Hyperactivity in patients with narcolepsy and idiopathic hypersomnia: an exploratory study

Introduction Patients with either Idiopathic Hypersomnia or Narcolepsy demonstrate excessive daytime somnolence (EDS) with resultant inattention mimicking Attention Deficit Hyperactivity Disorder (ADHD). Patients with ADHD also often express sleep problems including EDS. Thus, patients with ADHD and patients with idiopathic hypersomnia or narcolepsy may share inattention and daytime drowsiness as common features. However, it is not known whether EDS patients with idiopathic hypersomnia or narcolepsy also have increased movement (hyperactivity) like ADHD patients, the determination of which is the purpose of this study. Methods We studied 12 patients (7 Narcolepsy type 2 and 5 Idiopathic Hypersomnia) with EDS as shown by Multiple Sleep Latency Test which served as the gold standard for entry into the study. Twelve subjects without symptoms of EDS served as the control group. None of the participants had a previous history of ADHD. Each participant underwent a one-hour session laying at 45 degrees with surveys about the need to move and actigraphy as an objective measure of movement. Results Sleep-disordered patients with EDS reported more symptoms of inattention and hyperactivity on the ADHD Self-Report Scale. At each of the time points patients with EDS had a clear trend to express the need to move more than controls on the Suggested Immobilization Test (SIT). For the total 60 min, a large effect size for the need to move during the SIT test was found between patients and controls (Cohen’s d = 0.61, p = 0.01). Patients with EDS did not express a need to move more to combat drowsiness than controls, nor did actigraphy show any difference in objective movement between patients and controls during the SIT. Conclusion Patients with EDS express inattention and a need to move more than controls. However, hyperactivity was not verified by objective measurement, nor did the EDS patients express a need to move to combat drowsiness more than controls. Thus, a hypothesis to be further tested, is whether narcolepsy and idiopathic hypersomnia may be more a model of the inattentive form of ADHD rather than the combined or inattentive/hyperactive form of ADHD. Further studies are needed to explore the relationship between EDS and hyperactivity. Ausführliche Beschreibung

Gespeichert in:

Autor*in:	Dodson, Caroline [verfasserIn] Spruyt, Karen Considine, Ciaran Thompson, Emily Ipsiroglu, Osman S. Bagai, Kanika Silvestri, Rosalia Couvadelli, Barbara Walters, Arthur S.

Format:	E-Artikel
Sprache:	Englisch

Erschienen:	2023

Schlagwörter:	Narcolepsy Idiopathic hypersomnia Attention-Deficit Hyperactivity Disorder (ADHD) Inattention Hyperactivity Hypoarousal Sleepiness Drowsiness Somnolence Suggested Immobilization Test (SIT)

Anmerkung:	© The Author(s) 2023

Übergeordnetes Werk:	Enthalten in: Sleep science and practice - [London] : BioMed Central, 2017, 7(2023), 1 vom: 21. Juli
Übergeordnetes Werk:	volume:7 ; year:2023 ; number:1 ; day:21 ; month:07

Links:	Volltext

DOI / URN:	10.1186/s41606-023-00088-y

Katalog-ID:	SPR052341178

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520			\|a Introduction Patients with either Idiopathic Hypersomnia or Narcolepsy demonstrate excessive daytime somnolence (EDS) with resultant inattention mimicking Attention Deficit Hyperactivity Disorder (ADHD). Patients with ADHD also often express sleep problems including EDS. Thus, patients with ADHD and patients with idiopathic hypersomnia or narcolepsy may share inattention and daytime drowsiness as common features. However, it is not known whether EDS patients with idiopathic hypersomnia or narcolepsy also have increased movement (hyperactivity) like ADHD patients, the determination of which is the purpose of this study. Methods We studied 12 patients (7 Narcolepsy type 2 and 5 Idiopathic Hypersomnia) with EDS as shown by Multiple Sleep Latency Test which served as the gold standard for entry into the study. Twelve subjects without symptoms of EDS served as the control group. None of the participants had a previous history of ADHD. Each participant underwent a one-hour session laying at 45 degrees with surveys about the need to move and actigraphy as an objective measure of movement. Results Sleep-disordered patients with EDS reported more symptoms of inattention and hyperactivity on the ADHD Self-Report Scale. At each of the time points patients with EDS had a clear trend to express the need to move more than controls on the Suggested Immobilization Test (SIT). For the total 60 min, a large effect size for the need to move during the SIT test was found between patients and controls (Cohen’s d = 0.61, p = 0.01). Patients with EDS did not express a need to move more to combat drowsiness than controls, nor did actigraphy show any difference in objective movement between patients and controls during the SIT. Conclusion Patients with EDS express inattention and a need to move more than controls. However, hyperactivity was not verified by objective measurement, nor did the EDS patients express a need to move to combat drowsiness more than controls. Thus, a hypothesis to be further tested, is whether narcolepsy and idiopathic hypersomnia may be more a model of the inattentive form of ADHD rather than the combined or inattentive/hyperactive form of ADHD. Further studies are needed to explore the relationship between EDS and hyperactivity.
