbreak
url	https://dx.doi.org/10.1186/s12887-022-03516-7
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author2	Conversano, Ester Vianello, Federica Alessandra Martelli, Laura Gualeni, Chiara Bassani, Francesca Brugnara, Milena Rubin, Giulia Parolin, Mattia Anselmi, Mauro Marchiori, Mara Vergine, Gianluca Miorin, Elisabetta Vidal, Enrico Milocco, Cristina Orsi, Cecilia Puccio, Giuseppe Peruzzi, Licia Montini, Giovanni Dall’Amico, Roberto
author2Str	Conversano, Ester Vianello, Federica Alessandra Martelli, Laura Gualeni, Chiara Bassani, Francesca Brugnara, Milena Rubin, Giulia Parolin, Mattia Anselmi, Mauro Marchiori, Mara Vergine, Gianluca Miorin, Elisabetta Vidal, Enrico Milocco, Cristina Orsi, Cecilia Puccio, Giuseppe Peruzzi, Licia Montini, Giovanni Dall’Amico, Roberto
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