AWARE A novel web application to rapidly assess cardiovascular risk in type 2 diabetes mellitus
Aim To describe the development of the AWARE App, a novel web application for the rapid assessment of cardiovascular risk in Type 2 Diabetes Mellitus (T2DM) patients. We also tested the feasibility of using this App in clinical practice. Methods Based on 2019 European Society of Cardiology/European...
Ausführliche Beschreibung
Gespeichert in:
| Autor*in: |
Berra, Cesare [verfasserIn] |
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| Format: |
E-Artikel |
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| Sprache: |
Englisch |
| Erschienen: |
2023 |
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| Schlagwörter: |
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| Anmerkung: |
© The Author(s) 2023 |
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| Übergeordnetes Werk: |
Enthalten in: Acta diabetologica - Mailand : Springer, 1964, 60(2023), 9 vom: 04. Juni, Seite 1257-1266 |
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| Übergeordnetes Werk: |
volume:60 ; year:2023 ; number:9 ; day:04 ; month:06 ; pages:1257-1266 |
| Links: |
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| DOI / URN: |
10.1007/s00592-023-02115-x |
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| Katalog-ID: |
SPR052315479 |
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| 100 | 1 | |a Berra, Cesare |e verfasserin |0 (orcid)0000-0001-8431-8160 |4 aut | |
| 245 | 1 | 0 | |a AWARE A novel web application to rapidly assess cardiovascular risk in type 2 diabetes mellitus |
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| 520 | |a Aim To describe the development of the AWARE App, a novel web application for the rapid assessment of cardiovascular risk in Type 2 Diabetes Mellitus (T2DM) patients. We also tested the feasibility of using this App in clinical practice. Methods Based on 2019 European Society of Cardiology/European Association for the Study of Diabetes criteria for cardiovascular risk stratification in T2DM, the AWARE App classifies patients into very high ($ VH_{CVR} $), high ($ H_{CVR} $) and moderate ($ M_{CVR} $) cardiovascular risk categories. In this retrospective clinical study, we employed the App to assess the cardiovascular risk of T2DM patients, while also collecting data about current glycaemic control and pharmacological treatment. Results 2243 T2DM consecutive patients were evaluated. 72.2% of the patients were $ VH_{CVR} $, 8.9% were $ H_{CVR} $, 0.8% were $ M_{CVR} $ while 18.2% did not fit into any of the risk categories and were classified as “moderate-to-high” ($ MH_{CVR} $). Compared with the other groups, patients with $ VH_{CVD} $ were more frequently ≥ 65 years old (68.9%), with a longer disease duration (≥ 10 years [56.8%]), a history of cardiovascular disease (41.4%), organ damage (35.5%) and a higher numbers of cardiovascular risk factors. Patients with $ MH_{CVD} $ generally had disease duration < 10 years (96%), younger age (50–60 years [55%]), no history of cardiovascular disease, no organ damage, and 1–2 cardiovascular risk factors (89%). Novel drugs such as Glucagon Like Peptyde 1 Receptor Agonists or Sodium-Glucose Linked Transporter 2 inhibitors were prescribed only to 26.3% of the patients with $ VH_{CVR} $ and to 24.7% of those with $ H_{CVR} $. Glycaemic control was unsatisfactory in this patients population (HbA1c 7.5 ± 3.4% [58.7 ± 13.4 mmol/mol]). Conclusions The AWARE App proved to be a practical tool for cardiovascular risk stratification of T2DM patients in real-world clinical practice. | ||
| 650 | 4 | |a Type 2 diabetes mellitus |7 (dpeaa)DE-He213 | |
| 650 | 4 | |a Cardiovascular risk |7 (dpeaa)DE-He213 | |
| 650 | 4 | |a Digital tools |7 (dpeaa)DE-He213 | |
| 650 | 4 | |a Glucagon like peptide 1 receptor agonists |7 (dpeaa)DE-He213 | |
| 650 | 4 | |a Sodium-glucose co-transporter-2 inhibitors |7 (dpeaa)DE-He213 | |
| 700 | 1 | |a Manfrini, Roberto |4 aut | |
| 700 | 1 | |a Mirani, Marco |4 aut | |
| 700 | 1 | |a Bucciarelli, Loredana |4 aut | |
| 700 | 1 | |a Zakaria, Ahmed S. |4 aut | |
| 700 | 1 | |a Piccini, Sara |4 aut | |
| 700 | 1 | |a Ghelardi, Renata |4 aut | |
| 700 | 1 | |a Lunati, Maria Elena |4 aut | |
| 700 | 1 | |a Rodovalho, Sylka |4 aut | |
| 700 | 1 | |a Bifari, Francesco |4 aut | |
| 700 | 1 | |a Fiorina, Paolo |4 aut | |
| 700 | 1 | |a Folli, Franco |4 aut | |
