Healthcare costs for hospitalized COVID-19 patients in a Japanese university hospital: a cross-sectional study

Background A health-economic evaluation related to COVID-19 is urgently needed to allocate healthcare resources efficiently; however, relevant medical cost data in Japan concerning COVID-19 are scarce. Methods This cross-sectional study investigated the healthcare cost for hospitalized COVID-19 pati...
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Autor*in:	Uno, Shunsuke [verfasserIn] Goto, Rei Honda, Kimiko Tokuda, Machiko Kamata, Hirofumi Chubachi, Shotaro Yamamoto, Ryo Sato, Yukio Homma, Koichiro Uchida, Sho Namkoong, Ho Uwamino, Yoshifumi Sasaki, Junichi Fukunaga, Koichi Hasegawa, Naoki

Format:	E-Artikel
Sprache:	Englisch

Erschienen:	2023

Schlagwörter:	COVID-19 Economic evaluation Healthcare costs Hospitalization Hospital length of stay

Anmerkung:	© The Author(s) 2023

Übergeordnetes Werk:	Enthalten in: Cost effectiveness and resource allocation - London : BioMed Central, 2003, 21(2023), 1 vom: 16. Juli
Übergeordnetes Werk:	volume:21 ; year:2023 ; number:1 ; day:16 ; month:07