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allfields	10.1186/s41606-023-00088-y doi (DE-627)SPR052341178 (SPR)s41606-023-00088-y-e DE-627 ger DE-627 rakwb eng Dodson, Caroline verfasserin aut Hyperactivity in patients with narcolepsy and idiopathic hypersomnia: an exploratory study 2023 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier © The Author(s) 2023 Introduction Patients with either Idiopathic Hypersomnia or Narcolepsy demonstrate excessive daytime somnolence (EDS) with resultant inattention mimicking Attention Deficit Hyperactivity Disorder (ADHD). Patients with ADHD also often express sleep problems including EDS. Thus, patients with ADHD and patients with idiopathic hypersomnia or narcolepsy may share inattention and daytime drowsiness as common features. However, it is not known whether EDS patients with idiopathic hypersomnia or narcolepsy also have increased movement (hyperactivity) like ADHD patients, the determination of which is the purpose of this study. Methods We studied 12 patients (7 Narcolepsy type 2 and 5 Idiopathic Hypersomnia) with EDS as shown by Multiple Sleep Latency Test which served as the gold standard for entry into the study. Twelve subjects without symptoms of EDS served as the control group. None of the participants had a previous history of ADHD. Each participant underwent a one-hour session laying at 45 degrees with surveys about the need to move and actigraphy as an objective measure of movement. Results Sleep-disordered patients with EDS reported more symptoms of inattention and hyperactivity on the ADHD Self-Report Scale. At each of the time points patients with EDS had a clear trend to express the need to move more than controls on the Suggested Immobilization Test (SIT). For the total 60 min, a large effect size for the need to move during the SIT test was found between patients and controls (Cohen’s d = 0.61, p = 0.01). Patients with EDS did not express a need to move more to combat drowsiness than controls, nor did actigraphy show any difference in objective movement between patients and controls during the SIT. Conclusion Patients with EDS express inattention and a need to move more than controls. However, hyperactivity was not verified by objective measurement, nor did the EDS patients express a need to move to combat drowsiness more than controls. Thus, a hypothesis to be further tested, is whether narcolepsy and idiopathic hypersomnia may be more a model of the inattentive form of ADHD rather than the combined or inattentive/hyperactive form of ADHD. Further studies are needed to explore the relationship between EDS and hyperactivity. Narcolepsy (dpeaa)DE-He213 Idiopathic hypersomnia (dpeaa)DE-He213 Attention-Deficit Hyperactivity Disorder (ADHD) (dpeaa)DE-He213 Inattention (dpeaa)DE-He213 Hyperactivity (dpeaa)DE-He213 Hypoarousal (dpeaa)DE-He213 Sleepiness (dpeaa)DE-He213 Drowsiness (dpeaa)DE-He213 Somnolence (dpeaa)DE-He213 Suggested Immobilization Test (SIT) (dpeaa)DE-He213 Spruyt, Karen aut Considine, Ciaran aut Thompson, Emily aut Ipsiroglu, Osman S. aut Bagai, Kanika aut Silvestri, Rosalia aut Couvadelli, Barbara aut Walters, Arthur S. aut Enthalten in Sleep science and practice [London] : BioMed Central, 2017 7(2023), 1 vom: 21. Juli (DE-627)880932333 (DE-600)2885817-7 2398-2683 nnns volume:7 year:2023 number:1 day:21 month:07 https://dx.doi.org/10.1186/s41606-023-00088-y kostenfrei Volltext GBV_USEFLAG_A SYSFLAG_A GBV_SPRINGER GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_2014 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 7 2023 1 21 07
spelling	10.1186/s41606-023-00088-y doi (DE-627)SPR052341178 (SPR)s41606-023-00088-y-e DE-627 ger DE-627 rakwb eng Dodson, Caroline verfasserin aut Hyperactivity in patients with narcolepsy and idiopathic hypersomnia: an exploratory study 2023 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier © The Author(s) 2023 Introduction Patients with either Idiopathic Hypersomnia or Narcolepsy demonstrate excessive daytime somnolence (EDS) with resultant inattention mimicking Attention Deficit Hyperactivity Disorder (ADHD). Patients with ADHD also often express sleep problems including EDS. Thus, patients with ADHD and patients with idiopathic hypersomnia or narcolepsy may share inattention and daytime drowsiness as common features. However, it