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10.1007/s00592-023-02115-x doi (DE-627)SPR052315479 (SPR)s00592-023-02115-x-e DE-627 ger DE-627 rakwb eng Berra, Cesare verfasserin (orcid)0000-0001-8431-8160 aut AWARE A novel web application to rapidly assess cardiovascular risk in type 2 diabetes mellitus 2023 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier © The Author(s) 2023 Aim To describe the development of the AWARE App, a novel web application for the rapid assessment of cardiovascular risk in Type 2 Diabetes Mellitus (T2DM) patients. We also tested the feasibility of using this App in clinical practice. Methods Based on 2019 European Society of Cardiology/European Association for the Study of Diabetes criteria for cardiovascular risk stratification in T2DM, the AWARE App classifies patients into very high ($ VH_{CVR} $), high ($ H_{CVR} $) and moderate ($ M_{CVR} $) cardiovascular risk categories. In this retrospective clinical study, we employed the App to assess the cardiovascular risk of T2DM patients, while also collecting data about current glycaemic control and pharmacological treatment. Results 2243 T2DM consecutive patients were evaluated. 72.2% of the patients were $ VH_{CVR} $, 8.9% were $ H_{CVR} $, 0.8% were $ M_{CVR} $ while 18.2% did not fit into any of the risk categories and were classified as “moderate-to-high” ($ MH_{CVR} $). Compared with the other groups, patients with $ VH_{CVD} $ were more frequently ≥ 65 years old (68.9%), with a longer disease duration (≥ 10 years [56.8%]), a history of cardiovascular disease (41.4%), organ damage (35.5%) and a higher numbers of cardiovascular risk factors. Patients with $ MH_{CVD} $ generally had disease duration < 10 years (96%), younger age (50–60 years [55%]), no history of cardiovascular disease, no organ damage, and 1–2 cardiovascular risk factors (89%). Novel drugs such as Glucagon Like Peptyde 1 Receptor Agonists or Sodium-Glucose Linked Transporter 2 inhibitors were prescribed only to 26.3% of the patients with $ VH_{CVR} $ and to 24.7% of those with $ H_{CVR} $. Glycaemic control was unsatisfactory in this patients population (HbA1c 7.5 ± 3.4% [58.7 ± 13.4 mmol/mol]). Conclusions The AWARE App proved to be a practical tool for cardiovascular risk stratification of T2DM patients in real-world clinical practice. Type 2 diabetes mellitus (dpeaa)DE-He213 Cardiovascular risk (dpeaa)DE-He213 Digital tools (dpeaa)DE-He213 Glucagon like peptide 1 receptor agonists (dpeaa)DE-He213 Sodium-glucose co-transporter-2 inhibitors (dpeaa)DE-He213 Manfrini, Roberto aut Mirani, Marco aut Bucciarelli, Loredana aut Zakaria, Ahmed S. aut Piccini, Sara aut Ghelardi, Renata aut Lunati, Maria Elena aut Rodovalho, Sylka aut Bifari, Francesco aut Fiorina, Paolo aut Folli, Franco aut Enthalten in Acta diabetologica Mailand : Springer, 1964 60(2023), 9 vom: 04. Juni, Seite 1257-1266 (DE-627)266886469 (DE-600)1468518-8 1432-5233 nnns volume:60 year:2023 number:9 day:04 month:06 pages:1257-1266 https://dx.doi.org/10.1007/s00592-023-02115-x kostenfrei Volltext GBV_USEFLAG_A SYSFLAG_A GBV_SPRINGER GBV_ILN_11 GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_32 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_69 GBV_ILN_70 GBV_ILN_73 GBV_ILN_74 GBV_ILN_90 GBV_ILN_95 GBV_ILN_100 GBV_ILN_101 GBV_ILN_105 GBV_ILN_110 GBV_ILN_120 GBV_ILN_138 GBV_ILN_150 GBV_ILN_151 GBV_ILN_152 GBV_ILN_161 GBV_ILN_170 GBV_ILN_171 GBV_ILN_187 GBV_ILN_213 GBV_ILN_224 GBV_ILN_230 GBV_ILN_250 GBV_ILN_267 GBV_ILN_281 GBV_ILN_285 GBV_ILN_293 GBV_ILN_370 GBV_ILN_602 GBV_ILN_636 GBV_ILN_702 GBV_ILN_711 GBV_ILN_2001 GBV_ILN_2003 GBV_ILN_2004 GBV_ILN_2005 GBV_ILN_2006 GBV_ILN_2007 GBV_ILN_2008 GBV_ILN_2009 GBV_ILN_2010 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2015 GBV_ILN_2020 GBV_ILN_2021 GBV_ILN_2025 GBV_ILN_2026 GBV_ILN_2027 GBV_ILN_2031 GBV_ILN_2034 GBV_ILN_2037 GBV_ILN_2038 GBV_ILN_2039 GBV_ILN_2044 GBV_ILN_2048 GBV_ILN_2049 GBV_ILN_2050 GBV_ILN_2055 GBV_ILN_2056 GBV_ILN_2057 GBV_ILN_2059 GBV_ILN_2061 GBV_ILN_2064 GBV_ILN_2065 GBV_ILN_2068 GBV_ILN_2088 GBV_ILN_2093 GBV_ILN_2106 GBV_ILN_2107 GBV_ILN_2110 GBV_ILN_2111 GBV_ILN_2112 GBV_ILN_2113 GBV_ILN_2118 GBV_ILN_2129 GBV_ILN_2143 GBV_ILN_2144 GBV_ILN_2147 GBV_ILN_2148 GBV_ILN_2152 GBV_ILN_2153 GBV_ILN_2188 GBV_ILN_2190 GBV_ILN_2232 GBV_ILN_2336 GBV_ILN_2446 GBV_ILN_2470 GBV_ILN_2472 GBV_ILN_2507 GBV_ILN_2522 GBV_ILN_2548 GBV_ILN_4035 GBV_ILN_4037 GBV_ILN_4046 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4242 GBV_ILN_4246 GBV_ILN_4249 GBV_ILN_4251 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4326 GBV_ILN_4328 GBV_ILN_4333 GBV_ILN_4334 GBV_ILN_4335 GBV_ILN_4336 GBV_ILN_4338 GBV_ILN_4393 GBV_ILN_4700 AR 60 2023 9 04 06 1257-1266 |
| spelling |
10.1007/s00592-023-02115-x doi (DE-627)SPR052315479 (SPR)s00592-023-02115-x-e DE-627 ger DE-627 rakwb eng Berra, Cesare verfasserin (orcid)0000-0001-8431-8160 aut AWARE A novel web application to rapidly assess cardiovascular risk in type 2 diabetes mellitus 2023 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier © The Author(s) 2023 Aim To describe the development of the AWARE App, a novel web application for the rapid assessment of cardiovascular risk in Type 2 Diabetes Mellitus (T2DM) patients. We also tested the feasibility of using this App in clinical practice. Methods Based on 2019 European Society of Cardiology/European Association for the Study of Diabetes criteria for cardiovascular risk stratification in T2DM, the AWARE App classifies patients into very high ($ VH_{CVR} $), high ($ H_{CVR} $) and moderate ($ M_{CVR} $) cardiovascular risk categories. In this retrospective clinical study, we employed the App to assess the cardiovascular risk of T2DM patients, while also collecting data about current glycaemic control and pharmacological treatment. Results 2243 T2DM consecutive patients were evaluated. 