Links:	Volltext

DOI / URN:	10.1186/s12962-023-00453-9

Katalog-ID:	SPR052271048

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520			\|a Background A health-economic evaluation related to COVID-19 is urgently needed to allocate healthcare resources efficiently; however, relevant medical cost data in Japan concerning COVID-19 are scarce. Methods This cross-sectional study investigated the healthcare cost for hospitalized COVID-19 patients in 2021 at Keio University Hospital. We calculated the healthcare costs during hospitalization using hospital claims data and investigated the variables significantly related to the healthcare cost with multivariable analysis. Results The median healthcare cost per patient for the analyzed 330 patients was Japanese yen (JPY) 1,304,431 (US dollars ~ 11,871) (interquartile range: JPY 968,349–1,954,093), and the median length of stay was 10 days. The median healthcare cost was JPY 798,810 for mild cases; JPY 1,113,680 for moderate I cases; JPY 1,643,909 for moderate II cases; and JPY 6,210,607 for severe cases. Healthcare costs increased by 4.0% for each additional day of hospitalization; 1.26 times for moderate I cases, 1.64 times for moderate II cases, and 1.84 times for severe cases compared to mild cases; and 2.05 times for cases involving ICU stay compared to those not staying in ICU. Conclusions We clarified the healthcare cost for hospitalized COVID-19 patients by severity in a Japanese university hospital. These costs contribute as inputs for forthcoming health economic evaluations for strategies for preventing and treating COVID-19.
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allfields	10.1186/s12962-023-00453-9 doi (DE-627)SPR052271048 (SPR)s12962-023-00453-9-e DE-627 ger DE-627 rakwb eng Uno, Shunsuke verfasserin aut Healthcare costs for hospitalized COVID-19 patients in a Japanese university hospital: a cross-sectional study 2023 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier © The Author(s) 2023 Background A health-economic evaluation related to COVID-19 is urgently needed to allocate healthcare resources efficiently; however, relevant medical cost data in Japan concerning COVID-19 are scarce. Methods This cross-sectional study investigated the healthcare cost for hospitalized COVID-19 patients in 2021 at Keio University Hospital. We calculated the healthcare costs during hospitalization using hospital claims data and investigated the variables significantly related to the healthcare cost with multivariable analysis. Results The median healthcare cost per patient for the analyzed 330 patients was Japanese yen (JPY) 1,304,431 (US dollars ~ 11,871) (interquartile range: JPY 968,349–1,954,093), and the median length of stay was 10 days. The median healthcare cost was JPY 798,810 for mild cases; JPY 1,113,680 for moderate I cases; JPY 1,643,909 for moderate II cases; and JPY 6,210,607 for severe cases. Healthcare costs increased by 4.0% for each additional day of hospitalization; 1.26 times for moderate I cases, 1.64 times for moderate II cases, and 1.84 times for severe cases compared to mild cases; and 2.05 times for cases involving ICU stay compared to those not staying in ICU. Conclusions We clarified the healthcare cost for hospitalized COVID-19 patients by severity in a Japanese university hospital. These costs contribute as inputs for forthcoming health economic evaluations for strategies for preventing and treating COVID-19. COVID-19 (dpeaa)DE-He213 Economic evaluation (dpeaa)DE-He213 Healthcare costs (dpeaa)DE-He213 Hospitalization (dpeaa)DE-He213 Hospital length of stay (dpeaa)DE-He213 Goto, Rei aut Honda, Kimiko aut Tokuda, Machiko aut Kamata, Hirofumi aut Chubachi, Shotaro aut Yamamoto, Ryo aut Sato, Yukio aut Homma, Koichiro aut Uchida, Sho aut Namkoong, Ho aut Uwamino, Yoshifumi aut Sasaki, Junichi aut Fukunaga, Koichi aut Hasegawa, Naoki aut Enthalten in Cost effectiveness and resource allocation London : BioMed Central, 2003 21(2023), 1 vom: 16. Juli (DE-627)369555570 (DE-600)2119372-1 1478-7547 nnns volume:21 year:2023 number:1 day:16 month:07 https://dx.doi.org/10.1186/s12962-023-00453-9 kostenfrei Volltext GBV_USEFLAG_A SYSFLAG_A GBV_SPRINGER GBV_ILN_11 GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_2003 GBV_ILN_2005 GBV_ILN_2009 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2055 GBV_ILN_2111 GBV_ILN_2129 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4046 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 21 2023 1 16 07