is not known whether EDS patients with idiopathic hypersomnia or narcolepsy also have increased movement (hyperactivity) like ADHD patients, the determination of which is the purpose of this study. Methods We studied 12 patients (7 Narcolepsy type 2 and 5 Idiopathic Hypersomnia) with EDS as shown by Multiple Sleep Latency Test which served as the gold standard for entry into the study. Twelve subjects without symptoms of EDS served as the control group. None of the participants had a previous history of ADHD. Each participant underwent a one-hour session laying at 45 degrees with surveys about the need to move and actigraphy as an objective measure of movement. Results Sleep-disordered patients with EDS reported more symptoms of inattention and hyperactivity on the ADHD Self-Report Scale. At each of the time points patients with EDS had a clear trend to express the need to move more than controls on the Suggested Immobilization Test (SIT). For the total 60 min, a large effect size for the need to move during the SIT test was found between patients and controls (Cohen’s d = 0.61, p = 0.01). Patients with EDS did not express a need to move more to combat drowsiness than controls, nor did actigraphy show any difference in objective movement between patients and controls during the SIT. Conclusion Patients with EDS express inattention and a need to move more than controls. However, hyperactivity was not verified by objective measurement, nor did the EDS patients express a need to move to combat drowsiness more than controls. Thus, a hypothesis to be further tested, is whether narcolepsy and idiopathic hypersomnia may be more a model of the inattentive form of ADHD rather than the combined or inattentive/hyperactive form of ADHD. Further studies are needed to explore the relationship between EDS and hyperactivity. Narcolepsy (dpeaa)DE-He213 Idiopathic hypersomnia (dpeaa)DE-He213 Attention-Deficit Hyperactivity Disorder (ADHD) (dpeaa)DE-He213 Inattention (dpeaa)DE-He213 Hyperactivity (dpeaa)DE-He213 Hypoarousal (dpeaa)DE-He213 Sleepiness (dpeaa)DE-He213 Drowsiness (dpeaa)DE-He213 Somnolence (dpeaa)DE-He213 Suggested Immobilization Test (SIT) (dpeaa)DE-He213 Spruyt, Karen aut Considine, Ciaran aut Thompson, Emily aut Ipsiroglu, Osman S. aut Bagai, Kanika aut Silvestri, Rosalia aut Couvadelli, Barbara aut Walters, Arthur S. aut Enthalten in Sleep science and practice [London] : BioMed Central, 2017 7(2023), 1 vom: 21. Juli (DE-627)880932333 (DE-600)2885817-7 2398-2683 nnns volume:7 year:2023 number:1 day:21 month:07 https://dx.doi.org/10.1186/s41606-023-00088-y kostenfrei Volltext GBV_USEFLAG_A SYSFLAG_A GBV_SPRINGER GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_2014 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 7 2023 1 21 07
allfields_unstemmed	10.1186/s41606-023-00088-y doi (DE-627)SPR052341178 (SPR)s41606-023-00088-y-e DE-627 ger DE-627 rakwb eng Dodson, Caroline verfasserin aut Hyperactivity in patients with narcolepsy and idiopathic hypersomnia: an exploratory study 2023 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier © The Author(s) 2023 Introduction Patients with either Idiopathic Hypersomnia or Narcolepsy demonstrate excessive daytime somnolence (EDS) with resultant inattention mimicking Attention Deficit Hyperactivity Disorder (ADHD). Patients with ADHD also often express sleep problems including EDS. Thus, patients with ADHD and patients with idiopathic hypersomnia or narcolepsy may share inattention and daytime drowsiness as common features. However, it is not known whether EDS patients with idiopathic hypersomnia or narcolepsy also have increased movement (hyperactivity) like ADHD patients, the determination of which is the purpose of this study. Methods We studied 12 patients (7 Narcolepsy type 2 and 5 Idiopathic Hypersomnia) with EDS as shown by Multiple Sleep Latency Test which served as the gold standard for entry into the study. Twelve subjects without symptoms of EDS served as the control group. None of the participants had a previous history of ADHD. Each participant underwent a one-hour session laying at 45 degrees with surveys about the need to move and actigraphy as an objective measure of movement. Results Sleep-disordered patients with EDS reported more symptoms of inattention and hyperactivity on the ADHD Self-Report