72.2% of the patients were $ VH_{CVR} $, 8.9% were $ H_{CVR} $, 0.8% were $ M_{CVR} $ while 18.2% did not fit into any of the risk categories and were classified as “moderate-to-high” ($ MH_{CVR} $). Compared with the other groups, patients with $ VH_{CVD} $ were more frequently ≥ 65 years old (68.9%), with a longer disease duration (≥ 10 years [56.8%]), a history of cardiovascular disease (41.4%), organ damage (35.5%) and a higher numbers of cardiovascular risk factors. Patients with $ MH_{CVD} $ generally had disease duration < 10 years (96%), younger age (50–60 years [55%]), no history of cardiovascular disease, no organ damage, and 1–2 cardiovascular risk factors (89%). Novel drugs such as Glucagon Like Peptyde 1 Receptor Agonists or Sodium-Glucose Linked Transporter 2 inhibitors were prescribed only to 26.3% of the patients with $ VH_{CVR} $ and to 24.7% of those with $ H_{CVR} $. Glycaemic control was unsatisfactory in this patients population (HbA1c 7.5 ± 3.4% [58.7 ± 13.4 mmol/mol]). Conclusions The AWARE App proved to be a practical tool for cardiovascular risk stratification of T2DM patients in real-world clinical practice. Type 2 diabetes mellitus (dpeaa)DE-He213 Cardiovascular risk (dpeaa)DE-He213 Digital tools (dpeaa)DE-He213 Glucagon like peptide 1 receptor agonists (dpeaa)DE-He213 Sodium-glucose co-transporter-2 inhibitors (dpeaa)DE-He213 Manfrini, Roberto aut Mirani, Marco aut Bucciarelli, Loredana aut Zakaria, Ahmed S. aut Piccini, Sara aut Ghelardi, Renata aut Lunati, Maria Elena aut Rodovalho, Sylka aut Bifari, Francesco aut Fiorina, Paolo aut Folli, Franco aut Enthalten in Acta diabetologica Mailand : Springer, 1964 60(2023), 9 vom: 04. Juni, Seite 1257-1266 (DE-627)266886469 (DE-600)1468518-8 1432-5233 nnns volume:60 year:2023 number:9 day:04 month:06 pages:1257-1266 https://dx.doi.org/10.1007/s00592-023-02115-x kostenfrei Volltext GBV_USEFLAG_A SYSFLAG_A GBV_SPRINGER GBV_ILN_11 GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_32 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_69 GBV_ILN_70 GBV_ILN_73 GBV_ILN_74 GBV_ILN_90 GBV_ILN_95 GBV_ILN_100 GBV_ILN_101 GBV_ILN_105 GBV_ILN_110 GBV_ILN_120 GBV_ILN_138 GBV_ILN_150 GBV_ILN_151 GBV_ILN_152 GBV_ILN_161 GBV_ILN_170 GBV_ILN_171 GBV_ILN_187 GBV_ILN_213 GBV_ILN_224 GBV_ILN_230 GBV_ILN_250 GBV_ILN_267 GBV_ILN_281 GBV_ILN_285 GBV_ILN_293 GBV_ILN_370 GBV_ILN_602 GBV_ILN_636 GBV_ILN_702 GBV_ILN_711 GBV_ILN_2001 GBV_ILN_2003 GBV_ILN_2004 GBV_ILN_2005 GBV_ILN_2006 GBV_ILN_2007 GBV_ILN_2008 GBV_ILN_2009 GBV_ILN_2010 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2015 GBV_ILN_2020 GBV_ILN_2021 GBV_ILN_2025 GBV_ILN_2026 GBV_ILN_2027 GBV_ILN_2031 GBV_ILN_2034 GBV_ILN_2037 GBV_ILN_2038 GBV_ILN_2039 GBV_ILN_2044 GBV_ILN_2048 GBV_ILN_2049 GBV_ILN_2050 GBV_ILN_2055 GBV_ILN_2056 GBV_ILN_2057 GBV_ILN_2059 GBV_ILN_2061 GBV_ILN_2064 GBV_ILN_2065 GBV_ILN_2068 GBV_ILN_2088 GBV_ILN_2093 GBV_ILN_2106 GBV_ILN_2107 GBV_ILN_2110 GBV_ILN_2111 GBV_ILN_2112 GBV_ILN_2113 GBV_ILN_2118 GBV_ILN_2129 GBV_ILN_2143 GBV_ILN_2144 GBV_ILN_2147 GBV_ILN_2148 GBV_ILN_2152 GBV_ILN_2153 GBV_ILN_2188 GBV_ILN_2190 GBV_ILN_2232 GBV_ILN_2336 GBV_ILN_2446 GBV_ILN_2470 GBV_ILN_2472 GBV_ILN_2507 GBV_ILN_2522 GBV_ILN_2548 GBV_ILN_4035 GBV_ILN_4037 GBV_ILN_4046 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4242 GBV_ILN_4246 GBV_ILN_4249 GBV_ILN_4251 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4326 GBV_ILN_4328 GBV_ILN_4333 GBV_ILN_4334 GBV_ILN_4335 GBV_ILN_4336 GBV_ILN_4338 GBV_ILN_4393 GBV_ILN_4700 AR 60 2023 9 04 06 1257-1266 |
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10.1007/s00592-023-02115-x doi (DE-627)SPR052315479 (SPR)s00592-023-02115-x-e DE-627 ger DE-627 rakwb eng Berra, Cesare verfasserin (orcid)0000-0001-8431-8160 aut AWARE A novel web application to rapidly assess cardiovascular risk in type 2 diabetes mellitus 2023 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier © The Author(s) 2023 Aim To describe the development of the AWARE App, a novel web application for the rapid assessment of cardiovascular risk in Type 2 Diabetes Mellitus (T2DM) patients. We also tested the feasibility of using this App in clinical practice. Methods Based on 2019 European Society of Cardiology/European Association for the Study of Diabetes criteria for cardiovascular risk stratification in T2DM, the AWARE App classifies patients into very high ($ VH_{CVR} $), high ($ H_{CVR} $) and moderate ($ M_{CVR} $) cardiovascular risk categories. In this retrospective clinical study, we employed the App to assess the cardiovascular risk of T2DM patients, while also collecting data about current glycaemic control and pharmacological treatment. Results 2243 T2DM consecutive patients were evaluated. 