spelling	10.1186/s12962-023-00453-9 doi (DE-627)SPR052271048 (SPR)s12962-023-00453-9-e DE-627 ger DE-627 rakwb eng Uno, Shunsuke verfasserin aut Healthcare costs for hospitalized COVID-19 patients in a Japanese university hospital: a cross-sectional study 2023 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier © The Author(s) 2023 Background A health-economic evaluation related to COVID-19 is urgently needed to allocate healthcare resources efficiently; however, relevant medical cost data in Japan concerning COVID-19 are scarce. Methods This cross-sectional study investigated the healthcare cost for hospitalized COVID-19 patients in 2021 at Keio University Hospital. We calculated the healthcare costs during hospitalization using hospital claims data and investigated the variables significantly related to the healthcare cost with multivariable analysis. Results The median healthcare cost per patient for the analyzed 330 patients was Japanese yen (JPY) 1,304,431 (US dollars ~ 11,871) (interquartile range: JPY 968,349–1,954,093), and the median length of stay was 10 days. The median healthcare cost was JPY 798,810 for mild cases; JPY 1,113,680 for moderate I cases; JPY 1,643,909 for moderate II cases; and JPY 6,210,607 for severe cases. Healthcare costs increased by 4.0% for each additional day of hospitalization; 1.26 times for moderate I cases, 1.64 times for moderate II cases, and 1.84 times for severe cases compared to mild cases; and 2.05 times for cases involving ICU stay compared to those not staying in ICU. Conclusions We clarified the healthcare cost for hospitalized COVID-19 patients by severity in a Japanese university hospital. These costs contribute as inputs for forthcoming health economic evaluations for strategies for preventing and treating COVID-19. COVID-19 (dpeaa)DE-He213 Economic evaluation (dpeaa)DE-He213 Healthcare costs (dpeaa)DE-He213 Hospitalization (dpeaa)DE-He213 Hospital length of stay (dpeaa)DE-He213 Goto, Rei aut Honda, Kimiko aut Tokuda, Machiko aut Kamata, Hirofumi aut Chubachi, Shotaro aut Yamamoto, Ryo aut Sato, Yukio aut Homma, Koichiro aut Uchida, Sho aut Namkoong, Ho aut Uwamino, Yoshifumi aut Sasaki, Junichi aut Fukunaga, Koichi aut Hasegawa, Naoki aut Enthalten in Cost effectiveness and resource allocation London : BioMed Central, 2003 21(2023), 1 vom: 16. Juli (DE-627)369555570 (DE-600)2119372-1 1478-7547 nnns volume:21 year:2023 number:1 day:16 month:07 https://dx.doi.org/10.1186/s12962-023-00453-9 kostenfrei Volltext GBV_USEFLAG_A SYSFLAG_A GBV_SPRINGER GBV_ILN_11 GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_2003 GBV_ILN_2005 GBV_ILN_2009 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2055 GBV_ILN_2111 GBV_ILN_2129 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4046 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 21 2023 1 16 07
allfields_unstemmed	10.1186/s12962-023-00453-9 doi (DE-627)SPR052271048 (SPR)s12962-023-00453-9-e DE-627 ger DE-627 rakwb eng Uno, Shunsuke verfasserin aut Healthcare costs for hospitalized COVID-19 patients in a Japanese university hospital: a cross-sectional study 2023 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier © The Author(s) 2023 Background A health-economic evaluation related to COVID-19 is urgently needed to allocate healthcare resources efficiently; however, relevant medical cost data in Japan concerning COVID-19 are scarce. Methods This cross-sectional study investigated the healthcare cost for hospitalized COVID-19 patients in 2021 at Keio University Hospital. We calculated the healthcare costs during hospitalization using hospital claims data and investigated the variables significantly related to the healthcare cost with multivariable analysis. Results The median healthcare cost per patient for the analyzed 330 patients was Japanese yen (JPY) 1,304,431 (US dollars ~ 11,871) (interquartile range: JPY 968,349–1,954,093), and the median length of stay was 10 days. The median healthcare cost was JPY 798,810 for mild cases; JPY 1,113,680 for moderate I cases; JPY 1,643,909 for moderate II cases; and JPY 6,210,607 for severe cases. Healthcare costs increased by 4.0% for each additional day of hospitalization; 1.26 times for moderate I cases, 1.64 times for moderate II cases, and 1.84 times for severe cases compared to mild cases; and 2.05 times for cases involving ICU stay compared to those not staying in ICU. Conclusions We clarified the healthcare cost for hospitalized COVID-19 patients by severity in a Japanese university hospital. These costs contribute as inputs for forthcoming health economic evaluations for strategies for preventing and treating COVID-19. COVID-19 (dpeaa)DE-He213 Economic evaluation (dpeaa)DE-He213 Healthcare costs (dpeaa)DE-He213 Hospitalization (dpeaa)DE-He213 Hospital length of stay (dpeaa)DE-He213 Goto, Rei aut Honda, Kimiko aut Tokuda, Machiko