Scale. At each of the time points patients with EDS had a clear trend to express the need to move more than controls on the Suggested Immobilization Test (SIT). For the total 60 min, a large effect size for the need to move during the SIT test was found between patients and controls (Cohen’s d = 0.61, p = 0.01). Patients with EDS did not express a need to move more to combat drowsiness than controls, nor did actigraphy show any difference in objective movement between patients and controls during the SIT. Conclusion Patients with EDS express inattention and a need to move more than controls. However, hyperactivity was not verified by objective measurement, nor did the EDS patients express a need to move to combat drowsiness more than controls. Thus, a hypothesis to be further tested, is whether narcolepsy and idiopathic hypersomnia may be more a model of the inattentive form of ADHD rather than the combined or inattentive/hyperactive form of ADHD. Further studies are needed to explore the relationship between EDS and hyperactivity. Narcolepsy (dpeaa)DE-He213 Idiopathic hypersomnia (dpeaa)DE-He213 Attention-Deficit Hyperactivity Disorder (ADHD) (dpeaa)DE-He213 Inattention (dpeaa)DE-He213 Hyperactivity (dpeaa)DE-He213 Hypoarousal (dpeaa)DE-He213 Sleepiness (dpeaa)DE-He213 Drowsiness (dpeaa)DE-He213 Somnolence (dpeaa)DE-He213 Suggested Immobilization Test (SIT) (dpeaa)DE-He213 Spruyt, Karen aut Considine, Ciaran aut Thompson, Emily aut Ipsiroglu, Osman S. aut Bagai, Kanika aut Silvestri, Rosalia aut Couvadelli, Barbara aut Walters, Arthur S. aut Enthalten in Sleep science and practice [London] : BioMed Central, 2017 7(2023), 1 vom: 21. Juli (DE-627)880932333 (DE-600)2885817-7 2398-2683 nnns volume:7 year:2023 number:1 day:21 month:07 https://dx.doi.org/10.1186/s41606-023-00088-y kostenfrei Volltext GBV_USEFLAG_A SYSFLAG_A GBV_SPRINGER GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_2014 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 7 2023 1 21 07
allfieldsGer	10.1186/s41606-023-00088-y doi (DE-627)SPR052341178 (SPR)s41606-023-00088-y-e DE-627 ger DE-627 rakwb eng Dodson, Caroline verfasserin aut Hyperactivity in patients with narcolepsy and idiopathic hypersomnia: an exploratory study 2023 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier © The Author(s) 2023 Introduction Patients with either Idiopathic Hypersomnia or Narcolepsy demonstrate excessive daytime somnolence (EDS) with resultant inattention mimicking Attention Deficit Hyperactivity Disorder (ADHD). Patients with ADHD also often express sleep problems including EDS. Thus, patients with ADHD and patients with idiopathic hypersomnia or narcolepsy may share inattention and daytime drowsiness as common features. However, it is not known whether EDS patients with idiopathic hypersomnia or narcolepsy also have increased movement (hyperactivity) like ADHD patients, the determination of which is the purpose of this study. Methods We studied 12 patients (7 Narcolepsy type 2 and 5 Idiopathic Hypersomnia) with EDS as shown by Multiple Sleep Latency Test which served as the gold standard for entry into the study. Twelve subjects without symptoms of EDS served as the control group. None of the participants had a previous history of ADHD. Each participant underwent a one-hour session laying at 45 degrees with surveys about the need to move and actigraphy as an objective measure of movement. Results Sleep-disordered patients with EDS reported more symptoms of inattention and hyperactivity on the ADHD Self-Report Scale. At each of the time points patients with EDS had a clear trend to express the need to move more than controls on the Suggested Immobilization Test (SIT). For the total 60 min, a large effect size for the need to move during the SIT test was found between patients and controls (Cohen’s d = 0.61, p = 0.01). Patients with EDS did not express a need to move more to combat drowsiness than controls, nor did actigraphy show any difference in objective movement between patients and controls during the SIT. Conclusion Patients with EDS express inattention and a need to move more than controls. However, hyperactivity was not verified by objective measurement, nor did the EDS patients express a need to move to combat drowsiness more than controls. Thus, a hypothesis to be further tested, is whether