72.2% of the patients were $ VH_{CVR} $, 8.9% were $ H_{CVR} $, 0.8% were $ M_{CVR} $ while 18.2% did not fit into any of the risk categories and were classified as “moderate-to-high” ($ MH_{CVR} $). Compared with the other groups, patients with $ VH_{CVD} $ were more frequently ≥ 65 years old (68.9%), with a longer disease duration (≥ 10 years [56.8%]), a history of cardiovascular disease (41.4%), organ damage (35.5%) and a higher numbers of cardiovascular risk factors. Patients with $ MH_{CVD} $ generally had disease duration < 10 years (96%), younger age (50–60 years [55%]), no history of cardiovascular disease, no organ damage, and 1–2 cardiovascular risk factors (89%). Novel drugs such as Glucagon Like Peptyde 1 Receptor Agonists or Sodium-Glucose Linked Transporter 2 inhibitors were prescribed only to 26.3% of the patients with $ VH_{CVR} $ and to 24.7% of those with $ H_{CVR} $. Glycaemic control was unsatisfactory in this patients population (HbA1c 7.5 ± 3.4% [58.7 ± 13.4 mmol/mol]). Conclusions The AWARE App proved to be a practical tool for cardiovascular risk stratification of T2DM patients in real-world clinical practice. Type 2 diabetes mellitus (dpeaa)DE-He213 Cardiovascular risk (dpeaa)DE-He213 Digital tools (dpeaa)DE-He213 Glucagon like peptide 1 receptor agonists (dpeaa)DE-He213 Sodium-glucose co-transporter-2 inhibitors (dpeaa)DE-He213 Manfrini, Roberto aut Mirani, Marco aut Bucciarelli, Loredana aut Zakaria, Ahmed S. aut Piccini, Sara aut Ghelardi, Renata aut Lunati, Maria Elena aut Rodovalho, Sylka aut Bifari, Francesco aut Fiorina, Paolo aut Folli, Franco aut Enthalten in Acta diabetologica Mailand : Springer, 1964 60(2023), 9 vom: 04. Juni, Seite 1257-1266 (DE-627)266886469 (DE-600)1468518-8 1432-5233 nnns volume:60 year:2023 number:9 day:04 month:06 pages:1257-1266 https://dx.doi.org/10.1007/s00592-023-02115-x kostenfrei Volltext GBV_USEFLAG_A SYSFLAG_A GBV_SPRINGER GBV_ILN_11 GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_32 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_69 GBV_ILN_70 GBV_ILN_73 GBV_ILN_74 GBV_ILN_90 GBV_ILN_95 GBV_ILN_100 GBV_ILN_101 GBV_ILN_105 GBV_ILN_110 GBV_ILN_120 GBV_ILN_138 GBV_ILN_150 GBV_ILN_151 GBV_ILN_152 GBV_ILN_161 GBV_ILN_170 GBV_ILN_171 GBV_ILN_187 GBV_ILN_213 GBV_ILN_224 GBV_ILN_230 GBV_ILN_250 GBV_ILN_267 GBV_ILN_281 GBV_ILN_285 GBV_ILN_293 GBV_ILN_370 GBV_ILN_602 GBV_ILN_636 GBV_ILN_702 GBV_ILN_711 GBV_ILN_2001 GBV_ILN_2003 GBV_ILN_2004 GBV_ILN_2005 GBV_ILN_2006 GBV_ILN_2007 GBV_ILN_2008 GBV_ILN_2009 GBV_ILN_2010 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2015 GBV_ILN_2020 GBV_ILN_2021 GBV_ILN_2025 GBV_ILN_2026 GBV_ILN_2027 GBV_ILN_2031 GBV_ILN_2034 GBV_ILN_2037 GBV_ILN_2038 GBV_ILN_2039 GBV_ILN_2044 GBV_ILN_2048 GBV_ILN_2049 GBV_ILN_2050 GBV_ILN_2055 GBV_ILN_2056 GBV_ILN_2057 GBV_ILN_2059 GBV_ILN_2061 GBV_ILN_2064 GBV_ILN_2065 GBV_ILN_2068 GBV_ILN_2088 GBV_ILN_2093 GBV_ILN_2106 GBV_ILN_2107 GBV_ILN_2110 GBV_ILN_2111 GBV_ILN_2112 GBV_ILN_2113 GBV_ILN_2118 GBV_ILN_2129 GBV_ILN_2143 GBV_ILN_2144 GBV_ILN_2147 GBV_ILN_2148 GBV_ILN_2152 GBV_ILN_2153 GBV_ILN_2188 GBV_ILN_2190 GBV_ILN_2232 GBV_ILN_2336 GBV_ILN_2446 GBV_ILN_2470 GBV_ILN_2472 GBV_ILN_2507 GBV_ILN_2522 GBV_ILN_2548 GBV_ILN_4035 GBV_ILN_4037 GBV_ILN_4046 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4242 GBV_ILN_4246 GBV_ILN_4249 GBV_ILN_4251 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4326 GBV_ILN_4328 GBV_ILN_4333 GBV_ILN_4334 GBV_ILN_4335 GBV_ILN_4336 GBV_ILN_4338 GBV_ILN_4393 GBV_ILN_4700 AR 60 2023 9 04 06 1257-1266 |
| allfieldsGer |
10.1007/s00592-023-02115-x doi (DE-627)SPR052315479 (SPR)s00592-023-02115-x-e DE-627 ger DE-627 rakwb eng Berra, Cesare verfasserin (orcid)0000-0001-8431-8160 aut AWARE A novel web application to rapidly assess cardiovascular risk in type 2 diabetes mellitus 2023 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier © The Author(s) 2023 Aim To describe the development of the AWARE App, a novel web application for the rapid assessment of cardiovascular risk in Type 2 Diabetes Mellitus (T2DM) patients. We also tested the feasibility of using this App in clinical practice. Methods Based on 2019 European Society of Cardiology/European Association for the Study of Diabetes criteria for cardiovascular risk stratification in T2DM, the AWARE App classifies patients into very high ($ VH_{CVR} $), high ($ H_{CVR} $) and moderate ($ M_{CVR} $) cardiovascular risk categories. In this retrospective clinical study, we employed the App to assess the cardiovascular risk of T2DM patients, while also collecting data about current glycaemic control and pharmacological treatment. Results 2243 T2DM consecutive patients were evaluated. 