aut Kamata, Hirofumi aut Chubachi, Shotaro aut Yamamoto, Ryo aut Sato, Yukio aut Homma, Koichiro aut Uchida, Sho aut Namkoong, Ho aut Uwamino, Yoshifumi aut Sasaki, Junichi aut Fukunaga, Koichi aut Hasegawa, Naoki aut Enthalten in Cost effectiveness and resource allocation London : BioMed Central, 2003 21(2023), 1 vom: 16. Juli (DE-627)369555570 (DE-600)2119372-1 1478-7547 nnns volume:21 year:2023 number:1 day:16 month:07 https://dx.doi.org/10.1186/s12962-023-00453-9 kostenfrei Volltext GBV_USEFLAG_A SYSFLAG_A GBV_SPRINGER GBV_ILN_11 GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_2003 GBV_ILN_2005 GBV_ILN_2009 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2055 GBV_ILN_2111 GBV_ILN_2129 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4046 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 21 2023 1 16 07
allfieldsGer	10.1186/s12962-023-00453-9 doi (DE-627)SPR052271048 (SPR)s12962-023-00453-9-e DE-627 ger DE-627 rakwb eng Uno, Shunsuke verfasserin aut Healthcare costs for hospitalized COVID-19 patients in a Japanese university hospital: a cross-sectional study 2023 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier © The Author(s) 2023 Background A health-economic evaluation related to COVID-19 is urgently needed to allocate healthcare resources efficiently; however, relevant medical cost data in Japan concerning COVID-19 are scarce. Methods This cross-sectional study investigated the healthcare cost for hospitalized COVID-19 patients in 2021 at Keio University Hospital. We calculated the healthcare costs during hospitalization using hospital claims data and investigated the variables significantly related to the healthcare cost with multivariable analysis. Results The median healthcare cost per patient for the analyzed 330 patients was Japanese yen (JPY) 1,304,431 (US dollars ~ 11,871) (interquartile range: JPY 968,349–1,954,093), and the median length of stay was 10 days. The median healthcare cost was JPY 798,810 for mild cases; JPY 1,113,680 for moderate I cases; JPY 1,643,909 for moderate II cases; and JPY 6,210,607 for severe cases. Healthcare costs increased by 4.0% for each additional day of hospitalization; 1.26 times for moderate I cases, 1.64 times for moderate II cases, and 1.84 times for severe cases compared to mild cases; and 2.05 times for cases involving ICU stay compared to those not staying in ICU. Conclusions We clarified the healthcare cost for hospitalized COVID-19 patients by severity in a Japanese university hospital. These costs contribute as inputs for forthcoming health economic evaluations for strategies for preventing and treating COVID-19. COVID-19 (dpeaa)DE-He213 Economic evaluation (dpeaa)DE-He213 Healthcare costs (dpeaa)DE-He213 Hospitalization (dpeaa)DE-He213 Hospital length of stay (dpeaa)DE-He213 Goto, Rei aut Honda, Kimiko aut Tokuda, Machiko aut Kamata, Hirofumi aut Chubachi, Shotaro aut Yamamoto, Ryo aut Sato, Yukio aut Homma, Koichiro aut Uchida, Sho aut Namkoong, Ho aut Uwamino, Yoshifumi aut Sasaki, Junichi aut Fukunaga, Koichi aut Hasegawa, Naoki aut Enthalten in Cost effectiveness and resource allocation London : BioMed Central, 2003 21(2023), 1 vom: 16. Juli (DE-627)369555570 (DE-600)2119372-1 1478-7547 nnns volume:21 year:2023 number:1 day:16 month:07 https://dx.doi.org/10.1186/s12962-023-00453-9 kostenfrei Volltext GBV_USEFLAG_A SYSFLAG_A GBV_SPRINGER GBV_ILN_11 GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_2003 GBV_ILN_2005 GBV_ILN_2009 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2055 GBV_ILN_2111 GBV_ILN_2129 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4046 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 21 2023 1 16 07
allfieldsSound	10.1186/s12962-023-00453-9 doi (DE-627)SPR052271048 (SPR)s12962-023-00453-9-e DE-627 ger DE-627 rakwb eng Uno, Shunsuke verfasserin aut Healthcare costs for hospitalized COVID-19 patients in a Japanese university hospital: a cross-sectional study 2023 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier © The Author(s) 2023 Background A health-economic evaluation related to COVID-19 is urgently needed to allocate healthcare resources efficiently; however, relevant medical cost data in Japan concerning COVID-19 are scarce. Methods This cross-sectional study investigated the healthcare cost for hospitalized COVID-19 patients in 2021 at Keio University Hospital. We calculated the healthcare costs during hospitalization using hospital claims data and investigated the variables significantly related to the healthcare cost with multivariable analysis. Results The median healthcare cost per patient for the analyzed 330 patients was Japanese yen (JPY) 1,304,431 (US