narcolepsy and idiopathic hypersomnia may be more a model of the inattentive form of ADHD rather than the combined or inattentive/hyperactive form of ADHD. Further studies are needed to explore the relationship between EDS and hyperactivity. Narcolepsy (dpeaa)DE-He213 Idiopathic hypersomnia (dpeaa)DE-He213 Attention-Deficit Hyperactivity Disorder (ADHD) (dpeaa)DE-He213 Inattention (dpeaa)DE-He213 Hyperactivity (dpeaa)DE-He213 Hypoarousal (dpeaa)DE-He213 Sleepiness (dpeaa)DE-He213 Drowsiness (dpeaa)DE-He213 Somnolence (dpeaa)DE-He213 Suggested Immobilization Test (SIT) (dpeaa)DE-He213 Spruyt, Karen aut Considine, Ciaran aut Thompson, Emily aut Ipsiroglu, Osman S. aut Bagai, Kanika aut Silvestri, Rosalia aut Couvadelli, Barbara aut Walters, Arthur S. aut Enthalten in Sleep science and practice [London] : BioMed Central, 2017 7(2023), 1 vom: 21. Juli (DE-627)880932333 (DE-600)2885817-7 2398-2683 nnns volume:7 year:2023 number:1 day:21 month:07 https://dx.doi.org/10.1186/s41606-023-00088-y kostenfrei Volltext GBV_USEFLAG_A SYSFLAG_A GBV_SPRINGER GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_2014 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 7 2023 1 21 07
allfieldsSound	10.1186/s41606-023-00088-y doi (DE-627)SPR052341178 (SPR)s41606-023-00088-y-e DE-627 ger DE-627 rakwb eng Dodson, Caroline verfasserin aut Hyperactivity in patients with narcolepsy and idiopathic hypersomnia: an exploratory study 2023 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier © The Author(s) 2023 Introduction Patients with either Idiopathic Hypersomnia or Narcolepsy demonstrate excessive daytime somnolence (EDS) with resultant inattention mimicking Attention Deficit Hyperactivity Disorder (ADHD). Patients with ADHD also often express sleep problems including EDS. Thus, patients with ADHD and patients with idiopathic hypersomnia or narcolepsy may share inattention and daytime drowsiness as common features. However, it is not known whether EDS patients with idiopathic hypersomnia or narcolepsy also have increased movement (hyperactivity) like ADHD patients, the determination of which is the purpose of this study. Methods We studied 12 patients (7 Narcolepsy type 2 and 5 Idiopathic Hypersomnia) with EDS as shown by Multiple Sleep Latency Test which served as the gold standard for entry into the study. Twelve subjects without symptoms of EDS served as the control group. None of the participants had a previous history of ADHD. Each participant underwent a one-hour session laying at 45 degrees with surveys about the need to move and actigraphy as an objective measure of movement. Results Sleep-disordered patients with EDS reported more symptoms of inattention and hyperactivity on the ADHD Self-Report Scale. At each of the time points patients with EDS had a clear trend to express the need to move more than controls on the Suggested Immobilization Test (SIT). For the total 60 min, a large effect size for the need to move during the SIT test was found between patients and controls (Cohen’s d = 0.61, p = 0.01). Patients with EDS did not express a need to move more to combat drowsiness than controls, nor did actigraphy show any difference in objective movement between patients and controls during the SIT. Conclusion Patients with EDS express inattention and a need to move more than controls. However, hyperactivity was not verified by objective measurement, nor did the EDS patients express a need to move to combat drowsiness more than controls. Thus, a hypothesis to be further tested, is whether narcolepsy and idiopathic hypersomnia may be more a model of the inattentive form of ADHD rather than the combined or inattentive/hyperactive form of ADHD. Further studies are needed to explore the relationship between EDS and hyperactivity. Narcolepsy (dpeaa)DE-He213 Idiopathic hypersomnia (dpeaa)DE-He213 Attention-Deficit Hyperactivity Disorder (ADHD) (dpeaa)DE-He213 Inattention (dpeaa)DE-He213 Hyperactivity (dpeaa)DE-He213 Hypoarousal (dpeaa)DE-He213 Sleepiness (dpeaa)DE-He213 Drowsiness (dpeaa)DE-He213 Somnolence (dpeaa)DE-He213 Suggested Immobilization Test (SIT) (dpeaa)DE-He213 Spruyt, Karen aut Considine, Ciaran aut Thompson, Emily aut Ipsiroglu, Osman S. aut Bagai, Kanika aut Silvestri, Rosalia aut Couvadelli, Barbara aut Walters, Arthur S. aut Enthalten in Sleep science and practice [London] : BioMed Central, 2017 7(2023), 1 vom: 21. Juli (DE-627)880932333 (DE-600)2885817-7 2398-2683 nnns volume:7 year:2023 number:1 day:21 month:07 https://dx.doi.org/10.1186/s41606-023-00088-y kostenfrei Volltext GBV_USEFLAG_A SYSFLAG_A GBV_SPRINGER GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_2014 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 7 2023 1 21 07