72.2% of the patients were $ VH_{CVR} $, 8.9% were $ H_{CVR} $, 0.8% were $ M_{CVR} $ while 18.2% did not fit into any of the risk categories and were classified as “moderate-to-high” ($ MH_{CVR} $). Compared with the other groups, patients with $ VH_{CVD} $ were more frequently ≥ 65 years old (68.9%), with a longer disease duration (≥ 10 years [56.8%]), a history of cardiovascular disease (41.4%), organ damage (35.5%) and a higher numbers of cardiovascular risk factors. Patients with $ MH_{CVD} $ generally had disease duration < 10 years (96%), younger age (50–60 years [55%]), no history of cardiovascular disease, no organ damage, and 1–2 cardiovascular risk factors (89%). Novel drugs such as Glucagon Like Peptyde 1 Receptor Agonists or Sodium-Glucose Linked Transporter 2 inhibitors were prescribed only to 26.3% of the patients with $ VH_{CVR} $ and to 24.7% of those with $ H_{CVR} $. Glycaemic control was unsatisfactory in this patients population (HbA1c 7.5 ± 3.4% [58.7 ± 13.4 mmol/mol]). Conclusions The AWARE App proved to be a practical tool for cardiovascular risk stratification of T2DM patients in real-world clinical practice. Type 2 diabetes mellitus (dpeaa)DE-He213 Cardiovascular risk (dpeaa)DE-He213 Digital tools (dpeaa)DE-He213 Glucagon like peptide 1 receptor agonists (dpeaa)DE-He213 Sodium-glucose co-transporter-2 inhibitors (dpeaa)DE-He213 Manfrini, Roberto aut Mirani, Marco aut Bucciarelli, Loredana aut Zakaria, Ahmed S. aut Piccini, Sara aut Ghelardi, Renata aut Lunati, Maria Elena aut Rodovalho, Sylka aut Bifari, Francesco aut Fiorina, Paolo aut Folli, Franco aut Enthalten in Acta diabetologica Mailand : Springer, 1964 60(2023), 9 vom: 04. Juni, Seite 1257-1266 (DE-627)266886469 (DE-600)1468518-8 1432-5233 nnns volume:60 year:2023 number:9 day:04 month:06 pages:1257-1266 https://dx.doi.org/10.1007/s00592-023-02115-x kostenfrei Volltext GBV_USEFLAG_A SYSFLAG_A GBV_SPRINGER GBV_ILN_11 GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_32 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_69 GBV_ILN_70 GBV_ILN_73 GBV_ILN_74 GBV_ILN_90 GBV_ILN_95 GBV_ILN_100 GBV_ILN_101 GBV_ILN_105 GBV_ILN_110 GBV_ILN_120 GBV_ILN_138 GBV_ILN_150 GBV_ILN_151 GBV_ILN_152 GBV_ILN_161 GBV_ILN_170 GBV_ILN_171 GBV_ILN_187 GBV_ILN_213 GBV_ILN_224 GBV_ILN_230 GBV_ILN_250 GBV_ILN_267 GBV_ILN_281 GBV_ILN_285 GBV_ILN_293 GBV_ILN_370 GBV_ILN_602 GBV_ILN_636 GBV_ILN_702 GBV_ILN_711 GBV_ILN_2001 GBV_ILN_2003 GBV_ILN_2004 GBV_ILN_2005 GBV_ILN_2006 GBV_ILN_2007 GBV_ILN_2008 GBV_ILN_2009 GBV_ILN_2010 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2015 GBV_ILN_2020 GBV_ILN_2021 GBV_ILN_2025 GBV_ILN_2026 GBV_ILN_2027 GBV_ILN_2031 GBV_ILN_2034 GBV_ILN_2037 GBV_ILN_2038 GBV_ILN_2039 GBV_ILN_2044 GBV_ILN_2048 GBV_ILN_2049 GBV_ILN_2050 GBV_ILN_2055 GBV_ILN_2056 GBV_ILN_2057 GBV_ILN_2059 GBV_ILN_2061 GBV_ILN_2064 GBV_ILN_2065 GBV_ILN_2068 GBV_ILN_2088 GBV_ILN_2093 GBV_ILN_2106 GBV_ILN_2107 GBV_ILN_2110 GBV_ILN_2111 GBV_ILN_2112 GBV_ILN_2113 GBV_ILN_2118 GBV_ILN_2129 GBV_ILN_2143 GBV_ILN_2144 GBV_ILN_2147 GBV_ILN_2148 GBV_ILN_2152 GBV_ILN_2153 GBV_ILN_2188 GBV_ILN_2190 GBV_ILN_2232 GBV_ILN_2336 GBV_ILN_2446 GBV_ILN_2470 GBV_ILN_2472 GBV_ILN_2507 GBV_ILN_2522 GBV_ILN_2548 GBV_ILN_4035 GBV_ILN_4037 GBV_ILN_4046 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4242 GBV_ILN_4246 GBV_ILN_4249 GBV_ILN_4251 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4326 GBV_ILN_4328 GBV_ILN_4333 GBV_ILN_4334 GBV_ILN_4335 GBV_ILN_4336 GBV_ILN_4338 GBV_ILN_4393 GBV_ILN_4700 AR 60 2023 9 04 06 1257-1266 |
| allfieldsSound |
10.1007/s00592-023-02115-x doi (DE-627)SPR052315479 (SPR)s00592-023-02115-x-e DE-627 ger DE-627 rakwb eng Berra, Cesare verfasserin (orcid)0000-0001-8431-8160 aut AWARE A novel web application to rapidly assess cardiovascular risk in type 2 diabetes mellitus 2023 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier © The Author(s) 2023 Aim To describe the development of the AWARE App, a novel web application for the rapid assessment of cardiovascular risk in Type 2 Diabetes Mellitus (T2DM) patients. We also tested the feasibility of using this App in clinical practice. Methods Based on 2019 European Society of Cardiology/European Association for the Study of Diabetes criteria for cardiovascular risk stratification in T2DM, the AWARE App classifies patients into very high ($ VH_{CVR} $), high ($ H_{CVR} $) and moderate ($ M_{CVR} $) cardiovascular risk categories. In this retrospective clinical study, we employed the App to assess the cardiovascular risk of T2DM patients, while also collecting data about current glycaemic control and pharmacological treatment. Results 2243 T2DM consecutive patients were evaluated. 72.2% of the patients were $ VH_{CVR} $, 8.9% were $ H_{CVR} $, 0.8% were $ M_{CVR} $ while 18.2% did not fit into any of the risk categories and were classified as “moderate-to-high” ($ MH_{CVR} $). Compared with the other groups, patients with $ VH_{CVD} $ were more frequently ≥ 65 years old (68.9%), with a longer disease duration (≥ 10 years [56.8%]), a history of cardiovascular disease (41.4%), organ damage (35.5%) and a higher numbers of cardiovascular risk factors. Patients with $ MH_{CVD} $ generally had disease duration < 10 years (96%), younger age (50–60 years [55%]), no history of cardiovascular disease, no organ damage, and 1–2 cardiovascular risk factors (89%). Novel drugs such as Glucagon Like Peptyde 1 Receptor Agonists or Sodium-Glucose Linked Transporter 2 inhibitors were prescribed only to 26.3% of the patients with $ VH_{CVR} $ and to 24.7% of those with $ H_{CVR} $. Glycaemic control was unsatisfactory in this patients population (HbA1c 7.5 ± 3.4% [58.7 ± 13.4 mmol/mol]). Conclusions The AWARE App proved to be a practical tool for cardiovascular risk stratification of T2DM patients in real-world clinical practice. Type 2 diabetes mellitus (dpeaa)DE-He213 Cardiovascular risk (dpeaa)DE-He213 Digital tools (dpeaa)DE-He213 Glucagon like peptide 1 receptor agonists (dpeaa)DE-He213 Sodium-glucose co-transporter-2 inhibitors (dpeaa)DE-He213 Manfrini, Roberto aut Mirani, Marco aut Bucciarelli, Loredana aut Zakaria, Ahmed S. aut Piccini, Sara aut Ghelardi, Renata aut Lunati, Maria Elena aut Rodovalho, Sylka aut Bifari, Francesco aut Fiorina, Paolo aut Folli, Franco aut Enthalten in Acta diabetologica Mailand : Springer, 1964 60(2023), 9 vom: 04. Juni, Seite 1257-1266 (DE-627)266886469 (DE-600)1468518-8 1432-5233 nnns volume:60 year:2023 number:9 day:04 month:06 pages:1257-1266 https://dx.doi.org/10.1007/s00592-023-02115-x kostenfrei Volltext GBV_USEFLAG_A SYSFLAG_A GBV_SPRINGER GBV_ILN_11 GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_32 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_69 GBV_ILN_70 GBV_ILN_73 GBV_ILN_74 GBV_ILN_90 GBV_ILN_95 GBV_ILN_100 GBV_ILN_101 GBV_ILN_105 GBV_ILN_110 GBV_ILN_120 GBV_ILN_138 GBV_ILN_150 GBV_ILN_151 GBV_ILN_152 GBV_ILN_161 GBV_ILN_170 GBV_ILN_171 GBV_ILN_187 GBV_ILN_213 GBV_ILN_224 GBV_ILN_230 GBV_ILN_250 GBV_ILN_267 GBV_ILN_281 GBV_ILN_285 GBV_ILN_293 GBV_ILN_370 GBV_ILN_602 GBV_ILN_636 GBV_ILN_702 GBV_ILN_711 GBV_ILN_2001 GBV_ILN_2003 GBV_ILN_2004 GBV_ILN_2005 GBV_ILN_2006 GBV_ILN_2007 GBV_ILN_2008 GBV_ILN_2009 GBV_ILN_2010 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2015 GBV_ILN_2020 GBV_ILN_2021 GBV_ILN_2025 GBV_ILN_2026 GBV_ILN_2027 GBV_ILN_2031 GBV_ILN_2034 GBV_ILN_2037 GBV_ILN_2038 GBV_ILN_2039 GBV_ILN_2044 GBV_ILN_2048 GBV_ILN_2049 GBV_ILN_2050 GBV_ILN_2055 GBV_ILN_2056 GBV_ILN_2057 GBV_ILN_2059 GBV_ILN_2061 GBV_ILN_2064 GBV_ILN_2065 GBV_ILN_2068 GBV_ILN_2088 GBV_ILN_2093 GBV_ILN_2106 GBV_ILN_2107 GBV_ILN_2110 GBV_ILN_2111 GBV_ILN_2112 GBV_ILN_2113 GBV_ILN_2118 GBV_ILN_2129 GBV_ILN_2143 GBV_ILN_2144 GBV_ILN_2147 GBV_ILN_2148 GBV_ILN_2152 GBV_ILN_2153 GBV_ILN_2188 GBV_ILN_2190 GBV_ILN_2232 GBV_ILN_2336 GBV_ILN_2446 GBV_ILN_2470 GBV_ILN_2472 GBV_ILN_2507 GBV_ILN_2522 GBV_ILN_2548 GBV_ILN_4035 GBV_ILN_4037 GBV_ILN_4046 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4242 GBV_ILN_4246 GBV_ILN_4249 GBV_ILN_4251 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4326 GBV_ILN_4328 GBV_ILN_4333 GBV_ILN_4334 GBV_ILN_4335 GBV_ILN_4336 GBV_ILN_4338 GBV_ILN_4393 GBV_ILN_4700 AR 60 2023 9 04 06 1257-1266 |
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Enthalten in Acta diabetologica 60(2023), 9 vom: 04. Juni, Seite 1257-1266 volume:60 year:2023 number:9 day:04 month:06 pages:1257-1266 |
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Type 2 diabetes mellitus Cardiovascular risk Digital tools Glucagon like peptide 1 receptor agonists Sodium-glucose co-transporter-2 inhibitors |
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Berra, Cesare @@aut@@ Manfrini, Roberto @@aut@@ Mirani, Marco @@aut@@ Bucciarelli, Loredana @@aut@@ Zakaria, Ahmed S. @@aut@@ Piccini, Sara @@aut@@ Ghelardi, Renata @@aut@@ Lunati, Maria Elena @@aut@@ Rodovalho, Sylka @@aut@@ Bifari, Francesco @@aut@@ Fiorina, Paolo @@aut@@ Folli, Franco @@aut@@ |
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<?xml version="1.0" encoding="UTF-8"?><collection xmlns="http://www.loc.gov/MARC21/slim"><record><leader>01000naa a22002652 4500</leader><controlfield tag="001">SPR052315479</controlfield><controlfield tag="003">DE-627</controlfield><controlfield tag="005">20230721064717.0</controlfield><controlfield tag="007">cr uuu---uuuuu</controlfield><controlfield tag="008">230721s2023 xx |||||o 00| ||eng c</controlfield><datafield tag="024" ind1="7" ind2=" "><subfield code="a">10.1007/s00592-023-02115-x</subfield><subfield code="2">doi</subfield></datafield><datafield tag="035" ind1=" " ind2=" "><subfield code="a">(DE-627)SPR052315479</subfield></datafield><datafield tag="035" ind1=" " ind2=" "><subfield code="a">(SPR)s00592-023-02115-x-e</subfield></datafield><datafield tag="040" ind1=" " ind2=" "><subfield code="a">DE-627</subfield><subfield code="b">ger</subfield><subfield code="c">DE-627</subfield><subfield code="e">rakwb</subfield></datafield><datafield tag="041" ind1=" " ind2=" "><subfield code="a">eng</subfield></datafield><datafield tag="100" ind1="1" ind2=" "><subfield code="a">Berra, Cesare</subfield><subfield code="e">verfasserin</subfield><subfield code="0">(orcid)0000-0001-8431-8160</subfield><subfield code="4">aut</subfield></datafield><datafield tag="245" ind1="1" ind2="0"><subfield code="a">AWARE A novel web application to rapidly assess cardiovascular risk in type 2 diabetes mellitus</subfield></datafield><datafield tag="264" ind1=" " ind2="1"><subfield code="c">2023</subfield></datafield><datafield tag="336" ind1=" " ind2=" "><subfield code="a">Text</subfield><subfield code="b">txt</subfield><subfield code="2">rdacontent</subfield></datafield><datafield