dollars ~ 11,871) (interquartile range: JPY 968,349–1,954,093), and the median length of stay was 10 days. The median healthcare cost was JPY 798,810 for mild cases; JPY 1,113,680 for moderate I cases; JPY 1,643,909 for moderate II cases; and JPY 6,210,607 for severe cases. Healthcare costs increased by 4.0% for each additional day of hospitalization; 1.26 times for moderate I cases, 1.64 times for moderate II cases, and 1.84 times for severe cases compared to mild cases; and 2.05 times for cases involving ICU stay compared to those not staying in ICU. Conclusions We clarified the healthcare cost for hospitalized COVID-19 patients by severity in a Japanese university hospital. These costs contribute as inputs for forthcoming health economic evaluations for strategies for preventing and treating COVID-19. COVID-19 (dpeaa)DE-He213 Economic evaluation (dpeaa)DE-He213 Healthcare costs (dpeaa)DE-He213 Hospitalization (dpeaa)DE-He213 Hospital length of stay (dpeaa)DE-He213 Goto, Rei aut Honda, Kimiko aut Tokuda, Machiko aut Kamata, Hirofumi aut Chubachi, Shotaro aut Yamamoto, Ryo aut Sato, Yukio aut Homma, Koichiro aut Uchida, Sho aut Namkoong, Ho aut Uwamino, Yoshifumi aut Sasaki, Junichi aut Fukunaga, Koichi aut Hasegawa, Naoki aut Enthalten in Cost effectiveness and resource allocation London : BioMed Central, 2003 21(2023), 1 vom: 16. Juli (DE-627)369555570 (DE-600)2119372-1 1478-7547 nnns volume:21 year:2023 number:1 day:16 month:07 https://dx.doi.org/10.1186/s12962-023-00453-9 kostenfrei Volltext GBV_USEFLAG_A SYSFLAG_A GBV_SPRINGER GBV_ILN_11 GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_2003 GBV_ILN_2005 GBV_ILN_2009 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2055 GBV_ILN_2111 GBV_ILN_2129 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4046 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 21 2023 1 16 07
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author	Uno, Shunsuke
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topic_title	Healthcare costs for hospitalized COVID-19 patients in a Japanese university hospital: a cross-sectional study COVID-19 (dpeaa)DE-He213 Economic evaluation (dpeaa)DE-He213 Healthcare costs (dpeaa)DE-He213 Hospitalization (dpeaa)DE-He213 Hospital length of stay (dpeaa)DE-He213
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title_full	Healthcare costs for hospitalized COVID-19 patients in a Japanese university hospital: a cross-sectional study
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author_browse	Uno, Shunsuke Goto, Rei Honda, Kimiko Tokuda, Machiko Kamata, Hirofumi Chubachi, Shotaro Yamamoto, Ryo Sato, Yukio Homma, Koichiro Uchida, Sho Namkoong, Ho Uwamino, Yoshifumi Sasaki, Junichi Fukunaga, Koichi Hasegawa, Naoki
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title_sort	healthcare costs for hospitalized covid-19 patients in a japanese university hospital: a cross-sectional study
title_auth	Healthcare costs for hospitalized COVID-19 patients in a Japanese university hospital: a cross-sectional study
abstract	Background A health-economic evaluation related to COVID-19 is urgently needed to allocate healthcare resources efficiently; however, relevant medical cost data in Japan concerning COVID-19 are scarce. Methods This cross-sectional study investigated the healthcare cost for hospitalized COVID-19 patients in 2021 at Keio University Hospital. We calculated the healthcare costs during hospitalization using hospital claims data and investigated the variables significantly related to the healthcare cost with multivariable analysis. Results The median healthcare cost per patient for the analyzed 330 patients was Japanese yen (JPY) 1,304,431 (US dollars ~ 11,871) (interquartile range: JPY 968,349–1,954,093), and the median length of stay was 10 days. The median healthcare cost was JPY 798,810 for mild cases; JPY 1,113,680 for moderate I cases; JPY 1,643,909 for moderate II cases; and JPY 6,210,607 for severe cases. Healthcare costs increased by 4.0% for each additional day of hospitalization; 1.26 times for moderate I cases, 1.64 times for moderate II cases, and 1.84 times for severe cases compared to mild cases; and 2.05 times for cases involving ICU stay compared to those not staying in ICU. Conclusions We clarified the healthcare cost for hospitalized COVID-19 patients by severity in a Japanese university hospital. These costs contribute as inputs for forthcoming health economic evaluations for strategies for preventing and treating COVID-19. © The Author(s) 2023