language	English
source	Enthalten in Sleep science and practice 7(2023), 1 vom: 21. Juli volume:7 year:2023 number:1 day:21 month:07
sourceStr	Enthalten in Sleep science and practice 7(2023), 1 vom: 21. Juli volume:7 year:2023 number:1 day:21 month:07
format_phy_str_mv	Article
institution	findex.gbv.de
topic_facet	Narcolepsy Idiopathic hypersomnia Attention-Deficit Hyperactivity Disorder (ADHD) Inattention Hyperactivity Hypoarousal Sleepiness Drowsiness Somnolence Suggested Immobilization Test (SIT)
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container_title	Sleep science and practice
authorswithroles_txt_mv	Dodson, Caroline @@aut@@ Spruyt, Karen @@aut@@ Considine, Ciaran @@aut@@ Thompson, Emily @@aut@@ Ipsiroglu, Osman S. @@aut@@ Bagai, Kanika @@aut@@ Silvestri, Rosalia @@aut@@ Couvadelli, Barbara @@aut@@ Walters, Arthur S. @@aut@@
publishDateDaySort_date	2023-07-21T00:00:00Z
hierarchy_top_id	880932333
id	SPR052341178
language_de	englisch
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Patients with ADHD also often express sleep problems including EDS. Thus, patients with ADHD and patients with idiopathic hypersomnia or narcolepsy may share inattention and daytime drowsiness as common features. However, it is not known whether EDS patients with idiopathic hypersomnia or narcolepsy also have increased movement (hyperactivity) like ADHD patients, the determination of which is the purpose of this study. Methods We studied 12 patients (7 Narcolepsy type 2 and 5 Idiopathic Hypersomnia) with EDS as shown by Multiple Sleep Latency Test which served as the gold standard for entry into the study. Twelve subjects without symptoms of EDS served as the control group. None of the participants had a previous history of ADHD. Each participant underwent a one-hour session laying at 45 degrees with surveys about the need to move and actigraphy as an objective measure of movement. Results Sleep-disordered patients with EDS reported more symptoms of inattention and hyperactivity on the ADHD Self-Report Scale. At each of the time points patients with EDS had a clear trend to express the need to move more than controls on the Suggested Immobilization Test (SIT). For the total 60 min, a large effect size for the need to move during the SIT test was found between patients and controls (Cohen’s d = 0.61, p = 0.01). Patients with EDS did not express a need to move more to combat drowsiness than controls, nor did actigraphy show any difference in objective movement between patients and controls during the SIT. Conclusion Patients with EDS express inattention and a need to move more than controls. However, hyperactivity was not verified by objective measurement, nor did the EDS patients express a need to move to combat drowsiness more than controls. 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author	Dodson, Caroline
spellingShingle	Dodson, Caroline misc Narcolepsy misc Idiopathic hypersomnia misc Attention-Deficit Hyperactivity Disorder (ADHD) misc Inattention misc Hyperactivity misc Hypoarousal misc Sleepiness misc Drowsiness misc Somnolence misc Suggested Immobilization Test (SIT) Hyperactivity in patients with narcolepsy and idiopathic hypersomnia: an exploratory study
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topic_title	Hyperactivity in patients with narcolepsy and idiopathic hypersomnia: an exploratory study Narcolepsy (dpeaa)DE-He213 Idiopathic hypersomnia (dpeaa)DE-He213 Attention-Deficit Hyperactivity Disorder (ADHD) (dpeaa)DE-He213 Inattention (dpeaa)DE-He213 Hyperactivity (dpeaa)DE-He213 Hypoarousal (dpeaa)DE-He213 Sleepiness (dpeaa)DE-He213 Drowsiness (dpeaa)DE-He213 Somnolence (dpeaa)DE-He213 Suggested Immobilization Test (SIT) (dpeaa)DE-He213
topic	misc Narcolepsy misc Idiopathic hypersomnia misc Attention-Deficit Hyperactivity Disorder (ADHD) misc Inattention misc Hyperactivity misc Hypoarousal misc Sleepiness misc Drowsiness misc Somnolence misc Suggested Immobilization Test (SIT)