tag="337" ind1=" " ind2=" "><subfield code="a">Computermedien</subfield><subfield code="b">c</subfield><subfield code="2">rdamedia</subfield></datafield><datafield tag="338" ind1=" " ind2=" "><subfield code="a">Online-Ressource</subfield><subfield code="b">cr</subfield><subfield code="2">rdacarrier</subfield></datafield><datafield tag="500" ind1=" " ind2=" "><subfield code="a">© The Author(s) 2023</subfield></datafield><datafield tag="520" ind1=" " ind2=" "><subfield code="a">Aim To describe the development of the AWARE App, a novel web application for the rapid assessment of cardiovascular risk in Type 2 Diabetes Mellitus (T2DM) patients. We also tested the feasibility of using this App in clinical practice. Methods Based on 2019 European Society of Cardiology/European Association for the Study of Diabetes criteria for cardiovascular risk stratification in T2DM, the AWARE App classifies patients into very high ($ VH_{CVR} $), high ($ H_{CVR} $) and moderate ($ M_{CVR} $) cardiovascular risk categories. In this retrospective clinical study, we employed the App to assess the cardiovascular risk of T2DM patients, while also collecting data about current glycaemic control and pharmacological treatment. Results 2243 T2DM consecutive patients were evaluated. 72.2% of the patients were $ VH_{CVR} $, 8.9% were $ H_{CVR} $, 0.8% were $ M_{CVR} $ while 18.2% did not fit into any of the risk categories and were classified as “moderate-to-high” ($ MH_{CVR} $). Compared with the other groups, patients with $ VH_{CVD} $ were more frequently ≥ 65 years old (68.9%), with a longer disease duration (≥ 10 years [56.8%]), a history of cardiovascular disease (41.4%), organ damage (35.5%) and a higher numbers of cardiovascular risk factors. Patients with $ MH_{CVD} $ generally had disease duration < 10 years (96%), younger age (50–60 years [55%]), no history of cardiovascular disease, no organ damage, and 1–2 cardiovascular risk factors (89%). Novel drugs such as Glucagon Like Peptyde 1 Receptor Agonists or Sodium-Glucose Linked Transporter 2 inhibitors were prescribed only to 26.3% of the patients with $ VH_{CVR} $ and to 24.7% of those with $ H_{CVR} $. Glycaemic control was unsatisfactory in this patients population (HbA1c 7.5 ± 3.4% [58.7 ± 13.4 mmol/mol]). 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Berra, Cesare |
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AWARE A novel web application to rapidly assess cardiovascular risk in type 2 diabetes mellitus Type 2 diabetes mellitus (dpeaa)DE-He213 Cardiovascular risk (dpeaa)DE-He213 Digital tools (dpeaa)DE-He213 Glucagon like peptide 1 receptor agonists (dpeaa)DE-He213 Sodium-glucose co-transporter-2 inhibitors (dpeaa)DE-He213 |
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Berra, Cesare Manfrini, Roberto Mirani, Marco Bucciarelli, Loredana Zakaria, Ahmed S. Piccini, Sara Ghelardi, Renata Lunati, Maria Elena Rodovalho, Sylka Bifari, Francesco Fiorina, Paolo Folli, Franco |
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Elektronische Aufsätze |
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Berra, Cesare |
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10.1007/s00592-023-02115-x |
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aware a novel web application to rapidly assess cardiovascular risk in type 2 diabetes mellitus |
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AWARE A novel web application to rapidly assess cardiovascular risk in type 2 diabetes mellitus |
| abstract |
Aim To describe the development of the AWARE App, a novel web application for the rapid assessment of cardiovascular risk in Type 2 Diabetes Mellitus (T2DM) patients. We also tested the feasibility of using this App in clinical practice. Methods Based on 2019 European Society of Cardiology/European Association for the Study of Diabetes criteria for cardiovascular risk stratification in T2DM, the AWARE App classifies patients into very high ($ VH_{CVR} $), high ($ H_{CVR} $) and moderate ($ M_{CVR} $) cardiovascular risk categories. In this retrospective clinical study, we employed the App to assess the cardiovascular risk of T2DM patients, while also collecting data about current glycaemic control and pharmacological treatment. Results 2243 T2DM consecutive patients were evaluated. 72.2% of the patients were $ VH_{CVR} $, 8.9% were $ H_{CVR} $, 0.8% were $ M_{CVR} $ while 18.2% did not fit into any of the risk categories and were classified as “moderate-to-high” ($ MH_{CVR} $). Compared with the other groups, patients with $ VH_{CVD} $ were more frequently ≥ 65 years old (68.9%), with a longer disease duration (≥ 10 years [56.8%]), a history of cardiovascular disease (41.4%), organ damage (35.5%) and a higher numbers of cardiovascular risk factors. Patients with $ MH_{CVD} $ generally had disease duration < 10 years (96%), younger age (50–60 years [55%]), no history of cardiovascular disease, no organ damage, and 1–2 cardiovascular risk factors (89%). Novel drugs such as Glucagon Like Peptyde 1 Receptor Agonists or Sodium-Glucose Linked Transporter 2 inhibitors were prescribed only to 26.3% of the patients with $ VH_{CVR} $ and to 24.7% of those with $ H_{CVR} $. Glycaemic control was unsatisfactory in this patients population (HbA1c 7.5 ± 3.4% [58.7 ± 13.4 mmol/mol]). Conclusions The AWARE App proved to be a practical tool for cardiovascular risk stratification of T2DM patients in real-world clinical practice. © The Author(s) 2023 |