abstractGer	Background A health-economic evaluation related to COVID-19 is urgently needed to allocate healthcare resources efficiently; however, relevant medical cost data in Japan concerning COVID-19 are scarce. Methods This cross-sectional study investigated the healthcare cost for hospitalized COVID-19 patients in 2021 at Keio University Hospital. We calculated the healthcare costs during hospitalization using hospital claims data and investigated the variables significantly related to the healthcare cost with multivariable analysis. Results The median healthcare cost per patient for the analyzed 330 patients was Japanese yen (JPY) 1,304,431 (US dollars ~ 11,871) (interquartile range: JPY 968,349–1,954,093), and the median length of stay was 10 days. The median healthcare cost was JPY 798,810 for mild cases; JPY 1,113,680 for moderate I cases; JPY 1,643,909 for moderate II cases; and JPY 6,210,607 for severe cases. Healthcare costs increased by 4.0% for each additional day of hospitalization; 1.26 times for moderate I cases, 1.64 times for moderate II cases, and 1.84 times for severe cases compared to mild cases; and 2.05 times for cases involving ICU stay compared to those not staying in ICU. Conclusions We clarified the healthcare cost for hospitalized COVID-19 patients by severity in a Japanese university hospital. These costs contribute as inputs for forthcoming health economic evaluations for strategies for preventing and treating COVID-19. © The Author(s) 2023
abstract_unstemmed	Background A health-economic evaluation related to COVID-19 is urgently needed to allocate healthcare resources efficiently; however, relevant medical cost data in Japan concerning COVID-19 are scarce. Methods This cross-sectional study investigated the healthcare cost for hospitalized COVID-19 patients in 2021 at Keio University Hospital. We calculated the healthcare costs during hospitalization using hospital claims data and investigated the variables significantly related to the healthcare cost with multivariable analysis. Results The median healthcare cost per patient for the analyzed 330 patients was Japanese yen (JPY) 1,304,431 (US dollars ~ 11,871) (interquartile range: JPY 968,349–1,954,093), and the median length of stay was 10 days. The median healthcare cost was JPY 798,810 for mild cases; JPY 1,113,680 for moderate I cases; JPY 1,643,909 for moderate II cases; and JPY 6,210,607 for severe cases. Healthcare costs increased by 4.0% for each additional day of hospitalization; 1.26 times for moderate I cases, 1.64 times for moderate II cases, and 1.84 times for severe cases compared to mild cases; and 2.05 times for cases involving ICU stay compared to those not staying in ICU. Conclusions We clarified the healthcare cost for hospitalized COVID-19 patients by severity in a Japanese university hospital. These costs contribute as inputs for forthcoming health economic evaluations for strategies for preventing and treating COVID-19. © The Author(s) 2023
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title_short	Healthcare costs for hospitalized COVID-19 patients in a Japanese university hospital: a cross-sectional study
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author2	Goto, Rei Honda, Kimiko Tokuda, Machiko Kamata, Hirofumi Chubachi, Shotaro Yamamoto, Ryo Sato, Yukio Homma, Koichiro Uchida, Sho Namkoong, Ho Uwamino, Yoshifumi Sasaki, Junichi Fukunaga, Koichi Hasegawa, Naoki
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Methods This cross-sectional study investigated the healthcare cost for hospitalized COVID-19 patients in 2021 at Keio University Hospital. We calculated the healthcare costs during hospitalization using hospital claims data and investigated the variables significantly related to the healthcare cost with multivariable analysis. Results The median healthcare cost per patient for the analyzed 330 patients was Japanese yen (JPY) 1,304,431 (US dollars ~ 11,871) (interquartile range: JPY 968,349–1,954,093), and the median length of stay was 10 days. The median healthcare cost was JPY 798,810 for mild cases; JPY 1,113,680 for moderate I cases; JPY 1,643,909 for moderate II cases; and JPY 6,210,607 for severe cases. Healthcare costs increased by 4.0% for each additional day of hospitalization; 1.26 times for moderate I cases, 1.64 times for moderate II cases, and 1.84 times for severe cases compared to mild cases; and 2.05 times for cases involving ICU stay compared to those not staying in ICU. Conclusions We clarified the healthcare cost for hospitalized COVID-19 patients by severity in a Japanese university hospital. 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Healthcare costs for hospitalized COVID-19 patients in a Japanese university hospital: a cross-sectional study

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