topic_unstemmed	misc Narcolepsy misc Idiopathic hypersomnia misc Attention-Deficit Hyperactivity Disorder (ADHD) misc Inattention misc Hyperactivity misc Hypoarousal misc Sleepiness misc Drowsiness misc Somnolence misc Suggested Immobilization Test (SIT)
topic_browse	misc Narcolepsy misc Idiopathic hypersomnia misc Attention-Deficit Hyperactivity Disorder (ADHD) misc Inattention misc Hyperactivity misc Hypoarousal misc Sleepiness misc Drowsiness misc Somnolence misc Suggested Immobilization Test (SIT)
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title	Hyperactivity in patients with narcolepsy and idiopathic hypersomnia: an exploratory study
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title_full	Hyperactivity in patients with narcolepsy and idiopathic hypersomnia: an exploratory study
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author_browse	Dodson, Caroline Spruyt, Karen Considine, Ciaran Thompson, Emily Ipsiroglu, Osman S. Bagai, Kanika Silvestri, Rosalia Couvadelli, Barbara Walters, Arthur S.
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title_sort	hyperactivity in patients with narcolepsy and idiopathic hypersomnia: an exploratory study
title_auth	Hyperactivity in patients with narcolepsy and idiopathic hypersomnia: an exploratory study
abstract	Introduction Patients with either Idiopathic Hypersomnia or Narcolepsy demonstrate excessive daytime somnolence (EDS) with resultant inattention mimicking Attention Deficit Hyperactivity Disorder (ADHD). Patients with ADHD also often express sleep problems including EDS. Thus, patients with ADHD and patients with idiopathic hypersomnia or narcolepsy may share inattention and daytime drowsiness as common features. However, it is not known whether EDS patients with idiopathic hypersomnia or narcolepsy also have increased movement (hyperactivity) like ADHD patients, the determination of which is the purpose of this study. Methods We studied 12 patients (7 Narcolepsy type 2 and 5 Idiopathic Hypersomnia) with EDS as shown by Multiple Sleep Latency Test which served as the gold standard for entry into the study. Twelve subjects without symptoms of EDS served as the control group. None of the participants had a previous history of ADHD. Each participant underwent a one-hour session laying at 45 degrees with surveys about the need to move and actigraphy as an objective measure of movement. Results Sleep-disordered patients with EDS reported more symptoms of inattention and hyperactivity on the ADHD Self-Report Scale. At each of the time points patients with EDS had a clear trend to express the need to move more than controls on the Suggested Immobilization Test (SIT). For the total 60 min, a large effect size for the need to move during the SIT test was found between patients and controls (Cohen’s d = 0.61, p = 0.01). Patients with EDS did not express a need to move more to combat drowsiness than controls, nor did actigraphy show any difference in objective movement between patients and controls during the SIT. Conclusion Patients with EDS express inattention and a need to move more than controls. However, hyperactivity was not verified by objective measurement, nor did the EDS patients express a need to move to combat drowsiness more than controls. Thus, a hypothesis to be further tested, is whether narcolepsy and idiopathic hypersomnia may be more a model of the inattentive form of ADHD rather than the combined or inattentive/hyperactive form of ADHD. Further studies are needed to explore the relationship between EDS and hyperactivity. © The Author(s) 2023
abstractGer	Introduction Patients with either Idiopathic Hypersomnia or Narcolepsy demonstrate excessive daytime somnolence (EDS) with resultant inattention mimicking Attention Deficit Hyperactivity Disorder (ADHD). Patients with ADHD also often express sleep problems including EDS. Thus, patients with ADHD and patients with idiopathic hypersomnia or narcolepsy may share inattention and daytime drowsiness as common features. However, it is not known whether EDS patients with idiopathic hypersomnia or narcolepsy also have increased movement (hyperactivity) like ADHD patients, the determination of which is the purpose of this study. Methods We studied 12 patients (7 Narcolepsy type 2 and 5 Idiopathic Hypersomnia) with EDS