| abstractGer |
Aim To describe the development of the AWARE App, a novel web application for the rapid assessment of cardiovascular risk in Type 2 Diabetes Mellitus (T2DM) patients. We also tested the feasibility of using this App in clinical practice. Methods Based on 2019 European Society of Cardiology/European Association for the Study of Diabetes criteria for cardiovascular risk stratification in T2DM, the AWARE App classifies patients into very high ($ VH_{CVR} $), high ($ H_{CVR} $) and moderate ($ M_{CVR} $) cardiovascular risk categories. In this retrospective clinical study, we employed the App to assess the cardiovascular risk of T2DM patients, while also collecting data about current glycaemic control and pharmacological treatment. Results 2243 T2DM consecutive patients were evaluated. 72.2% of the patients were $ VH_{CVR} $, 8.9% were $ H_{CVR} $, 0.8% were $ M_{CVR} $ while 18.2% did not fit into any of the risk categories and were classified as “moderate-to-high” ($ MH_{CVR} $). Compared with the other groups, patients with $ VH_{CVD} $ were more frequently ≥ 65 years old (68.9%), with a longer disease duration (≥ 10 years [56.8%]), a history of cardiovascular disease (41.4%), organ damage (35.5%) and a higher numbers of cardiovascular risk factors. Patients with $ MH_{CVD} $ generally had disease duration < 10 years (96%), younger age (50–60 years [55%]), no history of cardiovascular disease, no organ damage, and 1–2 cardiovascular risk factors (89%). Novel drugs such as Glucagon Like Peptyde 1 Receptor Agonists or Sodium-Glucose Linked Transporter 2 inhibitors were prescribed only to 26.3% of the patients with $ VH_{CVR} $ and to 24.7% of those with $ H_{CVR} $. Glycaemic control was unsatisfactory in this patients population (HbA1c 7.5 ± 3.4% [58.7 ± 13.4 mmol/mol]). Conclusions The AWARE App proved to be a practical tool for cardiovascular risk stratification of T2DM patients in real-world clinical practice. © The Author(s) 2023 |
| abstract_unstemmed |
Aim To describe the development of the AWARE App, a novel web application for the rapid assessment of cardiovascular risk in Type 2 Diabetes Mellitus (T2DM) patients. We also tested the feasibility of using this App in clinical practice. Methods Based on 2019 European Society of Cardiology/European Association for the Study of Diabetes criteria for cardiovascular risk stratification in T2DM, the AWARE App classifies patients into very high ($ VH_{CVR} $), high ($ H_{CVR} $) and moderate ($ M_{CVR} $) cardiovascular risk categories. In this retrospective clinical study, we employed the App to assess the cardiovascular risk of T2DM patients, while also collecting data about current glycaemic control and pharmacological treatment. Results 2243 T2DM consecutive patients were evaluated. 72.2% of the patients were $ VH_{CVR} $, 8.9% were $ H_{CVR} $, 0.8% were $ M_{CVR} $ while 18.2% did not fit into any of the risk categories and were classified as “moderate-to-high” ($ MH_{CVR} $). Compared with the other groups, patients with $ VH_{CVD} $ were more frequently ≥ 65 years old (68.9%), with a longer disease duration (≥ 10 years [56.8%]), a history of cardiovascular disease (41.4%), organ damage (35.5%) and a higher numbers of cardiovascular risk factors. Patients with $ MH_{CVD} $ generally had disease duration < 10 years (96%), younger age (50–60 years [55%]), no history of cardiovascular disease, no organ damage, and 1–2 cardiovascular risk factors (89%). Novel drugs such as Glucagon Like Peptyde 1 Receptor Agonists or Sodium-Glucose Linked Transporter 2 inhibitors were prescribed only to 26.3% of the patients with $ VH_{CVR} $ and to 24.7% of those with $ H_{CVR} $. Glycaemic control was unsatisfactory in this patients population (HbA1c 7.5 ± 3.4% [58.7 ± 13.4 mmol/mol]). Conclusions The AWARE App proved to be a practical tool for cardiovascular risk stratification of T2DM patients in real-world clinical practice. © The Author(s) 2023 |
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AWARE A novel web application to rapidly assess cardiovascular risk in type 2 diabetes mellitus |
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Manfrini, Roberto Mirani, Marco Bucciarelli, Loredana Zakaria, Ahmed S. Piccini, Sara Ghelardi, Renata Lunati, Maria Elena Rodovalho, Sylka Bifari, Francesco Fiorina, Paolo Folli, Franco |
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Manfrini, Roberto Mirani, Marco Bucciarelli, Loredana Zakaria, Ahmed S. Piccini, Sara Ghelardi, Renata Lunati, Maria Elena Rodovalho, Sylka Bifari, Francesco Fiorina, Paolo Folli, Franco |
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| score |
7.3979836 |