as shown by Multiple Sleep Latency Test which served as the gold standard for entry into the study. Twelve subjects without symptoms of EDS served as the control group. None of the participants had a previous history of ADHD. Each participant underwent a one-hour session laying at 45 degrees with surveys about the need to move and actigraphy as an objective measure of movement. Results Sleep-disordered patients with EDS reported more symptoms of inattention and hyperactivity on the ADHD Self-Report Scale. At each of the time points patients with EDS had a clear trend to express the need to move more than controls on the Suggested Immobilization Test (SIT). For the total 60 min, a large effect size for the need to move during the SIT test was found between patients and controls (Cohen’s d = 0.61, p = 0.01). Patients with EDS did not express a need to move more to combat drowsiness than controls, nor did actigraphy show any difference in objective movement between patients and controls during the SIT. Conclusion Patients with EDS express inattention and a need to move more than controls. However, hyperactivity was not verified by objective measurement, nor did the EDS patients express a need to move to combat drowsiness more than controls. Thus, a hypothesis to be further tested, is whether narcolepsy and idiopathic hypersomnia may be more a model of the inattentive form of ADHD rather than the combined or inattentive/hyperactive form of ADHD. Further studies are needed to explore the relationship between EDS and hyperactivity. © The Author(s) 2023
abstract_unstemmed	Introduction Patients with either Idiopathic Hypersomnia or Narcolepsy demonstrate excessive daytime somnolence (EDS) with resultant inattention mimicking Attention Deficit Hyperactivity Disorder (ADHD). Patients with ADHD also often express sleep problems including EDS. Thus, patients with ADHD and patients with idiopathic hypersomnia or narcolepsy may share inattention and daytime drowsiness as common features. However, it is not known whether EDS patients with idiopathic hypersomnia or narcolepsy also have increased movement (hyperactivity) like ADHD patients, the determination of which is the purpose of this study. Methods We studied 12 patients (7 Narcolepsy type 2 and 5 Idiopathic Hypersomnia) with EDS as shown by Multiple Sleep Latency Test which served as the gold standard for entry into the study. Twelve subjects without symptoms of EDS served as the control group. None of the participants had a previous history of ADHD. Each participant underwent a one-hour session laying at 45 degrees with surveys about the need to move and actigraphy as an objective measure of movement. Results Sleep-disordered patients with EDS reported more symptoms of inattention and hyperactivity on the ADHD Self-Report Scale. At each of the time points patients with EDS had a clear trend to express the need to move more than controls on the Suggested Immobilization Test (SIT). For the total 60 min, a large effect size for the need to move during the SIT test was found between patients and controls (Cohen’s d = 0.61, p = 0.01). Patients with EDS did not express a need to move more to combat drowsiness than controls, nor did actigraphy show any difference in objective movement between patients and controls during the SIT. Conclusion Patients with EDS express inattention and a need to move more than controls. However, hyperactivity was not verified by objective measurement, nor did the EDS patients express a need to move to combat drowsiness more than controls. Thus, a hypothesis to be further tested, is whether narcolepsy and idiopathic hypersomnia may be more a model of the inattentive form of ADHD rather than the combined or inattentive/hyperactive form of ADHD. Further studies are needed to explore the relationship between EDS and hyperactivity. © The Author(s) 2023
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title_short	Hyperactivity in patients with narcolepsy and idiopathic hypersomnia: an exploratory study
url	https://dx.doi.org/10.1186/s41606-023-00088-y
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author2	Spruyt, Karen Considine, Ciaran Thompson, Emily Ipsiroglu, Osman S. Bagai, Kanika Silvestri, Rosalia Couvadelli, Barbara Walters, Arthur S.
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